Vaccines pneumococcal pneumonia streptococcus pneumoniae meningitis pneumococcal. Medical search

Meningitis, Pneumococcal: An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)Streptococcus pneumoniae: A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.Pneumonia, Pneumococcal: A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.Ceftriaxone: A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Cerebrospinal Fluid: A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.Meningitis, Bacterial: Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.Streptococcus: A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.Pneumonia: Infection of the lung often accompanied by inflammation.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Streptolysins: Exotoxins produced by certain strains of streptococci, particularly those of group A (STREPTOCOCCUS PYOGENES), that cause HEMOLYSIS.Klebsiella pneumoniae: Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.Pneumonia, Bacterial: Inflammation of the lung parenchyma that is caused by bacterial infections.Streptococcus pyogenes: A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.Pneumococcal Vaccines: Vaccines or candidate vaccines used to prevent infections with STREPTOCOCCUS PNEUMONIAE.Streptococcus mutans: A polysaccharide-producing species of STREPTOCOCCUS isolated from human dental plaque.Meningitis, Aseptic: A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745)Mycoplasma pneumoniae: Short filamentous organism of the genus Mycoplasma, which binds firmly to the cells of the respiratory epithelium. It is one of the etiologic agents of non-viral primary atypical pneumonia in man.Vaccines: Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Penicillin Resistance: Nonsusceptibility of an organism to the action of penicillins.Community-Acquired Infections: Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.Streptococcal Infections: Infections with bacteria of the genus STREPTOCOCCUS.Serotyping: Process of determining and distinguishing species of bacteria or viruses based on antigens they share.Bacterial Proteins: Proteins found in any species of bacterium.Nasopharynx: The top portion of the pharynx situated posterior to the nose and superior to the SOFT PALATE. The nasopharynx is the posterior extension of the nasal cavities and has a respiratory function.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Streptococcus agalactiae: A bacterium which causes mastitis in cattle and occasionally in man.Meningitis, Viral: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)Pneumonia, Viral: Inflammation of the lung parenchyma that is caused by a viral infection.Bacterial Vaccines: Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.Vaccines, Conjugate: Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.Penicillins: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Meningitis, Haemophilus: Infections of the nervous system caused by bacteria of the genus HAEMOPHILUS, and marked by prominent inflammation of the MENINGES. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults.Bacterial Capsules: An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.Pneumonia, Mycoplasma: Interstitial pneumonia caused by extensive infection of the lungs (LUNG) and BRONCHI, particularly the lower lobes of the lungs, by MYCOPLASMA PNEUMONIAE in humans. In SHEEP, it is caused by MYCOPLASMA OVIPNEUMONIAE. In CATTLE, it may be caused by MYCOPLASMA DISPAR.Vaccines, Inactivated: Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.Meningitis, Meningococcal: A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)Meningitis, Fungal: Meningitis caused by fungal agents which may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts.Macrolides: A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Drug Resistance, Bacterial: The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Anti-Infective Agents: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.Streptococcus mitis: A species of gram-positive, coccoid bacteria commensal in the respiratory tract.Fluoroquinolones: A group of QUINOLONES with at least one fluorine atom and a piperazinyl group.Viral Vaccines: Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.Cefotaxime: Semisynthetic broad-spectrum cephalosporin.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Polysaccharides, Bacterial: Polysaccharides found in bacteria and in capsules thereof.Streptococcus suis: A species of STREPTOCOCCUS isolated from pigs. It is a pathogen of swine but rarely occurs in humans.Vaccines, Synthetic: Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified.Meningitis, Cryptococcal: Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)Colony Count, Microbial: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.Vaccines, Combined: Two or more vaccines in a single dosage form.Streptococcus oralis: A species of gram-positive, coccoid bacteria that is numerous in the mouth and throat. It is a common cause of endocarditis and is also implicated in dental plaque formation.Vaccines, DNA: Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.Haemophilus influenzae: A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.Vaccination: Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.Erythromycin: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Levofloxacin: The L-isomer of Ofloxacin.Streptococcus Phages: Viruses whose host is Streptococcus.Cephalosporin Resistance: Non-susceptibility of an organism to the action of the cephalosporins.Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Streptococcus bovis: A species of gram-positive, coccoid bacteria commonly found in the alimentary tract of cows, sheep, and other ruminants. It occasionally is encountered in cases of human endocarditis. This species is nonhemolytic.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.N-Acetylmuramoyl-L-alanine Amidase: An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.Tuberculosis, Meningeal: A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)Klebsiella Infections: Infections with bacteria of the genus KLEBSIELLA.Streptococcal Vaccines: Vaccines or candidate vaccines used to prevent STREPTOCOCCAL INFECTIONS.Cryptogenic Organizing Pneumonia: An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.AIDS Vaccines: Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent or treat AIDS. Some vaccines containing antigens are recombinantly produced.Carrier State: The condition of harboring an infective organism without manifesting symptoms of infection. The organism must be readily transmissible to another susceptible host.Empyema: Presence of pus in a hollow organ or body cavity.Streptococcus equi: A species of gram-positive, coccoid bacteria isolated from abscesses in submaxillary glands and mucopurulent discharges of the upper respiratory tract of horses. This organism belongs to Group C streptococci with regards to antigen response and is known to cause strangles. The subspecies S. zooepidemicus is also considered a pathogen of horses.Vaccines, Subunit: Vaccines consisting of one or more antigens that stimulate a strong immune response. They are purified from microorganisms or produced by recombinant DNA techniques, or they can be chemically synthesized peptides.Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Ketolides: Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Blood: The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.Pneumonia, Pneumocystis: A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.Genes, Bacterial: The functional hereditary units of BACTERIA.Transformation, Bacterial: The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.Mice, Inbred BALB C Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Meningococcal Vaccines: Vaccines or candidate vaccines used to prevent infection with NEISSERIA MENINGITIDIS.Pneumonia, Staphylococcal: Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.Counterimmunoelectrophoresis: Immunoelectrophoresis in which immunoprecipitation occurs when antigen at the cathode is caused to migrate in an electric field through a suitable medium of diffusion against a stream of antibody migrating from the anode as a result of endosmotic flow.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Moraxella (Branhamella) catarrhalis: Gram-negative aerobic cocci of low virulence that colonize the nasopharynx and occasionally cause MENINGITIS; BACTEREMIA; EMPYEMA; PERICARDITIS; and PNEUMONIA.Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Penicillin-Binding Proteins: Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.Naphthyridines Mice, Inbred C57BLHaemophilus Infections: Infections with bacteria of the genus HAEMOPHILUS.Sputum: Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.Streptococcus sobrinus: A species of gram-positive, coccoid bacteria isolated from the human tooth surface. Strains have been shown to be cariogenic in experimental animals and may be associated with human dental caries.DNA Topoisomerase IV: A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.Aminoacyltransferases: Enzymes that catalyze the transfer of an aminoacyl group from donor to acceptor resulting in the formation of an ester or amide linkage. EC 2.3.2.Gram-Positive Bacteria: Bacteria which retain the crystal violet stain when treated by Gram's method.

List of vaccine topics

Streptococcus pneumoniae. Pneumococcal pneumonia. Pneumococcal conjugate vaccine, Pneumococcal polysaccharide vaccine. ... Q fever vaccine. Q-Vax Haemophilus influenzae type B (Hib). Epiglottitis, meningitis, pneumonia. Hib vaccine. Hiberix, Pentacel ... Rotavirus vaccine. Rotateq, Rotarix Rubella virus. Rubella. Rubella vaccine, MMR vaccine, MMRV vaccine. Priorix, MMR II, ... Japanese encephalitis vaccine. Ixiaro, Jespect, Imojev Measles virus. Measles. Measles vaccine, MMR vaccine, MMRV vaccine. ...

Pneumococcal vaccine

Pneumococcal vaccines are vaccines against the bacteria Streptococcus pneumoniae. Their use can prevent some cases of pneumonia ... meningitis, and sepsis. There are two types of pneumococcal vaccines: conjugate vaccines and polysaccharide vaccines. They are ... Additional pneumococcal vaccine research is taking place to find a vaccine that offers broad protection against pneumococcal ... "Pneumococcal AMC GAVI webpage" Archived 2013-06-07 at the Wayback Machine. "Pneumonia vaccine to be part of immunisation drive ...

Pneumococcal Awareness Council of Experts

">"Childhood Pneumonia & Meningitis: Recent Advances". "Sabin Vaccine Institute's 4th Regional Pneumococcal Symposium". ... "Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates" "PACE Call to Action ... Sabin.org/PACE Pneumococcal disease Pneumococcal vaccines World Pneumonia Day PATH PneumoADIP. ... As the three leading causes of bacterial meningitis in childhood are vaccine preventable, the regular use of conjugate vaccines ...

Pneumococcal conjugate vaccine

Streptococcus pneumoniae Pneumonia PneumoADIP Pneumococcal polysaccharide vaccine "Pneumococcal 7-valent Conjugate Vaccine ( ... "Changing epidemiology of pneumococcal meningitis after the introduction of pneumococcal conjugate vaccine in the United States ... Pneumococcal conjugate vaccine (PCV) is a pneumococcal vaccine and a conjugate vaccine used to protect infants, young children ... World Health Organization: Pneumococcal vaccines Pneumococcal conjugate vaccine at Curlie (based on DMOZ). ...

Samir Kumar Saha

"Streptococcus pneumoniae Serotype-2 Childhood Meningitis in Bangladesh: A Newly Recognized Pneumococcal Infection Threat". PLOS ... Saha played a key role in implementing vaccines against two bacteria that cause meningitis and pneumonia in Bangladesh. It had ... mostly exploring the topics of childhood pneumonia and meningitis. A member of Pneumococcal Awareness Council of Experts (PACE ... "The Life-Saving Vaccine the World Has Never Heard Of... - Stop Pneumonia". stoppneumonia.org. Retrieved 2018-01-09. User, Super ...

Streptococcus pneumoniae

Vaccine[edit]. Main article: Pneumococcal vaccine. Due to the importance of disease caused by S. pneumoniae, several vaccines ... S. pneumoniae is the main cause of community acquired pneumonia and meningitis in children and the elderly,[5] and of ... penicillin-resistant Streptococcus pneumoniae (PRSP)[33], Streptococcus pneumoniae penicillin resistant (SPPR)[34] or drug- ... It was renamed Streptococcus pneumoniae in 1974 because it was very similar to streptococci.[7][11] ...

Pneumococcal pneumonia

... is a type of bacterial pneumonia that is specifically caused by Streptococcus pneumoniae. S. pneumoniae ... A vaccine has also been developed for the prevention of pneumococcal pneumonia, recommended to children under age five as well ... While it has been commonly known that the influenza virus increases one's chances of contracting pneumonia or meningitis caused ... "Pneumococcal Pneumonia". www.niaid.nih.gov. Retrieved 2016-04-26. "Pneumococcal Disease , Facts About Pneumonia , CDC". www.cdc ...

Streptococcus pneumoniae

S. pneumoniae is the main cause of community acquired pneumonia and meningitis in children and the elderly, and of septicemia ... 16: Pneumococcal Disease". In Atkinson W; Wolfe S; Hamborsky J. Epidemiology and Prevention of Vaccine-Preventable Diseases ( ... It was renamed Streptococcus pneumoniae in 1974 because it was very similar to streptococci. S. pneumoniae played a central ... Optochin sensitivity in a culture of Streptococcus pneumoniae Natural competence Transformation (genetics) Pneumococcal ...

George Siber

... a pneumococcal vaccine, Acel-Imune, an acellular pertussis vaccine, Meningitec, a meningococcal meningitis vaccine, Rotashield ... "Immunization Against Streptococcus pneumoniae" filed May 8, 2006 U. S. patent number 8,617,564 - Vaccines against herpes ... the first Pneumococcal Pneumonia Conjugate. Respigam was the first antibody licensed for preventing severe RSV infections in ... 2008). Pneumococcal vaccines: the impact of conjugate vaccine. Washington, DC: ASM Press. ISBN 9781555814083. George Siber's ...

Pneumococcal infection

... pneumoniae. In 1936, a pneumococcal capsular polysaccharide vaccine was used to abort an epidemic of pneumococcal pneumonia. In ... Pneumococcal infection is an infection caused by the bacterium Streptococcus pneumoniae. S. pneumoniae is a common member of ... However, it is also the cause of significant disease being a leading cause of pneumonia, bacterial meningitis, and sepsis. The ... November 2nd: World Pneumonia Day Website Pneumococcal Vaccine Accelerated Development and Introduction Plan. ...

Claire V. Broome

... responsible for funding and implementing a research portfolio on vaccines needed to prevent bacterial meningitis and pneumonia ... Epidemiology of clinically significant isolates of Streptococcus pneumoniae in the United States. Rev Infect Dis 1981;3:277 280 ... Pneumococcal disease after pneumococcal vaccination: an alternative method to estimate the efficacy of pneumococcal vaccine. N ... Group B meningococcal vaccine efficacy in Cuba; and Haemophilus influenza type b conjugate vaccine impact on pneumonia in the ...

Childhood immunizations in the United States

Pneumococcal disease is caused by the bacteria Streptococcus pneumoniae also known as Pneumococcus. This bacteria can cause ... This vaccine protects against Hib, but not the other strains of Haemphilus Influenza Type B. It prevents meningitis, Hib ... 1 in 4 get pneumonia 1 or 2 in 100 will have convulsions (violent, uncontrolled shaking) 2/3 will have apnea 1 in 300 will have ... Pneumococcal Vaccine Side Effects Pneumococcal Side Effects Pneumococcal Treatment CDC Polio Polio vaccine Polio Vaccine Side ...

Robert Austrian

... which describes the clinical syndrome of pneumococcal meningitis, pneumonia and endocarditis, after his 1957 paper in Archives ... one of the 2 most important researchers into the biology of Streptococcus pneumoniae in the 20th century.[citation needed] ... When antibiotics came into use for the cure of pneumococcal infections in the 1950s and 60s, further pneumococcal vaccine ... His Lasker award reads as follows "For his persistent, dedicated efforts which permitted the development of a vaccine that soon ...

Oxford Vaccine Group

... and pneumonia, and evaluating carriage of Hib disease and Streptococcus pneumoniae. 2006: a study looking at the effectiveness ... The Group has also carried out research on pneumococcal vaccines, typhoid vaccines and, more recently, new vaccines against ... Vaccine 2009 Nov 16;27(49):6918-25. Fergus Walsh (20 October 2006). "Meningitis B vaccine trials begin". BBC News. Retrieved 25 ... "Doctors hail meningitis vaccine 'breakthrough'". The Guardian. Retrieved 25 June 2015. Primary Care and Vaccines Collaborative ...

Streptococcus pneumoniae

Peterson LR (2006). "Penicillins for treatment of pneumococcal pneumonia: does in vitro resistance really matter?". Clin Infect ... Dagan R. "Treatment of acute otitis media - challenges in the era of antibiotic resistance". Vaccine. 19 Suppl 1: S9-S16. ... Neisseria meningitis, Staphylococcus aureus, Haemophilus influenzae). ... Streptococcus pneumoniae, diplococcus pneumoniae, ose thjesht pneumococcus janë baktere diplokoke gram-pozitive të rradhitura ...

George Siber bibliography

"Design of a group-randomized Streptococcus pneumoniae vaccine trial". Controlled Clinical Trials. 22 (4): 438-52. doi:10.1016/ ... Previous pneumococcal polysaccharide vaccine impacts immune response to subsequent pneumococcal conjugate vaccine in the ... "Haemophilus influenzae type b meningitis after three doses of vaccine". The Lancet. 343 (8900): 794. doi:10.1016/s0140-6736(94) ... Efficacy of Heptavalent Conjugate Pneumococal Vaccine (Wyeth Lederle) in 37,000 infants and children: Impact on Pneumonia, ...

Streptococcus

meningitis. S. mitis. human. endocarditis. S. mutans. human. dental caries. S. pneumoniae. human. pneumonia. ... Cohen-Poradosu R, Kasper DL (2007). "Group A streptococcus epidemiology and vaccine implications". Clin. Infect. Dis. 45 (7): ... Tiraby JG, Tiraby E, Fox MS (1975) Pneumococcal bacteriophages. Virology 68:566-569 ... Streptococcus pneumoniae and a group of oral streptococci (Streptococcus viridans or viridans streptococci) display alpha ...

Urinary tract infection

Streptococcus. α. optochin susceptible. *S. pneumoniae *Pneumococcal infection. optochin resistant. *Viridans streptococci: S. ... Magistro, G; Stief, CG (6 August 2018). "Vaccine Development for Urinary Tract Infections: Where Do We Stand?". European ... Klebsiella pneumoniae *Rhinoscleroma, Pneumonia. *Klebsiella granulomatis *Granuloma inguinale. *Klebsiella oxytoca. * ... Huttner, A; Gambillara, V (24 May 2018). "The development and early clinical testing of the ExPEC4V conjugate vaccine against ...

Streptococcus agalactiae

... pneumonia, and meningitis, which can lead to death or long-term sequelae.[4] ... "Status of vaccine research and development of vaccines for GBS" (PDF). Vaccine. 34: 2876-2879. doi:10.1016/j.vaccine.2015.12. ... Streptococcus. α. optochin susceptible. *S. pneumoniae *Pneumococcal infection. optochin resistant. *Viridans streptococci: S. ... Streptococcus agalactiae. Lehmann and Neumann, 1896. Streptococcus agalactiae (also known as group B streptococcus or GBS) is a ...

Meningitis

Routine vaccination against Streptococcus pneumoniae with the pneumococcal conjugate vaccine (PCV), which is active against ... pneumonia. In adults, too, meningococcal meningitis has a lower mortality (3-7%) than pneumococcal disease. In children there ... The introduction of pneumococcal vaccine has lowered rates of pneumococcal meningitis in both children and adults. Recent skull ... 2009). "Effect of pneumococcal conjugate vaccine on pneumococcal meningitis". N Engl J Med. 360 (3): 244-256. doi:10.1056/ ...

Streptococcus

S. agalactiae, or group B Streptococcus, GBS, causes pneumonia and meningitis in neonates and the elderly, with occasional ... Streptococcus pneumoniae and a group of oral streptococci (Streptococcus viridans or viridans streptococci) display alpha ... Cohen-Poradosu R, Kasper DL (2007). "Group A streptococcus epidemiology and vaccine implications". Clin. Infect. Dis. 45 (7): ... Virology 63:577-582 Tiraby JG, Tiraby E, Fox MS (1975) Pneumococcal bacteriophages. Virology 68:566-569 López R (2004). " ...

Otitis media

Pneumococcal conjugate vaccines (PCV) in early infancy, decreases the risk of acute otitis media in healthy infants. PCV is ... The most common bacteria isolated from the middle ear in AOM are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella ... such as bacterial meningitis, brain abscess, or dural sinus thrombosis. It is estimated that each year 21,000 people die due to ... community-acquired pneumonia and acute otitis media". European Journal of Clinical Microbiology & Infectious Diseases. 32 (2): ...

Scarlet fever

"Initiative for Vaccine Research (IVR)-Group A Streptococcus". World Health Organization. Archived from the original on 13 May ... Streptococcus. α. optochin susceptible. *S. pneumoniae *Pneumococcal infection. optochin resistant. *Viridans streptococci: S. ... A few examples of the many complications which can arise from those methods of spread include endocarditis, pneumonia, or ... meningitis.[15]. Nonsuppurative complications: These complications arise from certain subtypes of the group A streptococci ...

Pathogen

Vaccines against bacterial pathogens include the anthrax vaccine and the pneumococcal vaccine. Many other bacterial pathogens ... such as pneumonia, which can be caused by bacteria such as Streptococcus and Pseudomonas, and foodborne illnesses, which can be ... Neisseria gonorrhoeae and Streptococcus pneumoniae.[44]. Eukaryotic pathogens are often capable of sexual interaction by a ... which can cause a severe form of meningitis. The typical fungal spore size is ,4.7 μm in length, but some spores may be larger. ...

Haemophilus meningitis

... is a form of bacterial meningitis caused by the Haemophilus influenzae bacteria. It is usually (but not always) associated with Haemophilus influenzae type b. Meningitis involves the inflammation of the protective membranes that cover the brain and spinal cord. Haemophilus meningitis is characterized by symptoms including fever, nausea, sensitivity to light, headaches, stiff neck, anorexia, and seizures. Haemophilus meningitis can be deadly, but antibiotics are effective in treating the infection, especially when cases are caught early enough that the inflammation has not done a great deal of damage. Before the introduction of the Hib vaccine in 1985, Haemophilus meningitis was the leading cause of bacterial meningitis in children under the age of five. However, since the creation of the Hib vaccine, only two in every 100,000 children contract this type of meningitis. Five to ten ...

Meningitis

A lumbar puncture is done by positioning the person, usually lying on the side, applying local anesthetic, and inserting a needle into the dural sac (a sac around the spinal cord) to collect cerebrospinal fluid (CSF). When this has been achieved, the "opening pressure" of the CSF is measured using a manometer. The pressure is normally between 6 and 18 cm water (cmH2O);[42] in bacterial meningitis the pressure is usually elevated.[8][41] In cryptococcal meningitis, intracranial pressure is markedly elevated.[45] The initial appearance of the fluid may prove an indication of the nature of the infection: cloudy CSF indicates higher levels of protein, white and red blood cells and/or bacteria, and therefore may suggest bacterial meningitis.[8] The CSF sample is examined for presence and types of white blood cells, red blood cells, protein content and glucose level.[8] Gram staining of the sample may demonstrate bacteria in bacterial meningitis, ...

Neonatal meningitis

7 days of age. After confirmation of GBS, penicillin alone should be used for the rest of the treatment, including the 14-day post-sterilization therapy. For suspected Gram-negative enteric(including E. coli) meningitis a combination of cefotaxime and aminoglycoside, usually gentamicin, is recommended. This treatment should last for 14 days after sterilization and then only cefotaxime for another 7 days creating a minimum of 21 days of therapy post-sterilization. L. meningitis should be treated with a combination of ampicillin and gentamicin because it is synergistic in vitro and provides more rapid bacterial clearance in animal models of infection. After sterilization of CSF, ampicillin should be stopped and gentamicin continued for another 14 days. S. pneumonia can be treated with a combination of penicillin and ampicillin. In cases of herpes simplex virus-derived meningitis, antiviral therapy (acyclovir or vidarabine) must be started ...

Meningitis

... inggih punika lelara amargi wonten infèksi ing meninges ingkang nutupi utek lan sungsum balung belakang.[1] Meninges inggih punika tiga lapisan jaringan ikat ingkang kawangun saking pia mèter (paling celak tumuju organ-organ sistem saraf), arachnoid, lan dura mèter (paling tebih saking utek lan sungsum balung belakang).[1] Meningitis saged dipunjalari déning manéka jinis organisme, kados ta virus, baktèri, utawi jamur ingkang nyebar mlebet wonten salebeting getih lan pindhah tumuju salebeting cuwèran utek ingkang saged njalari meninges aboh.[2] Meninges ingkang aboh punika saged njalari karusakan ingkang wigati ing saraf, utek, lan sungsum balung belakang.[2] ...

Paŋok

... (Maŋok) Paŋok ee tuɛny rëprëëp nyith bud. Aye kɔc kök col Maŋok. Abuöt kënë aye pïu nyith ku köu dhïöt. Pïu kä aye tö kaam rëprëëp Paiya ku Arakanoid. Paŋok aye käm thoy-nyïn apɛi col Bakteryia, Bairäth ku Pangäth bɛi tënë kɔc Paŋok Bakteryia (Bacterial Meningitis) Paŋok aye kuatëkuatic bacteryia bɛi ku akiithic apɛi. Tök ku ye yen miith akël nɔ̈k apɛi aye cɔl Heomophiluɛ Influenza. Dët yen rac apɛi aye acɔl Neisseria Meningitidis ku aye kuat Paŋok cɔl Meningococcus meningitis bëi tënë kɔc. Dët ye kek diäk ku aa bakteryia aya, aye cɔl Streptococcus Pneumoniae. kënë aye kuat Paŋok cɔl Pneumococus bëi. Mïth akël aye paŋok bakteryia yɔŋ arët Paŋok Bairäth (Viral Meningitis) Barääth aye käm kor nyïn apɛi; arëk bakteryia adït keek. Kuat bairääth gäk apɛi paŋok yïëk kɔc akïk: Herpes Simplex aye bairäth kɔc rɔp thook(thoŋ nhial ku piny, gëm ku liep); looi dëtök thokic, kaam amok tënë rööl; ku kaam ...

Likvor - Wikipedija, prosta enciklopedija

V primeru zvišanega CSF tlaka je moten pretok krvi v možganih. Ko pride do problemov v pretoku likvorja to zmoti ne samo likvor sam, temveč tudi stistljivost kraniospinalnega prostora in pretok krvi znotraj lobanje, s posledično ranljivostjo nevronov in glie. Kot je bilo že omenjeno sta cerebrospinalna tekočina in limfni sistem povezana. Primer patologije ki prikazuje odnose med motnjami cerebrospinalne tekočine je primer hidrocefalusa ter motenega CSF limfatičnega transporta. Likvor se lahko testira za diagnozo mnogih nevroloških bolezni, nujno ob sumu na meningitis in subarahnoidalno krvavitev ter je dobra dodatna preiskava ob sumu na multiplo sklerozo ter razne inflamatorne (vnetne) bolezni. To se dela z lumbalno funkcijo. Lumbalna punkcija je postopek, ko zdravnik z injekcijo vbode med dvema vretencema hrbtenice (tretjim in četrtim ledvenim vretencem) in s punkcijo odvzame vzorec cerebrospinalne tekočine-likvorja za nadaljnjo diagnostiko). Pacient ob tem leži na boku, skrčen s ...

Likvor - Wikipedija, prosta enciklopedija

V primeru zvišanega CSF tlaka je moten pretok krvi v možganih. Ko pride do problemov v pretoku likvorja to zmoti ne samo likvor sam, temveč tudi stistljivost kraniospinalnega prostora in pretok krvi znotraj lobanje, s posledično ranljivostjo nevronov in glie.. Kot je bilo že omenjeno sta cerebrospinalna tekočina in limfni sistem povezana. Primer patologije ki prikazuje odnose med motnjami cerebrospinalne tekočine je primer hidrocefalusa ter motenega CSF limfatičnega transporta. Likvor se lahko testira za diagnozo mnogih nevroloških bolezni, nujno ob sumu na meningitis in subarahnoidalno krvavitev ter je dobra dodatna preiskava ob sumu na multiplo sklerozo ter razne inflamatorne (vnetne) bolezni. To se dela z lumbalno funkcijo.. Lumbalna punkcija je postopek, ko zdravnik z injekcijo vbode med dvema vretencema hrbtenice (tretjim in četrtim ledvenim vretencem) in s punkcijo odvzame vzorec cerebrospinalne tekočine-likvorja za nadaljnjo diagnostiko). Pacient ob tem leži na boku, skrčen s ...

Likvor - Wikipedija, prosta enciklopedija

Quellung reaction

The Quellung reaction, also called the Neufeld reaction, is a biochemical reaction in which antibodies bind to the bacterial capsule of Streptococcus pneumoniae, Klebsiella pneumoniae, Neisseria meningitidis, Bacillus anthracis, Haemophilus influenzae, Escherichia coli, and Salmonella. The antibody reaction allows these species to be visualized under a microscope. If the reaction is positive, the capsule becomes opaque and appears to enlarge. Quellung is the German word for "swelling" and describes the microscopic appearance of pneumococcal or other bacterial capsules after their polysaccharide antigen has combined with a specific antibody. The antibody usually comes from a bit of serum taken from an immunized laboratory animal. As a result of this combination, and precipitation of the large, complex molecule formed, the capsule appears to swell, because of increased surface tension, and its outlines become clearly ...

Streptococcus pneumoniae

... , or pneumococcus, is a Gram-positive, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), facultative anaerobic member of the genus Streptococcus.[1] They are usually found in pairs (diplococci) and do not form spores and are nonmotile.[2] As a significant human pathogenic bacterium S. pneumoniae was recognized as a major cause of pneumonia in the late 19th century, and is the subject of many humoral immunity studies. S. pneumoniae resides asymptomatically in healthy carriers typically colonizing the respiratory tract, sinuses, and nasal cavity. However, in susceptible individuals with weaker immune systems, such as the elderly and young children, the bacterium may become pathogenic and spread to other locations to cause disease. It spreads by direct person-to-person contact via respiratory droplets and by autoinoculation in persons carrying the bacteria in their upper respiratory tracts.[3] It can ...

Streptococcus pneumoniae

Natural bacterial transformation involves the transfer of DNA from one bacterium to another through the surrounding medium. Transformation is a complex developmental process requiring energy and is dependent on expression of numerous genes. In S. pneumoniae, at least 23 genes are required for transformation. For a bacterium to bind, take up, and recombine exogenous DNA into its chromosome, it must enter a special physiological state called competence. Competence in S. pneumoniae is induced by DNA-damaging agents such as mitomycin C, fluoroquinolone antibiotics (norfloxacin, levofloxacin and moxifloxacin), and topoisomerase inhibitors.[16] Transformation protects S. pneumoniae against the bactericidal effect of mitomycin C.[17] Michod et al.[18] summarized evidence that induction of competence in S. pneumoniae is associated with increased resistance to oxidative stress and increased expression of the RecA protein, a key component of the ...

Streptococcus pneumoniae

Pneumokoket mund të jenë virulente dhe jo virulente. Kjo varet nga shumë faktor. Faktor kyresor është prania ose jo e kapsulës polisakaridike komplekse e cila e rrethon qelizën pneumokoke. Gjatë invazionit kapsula është esenciale për determinimin e virulencës. Kapsula ndërhyn në procesin e fagocitozës duke parandaluar opsonizimin e qelizës bakterore nga komplementi C3b. Gjatë invazionit të sipërfaqëve mukozale, shtamet e kapsuluara janë 100,000 herë më virulente se sa shtamet e pa kapsuluara. Polisakaridi nuk është toksik dhe inflamator. Përveç kapsulës, pneumokoket kanë edhe përbërës të tjerë të rëndësishëm nga ana mjekësore. Muri qelizor i pneumokokeve është gjashtë shtresor dhe i ndërtuar nga peptidoglikani me acid teikoik i cili lidhet tek çdo i treti acid N-acetilmuramik. Acidet lipoteikoike janë kimikisht të ngjashëm me acidet teikoike por për dallim janë të lidhura në membranën qelizore të qelizës. Si acidi teikoik ashtu edhe acidi ...

Trimetoprim

Felmingham D, Reinert RR, Hirakata Y, Rodloff A: Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin. J Antimicrob Chemother. 2002 Sep;50 Suppl S1:25-37. PMID 12239226 ...

Streptococcus suis | Article about Streptococcus suis by The Free Dictionary

any of a group of gram-positive bacteria, genus Streptococcus, some of which cause disease. Streptococci are spherical and ... Looking for Streptococcus suis? Find out information about Streptococcus suis. ... divide by fission, but they... Explanation of Streptococcus suis ... It can also cause meningitis and pneumonia. The S. pneumoniae ... Vaccination against pneumococcal pneumonia is recommended for very young children and older persons; the vaccine inoculates ...

encyclopedia2.thefreedictionary.com

Emergence of parapneumonic empyema in the USA | Thorax

Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. N Engl J Med 2006;354: ... meningitis or empyema and a pneumonia code in another diagnosis field.15 19 Discharge diagnosis and procedure codes, including ... Changing epidemiology of pneumococcal meningitis after the introduction of pneumococcal conjugate vaccine in the United States ... Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time- ...

thorax.bmj.com

Synflorix (pneumococcal vaccine)

These bacteria are responsible for causing invasive diseases such as pneumonia, blood poisoning and meningitis. The vaccine ... Synflorix is a pneumococcal vaccine that contains extracts from 10 of the most common types of Streptococcus pneumoniae ... Synflorix is a pneumococcal vaccine that contains extracts from 10 of the most common types of Streptococcus pneumoniae ... Synflorix is a pneumococcal vaccine that contains extracts from 10 of the most common types of Streptococcus pneumoniae ...

netdoctor.co.uk

WHO | Pneumococcal Disease

... pneumoniae provide serotype-specific protection against pneumococcal infections. Pneumococcal vaccines are designed to cover ... Serious pneumococcal infections include pneumonia, meningitis and febrile bacteraemia; otitis media, sinusitis and bronchitis ... it is estimated that about one million children die of pneumococcal disease every year. Streptococcus pneumoniae is an ... Pneumococcal (conjugate) vaccines are prequalified for procurement by UN organization.. * Vaccine quality-prequalified vaccines ...

who.int

Streptococcus Laboratory: Group A Streptococcus | CDC

... pneumococcal) disease, including antibiotics, resources and protocols, the global pneumococcal strain bank, and GPS project. ... Streptococcus pneumoniae (pneumococcal) disease can range from ear and sinus infections to pneumonia, meningitis, and ... Vaccines are available to prevent pneumococcal disease in children and adults.. lab icon ... Streptococcus Laboratory Home * Streptococcus pyogenes (group A streptococci) ...

cdc.gov

CDC Global Health - Immunization - New and Underused Vaccines

Streptococcus pneumoniae is the bacterium responsible for pneumococcal disease, a leading cause of childhood pneumonia, ... Learn about the Meningitis Vaccine Projectexternal icon *Read the 2011 WHO Position Paper on meningococcal vaccines pdf icon[ ... vaccine, Haemophilus influenzae type b (Hib) vaccine, pneumococcal conjugate vaccine (PCV), rotavirus (RV) vaccine, and rubella ... such as cholera vaccine, human papillomavirus (HPV) vaccine, meningococcal vaccine, yellow fever vaccine, and typhoid vaccine ...

cdc.gov

Effect of 10-Valent Pneumococcal Vaccine on Pneumonia among Children, Brazil - Volume 19, Number 4-April 2013 - Emerging...

To assess the vaccines effectiveness for preventing pneumonia, we analyzed rates of hospitalization among children 2-24 months ... In 2010, Brazil introduced a 10-valent pneumococcal conjugate vaccine (PCV10) to its National Immunization Program. ... Of the 197,975 hospitalizations analyzed, 30% were for pneumonia. Significant declines in hospitalizations for pneumonia were ... of age who had pneumonia from all causes from January 2005 through August 2011. We used data from the National Hospitalization ...

wwwnc.cdc.gov

Streptococcus | Encyclopedia.com

... genus Streptococcus, some of which cause disease. Streptococci are spherical and divide by fission, but they remain attached ... streptococcus (strĕp´təkŏk´əs), any of a group of gram-positive bacteria, ... It can also cause meningitis and pneumonia. The S. pneumoniae diseases are sometimes referred to as pneumococcal diseases. The ... Vaccination against pneumococcal pneumonia is recommended for very young children and older persons; the vaccine inoculates ...

encyclopedia.com

Meningitis News, Articles and Research - Page 3

Today, Streptococcus pneumoniae and Neisseria meningitidis are the leading causes of bacterial meningitis. ... Before the 1990s, Haemophilus influenzae type b (Hib) was the leading cause of bacterial meningitis, but new vaccines being ... Meningitis is usually caused by a viral or bacterial infection. Knowing whether meningitis is caused by a virus or bacterium is ... For bacterial meningitis, it is also important to know which type of bacteria is causing the meningitis because antibiotics can ...

news-medical.net

Adults Can Protect Themselves With Pneumococcal Vaccines

Talk to your healthcare professional to make sure you are up to date on these and other recommended vaccines. ... There are two vaccines that provide protection against pneumococcal disease. ... Pneumococcal meningitis kills about 1 out of 6 who get it.. Pneumococcal disease is an infection caused by Streptococcus ... Pneumococcal pneumonia kills about 1 out of 20 who get it.. •Pneumococcal bacteremia kills about 1 out of 6 who get it.. • ...

infectioncontroltoday.com

Health Article - The Pneumococcal Vaccine - AARP

Pneumococcal Vaccination. The pneumococcal vaccine protects against infections caused by Streptococcus pneumoniae. These ... pneumonia. *meningitis. Infections can be quite serious. For example, meningitis can cause severe complications including:. * ... There are currently two pneumococcal vaccines used in the United States. PCV13. The PCV13 (pneumococcal conjugate vaccine) ... The PPSV (pneumococcal polysaccharide vaccine) protects against 23 types of bacteria. Its recommended for all adults over 65 ...

healthtools.aarp.org

New strategies needed to reduce pneumococcal meningitis rates

... vaccine have been highly effective in reducing pneumonia and other invasive infections caused by Streptococcus pneumoniae ... Pneumococcal Disease, Pneumonia, Research, Sepsis, Streptococcus pneumoniae, Throat, Vaccine ... PCV vaccines linked to emergence of new strains causing meningitis. The PCV7 and PCV13 vaccines - targeting seven and thirteen ... Pneumococcal conjugate vaccines (PCVs) have been highly effective in reducing pneumonia and other invasive infections caused by ...

news-medical.net

Outbreak of Pneumonia in the Setting of Fatal Pneumococcal Meningitis among US Army Trainees: Potential Role of Chlamydia...

Although the etiology of the outbreak remains unclear, the identification of both S. pneumoniae and C. pneumoniae among ... Among Alpha and Hotel Company trainees, the average weekly attack rates of radiologically-confirmed pneumonia were 1.4% and 1.2 ... incidence of pneumonia in the outbreak battalion and should be considered as possible etiologies in outbreaks of pneumonia in ... Chlamydia pneumoniae was identified from 31% of specimens collected from Alpha Company trainees with respiratory symptoms. ...

bmcinfectdis.biomedcentral.com

Clinical Catch-up from Last Week: May 5-10 | BioSpace

Pneumococcal disease is caused by Streptococcus pneumoniae, and includes non-invasive illnesses like pneumonia, sinusitis, and ... announced that its investigational 15-valent pneumococcal conjugate vaccine was "noninferior" to a currently available 13- ... It also causes invasive diseases such as bacteremia, bacteremic pneumonia, and meningitis. ... valent pneumococcal conjugate vaccine in healthy babies 6 to 12 weeks of age. Phase II study, called V114-008, met its primary ...

biospace.com

There's something we can do to ease the burden of an ageing population | World Economic Forum

Finally, there is pneumococcal disease, a bacterial infection caused by Streptococcus pneumoniae, which can cause pneumonia, ... Two main types of pneumococcal vaccine available for older adults - the 23-valent pneumococcal polysaccharide vaccine (PPV23) ... In the US alone, pneumococcal pneumonia, bloodstream infections, and meningitis kill tens of thousands of people each year, ... Another vaccine, called Td, protects against tetanus and diphtheria, but not pertussis. A Td booster should be given every ten ...

weforum.org

Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infection - Full Text...

Streptococcus pneumoniae. Conjugate vaccine. Additional relevant MeSH terms: Pneumonia. Meningitis. Pneumococcal Infections. ... Pneumonia Meningitis Invasive Pneumococcal Disease HIV Biological: 7-valent pneumococcal conjugate vaccine (Prevnar) Phase 4 ... Vaccines. Immunoglobulins. Antibodies. Heptavalent Pneumococcal Conjugate Vaccine. Immunologic Factors. Physiological Effects ... We measured pneumococcal capsular specific immunoglobulin responses to 7-valent conjugate vaccine in both lung fluid and serum ...

clinicaltrials.gov

Pneumococcal vaccine for adults and children over two years

... such as pneumonia, blood poisoning (septicaemia) and meningitis, including when pneumococcal vaccine is recommended and ... Everything you need to know about the pneumococcal polysaccharide vaccine given to prevent diseases caused by pneumococcal ... The pneumococcal polysaccharide vaccine (PPV) contains extracts from 23 of the most common types of Streptococcus pneumoniae ... Can I have the pneumococcal vaccine with other vaccines or medicines?. You should not have this pneumococcal vaccine on the ...

netdoctor.co.uk

Pneumococcal disease | aidsmap

Pneumococcal disease is caused by a bacterium called Streptococcus pneumoniae (pneumococcus). The bacteria enter the body ... It can also cause serious pneumococcal diseases including severe bacterial pneumonia, sepsis (blood poisoning) or meningitis ( ... pneumococcal conjugate vaccine (PCV, the type of vaccine used for childhood pneumococcal vaccination) and pneumococcal ... pneumococcal disease. Disease caused by the bacterial infection Streptococcus pneumoniae. In most people, it causes relatively ...

aidsmap.com

Risk of pneumonia and pneumococcal disease in people with severe mental illness: English record linkage studies | Thorax

Streptococcus pneumoniae is the main cause of community-acquired pneumonia, bacteraemia and bacterial meningitis in adults in ... Streptococcus pneumoniae: epidemiology and risk factors, evolution of antimicrobial resistance, and impact of vaccines. Curr ... 3 pneumonia specified as S pneumoniae (J13), septicaemia due to S pneumoniae (A40.3) and pneumococcal meningitis (G00.1). ... There was no separate code for pneumococcal pneumonia in the earlier versions of ICD because pneumococcal pneumonia and lobar ...

thorax.bmj.com

List articles by category - Best Practice New Zealand

Invasive pneumococcal disease caused by Streptococcus pneumoniae can result in life-threatening pneumonia, meningitis and ... The vaccine for the 2014 influenza season is now available. This year, the vaccine has been updated with two new strains, as ... Zostavax vaccine: now fully subsidised. Zostavax is a herpes zoster (shingles) vaccine that will become fully subsidised from 1 ... The management of community acquired pneumonia. Pneumonia is a significant cause of hospitalisation and mortality among both ...

bpac.org.nz

Efficacy of vaccines against Streptococcus pneumoniae - microbewiki

It causes pneumonia along with other pneumococcal infections some of which include bacterial meningitis, sinusitis, and otitis ... The two vaccines widely used are polysaccharide vaccine (23-valent polysaccharide vaccine) and pneumococcal conjugate vaccine ( ... Current pneumococcal vaccines, Polysaccharide (23-valent) PS vaccine and conjugate vaccine (PCV-7) cover the most common and ... the role of conjugate vaccines. Vaccine 18. Pletz. MW, Maus U, Krug N, Welte T and Lode H. 2008 Pneumococcal vaccines: ...

microbewiki.kenyon.edu

Pneumococcal vaccine: MedlinePlus Medical Encyclopedia Image

... a bacterium that frequently causes meningitis and pneumonia in the elderly, and people with chronic illnesses. Pneumococcal ... Pneumococcal vaccine is an immunization against Streptococcus pneumoniae, ... Pneumococcal vaccine is an immunization against Streptococcus pneumoniae, a bacterium that frequently causes meningitis and ... pneumonia in the elderly, and people with chronic illnesses. Pneumococcal pneumonia accounts for 10% to 25% of all pneumonias. ...

medlineplus.gov

List of vaccine topics - Wikipedia

en.wikipedia.org

Pneumococcal disease | Australian Vaccination-skeptics Network Inc.

This vaccine is one of 3 vaccines now used in Australia to combat diseases that can all cause meningitis, pneumonia, ... Streptococcus pneumoniae (Pneumococcal vaccine) - 2005. While these bacteria can be linked with illnesses such as meningitis, ... pneumonia, and septicaemia (blood poisoning).. The pneumococcal conjugate vaccine is one of 3 vaccines now used in Australia to ... Vaccine decisions. The vaccine designed to protect against Streptococcus pneumoniae bacteria is known as the "pneumococcal ...

avn.org.au

Pneumonia vaccine - Childhood Vaccinations - Canada.com

Pneumonococcal vaccine can help protect your child against meningitis, bacteremic pneumonia, bacteremia, and sepsis. Learn more ... pneumonia vaccine, can help protect your child against certain diseases caused by the bacteria Streptococcus pneumoniae, ... As with other vaccines, the pneumococcal vaccine may not protect 100% of people who have the vaccine, and it may cause side ... Your pneumococcal vaccine options There are important differences between the two pneumococcal vaccines for adults available in ...

bodyandhealth.canada.com

Streptococcus pneumoniae is the most common cause of otitis media in children. (thefreedictionary.com)

The S. pneumoniae diseases are sometimes referred to as pneumococcal diseases. (thefreedictionary.com)
Group A hemolytic streptococci cause over a dozen diseases, including some pneumonias, erysipelas erysipelas , acute infection of the skin characterized by a sharply demarcated, shiny red swelling, accompanied by high fever and a feeling of general illness. (thefreedictionary.com)

Scarlet fever scarlet fever or scarlatina, an acute, communicable infection, caused by group A hemolytic streptococcal bacteria (see streptococcus) that produce an erythrogenic toxin. (thefreedictionary.com)

group B hemolytic streptococci can cause serious problems, such as septicemia and meningitis, especially in newborns. (thefreedictionary.com)

strĕp'təkŏk`əs) , any of a group of gram-positive bacteria, genus Streptococcus, some of which cause disease. (thefreedictionary.com)
Enterococci (usually harmless bacteria that inhabit the intestines) and lactococci (bacteria used in starter cultures in the production of fermented dairy products) used to be considered a part of the Streptococcus genus but are now placed in their own genera. (thefreedictionary.com)

The causative agent is the hemolytic streptococcus, which often enters the body through a break in the skin. (thefreedictionary.com)

It can also cause meningitis and pneumonia. (thefreedictionary.com)

Preventing invasive pneumococcal disease (eg pneumonia , acute middle ear infections ( otitis media ), meningitis or blood poisoning) caused by Streptococcus pneumoniae bacteria in children aged six weeks to two years. (netdoctor.co.uk)
It will not protect against other groups of pneumococcal bacteria, or other organisms that cause meningitis, septicaemia (blood poisoning) or otitis media . (netdoctor.co.uk)
Streptococcus pneumoniae is the most common cause of otitis media in children. (encyclopedia.com)
It causes pneumonia along with other pneumococcal infections some of which include bacterial meningitis, sinusitis, and otitis media . (kenyon.edu)
This so-called carriage state not only allows for efficient transmission to new hosts but also precedes the onset of pneumococcal illnesses, such as pneumonia, septicemia, otitis media, and meningitis. (asm.org)
The bacteria Streptococcus pneumoniae is responsible for pneumococcal infections causing otitis media, bacteremia, pneumonia, and meningitis. (tmrresearch.com)
It is the most common cause of bacterial pneumonia and middle ear infection (otitis media) in the U.S., and is the third most frequent cause of bacterial meningitis. (nvic.org)
Otitis media, often referred to as a middle ear infection, is commonly caused by S. pneumoniae and remains the most common pediatric infection requiring treatment by the age of 12 months. (nvic.org)
93% and consolidative pneumonia by 73%, and it was associated with a 7% decrease in otitis media and a 20% decrease in tympanostomy tube placement. (aappublications.org)
Streptococcus pneumoniae causes many clinical syndromes, depending on the site of infection (e.g., acute otitis media, pneumonia, bacteremia, or meningitis). (cdc.gov)
Occasionally, however, it can invade locally to cause mucosal infections including sinusitis, otitis media or pneumonia. (medworm.com)
The bacterium can bring about different types of infections which include lung infections/inflammation (pneumonia), meningitis (inflammation of the membrane surrounding the spinal cord or brain), sepsis (an infection in the blood), sinusitis (infection of the sinuses) and otitis media (middle ear infection). (myhealth.gov.my)
Each year in the United States, pneumococcal disease accounts for an estimated 3,000 cases of meningitis, 50,000 cases of bacteremia, 500,000 cases of pneumonia, and 7 million cases of otitis media (1-4). (cdc.gov)
Worldwide, the bacterium also causes infections of the brain (meningitis), blood (sepsis), and middle ear (otitis media) and each year kills about 1 million children younger than 5 years of age. (fiercebiotech.com)
2 SPN remains a concern for US practitioners, causing both IPD (eg, meningitis, pneumonia, and bacteremia) and noninvasive disease (eg, acute otitis media [AOM] and sinusitis). (aappublications.org)

Recommendations to assure the quality, safety and efficacy of pneumococcal conjugate vaccines, Annex 3, Technical Report Series 977, 2009. (who.int)
Pneumococcal (conjugate) vaccines are prequalified for procurement by UN organization. (who.int)
Fifteen years after pneumococcal conjugate vaccines' first introduction globally in 2000, five of the highest pneumonia burden countries (India, Indonesia, Chad, China and Somalia) were still not using the vaccine in their routine immunization programs. (ip-watch.org)
The previous vaccine contained unconjugated polysaccharide antigens, which fail to elicit a protective immune response in infants and young children because these individuals respond poorly to T-independent antigens.16 Conjugate vaccines are immunogenic even in younger children because they change the T-independent response to a Tdependent immune response. (healio.com)
It is the first to demonstrate the real-life impact of pneumococcal conjugate vaccines (PCV) in a low-income country. (lshtm.ac.uk)
The Global Leadership Award is given annually by PACE to recognize an individual, organization or country that has championed pneumococcal disease prevention and made a significant contribution towards policies that advance the introduction of pneumococcal conjugate vaccines. (wikipedia.org)
Over the past few years, several pharmaceutical and biopharmaceuticals have enrolled themselves in evaluating candidates of developing pneumococcal conjugate vaccines. (tmrresearch.com)
So kids were unprotected until 2000, when drug giant Pfizer brought to market the first of the so-called pneumococcal conjugate vaccines, which do work in kids. (huffingtonpost.ca)
First let me tell you a little about pneumococcal conjugate vaccines and pneumococcal disease. (cdc.gov)
Pneumococcal conjugate vaccines are relatively new type of vaccine that has been shown to be highly effective at preventing disease and in stopping people from acquiring the bacteria in their noses and throats. (cdc.gov)
Pneumococcal conjugate vaccines are now used in infant vaccination programs in most countries around the world. (cdc.gov)
Vaccination with pneumococcal conjugate vaccines (PCVs) disrupts the pneumococcal population. (asm.org)

Pneumococcal disease can cause severe infections of the lungs (pneumonia), bloodstream (bacteremia), and lining of the brain and spinal cord (meningitis). (infectioncontroltoday.com)
Both vaccines provide protection against illnesses like meningitis and bacteremia. (infectioncontroltoday.com)
Pneumococcal bacteremia kills about 1 out of 6 who get it. (infectioncontroltoday.com)
When the bacteria spread into other parts of the body, it can lead to severe health problems such pneumonia, bacteremia, and meningitis. (infectioncontroltoday.com)
You may be at higher risk than you think from bacteria that can lead to pneumonia, bacteremia, and meningitis. (canada.com)
Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. (science20.com)
For example, pneumococcal bacteria can invade the bloodstream, causing bacteremia, and the tissues and fluids surrounding the brain and spinal cord, causing meningitis. (health.mil)
Bacteremia is a type of invasive pneumococcal disease that infects the blood. (health.mil)
Confirmation of their expression in vivo would not only verify the contribution of these genes to pathogenesis but would also elucidate their contribution to discrete forms of disease (e.g., genes expressed during pneumonia versus those in the blood during bacteremia). (asm.org)
In 2002, the National Advisory Committee on Immunization estimated that annually in Canada invasive disease in children younger than five caused 65 cases of meningitis, 700 cases of bacteremia (blood infection) and 9,000 cases of pneumonia that didn't require hospitalization. (huffingtonpost.ca)
The annual incidence of all-cause bacteremia, primary pneumococcal bacteremia, bacteremic pneumonia, peritonitis, and meningitis also decreased significantly during the study period (P (nih.gov)
The focus of this report is the prevention of invasive pneumococcal disease (i.e., bacteremia, meningitis, or infection of other normally sterile sites) through the use of pneumococcal polysaccharide vaccine. (cdc.gov)
Practitioners likely see at least 1 child per week for whom SPN bacteremia, pneumonia, or meningitis is a concern. (aappublications.org)
But occult bacteremia has nearly disappeared and meningitis is less frequent. (aappublications.org)
Roughly 25-30% of adult patients with pneumococcal pneumonia also develop pneumococcal bacteremia, which has a case-fatality rate of about 20% (may be as high as 60% among the elderly). (vaccinesafety.edu)
However, Strep pneumo bacteria can cause many more significant illnesses than just pneumonia, such as bacteremia (infection of the blood) or meningitis (infection of tissue around the brain). (unitypoint.org)
All pneumococcal meningitis episodes in children aged 5 years and younger, from 2004 to 2016, were extracted from the nationwide bacteremia and meningitis surveillance database. (eurosurveillance.org)

Children whose immune system is underactive, for example due to a genetic defect, HIV infection , or treatment with medicines that suppress the immune system, such as chemotherapy , high doses of corticosteroids, or immunosuppressants (eg to prevent transplant rejection), may not produce an adequate immune response to this vaccine. (netdoctor.co.uk)
Furthermore, the vaccine protects against both systemic and mucosal infection and prevents nasopharyngeal colonization, thereby reducing transmission in the community. (who.int)
The vaccine that prevents infection from human papillomavirus (HPV) is nothing short of a medical marvel. (news-medical.net)
University of Alabama at Birmingham researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero - already licensed to prevent meningitis - in protecting vulnerable populations from infection with the bacteria that causes gonorrhea. (news-medical.net)
Bacterial meningitis is infection of the brain and spinal cord membranes: it is difficult to treat, often fatal, and causes lasting complications in survivors. (news-medical.net)
If you experience the possible symptoms of bacterial meningitis, the most serious type of pneumococcal infection, dial 999 and ask for an ambulance. (aidsmap.com)
Disease caused by the bacterial infection Streptococcus pneumoniae . (aidsmap.com)
Group B streptococci are a common cause of infection in babies, pregnant women, the elderly, and immunologically compromised adults. (encyclopedia.com)
Vaccines work by giving the organism immunity against infection by a particular pathogen. (kenyon.edu)
The most severe infections, bacteraemia (a blood stream infection) and meningitis (inflammation of the membranes enclosing the brain), are a leading cause of life-threatening illnesses in Australia - particularly among children under two years of age and elderly people. (avn.org.au)
As well as meningitis and bacteraemia, pneumococcal disease can cause pneumonia (lung infection), septicaemia (blood poisoning), and middle ear and sinus infections. (avn.org.au)
Vaccination can substantially reduce the risk of infection with pneumococcal disease, particularly in young children. (avn.org.au)
You cannot get pneumonia or any other kind of pneumococcal infection from the vaccine since it is made from dead bacteria. (breastcancer.org)
However, pneumonia and associated complications, including a lung infection called empyema, increased in older children, the study found. (chop.edu)
While we aren't sure why we are seeing higher rates of pneumonia hospitalizations in older children, we think the decrease in infection rates in younger children is due to the vaccine. (chop.edu)
The vaccine, known as PCV7, is administered to infants to prevent infection with the Streptococcus pneumoniae bacteria, the leading bacterial cause of pneumonia. (chop.edu)
Before routine use of pneumococcal conjugate vaccine, infections caused more than 700 cases of meningitis, 13,000 blood infections and about 5 million ear infections each year in the U.S. The infection also contributed to about 200 deaths each year, according to the Centers for Disease Control and Prevention. (chop.edu)
Acute bacterial meningitis is the most life-threatening form of the disease, typically causing a rapidly developing infection that can lead to death within hours to days without immediate, appropriate treatment. (symptomfind.com)
Anyone can develop meningococcal meningitis but the infection is most common among babies younger than 12 months old, and adolescents and young adults age 16 to 21. (symptomfind.com)
Meningitis is an infection of the meninges, the membranes that cover the brain and spinal cord. (medicalnewstoday.com)
The incidence of severe pneumococcal infection, including meningitis, has decreased significantly since the introduction of the pneumococcal vaccine. (medicalnewstoday.com)
Pneumococcal meningitis symptoms start suddenly, usually within 3 days of infection with the bacteria. (medicalnewstoday.com)
Pneumonia is infection of one or both lungs. (medindia.net)
Bacteria like Streptococcus pneumoniae, Staphylococcus aureus, or Haemophilus influenzae can cause a secondary infection over the first viral one. (medindia.net)
Pneumonia can be contracted as a secondary infection by a patient who is already in the hospital being treated for another illness ( Hospital - acquired pneumonia (HAP)) . (medindia.net)
The risk of contracting a pneumococcal infection is the greatest during the first two years of life. (medical-wiki.com)
This reduces the odds of you falling ill from an infection traced to Streptococcus pneumoniae bacteria. (medical-wiki.com)
The discovery will lead to a dramatic shift in our understanding of how the body's immune system responds to infection caused by Streptococcus pneumoniae and pave the way for more effective vaccines. (redorbit.com)
across Europe, pneumococcal infection is responsible for considerable morbidity and mortality, particularly in the very young and the elderly, groups whose members respond poorly to non-conjugated vaccines. (nih.gov)
Haemophilus influenzae type B. This is a bacterial infection that leads to serious conditions such as meningitis, pneumonia, and epiglottitis. (rochester.edu)
This is a serious lung infection caused by the bacteria Streptococcus pneumoniae. (rochester.edu)
Pneumonia is an infection of the lungs, usually manifested by fever, productive cough, and shortness of breath. (jewishjournal.com)
Individuals with HIV infection, who may be safely immunised with meningococcal polysaccharide vaccines. (bpac.org.nz)
Derrick Crook, Professor of Microbiology at the University of Oxford and Infection Control Doctor at the Oxford University Hospitals NHS Trust, says: "Childhood vaccines are very effective at reducing disease and death at a stage in our lives when we are susceptible to serious infections. (healthcanal.com)
2 However, when pneumococcal bacteria cause invasive infection, serious complications can lead to inflammation of the brain, blood infections, pneumonia and death. (nvic.org)
Symptoms of pneumococcal infection include sudden onset of fever and fatigue, sneezing and cough with mucus and shortness of breath. (nvic.org)
Pneumococcal pneumonia, the most common infection caused by S. pneumoniae in adults, is estimated to cause over 400,000 hospitalizations each year in the United States. (nvic.org)
Children with functional or anatomic asplenia (including sickle cell disease [SCD]) and children with human immunodeficiency virus infection have pneumococcal infection rates 20- to 100-fold higher than those of healthy children during the first 5 years of life. (aappublications.org)
Outbreaks of pneumococcal infection have occurred with increased frequency in children attending out-of-home care. (aappublications.org)
Of children younger than 5 years old who get pneumococcal meningitis, about 1 out of 15 dies of the infection and others may have long-term problems, such as hearing loss or developmental delay. (health.mil)
Pneumonia is an infection of the lungs that can cause mild to severe illness in people of all ages. (health.mil)
Complications of pneumococcal pneumonia include infection of the space between membranes that surround the lungs and chest cavity (empyema), inflammation of the sac surrounding the heart (pericarditis), and blockage of the airway that allows air into the lungs (endobronchial obstruction), with lung collapse (atelectasis) and collection of pus (abscess) in the lungs. (health.mil)
Once in the bloodstream, infection may result in septicemia or meningitis, both of which have high mortality despite accepted antibiotic therapy ( 28 ). (asm.org)
therefore, neither vaccine cannot cause a pneumococcal infection. (symptomfind.com)
CDC reports that one out of 20 people who contract pneumococcal pneumonia die of the infection. (symptomfind.com)
The vaccine cannot cause infection by the influenza virus. (uspharmacist.com)
however, if an individual is infected by a strain that is different from but related to those in the vaccine, the antibodies that were created will attempt to fight the infection, thus making the disease course less severe. (uspharmacist.com)
Main outcome measures Events of interest included the first episode of bacterial (including pneumococcal) pulmonary infection (primary endpoint) and death of any cause (secondary endpoint). (bmj.com)
The efficacy of pneumococcal polysaccharide vaccine (PPV23) might be compromised by an episode of pulmonary infection in the prevaccine period or chronic respiratory failure in older patients with chronic pulmonary disease. (bmj.com)
Scarlet fever scarlet fever or scarlatina, an acute, communicable infection, caused by group A hemolytic streptococcal bacteria (see streptococcus) that produce an erythrogenic toxin. (thefreedictionary.com)
Pneumonia is an infection of the lungs. (apic.org)
BACKGROUND: Pneumococcal infection is one of the leading causes of pneumonia, meningitis and septicemia in developing countries. (ox.ac.uk)
Pneumococcal disease, a bacterial infection ( Streptococcus pneumoniae ) that can cause pneumonia, meningitis, sepsis, and other serious illnesses, was the next most costly at nearly $1.9 billion or 21 percent of the total. (njha.com)
Understanding the host genetics of the immune response in retrovirus infection models could provide insights for basic HIV vaccine discovery. (jove.com)
Invasive pneumococcal disease is a severe infection that mainly affects patients with associated comorbidity. (readbyqxmd.com)
Pneumococcal infection is caused by the bacteria Streptococcus pneumoniae (Strep pneumo), and when this bacteria gets in the lungs, it's called pneumococcal pneumonia. (unitypoint.org)
Rates of pneumococcal disease-an infection that can lead to pneumonia, meningitis, and other illnesses-dropped in young children following the introduction of a vaccine in 2000. (technologynetworks.com)
S. pneumoniae can then impact the upper respiratory tract and lead to infection in blood, lungs, the nervous system, as well as the ear. (redorbit.com)
Those who are younger than five years of age or older than 65 years of age have the greatest risk of becoming infected from pneumococcal pneumonia and those who suffer from the bacteria infection can possibly be re-infected. (redorbit.com)
HIV infection and other conditions associated with immune deficiency greatly increase the likelihood of contracting pneumococcal disease. (sanofi.com)

What are the risks of pneumococcal vaccination? (cdc.gov)
Vaccination with pneumococcal conjugate vaccine (PCV) is a public health intervention to prevent pneumococcal disease. (cdc.gov)
New research has found that rates of disease caused by the bacterium Streptococcus pneumoniae could be substantially reduced by changing our approach to vaccination. (news-medical.net)
Vaccination and HIV treatment reduce the risk of invasive pneumococcal disease. (aidsmap.com)
The expanded indication approved by the U.S. FDA is based on immune responses elicited by Prevnar 13, and there have been no controlled trials in adults demonstrating a decrease in pneumococcal pneumonia or invasive pneumococcal disease after vaccination with Prevnar 13. (fiercebiotech.com)
Pneumococcal vaccination is recommended as part of routine immunisation for people who face a high risk from pneumococcal and its complications. (avn.org.au)
While it might be routine for many to get a flu shot every year, few may be aware that there is a vaccination to help protect against pneumonia. (albertsons.com)
According to the CDC, there were approximately 50,000 deaths caused by pneumonia in 2014, and less than 65% of those 65 years and older have ever received their pneumococcal vaccination. (albertsons.com)
This eight-year study used robust population surveillance methods before and after introduction of two PCVs to measure the impact of routine infant vaccination with these vaccines. (lshtm.ac.uk)
citation needed] It was announced in February 2006 that the UK government would introduce vaccination with the conjugate vaccine in children aged 2, 4 and 13 months. (wikipedia.org)
Recent changes to the immunisation schedule include a new pneumococcal vaccine for infants, introduction of the High Risk Pneumococcal programme and the removal of the MeNZB vaccination programme from the schedule. (bpac.org.nz)
Pneumococcal infections are thought to kill approximately a million young children worldwide each year, although the success of vaccination programmes has led to a dramatic fall in the number of cases in countries such as the UK and the USA. (healthcanal.com)
The childhood vaccination program may have such positive indirect effects on adult invasive pneumococcal disease that the rationale for vaccinating adults is much less strong. (huffingtonpost.ca)
The American Academy of Pediatrics recommends pneumococcal vaccination for all children, concluding that it is both safe and effective for infants and older children. (symptomfind.com)
Twenty-five healthy adults were immunized once with a 23-valent pneumococcal vaccine (PNU-IMMUNE 23) from Lederle Laboratories (Pearl River, N.Y.). Serum samples were collected before and 1 month after vaccination and were stored frozen at −20°C until analysis. (asm.org)
This report contains updated information regarding a) antimicrobial resistance among pneumococci, b) vaccine effectiveness and cost-effectiveness, c) indications for vaccination, d) guidelines for revaccination, e) strategies for improving delivery of vaccine, and f) development of pneumococcal conjugate vaccine. (cdc.gov)
We assessed the impact and cost-effectiveness of vaccination with 23-valent pneumococcal polysaccharide vaccine (PPV23) or 13-valent PCV (PCV13) among all those aged 60, 65 or 70 and/or in combination with replacing PCV10 with PCV13 in the infant vaccination programme. (readbyqxmd.com)
There is no seasonality associated with pneumococcal vaccination either, so this vaccine is available any time of the year," Dr. Jenkins says. (unitypoint.org)
Even if adults received the vaccine as a baby, they will still need to receive additional vaccination, if they have one of the high-risk factors above or once they turn 65 years old. (unitypoint.org)
Talk with your doctor to see if you need vaccination against pneumococcal disease. (unitypoint.org)
The study follows how the population of pneumococcal bacteria changed following the introduction of the 'Prevnar' conjugate polysaccharide vaccine, which substantially reduced rates of pneumococcal disease across the U.S. The work demonstrates that the technology could be used in the future to monitor the effectiveness of vaccination or antibiotic use against different species of bacterial pathogens, and for characterizing new and emerging threats. (technologynetworks.com)

There are two vaccines used in the United States to help prevent pneumococcal disease: PCV13 and PPSV23. (cdc.gov)
The pneumococcal conjugate vaccine (PCV13 or Prevnar 13®) protects against 13 types of pneumococcal bacteria. (cdc.gov)
Adults 65 years or older also can discuss and decide, with their vaccine provider, to receive PCV13. (cdc.gov)
PCV13 also provides protection against pneumonia. (infectioncontroltoday.com)
Anyone who has ever had a life-threatening allergic reaction to a dose of the vaccine, to an earlier pneumococcal vaccine called PCV7 (or Prevnar), or to any vaccine containing diphtheria toxoid (for example, DTaP), should not get PCV13. (infectioncontroltoday.com)
Anyone with a severe allergy to any component of PCV13 should not get the vaccine. (infectioncontroltoday.com)
When both vaccines are recommended, you should receive a dose of PCV13 first, followed by a dose of PPSV23 at another visit. (infectioncontroltoday.com)
The PCV13 (pneumococcal conjugate vaccine) protects against 13 types of pneumococcal bacteria. (aarp.org)
Children who began immunization with the older PCV7 vaccine can continue the series using PCV13. (aarp.org)
There are two types of pneumococcal vaccines: pneumococcal conjugate vaccine (PCV13) and pneumococcal polysaccharide vaccine (PPSV23). (breastcancer.org)
Pneumococcal immunization: PCV13 (1 dose=0.5ml, intra-muscular) will be administrated during the same inclusion visit. (clinicaltrials.gov)
A second blood sampling will be scheduled 2 months (minimum 1, maximum 4) after PCV13 administration and will to assess vaccine response to PCV13. (clinicaltrials.gov)
Ask the Experts: Pneumococcal Vaccines (PCV13 and PPSV23). (albertsons.com)
The 13-valent pneumococcal conjugate vaccine (PCV13) licensure was conducted in order to analyze the impact of PCV13 introduction for children on adult IPD. (plos.org)
The newer PCV13 vaccine (13-valent pneumococcal conjugate vaccine), known by the brand name Prevnar 13, protects against bacterial pneumonia and other invasive pneumococcal illnesses in children, but the efficacy and most effective dosage in adults is unknown. (rxpgnews.com)
Earlier studies suggest that PCV13 may not induce as strong an immune response in older adults who previously received the PPSV23 vaccine within the past 5 years as in those who have not. (rxpgnews.com)
The first group, 294 participants who have never been vaccinated with the PPSV23 vaccine, will receive a single 0.5 milliliter (mL) injection of the PCV13 vaccine. (rxpgnews.com)
The second group, 588 participants who were vaccinated with the PPSV23 vaccine three to seven years before study enrollment, will be randomized to receive one 0.5 mL injection of the PCV13 vaccine or 1.0 mL of the PCV13 vaccine administered as two 0.5 mL injections, one in each arm. (rxpgnews.com)
The researchers will also evaluate whether the larger, 1.0 mL, dose of PCV13 is more immunogenic than the 0.5 mL dose in participants who were previously vaccinated with the PPSV23 vaccine. (rxpgnews.com)
It's called Prevnar 13 (PCV13, 13-valent pneumococcal conjugate vaccine). (jewishjournal.com)
There are two types of pneumococcal vaccines licensed for use in the U.S. today: Pneumovax 23, a pneumococcal polysaccharide vaccine (PPSV23) manufactured by Merck, and Prevnar 13, a pneumococcal conjugate vaccine (PCV13) manufactured by Wyeth (Pfizer) pharmaceuticals. (nvic.org)
The CDC recommends four doses of pneumococcal conjugate vaccine (PCV13) for infants and children, with a dose given at 2, 4, 6 and between 12 and 18 months of age. (nvic.org)
Children between 2 and 18 years who are at a higher risk of invasive pneumococcal disease are also recommended to receive one dose of PPSV23 at least 8 weeks following the most recent dose of PCV13. (nvic.org)
The pneumococcal conjugate vaccine (PCV13 or Prevnar 13®) protects against the 13 types of pneumococcal bacteria that cause most of the severe illness in children and adults. (health.mil)
Bacterial proteins in the PCV13 vaccine are attached to a carrier, known as a conjugate, which helps stimulate the immune system to produce protective antibodies. (symptomfind.com)
Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE ), announced today that it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMEA) for approval to market its investigational 13-valent pneumococcal conjugate vaccine (PCV13) for infants and young children. (webwire.com)
Both Prevenar (also known as PCV7) and PCV13 use CRM197 an immunological carrier protein with a 20-year history of use in pediatric vaccines. (webwire.com)
The results also showed that the safety and tolerability of PCV13 and Prevenar are comparable, and that PCV13 can be administered with other commonly used pediatric vaccines. (webwire.com)
Adults over age 65 need to get two vaccines, the pneumococcal 13 (PCV13) and the pneumovax 23 (PPSV23) one year apart. (unitypoint.org)
Recently, children have had the newer PCV13 vaccine, otherwise known as Prevnar 13. (redorbit.com)
One group will have never been vaccinated with the PPSV23 vaccine, but will then be given the PCV13 vaccine. (redorbit.com)
The other group will have participants who received the PPSV23 vaccine three to seven years before the start of the study, and will also randomly be given either the PCV13 vaccine as 0.5 mL injection or the PCV13 vaccine as two 0.5 mL injections in each arm. (redorbit.com)
Pneumococcal meningitis incidence rates declined non-significantly by 17%, comparing PCV13 and pre-PCV periods. (eurosurveillance.org)
The PCV13 vaccine provides immunity from 13 different types of pneumococcal bacteria. (schmidtlaw.com)
Most health experts recommend the PCV13 vaccine as a routine childhood immunization, at ages 2 months, 4 months, 6 months, and 12-15 months. (schmidtlaw.com)

Vaccines contain extracts or inactivated forms of bacteria or viruses that cause disease. (netdoctor.co.uk)
Streptococcus pneumoniae (pneumococcal) disease can range from ear and sinus infections to pneumonia, meningitis, and bloodstream infections. (cdc.gov)
Vaccines are available to prevent pneumococcal disease in children and adults. (cdc.gov)
it is estimated that about one million children die of pneumococcal disease every year. (who.int)
Pneumococcal disease in adults can range from mild to serious, and can sometimes be deadly. (cdc.gov)
Two vaccines provide protection against this disease. (cdc.gov)
What is pneumococcal disease? (cdc.gov)
What are the symptoms of pneumococcal disease? (cdc.gov)
Doctors can treat pneumococcal disease with antibiotics. (cdc.gov)
How does pneumococcal disease serious? (cdc.gov)
Pneumococcal disease is most often mild. (cdc.gov)
However, Pneumococcal bacteria spread from person to person it can cause serious disease and lifelong disabilities through coughing, sneezing, and close contact. (cdc.gov)
Which adults are at increased risk for pneumococcal disease? (cdc.gov)
Which vaccines help prevent pneumococcal disease in adults? (cdc.gov)
In addition, getting an influenza (flu) vaccine every year can help because having flu can increase your chances of getting pneumococcal disease. (cdc.gov)
A new study highlights how air pollution affects the airways making the body susceptible to developing the pneumococcal disease. (news-medical.net)
There are two vaccines that provide protection against pneumococcal disease. (infectioncontroltoday.com)
Each year in the United States, pneumococcal disease kills thousands of adults, including 18,000 adults 65 years or older. (infectioncontroltoday.com)
Thousands more end up in the hospital because of pneumococcal disease. (infectioncontroltoday.com)
The best way to prevent pneumococcal disease is by getting vaccinated. (infectioncontroltoday.com)
Pneumococcal disease can lead to disabilities like deafness, brain damage, or loss of arms or legs. (infectioncontroltoday.com)
Pneumococcal disease is treated with antibiotics. (aidsmap.com)
There are more than 90 pneumococcal types that can cause disease in humans. (aidsmap.com)
Compared to the general population, people living with HIV are more likely to develop severe forms of pneumococcal disease, whatever the health of their immune system. (aidsmap.com)
These are often called 'invasive' pneumococcal disease, as they occur in a major organ or in the blood, and can lead to serious illness. (aidsmap.com)
UK research published in 2011 showed that rates of severe pneumococcal disease were between 25 and 50 times higher in adults living with HIV, depending on age. (aidsmap.com)
A low CD4 cell count is a risk factor for developing pneumococcal disease for people living with HIV, especially for people who are not taking HIV treatment . (aidsmap.com)
Taking HIV treatment reduces the risk of invasive pneumococcal disease, strengthening the immune system and making it better able to fight infections. (aidsmap.com)
Symptoms of pneumococcal disease include fever, chills and sweats, headache, cough and a general feeling of being unwell. (aidsmap.com)
Mild cases of pneumococcal disease are likely to go away after a few days, without the need for any special treatment. (aidsmap.com)
streptococcus (strĕp´təkŏk´əs) , any of a group of gram-positive bacteria, genus Streptococcus, some of which cause disease. (encyclopedia.com)
The risk of pneumococcal disease in people with mental disorders is unknown. (bmj.com)
Methods We used two datasets of linked hospital admission and death records, the Oxford Record Linkage Study and all-England linked Hospital Episode Statistics, to estimate the risk of lobar pneumonia and other pneumococcal disease (here, all collectively termed pneumococcal disease) in people hospitalised with schizophrenia, bipolar disorder, depression or anxiety. (bmj.com)
We compared rates of pneumococcal disease in each cohort with rates in a comparison cohort of people without a record of hospitalisation for these psychiatric disorders. (bmj.com)
Findings The risk of pneumococcal disease in each psychiatric group was significantly high in both datasets. (bmj.com)
In the English national dataset (spanning 1999-2011), the risk of pneumococcal disease in people hospitalised with schizophrenia, bipolar disorder, depression or anxiety was, respectively, 2.3 (95% CI 2.2 to 2.4), 2.3 (2.2 to 2.3), 2.1 (2.0 to 2.1) and 2.2 (2.1 to 2.2). (bmj.com)
Is severe mental illness a risk factor for pneumococcal disease? (bmj.com)
People with severe mental illness are at higher risk than others of pneumococcal disease, but are not yet recognised as a high-risk group in current immunisation policies. (bmj.com)
This is a new risk factor for pneumococcal disease. (bmj.com)
Pneumococcal disease is the term used to describe infections caused by the bacterium Streptococcus pneumoniae when the pathogen is detected in normally sterile body fluids. (bmj.com)
Current immunisation guidelines in the UK and the USA are designed to protect those at elevated risk of pneumococcal disease, including infants, adults aged 65 and over, and people with selected medical conditions. (bmj.com)
We used routine datasets of hospital admission and mortality data, enhanced by record linkage, to study the risk of pneumococcal disease in people admitted to hospital for schizophrenia, bipolar disorder, depression or anxiety. (bmj.com)
Influenza is another vaccine-preventable disease. (weforum.org)
Vaccines contain a weakened or dead derivative of the pathogen and in its altered state, vaccine pathogens, are typically safe and unable to cause disease 15 . (kenyon.edu)
Current pneumococcal vaccines target the polysaccharide capsule because immunity after pneumococcal disease is directed against the capsular serotype of the S. pneumoniae bacteria involved . (kenyon.edu)
A vaccine is a biological preparation that improves immunity to a particular disease . (wikipedia.org)
A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins. (wikipedia.org)
Pneumococcal disease, including pneumonia, in adults 50 years and older represents a significant personal and societal health burden in the United States. (fiercebiotech.com)
Pneumococcal disease (PD) is a leading public health issue in adults 50 years of age and older, a population rapidly increasing in the United States. (fiercebiotech.com)
Clearly, there remains a high incidence of pneumococcal pneumonia in this adult population," said Emilio Emini, Ph.D., chief scientific officer, Vaccine Research, Pfizer Inc. "Prevnar 13 was licensed for adults 50 years and older by the FDA under an accelerated approval pathway because of its potential to help address this significant disease burden. (fiercebiotech.com)
Prevnar 13 was first approved by the U.S. FDA in February 2010 for the prevention of invasive pneumococcal disease in infants and young children from 6 weeks through 5 years of age. (fiercebiotech.com)
Pneumococcal disease refers to a wide range of infections caused by the bacterium Streptococcus pneumoniae . (avn.org.au)
Pneumococcal disease is defined as any illness caused by the bacterium Streptococcus pneumoniae . (avn.org.au)
While these bacteria can be linked with illnesses such as meningitis, septicaemia and pneumonia, over 90% of us will play host to the range of bacteria that can cause these conditions without ever showing symptoms of any disease. (avn.org.au)
There is no long-term data yet for determining success or failure of the vaccine for pneumococcal disease in Australia, in terms of the target illnesses. (avn.org.au)
After PCV7 was licensed, the rate of invasive pneumococcal disease such as meningitis and blood infections decreased by 76 percent among children 5 years and younger, according to the CDC. (chop.edu)
Pneumococcal disease kills approximately 18,000 adults aged 65 years and older in the United States every year. (albertsons.com)
There is a specific type of pneumonia shot recommended by the Centers for Disease Control and Prevention (CDC) for young adults with diabetes, heart disease, COPD, asthma or smokers. (albertsons.com)
Dr Abby Colson of the University of Strathclyde (Scotland) and AMR research group, the Center for Disease Dynamics, Economics and Policy (CDDEP), says that universal coverage of PCV could reduce antibiotic use for pneumococcal disease by 47 percent. (ip-watch.org)
Together, these vaccines have averted child deaths by preventing pneumococcal disease and, importantly, the need for antibiotics. (ip-watch.org)
Anyone age 2 through 64 with a health condition that increases their risk for pneumococcal disease. (symptomfind.com)
PnuBioVax is composed of a well characterised mixture of proteins and, in contrast to other products on the market, delivers protection against Pneumococcal disease that is independent of serotype. (uk-cpi.com)
In 1999, the estimated incidence of invasive pneumococcal disease in the United States was 163 cases per 100,000 population among children younger than 12 months and 205 cases per 100,000 population among those 12 to 23 months. (healio.com)
Although the highest rates of invasive pneumococcal disease occur in young children, especially those younger than 2 years, no pneumococcal vaccine was available for this age group until recently. (healio.com)
Reducing the rate of pneumococcal disease is crucial, both to save lives and reduce a substantial economic burden on the health system and families. (lshtm.ac.uk)
The data generated will facilitate the introduction and maintenance of PCVs in other countries in Africa, where the rate of pneumococcal disease is ten times higher than in developed countries. (lshtm.ac.uk)
A total of 320 cases of invasive pneumococcal disease were identified during follow-up period. (lshtm.ac.uk)
The results should reassure developing countries that spending money on PCV, and delivering the vaccine with reasonable coverage, will substantially reduce rates of pneumococcal disease. (lshtm.ac.uk)
The trial will also evaluate whether the vaccine is effective in preventing all-cause pneumonia and invasive pneumococcal disease. (science20.com)
Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. (science20.com)
According to the Centers for Disease Control and Prevention (CDC) , children with conditions affecting the spleen, such as sickle cell, HIV , or AIDS , have a much higher risk of developing pneumococcal meningitis. (medicalnewstoday.com)
When pneumonia is at its height it is bad if he had dyspnea and if sweat comes out about the neck and head, for such sweats are bad, as proceeding from the suffocation, rales, and the violence of the disease. (medindia.net)
It prevents the occurrence of pneumococcal disease caused by Streptococcus pneumoniae bacteria, which leads to bacterial meningitis, blood infections and other severe health complications in young children. (medical-wiki.com)
Moreover, the vaccine obstructs the spread of the disease which is communicable. (medical-wiki.com)
It must be noted that the pneumococcal polysaccharide vaccine does not provide protection from pneumococcal disease to persons under the age of 2. (medical-wiki.com)
Established in December 2006, The Council seeks to raise awareness among policymakers and aims to secure global commitments to prevent pneumococcal disease, a leading infectious killer of children and adults worldwide. (wikipedia.org)
PACE has hosted and participated in a number of events worldwide to help raise awareness about pneumococcal disease. (wikipedia.org)
PACE Global Leadership Award recipients include: Dr. Thomas Cherian, who has helped accelerate the surveillance of pneumonia throughout the developing world and contributed to research on the global pneumococcal disease burden. (wikipedia.org)
PACE issued a Global Call to Action on Pneumococcal Disease Prevention, urging governments to take steps to make financing available for access to pneumococcal vaccines. (wikipedia.org)
In October 2009, PACE conducted a briefing and one-on-one meetings with members of the European Parliament and European Commission to recommend action on pneumococcal disease. (wikipedia.org)
In 2008, PACE launched its Global Call to Action on Pneumococcal Disease Prevention in partnership with 114 professional medical societies, organizations and institutions from around the world. (wikipedia.org)
A prospective laboratory-based multicenter study that collected all adult invasive pneumococcal disease (IPD) episodes from 6 Spanish hospitals before (2008-2009) and after (2012-2013). (plos.org)
Streptococcus pneumoniae is a leading cause of severe disease worldwide, mainly affecting children and the elderly populations. (plos.org)
Asymptomatic colonization of the nasopharynx by Streptococcus pneumoniae precedes pneumococcal disease, yet pneumococcal colonization factors remain poorly understood. (asm.org)
More than 300,000 people in the United States are hospitalized annually for pneumonia, according to the Centers for Disease Control and Prevention. (rxpgnews.com)
For the past 30 years, the PPSV23 vaccine (23-valent pneumococcal polysaccharide vaccine), known by the brand name Pneumovax 23, has been the standard protection from invasive pneumococcal disease in adults over 65 years of age. (rxpgnews.com)
Streptococcus pneumoniae causes invasive pneumococcal disease (IPD) including meningitis and sepsis, community-acquired pneumonia (CAP), and nursing and healthcare associated pneumonia (NHCAP) in children and adults infected with the bacterium. (freepatentsonline.com)
The recommended three or four doses are between 71 and 93% effective at preventing severe pneumococcal disease. (wikipedia.org)
Under the terms of an AMC, donors make a legally binding guarantee that, if a future vaccine is developed against a particular disease, they will purchase a predetermined amount at an agreed-upon price. (wikipedia.org)
Describing the results as exciting, the researchers say it will potentially have a significant impact in the development of vaccines against pneumococcal disease. (redorbit.com)
Invasive pneumococcal disease, including pneumonia, meningitis and bacteraemia, has been linked annually to the deaths of millions of children. (nih.gov)
This vaccine has demonstrated high efficacy against invasive pneumococcal disease in clinical trials in infants and young children and is currently licensed for use in the United States and selected countries in Europe and Latin America. (nih.gov)
The advent of new conjugated pneumococcal vaccines now offers an exciting opportunity in developed countries to reduce both the current burden of disease and the threat of rising antibiotic resistance. (nih.gov)
Demand for prevention of invasive pneumococcal disease has helped shape the approaches for manufacturers. (tmrresearch.com)
children, adolescents and adults with conditions that are associated with an increased risk of invasive pneumococcal disease. (diabetesqld.org.au)
For those children, adolescents and adults at high risk of invasive pneumococcal disease or Aboriginal and Torres Strait Islander adults, a varied immunisation schedule may exist, depending on the state in which you live. (diabetesqld.org.au)
Diabetes is listed as a condition associated with an increased risk of invasive pneumococcal disease. (diabetesqld.org.au)
Although the vast majority of children with pneumonia recover, the disease is occasionally fatal. (chop.edu)
Activities like smoking can also disrupt the lining of the nose and throat and allow for pneumococcal infections and subsequent disease. (chop.edu)
The Centers for Disease Control and Prevention (CDC) estimate that 900,000 people in the U.S. contract pneumococcal pneumonia every year, and tens of thousands of them die. (jewishjournal.com)
The introduction of a conjugate pneumococcal vaccine, PCV7 (Prevenar®) will allow for the protection of infants, reducing incidence of disease in the broader community through herd immunity. (bpac.org.nz)
Following the introduction of the vaccine in the US in 2000, there was a decline of 85% in invasive pneumococcal disease incidence in young children, and a decline in invasive pneumococcal disease (IPD) in unimmunised adults from the herd immunity effects, created by vaccinating the infants. (bpac.org.nz)
Children considered at risk of pneumococcal disease may be eligible for the High-risk Pneumococcal Programme. (bpac.org.nz)
This '7-valent' vaccine was extremely effective and had a dramatic effect on reducing disease among the age groups targeted. (healthcanal.com)
Remarkably, the vaccine has also prevented transmission from young children to adults, resulting in tens of thousands fewer cases of pneumococcal disease each year. (healthcanal.com)
In research funded by the Wellcome Trust, scientists at the University of Oxford and at the Centers for Disease Control and Prevention in Atlanta studied what happened after the introduction of this vaccine in the USA. (healthcanal.com)
In the UK, the 7-valent vaccine resulted in a substantial drop in disease overall. (healthcanal.com)
5 Persons most at risk of developing invasive pneumococcal disease include immunocompromised individuals, smokers, persons with chronic cardiac, lung, or kidney disease, individuals without a spleen, and persons with cochlear implants or a cerebrospinal fluid leak. (nvic.org)
It is also approved for the prevention of invasive disease caused by S. pneumoniae in children between 6 and 17 years and for the prevention of pneumonia and invasive disease caused by S. pneumoniae in adults 18 years of age and older. (nvic.org)
Children of Native American (American Indian and Alaska Native) or African American descent also have higher rates of invasive pneumococcal disease. (aappublications.org)
The administration of antibiotics to children involved in outbreaks of pneumococcal disease has had an inconsistent effect on nasopharyngeal carriage. (aappublications.org)
Pneumococcal polysaccharide vaccines have been recommended since 1985 for children older than 2 years who are at high risk of invasive disease, but these vaccines were not recommended for younger children and infants because of poor antibody response before 2 years of age. (aappublications.org)
The decision to administer Prevenar should be based on its efficacy in preventing invasive pneumococcal disease. (newswire.ca)
According to the World Health Organization (WHO), pneumococcal disease is the leading cause of vaccine-preventable death worldwide in children younger than 5 years and is estimated to cause up to 1 million deaths worldwide in children each year. (newswire.ca)
Starting in 2000, a conjugate pneumococcal vaccine is recommended for prevention of pneumococcal disease in the pediatric population. (cdc.gov)
Here she tells us about a recent trial of a multi-dose pneumococcal disease vaccine, and why even the crazy hours are worthwhile. (mrc.ac.uk)
Pneumococcal disease ― including pneumonia and meningitis ― is predominantly caused by the Streptococcus pneumoniae bacteria. (mrc.ac.uk)
Meningitis is the most severe type of invasive pneumococcal disease. (health.mil)
Sinus and ear infections are usually mild and are much more common than the more severe forms of pneumococcal disease. (health.mil)
This information paper describes pneumococcal disease and the vaccines to prevent it. (health.mil)
Outbreaks of severe pneumococcal disease occur sporadically and can affect large numbers of individuals, although they are less frequent compared to the pre-antibiotic era.1 The responsible pathogen, Streptococcus pneumoniae, is a Gram-positive bacterium that commonly colonises the nasopharyngeal tract, especially in young children. (medworm.com)
Streptococcus pneumoniae is a leading cause of invasive bacterial disease. (asm.org)
Streptococcus pneumoniae is the primary cause of community-acquired pneumonia and a major cause of invasive bacterial disease ( 28 ). (asm.org)
Ideally, characterization of pneumococcal virulence determinants should include analysis of gene expression during invasive disease. (asm.org)
To circumvent the requirement for RNA, investigators have used differential fluorescence induction (DFI) to identify S. pneumoniae promoters that are induced during disease ( 29 ). (asm.org)
In this case, the disease agent is Streptococcus pneumoniae bacteria, a major cause of pneumonia in adults and children, and of inner ear infections in young kids. (huffingtonpost.ca)
As well, the bacteria can invade the blood, the cerebrospinal fluid, or more rarely the fluid in joints, or the lining of the lungs or heart - a development called invasive pneumococcal disease. (huffingtonpost.ca)
The newer vaccines were brought to market to protect against invasive pneumococcal disease, which can trigger meningitis and blood infections, sometimes with tragic consequences. (huffingtonpost.ca)
In children, those under five and especially those under two years of age have the highest risk of developing serious pneumococcal disease. (huffingtonpost.ca)
Before the vaccine was available, Toronto would record 30 cases of invasive pneumococcal disease per 100,000 children each year. (huffingtonpost.ca)
Once the vaccine was added to the public program in 2005, the number of cases of invasive pneumococcal disease dropped to five per 100,000 children. (huffingtonpost.ca)
For more than 20 years, rising antibiotic resistance rates have made treatment of invasive disease more difficult and have prompted the development of more inclusive vaccine products. (healio.com)
Current pneumococcal vaccines - the 23-valent polysaccharide vaccine (PPSV-23) intended for high-risk individuals older than 2 years available since the 1970s and the 7-valent conjugate vaccine (PCV7) introduced in 2000 for all infants - have proven effective in reducing rates of serious pneumococcal disease. (healio.com)
2 Children younger than 2 years have the highest age-specific attack rates of invasive pneumococcal disease (IPD), peaking between 6 and 11 months. (healio.com)
The Trend of Invasive Pneumococcal Disease (IPD) According to the U.S. Pediatric Multicenter Pneumococcal Surveillance Group Since the Introduction of the 7-Valent Pneumococcal Conjugated Vaccine in 2007. (healio.com)
Pneumovax is the brand name for the pneumococcal polysaccharide vaccine, which doctors recommend seniors and other at-risk adults get to protect themselves from the pneumococcal disease, a serious health threat that can lead to death. (thedacare.org)
Such infections are called pneumococcal disease -- they include pneumonia, meningitis and septicemia. (thedacare.org)
When you add up all these infections, pneumococcal disease is a leading cause of infections and deaths around the world, especially in infants and the elderly. (cdc.gov)
Cynthia Whitney] The surveillance system in Israel was set up by working with all the hospitals in the country--26 of them--to get them to report every time a patient was treated there who had invasive pneumococcal disease. (cdc.gov)
The authors of this report were able to look at how the amount of invasive disease changed after a new pneumococcal conjugate vaccine program began in Israel. (cdc.gov)
The authors found that rates of pneumococcal disease did drop after the new vaccine program began. (cdc.gov)
Overall, disease rates dropped by about a third, and rates among the youngest kids, the target age group for the vaccine, dropped by about 50 percent. (cdc.gov)
When it comes to disease-causing bacteria, Streptococcus pneumonia is a bad actor. (symptomfind.com)
Anyone ages 2 through 64 who has a medical condition that increases the risk for pneumococcal disease. (symptomfind.com)
Women who are at risk for pneumococcal disease and plan to become pregnant should ideally be immunized before the pregnancy. (symptomfind.com)
A new vaccine has been developed that allows bacteria to grow inside the body, only actively fighting microbes that cause disease. (labroots.com)
Health objectives set by Healthy People 2010 include increasing the proportion of noninstitutionalized adults who are appropriately vaccinated against pneumococcal disease and influenza. (uspharmacist.com)
Pneumococcal disease causes more fatalities than any other vaccine-preventable nonviral disease. (uspharmacist.com)
however, in certain high-risk groups (including patients with asplenia, diabetes, or asthma/chronic obstructive pulmonary disease) who received the vaccine previously, at least 5 years should elapse before revaccination. (uspharmacist.com)
strĕp'təkŏk`əs) , any of a group of gram-positive bacteria, genus Streptococcus, some of which cause disease. (thefreedictionary.com)
Since pneumococcal disease is a vaccine preventable disease, getting vaccinated is the best option. (myhealth.gov.my)
The pneumococcal vaccine will help stimulate our body to make antibodies against Streptococcus pneumoniae which causes the disease. (myhealth.gov.my)
7. Get a sho t - If you or your loved one is at high risk for pneumococcal disease, get vaccinated before your hospital stay. (apic.org)
The pneumococcal vaccine is recommended for all adults 65 years and older and for anyone who is 2 years and older at high risk for disease , including smokers, those with chronic illnesses or conditions that weaken the immune system, or who live in a nursing home or other long-term care facility. (apic.org)
Streptococcus pneumoniae colonizes the human upper respiratory tract, and this asymptomatic colonization is known to precede pneumococcal disease. (asm.org)
Decline in the incidence of invasive pneumococcal disease at a medical center in Taiwan, 2000-2012. (nih.gov)
This vaccine protects against invasive bacteremic disease, although existing data suggest that it is less effective in protecting against other types of pneumococcal infections. (cdc.gov)
Rates of invasive pneumococcal disease are exceptionally high among Alaskan Natives and American Indians. (cdc.gov)
The measles vaccine proved so effective that the disease was declared eliminated , first in the United States in 2000, then throughout the entire North American continent in 2015 . (njha.com)
The collaboration aims to improve the techniques used to produce effective, safe, and affordable vaccines against pneumococcal disease for children in the developing world. (fiercebiotech.com)
CBER will use its scientific expertise to develop technology for a vaccine against pneumococcal disease that is safe and effective," said Karen Midthun, M.D., acting director of the FDA's CBER. (fiercebiotech.com)
Treatment and prevention of invasive pneumococcal disease. (readbyqxmd.com)
To test the hypothesis that prescription opioid use is an independent risk factor for invasive pneumococcal disease (IPD). (readbyqxmd.com)
Excluding HIV-associated pneumococcal deaths, global estimates attribute ∼11% of all deaths in children 1 to 59 months of age to SPN disease. (aappublications.org)
NACI previously recommended 23-valent pneumococcal polysaccharide vaccines (PPV23) for use in persons ≥ 2 years of age who are at high risk of invasive pneumococcal disease (IPD), but these vaccines are poorly immunogenic in younger children. (cfpc.ca)
Today s submission is an important milestone for Wyeth and underscores the company s commitment to help protect current and future generations from serious pneumococcal disease, says Emilio Emini, Ph.D., Executive Vice President, Vaccine Research and Development, Wyeth Pharmaceuticals. (webwire.com)
Since its introduction, Prevenar has had a substantial impact on public health, dramatically reducing the rate of invasive pneumococcal disease where it is routinely used. (webwire.com)
Our investigational 13-valent pneumococcal conjugate vaccine is designed to broaden protection, with the potential to cover up to 92 percent of invasive pneumococcal disease in infants and young children worldwide. (webwire.com)
Pneumococcal disease affects both children and adults, and is a leading cause of illness and death worldwide. (webwire.com)
Due to the significant burden of pneumococcal disease and demonstrated vaccine efficacy, the World Health Organization (WHO) recommends the priority inclusion of PCV7 in national childhood immunization programs worldwide. (webwire.com)
Our investigational vaccine, Prevenar 13, builds on the scientific foundation of Prevenar and is designed to provide more comprehensive protection against pneumococcal disease," says Emilio A. Emini, Ph.D., Executive Vice President, Vaccines Research and Development, Wyeth Pharmaceuticals. (bio-medicine.org)
How Do You Get Pneumococcal Disease? (unitypoint.org)
With increasing age, the chance of dying from pneumococcal disease increases. (unitypoint.org)
Dr. Jenkins recommends everyone 65 and older be vaccinated against pneumococcal disease. (unitypoint.org)
As a part of children's regular vaccine schedule, they receive a series of shots to prevent pneumococcal disease. (unitypoint.org)
Clinical information was collected for children and adults with invasive pneumococcal disease (IPD). (ersjournals.com)
A dramatic decrease of invasive pneumococcal disease (IPD) was observed after vaccine introduction in vaccinated children and a herd immunity effect was seen in other age groups [ 22 - 24 ]. (ersjournals.com)
Pneumococcal disease is caused by a type of bacteria called Streptococcus pneumoniae, which is present in many people's noses and throats and is spread by coughing, sneezing, or other contact with respiratory secretions. (technologynetworks.com)
This small genetic alteration appears to be responsible for the large reduction in the rates of pneumococcal disease. (technologynetworks.com)
In the past, the vaccine PPSV23 vaccine, also known as Pneumovax 23, has been utilized to protect those 65 years of age and up from pneumococcal disease. (redorbit.com)
According to the U.S. Centers for Disease Control and Prevention ( CDC ), there are over 300,000 people in the country who are hospitalized due to pneumonia. (redorbit.com)
The collaboration agreement includes research & development, production, and commercialization of a preventative pneumococcal disease vaccine. (sanofi.com)
It is estimated that about 14.5 million episodes of serious pneumococcal disease occur annually, resulting in about 826,000 deaths in children aged 1-59 months. (sanofi.com)
Empiric treatment of pneumococcal meningitis includes ceftriaxone with vancomycin to overcome ceftriaxone resistant disease. (eurosurveillance.org)
80% reduction of penicillin- resistant pneumococcal meningitis and complete disappearance of ceftriaxone resistant disease. (eurosurveillance.org)
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. (eurosurveillance.org)
Bacterial meningitis is a rare but potentially fatal disease. (nih.gov)
The disease is caused by the bacterium Streptococcus pneumoniae, which also causes pneumonia, blood poisoning (septicemia), and ear and sinus infections. (nih.gov)
Those most at risk of getting this disease are children in child-care settings and children who do not have access to the vaccine. (nih.gov)
and Mycobacterium tuberculosis meningitis , a rare disease that occurs when the bacterium that causes tuberculosis attacks the meninges. (nih.gov)
Introduction: The pneumococcal vaccine is recommended for children with CRF due to their increased risk in acquiring the invasive form of the disease. (usp.br)

Adults and children over five years of age who need a pneumococcal vaccine will be given a different pneumococcal vaccine called Pneumovax II . (netdoctor.co.uk)
Streptococcus pneumoniae is the main cause of community-acquired pneumonia, bacteraemia and bacterial meningitis in adults in developed countries. (bmj.com)
Adults need to understand that some of the more common infections to which they are vulnerable are vaccine-preventable. (weforum.org)
Two subsidised seasonal influenza vaccines, Influvac Tetra (for adults and children aged three years and over) and Fluarix Tetra. (bpac.org.nz)
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) announced today that the U.S. Food and Drug Administration (FDA) has granted approval of the Company's pneumococcal conjugate vaccine Prevnar 13®* (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) as a single dose for use in adults. (fiercebiotech.com)
The FDA approval of Prevnar 13 for these adults offers the potential to contribute to the health of millions of aging Americans," said Ian Read, chairman and chief executive officer, Pfizer Inc. "This approval is representative of Pfizer's dedication to discovering and bringing to market life-changing medicines and vaccines. (fiercebiotech.com)
Pfizer is currently conducting the Community-Acquired Pneumonia Immunization Trial in Adults (CAPiTA) to fulfill requirements under the accelerated approval pathway. (fiercebiotech.com)
In addition, Pfizer has agreed, as a post-marketing commitment in connection with the approval by the U.S. FDA, to conduct a study evaluating concomitant use of Prevnar 13 and TIV (annual trivalent inactivated influenza vaccine) in adults 50 years of age and older who have been previously immunized with PPSV. (fiercebiotech.com)
As a conjugate vaccine, Prevnar 13 offers an important new option for adults 50 years and older to include as part of their preventive strategy for healthy aging. (fiercebiotech.com)
In addition to being recommended for healthy children and older adults, the pneumococcal vaccine is also recommended for people with cancer who have radiation therapy or certain chemotherapy medications. (breastcancer.org)
There are important differences between the two pneumococcal vaccines for adults available in Canada. (canada.com)
https://www.cdc.gov/vaccines/adults/rec-vac/health-conditions/diabetes.html. (albertsons.com)
14,650 children and adults were monitored for signs of pneumonia, sepsis, and meningitis during the course of the study in Basse, The Gambia, where the UK MRC has a field station. (lshtm.ac.uk)
Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced the initiation of the Community Acquired Pneumonia Immunization Trial in Adults a major study in adults of an investigational 13-valent conjugate vaccine designed to help prevent pneumococcal pneumonia -- the leading cause of bacterial pneumonia in adults. (science20.com)
The results from this trial are not intended or required for inclusion in Wyeth's currently planned regulatory filings for the use of the 13-valent pneumococcal conjugate candidate vaccine in adults. (science20.com)
The Community Acquired Pneumonia Immunization Trial in Adults is a double-blind, placebo-controlled study expected to enroll approximately 85,000 participants 65 years of age and older. (science20.com)
The investigational 13-valent vaccine being evaluated in this trial in adults uses Wyeth-pioneered conjugation technology, and is based on the science of PREVENAR(TM) (Pneumococcal Saccharide Conjugated Vaccine, Adsorbed). (science20.com)
The 13-valent pneumococcal conjugate vaccine is currently being studied in late-stage global clinical trials in both infants and adults. (science20.com)
Pneumococcal pneumonia in adults represents a significant burden, both clinically and economically," says Emilio Emini, Ph.D., Executive Vice President, Vaccine Research and Development, Wyeth Pharmaceuticals. (science20.com)
S. pneumoniae is the most common cause of bacterial meningitis in adults. (medicalnewstoday.com)
The study supported by the National Institutes of Health will compare two dosages of a pneumococcal vaccine approved for children ages 6 weeks to 5 years, and adults 50 and older. (rxpgnews.com)
In 2009, pneumonia ranked eighth among the 15 leading causes of death in the United States, with adults 55 and older accounting for the majority (92 percent) of all pneumonia-related deaths that year. (rxpgnews.com)
Children younger than 5 and adults older than 65 are most susceptible to becoming ill from pneumococcal pneumonia. (rxpgnews.com)
The polysaccharide vaccines, while effective in healthy adults, are not effective in children less than two years old or those with poor immune function. (wikipedia.org)
Though pneumococcal infections can occur at any age, persons at greatest risk include children younger than 2 years of age and adults aged 65 years or more. (nih.gov)
Pneumonia vaccines are recommended for adults and children for a wide range of clinical conditions. (tmrresearch.com)
Unconjugated as well as conjugated pneumococcal polysaccharide vaccines have been used with success for reducing the rate of pneumococcal infections, especially in adults and children. (tmrresearch.com)
ZOSTAVAX is a vaccine that is used for adults 50 years of age or older to prevent shingles (also known as zoster). (sheerhealth.ca)
But for the makers of newer pneumococcal vaccines that were first marketed for kids but which are now being aimed at older adults, it may turn out that the answer is actually yes. (huffingtonpost.ca)
There has been a large spillover effect in adults from the use of these vaccines in children, studies show. (huffingtonpost.ca)
So large, in fact, that adults appear to be getting the benefits of the vaccines without having been vaccinated - a bonus that may actually undermine the efforts of one manufacturer, Pfizer, to promote widespread use of its pneumococcal vaccine in older adults. (huffingtonpost.ca)
This same age group harbors pneumococcal isolates that are more likely to have antibiotic resistance when compared with older children and adults. (healio.com)
Adults over age 65 who received pneumococcal vaccine before age 65 also need a booster shot if it has been more than five years since being vaccinated. (thedacare.org)
Children older than 5 and adults with an increased risk for pneumococcal infections. (symptomfind.com)
While pneumococcal and influenza vaccinations are emphasized to a greater degree owing to the number of deaths caused annually by these preventable infections, there are other vaccinations that older adults should receive ( TABLE 1 ). (uspharmacist.com)
Streptococcus pneumoniae is the causative bacterium in more than 25% of the 1 million elderly adults who contract community-acquired pneumonia each year. (uspharmacist.com)
More than 500,000 cases of pneumococcal pneumonia occur each year in the United States, causing almost 50,000 deaths in adults and children. (asm.org)
We measured the capacity to opsonize Streptococcus pneumoniae serotype 6B and estimated the concentration of immunoglobulin G anti-6B capsular polysaccharide (PS) antibodies in 25 pre- and postimmune sera from adults immunized with a pneumococcal PS vaccine. (asm.org)
S. pneumoniae is a major causative agent for pneumonia, meningitis, and sepsis among young children and older adults ( 4 ). (asm.org)
Thus, there is a great need for pneumococcal vaccines effective among young children and older adults. (asm.org)
A May 2018 survey of U.S adults found that from 2008 to 2018, the proportion of respondents who consider vaccines "very important" to the health of society decreased nearly 13 percent. (njha.com)
Pneumococcal meningitis has a case-fatality rate of about 8% among children and 22% among adults, with neurologic sequelae often persisting among survivors. (vaccinesafety.edu)
Developed by the HELPinKIDS&Adults team at the University of Toronto, this guideline provides guidance for pain management during vaccine injections across the lifespan. (cfpc.ca)
Adults who receive the pneumococcal vaccine will sometimes report pain or redness at the site of the injection. (unitypoint.org)
Scientists recently revealed that they plan to study the pneumococcal vaccines in older adults to determine if there´s a strong immune response due to a higher dosage of the vaccine. (redorbit.com)
this includes children between six weeks and five years of age as well as adults who are 50 years of age can take the vaccine. (redorbit.com)

Prevnar 13 uses Company-pioneered conjugate technology that links pneumococcal polysaccharide sugar chains found on the surface of each bacterial serotype with a carrier protein. (fiercebiotech.com)
The candidate, the company found similar safety profile, as its Prevnar 13, a 13-valent pneumococcal conjugate vaccine. (tmrresearch.com)
People 65 and over who haven't received either vaccine should first receive Prevnar 13 followed 6 to 12 months later by Pneumovax 23. (jewishjournal.com)
Adverse events after the administration of Prevnar have been limited to areas of local swelling or erythema of 1 to 2 cm and some increase in the incidence of postimmunization fever when it is given with other childhood vaccines. (aappublications.org)
3 Hib, 3 Prevnar (pneumococcal vaccine) Hemophilus influ. (healthtap.com)
There are 3 shots for hib and for Prevnar ( pneumococcal vaccine ) in the first year (and 1 in the second year). (healthtap.com)
2-4 hib, 3-4 Prevnar (pneumococcal vaccine) Two different hib vaccines exist. (healthtap.com)
In the first study ( JCI-Insight ), newborn Rhesus monkeys were given a series of three shots with the existing Prevnar 13 pneumococcal vaccine. (medicalxpress.com)

Pneumococcal bacteria can cause many types of illnesses that range from mild to very severe. (infectioncontroltoday.com)
Vaccines are most often discussed with regard to young children, who should receive a series of inoculations against childhood illnesses like measles and polio. (weforum.org)
Also, as with all vaccines, the pneumococcal vaccine may not fully protect everyone who has it, so it's still important to know how to spot symptoms of these illnesses. (netdoctor.co.uk)
As you can see from the government's information above, these bacteria can be involved in a number of illnesses, including meningitis, pneumonia, and septicaemia (blood poisoning). (avn.org.au)
Pneumococcal vaccine is an immunization against Streptococcus pneumoniae , a bacterium that frequently causes meningitis and pneumonia in the elderly, and people with chronic illnesses. (medlineplus.gov)
Streptococcus pneumoniae (S. pneumoniae) is a widespread bacteria responsible for many illnesses, including meningitis, pneumonia , and sinus infections. (medicalnewstoday.com)
However, anyone who carries this bacteria can transmit it to others, potentially causing any of the illnesses above or pneumococcal meningitis. (medicalnewstoday.com)
Vaccines can help protect from serious illnesses, complications and save lives. (myhealth.gov.my)
This new immunization approach may someday stamp out pneumonia, meningitis and other illnesses. (physiciansweekly.com)
The situation led pharmaceutical companies to develop preventive vaccines, which have reduced deaths and illnesses, especially in developed nations. (physiciansweekly.com)
Pneumococcal vaccine watches bacteria, strikes only when needed: New immunization approach may someday stamp out pneumonia, meningitis and other illnesses. (physiciansweekly.com)
This vaccine works against bacterial pneumonia as well as other invasive pneumococcal illnesses, but researchers are not clear as to how effective the vaccine is in older adult populations. (redorbit.com)
Some older children with chronic illnesses may get the PPSV23 vaccine . (schmidtlaw.com)

PCV has been in use since 2000, when a 7-valent vaccine (PCV7) was licensed in the United States for routine use in children. (cdc.gov)
In 2010, PCV7 was replaced by a 13-valent vaccine. (cdc.gov)
The impact of PCV7 on pneumonia has been more difficult to evaluate," said Dr. Shah, "because of the specific cause of pneumonia is sometimes difficult to determine. (chop.edu)
The new 7-valent pneumococcal conjugate vaccine (PCV7) is composed of 7 purified capsular polysaccharides of S. pneumoniae, each coupled (conjugated) with a nontoxic variant of diphtheria toxin (CRM197). (healio.com)
Children who received one or more doses of PCV7 had 11.4% (95% Cl = 1.3% to 20.5%) fewer episodes of clinical pneumonia and 73.1% (95% CI = 3.0% to 88.3%) fewer episodes of pneumonia confirmed by x-ray with consolidation of 2.5 cm or greater. (healio.com)
In June 2008, the PCV7 (Prevenar®) vaccine was added to the New Zealand immunisation schedule. (bpac.org.nz)
It is expected the introduction of the PCV7 vaccine will result in similar benefits in New Zealand to those seen in the United States. (bpac.org.nz)
Children who meet the criteria are eligible for the PCV7 (pneumococcal conjugate, Prevenar®) vaccine and the 23PPV (pneumococcal polysaccharide, Pneumovax®23) vaccine at the ages recommended in the immunisation schedule. (bpac.org.nz)
In the past, children were given PCV7 vaccine , which only protected against 7 different pneumococcal bacteria types. (schmidtlaw.com)

Pneumococcal vaccines are vaccines against the bacteria Streptococcus pneumoniae. (wikipedia.org)

Conclusions Severe mental illness is a risk factor for lobar pneumonia, pneumococcal pneumonia, pneumococcal septicaemia and meningitis. (bmj.com)
These include pneumonia , meningitis and blood poisoning (septicaemia) . (netdoctor.co.uk)
It appears the Hib vaccine did nothing to reduce meningitis and septicaemia, and the other two vaccines didn't help either (all-ages graphs don't show better results for the vaccines). (avn.org.au)
A new breakthrough in the fight against pneumonia, meningitis and septicaemia has been announced today by scientists in Dublin and Leicester. (redorbit.com)
Rarely, invasion of the bloodstream can lead to more serious infections, including septicaemia and meningitis. (medworm.com)

In 2010, Brazil introduced a 10-valent pneumococcal conjugate vaccine (PCV10) to its National Immunization Program. (cdc.gov)
Vaccine safety will be monitored using standardized diary cards recording local and systemic side effects at week 1, 2, 4, 6, 8 after immunization. (clinicaltrials.gov)
See the CDC Hib vaccine information statement for additional details about this immunization. (symptomfind.com)
Study author Sir Brian Greenwood , Professor of Clinical Tropical Medicine at the London School of Hygiene & Tropical Medicine, who has worked for more than 30 years on pneumococcal vaccines in The Gambia, said: "This will be welcome news to the many developing countries that have invested in the introduction to PCV, and also to the Global Alliance for Vaccines and Immunization (GAVI) which has supported them financially. (lshtm.ac.uk)
CONCLUSIONS: We detected a small risk of incidental pneumonia associated with varicella vaccine in the 6th week after immunization. (medworm.com)
Rwanda announced that they would be one of the first two countries to introduce the pneumococcal vaccine into its national immunization program in the spring of 2009. (wikipedia.org)
PneumoADIP is funded by the Global Alliance for Vaccines and Immunization (GAVI). (wikipedia.org)
The 13 valent pneumococcal vaccine was introduced in the routine immunization schedule of the UK in April 2010. (wikipedia.org)
This report updates the last recommendations by the Advisory Committee on Immunization Practices (ACIP) concerning pneumococcal polysaccharide vaccine (MMWR 1989;38:64-8,73-6). (cdc.gov)

The pneumococcal polysaccharide vaccine (PPSV23 or Pneumovax®) protects against 23 types of pneumococcal bacteria. (cdc.gov)
Anyone who has ever had a life-threatening allergic reaction to a dose of PPSV23 or with a severe allergy to any component of the vaccine should not get the vaccine. (infectioncontroltoday.com)
Several studies have investigated the immunogenicity of PPSV23 in patients with IBD and have reported a marked inhibitory effect of immunosuppressive therapy on vaccine responses. (clinicaltrials.gov)
Researchers will evaluate participants' immune responses via blood samples drawn 28 days and 180 days post-injection, to compare responses between those who had previously been vaccinated with the PPSV23 vaccine and those who had not been. (rxpgnews.com)
The generic name for Pneumovax 23 is PPSV23, 23-valent pneumococcal polysaccharide vaccine. (jewishjournal.com)
PPSV23 is usually a single-dose vaccine, but a second dose is sometimes recommended. (symptomfind.com)

Before the first Hib vaccine was introduced in the U.S. in 1985, Haemophilus influenzae type B was the leading cause of acute bacterial meningitis in children younger than 5 years old. (symptomfind.com)

Pneumococcal polysaccharide vaccine (Pneumovax is one brand) gives at least 85% protection in those under 55 years of age for five years or longer. (wikipedia.org)
For over 30 years a pneumococcal vaccine called Pneumovax 23 has been recommended for everyone 65 and over. (jewishjournal.com)
Currently, Pneumovax 23, the inactivated pneumococcal polysaccharide vaccine (PPV), is indicated for all persons aged 65 and older. (uspharmacist.com)

the rash is a response to a toxin produced by the bacteria that cause strep throat. (encyclopedia.com)

Pneumococcal conjugate vaccine have been highly effective in reducing pneumonia and other invasive infections caused by Streptococcus pneumoniae bacteria. (news-medical.net)
The pneumococcal vaccine protects against infections caused by Streptococcus pneumoniae . (aarp.org)
Pneumococcal vaccines protect against meningitis, pneumonia and other infections caused by Streptococcus pneumoniae. (symptomfind.com)
Up to 1 million children, mostly in developing countries, die annually from infections caused by Streptococcus pneumoniae . (healio.com)

The bacterium Streptococcus pneumoniae can cause a type of pneumonia called pneumococcal pneumonia. (rxpgnews.com)

You can get either pneumococcal vaccine (but not both) when you get the influenza (flu) vaccine. (infectioncontroltoday.com)
This year's influenza immunisation programme has the earlier start date of 18th March, 2020, for people eligible for funded vaccines. (bpac.org.nz)
Who should get the influenza vaccine and is it free? (diabetesqld.org.au)
Queensland Health advises that the preferred influenza vaccine for people over 65 years of age is Fluad Quad. (diabetesqld.org.au)
The influenza vaccine takes approximately 10-14 days to help protect against influenza exposure. (diabetesqld.org.au)
Revaccination with a second influenza vaccine later in the same year is routinely NOT recommended. (diabetesqld.org.au)
Children aged 6 months to less than 9 years, who are receiving the influenza vaccine for the first time, also receive 2 doses, given at least four weeks apart. (diabetesqld.org.au)
Only one influenza vaccine is available for people eligible for the government-funded vaccine each year, except children who are receiving the influenza vaccine for the first time and require two doses. (diabetesqld.org.au)
8 In the United States, the CDC combines the death rates of pneumonia with influenza and estimates it to be the eighth leading cause of deaths in persons 65 years of age or older. (nvic.org)
3,4 Combined, pneumonia and influenza are the eighth leading cause of death in this country. (uspharmacist.com)
The live intranasal influenza vaccine [FluMist] is approved only for healthy persons aged 2 to 49 years. (uspharmacist.com)
As the main target for neutralizing antibodies, HA is currently used as the influenza vaccine potency marker and is measured by single radial immunodiffusion (SRID) 3 . (jove.com)
Moreover, despite evidence that NA also induces protective immunity 4 , the amount of NA in influenza vaccines is not yet standardized due to a lack of appropriate reagents or analytical method 5 . (jove.com)
Thus, simple alternative methods capable of quantifying HA and NA antigens are desirable for rapid release and better quality control of influenza vaccines. (jove.com)
These universal antibodies were then used to develop slot blot assays to quantify HA and NA in influenza A vaccines without the need for specific antisera 7,8 . (jove.com)
Other viruses that cause meningitis include varicella zoster (the virus that causes chicken pox and can appear decades later as shingles), influenza, mumps, HIV, and herpes simplex type 2 (genital herpes). (nih.gov)

The pneumococcal polysaccharide vaccine doesn't stimulate enough antibodies to be produced in this age group. (netdoctor.co.uk)
A first-in-human trial in 2016 demonstrated that the vaccine was well tolerated and that an increase in the desired antibodies was observed. (uk-cpi.com)
IL-17A increased pneumococcal killing by human neutrophils both in the absence and in the presence of antibodies and complement. (plos.org)
anthrax vaccine, adsorbed A cell-free, aluminum-hydroxide-adsorbed vaccine, administered to raise protective antibodies against Bacillus anthracis . (tabers.com)
The linkage improves the likelihood that the vaccine recipient will form antibodies against the primary target of the vaccine. (tabers.com)

To prevent such cases of meningitis, new vaccines will need to be developed to prevent or greatly reduce colonization with these capsular, non-vaccine-type bacteria. (news-medical.net)
Viruses are responsible for most cases of meningitis, but pneumococcal meningitis is caused by a bacteria called Streptococcus pneumoniae . (medicalnewstoday.com)

For meningitis or bloodstream infections, doctors will collect samples of cerebrospinal fluid or blood and send them to a laboratory for testing. (cdc.gov)
While this vaccine protects against pneumococcal meningitis and bloodstream infections, it is unclear how well it protects against bacterial pneumococcal pneumonia. (rxpgnews.com)
If that wasn't bad enough, S. pneumoniae can also cause bloodstream infections and meningitis, which are even more life-threatening than pneumonia. (jewishjournal.com)
That's good enough to protect against bloodstream infections and meningitis, so it still saves many lives, but the evidence that it prevents pneumonia isn't very strong. (jewishjournal.com)
The vaccine has been effective against bloodstream infections and pneumococcal meningitis, but not pneumococcal pneumonia. (redorbit.com)

There are more than 90 types of pneumococcal bacteria. (aarp.org)

Risks are associated with all vaccines, including PREVENAR Hypersensitivity to any vaccine component, including diphtheria toxoid, is a contraindication to its use. (science20.com)

The method involves testing a pneumococcal cell suspension with pooled and specific antisera directed against the capsular polysaccharide. (jove.com)

Although the etiology of the outbreak remains unclear, the identification of both S. pneumoniae and C. pneumoniae among trainees suggests that both pathogens may have contributed either independently or as cofactors to the observed increased incidence of pneumonia in the outbreak battalion and should be considered as possible etiologies in outbreaks of pneumonia in the military population. (biomedcentral.com)
The incidence of invasive pneumococcal infections peaks in children younger than 2 years, reaching rates of 228/100 000 in children 6 to 12 months old. (aappublications.org)

Therefore, prevention is the best available medical tool, and vaccines are the cornerstone of bacterial meningitis prevention. (symptomfind.com)
On November 1-2, 2009 PACE, a member of the World Pneumonia Day Coalition, sponsored a press conference, policymaker roundtable, rally, march and symposium to commemorate World Pneumonia Day in Bangladesh where the country's leaders and advocates focused their attention on the prevention and treatment of pneumonia. (wikipedia.org)
Growing focus of NGOs and global agencies on pneumonia prevention strategies has augmented the role of vaccines. (tmrresearch.com)
Given the severity of pneumococcal illness in people over 65, prevention in this age group has been critical. (jewishjournal.com)
While it might be hard to pronounce, prevention is easy - there's a vaccine. (unitypoint.org)

Due to the increasing rate of antibiotic resistance it is important to study newer ways to inhibit S. pneumoniae growth. (kenyon.edu)
Antibiotic resistance can be overcome by developing vaccines that target virulence factors on the surface of S. pneumoniae thereby disabling the bacteria . (kenyon.edu)
This aside, increasing trend of antibiotic resistance has spurred research in pneumococcal vaccines that can cover against wide range of pneumococci antigens. (tmrresearch.com)
Antibiotic treatment has become less effective since the prevalence of antibiotic-resistant S. pneumoniae has become very high ( 1 ). (asm.org)
We assessed antibiotic resistance rates in pneumococcal meningitis before and after pneumococcal conjugate vaccine (PCV) implementation. (eurosurveillance.org)

See CDC's meningococcal vaccine information statement for additional facts and recommendations. (symptomfind.com)
The meningococcal vaccines approved for use in the U.S. as of April 2014 provide protection specifically against what are known as groups A, C, W and Y meningococcus. (symptomfind.com)
It was a real joy to see the meningococcal A conjugate vaccine (MenAfriVac) introduced into the region within 10 years of its development. (mrc.ac.uk)
Epidemics caused by the serogroup in the vaccine are on the decline and the vaccine is currently provided at a cost cheaper than other available meningococcal vaccines. (mrc.ac.uk)
CBER conjugation technology has already been used by the Meningitis Vaccine Project-a partnership between PATH and the World Health Organization-for the development of a conjugate vaccine to prevent meningococcal meningitis in Africa. (fiercebiotech.com)
Meningococcal meningitis is caused by the bacterium Neisseria meningitides . (nih.gov)

New research from experts at the University of Nottingham could lead to an improved vaccine to protect against the bacterium, Neisseria meningitides that causes sepsis and meningitis. (news-medical.net)

People who live in close contact with many others may be more likely to contract pneumococcal meningitis. (medicalnewstoday.com)

S. pneumoniae is the leading cause of bacterial meningitis in children under the age of five. (nvic.org)

Such a vaccine would need to protect against colonization with most, if not all, pneumococci. (news-medical.net)
Using experimental mouse models, we show that repeated exposure to pneumococci leads to a subsequent reduction in duration of pneumococcal carriage, similar to what is observed in humans. (plos.org)
These organizations have been relentlessly working on the affordability of pneumococci vaccines in low- and middle-income countries. (tmrresearch.com)
Over half of all cases of bacterial meningitis in the United States are caused by pneumococci . (vaccinesafety.edu)
Pneumococci also cause meningitis with a high risk for sequelae and lethality [ 4 , 5 ]. (ersjournals.com)
The proportions of meningitis caused by ceftriaxone resistant pneumococci were 5.0% ± 0.8% in the pre-PCV period, but no ceftriaxone resistant isolates were identified since 2010. (eurosurveillance.org)

Anatomy 6

Organisms 19

Diseases 29

Chemicals and Drugs 39

Analytical, Diagnostic and Therapeutic Techniques and Equipment 9

Phenomena and Processes 7

Information Science 1

Health Care 2