Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.
Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
Two or more vaccines in a single dosage form.
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified.
Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.
Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent or treat AIDS. Some vaccines containing antigens are recombinantly produced.
Vaccines consisting of one or more antigens that stimulate a strong immune response. They are purified from microorganisms or produced by recombinant DNA techniques, or they can be chemically synthesized peptides.
Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
Vaccines made from antigens arising from any of the four strains of Plasmodium which cause malaria in humans, or from P. berghei which causes malaria in rodents.
Vaccines or candidate vaccines used to prevent PAPILLOMAVIRUS INFECTIONS. Human vaccines are intended to reduce the incidence of UTERINE CERVICAL NEOPLASMS, so they are sometimes considered a type of CANCER VACCINES. They are often composed of CAPSID PROTEINS, especially L1 protein, from various types of ALPHAPAPILLOMAVIRUS.
Vaccines or candidate vaccines used to prevent infection with NEISSERIA MENINGITIDIS.
Vaccines or candidate vaccines containing inactivated hepatitis B or some of its component antigens and designed to prevent hepatitis B. Some vaccines may be recombinantly produced.
A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)
A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.
An active immunizing agent and a viable avirulent attenuated strain of Mycobacterium tuberculosis, var. bovis, which confers immunity to mycobacterial infections. It is used also in immunotherapy of neoplasms due to its stimulation of antibodies and non-specific immunity.
A suspension of formalin-inactivated poliovirus grown in monkey kidney cell tissue culture and used to prevent POLIOMYELITIS.
Vaccines or candidate vaccines used to prevent and treat RABIES. The inactivated virus vaccine is used for preexposure immunization to persons at high risk of exposure, and in conjunction with rabies immunoglobulin, for postexposure prophylaxis.
Vaccines or candidate vaccines used to prevent infection with ROTAVIRUS.
Vaccines or candidate vaccines used to prevent infection with VIBRIO CHOLERAE. The original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist.
Vaccines used to prevent TYPHOID FEVER and/or PARATYPHOID FEVER which are caused by various species of SALMONELLA. Attenuated, subunit, and inactivated forms of the vaccines exist.
A live VACCINIA VIRUS vaccine of calf lymph or chick embryo origin, used for immunization against smallpox. It is now recommended only for laboratory workers exposed to smallpox virus. Certain countries continue to vaccinate those in the military service. Complications that result from smallpox vaccination include vaccinia, secondary bacterial infections, and encephalomyelitis. (Dorland, 28th ed)
Vaccines or candidate vaccines used to prevent or treat TUBERCULOSIS.
Immunoglobulins produced in response to VIRAL ANTIGENS.
A live, attenuated varicella virus vaccine used for immunization against chickenpox. It is recommended for children between the ages of 12 months and 13 years.
A vaccine consisting of DIPHTHERIA TOXOID; TETANUS TOXOID; and whole-cell PERTUSSIS VACCINE. The vaccine protects against diphtheria, tetanus, and whooping cough.
Vaccines used to prevent infection by MUMPS VIRUS. Best known is the live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.
Vaccines or candidate vaccines used to prevent infection with hepatitis A virus (HEPATOVIRUS).
Schedule giving optimum times usually for primary and/or secondary immunization.
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Any immunization following a primary immunization and involving exposure to the same or a closely related antigen.
A combined vaccine used to prevent MEASLES; MUMPS; and RUBELLA.
Vaccines or candidate vaccines used to prevent STREPTOCOCCAL INFECTIONS.
Vaccines or candidate vaccines used to prevent ANTHRAX.
Vaccines or candidate vaccines used to prevent infection with DENGUE VIRUS. These include live-attenuated, subunit, DNA, and inactivated vaccines.
Vaccines using VIROSOMES as the antigen delivery system that stimulates the desired immune response.
Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).
Any vaccine raised against any virus or viral derivative that causes hepatitis.
A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
Vaccine used to prevent YELLOW FEVER. It consists of a live attenuated 17D strain of the YELLOW FEVER VIRUS.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
A suspension of killed Yersinia pestis used for immunizing people in enzootic plague areas.
Suspensions of attenuated or killed fungi administered for the prevention or treatment of infectious fungal disease.
A live attenuated virus vaccine of duck embryo or human diploid cell tissue culture origin, used for routine immunization of children and for immunization of nonpregnant adolescent and adult females of childbearing age who are unimmunized and do not have serum antibodies to rubella. Children are usually immunized with measles-mumps-rubella combination vaccine. (Dorland, 28th ed)
Vaccines that are produced by using only the antigenic part of the disease causing organism. They often require a "booster" every few years to maintain their effectiveness.
Vaccines or candidate vaccines designed to prevent SAIDS; (SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME); and containing inactivated SIMIAN IMMUNODEFICIENCY VIRUS or type D retroviruses or some of their component antigens.
Vaccines or candidate vaccines used to prevent infection with SALMONELLA. This includes vaccines used to prevent TYPHOID FEVER or PARATYPHOID FEVER; (TYPHOID-PARATYPHOID VACCINES), and vaccines used to prevent nontyphoid salmonellosis.
Vaccines using supra-molecular structures composed of multiple copies of recombinantly expressed viral structural proteins. They are often antigentically indistinguishable from the virus from which they were derived.
Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent, usually a virus.
Combined vaccines consisting of DIPHTHERIA TOXOID; TETANUS TOXOID; and an acellular form of PERTUSSIS VACCINE. At least five different purified antigens of B. pertussis have been used in various combinations in these vaccines.
Vaccines or candidate vaccines used to prevent infection with CYTOMEGALOVIRUS.
Organized services to administer immunization procedures in the prevention of various diseases. The programs are made available over a wide range of sites: schools, hospitals, public health agencies, voluntary health agencies, etc. They are administered to an equally wide range of population groups or on various administrative levels: community, municipal, state, national, international.
Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.
A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.
Vaccines used to prevent POLIOMYELITIS. They include inactivated (POLIOVIRUS VACCINE, INACTIVATED) and oral vaccines (POLIOVIRUS VACCINE, ORAL).
Delivery of medications through the nasal mucosa.
Vaccines or candidate vaccines used to prevent or treat both enterotoxigenic and enteropathogenic Escherichia coli infections.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Vaccines or candidate vaccines used to prevent infection with WEST NILE VIRUS.
Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.
Vaccines or candidate vaccines used to prevent bacillary dysentery (DYSENTERY, BACILLARY) caused by species of SHIGELLA.
The measurement of infection-blocking titer of ANTISERA by testing a series of dilutions for a given virus-antiserum interaction end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (CPE) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (ID50) or die (LD50).
The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
An attenuated vaccine used to prevent and/or treat HERPES ZOSTER, a disease caused by HUMAN HERPESVIRUS 3.
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
Antibody-mediated immune response. Humoral immunity is brought about by ANTIBODY FORMATION, resulting from TH2 CELLS activating B-LYMPHOCYTES, followed by COMPLEMENT ACTIVATION.
A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.
Vaccines or candidate vaccines used to prevent infection by any virus from the family HERPESVIRIDAE.
The forcing into the skin of liquid medication, nutrient, or other fluid through a hollow needle, piercing the top skin layer.
Vaccines or candidate vaccines used to prevent infection with LEISHMANIA.
A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.
A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.
Aluminum metal sulfate compounds used medically as astringents and for many industrial purposes. They are used in veterinary medicine for the treatment of ulcerative stomatitis, leukorrhea, conjunctivitis, pharyngitis, metritis, and minor wounds.
Vaccines or candidate vaccines used to prevent infection with viruses from the genus SIMPLEXVIRUS. This includes vaccines for HSV-1 and HSV-2.
Substances elaborated by bacteria that have antigenic activity.
The formaldehyde-inactivated toxin of Corynebacterium diphtheriae. It is generally used in mixtures with TETANUS TOXOID and PERTUSSIS VACCINE; (DTP); or with tetanus toxoid alone (DT for pediatric use and Td, which contains 5- to 10-fold less diphtheria toxoid, for other use). Diphtheria toxoid is used for the prevention of diphtheria; DIPHTHERIA ANTITOXIN is for treatment.
Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.
Protection conferred on a host by inoculation with one strain or component of a microorganism that prevents infection when later challenged with a similar strain. Most commonly the microorganism is a virus.
Vaccines or candidate vaccines used to prevent infection with Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE).
Administration of a vaccine to large populations in order to elicit IMMUNITY.
Vaccines or candidate vaccines used to prevent conception.
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
Vaccines or candidate vaccines derived from edible plants. Transgenic plants (PLANTS, TRANSGENIC) are used as recombinant protein production systems and the edible plant tissue functions as an oral vaccine.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.
A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.
Active immunization where vaccine is administered for therapeutic or preventive purposes. This can include administration of immunopotentiating agents such as BCG vaccine and Corynebacterium parvum as well as biological response modifiers such as interferons, interleukins, and colony-stimulating factors in order to directly stimulate the immune system.
Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.
The relationship between an elicited ADAPTIVE IMMUNE RESPONSE and the dose of the vaccine administered.
Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
A highly contagious infectious disease caused by MORBILLIVIRUS, common among children but also seen in the nonimmune of any age, in which the virus enters the respiratory tract via droplet nuclei and multiplies in the epithelial cells, spreading throughout the MONONUCLEAR PHAGOCYTE SYSTEM.
Vaccines for the prevention of diseases caused by various species of Rickettsia.
An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Vaccines or candidate vaccines used to prevent infection with parainfluenza viruses in humans and animals.
Nonsusceptibility to the pathogenic effects of foreign microorganisms or antigenic substances as a result of antibody secretions of the mucous membranes. Mucosal epithelia in the gastrointestinal, respiratory, and reproductive tracts produce a form of IgA (IMMUNOGLOBULIN A, SECRETORY) that serves to protect these ports of entry into the body.
Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice.
A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.
A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 2. The H3N2 subtype was responsible for the Hong Kong flu pandemic of 1968.
Species of the genus INFLUENZAVIRUS B that cause HUMAN INFLUENZA and other diseases primarily in humans. Antigenic variation is less extensive than in type A viruses (INFLUENZA A VIRUS) and consequently there is no basis for distinct subtypes or variants. Epidemics are less likely than with INFLUENZA A VIRUS and there have been no pandemics. Previously only found in humans, Influenza B virus has been isolated from seals which may constitute the animal reservoir from which humans are exposed.
Vaccines or candidate vaccines used to prevent PSEUDORABIES (Aujeszky's disease), a herpesvirus of swine and other animals.
A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Membrane glycoproteins from influenza viruses which are involved in hemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of HA glycoproteins and nine of NA glycoproteins have been identified from INFLUENZA A VIRUS; no subtypes have been identified for Influenza B or Influenza C viruses.
Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
The process of keeping pharmaceutical products in an appropriate location.
Substances elaborated by viruses that have antigenic activity.
Acute VIRAL CNS INFECTION affecting mammals, including humans. It is caused by RABIES VIRUS and usually spread by contamination with virus-laden saliva of bites inflicted by rabid animals. Important animal vectors include the dog, cat, bat, fox, raccoon, skunk, and wolf.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.
Virus diseases caused by the ORTHOMYXOVIRIDAE.
A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell.
Proteins found in any species of protozoan.
The type species of the genus INFLUENZAVIRUS A that causes influenza and other diseases in humans and animals. Antigenic variation occurs frequently between strains, allowing classification into subtypes and variants. Transmission is usually by aerosol (human and most non-aquatic hosts) or waterborne (ducks). Infected birds shed the virus in their saliva, nasal secretions, and feces.
Infections with bacteria of the species NEISSERIA MENINGITIDIS.
Vaccines used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. Marker vaccines can be either a subunit or a gene-deleted vaccine.
A type of H. influenzae isolated most frequently from biotype I. Prior to vaccine availability, it was a leading cause of childhood meningitis.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.
Strains of Neisseria meningitidis which are the most common ones causing infections or disease in infants. Serogroup B strains are isolated most frequently in sporadic cases, and are less common in outbreaks and epidemics.
The non-susceptibility to infection of a large group of individuals in a population. A variety of factors can be responsible for herd immunity and this gives rise to the different definitions used in the literature. Most commonly, herd immunity refers to the case when, if most of the population is immune, infection of a single individual will not cause an epidemic. Also, in such immunized populations, susceptible individuals are not likely to become infected. Herd immunity can also refer to the case when unprotected individuals fail to contract a disease because the infecting organism has been banished from the population.
Specialized cells of the hematopoietic system that have branch-like extensions. They are found throughout the lymphatic system, and in non-lymphoid tissues such as SKIN and the epithelia of the intestinal, respiratory, and reproductive tracts. They trap and process ANTIGENS, and present them to T-CELLS, thereby stimulating CELL-MEDIATED IMMUNITY. They are different from the non-hematopoietic FOLLICULAR DENDRITIC CELLS, which have a similar morphology and immune system function, but with respect to humoral immunity (ANTIBODY PRODUCTION).
Vaccines or candidate vaccines used to prevent LYME DISEASE.
An acute infectious disease caused by RUBULAVIRUS, spread by direct contact, airborne droplet nuclei, fomites contaminated by infectious saliva, and perhaps urine, and usually seen in children under the age of 15, although adults may also be affected. (From Dorland, 28th ed)
Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
The expelling of virus particles from the body. Important routes include the respiratory tract, genital tract, and intestinal tract. Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).
Epidemics of infectious disease that have spread to many countries, often more than one continent, and usually affecting a large number of people.
Vaccines or candidate vaccines used to prevent or treat PSEUDOMONAS INFECTIONS.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
The giving of drugs, chemicals, or other substances by mouth.
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
Antibodies reactive with HIV ANTIGENS.
Antibodies to the HEPATITIS B ANTIGENS, including antibodies to the surface (Australia) and core of the Dane particle and those to the "e" antigens.
A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
The altered state of immunologic responsiveness resulting from initial contact with antigen, which enables the individual to produce antibodies more rapidly and in greater quantity in response to secondary antigenic stimulus.
A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.
Antigenic determinants recognized and bound by the B-cell receptor. Epitopes recognized by the B-cell receptor are located on the surface of the antigen.
A method of detection of the number of cells in a sample secreting a specific molecule. With this method, a population of cells are plated over top of the immunosorbent substrate that captures the secreted molecules.
A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM). It is most prevalent in the tropics and subtropics.
Viruses containing two or more pieces of nucleic acid (segmented genome) from different parents. Such viruses are produced in cells coinfected with different strains of a given virus.
Techniques where DNA is delivered directly into organelles at high speed using projectiles coated with nucleic acid, shot from a helium-powered gun (gene gun). One of these techniques involves immunization by DNA VACCINES, which delivers DNA-coated gold beads to the epidermis.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
Elements of limited time intervals, contributing to particular results or situations.
The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates.
A genus of REOVIRIDAE, causing acute gastroenteritis in BIRDS and MAMMALS, including humans. Transmission is horizontal and by environmental contamination. Seven species (Rotaviruses A thru G) are recognized.
Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.
Proteins isolated from the outer membrane of Gram-negative bacteria.
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Proteins found in any species of bacterium.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Infections with bacteria of the genus HAEMOPHILUS.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Resistance to a disease agent resulting from the production of specific antibodies by the host, either after exposure to the disease or after vaccination.
Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.
A highly contagious infectious disease caused by the varicella-zoster virus (HERPESVIRUS 3, HUMAN). It usually affects children, is spread by direct contact or respiratory route via droplet nuclei, and is characterized by the appearance on the skin and mucous membranes of successive crops of typical pruritic vesicular lesions that are easily broken and become scabbed. Chickenpox is relatively benign in children, but may be complicated by pneumonia and encephalitis in adults. (From Dorland, 27th ed)
An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.
Semidomesticated variety of European polecat much used for hunting RODENTS and/or RABBITS and as a laboratory animal. It is in the subfamily Mustelinae, family MUSTELIDAE.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Surveillance of drugs, devices, appliances, etc., for efficacy or adverse effects, after they have been released for general sale.
Established cell cultures that have the potential to propagate indefinitely.
Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER).
An infant during the first month after birth.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
A serotype of SALMONELLA ENTERICA which is the etiologic agent of TYPHOID FEVER.
Preparations of pathogenic organisms or their derivatives made nontoxic and intended for active immunologic prophylaxis. They include deactivated toxins. Anatoxin toxoids are distinct from anatoxins that are TROPANES found in CYANOBACTERIA.
Vaccines used to prevent infection by any virus from the family ADENOVIRIDAE.
A family of RNA viruses causing INFLUENZA and other diseases. There are five recognized genera: INFLUENZAVIRUS A; INFLUENZAVIRUS B; INFLUENZAVIRUS C; ISAVIRUS; and THOGOTOVIRUS.
A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.
Vaccines or candidate vaccines used to prevent or treat ALZHEIMER DISEASE.
Species of the genus LENTIVIRUS, subgenus primate immunodeficiency viruses (IMMUNODEFICIENCY VIRUSES, PRIMATE), that induces acquired immunodeficiency syndrome in monkeys and apes (SAIDS). The genetic organization of SIV is virtually identical to HIV.
A species of the genus FLAVIVIRUS which causes an acute febrile and sometimes hemorrhagic disease in man. Dengue is mosquito-borne and four serotypes are known.
A highly fatal, acute hemorrhagic fever, clinically very similar to MARBURG VIRUS DISEASE, caused by EBOLAVIRUS, first occurring in the Sudan and adjacent northwestern (what was then) Zaire.
An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
Proteins prepared by recombinant DNA technology.
The type species of MORBILLIVIRUS and the cause of the highly infectious human disease MEASLES, which affects mostly children.

Interrupting the transmission of respiratory tract infections: theory and practice. (1/1781)

Interruption of transmission has always been one of the most attractive approaches for infection control. The technologies available were severely limited before the development of appropriate vaccines. Mathematically, the proportion of those who need to be immune to interrupt transmission can be derived from the Ro, which represents the number of new cases infected by a single case when all contacts are susceptible. Purely respiratory infections have critical characteristics affecting transmission that are different from key childhood vaccine-preventable diseases spread by the respiratory route. They include frequent reinfections and antigenic changes of the agents. Pragmatic approaches to understanding their potential effect can be found in experimental and programmatic use of vaccines such as those for Haemophilus influenzae type b and influenza virus infections. Results of these experiences can in turn strengthen the development of transmission theory.  (+info)

Home delivery of heat-stable vaccines in Indonesia: outreach immunization with a prefilled, single-use injection device. (2/1781)

Extending immunization coverage to underserved populations will require innovative immunization strategies. This study evaluated one such strategy: the use of a prefilled, single-use injection device for outreach immunization by village midwives. The device, UniJect, is designed to prevent refilling or reuse. Stored at ambient temperatures for up to 1 month in midwives' homes, vaccine-filled UniJect devices were immediately available for outreach. Between July 1995 and April 1996, 110 midwives on the Indonesia islands of Lombok and Bali visited the homes of newborn infants to deliver hepatitis B vaccine to the infants and tetanus toxoid to their mothers. Observations and interviews showed that the midwives used the device properly and safely to administer approximately 10,000 sterile injections in home settings. There were no problems with excessive heat exposure during the storage or delivery of vaccine. Injection recipients and midwives expressed a strong preference for the UniJect device over a standard syringe. Use of the prefilled device outside the cold chain simplified the logistics and facilitated the speed and efficiency of home visits, while the single-dose format minimized vaccine wastage.  (+info)

A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida. (3/1781)

In this study, we have mapped and characterized a B cell epitope of sulfated glycoprotein ZP2 (ZP2) as a step toward the development of a multi-epitope zona pellucida (ZP) vaccine. Recombinant polypeptides expressed by random deoxyribonuclease-digested fragments of ZP2 cDNA were screened for binding to IE-3, a monoclonal antibody to murine ZP2. Positive clones contained cDNA inserts encoding polypeptide corresponding to ZP2(103-134). When normal or ovariectomized female mice were immunized with three overlapping peptides that span this region of ZP2 (101-120, 111-130, 121-140), only ZP2(121-140) elicited IgG antibodies that reacted with mouse ovarian ZP, indicative of the presence of native B epitope and helper T cell epitope in ZP2(121-140). To more finely map the ZP2 B cell epitope, a random peptide display library was screened with the IE-3 antibody, and a consensus tetramer sequence VxYK that matched the ZP2(123-126) sequence VRYK was located. Competitive immunofluorescence analysis with single alanine-substituted VxYK peptides ranked the relative contribution of the three critical B cell epitope residues as Y > V > K. A chimeric peptide was constructed that contained the YRYK motif of ZP2 and a bovine RNase T cell epitope. Although (C57BL/6xA/J) F1 (B6AF1) female mice immunized with the chimeric peptide developed ZP antibody response, this peptide elicited antibody only in mice of the histocompatibility complex (MHC) H-2(k or b) haplotype. In contrast, ZP2(121-140) peptide elicited antibody in inbred mice with three additional mouse MHC haplotypes. Moreover, although ZP2(121-140) contained a T cell epitope, no oophoritis was observed after immunization of B6AF1 mice with ZP2(121-140) in complete Freund's adjuvant (CFA). In a preliminary trial, female B6AF1 mice immunized with ZP2(121-140) in CFA had reduced litter sizes as compared with mice injected with CFA alone.  (+info)

Molecular characterization of a Haemaphysalis longicornis tick salivary gland-associated 29-kilodalton protein and its effect as a vaccine against tick infestation in rabbits. (4/1781)

The use of tick vaccines in mammalian hosts has been shown to be the most promising alternative tick control method to current use of acaricides, which suffers from a number of limitations. However, the success of this method is dependent on the identification, cloning, and in vitro expression of tick molecules involved in the mediation of key physiological roles with respect to the biological success of a tick as a vector and pest. We have sequenced and characterized a Haemaphysalis longicornis tick salivary gland-associated cDNA coding for a 29-kDa extracellular matrix-like protein. This protein is expressed in both unfed and fed immature and mature H. longicornis ticks. The predicted amino acid sequence of p29 shows high homology to sequences of some known extracellular matrix like-proteins with the structural conservation similar to all known collagen proteins. Immunization with the recombinant p29 conferred a significant protective immunity in rabbits, resulting in reduced engorgement weight for adult ticks and up to 40 and 56% mortality in larvae and nymphs that fed on the immunized rabbits. We speculate that this protein is associated with formation of tick cement, a chemical compound that enables the tick to remain attached to the host, and suggest a role for p29 as a candidate tick vaccine molecule for the control of ticks. We have discussed our findings with respect to the search of tick molecules for vaccine candidates.  (+info)

Impact of vaccines universally recommended for children--United States, 1990-1998. (5/1781)

At the beginning of the 20th century, infectious diseases were widely prevalent in the United States and exacted an enormous toll on the population. For example, in 1900, 21,064 smallpox cases were reported, and 894 patients died. In 1920, 469,924 measles cases were reported, and 7575 patients died; 147,991 diphtheria cases were reported, and 13,170 patients died. In 1922, 107,473 pertussis cases were reported, and 5099 patients died.  (+info)

Interleukin-12 as an adjuvant for an antischistosome vaccine consisting of adult worm antigens: protection of rats from cercarial challenge. (6/1781)

Our group previously demonstrated that a detergent extract (fraction S3) prepared from immature (4-week) Schistosoma mansoni parasites can induce partial, serum-transferable immunity to challenge infection in rats when administered as an alum precipitate. In the present study, we examined whether S3 prepared from adult (7-week) worms could similarly induce protection and whether immunity could be positively influenced by treatment with interleukin-12 (IL-12). IL-12 coadministered to Fischer rats and C57BL/6 mice at the time of S3 vaccination altered the prechallenge kinetics of S3-specific antibody titers in both species, ultimately leading to a stable enhancement of titers (relative to those in animals vaccinated without IL-12) in mice but not rats. Immunoblot analysis of prechallenge immune sera demonstrated that IL-12 treatment was associated with changes in the S3 antigen recognition profile in each species. Isotyping of specific antibodies in S3- plus IL-12-vaccinated mice prior to challenge infection revealed a moderate elevation in immunoglobulin G1 (IgG1) responses, strongly enhanced IgG2a and IgG2b responses, as well as diminished total serum IgE responses compared to those in mice given S3 only. In vaccinated rats, IL-12 profoundly suppressed specific IgG1 and enhanced IgG2b responses but did not affect IgG2a responses. S3- plus IL-12-vaccinated rats also produced less total IgE upon challenge infection. Enumeration of worm burdens revealed that vaccination with S3 plus IL-12 conferred 50% protection from cercarial challenge to rats, whereas rats given S3 only were not protected; mice were not protected by S3 vaccination regardless of IL-12 coadministration. The protection observed in S3- plus IL-12-vaccinated rats could not be transferred with serum, suggesting participation of an activated cellular component in the expression of immunity.  (+info)

Single-dose mucosal immunization with biodegradable microparticles containing a Schistosoma mansoni antigen. (7/1781)

The purpose of this work was to assess the immunogenicity of a single nasal or oral administration of recombinant 28-kDa glutathione S-transferase of Schistosoma mansoni (rSm28GST) entrapped by poly(lactide-co-glycolide) (PLG)- or polycaprolactone (PCL)-biodegradable microparticles. Whatever the polymer and the route of administration used, the equivalent of 100 microg of entrapped rSm28GST induced a long-lasting and stable antigen-specific serum antibody response, with a peak at 9 to 10 weeks following immunization. Isotype profiles were comparable, with immunoglobulin G1 being the predominant isotype produced. The abilities of specific antisera to neutralize the rSm28GST enzymatic activity have been used as criteria of immune response quality. Pooled 10-week sera from mice receiving PLG microparticles by the nasal or oral route neutralized the rSm28GST enzymatic activity, whereas sera of mice receiving either PCL microparticles, free rSm28GST, or empty microparticles inefficiently neutralized this enzymatic activity. Finally, this study shows that a single administration of these microparticles could provide distinct and timely release pulses of microencapsulated antigen, which might greatly facilitate future vaccine development.  (+info)

Heat shock protein-based therapeutic strategies against human immunodeficiency virus type 1 infection. (8/1781)

Heat shock proteins (hsps) and cyclophilins (CypA) are intracellular chaperone molecules that facilitate protein folding and assembly. These proteins are selectively expressed in cells following exposure to a range of stress stimuli, including viral infection. Hsp species are highly immunogenic, eliciting humoral, cytotoxic T lymphocyte (CTL), and natural killer (NK) cell responses against viruses, tumours, and infectious diseases. This review discusses the roles of stress proteins in immunity and viral life cycles, vis-a-vis the development of Hsp-based therapeutic strategies against human immunodeficiency virus type-1 (HIV-1) infection. Cumulative findings are cited implicating the requirement of CypA in HIV-1 replication and formation of infectious virions. Studies by our group show the upregulated expression of hsp27 and hsp70 during single-cycle HIV infections. These species redistribute to the cell surface following HIV-infection and heat stress, serving as targets for NK and antibody-dependent cellular cytotoxicity. Co-immunoprecipitation and Western blot studies show that hsp27, hsp70, and hsp78 complex with HIV-1 viral proteins intracellularly. Hsp70, hsp56, and CypA are assembled into HIV-1 virions. The ability of hsps to interact with HIV-1 viral proteins, combined with their inherent adjuvant and immunogenic properties, indicates that hsps may serve as vehicles for antigen delivery and the design of vaccines against acquired immunodeficiency syndrome.  (+info)

The VSD has conducted important vaccine-safety research since its inception in 1990, and since 2001 it has made changes that have enhanced its ability to answer urgent questions about vaccine safety and other immunization-related issues and to inform US vaccination policy.. The ability of the VSD to adapt to a changing environment is exemplified by the development of the DDM, the creation of DDFs, and the implementation of RCA projects. The DDM, a system for securely and quickly transferring data within the VSD, was developed in response to heightened confidentiality concerns. The DDM enabled the development of the DDFs. Together, the DDM and DDFs enabled the implementation of RCA, which is allowing researchers to monitor events in near real-time after the introduction of new vaccines and new vaccine recommendations. The VSD continues to refine previously used methodologies and develop new methodologies, such as the maximized sequential probability ratio test (maxSPRT), which is applicable to ...
In Canada, monitoring of vaccine adverse events is done via two systems. One, named Immunization Monitoring Program ACTive (IMPACT) is administered by the Canadian Paediatric Society with funding from the Immunization and Respiratory Infections Division of the Public Health Agency of Canada. According to the Societys website, IMPACT is a paediatric hospital-based national active surveillance network for adverse events following immunization, vaccine failures and selected infectious diseases in children that are, or are soon to be, vaccine preventable. Notice the conflicting agenda: monitoring disease to enable vaccine promotion and, at the same time, monitoring vaccine adverse events.. The second part of vaccine monitoring is performed by the Canadian Adverse Event Following Immunization Surveillance System (CAEFISS) which, up to May, 2005, was called The Vaccine Associated Adverse Events Surveillance System. The CAEFISS web page explains, This new name is in harmony with international ...
Language: English (with materials in Arabic, Chinese, French, Russian and Spanish).Audience: Ministries of Health, national regulatory authorities, health-care personnel and members of the public.The website of the Global Advisory Committee on Vaccine Safety provides the conclusions of the biannual meetings of the Committee. These relate to general safety issues relevant to
On the basis of computerized International Classification of Diseases, Ninth Revision codes, 5 apparent cases of GBS generated a signal after vaccination with MCV4. Each of the GBS cases had been reviewed after its appearance, and none represented a true instance of new onset of GBS symptoms during the observation window of days 1 through 42. Two were instances of follow-up for preexisting GBS; 1 had not been diagnosed with GBS but rather with a different neurologic syndrome that did not meet our case definition; 1 was an instance of rule-out of a differential diagnosis of GBS; and 1 had symptom onset on day 0 and, thus, was not considered plausibly related to vaccination.. In summary, the reasons for the 10 signals fell into 1 of 7 categories: (1) a confirmed vaccine-safety problem (MMRV-seizure); (2) temporal changes in incidence or coding (possibly the second RotaTeq gastrointestinal bleeding signal); (3) other confounding (by age: the first RotaTeq-gastrointestinal bleeding signal); (4) ...
The Food and Drug Administration (FDA) licensed the first 2009 influenza A (H1N1) monovalent vaccines (H1N1 vaccines) on September 15, 2009 (1). The H1N1 vaccines are available as a live, attenuated monovalent vaccine (LAMV) for intranasal administration and as monovalent, inactivated, split-virus or subunit vaccines for injection (MIV). The licensure and manufacturing processes for the monovalent H1N1 vaccines were the same as those used for seasonal trivalent inactivated (TIV) or trivalent live, attenuated influenza vaccine (LAIV); none of these vaccines contains an adjuvant (1). Vaccine safety monitoring is an important component of all vaccination programs. To assess the safety profile of H1N1 vaccines in the United States, CDC reviewed vaccine safety results for the H1N1 vaccines from 3,783 reports received through the U.S. Vaccine Adverse Event Reporting System (VAERS) and electronic data from 438,376 persons vaccinated in managed-care organizations in the Vaccine Safety Datalink (VSD), ...
By joining Vaccine Choice Canada, you receive our internationally acclaimed newsletter twice a year as well as privileged access to our newsletter archive. To support our educational and outreach work , please join Vaccine Choice Canada today. Sign Me Up!. ...
3. These decisions highlight the inadequacy and possible suppression of vaccine safety science.. a. There is overwhelming, uncontested scientific evidence that mercury causes neurological damage and immune dysfunction.. b. The health of these children improved dramatically when they were treated for heavy metal toxicity and immune dysfunction. Their condition was treatable, not immutable.. c. The government removed thimerosal from routine childhood vaccines because of safety concerns.. d. The government has failed to do serious research on children with regressive autism.. e. Until December 2009, the Centers for Disease Control denied any real rise in autism prevalence.. f. Petitioners were unable to gain access in this Court to taxpayer-financed data from the Vaccine Safety Datalink, the most important source of data on vaccine safety.. g. HHS assertion of no thimerosal-autism link is dubious.. 4. These test cases further erode trust in the National Immunization Program, when trust is already ... For 30 years, the US Department of Health and Human Services (HHS) broke the law regarding vaccine safety, and no one noticed or cared.. Then two men came along and discovered the scandal: Robert F Kennedy, Jr. (twitter), head of the World Mercury Project, and Del Bigtree (twitter 1, twitter 2, FB, web), the producer of the film Vaxxed. They filed papers in court, and they won their case.. Here is the issue in a nutshell: In 1986, a law, the National Childhood Vaccine Injury Act, was passed. It insanely excused vaccine makers from legal liability stemming from unsafe vaccines and the injuries they cause. Buried in the law was a provision ordering the US Department of Health and Human Services (HHS) to update Congress, every two years, on its efforts to improve vaccine safety.. Kennedy and Bigtree thought it would be very interesting to read these HHS reports-all 16 of them. So ...
Its a great Indian success story, said Dr. Jacob John, a former virologist of the Christian Medical College (CMC), Vellore. He was referring to MenAfriVac, a meningitis A vaccine manufactured by the Pune-based Serum Institute of India. The vaccine passed the litmus test during a large-scale vaccine campaign in Banikoara district in the Republic of Benin, West Africa.. In the first-ever use in a developing country, the vaccine remained stable outside the cold chain at temperatures not exceeding 40 degree C for not more than four days. The vaccine should normally be kept in a cold chain at 2-8 degree C. The results of the vaccination programme funded by GAVI and WHO/PATH (which also provided training, supervision, evaluation) were published recently in the Vaccine journal.. An independent body under the guidance of the Ministry of Health in Benin conducted active monitoring for adverse events following immunization (AEFI) by comparing the rate and severity of AEFIs in the study area and a ...
A vaccine-preventable disease is an infectious disease for which an effective preventive vaccine exists. If a person acquires a vaccine-preventable disease and dies from it, the death is considered a vaccine-preventable death. The most common and serious vaccine-preventable diseases tracked by the World Health Organization (WHO) are: diphtheria, Haemophilus influenzae serotype b infection, hepatitis B, measles, meningitis, mumps, pertussis, poliomyelitis, rubella, tetanus, tuberculosis, and yellow fever. The WHO reports licensed vaccines being available to prevent, or contribute to the prevention and control of, 25 vaccine-preventable infections. In 2012, the World Health Organization estimated that vaccination prevents 2.5 million deaths each year. If there is 100% immunization, and 100% efficacy of the vaccines, one out of seven deaths among young children could be prevented, mostly in developing countries, making this an important global health issue. Four diseases were responsible for 98% of ...
When a promising nicotine vaccine failed in clinical trials a few years ago, scientists from The Scripps Research Institute were determined to keep trying to help smokers overcome their addiction. Now the team has designed a more effective nicotine vaccine and proven that the structures of molecules used in vaccines is critical.
Childhood vaccines protect children from a variety of serious or potentially fatal diseases, including diphtheria, measles, polio and whooping cough (pertussis). If these diseases seem uncommon - or even unheard of - its usually because these vaccines are doing their job.. Still, you might wonder about the benefits and risks of childhood vaccines. Here are straight answers to common questions about childhood vaccines.. A natural infection might provide better immunity than vaccination - but there are serious risks. For example, a natural chickenpox (varicella) infection could lead to pneumonia. A natural polio infection could cause permanent paralysis. A natural mumps infection could lead to deafness. A natural Haemophilus influenzae type b (Hib) infection could result in permanent brain damage. Vaccination can help prevent these diseases and their potentially serious complications.. Vaccines do not cause autism. Despite much controversy on the topic, researchers havent found a connection ...
Given the absence of a framework to set a national vaccine-safety research agenda, the National Vaccine Plan should call for expanded funding for safety research and include establishing a permanent group to advise the government on safety issues, the report says. Little vaccine research supported by the National Institutes of Health appears to be geared toward safety, the committee noted. Moreover, as the number and kinds of vaccines have increased, funding to monitor safety has not. The monitoring system has successfully caught problems such as a rare but severe intestinal injury linked to a discontinued rotavirus vaccine, but the Immunization Safety Office within the Centers for Disease Control and Prevention needs more resources to do its work. A new vaccine safety advisory group could guide efforts to address potential safety concerns and the development of a research agenda with clear priorities ...
And we are told by the CDC that all the science has shown no connection between vaccines and ASD. But what did they actually look at? Did they do actual physiological studies on and as to the effect of vaccines and multiple vaccines on actual human being, and/or lab animals? No, they did not. What did they do and have they done? They did only population studies on one single vaccine, (the MMR vaccine); and population studies on one single vaccine ingredient, (Thimerosal, aka ethyl mercury). No studies were done on any other vaccines, nor other vaccine ingredients, nor were any done on combined multiple and nor repeated vaccine doses. And they tell us that they have done and looked at all the vaccine safety science; and apparently all the science that they feel would and should ever being needed. The general population and even the medical profession has believed this to be sufficient. There has as well never been done any officially recognized small nor large scale epidemiological study done, ...
The Advisory Committee on Immunization Practices (ACIP) COVID-19 Vaccine Safety Technical (VaST) Work Group has reviewed post-authorization COVID-19 vaccine safety data on a weekly basis since the start of the U.S. vaccination program, the CDC said in a statement.. The VaST session on May 17, 2021, included several presentations on myocarditis following mRNA vaccines, from the Department of Defense (DoD), the Vaccine Adverse Event Reporting System (VAERS), and Vaccine Safety Datalink (VSD), the statement continued. There were also brief updates from the Veterans Administration (VA) and the Clinical Immunization Safety Assessment (CISA) groups about their plans for future investigation of myocarditis.. The report noted that reports of vaccine-induced myocarditis have occurred predominantly in adolescents and young adults, more often in males than females, more often following dose 2 than dose 1, and typically within 4 days after vaccination.. VaSt went on to recommend that Further ...
This article in Pace International Law Review reports on how the pharmaceutical companies have been given immunity from being sued for vaccine damage, in the USA. This lack of accountability is of great concern.. Supreme Court Gives Big Pharmaceuticals a Vaccination Against Lawsuits. Vaccines are a type of unavoidably unsafe product; that is, a vaccine is a product that is incapable of being made safe for its intended and ordinary use … The Court takes as true the premise that vaccines are unavoidably unsafe. Since the government mandates the use of an unavoidably unsafe product, it is reasonable to believe that some people will be injured by it. Vaccine makers will take a big hit if everyone that is injured sues, and an even bigger hit if plaintiffs are successful - since vaccine makers will then be obligated to compensate their victims.. ...
CDC Clinical Immunization Safety Assessment (CISA) Project. National network of vaccine safety experts from the CDCs Immunization Safety Office (ISO), seven medical research centers, and other partners, which provides a comprehensive vaccine safety public health service to the nation.. Ensuring the Safety of Vaccines in the United States. Information from the CDC. If You Choose Not to Vaccinate Your Child, Understand the Risks and Responsibilities. If you choose to delay some vaccines or reject some vaccines entirely, there can be risks. Follow these steps from the CDC to protect your child, your family, and others.. Influenza Vaccine Safety. Childhood Influenza Immunization Coaltion (CIIC) FAQs. The Childhood Immunization Schedule and Safety: Stakeholder Concerns, Scientific Evidence, and Future Studies. Institute of Medicine (IOM). The Journey of Your Childs Vaccine. The vaccines your child gets have a long journey before they arrive at your pediatricians office. All along the way, ...
Posted: March 18, 2011 05:46 PM. The Centers for Disease Control and Prevention wants to study autism as a possible clinical outcome of immunization, as part of its newly adopted 5-year research agenda for vaccine safety, the agency said on its website.. The CDC will also study mitochondrial dysfunction and the potential risk for post-vaccine neurological deterioration, and convene an expert panel on the feasibility of studying health outcomes such as autism among vaccinated and unvaccinated children.. The CDC plan adopts recommendations approved by the National Vaccine Advisory Committee of the US Department of Health and Human Services. It also comes one month after the federal governments leading autism body, the Interagency Autism Coordinating Committee (IACC), announced a shift in research priorities toward environmental triggers for autism, which the IACC said could include toxins, biological agents and adverse events following immunization.. The Centers for Disease Control and ...
The National Vaccine Information Center (NVIC), a non-profit vaccine safety group, recently conducted an independent review of the contents of childhood vaccines and found that many of them are tainted with ingredients that would shock most parents. According to the manufacturer-produced package inserts included with each vaccine batch, many vaccines are made with disturbing ingredients like aborted human fetal proteins, altered DNA material, and even genetically-modified (GM) human albumin.. This shocking information was compiled as part of an NVIC safety review on the childhood vaccination schedule, which has been called into question in recent years due to a steady increase in cases of autism and other forms of neurological and brain damage among vaccinated children. As it turns out, there are at least eight, and as many as 23, vaccines routinely administered to children that contain one or more of these questionable ingredients - and if the general public truly knew about this, there would ...
To pilot test a mobile phone SMS system that will provide periodical messaging texts to mothers or custodians of infants who come for their first dose vaccines within the first 3 months of life to improve timely immunization coverage, vaccine acceptance and ensure vaccine safety monitoring. The intervention will include a cloud-based information system alimented by mobile phone data entry at the health post nurse level, that links child vaccination status and is able to remind parents and nurses of the need for next vaccination appointment and provide a system for reporting of adverse events following immunization in the immediate post-vaccination period ...
Only a year ago, mRNA vaccines were only known to a few people in the scientific community. Today, millions of people are pinning their hopes on this genetic-based immunization. However, the production process of mRNA vaccines is particularly complicated and requires professional technical capabilities. Not only that, the biggest bottleneck restricting global vaccine supply at present is the lack of raw materials. As the global demand for the COVID-19 vaccine far exceeds supply, the lack of raw materials needed to produce mRNA vaccines may lead to a more general shortage of vaccines.. Obviously, many COVID-19 vaccine raw materials, packaging materials, consumables, and equipment are in short supply, which may cause some COVID-19 vaccine manufacturers to fail to fulfill their current vaccine production commitments. BOC Sciences has been doing its best to help provide basic nucleotide raw materials to support the research and production of mRNA vaccines.. BOC Sciences has a complete production and ...
Only a year ago, mRNA vaccines were only known to a few people in the scientific community. Today, millions of people are pinning their hopes on this genetic-based immunization. However, the production process of mRNA vaccines is particularly complicated and requires professional technical capabilities. Not only that, the biggest bottleneck restricting global vaccine supply at present is the lack of raw materials. As the global demand for the COVID-19 vaccine far exceeds supply, the lack of raw materials needed to produce mRNA vaccines may lead to a more general shortage of vaccines.. Obviously, many COVID-19 vaccine raw materials, packaging materials, consumables, and equipment are in short supply, which may cause some COVID-19 vaccine manufacturers to fail to fulfill their current vaccine production commitments. BOC Sciences has been doing its best to help provide basic nucleotide raw materials to support the research and production of mRNA vaccines.. BOC Sciences has a complete production and ...
Posted: March 18, 2011 05:46 PM. The Centers for Disease Control and Prevention wants to study autism as a possible clinical outcome of immunization, as part of its newly adopted 5-year research agenda for vaccine safety, the agency said on its website.. The CDC will also study mitochondrial dysfunction and the potential risk for post-vaccine neurological deterioration, and convene an expert panel on the feasibility of studying health outcomes such as autism among vaccinated and unvaccinated children.. The CDC plan adopts recommendations approved by the National Vaccine Advisory Committee of the US Department of Health and Human Services. It also comes one month after the federal governments leading autism body, the Interagency Autism Coordinating Committee (IACC), announced a shift in research priorities toward environmental triggers for autism, which the IACC said could include toxins, biological agents and adverse events following immunization.. The Centers for Disease Control and ...
THERE IS A DISTURBING AND CONSISTENT trend in the vaccine safety literature for government-affiliated researchers in the misinterpretation of negative results from studies of specific, serious adverse events from vaccines, such as autism, encephalopathy, ADHD, and other serious neurological injuries. Heres the (il)logic flow: Conduct a retrospective epidemiological study (case/control, or cohort) with a relatively…
Our data demonstrate that a single dose of a DNA vaccine or a purified inactivated virus vaccine provides complete protection against the ZIKV challenge in mice, said senior author Dan H. Barouch, adding Importantly, we showed that vaccine-induced antibodies provided protection, similar to existing vaccines for other flaviviruses.. The researchers tested two vaccine candidates: a DNA vaccine developed in the Barouch laboratory at BIDMC, and a purified inactivated virus vaccine developed at WRAIR. The DNA vaccine used gene sequences from a ZIKV strain from Brazil to elicit immune responses.. Four weeks following vaccination, mice were exposed to the Brazilian strain of ZIKV, which had previously been shown to cause defects in fetal mice similar to those observed in ZIKV infected humans. All vaccinated mice were protected from ZIKV replication. Other mice were vaccinated and exposed to infection eight weeks later and were also protected from infection.. Barouch noted that the effectiveness of ...
Most parents have their children vaccinated. However, some parents have concerns about the safety of vaccines.. For instance, some worry that the MMR vaccine might cause autism. But vaccine safety experts agree that the rise in autism rates is not due to the vaccine. In addition, the Institute of Medicine looked into these claims and found no link between autism and the MMR vaccine. Whats more, the Lancet recently retracted the 1998 study that first suggested a link between the two.. Most health experts agree that the benefits of vaccination outweigh the risks. Nonetheless, if you are worried about childhood vaccines, talk with your childs doctor. Here are some questions you might ask:. ...
Most parents have their children vaccinated. However, some parents have concerns about the safety of vaccines.. For instance, some worry that the MMR vaccine might cause autism. But vaccine safety experts agree that the rise in autism rates is not due to the vaccine. In addition, the Institute of Medicine looked into these claims and found no link between autism and the MMR vaccine. Whats more, the Lancet recently retracted the 1998 study that first suggested a link between the two.. Most health experts agree that the benefits of vaccination outweigh the risks. Nonetheless, if you are worried about childhood vaccines, talk with your childs doctor. Here are some questions you might ask:. ...
Global Vaccines Market to reach US$ 60 Billion by the year 2022. Pediatric vaccines market is having a dominant market share compared to Adult vaccines market. By 2022 Pediatric vaccines market share will be double the size of adult vaccines market share. Worldwide the number of infants immunized by influenza vaccines remain considerably low than that of adults immunized in year 2017. While the number of Rotavirus doses administered in infants is forecast to increase over the years and reach nearly 15 Million by the year 2022. Adult Vaccine Market Share Analysis. Out of the total 9 Adult vaccines (Influenza, Cervical Cancer, Zoster, MMRV, Pneumococcal, Meningococcal, Hepatitis, TdaP, Travel) studied in the report Influenza vaccines dominates the adult vaccine market in 2017.. Pediatric Vaccine Market Share Analysis. Our analysis found that in year 2017; Pneumococcal and Combination vaccine together accounts for nearly 50% of the pediatric vaccine market share. Other Pediatric vaccines market ...
National, State, and Selected Local Area Vaccination Coverage Among Children Aged 19-35 Months - United States, 2013 -- Assessment of Rabies Exposure Risk in a Group of U.S. Air Force Basic Trainees - Texas, January 2014 -- Update on Cases of Delayed Hemolysis After Parenteral Artesunate Therapy for Malaria - United States, 2008 and 2013 -- Assessing and Mitigating the Risks for Polio Outbreaks in Polio-Free Countries - Africa, 2013-2014 -- QuickStats: Weight Perception Among Children and Adolescents Aged 8-15 Years, by Sex and Body Mass Index (BMI) Category - National Health and Nutrition Examination Survey (NHANES), United States, 2005-2012 -- Notifiable Diseases and Mortality Tables ...
In 2004, NIAID directed Novartis Vaccines and Diagnostics (formerly Chiron Corporation) to produce 40,000 doses of an experimental H9N2 vaccine at its vaccine manufacturing facility in Siena, Italy. Some of the vaccines were formulated with Novartiss MF59 adjuvant.. Dr. Atmar and his colleagues tested the vaccines in volunteers aged 18 to 34 in this Phase I clinical trial. Phase I vaccine trials assess candidate vaccines safety and ability to stimulate an immune system response, and are not designed to determine whether the vaccine would prevent infection by naturally occurring virus. The researchers vaccinated 48 volunteers with non-adjuvanted H9N2 vaccine (made from inactivated virus) at one of four dosages - 3.75, 7.5, 15 or 30 micrograms. An additional 48 volunteers received MF59-adjuvanted vaccine at one of the same four dosages. Volunteers were vaccinated twice, with inoculations spaced 28 days apart. An avian flu vaccine, like the seasonal flu vaccine, should stimulate antibodies, which ...
In this report, the committee who was asked to review aspects of this program, recommends that two new oversight groups are needed to ensure that the policies and procedures of the Vaccine Safety Datalink (VSD) and its data sharing program -- which is intended to give researchers access to patient data that will help them study vaccine safety issues -- are implemented as fairly and openly as possible.
Vaccines are an important part of your dogs health but knowing which vaccines your dog needs can be a little confusing. The best source of advice for what vaccines your dog needs is your veterinarian who knows your dogs unique health history. Things like dog breed, age, and the region in which you live will influence what vaccines your dog needs to stay healthy and prevent illness and disease. Vaccines should not be over-administered, though, because it increases the risk of adverse reactions in your dog. For this reason, it is important to educate yourself about what vaccines may be necessary for your dog so that you can make an informed decision about what vaccines your dog really needs. There are vaccines that are considered core vaccines - vaccines that are necessary for all dogs, and non-core vaccines - vaccines that should only be administered if your dog has increased risk of various disease/illness from a variety of factors. Below are general vaccine recommendations for dogs based ...
In an open letter to the head of the World Health Organization, Dr. Sing Hang Lee, MD, the director of the Milford Molecular Diagnostics Laboratory in Milford, Connecticut, claims members of the WHOs Global Advisory Committee on Vaccine Safety (GACVS) deliberately manipulated scientific data relating to the safety of HPV vaccines Gardasil® and Cervarix®.. The letter states that the emails, obtained via a Freedom of Information request, clearly demonstrate members of the GAVCS, the CDC and the Japanese Ministry of Health, Labor and Welfare knew before the February 26, 2014 Tokyo public hearing that one of their own experts showed scientific evidence that HPV vaccination does increase cytokines, including tumor necrosis factor (TNF), particularly at the injection site compared to other vaccines. This increase can be attributed to HPV L1 gene DNA fragments, the viral DNA fragments, in the HPV vaccines that bind to aluminum adjuvants. This mechanism explains why serious adverse reactions occur ...
UK Government In Secret Payments For Childhood Vaccine Damage. London Evening Standard , March 16 2005. Secret payments to patients disabled by childhood vaccines are revealed today. New figures show the Government has paid out £3.5 million to families who claim their children fell sick after jabs. Over the years, up to 30,000 people have battled for compensation, with only a handful winning their cases.. The payouts - all made since 1997 - were revealed under the Freedom of Information Act. But ministers refuse to say which injections were involved - claiming such records are not kept. The money was paid under a little-known government scheme for patients who have suffered adverse effects from immunisations. Details of successful claims are never publicised - with ministers anxious not to encourage applications. Families must convince health chiefs that the injections their children were given as part of public health programmes were directly responsible for making them seriously ill. Payouts ...
The National Adverse Event Following Immunisation (AEFI) Committee has completed an in-depth case review of 498 serious and severe events, of which 26 cases have been reported to be potential thromboembolic (formation of a clot in a blood vessel that might also break loose and carried by the blood stream to plug another vessel) events following administration of Covishield vaccine with a reporting rate of 0.61 cases/ million doses.. There were no potential thromboembolic events reported following administration of Covaxin vaccine, the ministry said.. As alerts were raised in some countries on post-vaccination embolic and thrombotic events on March 11, particularly with AstraZeneca-Oxford vaccine (which is sold in India by the Serum Institute as Covishield), a decision was taken to conduct an urgent in-depth analysis of the adverse events (AE) in India in the light of global concerns, the ministry said.. The death of Snehal Lunawat, a lecturer in Nasik who was administerd Covishield in ...
This may challenge the conventional wisdom, said senior author Dr. Ali Rowhani-Rahbar, assistant professor of epidemiology. Usually, we look to see if a drop in immunization results in an outbreak. But we were interested in looking at the relationship the other way around: Does an outbreak lead to increased immunization? We found that it did not in Washington state.. Dr. Rowhani-Rahbar said many factors affect parental decisions on whether to delay or refuse vaccines, including fears of adverse effects. But the added risk of adverse events following immunization is very small - roughly one in a few thousand for some of the most common events (e.g., febrile seizures following immunization with measles-containing vaccines), he said. Washington has one of the highest U.S. non-medical exemption rates in the country from required kindergarten vaccinations.. While overall immunization rates remained the same for the state, researchers found significant changes on the county level. Vaccination rates ...
Title:Vaccine Adjuvants: Key Tools for Innovative Vaccine Design. VOLUME: 13 ISSUE: 20. Author(s):Peggy Riese, Kai Schulze, Thomas Ebensen, Blair Prochnow and Carlos A. Guzmán. Affiliation:Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7 38124 Braunschweig, Germany.. Keywords:Adjuvants, adjuvant combinations, adjuvant licensing, delivery systems, limitations, regulatory aspects, vaccines, parenteral vaccination, mucosal vaccination.. Abstract:Vaccines represent the most efficient tool for preventing diseases caused by infectious pathogens. During the last century significant progress has been made in vaccine development, resulting in the eradication or control of several diseases. However, the emergence of new pathogens and the inadequate protection conferred by some existing vaccines render necessary new vaccination strategies. Newly arising immunization approaches, such as subunit vaccines and mucosal administration, make the use ...
Developing the vaccines was a worldwide collaboration. Billions of dollars were invested in multiple companies and vaccine platforms at once to increase the likelihood of having at least one vaccine, if not multiple vaccines, developed, evaluated and produced.. Both the Pfizer and Moderna COVID-19 vaccines have undergone extensive study and review with tens of thousands of immunizations already accomplished and all data suggest that the vaccines are not only safe but highly effective. This process involves gathering data about the effectiveness and potential effects of the vaccines that are reviewed by multiple federal agencies responsible for public health and safety. The vaccines have also been tested among a broad range of ages, races, ethnicities, and people with pre-existing medical conditions. These safety approval boards include scientists and experts in infectious disease and vaccination that have no connection with the companies producing the vaccines. These individuals evaluate the ...
Vaccine research is a major focus of AutismDads time. Parents of vaccine-damaged children research testing, vaccine safety & vaccine info regularly.
The immune system recognizes vaccine agents as foreign, destroys them, and remembers them. When the virulent version of an agent comes along, the immune system is thus prepared to respond. This long term immunity relies heavily upon the generation of so called B cells, which will generate antibodies that will bind to pathogens and mark them for destruction. Specifically, almost all vaccine formulations induce two types of B-cells: memory B cells and antibody producing B-cells called plasma cells. Adjuvants, agents which modify the effect of other agents while having few, if any direct effects when given by themselves, are many times used to modify (in this case augment) the effects that a vaccine has on disease resistance. However, the reasons why certain vaccine adjuvants are more or less effective at inducing immune responses often remains unclear.. This article provides a very exciting new insight because it seems to change the traditional textbook paradigm on relationship between plasma ...
contributed by Mr. Jordan Mifsud teacher of Biology. Why get vaccinated against covid-19?. Getting a COVID-19 vaccine can help protect from the virus by creating an antibody response in your body without having to become sick with COVID-19. If you still get COVID-19 infection, the vaccine might keep you from becoming seriously ill. Getting vaccinated also helps protect people around you from COVID-19.. Are vaccines 100% effective against Covid-19?. No, but vaccines are more effective than all other preventative measures against infectious diseases. The Maltese authorities have authorised three vaccines against Covid-19; the Pfizer-BioNTech COVID-19 vaccine, the Moderna COVID-19 vaccine and lately the AstraZeneca COVID-19 vaccine. Similarly to other vaccines, these vaccines have an efficacy rate between 95% and about 70%. For example, 95% of people who get the Pfizer vaccine are protected from becoming seriously ill with the virus.. Who should get vaccinated?. These vaccines are for people aged ... 1 , Global Vaccine Market Features and Trends Miloud Kaddar Senior Adviser, Health Economist WHO, IVB, Geneva 2 , GLOBAL VACCINE MARKET  MAIN FEATURES OF THE VACCINE MARKET ?  NEW TRENDS SINCE 2000 ?  IMPLICATIONS ? 3 , Vaccine Market North - South GAP Industrialised countries Developing countries Population BoD Vaccine sales 15% 85% 7% 93% 82% 18% 4 , VACCINE MARKET STRUCTURE 2010 World sales for drugs Vaccines US share Non- US Paediatric US Adult Small size market : 2/3% of the global pharmaceutical market but … Spectacular growth rate : 10 - 15% per year versus 5-7 % for Pharmaceuticals 5 , Vaccine segments Human vaccines Pediatrics Adolescents Adults Elderly 6 , GLOBAL VACCINE MARKET: RAPID GROWTH and CHANGING STATUS  Tripled in value from USD 5B in 2000 to almost USD 24 B in 2013 - Influenza vaccine market: estimated at $2.9 billion in 2011 to $3.8 billion by 2018 - US : $1.6 billion in 2011 to $2.2 ...
Children can usually get vaccinated if they have a mild common illness like a cold, ear infection, or diarrhea. Mild common illnesses do not interference with the immune response to vaccines and do not increase the risk of adverse events following immunization. Children taking antibiotics can also receive vaccines as antibiotics do not interfere with the immune response to the vaccine. If yo. Read Full Answer [field_profile_first_name] [field_profile_last_name] ...
SAFETY OF H1N1 VACCINE IN PREGNANT WOMEN :. H1N1 Vaccine have similar safety profiles of seasonal flu vaccine. Seasonal Flu Vaccines which are given to number of pregnant women for years with extreme safety. Hence we can consider H1N1 vaccination as safe to pregnant women.. SAFETY OF H1N1 VACCINE IN CHILDREN :. H1N1 Vaccine is considered to be very safe in children.During clinical trials, 10,000 to 15,000 children and adults have received various manufacturers brands of H1N1 swine flu vaccine. There is no serious side effects reported so far.. SAFETY OF THIOMERSAL IN H1N1 VACCINE. Thiomersal is a mercury based preservative that has been used in multi dose vials of most of the vaccines available in market. This compound act as a preservative which will prevent the growth of microorganism in vaccines. Use of thiomersal not have any direct impact on growth of children.. SAFETY OF SQUALENE IN H1N1 VACCINE Squalene is an ingredient of some vaccines to enhance immune responses which has been used in ...
Centers for Disease Control and Prevention. Vaccines are not just for infants. As kids get older, protection provided by some childhood vaccines can begin to wear off. Kids can also develop risks for more diseases as they enter their pre-teen years. Help your child transition into adolescence in a healthy way by staying up-to-date on pre-teen vaccines. Which Vaccines Do Pre-teens Need? Doctors recommend that all 11 and 12 year olds get the Tdap and meningococcal vaccines; 11- and 12-year-old girls should also get the human papillomavirus (HPV) vaccine.. Tdap vaccine This vaccine prevents pertussis, or whooping cough, which causes severe coughing fits. The coughing can cause pre-teens and teens to miss weeks of school, sports, and social activities. Parents may also have to miss work in order to take care of a sick child. Whooping cough is very contagious. It can be passed on to infants, who can die from it. Meningococcal conjugate vaccine (MCV4) This vaccine protects against meningitis and ...
J.B. provides vaccine facts that you can share with friends and neighbors who are concerned about safety. Thank you to CNNs Ali Velshi. To read the original Lancet paper and to learn more, please visit Generation Rescue.
J.B. provides vaccine facts that you can share with friends and neighbors who are concerned about safety. Thank you to CNNs Ali Velshi. To read the original Lancet paper and to learn more, please visit Generation Rescue.
Because taking health insurance away from millions of Americans isnt bad enough, President-elect Trump has reportedly asked an outspoken critic of vaccines - a
What are Adverse Events Following Immunization?. Any medical event occurring after immunisation can be classified as an adverse event following immunisation (AEFI) whether the event has any causal relationship to getting the immunisation or not. Adverse events/responses following immunisation can range from mild to severe and from common to very rare. They may occur as a result of the immunisation, a causal relationship between the event and immunisation, or occur after the immunisation by chance, a coincidental relationship between the event and immunisation.. *Please use the forms below to report an adverse event following immunization with any vaccine, including SARS-CoV-2 vaccines. ...
To evaluate the operation status of the adverse events following immunization(AEFI) surveillance system in Jiangsu Province in 2008.The description epidemiological methods were used in this study.6197 AEFI cases reported in 2008 were collected.The cases reaction were classified into vaccine reaction,its incidente is 98.97%,and coincidental,unknown and pending cases account for 0.95%,0.02% and 0.06%,respectively.Fever,absces in injection site and Dants scleroma are dominant clinical reaction of AEFI cases.The incidence rates of allergia rash and sterile abscess is rather higher than orthers.The operation status of AEFI Surveillance System is normal and the indicators are matched the requirements of MOH.Benefiting from the introduction of the standardized AEFI classification,case definition and direct network report,the data quality is being improved step by step.The safety of NIP vaccines and the quality of immunization services is satisfactory.
Objective: To assess the performance of SmartVax, a prototypic active monitoring system for adverse events following immunisation (AEFI) using short message service (SMS) text messages and clinical data extracted from commercially available medical practice management software. Design, setting and participants: Between 11 November 2011 and 10 June 2013, adult patients and parents of paediatric patients receiving routine vaccinations in general practice were sent an SMS by SmartVax enquiring if they had experienced any AEFI and requesting a reply by SMS. Attempts were made to telephone patients who did not reply by SMS. Main outcome measures: The proportion of patients sent an SMS who replied by SMS, and the proportion of respondents indicating possible AEFI. Results: Of 3281 vaccinated patients, 3226 (98.3%) had a mobile telephone number on record and were sent an SMS. Of 2342 patients (72.6%; 95% CI, 70.0%-75.1%) who responded by SMS, 264 (11.3%; 95 CI, 9.9%-12.7%) reported possible AEFI. The ...
The adverse events following immunisation surveillance aims to monitor vaccine and immunisation program safety and to detect population-specific, rare, late-onset or unexpected adverse events that may not be detected in pre-licensure vaccine trials. This report provides an update on date for 1 January to 30 June 2011.
This report summarises national passive adverse events following immunisation (AEFI) surveillance data for children aged less than 7 years who received vaccines between 1 January and 30 June 2008 and is a supplement to the annual reports for each year.
This report summarises Australian passive surveillance data for adverse events following immunisation (AEFI) reported to the Therapeutic Goods Administration (TGA) for 2013. It also describes reporting trends over the 13-year period 1 January 2000 to 31 December 2013.
This report summarises Australian passive surveillance data for adverse events following immunisation (AEFI) for 2005, and describes reporting trends over the six year period 2000 to 2005.
28. Menzies R, Mahajan D, Gold MS, Roomiani I, McIntyre P, Lawrence G. Annual report: Surveillance of adverse events following immunisation in Australia, 2008. Commun Dis Intell. 2009;33:365-81. Available from: cdi3304 29. Mahajan D, Roomiani I, Gold MS, Lawrence GL, McIntyre PB, Menzies RI. Annual report: Surveillance of adverse events following immunisation in Australia, 2009. Comm Dis Intell. 2010;34:259-76. Available from: /cdi3403-1 30. Slade BA, Leidel L, Vellozzi C, Woo EJ, Hua W, Sutherland A, et al. Postlicensure safety surveillance for quadrivalent human papillomavirus recombinant vaccine. JAMA. 2009;302:750-7. 31. Medicines and Healthcare productsRegulatory Agency (MHRA). Paper provided by MHRA for Joint Committee on Vaccination and Immunisation June 2009: Vaccine associated suspected adverse reactions reported via the Yellow Card scheme during 2008 [cited 2011 ...
Vaccines have been one of the most successful public health interventions to date with most vaccine-preventable diseases having declined in the United States by at least 95-99%. However, vaccines are pharmaceutical products that carry risks. They interact with the human immune systems and could permanently alter gene molecular structures. Under the National Childhood Vaccine Injury Act of 1986, over $2 billion has been awarded to children and adults for whom the risks of vaccine injury were 100% [1]. Potential relationships between vaccines and particular vaccine adverse events (VAE) may exist, but not well studied yet. The U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) is a national vaccine safety surveillance program for post-vaccination adverse events (AE) that occur after the administration of vaccines licensed in the United States [2]. Currently the VAERS contains more than 200,000 reports in total. Patients or healthcare providers submit reports about cases of adverse events ...
This report published in Communicable Diseases Intelligence Volume 24, No 2, 17 February 2000 contains information on the the Measles Control Campaign, which was conducted in Australia from August to November 1998 and resulted in a total of 1.7 million school children being vaccinated.
While previous studies have validated vaccine hesitancy scales with uptake behavior at the individual level, the conditions under which aggregated survey data are useful are less clear. We show that vaccine public opinion data aggregated at the subnational level can serve as a valid indicator of aggregate vaccine behaviour. We use a public opinion survey (Eurobarometer EB 91.2) with data on vaccine hesitancy for the EU in 2019. We link this information to (subnational) regional immunization coverage rates for childhood vaccines - DTP3, MCV1, and MCV2 - obtained from the WHO for 2019. We conduct multilevel regression analyses with data for 177 regions in 20 countries. Given the variation in vaccine hesitancy and immunization rates between countries and within countries, we affirm the valuable role that surveys can play as a public health surveillance tool when it comes to vaccine behavior. We find statistically significantly lower regional vaccine immunization rates in regions where vaccine ...
GACVS considered recent data on the safety profile of live attenuated SA 14-14-2 JE vaccine, provided in a number of expert presentations to the Committee. Live attenuated SA 14-14-2 JE vaccine constitutes more than 50% of the global production of all JE vaccines. The anticipated global demand for JE vaccine in 2012 is expected to exceed the present requirement twofold. Even though several new vaccine candidates are in development, their production and distribution remain uncertain for the time being. The current production of live attenuated SA 14-14-2 vaccine exceeds 50 million doses annually, most of which are used in China. Neuroattenuation of the virulent JE SA 14-14-2 strain is reported to be based on 57 nucleotide changes and 24 amino acid substitutions, suggesting that reversion to neurovirulence of the vaccine strain would be highly unlikely. Vaccine production is in accordance with WHO technical specifications, including detailed screening for adventitious viruses. Data reported from ...
If you are searching for the term Vaccine Injury Table, you may be looking for information about the National Vaccine Injury Compensation Program (NVICP). The NVICP is a federal program which compensates persons who experience a Vaccine Injury, which occurs when a child or adult experiences certain adverse reactions after receiving one of several vaccinations covered under the NVICP.. Claims for compensation to the NVICP are made to the U.S. Court of Federal Claims located in Washington, D.C., by filing a petition. Most petitioners are represented by lawyers. An attorney representing a petitioner must be admitted to practice in the U.S. Court of Federal Claims. The Vaccine Injury Table refers to a chart listing the most common vaccines or immunizations administered, such as DTaP vaccine, MMR vaccine, varicella (chicken pox) vaccine, and polio vaccine for children, the human papillomavirus (HPV) vaccine (Gardasil) for adolescents and young adults, tetanus/diphtheria/pertussis booster ...
Oduwoles presentation was entitled Investigating vaccine hesitancy and validating a measuring tool in the Western Cape Province. Her study looks at understanding some of the reasons for vaccine hesitancy in the Western Cape and aims to answer three questions: (1) What are the major causes and drivers of vaccine hesitancy in the province? (2) What measuring tools exist? And (3) are the survey tools valid in the context and setting.. Oduwole pointed out that there are currently vaccines available for 25 vaccine-preventable diseases, of which 13 are routinely administered in South Africa in accordance with the Expanded Programme on Immunisation. Vaccination progress in many countries have stalled or regressed in recent years due to a number of reasons. These include issues to do with resource constraints such as missed opportunities for vaccination; vaccine stock-outs and programme and infrastructural challenges; and issues to do with personal choice and vaccine hesitancy.. The Western Cape is ...
Yes, allergic reactions can happen, but they occur very rarely with the flu vaccines available in the United States today. Occasional cases of anaphylaxis, a severe life-threatening reaction that involves multiple organ systems and can progress rapidly, in egg-allergic persons have been reported to the Vaccine Adverse Event Reporting System (VAERS) after administration of flu vaccine. Flu vaccines contain various components that may cause allergic reactions, including anaphylaxis. In a Vaccine Safety Datalink study, there were 10 cases of anaphylaxis after more than 7.4 million doses of inactivated flu vaccine, trivalent (IIV3) given without other vaccines, (rate of 1.35 per one million doses). Most of these cases of anaphylaxis were not related to the egg protein present in the vaccine. CDC and the Advisory Committee on Immunization Practices continue to review available data regarding anaphylaxis cases following flu vaccines.. ...
All countries considered by the Review have a national passive AEFI surveillance system, but there are differences in the ways the systems are structured and administered. At the global level and in most countries, AEFI reporting is included in the general medicines adverse event reporting system. In the USA and in Canada, AEFIs are reported to a specific system for vaccines. The USA system is called the Vaccine Adverse Event Reporting System (VAERS). The database is held by the Department of Health and Human Services and jointly managed by two of the Departments agencies, the FDA and the CDC. In Canada, the system is called the Canadian Adverse Events Following Immunization Surveillance System (CAEFISS). It is currently administered by the Vaccine Safety Unit (VSU) of the Centre for Immunization and Respiratory Diseases (CIPD) of the Public Health Agency of Canada (PHAC). The Canadian system has a specific committee, the Advisory Committee on Causality Assessment (ACCA), with broad-based ...
While vaccines help prevent many diseases in the United States, we lack immunization protection against several serious illnesses, says a new report from the Institute of Medicine that identifies priority areas for updating the National Vaccine Plan. The revised plan should include a strategy to accelerate development of high-priority vaccines, said the committee that wrote the report. In addition, it should emphasize the importance of expanding funding for safety research and monitoring, and include the development of a national communications strategy to clarify the importance of vaccines and bolster public confidence in the immunization system.. The National Vaccine Plan aims to provide centralized coordination of the various components involved in protecting Americans from vaccine-preventable illnesses and vaccine-related adverse reactions. The immunization system engages many partners -- including multiple government agencies and departments, vaccine researchers, manufacturers, public ...
The writer has become embroiled in the controversy about whether or not it is wise to vaccinate.. I have been encountering cases of vaccine injury for over 40 years. In June it was a happy, healthy nearly 5-year-old whose parents were required to put her on a catch-up schedule, in order to get her into kindergarten. She wont be going to kinder. Shes in a wheel-chair, brain-damaged. Her life ruined. Then came a friends father who died after a flu vaccine, and last week a 4 year old boy, made autistic by a catch-up schedule.. In 1988, the US National Vaccine Injury Compensation Program was created. It has paid out over US$3.5 billion to the vaccine-injured. The NVICP was set up to protect vaccine manufacturers from ruinous costs of litigation by vaccine-damaged people. It was deemed preferable to have unavoidably unsafe vaccines than no vaccines. Unfortunately the protection provided to vaccine manufacturers also reduced incentives to develop safer vaccines in USA.. Politicians and doctors ...
The issue of vaccine safety in France received renewed media coverage in April following a report by the countrys Technical Committee of Pharmacovigilance to the Directorate General of Health regarding the deaths of two newborn babies from intussusception in 2012 and 2014 after receiving the Rotarix and RotaTeq vaccines.4 Intussusception is a serious disorder in which part of the intestine slides into an adjacent part of the intestine.5 The oral vaccines, produced by GlaxoSmithKline (GSK) and Merck respectively, have also been reported to have caused 500 adverse events-200 of which have been designated as serious.4 ...
Participate in the international vaccine conference and learn about childhood vaccine safety, public vaccination and vaccine safety information provided on NVIC.
H 845.1 I61b 2011 c.2 Intervals between Live Vaccines and Other Rules All vaccines can be administered simultaneously (on the same day). 2 Live Vaccines Live vaccines can be given on the same day. If they are not given on the same day, they should be separated by a minimum 4-week interval, because the immune response to one of the vaccines might be impaired. If two live vaccines are not given on the same day and are given less than four weeks apart, the second vaccine should be repeated. Alternatively, the effectiveness of the second vaccine can be checked by serologic testing. H Dont do this less than 4 weeks at least 4 weeks This applies to MMR, varicella, zoster, yellow fever vaccines & LAIV; but, it does not apply to oral typhoid and rotavirus vaccines. Inactivated vaccines do not interfere with live vaccines and live vaccines do not interfere with inactivated vaccines. An inactivated vaccine can be administered either simultaneously or at any time before or after a different inactivated or ...
As I reported in my column, the one exception to this drumbeat of misleading and inaccurate coverage about vaccine safety is on the local level, where correspondent Michael Chen of ABC 10 News in San Diego, California noted a case of a boy who suffered serious injuries, including fever, seizures, nervous tics and autism, as a result of two vaccines. The mother, almost in tears as she described what happened to her son, was paid $55,000 in damages through the federal program. But the damage award didnt cover the autism diagnosis. She said she wished she had more thoroughly researched the safety of vaccines.. The National Vaccine Injury Compensation Program grew out of the 1986 National Childhood Vaccine Injury Act. Fisher explains what happened: The companies threatened Congress that they were going to leave the people without any childhood vaccines if they did not get liability protection. The companies wanted this liability protection and it was mainly for losses at that time for DPT and ...
Surveillance and developments in 2016-2017 In 2016, about 760,000 children aged 0 to 19 years received a total of 2,140,000 vaccinations within the National Immunisation Programme (NIP). Participation in the NIP was high (more than 90% depending on the vaccine), but dropped by around 0.5% for newborns for the third consecutive year. The participation in vaccinations against human papillomavirus (HPV) declined from 61 to 53 per cent. The number of reports (1,483) of adverse events following immunisation (in total 3,665) in 2016 was comparable to the number of reports in 2015. NIP target diseases The number of reported cases of most NIP target diseases was again low. However, the number of cases of Haemophilus influenzae type b (Hib) disease in 2016 (n=44) was considerably higher than in the previous five years (22-34 cases), with the highest incidence occurring among children under five years of age. Pertussis incidence in 2016 fits within the usual fluctuations. However, six people died from ...
I never really questioned vaccine safety and I thought I understood the reasoning of why vaccines worked. I had been in a pre-med curriculum in my undergraduate study and my children were vaccinated in the 1980s when they were young. I was a practicing R.N. for many years and I received a number of vaccines during that time and I administered many. I was injured by the Hep B vaccine series in 1992-93, but no one was very interested in reporting or tracking that injury. I began studying vaccination in 2009 when I was out on a disability leave of absence.. There is an explosion of vaccine related injuries occurring across our country. There is something very, very wrong happening to our children; many are suffering from allergies, neurological and immune-system damage. In 1986 the National Childhood Vaccine Injury Act was passed where The National Vaccine Injury Compensation Board was formed by Congress at the bequest of the vaccine manufacturers because they were being inundated with lawsuits ...
Dr. James R. Shannon, former Director of the US National Institute of Health, has been widely quoted as saying: The only safe vaccine is one that is never used. But are adverse vaccine reactions really a big deal? Arent they just the fever and fatigue were warned about after yearly shots? Or is there more to learn?. And arent moderate and severe adverse reactions rare? Lets answer this question first.. Reactions are considered rare, in part, because reporting is rare. Unlike reporting for human vaccine reactions, required by the National Vaccine Injury Act of 1986, reporting is voluntary for reactions experienced by animals. Furthermore, there is no federal Vaccine Adverse Event Reporting System (VAERS) for animals as there is for humans, nor is there a National Vaccine Injury Compensation Program (VICP). That does not mean that adverse events arent a serious a problem for animals. In fact, because animals are given numerous vaccines repeatedly (and unnecessarily) throughout their ...
Dr. James R. Shannon, former Director of the US National Institute of Health, has been widely quoted as saying: The only safe vaccine is one that is never used. But are adverse vaccine reactions really a big deal? Arent they just the fever and fatigue were warned about after yearly shots? Or is there more to learn?. And arent moderate and severe adverse reactions rare? Lets answer this question first.. Reactions are considered rare, in part, because reporting is rare. Unlike reporting for human vaccine reactions, required by the National Vaccine Injury Act of 1986, reporting is voluntary for reactions experienced by animals. Furthermore, there is no federal Vaccine Adverse Event Reporting System (VAERS) for animals as there is for humans, nor is there a National Vaccine Injury Compensation Program (VICP). That does not mean that adverse events arent a serious a problem for animals. In fact, because animals are given numerous vaccines repeatedly (and unnecessarily) throughout their ...
Reposted from World Vaccine Congress. What technology has had the biggest impact on vaccine supply chains over the last 10 years?. There is no magic bullet that has revolutionized vaccine supply chains over the last ten years. Instead, a range of technologies working in concert with one another have contributed to more effective and efficient supply chains. Developments in cold chain technology, data gathering and analytics, and even in transportation have all had significant impacts on the availability of vaccines. These technologies all must work in-sync with each other to provide both the infrastructure and information needed to ensure vaccines are available where and when they are needed and in the right condition. We must also ensure these technologies are appropriate and available at all levels of the supply chain. As a global community, we have greatly improved the systems, infrastructure and financing to ensure sufficient vaccines reach low-resource countries, but the real impact comes ...
Vaccines help make you immune to serious diseases without getting sick first. Without a vaccine, you must actually get a disease in order to become immune to the germ that causes it. Vaccines work best when they are given at certain ages. For example, children dont receive measles vaccine until they are at least one year old. If it is given earlier it might not work as well. The Centers for Disease Control and Prevention publishes a schedule for childhood vaccines.. Related Conferences: Children Vaccines 2016 Oct 10-12, 2016 Rome, Italy; International Conference on H1N1 & Influenza Vaccines July 25-26, 2016 Chicago, USA; International Conference on Hepatitis Vaccines Conference June 16-18, 2016 Rome, Italy; Annual Conference on Virulent Hiv Vaccines Conference Oct 3-5, 2016 Miami, USA; 10th Euro Global Summit and Expo on Vaccines & Vaccination 16-18, 2016 Rome, Italy; 13th Vaccines Asia Pacific Global summit and Expo on Vaccines & Vaccination Conference November 03-05, 2016 Melbourne, ...
The 16th Annual Conference on Vaccine Research, the largest scientific forum devoted exclusively to research and development of vaccines and related technologies for prevention and treatment of disease through immunization, will be held April 22-24, 2013, at the Hyatt Regency Inner Harbor Hotel in Baltimore, Maryland. The conference brings together the diverse fields of human and veterinary vaccinology to encourage collaboration and multidisciplinary approaches among methodologic experts and experts in specific diseases. Clinical developments in vaccine discovery, rotavirus, meningococcal vaccine, vaccines for enteric diseases, food safety vaccines, vaccine adjuvants, and adverse events are among topics scheduled for discussion during the conference. In addition, a preconference workshop, Creating Outstanding Scientific Communications: Talks, Abstracts, and Posters, will be offered by expert faculty. Applications for travel grants to subsidize attendees from countries with limited resources must ...
The Vaccine Adverse Event Reporting System (VAERS) was created by Congress under the National Childhood Vaccine Injury Act of 1986 and became operational in
Additional authors on this paper include: Bruce Fireman, MS, from the Kaiser Permanete Division of Research; Katherine Yih, MPH, PhD, from Harvard Pilgrim HealthCare Institute and Harvard Medical School, Boston, MA; Edwin Lewis, MPH, from the Kaiser Permanente Vaccine Study Center; Martin Kulldorff, PhD, from Harvard Pilgrim Healthcare Institute; Paula Ray, MPH, from the Kaiser Permanente Vaccine Study Center; Roger Baxter, MD, from the Kaiser Permanente Vaccine Study Center; Simon Hambridge, MD, PhD, from Kaiser Permanente, Denver, Co; James Nordin, MD, MPA, from Health Partners Research Foundation, Minneapolis, MN; Allison Naleway, PhD, Kaiser Permanente, Portland, OR; Edward A. Belongia, MD, from Marshfield Clinic Research Foundation; Tracy Lieu, MD, MPH, from Harvard Pilgrim Health Care Institute; James Baggs, PhD, from the Immunization Safety Office, CDC; Eric Weintraub, MPH, from the Vaccine Safety Datalink. Funding for the study was provided by the Vaccine Safety Datalink contract with ...
At the end of March 2010 an A/H1N1 vaccination campaign was conducted in Afghanistan using donated vaccines. However, no surveillance system for detection of adverse events following immunization was in place. We report a cross-sectional, descriptive survey in 4 provinces of Afghanistan to assess the rate of adverse events among health care staff immunized with A/H1N1 monovalent vaccine 4 weeks after vaccination. Using random sampling proportionate to size, 350 staff [‎mean age 36 years, range 16-65 years]‎ were surveyed using a questionnaire. The highest self-reported rates of adverse events were pain at the injection site [‎53%]‎, fever in the first 3 days after immunization [‎40%]‎, body pain [‎39%]‎, tiredness [‎33%]‎, swelling at the injection site [‎29%]‎ and redness at the injection site [‎28%]‎. More females than males suffered adverse reactions and the rates varied across different provinces, ranging from 79% in Balkh to 23% in ...
The history of immunisation can be traced through two major narratives. The first is a story of profound benefit to global health, the other a complex tale of risk and uncertainty versus safety and public confidence. These narratives are forever intertwined, not least because as successful immunisation programmes lead to progressive reductions in disease risk, so the prospect of adverse vaccine-related events becomes a dominant public concern.. Anaphylaxis has long been recognised as a rare but serious complication of vaccination, but despite millions of infants and children receiving vaccine doses every year, data describing the incidence of anaphylaxis as an adverse event following immunisation (AEFI) are surprisingly sparse. Erlewyn-Lajeunesse et als prospective survey of anaphylaxis as an AEFI, published in this issue, provides a valuable addition to the existing evidence concerning vaccination safety.1. Serious allergic reaction in childhood sits alongside meningitis in the public ...
VAERS was established after Congress passed the National Childhood Vaccine Injury Act in 1986 requiring providers and vaccine manufacturers to report possible adverse events that occur during or following the administration of vaccines licensed in the United States. VAERS receives approximately 30,000 reports a year (Shimabukuro TT et al. Vaccine. 2015;30:4398). About 85% of VAERS reports describe mild adverse events such as fever or local reactions. Which three of the following statements are true:. a) An adverse reaction is defined as any side effect, injury, toxicity or sensitivity reaction, or failure of pharmacologic action. b) An adverse reaction occurring after vaccine administration does not need to be reported if it is considered to be unrelated to the vaccine. c) Serious adverse events include death, life-threatening conditions, hospitalization, permanent disability, congenital anomaly or impairment of a body function. While these events may occur after vaccination, they rarely are ...
A definitive and readable reference guide to the world of vaccines!The Vaccine Book provides concrete information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. The Vaccine Book is designed to increase the understanding of vaccines for students, researchers, public health officials, and all others working to address such challenges. Topics unique to this book:* Ethics * Economics * Diseases that could be prevented* Clinical trial designs* Ideas about the future of vaccines* Challenges facing research scientists in the vaccine area* Burden of vaccine-preventable illness and the impact of vaccines* Scientific
It sounds reasonable, it sounds nice. But dont hold your breath. The CDC is hardly issuing engraved invitations to come trawl its mainframes, despite a harshly written report earlier this year from the Institute of Medicine. The IOM complained of CDC foot dragging, and even insolence, on this matter, and suggested that vaccine officials at the health agency seek legal counsel. Why? Because the original datasets of children used by the government have, as they say, gone missing. (Actually, the official explanation was that they were not archived in a standard fashion.) The intentional loss or destruction of taxpayer funded data or datasets is a violation of the Federal Data Quality Act. It is a felony, and someone could go to jail for it ...
Vaccines have been one of the most successful public health interventions to date. The use of vaccination, however, sometimes comes with possible adverse events. The U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) currently contains more than 200,000 reports for post-vaccination events that occur after the administration of vaccines licensed in the United States. Although the data from the VAERS has been applied to many public health and vaccine safety studies, each individual report does not necessarily indicate a casuality relationship between the vaccine and the reported symptoms. Further statistical analysis and summarization needs to be done before this data can be leveraged. This paper introduces our efforts on representing the vaccine-symptom correlations and their corresponding meta-information extracted from the VAERS database using Resource Description Framework (RDF). Numbers of occurrences of vaccine-symptom pairs reported to the VAERS were summarized with corresponding
Therapeutic vaccines function by triggering a body immune response against a disease. The global therapeutic vaccines market was valued at USD 292 million in 2011. The introduction of therapeutic vaccines has opened up new avenues in the field of chronic disease treatment and prophylactic immunization. Provenge was the first U.S. FDA approved immunotherapy drug to treat prostate cancer in men in 2010, which has encouraged rigorous research and development initiatives by pharmaceutical companies to develop novel vaccines for untapped disease segments. As a result of these initiatives, many more therapeutic vaccines are currently in the pipeline such as breast cancer vaccine, lung cancer vaccine; Alzheimers vaccine, malaria vaccine, and diabetes vaccine are expected to be introduced in the market during the period from 2012 to 2018. ...
According to the latest report Vaccines Market: By Type (Monovalent, Multivalent); By Technology (Conjugate Vaccines, Inactivated and Subunit Vaccines, Others); By Disease Indication (Pneumococcal Disease, DTP, Others); By End User (Paediatrics, Adults) & Region-Forecast (2016-2022), published by IndustryARC, estimates that Asia-Pacific will register the fastest growth over the forecast period.. Browse Market Report @ Vaccine is a biological preparation that is used for prevention of infectious diseases. The vaccination saves provides better and healthier life to millions of lives including adults, children and animals. World Health Organization and many other international organizations had approved the vaccination as the one of the bes methods for the prevention of infectious diseases. There are different kinds of vaccines present in the market like polio vaccine, rubella vaccine, chickenpox vaccine, TB vaccine, yellow fever vaccine, ...
According to the latest report Vaccines Market: By Type (Monovalent, Multivalent); By Technology (Conjugate Vaccines, Inactivated and Subunit Vaccines, Others); By Disease Indication (Pneumococcal Disease, DTP, Others); By End User (Paediatrics, Adults) & Region-Forecast (2016-2022), published by IndustryARC, estimates that Asia-Pacific will register the fastest growth over the forecast period.. Browse Market Report @ Vaccine is a biological preparation that is used for prevention of infectious diseases. The vaccination saves provides better and healthier life to millions of lives including adults, children and animals. World Health Organization and many other international organizations had approved the vaccination as the one of the bes methods for the prevention of infectious diseases. There are different kinds of vaccines present in the market like polio vaccine, rubella vaccine, chickenpox vaccine, TB vaccine, yellow fever vaccine, ...
The Indian Academy of Pediatrics has called for doctors working in the private sector to report adverse events after immunisations to the national surveillance system to ensure more complete vaccine safety data. In a position paper published in Indian Pediatrics, the academy said that the adverse event following immunization (AEFI) surveillance system run by the government needed to be strengthened by including reports from the private sector.1. India has one of the largest universal immunisation programmes in the world, with 26 million babies born every year. Approximately … ...
The Vaccine Adverse Event Reporting System (VAERS), is a national program managed by the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Food and Drug Administration (FDA) to monitor the safety of all vaccines licensed in the United States. VAERS collects and reviews reports of adverse events that occur after vaccination. An adverse event is any health problem or side effect that happens after a vaccination. VAERS cannot determine if a vaccine caused an adverse event, but can determine if further investigation is needed ...
If smoking a cigarette no longer delivers pleasure, will smokers quit? Its the idea behind a nicotine vaccine being created by MIT and Harvard researchers, in which an injection of synthetic nanoparticles prompts the immune ...
"Q&a The Vaccines' Justin Young - on new album The Vaccines Come of Age, why "clunky lyrics" rule, the need to make an emotional ... Official website The Vaccines' BBC Sound of 2011 page at BBC Online The Vaccines Celebrate a Decade of Debut Album 'What Did ... The Vaccines - Come of Age,, 27 July 2012. "The Vaccines Announce Details of 2013 London O2 Arena Show And New ... "The Vaccines Post Covers EP , News , Clash Magazine". Retrieved 20 October 2013. "The Vaccines - What Did You ...
A therapeutic vaccine differs from a prophylactic vaccine in that prophylactic vaccines are administered to individuals as a ... The specific type of therapeutic vaccines include antigen vaccines. In case of antigen vaccines, the body is introduced to a ... vaccine) to train them to differentiate and fight cancer cells. Therapeutic vaccines are a new form of vaccines that are mostly ... HIV has no vaccine up until now, but therapeutic vaccines could be the breakthrough for HIV. Such vaccines would enhance ...
... , also called autologous vaccines, autovaccines, "self" or custom vaccines, are vaccines that are prepared ... including autogenous vaccines. Vaccine Therapeutic vaccines Immune system Immunotherapy Giedrys-Kalemba S, Czernomysy-Furowicz ... Autogenous vaccines have been researched since as early as the 1900s. This type of vaccine was first introduced by Sir Almroth ... Autogenous vaccines are also a good and quick alternative when there are no vaccines for a novel emerging disease or a ...
... tuberculosis-based vaccine to enter clinical trials". Vaccine. 31 (42): 4867-4873. doi:10.1016/j.vaccine.2013.07.051. PMID ... Vaccine development is proceeding along several paths:[citation needed] Development of a new prime vaccine to replace BCG ... "Antituberculous Vaccine Development: A Perspective For The Endemic World." Expert Review of Vaccines 8.11 (2009): 1547-1553. ... Today, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin (BCG) vaccine, first used on ...
"VBI Vaccines Announces Initiation of Enrollment in Adaptive Phase 1/2 Study of Prophylactic COVID-19 Vaccine Candidate, VBI- ... "Variation Biotechnologies Secures $35.7M in Series A Financing to Fund Innovative Vaccine Platform". VBI Vaccines. January 4, ... COVID-19 vaccine producers, All stub articles, COVID-19 vaccine stubs, COVID-19 pandemic stubs, Canadian company stubs, United ... In August VBI received CA$56 million from the Government of Canada to prepare its vaccine for clinical trials by the end of ...
New third-generation vaccines being researched include recombinant live vaccines and recombinant sub-unit vaccines. In the ... Anthrax vaccines are vaccines to prevent the livestock and human disease anthrax, caused by the bacterium Bacillus anthracis. ... These vaccines may be given by aerosol, scarification, or subcutaneous injection. A Georgian/Russian live anthrax spore vaccine ... This was a cell-free vaccine in distinction to the live-cell Pasteur-style vaccine previously used for veterinary purposes. It ...
... in Leiden developed the COVID-19 vaccines for Johnson & Johnson. Initial production of the vaccine is ... The vaccine stands out because it is the first single-shot vaccine against COVID-19 that was developed during the COVID-19 ... Swedish SBL Vaccines and US-based Berna Products joined forces to become the sixth largest vaccine company worldwide, with ... "Janssen Vaccines AG". Company Profiles. Bloomberg. 2020. (Articles with short description, Short description matches Wikidata, ...
"No, a Vaccine Court ruling does not show that vaccines cause SIDS". Science-Based Medicine. 2017-08-21. Retrieved 2019-02-01. ... A speculated link between vaccines and SIDS has been refuted, but remains a common anti-vaccine claim. The claim, attributed to ... "Sudden Infant Death Syndrome (SIDS) and Vaccines". U.S. Center for Disease Control and Prevention. Vaccines have not been shown ... is that vaccines, especially the DTP vaccine that protects against diphtheria, tetanus and pertussis, sometimes causes sudden ...
... is a monthly peer-reviewed medical journal covering research into vaccines and ... It was established in 2005 as Human Vaccines, and obtained its current name in 2012. It is published by Taylor & Francis and ... "Human Vaccines & Immunotherapeutics". 2013 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2014. ...
... parental concerns about vaccine 'overload' and 'immune-vulnerability'". Vaccine. 24 (20): 4321-7. doi:10.1016/j.vaccine.2006.03 ... Vaccine. 36 (39): 5825-31. doi:10.1016/j.vaccine.2018.08.036. PMID 30139653. S2CID 52073320. "Vaccines, Autism, and Retraction ... Vaccine overload became popular after the Vaccine Injury Compensation Program accepted the case of nine year old Hannah Poling ... Vaccine burden: Miller E, Andrews N, Waight P, Taylor B (March 2003). "Bacterial infections, immune overload, and MMR vaccine. ...
"The Vaccines Premiere the Video For "Dream Lover"". NOISEY. "The Vaccines have dropped a brand new video for 'I Can't Quit'". ... "The Vaccines - 'Wreckin' Bar (Ra Ra Ra)' - Music Video". MTV. Retrieved 6 June 2012. "The Vaccines - 'Post Break-Up Sex' - ... Type Vaccines in the "Search BPI Awards" field and then press Enter. "The Vaccines - Chart History: Heatseekers Albums". ... Melody Calling' - The Vaccines. Vimeo. "The Vaccines - see the video for their new single Handsome". The Guardian. Retrieved 21 ...
CDC PUBLISHES THIMEROSAL IN VACCINES Notice to Readers: Thimerosal in Vaccines Baker JP (2008). "Mercury, Vaccines, and Autism ... including the Hib vaccine, DTaP vaccine and hepatitis B vaccine, could have contained thiomersal. Third, the number of ... but vaccine advocates doubt their utility given the lack of evidence for danger with thiomersal in vaccines. Vaccine advocates ... Second, the vaccine schedule for infants expanded in the 1990s to include more vaccines, some of which, ...
... partly due to international vaccine funders; in 2012, UNICEF bought half of the world's vaccine doses). Vaccines are becoming ... While vaccine research and development is done by many small companies, large-scale vaccine manufacturing is done by an ... Many vaccines have been highly cost effective and beneficial for public health. The number of vaccines actually administered ... Vaccines are newly being marketed like pharmaceuticals. Vaccines offer new opportunities for funding from public-private ...
The following vaccines are included in the VFC Program: * Vaccines initially targeted by the VFC program in 1994. ** Vaccines ... covers only certain vaccines, or does cover some vaccines, but has a cap on the annual cost for vaccines*. Underinsured ... The Vaccines for Children Program (VFC) is a federally funded program in the United States providing no-cost vaccines to ... The Vaccines for Children program represented a major vaccine finance reform, working as a state-operated federal entitlement ...
Regulation of vaccines in developing countries". In Plotkin, Stanley A.; Orenstein, Walter A.; Offit, Paul A. (eds.). Vaccines ... The List of Prequalified Vaccines, published by the World Health Organization, lists vaccines that are found to be safe, ... ISBN 978-92-4-156386-4. "List of Prequalified Vaccines". WHO - Prequalification of Medical Products (IVDs, Medicines, Vaccines ... Maurice, J. M.; Davey, Sheila; Organization, World Health (2009). "2. A new chapter in vaccine development". State of the ...
Cytomegalovirus vaccine Epstein-Barr virus vaccine Hepatitis C vaccine Herpes simplex vaccine HIV vaccine Respiratory syncytial ... First oral polio vaccine (Sabin vaccine) 1963 - First vaccine for measles 1967 - First vaccine for mumps 1970 - First vaccine ... First vaccine for malaria 2015 - First vaccine for dengue fever 2019 - First vaccine for Ebola approved 2020 - First vaccine ... First vaccine for tick-borne encephalitis 1952 - First vaccine for polio (Salk vaccine) 1954 - First vaccine for Japanese ...
"Expert Review of Vaccines Publishes Special Issue on Vaccines for Biodefense!". Taylor & Francis. 21 September 2016. Retrieved ... making it the highest-impact journal dedicated specifically to vaccines. "Expert Review of Vaccines". 2015 Journal Citation ... Expert Review of Vaccines is a monthly peer-reviewed medical journal covering all aspects impacting the clinical effectiveness ... of vaccines. According to the Journal Citation Reports, the journal has a 2015 impact factor of 4.222, ...
The subgroup of genetic vaccines encompass viral vector vaccines, RNA vaccines and DNA vaccines. Viral vector vaccines use a ... Examples include IPV (polio vaccine), hepatitis A vaccine, rabies vaccine and most influenza vaccines. Toxoid vaccines are made ... RNA vaccines and DNA vaccines are examples of third generation vaccines. In 2016 a DNA vaccine for the Zika virus began testing ... Vaccine cooler Vaccine failure Vaccine hesitancy Vaccinov Viral vector Virus-like particle Nasal vaccine "Expanded Practice ...
The Vaccines Manufacturing and Innovation Centre (VMIC) is a vaccine research and manufacturing facility under construction in ... "New vaccines centre to protect UK from pandemic threats". University of Oxford. 3 December 2018. Retrieved 22 March 2021.{{cite ... "Vaccines Manufacturing and Innovation Centre to open 12 months ahead of schedule". GOV.UK. Retrieved 17 January 2021. " ... In 2020, the centre's personnel contributed to development of the Oxford-AstraZeneca COVID-19 vaccine AZD1222, and from October ...
... rVSV vaccines) are vaccines made using recombinant Indiana vesiculovirus. rVSV vaccines include: rVSV-ZEBOV vaccine against ... rVSV-MARV vaccine, a candidate against the Marburg virus (development discontinued for business reasons) rVSV-based vaccine ... This disambiguation page lists articles associated with the title Recombinant vesicular stomatitis virus vaccines. If an ... Ebola rVSV-SUDV vaccine, a candidate against Sudan ebolavirus (development discontinued for business reasons) ...
"Bad Mood" is a song from English indie rock band the Vaccines. The track was released in the United Kingdom on 17 March 2013 as ... The Vaccines songs, All stub articles, 2010s rock song stubs). ... "The Vaccines - Bad Mood" (in Dutch). Ultratip. v t e (Articles ...
"The Vaccines premiere new song 'Dream Lover' from English Graffiti". Digital Spy. Retrieved 6 June 2015. "The Vaccines - Dream ... "Dream Lover" is a song from English indie rock band the Vaccines. The track was released in the United Kingdom on 18 May 2015 ... "Huw Stephens - Leon Bridges + The Vaccines + Madeon". BBC Radio 1. Retrieved 6 June 2015. " ... The Vaccines songs, Columbia Records singles, All stub articles, 2010s rock song stubs). ...
Vaccine. 35 (17): 2115-2120. doi:10.1016/j.vaccine.2016.11.097. PMID 28364918. "How can we make enough vaccine for 2 billion ... "vaccine nationalism" - threaten vaccine availability for poorer nations.[excessive citations] The RNA vaccines from Moderna and ... Vaccine. 35 (17): 2127-2133. doi:10.1016/j.vaccine.2016.09.070. PMID 28364920. "China's Sinopharm vaccine 86% effective, say ... 1.2 billion to secure 300 million vaccine doses for Americans, even before the AstraZeneca-Oxford vaccine or a Sanofi vaccine ...
... a pandemic flu vaccine H5N1 vaccine "Influenza vaccines - United States, 2019-20 influenza season*". U.S. Centers for Disease ... This vaccine is intended for people 65 and over, who typically have weakened immune response due to normal aging. The vaccine ... Novartis developed the first influenza vaccine, which did not need to be grown in chicken eggs, a cell-based vaccine. In 2014, ... "Fluzone intradermal vaccine website". Sanofi Pasteur. "FDA Approves A High Dose Seasonal Influenza Vaccine Specifically ...
All live vaccines studied so far (BCG, measles vaccine, oral polio vaccine (OPV) and smallpox vaccine) have been shown to ... "Sex differences in the vaccine-specific and non-targeted effects of vaccines". Vaccine. 29 (13): 2349-54. doi:10.1016/j.vaccine ... The negative effects are seen as long as DTP vaccine is the most recent vaccine. BCG or measles vaccine given after DTP ... This has been shown with two live attenuated vaccines, BCG vaccine and measles vaccine, through multiple randomized controlled ...
Inactivated vaccines, Vaccines, World Health Organization essential medicines (vaccines), Wikipedia medicine articles ready to ... The first vaccines used against cholera were developed in the late 1800s. They were the first widely used vaccine that was made ... The first cholera vaccine developed by Louis Pasteur was on chicken and other animals. They were the first widely used vaccine ... His vaccine was accepted by the medical community, and is credited as the first effective human cholera vaccine. Finally, in ...
... standalone vaccine) Measles and rubella combined vaccine (MR vaccine) Mumps, measles and rubella combined vaccine (MMR vaccine ... a combination with the rubella vaccine and mumps vaccine) or the MMRV vaccine (a combination of MMR with the chickenpox vaccine ... MMRV vaccine) Most health insurance plans in the United States cover the cost of vaccines, and Vaccines for Children Program ... Live vaccines, Measles, Vaccines, World Health Organization essential medicines (vaccines), Wikipedia medicine articles ready ...
... is a delay in acceptance, or refusal, of vaccines despite the availability of vaccine services. The term ... when the routine vaccine schedule could contain more than 3,000 antigens (in a single shot of DTP vaccine). The vaccine ... the more vaccines offered, the higher the likelihood of vaccine deferral). The use of combination vaccines to protect against ... the person does not see a need for the vaccine or does not see the value of the vaccine), and convenience (access to vaccines ...
... is a lack of immunity, or immunologic memory, to a disease because the person has not been vaccinated. There are ... Vaccine-naive persons threaten what epidemiologists call herd immunity. This is because vaccinations provide not just ... Wallace, H. Shortages require practices to take extra measures to keep patients up-to-date on vaccines: Calling the shots. AAP ... Garnett, G. P. (2005). "Role of Herd Immunity in Determining the Effect of Vaccines against Sexually Transmitted Disease". The ...
... , also known as chickenpox vaccine, is a vaccine that protects against chickenpox. One dose of vaccine ... Vaccine. 28 (13): 2532-2538. doi:10.1016/j.vaccine.2010.01.036. PMID 20117265. "CDC - Varicella Vaccine - Vaccine Safety". ... The vaccine is available either by itself or along with the MMR vaccine, in a version known as the MMRV vaccine. It is made ... Another vaccine, known as zoster vaccine, is simply a larger-than-normal dose of the same vaccine used against chickenpox, and ...
The vaccines do not cause infection in pregnant people or babies. ... getting COVID-19 vaccine can protect from severe illness from COVID-19. ... Children, teens, and adults, including pregnant people, may get a COVID-19 vaccine and other vaccines, including a flu vaccine ... Which COVID-19 vaccine should pregnant people receive? You can choose to get either an mRNA COVID-19 vaccine (Moderna or Pfizer ...
MMR vaccine may be given at the same time as other vaccines. Children 12 months through 12 years of age might receive MMR ... The National Vaccine Injury Compensation Program. The National Vaccine Injury Compensation Program (VICP) is a federal program ... Vaccine Information Statement. MMR Vaccine. (8/6/21). 42 U.S.C. § 300aa-26 ... MMR vaccine can prevent measles, mumps, and rubella. *MEASLES (M) causes fever, cough, runny nose, and red, watery eyes, ...
Hepatitis B vaccine: Vaccine can be administered with an accelerated schedule of 4 doses of vaccine given at 0, 1, 2, and 12 ... Polio vaccine: Polio vaccine is recommended for travelers to countries with evidence of wild poliovirus (WPV) or vaccine- ... typhoid vaccine will temporarily stop making and selling this vaccine. The vaccine may be in limited supply or unavailable. If ... Rotavirus vaccine is unique among the routine vaccines given to US infants because it has maximum ages for the first and last ...
Use your smartphone to report any side effects after getting any vaccine dose to v-safe. ... Vaccine Safety Monitoringplus icon *Vaccine Adverse Event Reporting System (VAERS). *CISAplus icon *CISA Resources for ... V-safe for COVID-19 Vaccines Data. You can view v-safe for COVID-19 vaccines public data here: v-safe , Data , Centers for ... Vaccine Safety Datalink (VSD)plus icon *Accessing Data from Vaccine Safety Datalink ...
CDCs Vaccines and Immunizations web site HOME PAGE. ... Product Info by US Vaccineplus icon *Pfizer-BioNTech Vaccine. * ... Vaccine Recipient Educationplus icon *How to talk to your patients about COVID-19 vaccination ...
... up-to-date and reliable information about vaccines to parents and healthcare professionals. ... The Vaccine Education Center at Childrens Hospital of Philadelphia provides complete, ... Vaccine Newsletters VEC offers two newsletters that keep readers up-to-date on vaccine news, research and developments:. ... The Vaccine Education Center provides accurate, comprehensive and up-to-date information about vaccines to parents and ...
Consent of applicants/manufacturers of a vaccine or a pharmaceutical product,. diagnostics and vaccines for WHO to share ... Vaccines are undoubtedly the most complex medical products to develop, from concept to a stage where sufficient evidence of ... Considerations for evaluation of COVID-19 vaccines for listing by WHO (Revised). *Appendix - considerations for evaluation of ... Roadmap for evaluation of AstraZeneca ADZ122 vaccine against COVID-19. Roadmap for evaluation of Jansen Ad26.COV2-S ( ...
... and Hispanic Americans in the study were least responsive to the vaccine. The findings appear in the journal Vaccine. ... "That may mean adjusting doses for some or being able to treat larger populations with the same vaccine if the dosage is less." ... "The significance of the findings is that in the future we may be able to create vaccines for specific groups or even ... "We dont know why these groups reacted so differently to the vaccine - thats a subject for further studies - but this new ...
Johnson vaccine were shipped Sunday night and could be used for injections as early as Tuesday, officials said. ... The J&J vaccine is only one dose, compared to the vaccines developed by Moderna and Pfizer - which require two doses for full ... How COVID-19 vaccine makers would adapt to new variants. New coronavirus variants have cropped up in the U.S.and vaccine makers ... In addition, this vaccine does not need to be kept in a freezer and can be stored at refrigerated temperatures - so it is easy ...
Vaccine. WHO EUL Holder. NRA of record. Date of EUL Recommendation COMIRNATY®. COVD-19 mRNA Vaccine (nucleoside modified). ... Covid-19 vaccine (Whole Virion Inactivated Corona Virus vaccine). Bharat Biotech International Ltd. Central Drugs Standard ... COVID-19 vaccine (SARS-CoV-2 rS Protein Nanoparticle [Recombinant]). Serum Institute of India Pvt. Ltd. Central Drugs Standard ... COVID-19 Vaccine (Ad5-nCoV-S [Recombinant]) CanSino Biologics Inc.. National Medical Products Administration (NMPA) 19 May 2022 ...
Vaccines to combat SARS-CoV-2, the virus that causes the disease, have been developed in record time. So far countries have ... leads our vaccine chart, having given first doses to its residents, although has delivered the most second doses. is currently ... of the worlds population have received at least one dose of a covid-19 vaccine. ...
... vaccine, including who can get a vaccine, how to book and how well the vaccine works. ... Valneva vaccine (not currently available). Which vaccine will I get?. You cannot usually choose which vaccine you have. If you ... Find out more about COVID-19 vaccine side effects and safety. COVID-19 vaccine ingredients. The COVID-19 vaccines do not ... You can find out about the ingredients in the vaccines currently available in the UK:. *Moderna (Spikevax) COVID-19 vaccine ...
Age-appropriate mRNA COVID-19 vaccines are preferred over the Janssen COVID-19 Vaccine for all vaccine doses for all vaccine- ... Globally, 12 vaccines are approved for full use, 21 vaccines are authorized for early or limited use, and 42 vaccines are in ... for Janssen vaccine products. [3] During this same time period, the Novavax vaccine showed 90.4% efficacy. [4] Vaccine efficacy ... Noninjectable Vaccine. Comments. hAd5 T-cell (ImmunityBio and NantKwest) [82] Vaccine targets inner nucleocapsid (N) and outer ...
This is the CBER Vaccines and Related Biological Products Advisory Committee September 17, 2021 Meeting Announcement. ... Vaccines and Related Biological Products Advisory Committee September 17, 2021 Meeting Voting Question 1. pdf (39.41 KB) FDA. ... Vaccines and Related Biological Products Advisory Committee September 17, 2021 Meeting Draft Agenda. pdf (81.32 KB) FDA. ... Vaccines and Related Biological Products Advisory Committee September 17, 2021 Meeting Draft Roster. pdf (174.95 KB) FDA. ...
Vaccines protect against life-threatening diseases. Follow a recommended immunization schedule to protect yourself and others ... What are the types of vaccines?. There are several types of vaccines:. *Live-attenuated vaccines use a weakened form of the ... What is a vaccine schedule?. A vaccine, or immunization, schedule lists which vaccines are recommended for different groups of ... (Department of Health and Human Services) Also in Spanish * Who Should Not Get Vaccinated with These Vaccines? ( ...
Read full-text medical journal articles from Medscapes Offit on Vaccines. ... Give the MenB Vaccine For this low-burden, high-impact, disease, Dr Paul Offit says, Give the MenB vaccine.. Medscape ... New Adjuvanted Flu Vaccine: No Concerns About Narcolepsy A new influenza vaccine adjuvanted with squalene may prompt questions ... Should You Still Administer the HPV-4 Vaccine? Dr Paul Offit provides advice on using up existing stock of HPV-4 vaccine now ...
1982/83 field trials on solar powered refrigerators for vaccine storage  WHO Expanded Programme on Immunization (‎World Health ... Session . Meeting; WHO Global Programme for Vaccines and Immunization (‎World Health OrganizationWorld Health Organization, ... 26th Meeting of the Technical Advisory Group (‎TAG)‎ on Immunization and Vaccine-preventable Diseases in the Western Pacific ... 27th Meeting of the Technical Advisory Group (‎TAG)‎ on Immunization and Vaccine-preventable Diseases in the Western Pacific ...
First workshop of the partners group on Ebola vaccines deployment, 24-26 February 2015, Geneva, Switzerland: summary report  ... Fast-tracking the development and prospective roll-out of vaccines, therapies and diagnostics in response to Ebola virus ... Second WHO High-level meeting on Ebola vaccines access and financing, 8 January 2015: summary report  ... First workshop of the partners group on Ebola vaccines deployment, 24-26 February 2015, Geneva, Switzerland: summary report: ...
Vaccines, Live, Viral. Class Summary. Vaccinia vaccine promotes active immunity against the smallpox virus by inducing specific ... Another vaccine (smallpox [vaccinia] and monkeypox vaccine, live, nonreplicating [Jynneos]) has also been approved by the FDA ... Defending against smallpox: a focus on vaccines. Expert Rev Vaccines. 2016 Sep. 15 (9):1197-211. [QxMD MEDLINE Link]. [Full ... Vaccine is derived from a vaccinia virus, a virus that is closely related to, but less harmful than, variola or monkeypox ...
Enhanced inactivated JE vaccine produced in primary hamster kidney cells. Live-Attenuated Vaccine. Vaccine stability and ... Inactivated Primary Hamster Kidney Cell-Derived JE Vaccine. Live Attenuated JE Vaccine. Vaccine Indications. Endemic Areas. ... Flavivirus vaccines. Vaccine. 6:471-480, 1988. * Oya A. Japanese encephalitis vaccine In: Fukumi H ed. Vaccination Theory and ... Efficacy of Inactivated JE Vaccine. Efficacy Of Inactivated JE Vaccine Produced In Hamster Kidney Cells. Inactivated JE Vaccine ...
Vaccine Safety Monitoring. After any vaccine is authorized for use, including COVID vaccines, multiple safety monitoring ... Compare vaccine types: Snapshot of the COVID-19 Vaccines (WA Dept. of Health, PDF). View this document in other languages:. ... If a vaccine meets the FDAs safety and effectiveness standards, the FDA can make the vaccines available for use in the U.S. by ... COVID-19 vaccine is free and no insurance required. Everyone age 6 months and older can get a COVID-19 vaccine. CDC recommends ...
The city loosened the residency requirement and expanded those eligible to receive the monkeypox vaccine in a bid to get more ... Department of Health program can receive the vaccine as long as they meet one of the other criteria. The vaccine was previously ... The District has more cases - 321 as of Friday - than any state, but has seen a decline in demand for the vaccine, which Ashley ... Instead of specifying the behavior that qualifies individuals for vaccine, they will only have to attest that they meet one of ...
How the Covid-19 Vaccines Work. *Symptoms of Covid-19. *What Happens in an Infection ...
Enable Javascript support in the browser ...
Learn how the Novavax COVID-19 vaccine works, how safe and effective it is, and who can get it when. ... COVID-19 Vaccines: Stay up to date on which vaccines are available, who can get them, and how safe they are. ... Early vaccine trial results published by Novavax revealed a strong antibody response to the vaccine in animals. By August 2020 ... NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge.Vaccine. 2020;38(50):7892- ...
Vaxxers: The Inside Story of the Oxford AstraZeneca Vaccine and the Race Against the Virus Sarah Gilbert & Catherine Green ... The COVID vaccine makers tell all. A book from the Oxford-AstraZeneca team, and a documentary, go behind the scenes in the race ... The Vaccine Directors: Catherine Gale & Caleb Hellerman Wingspan (2021). Last August, biologist Catherine Green was camping ... The book, along with The Vaccine - a documentary commissioned by the BBC and CNN Films - offers a welcome glimpse inside the ...
... the water we drink and the medicines and vaccines that treat and protect us. The Organization aims to provide every child, ... A vaccine is a biological preparation that improves immunity to a particular disease. ... Investment case for vaccine-preventable diseases surveillance in the African Region 2020-2030. The investment case for vaccine- ... A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent ...
All of David Ickes premium content, as well as a wide range of films and series are now available on Ickonic - subscribe today to receive full access. Join Here ...
  • The recommended childhood and adolescent immunization schedule is available at . (
  • The immunization schedules for infants and children in the United States do not provide specific guidelines for those traveling internationally before the age when specific vaccines are routinely recommended. (
  • The Centers for Disease Control and Prevention (CDC) are likely to add the COVID-19 vaccine to the immunization schedule for children and adolescents. (
  • This means that adding the COVID-19 vaccine to the childhood immunization schedule will create a tremendous incentive for blue states to require it for public school children. (
  • Parents who are disinclined to give their children the COVID-19 vaccine might start to wonder whether the other vaccines on the childhood immunization schedule are similarly unnecessary-which could have dire results for public health. (
  • The J&J vaccine is only one dose, compared to the vaccines developed by Moderna and Pfizer - which require two doses for full immunization. (
  • On Sunday, the U.S. Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) also voted to recommend J&J's vaccine for emergency use for individuals ages 18 and older. (
  • A vaccine, or immunization, schedule lists which vaccines are recommended for different groups of people. (
  • WHO Global Programme for Vaccines and Immunization. (
  • The continued public health impact of JE in the region has led to efforts in Thailand and more recently in Vietnam to implement programs of childhood immunization and vaccine production. (
  • For additional information about vaccine storage during a power outage, see the guidance provided by the CDC National Immunization Program at or contac t your state or local health department. (
  • Research and development of new vaccines has the potential to contribute to better immunization programmes and to reduce further childhood mortality in line with the Health related Millennium Development Goals (MDGs). (
  • It covers some of the historical and theoretical background on immunization and offers details on the use of twelve common vaccines administered in the U.S.A. The instructional method is evocative, relying on the learner to make logical (or sometimes intuitive) choices based on their background in basic immunology and human development. (
  • The FDA announced late Thursday that it would issue an emergency use authorization (EUA) for Moderna's COVID vaccine, bringing our immunization arsenal to a total of two. (
  • The US childhood immunization schedule specifies 26 vaccine doses for infants aged less than 1 year--the most in the world--yet 33 nations have lower IMRs. (
  • Since 1997, the Advisory Committee on Immunization Practices (ACIP) has recommended the routine vaccination of pregnant women with trivalent inactivated influenza vaccine (TIV) after the first trimester of pregnancy. (
  • In fact, when it comes to immunization, "plant-based" simply means researchers recruited plants to produce part of the vaccine, Brian Ward, MD , Medical Officer at Medicago, said. (
  • As of Jan. 21, more than 15,000 pregnant patients had received an mRNA vaccine," said retired Navy Capt. (Dr.) Margaret Ryan, medical director, Defense Health Agency Immunization Division, Pacific Region Vaccine Safety Hub, San Diego. (
  • The U.S. Food and Drug Administration (FDA) has licensed ACAM2000® , (Smallpox [Vaccinia] Vaccine, Live), a replication-competent vaccine, for active immunization against smallpox disease in persons determined to be at high risk for smallpox infection. (
  • In October 2014, the FDA approved the first vaccine for active immunization to prevent invasive meningococcal disease caused by N meningitidis serogroup B in individuals aged 10 through 25 years. (
  • The human papillomavirus (HPV) vaccine is used on a large scale in immunization programs in more than 58 countries, with resultant efficacy and safety for precursor lesions of cervical cancer, in addition to anogenital lesions. (
  • The benefits of receiving a COVID-19 vaccine outweigh any potential risks of vaccination during pregnancy. (
  • Vaccines and high rates of vaccination have made these diseases much less common in the United States. (
  • The World Health Organization issued temporary vaccination recommendations for residents of and long-term visitors to countries with active circulation of wild or vaccine-derived poliovirus. (
  • Interactive tools for determining routine and catch-up childhood vaccination are available at . (
  • V-safe users or others who get vaccinated can report any possible health problems or adverse events following vaccination to the Vaccine Adverse Event Reporting System (VAERS) . (
  • CDC is developing a new version of v-safe , launching later this year, which will allow users to share their post-vaccination experiences with new vaccines. (
  • Completing health check-ins and sharing how you feel, even if you don't experience side effects after vaccination, helps CDC's vaccine safety monitoring efforts. (
  • Among adults aged 75 years and older, effectiveness of full vaccination is estimated at 91% for Pfizer-BioNTech, 96% for Moderna, and 85% for Janssen vaccine products. (
  • But it can also mean the same thing as vaccination, which is getting a vaccine to become protected against a disease. (
  • Children with autism, and their younger siblings, have lower vaccination rates than other children, placing them at risk for vaccine-preventable disease. (
  • Learn more about vaccination for youth at . (
  • Enter your zip code in Washington's Vaccine Locator tool or check our Getting Vaccinated page to find a vaccination site near you. (
  • While this is the first time we've seen international-scale vaccination programs, adenovirus vaccines are not new. (
  • Significant clustering within the first week after vaccination, especially after dose 2, provides additional evidence of an association between mRNA vaccines and myocarditis/pericarditis in younger individuals," the researchers wrote, referring to earlier studies that have shown a small increased risk. (
  • In this interim analysis of surveillance data from 6.2 million people who received 11.8 million doses of an mRNA vaccine, event rates for 23 serious health outcomes weren't significantly higher for individuals one to 21 days after vaccination compared with similar individuals at 22 to 42 days after vaccination," the researchers wrote. (
  • Zients said that as of Friday, 100 million Americans had either received their second vaccination shot of either Pfizer or Moderna's vaccines or a single shot of the Johnson & Johnson vaccine. (
  • A new documentary, "Vaccination From The Misinformation Virus," looks to address the effectiveness of vaccines and why some are hesitant to take them. (
  • We had worked on a project on childhood obesity and an infectious disease doctor at University of Mexico Hospital, Dr. Walter Dehority, took me to lunch and said, 'You know, our vaccination rates are down all over the country childhood vaccinations, in particular, flu vaccines, shingles vaccines. (
  • Today, the rest of the study covering neurological symptoms following vaccination and a history of vaccines demonstrating little benefit is reviewed. (
  • The deaths of 19 infants of SIDS (sudden infant death syndrome) shortly after vaccination with two hexavalent vaccines were described in a paper. (
  • Those authors suggested that, though it hadn't been proven that vaccines had caused their deaths, "it is a signal that brings to attention the need to monitor the course of vaccination and its complications. (
  • Converted spaces, like empty stadiums, airplane hangars and deserted malls have served as vaccination hubs during the United States vaccine rollout. (
  • People wait in line to receive the COVID-19 vaccine at a mass vaccination site in a parking lot for Disneyland Resort on Jan. 13, 2021, in Anaheim, Calif. (
  • Louis Pasteur generalized Jenner's idea by developing what he called a rabies vaccine (now termed an antitoxin), and in the 19th century compulsory vaccination laws were passed. (
  • These children can still safely receive the vaccine in community vaccination clinics, GP clinics or from other immunisation providers. (
  • Washington residents get their coronavirus vaccines through Swedish's mobile vaccination clinic set up in Federal Way. (
  • Chen stressed that the government will make sure the vaccine is safe to use before allowing Taiwanese people to be vaccinated after reports of blood clots forming among some people who had received the inoculation, leading 13 European countries to pause their vaccination programs. (
  • Evidence that vaccination increases the risk of invasive cancer can be rapid, if the vaccine changes the natural history of cancer by accelerating it. (
  • In Germany, health minister Karl Lauterbach said that inoculations with the new vaccines could start next week and that "now is the optimal time to close vaccination gaps for the fall. (
  • As a replication-deficient vaccine, it can be used for vaccination of people 18 years and older with certain immune deficiencies or conditions, such as HIV or atopic dermatitis. (
  • The CDC updated COVID-19 vaccine recommendations for vaccination in April 2023 to simplify and allow flexibility for people at higher risk. (
  • Initial data with showed effectiveness of full vaccination with monoclonal vaccines in older adults to prevent hospitalization was estimated for the period between February through April 2021. (
  • After the introduction of quadrivalent HPV vaccine (6,11,16 and 18) in Brazil in 2014, monitoring the vaccination coverage and the development of HPV prevalence incidence of cervical abnormalities and precancerous lesions must be observed, as well as morbidity and mortality trends from in situ and invasive cancer. (
  • The White House announced that vaccines will be required for international travelers coming into the United States, with an effective date of November 8, 2021. (
  • A worker speaks with people waiting to get their coronavirus vaccine shot at the Washington Heights Armory, Jan. 26, 2021. (
  • Novavax announced on June 14, 2021, that the vaccine was 90.4% effective in a preliminary analysis of data from its Phase 3 trial in the U.S. and Mexico. (
  • Pharmaceutical company AstraZeneca of Cambridge, UK, aims to produce three billion doses of this vaccine for distribution around the world by the end of 2021, significantly protecting people from severe disease and death. (
  • A member of staff at the university hospital prepares the Moderna vaccine against COVID-19 in Duesseldorf, Monday, Jan. 18, 2021. (
  • Nurse Lisa Wheeler administers a dose of the Pfizer-BioNTech COVID-19 vaccine to Cristina Montins, 40, at Ellis Davis Fieldhouse, a Parkland Hospital testing and vaccine location, in Dallas on Wednesday, March 3, 2021. (
  • Researchers from Kaiser Permanente Vaccine Study Center led the study, which consisted of analyzing vaccine surveillance data from the Vaccine Safety Datalink (VSD) on 6.2 million vaccinated members of eight US health plans from Dec 14, 2020, to Jun 26, 2021. (
  • A food court is set up as an observation area, where people who have received the vaccine can be monitored before leaving, at Fenway Park in Boston, Mass. on Jan. 29, 2021. (
  • Stephanie Birman, right, a Seattle Sounders season ticket holder, gets the Johnson & Johnson COVID-19 vaccine at a clinic in a concourse at Lumen Field, May 2, 2021, prior to an MLS soccer match between the Sounders and the Los Angeles Galaxy. (
  • Rene Urey an LAUSD special education assistant gets his COVID-19 vaccine aboard a school bus that transported him to the SoFi Stadium in Inglewood, Calif. on March 1, 2021. (
  • LONDON - Some of the world's wealthiest countries are promising to share coronavirus vaccines with the poorest, but details of when and how many remain scarce as leaders of the Group of Seven economic powers hold their first meeting of 2021 on Friday. (
  • Navy Hospitalman Gabriel Cabral, assigned to Naval Medical Center San Diego, from Maryland, administers first-round of Pfizer-BioNTech COVID-19 vaccine sailors and select Department of Defense support staff onboard Naval Air Facility EL Centro, California on March 4, 2021 (Photo by: Navy Petty Officer 3rd Class Drew Verbis, Navy Operational Support Center - Phoenix). (
  • Sailors and select Department of Defense support staff began receiving the first-round of Pfizer-BioNTech COVID-19 vaccine onboard Naval Air Facility EL Centro in California, March 4, 2021. (
  • FRIDAY, Jan. 15, 2021 (HealthDay News) -- Now that federal guidelines have expanded COVID-19 vaccine eligibility to include people over 65 and those of all ages with underlying health conditions, drug stores say they are ready, willing and able to start giving the shots. (
  • Effectiveness of COVID-19 mRNA Vaccines in Preventing COVID-19-Associated Outpatient Visits and Hospitalizations Among American Indian and Alaska Native Persons, January-November 2021: A Test-Negative Case-Control Analysis Using Surveillance Data. (
  • Vaccine effectiveness against transmission of alpha, delta and omicron SARS-COV-2-infection, Belgian contact tracing, 2021-2022. (
  • Everyone aged 5 (on or before 31 August 2022) and over can get a 1st and 2nd dose of the COVID-19 vaccine. (
  • [ 1 ] As of August 31, 2022, The New York Times Coronavirus Vaccine Tracker lists 2 mRNA vaccines (Comirnaty by Pfizer and Spikevax by Moderna) that have gained full approval by the US Food and Drug Administration (FDA). (
  • Because of this, new bivalent mRNA vaccine boosters were authorized in Fall 2022 containing omicron BA.4/BA.5 components. (
  • On August 19, 2022, the Food and Drug Administration (FDA) authorized the Novavax COVID-19 Vaccine, Adjuvanted for emergency use in individuals ages 12 and older. (
  • BP profits hit record £23BILLION in 2022 while en. (
  • The NVI and World Health Organization (WHO) co-organized the "10th National Vaccine Conference" during March 16-18, 2022, under the theme "Vaccines: Tools for Sustainable Prevention and Control of Emerging Infectious Diseases" in an online format to update on academic progress, communicate the direction of national vaccine development, and encourage knowledge and experience exchange. (
  • This two-dose COVID-19 vaccine is the first plant-based vaccine authorized for use in humans, according to this study from June 2022 in The New England Journal of Medicine . (
  • Medicago's vaccine method is different-it starts by introducing the genetic code for making the spike protein into plants, not humans, according to the June 2022 study in The New England Journal of Medicine . (
  • Globally, at least 12 vaccines are approved for full use, more than 20 vaccines are authorized for early or limited use, and as of Fall 2022, 42 vaccines were in phase 3 clinical trials. (
  • Taking into account diminished VE, new bivalent mRNA vaccine boosters were authorized in Fall 2022 containing Omicron BA.4/BA.5 components. (
  • V-safe was developed specifically for COVID-19 vaccines and has been an essential component of the pandemic vaccine safety monitoring systems that have successfully and comprehensively characterized the safety of the COVID-19 vaccines used in the United States. (
  • CDC Director Dr. Rochelle Walensky called the decision 'another milestone toward an end to the pandemic' and said the vaccine is 'another important tool in our toolbox to equitably vaccinate as many people as possible, as quickly as possible. (
  • The book, along with The Vaccine - a documentary commissioned by the BBC and CNN Films - offers a welcome glimpse inside the race to develop COVID-19 vaccines in the middle of a raging pandemic. (
  • We are not working with or through third parties for vaccine access during the current emergency pandemic period,' it said in a statement to Reuters. (
  • This was nothing like anti-vaccine rhetoric, but rather a sound warning drawn from experience: Trump has muzzled, suppressed and sidelined scientific experts at every stage of the pandemic. (
  • Tedros, an Ethiopian who goes by his first name, nonetheless hailed the scientific achievement behind rolling out coronavirus vaccines less than a year after the pandemic erupted in China, where a WHO-backed team has now been deployed to look into origins of the coronavirus. (
  • Attitudes about the COVID pandemic and the vaccines also affect who gets the shots. (
  • For over two years of Covid-19 pandemic, the National Vaccine Institute (NVI) has formulated many approaches and committed to disseminating accurate and reliable information for the general public. (
  • Prof. Emeritus Piyasakol Sakolsatayadorn, M.D., Chairman of Mahidol University Council, gave a special keynote speech on "Vaccine Preparedness and Management in Thailand during the Covid-19 Pandemic," saying: "Covid-19 won't be the last pandemic. (
  • A comparison of fetal-loss reports in the Vaccine Adverse Event Reporting System (VAERS) during three consecutive influenza seasons shows there was a synergistic toxicity causing spontaneous abortions (SAB) and stiillbirths (SB) following the Center for Disease Control (CDC) recommendations of pandemic and influenza vaccines administered to pregnant women. (
  • Goldman's most recent study Comparison of VAERS fetal-loss reports during three consecutive influenza seasons successfully correlated fetal toxicity resulting from the administration of both the pandemic (A-H1N1) and seasonal influenza vaccines during the 2009/10 season. (
  • The safety and effectiveness of the pandemic (monovalent influenza) A-H1N1 vaccine had not been previously established in pregnant women. (
  • Unlike its predecessors, the new vaccine may work for life, and it may be possible to manufacture it quickly enough to stop a pandemic. (
  • Influenza vaccines based on mRNA may offer a solution as sequence-matched, clinical-grade material could be produced reliably and rapidly in a scalable process, allowing quick response to the emergence of pandemic strains. (
  • More related news stories about injuries and deaths caused by Wuhan coronavirus (Covid-19) vaccines can be found at . (
  • The COVID-19 vaccines are unprecedented feats of science, but some of the most powerful tools for defeating the pandemic have been right in front of us all along. (
  • Scientists hope the new boosters will trigger a strong response from the immune system to prevent not just serious illness but perhaps milder infections also-much like the original vaccines did earlier in the pandemic, before super-contagious mutants emerged. (
  • Recommended age limitations are based on potential adverse events (yellow fever vaccine), lack of efficacy data or inadequate immune response (polysaccharide vaccines and influenza vaccine), maternal antibody interference and immaturity of the immune system (measles-mumps-rubella [MMR] vaccine), or lack of safety data. (
  • Since influenza viruses may be circulating at any time of the year, travelers aged ≥6 months who were not vaccinated during the influenza season of their country of residence should be vaccinated ≥2 weeks before departure if vaccine is available. (
  • New Adjuvanted Flu Vaccine: No Concerns About Narcolepsy A new influenza vaccine adjuvanted with squalene may prompt questions about narcolepsy. (
  • The results build on previous success in animal studies with a nasal nanoemulsion vaccine for influenza, reported by University of Michigan researchers in 2003. (
  • In 2011, Dr. Alessandro Bertoucci who analyzed the practices of 256 physicians treating more than 600,000 patients, reported that a staggering 91% of pregnant women are declining influenza vaccines due to fears of miscarriage and suspected toxins in the vaccine itself. (
  • Many of these studies, used "no Thimerosal" influenza vaccines, had insufficient statistical power to adequately detect and assess complications due to the small sample size. (
  • Nor was the combination of two different influenza vaccines ever tested in pregnant women. (
  • An independent survey was conducted by the National Coalition of Organized Women (NCOW) via the Internet to serve as a second surveillance source for pregnant women suffering A-H1N1 fetal loss during the two-vaccine 2009/10 influenza season. (
  • ABSTRACT - Despite substantial improvements, influenza vaccine production-and availability-remain suboptimal. (
  • Here we show that mRNA vaccines induce balanced, long-lived and protective immunity to influenza A virus infections in even very young and very old mice and that the vaccine remains protective upon thermal stress. (
  • In ferrets and pigs, mRNA vaccines induce immunological correlates of protection and protective effects similar to those of a licensed influenza vaccine in pigs. (
  • Thus, mRNA vaccines could address substantial medical need in the area of influenza prophylaxis and the broader realm of anti-infective vaccinology. (
  • If your child has a chronic medical condition, it is strongly recommended that they have an annual influenza vaccine. (
  • How is the influenza vaccine given? (
  • When should I give the influenza vaccine? (
  • Influenza viruses change every year, so a new flu vaccine is developed annually to protect against the most common strains expected to be seen that year. (
  • The flu vaccine cannot cause influenza. (
  • The distribution of the COVID-19 vaccine follows protocols established by prior influenza vaccine seasons. (
  • Sister Elaine Maguire traveled to the Washington Heights Armory from Leonia, N.J., to get her first coronavirus vaccine shot. (
  • The first patient enrolled in Pfizer's COVID-19 coronavirus vaccine clinical trial at the University of Maryland School of Medicine in Baltimore on May 4, 2020. (
  • ABC15 received an inside look at one of the first Valley health clinics approved to distribute a potential coronavirus vaccine. (
  • On May 19, 2023, CDC will close enrollment in v-safe for COVID-19 vaccines. (
  • Rapid Review Quiz: Unusual Vaccine News - Medscape - Feb 13, 2023. (
  • As of March 21, 2023, enrollment in v-safe for mpox vaccine has closed. (
  • Most people aged ≥ 6 years who are not moderately or severely immunocompromised and have received 1 dose of a bivalent mRNA vaccine (from either Moderna or Pfizer ) do not need any further vaccine doses as of April 2023. (
  • The J&J vaccine also is easier to handle, lasting three months in the refrigerator compared to the Pfizer and Moderna options, which must be frozen. (
  • Meanwhile, state officials have a lot to do to make sure they can distribute the vaccines to all corners of the state, keep track of who gets what, and convince New Yorkers of all ages that the Pfizer and Moderna vaccines, each of which requires two doses weeks apart, are safe and effective. (
  • How does Johnson & Johnson's COVID-19 vaccine stack up against shots from Pfizer and Moderna? (
  • At first glance, the vaccine doesn't appear to be as stellar as FDA authorized vaccines from Pfizer and Moderna, but it does have a few perks. (
  • The technology behind the Pfizer and Moderna vaccines is mRNA. (
  • The COVID-19 vaccines made by Pfizer and Moderna are mRNA vaccines. (
  • Data on the safety of receiving an mRNA COVID-19 vaccine (Moderna or Pfizer-BioNTech), before and during pregnancy are reassuring. (
  • Most people will be offered a booster dose of the Pfizer/BioNTech vaccine or Moderna vaccine. (
  • The committee will meet in open session to discuss the Pfizer-BioNTech supplemental Biologics License Application for COMIRNATY for administration of a third dose, or "booster" dose, of the COVID-19 vaccine, in individuals 16 years of age and older. (
  • TAIPEI, June 1 (Reuters) - Foxconn (2317.TW) and its billionaire founder Terry Gou sought permission from Taiwan's government on Tuesday to buy COVID-19 vaccines from Germany's BioNTech SE (22UAy.DE) after the island was hit with a rise in infections. (
  • Shanghai Fosun Pharmaceutical Group Co Ltd (600196.SS) has a contract with BioNTech to sell the vaccines in Greater China, including to Taiwan, but Taiwan's government says it has and will only deal with BioNTech in Germany and that it does not trust vaccines from China. (
  • China's Taiwan Affairs Office, in a statement to Reuters, reiterated that it was Fosun's commercial right to sell the BioNTech vaccine to Taiwan and that China's government was coordinating with 'relevant parties' on the island to talk to Fosun. (
  • Of 6.2 million participants, 57% received the Pfizer/BioNTech COVID-19 vaccine, and the remainder received Moderna. (
  • The Moderna vaccine joins the Pfizer / BioNTech shot as the second licensed vaccine against the coronavirus in the United States. (
  • Pfizer and BioNTech have won permission for emergency use of their COVID-19 vaccine in Britain. (
  • Through a partnership with Walgreens, Hermitage was able to administer the Pfizer BioNTech vaccine to 86 assisted living residents, 17 health care center residents and 89 staff members - or around 95% of residents and 85% of staff. (
  • This vaccine is similar to the Pfizer/BioNTech one that got an EUA last week. (
  • Left: Pfizer/BioNTech vaccine, right: Moderna vaccine. (
  • The Pfizer/BioNTech vaccine needs to stay ultra-cold, so it's being distributed in thermos-like packages that each contain 975 doses. (
  • Others, like the Pfizer-BioNTech and Moderna vaccines, carry a genetic code for the spike protein, which our bodies then make and destroy, kind of like a practice run, according to the CDC. (
  • Vials of the Pfizer-BioNTech Covid-19 vaccine. (
  • Moderna and Pfizer/BioNTech have advanced their vaccines to the final round of testing, which involves about 30,000 patients each. (
  • The European Medicines Agency has recommended the authorization of two coronavirus vaccines made by Pfizer-BioNTech and Moderna Inc., tweaked to include protection against an early version of the omicron variant. (
  • The regulator is also currently reviewing an updated version of the Pfizer-BioNTech vaccine that aims to protect against the later BA.4 and BA.5 omicron variants. (
  • It provides the number of bivalent mRNA vaccine doses an individual needs based on COVID-19 vaccine doses previously received, including the number of prior doses, whether the doses were monovalent or bivalent, and the vaccine manufacturer (Moderna, Novavax, or Pfizer-BioNTech). (
  • Cancer vaccines have indeed been developed, and the strategies employed are varied and mimic the approaches used for developing vaccines against infectious pathogens. (
  • The perspective notes that once a vaccine platform is established, such as that for DNA or mRNA vaccines, potentially it can be applied to multiple pathogens, especially within virus classes or families. (
  • [ 18 ] Similarly, scientists are working to develop vaccines to treat rabies and other veterinary-related pathogens. (
  • The Pentagon's efforts at speedier responses to infectious diseases is getting turbocharged, as researchers at Arizona State University kick off a program to develop vaccines that can inoculate against unknown pathogens - and do it within a week. (
  • The British government said Johnson will ask U.K. Chief Scientific Adviser Patrick Vallance to work with the World Health Organization and others on "speeding up the process for developing vaccines, treatments and tests for common pathogens. (
  • This article focuses on antigen-encoding RNA-based vaccines that are either directed against tumors or pathogens. (
  • And in mid-July, the U.S. sent half a million doses of the Moderna vaccine through COVAX to the Caribbean nation. (
  • In total, Taiwan has signed contracts to purchase a total of 10 million doses of the AstraZeneca vaccine, 5.05 million doses of the Moderna vaccine and 4.76 million doses of vaccines through the COVAX allocation program. (
  • Vaccine hesitancy is often cited as the main reason. (
  • Although not addressed in the new AAP statement, the issue of vaccine hesitancy is relevant. (
  • Nonetheless, vaccine hesitancy is on the rise. (
  • Two leading vaccines Moderna and Pfizer are required to be stored at subzero temperatures. (
  • Gardasil, the trade name of a human papillomavirus (HPV) vaccine, protects against. (
  • Dr. Donald Brown inoculates 14-year-old Kelly Kent with Gardiasil, a new vaccine for the human papillomavirus (HPV),which can cause cervical cancer. (
  • Historically, the notion of immunizing humans against infections actually preceded the development of the germ theory and the discovery of the first scientific vaccine (against smallpox) in the year 1796 by Edward Jenner. (
  • 300 million died of smallpox, they found a vaccine, and we have wiped out smallpox. (
  • We used whole virus in the smallpox vaccine. (
  • The smallpox results, which appear in the February issue of Clinical Vaccine Immunology, could lead to an effective human vaccine against smallpox that is safer than the present live-vaccinia virus vaccine because it would use nanoemulsion-killed vaccinia virus, says Baker. (
  • If the federal government conducts further studies and finds the nanoemulsion smallpox vaccine effective in people, it could be a safer way to protect citizens and health care workers in the event of a bioterrorism attack involving smallpox, Baker says. (
  • On the eve of the Iraq War, the Bush administration proposed a voluntary program to vaccinate military personnel and 500,000 health care workers with the existing vaccine to prepare for the possible use of smallpox virus as a biological weapon. (
  • The first vaccine developed was against smallpox by Edward Jenner, English "country" physician, in Berkeley. (
  • The Centers for Disease Control and Prevention's (CDC) Drug Services provides smallpox vaccine to these recommended individuals as needed. (
  • ACAM2000® and JYNNEOS TM (also known as Imvamune or Imvanex) are the only two licensed smallpox vaccines in the United States. (
  • Aventis Pasteur Smallpox Vaccine (APSV) is an investigational vaccine that may be used in a smallpox emergency under the appropriate regulatory mechanism (i.e. (
  • The vaccine does not contain variola virus and cannot cause smallpox. (
  • Replication-competent smallpox vaccine consists of a live, infectious vaccinia virus that can be transmitted from the vaccine recipient to unvaccinated persons who have close contact with the inoculation site, or with exudate from the site. (
  • The FDA has licensed JYNNEOS TM (also known by the brand names Imvamune and Imvanex), a replication-deficient smallpox vaccine, for the prevention of smallpox and monkeypox. (
  • Ask an Infectious Disease Expert: Will COVID-19 Vaccines Work Against New Variants? (
  • Vaccines have proven to be the most cost effective public health tool in the fight against infectious diseases. (
  • Improvements in scientific knowledge and development of new technologies have accelerated vaccine development and resulted in the testing of new vaccines against common infectious diseases. (
  • Novel vaccine technologies are critical to improving the public health response to infectious disease threats that continually emerge and re-emerge, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (
  • The perspective concludes that modern vaccine technology and improved surveillance in developing countries ultimately can help us better prepare for emerging infectious disease threats. (
  • DNA vaccines designed to target infectious hematopoietic necrosis virus (IHNV) are effective at protecting salmon and rainbow trout from this often fatal blight. (
  • Melanie Saville, M.D., Executive Director of Vaccine Research and Development, Coalition for Epidemic Preparedness Innovations (CEPI), shared about CEPI's efforts to grow its vaccine research and development portfolio: "Our goal is to accelerate the development of vaccines against emerging infectious diseases and enable equitable access to these vaccines for people during outbreaks. (
  • New Scientist - In a first for any infectious disease, a vaccine against flu has been made out of messenger RNA (mRNA) - the genetic material that controls the production of proteins. (
  • Amazingly, mRNA vaccines have never been really tested against infectious diseases," says Stitz. (
  • The National Institutes of Health (NIH) and the Office of Infectious Disease and HIV/AIDS Policy (OIDP) also support ongoing research on vaccines and vaccine safety. (
  • Interestingly, depending on whether RNA-based vaccines are directed against tumors or infectious disease, they are formally considered gene therapy products or not, respectively. (
  • Many who are pregnant are health care providers who said the risk of getting COVID-19 from their patients was worse than that from getting the vaccine," said Fauci, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. (
  • Globally, 12 vaccines are approved for full use, 21 vaccines are authorized for early or limited use, and 42 vaccines are in phase 3 clinical trials. (
  • By summer 2020, early clinical trials showed that the vaccine appeared to be safe, and more advanced trials entered the planning stage in the United States and other countries. (
  • The company also announced that the vaccine was 60% effective in a Phase 2b clinical trial in South Africa and included protection from the South African variant B.1.351, also called the Beta variant. (
  • She runs a clinical biomanufacturing facility at the University of Oxford, UK, and is part of a team that had developed a COVID-19 vaccine that was in clinical trials at the time. (
  • Although I have reported on many aspects of COVID-19 vaccine development over the past year, I was surprised to learn the extent to which they had to gamble in those early days, without knowing if funding would come through - and that the vials of vaccine used in the first clinical trials were filled by hand at Oxford's facility. (
  • More clinical trials are increasingly being planned for Africa to evaluate efficacy and safety of candidate vaccines. (
  • Building capacity for scientifically valid and ethically acceptable clinical trials of vaccines in Africa. (
  • Providing guidelines and standards for vaccine clinical trials in Africa. (
  • Sustaining and/or building partnerships for vaccine research and development in order to conduct vaccine clinical trials and accelerate the introduction of new vaccines in Africa. (
  • It's now well over a year since tens of thousands of recipients received their vaccine in the first round of clinical trials, and over six months since the global rollout started. (
  • The full approval is based on clinical trial data from nearly 30,000 people, which showed the vaccine was safe and effective protection against COVID-19. (
  • [ 20 , 21 ] While it is unlikely that any one single strategy will suddenly cure cancer, the small victories which have already been achieved with DNA vaccines have made advocates of gene therapy eager to press forward in developing this powerful clinical tool. (
  • During a clinical trial, a vaccine is tested on people who volunteer to get vaccinated. (
  • CISA does clinical vaccine safety research and-at the request of providers-evaluates complex cases of possible vaccine side effects in specific patients. (
  • Besides an overview on the current clinical use of mRNA vaccines in various therapeutic areas a detailed discussion of the current regulatory situation is provided and regulatory perspectives are discussed. (
  • It takes time to enlist the tens of thousands of people needed to do a proper clinical trial, said Paul Offit, director of the Vaccine Education Center at the Children's Hospital of Philadelphia. (
  • Pregnant people are entering clinical trials for COVID-19 vaccines "literally now and going into March, so more data will be known soon," Dr. Anthony Fauci, President Joe Biden's chief medical adviser on COVID-19, told a Blue Star Families virtual town hall Feb. 4. (
  • Two others, a viral vector vaccine (Janssen) and an adjuvanted protein subunit vaccine (Novavax), have emergency use approval (EUA) in the United States. (
  • Viral vector vaccines use genetic material, which gives your cells instructions for making a protein of the germ. (
  • Historically, vaccines against viral diseases have used live-attenuated (weakened) viruses or inactivated whole viruses to induce protective immune responses. (
  • Novel vaccine technologies: essential components of an adequate response to emerging viral diseases. (
  • The researchers point out that DNA is not only cheap to produce, it also doesn't require refrigeration, unlike other viral vaccines. (
  • This vaccine format elicits B and T cell-dependent protection and targets multiple antigens, including the highly conserved viral nucleoprotein, indicating its usefulness as a cross-protective vaccine. (
  • Viral vaccines are used globally to protect humans against infections. (
  • Several veterinary vaccines using this technique are on the market, including immunizations against West Nile virus in horses, melanoma in dogs and a viral disease in salmon. (
  • The company began a Phase 3 trial of its vaccine candidate, NVX‑CoV2373, in the United Kingdom in September 2020. (
  • Novavax has for years worked on developing its recombinant nanoparticle technology, and created the first COVID-19 vaccine using this method in the spring of 2020. (
  • Soon after news of SARS-CoV-2 arrives in early January 2020, Gilbert and Green decide that COVID-19 could be Disease X. They risk their reputations and a substantial amount of Oxford's money to prepare a vaccine, even before the need becomes clear. (
  • As they do with all vaccines and drugs, AstraZeneca and Pfizer completed trials in populations around the world throughout 2020. (
  • We calculate that the number of travellers to TD risk regions was 88 million in 2003 and may reach 190 million per annum by 2020, suggesting that a significant potential market exists for a TD vaccine. (
  • FILE - A nurse prepares a shot as the world's biggest study of a possible COVID-19 vaccine, developed by the National Institutes of Health and Moderna Inc., gets under way in Binghamton, N.Y., July 27, 2020. (
  • FILE - Wade Bardo of Erin, N.Y., gets an injection as a study of a possible COVID-19 vaccine gets under way in Binghamton, N.Y., July 27, 2020. (
  • FILE - A poster advertises a hunt for volunteers for a study of a possible COVID-19 vaccine, in Binghamton, N.Y., July 27, 2020. (
  • 2. What information do people need to know about a COVID vaccine? (
  • 3. What would make it more likely that you would get a COVID vaccine? (
  • 4. What agencies do you trust to give accurate information about a COVID vaccine? (
  • 5. Who do you trust in your community to give advice or guidance about a COVID vaccine? (
  • What Will It Feel Like to Get a COVID Vaccine? (
  • Nearly 4 million doses of the newly approved Johnson & Johnson vaccine were shipped Sunday night and will begin to be delivered to states for injections starting Tuesday, officials said. (
  • Taiwan's Buddha Light International Association has also proposed importing up to 500,000 shots of Johnson & Johnson's (JNJ.N) vaccine. (
  • However, Johnson & Johnson said it was only negotiating with government bodies and supranational organisations like the European Commission for vaccine purchases. (
  • The Johnson & Johnson and Sputnik vaccines are similar. (
  • For example, some-like the Johnson & Johnson vaccine-use a modified virus to introduce the spike protein to our cells, according to the CDC. (
  • Johnson & Johnson's COVID-19 vaccine was shown to be 66% effective at preventing mild and moderate infections, and 85% effective at preventing severe disease, in FDA data released Wednesday. (
  • Johnson vaccines and the first dose of the Moderna series will be offered. (
  • Johnson, whose country has had almost 120,000 coronavirus deaths, will hail the speed with which vaccines have been developed against COVID-19 in less than a year, and announce a push to cut the time needed to create new ones to 100 days. (
  • The development of viable coronavirus vaccines offers the tantalizing prospect of a return to normality, but we must not rest on our laurels," Johnson said in comments released by his 10 Downing St. office. (
  • Johnson will promise Friday to give "the majority of any future surplus vaccines" to the U.N.-backed COVAX effort to vaccinate the world's most vulnerable people, the British government said ahead of the summit. (
  • This COCA Call will present the latest evidence on thrombosis with thrombocytopenia syndrome (TTS) after administration of the Johnson & Johnson/Janssen COVID-19 vaccine. (
  • Pfizer bivalent booster shots are also available for persons 18 years and older who received a single dose of the Johnson & Johnson/Janssen vaccine and at least two months have passed. (
  • Moderna bivalent booster shots are also available for persons 18 years and older who received a single dose of the Johnson & Johnson/Janssen vaccine and at least two months have passed. (
  • Dr. Poland is the chair of a Safety Evaluation Committee for non-rubella vaccine trials being conducted by Merck Research Laboratories. (
  • The record time was achieved because the technologies for making the vaccines were quick to deploy, the three phases of trials were done concurrently and the bureaucratic roadblocks were removed - as you would hope for a potentially life-saving vaccine required at a global scale. (
  • Modern engineered vaccines - where a conspicuous bit of the target pathogen is placed like a passenger into the adenovirus chassis - have been used on thousands of individuals in trials to prevent Ebola, malaria, dengue, Marburg and HIV infections. (
  • Phase 3 trials for three candidate vaccines are underway in the U.S., involving recruitment of about 30,000 subjects each. (
  • Safety surveillance is important, the researchers noted, because rare or severe outcomes may go unnoticed in phase 3 trials because of limited sample size, restrictive inclusion criteria, short follow-up, and trial participants who may be different from people who will ultimately receive the vaccine. (
  • Merck and Co. pharmaceutical company has a new personalized cancer vaccine from Moderna in human trials. (
  • The latter making headlines Monday after researchers announced Pfizer's vaccine is so far more than 90 percent effective in phase three trials. (
  • Cumulative COVID incidence in the vaccine and control groups of the two trials. (
  • Both vaccines turned out to be around 95% effective in trials. (
  • Currently, Thailand has many vaccines in the development process with animal and human trials. (
  • Trials found the vaccine, which is produced with the help of plants, to be 70% effective at preventing coronavirus-related illness. (
  • It has an mRNA vaccine against prostate and lung cancer tumours in human trials. (
  • In the meantime, the best available vaccine candidates (either live, whole cell killed or subunit) should be moved forward to non-human primate models and Phase I trials. (
  • This means that safety trials would need extensive follow up before concluding that a live attenuated vaccine was safe. (
  • Search , text your ZIP code to 438829, or call 1-800-232-0233. (
  • This meant huge amounts of data were quickly available to measure the effectiveness of the vaccines in the general population and search for rare side effects. (
  • In a systematic review of the scientific literature on childhood immunizations that will be published in the August issue of Pediatrics, researchers found that vaccine-related adverse events are "extremely rare" and that - once again - the measles/mumps/rubella vaccine (MMR) is not associated with autism. (
  • Wakefield's paper in Lancet in 1998 linking autistic regression and diarrhea following measles-mumps-rubella (MMR) shot fueled a nascent autism-vaccine movement. (
  • People who are pregnant should stay up to date with their COVID-19 vaccines, including getting a COVID-19 booster shot when it's time to get one. (
  • CDC recommends COVID-19 vaccines for everyone aged 6 months and older, including people who are pregnant, breastfeeding, trying to get pregnant now, or those who might become pregnant in the future. (
  • COVID-19 vaccines do not cause COVID-19, including in people who are pregnant or their babies. (
  • Data from vaccine safety monitoring systems have not found any safety concerns for people who received an mRNA COVID-19 vaccine late in pregnancy or for their babies. (
  • Scientists have not found an increased risk for miscarriage among pregnant people who received an mRNA COVID-19 vaccine just before or during early pregnancy (before 20 weeks of pregnancy). (
  • People who are moderately or severely ill should usually wait until they recover before getting MMR vaccine. (
  • In people with serious immune system problems, this vaccine may cause an infection that may be life-threatening. (
  • People with serious immune system problems should not get MMR vaccine. (
  • Several factors influence recommendations for the age at which a vaccine is administered, including age-specific risks of the disease and its complications, the ability of people of a given age to develop an adequate immune response to the vaccine, and potential interference with the immune response by passively transferred maternal antibodies. (
  • The vaccines do a tremendous job of preventing elderly and at-risk people from suffering severe illness and dying, but most children are spared the worst effects of COVID-19, anyway-particularly if they were already infected, which is the case for nearly nine out of every 10 kids , according to the CDC. (
  • Denmark, for instance, is no longer recommending COVID-19 vaccines for otherwise healthy young people under the age of 18. (
  • As a one-dose vaccine, people do not have to return for a second dose to be protected,' Walensky said in a statement of J&J's shot. (
  • A sign dissuades people from showing up without a vaccine appointment at the Washington Heights armory. (
  • Most people can have any of the COVID-19 vaccines, but some people are only offered certain vaccines. (
  • Most people also need a booster dose to help improve the protection from the first 2 doses of the vaccine. (
  • Community immunity is especially important for people who can't get certain vaccines. (
  • The vaccine will be covered by Medicare, Medicaid and most private insurance, and the cost of the vaccine will be covered for people who are uninsured. (
  • As of Saturday, all people of any sexual orientation or gender who have had multiple sexual partners in the past two weeks will be eligible for the vaccine, in accordance with the Centers for Disease Control and Prevention. (
  • The District has more cases - 321 as of Friday - than any state, but has seen a decline in demand for the vaccine, which Ashley attributed to discomfort people may feel answering intrusive questions about their behaviors or sharing other identifying details. (
  • Some people claim that the testing of the vaccines was rushed, but that's not true. (
  • Some people claim that the testing of the vaccines was rushed. (
  • That means more than 30,000 people in the case of Astra and more than 40,000 in the case of Pfizer were randomly allocated to receive either a vaccine or a placebo. (
  • In the case of Astra, the good news was that UK studies found that while the vaccine was 60% effective at preventing mild disease, it was 92% effective at protecting people from becoming sick enough to require hospitalisation. (
  • People who are moderately or severely immunocompromised have different recommendations for COVID-19 vaccines , including boosters. (
  • GENEVA - The World Health Organization chief on Monday lambasted drugmakers' profits and vaccine inequalities, saying it's "not right" that younger, healthier adults in wealthy countries get vaccinated against COVID-19 before older people or health care workers in poorer countries and charging that most vaccine makers have targeted locations where "profits are highest. (
  • This led to anti-vax conspiracy theorists forming the belief and spreading the rumor that Gates was implanting chips in vaccines to track people. (
  • Women's longer life spans also mean that older people in the first rounds of vaccine eligibility were more likely to be female. (
  • Some break down the statistics by total vaccine doses, for example, while others report people who have gotten at least one dose. (
  • That data shows the gap has narrowed but hasn't disappeared as vaccine eligibility has expanded beyond people in long-term care and health care workers. (
  • In South Carolina , for example, the gender breakdown of vaccine recipients as of April 4 was slightly wider for younger people: 61% of vaccinated people ages 25-34 were women compared with 57% female for age 65 and older. (
  • mRNA COVID-19 vaccines were not associated with significantly higher rates of 23 serious adverse events 1 to 21 days after receiving one or two doses than after 22 to 42 days, finds an interim analysis of surveillance safety data involving millions of people today in JAMA . (
  • There's also a year of real-world data for this vaccine, which has been administered to tens of millions of people in the US. (
  • White House COVID-19 response team coordinator Jeff Zients on Friday announced that 100 million people in the U.S. have now received their final shot of a COVID-19 vaccine. (
  • What do you want people who are skeptical about getting the vaccine, what do you want them to take away from this documentary? (
  • WKRG ) Mississippi is one of two states that has included smoking on the list of chronic health conditions that make people eligible for the Covid-19 vaccine. (
  • Unless that challenge is met, the problem of meningitis won't be solved because the people who need the vaccine won't be able to afford it. (
  • Despite all this, "health authorities" continue to push the jabs on everyone, including children, even though untold thousands of people are suffering and dying from vaccine adverse effects. (
  • Relatively few health care workers volunteered to get the vaccine, amid concerns that the live vaccinia virus used in the vaccine can be transmitted to other people for a time and can pose a serious risk to people with weakened immune systems and certain skin conditions. (
  • After that point, people in the control groups continued to get COVID (increasing line), while very few cases showed up in the vaccine groups (flat line). (
  • the Moderna vaccine is for people aged 18 and up. (
  • The department's focus, Tau explained, is 'to proactively bring the vaccine to where people already are in the community, removing any barriers and making it as convenient as possible. (
  • Because vaccines are given to millions of healthy people-including children-to prevent serious diseases, they're held to very high safety standards. (
  • FDA uses the information from these tests to decide whether to test the vaccine with people. (
  • Before the arrival of the vaccine, pertussis infected an average of 200,000 people a year in the United States alone. (
  • Considering the fact that thousands of people are dying from the vaccines , Berman's statements are both foolish and moot. (
  • Tucker isn't telling people not to take the vaccines," reported The Right Scoop . (
  • Instead they should rationally address these concerns instead of telling people that you won't be able to grill in your backyard on the fourth of July unless you take the vaccine … That was his point. (
  • Try as they might to denigrate all who question Wuhan coronavirus (Covid-19) vaccines as "anti-vaxxers," these mainstream media talking heads are actually doing a great disservice to the American people by pretending as though this is all just political. (
  • Ironically, CNN and the other fake news outlets that are withholding this critical information from their viewers are the ones trying to kill people by tricking them into thinking that Wuhan coronavirus (Covid-19) vaccines are "safe and effective. (
  • French President Emmanuel Macron said Europe and the U.S. should allocate up to 5% of their current COVID-19 vaccine supplies to the poorest countries "very fast, so that people on the ground see it happening. (
  • The flu vaccine is free for children aged six months to five years, Aboriginal and Torres Strait Islander people, pregnant women and people with medical conditions (such as chronic heart or lung disease, low immunity or diabetes). (
  • This fact sheet has been developed to provide practical advice about the use of this vaccine in children and young people and should be read in addition to the information supplied by the manufacturer which can be found at NPS MedicineWise . (
  • Balducci said people have an easy time figuring out if they're eligible for vaccines. (
  • The Washington State Department of Health even has a quick questionnaire that will determine vaccine eligibility and send notifications when people are able to get it. (
  • The lack of a coordinated effort to sign people up for a vaccine is almost creating a lottery, which she said is mostly due to the lack of doses and the amount fluctuating throughout the rollout. (
  • Balducci said the focus on South King County is important, even if people are struggling to schedule appointments in her own district, as vaccines need to meet the rate of transmission. (
  • Vaccines scare people. (
  • Fully 250 million people in the United States are now eligible for COVID-19 vaccines, and pharmacies can help speed the slower-than-expected vaccine distribution process, said Kathleen Jaeger, senior vice president of pharmacy care and patient advocacy at the National Association of Chain Drug Stores (NACDS), an Alexandria, Virginia-based trade group representing chain pharmacies. (
  • Many people live within five miles of a local pharmacy, so it will be easier to give out the vaccines," she said. (
  • More than 29 million vaccine doses have been distributed so far in the United States, and over 10 million people have received their first dose. (
  • In early safety tests, a few dozen healthy people received either a vaccine or a placebo for comparison. (
  • And then, he added, at least 150 or so people who received the placebo have to get sick in order to have enough cases to compare to those who received the vaccine. (
  • As with any medication, some people may experience an allergic reaction to the COVID-19 vaccine. (
  • As the COVID-19 vaccines continue to be administered across military hospitals and smaller clinics and outposts under Centers for Disease Control and Prevention guidance, the advice from the military and a multitude of national maternal and fetal health professional associations is the same: For most pregnant people, getting the COVID-19 vaccine as soon as possible is the safest choice based on the science to date. (
  • As for those who do not want to take the vaccine, "we know there are significantly increased risks for pregnant people who contract COVID-19, e.g., they are three times more likely to be admitted to the ICU and need breathing support," said Navy Cmdr. (
  • CDC's new recommendations allow an additional updated (bivalent) vaccine dose for adults ages 65 years and older and additional doses for people who are immunocompromised. (
  • People aged ≥ 65 years who received 1 dose of a vaccine have the option to receive 1 additional dose at least 4 months after the first bivalent dose. (
  • In the United States, there are several vaccines that are effective at protecting people from getting seriously ill, being hospitalized, and dying from COVID-19. (
  • [ 3 ] During this same time period, the Novavax vaccine showed 90.4% efficacy. (
  • Novavax is a Maryland-based biotech company that has taken a traditional approach to developing a vaccine against COVID-19. (
  • The Novavax vaccine uses a custom-made spike protein that mimics the natural spike protein in the SARS-CoV-2 virus. (
  • Early vaccine trial results published by Novavax revealed a strong antibody response to the vaccine in animals. (
  • In fact, the virus' continued presence in Africa is largely the result of unequal access to global vaccine stockpiles and health care resources. (
  • The largest global vaccine rollout in history , being intensely scrutinised by health authorities around the world, in order to measure the real risks and benefits of the vaccines. (
  • Jerome Kim, M.D., Director-General of the International Vaccine Institute (IVI), said, "As a UN-chartered international organization, IVI has a unique status in the global vaccine community as an intermediary to have a synergistic, non-redundant relationship with other global health stakeholders and its missions. (
  • Earlier this year, Haiti shrugged off two offers of doses AstraZeneca - first from India and then from COVAX, the global vaccine sharing program . (
  • After weeks of waiting for word on when they would receive the COVID-19 vaccine, residents and staff at Hermitage Northern Virginia, a local retirement community, received a dose of hope on Jan. 14. (
  • Olga, age 76, woke up at 6 a.m. to make the trek from The Bronx to the Fort Washington Armory in Washington Heights Tuesday in hopes of getting the COVID-19 vaccine. (
  • President Joe Biden said Wednesday that he had s igned into a law a bill that aims to expand the distribution of COVID-19 vaccines to military veterans and their families. (
  • Microchips play no role in the development, testing or distribution of COVID-19 vaccines. (
  • Vaccines are undoubtedly the most complex medical products to develop, from concept to a stage where sufficient evidence of quality, safety and efficacy are collected to provide an assurance that their use will provide more benefits than risks when used in the context of a public health emergency. (
  • Efficacy among adults aged 65 to 74 years is approximately 96% for the mRNA vaccines and 84% for Janssen vaccine. (
  • [ 4 ] Vaccine efficacy (VE) has shown to wane over time following an initial 2-dose primary series with the mRNA vaccines and the 1-dose regimen with the Janssen vaccine. (
  • 3. If you are concerned about the exposure or efficacy of any of your vaccine stock, do not administer the vaccine until you have consulted your state or local health department. (
  • Harris said in a CNN interview that she "would not trust Donald Trump" on the safety and efficacy of a vaccine approved before election day. (
  • As for safety, rigorous safety and efficacy standards are set by the FDA for these (and all) vaccines. (
  • 1.4 Heat killed B. pseudomallei vaccine with CLDC adjuvant shows the highest efficacy in mice models following inhalation challenge thus far ( 1 ). (
  • Older children , adolescents , and adults also need 1 or 2 doses of MMR vaccine if they are not already immune to measles, mumps, and rubella. (
  • ROCHESTER, Minn. - Feb. 27, 2014 - Somali Americans develop twice the antibody response to rubella from the current vaccine compared to Caucasians in a new Mayo Clinic study on individualized aspects of immune response. (
  • A non-Somali, African-American cohort ranked next in immune response, still significantly higher than Caucasians, and Hispanic Americans in the study were least responsive to the vaccine. (
  • They found no difference in gender-a surprise, says Dr. Poland, because in most studies women consistently have a better immune response to vaccines than men. (
  • Vaccines are injections (shots), liquids, pills, or nasal sprays that you take to teach your body's immune system to recognize and defend against harmful germs. (
  • Vaccines work in different ways, but they all spark an immune response. (
  • And for a few vaccines, getting vaccinated can actually give you a better immune response than getting the disease would. (
  • For example, they may not be able to get a vaccine because they have weakened immune systems. (
  • CDC recommends that anyone ages 5 and older who have moderately or severely weakened immune systems (immunocompromised) get a third dose of vaccine. (
  • But a significant limitation of developing a cancer vaccine versus developing a vaccine to a bacterium, for example, is that while bacteria are totally foreign entities, completely made of non-human proteins, tumour cells retain most of the endogenous proteins and are thus mostly tolerated by the immune system. (
  • It is worth noting that melanoma is especially amenable to a neoantigen vaccine approach owing to its heavy mutation burden, which facilitates neoantigen identification and makes the tumour inherently more susceptible to an antigen-specific immune response. (
  • Perhaps more importantly, it can be expected that cancer vaccines complement other immunotherapy modalities well - particularly immune checkpoint blockade, as the two approaches follow orthogonal immune mechanisms. (
  • Indeed, the two studies suggest a benefit from combining either vaccine formulation with immune checkpoint inhibition. (
  • [ 16 ] Autoimmune diseases such as lupus have also garnered attention due to the potential of anti-idiotype vaccines to "fine tune" an immune system which has lost its proper controls. (
  • Finally, pioneering studies are testing the utility of DNA vaccines as methods of increasing a cancer victim's immune response to malignant cells. (
  • Patient's with melanoma, mesothelioma, renal cell cancer and breast cancer are being treated with gene transfer vaccines engineered to express proteins which stimulate the body's immune response to cancer cells. (
  • Nanoemulsion vaccines are highly effective at penetrating the mucous membranes in the nose and initiating strong and protective types of immune response, Baker says. (
  • Anna U. Bielinska, Ph.D., a research assistant professor in internal medicine at the U-M Medical School, and others on Baker's research team developed a killed-vaccinia virus nanoemulsion vaccine which they placed in the noses of mice to trigger an immune response. (
  • There is growing interest in vaccines that induce mucosal immunity, in which the immune system stops and kills the invader in mucous membranes before it enters body systems. (
  • The basic strategies behind the use of vaccines to prepare the human immune system. (
  • Antigens are the part of viruses (and vaccines) that spur our immune systems into action, according to the World Health Organization (WHO). (
  • A true universal vaccine for flu, however, would induce immunity to proteins that are the same in all flu viruses, but which flu normally hides from the immune system. (
  • Yesterday's article, Vaccines Do Irreparable Harm: Study from Poland , documents the revealing information brought out by Polish scientists' review of the scientific literature on vaccination's adverse effects and immune system effects. (
  • Their immune system is such that it is not safe to give them certain vaccines are vaccines will not work for them. (
  • All previous vaccines have triggered the immune system with dead or weakened versions of a germ or parts of it. (
  • He noted the WHO-backed COVAX program, which aims to get vaccines out to all countries, rich or poor, based on need, has so far secured 2 billion vaccine doses from five producers and options on a billion doses more. (
  • Even though IVI didn't have its own Covid-19 vaccines, it managed to contribute over a billion doses of Covid-19 vaccine to COVAX, accounting for about 20 percent of the total. (
  • Biden has pledged to join the COVAX initiative, and the White House says he will emphasize the need for global coordination on vaccine production, distribution and supplies when he speaks at Friday's G-7 meeting. (
  • 1 Section for Therapeutic Vaccines, Division for Immunology, Paul-Ehrlich-Institut, Paul-Ehrlich-Str. (
  • In this short video, Dr. Paul Offit describes what the COVID-19 bivalent vaccines are and who might need them as a booster. (
  • Paul Offit argues that it's unconscionable to let unvaccinated kids get and transmit measles and other vaccine-preventable diseases. (
  • Paul Offit responds to a column in the New York Times that claims there is a 'conspiracy of silence' among vaccine scientists about the harms of vaccines. (
  • Dr Paul Offit compares Shingrix with Zostavax® and lays out the recommendations for the new vaccine. (
  • Lives Are Saved Even With a 'Less Effective' Vaccine Dr Paul Offit explains the various ways the flu virus can mutate away from the strains in the vaccine, as it has in the 2017-2018 season. (
  • Fading Immunity May Be Behind Mumps Epidemic Dr Paul Offit discusses potential weaknesses in the MMR vaccine, and ongoing efforts to address them. (
  • The HPV Vaccine and Autoimmunity: Reviewing the Research Paul Offit reviews the evidence to respond to reader concerns about autoimmune conditions and the HPV vaccine. (
  • Priming with whole-cell and then finishing with acellular pertussis vaccine would better protect children from pertussis, says Paul Offit. (
  • Dr Paul Offit provides advice on using up existing stock of HPV-4 vaccine now that a 'better' HPV-9 vaccine is available. (
  • Vaccines are important because they protect you against many diseases. (
  • Vaccines stop diseases safely - why all the suspicion? (
  • Despite the availability of effective vaccines against common childhood infections a significant number of children under five years of age continue to die from communicable diseases. (
  • Vaccines that work against all flu strains could eventually be given once in childhood, like vaccines for other diseases. (
  • The new Vaccine technologies against transmissible and non-transmissible diseases, such as cancer, have had an impact on international public health. (
  • The development and use of aquatic vaccines are the safest and most effective ways to prevent aquatic animal diseases and preserve the health and sustainability of aquaculture . (
  • He's the notorious perpetrator of the myth linking autism with the measles, mumps and rubella vaccine, a stance that got Wakefield's medical license revoked in Britain and that has caused needless disease and suffering in Britain, across Europe and in the U.S. (
  • The introduction of a rubella vaccine in 1969 has greatly reduced the incidence of congenital rubella syndrome in the developed world. (
  • Children younger than nine years of age who are receiving the vaccine for the first time, require two doses given at least four weeks apart. (
  • The two vaccines currently in use require two doses. (
  • The vaccines require two doses, and 'not everybody has been recruited to get dose one yet. (
  • In the United States, the Centers for Disease Control and Prevention (CDC) publishes the vaccine schedule. (
  • The only other existing cholera-prevention vaccines require 2 doses, according to the Centers for Disease Control and Prevention (CDC). (
  • As a nation, Thailand needs a comprehensive vaccine plan from technology creation, technology transfer, and research centers to industrial-scale manufacturing facilities and human resource development. (
  • CISA is a collaboration between CDC and a national network of vaccine safety experts from medical research centers. (
  • The U.S. Centers for Disease Control and Prevention has information on where and when you can get your COVID-19 vaccine. (
  • Guidance from the U.S. Centers for Disease Control and Prevention (CDC) says public health agencies should be ready to distribute a vaccine by November 1, shortly before the presidential election. (
  • Nationwide, 77% of Americans aged five and up have at least one dose of vaccine, according to the Centers for Disease Control and Prevention (CDC). (
  • In general, the rationale for vaccine mandates is public health: Public school children are required to get vaccinated for measles, for instance, in order to prevent the spread of measles to other, more vulnerable individuals. (
  • Other major cities, including New York, San Francisco and Boston had previously announced similar vaccine mandates for indoor activities. (
  • In the first week of the vaccine rollout, 614,000 Americans were vaccinated but nearly 1.5 million were diagnosed with COVID-19. (
  • If everyone adhered to these simple and small actions, the short-term impact would be much greater than that of the vaccine rollout. (
  • In fact, the Institute for Health Metrics and Evaluation projects that over the next three months universal mask wearing alone could save 49,000 lives, while the vaccine rollout would save 33,200. (
  • Vaccine distributors across the US have collectively discarded over 82.1 million doses of COVID-19 vaccines from. (
  • CDC recommends that everyone ages 6 years and older receive an updated (bivalent) mRNA COVID-19 vaccine, regardless of whether they previously completed their (monovalent) primary series. (
  • A main challenge in taking cancer vaccines mainstream will be optimizing the complex manufacturing pipeline that enables personalization. (
  • WASHINGTON - The nation's third vaccine to prevent COVID-19 was being shipped across the U.S. Monday, fueling more hope in the race against a virus that already has killed more than 513,000 Americans and is mutating in increasingly worrisome ways. (
  • So getting immunity from a vaccine is safer than getting immunity by being sick with the disease. (
  • Community immunity, or herd immunity, is the idea that vaccines can help keep communities healthy. (
  • A vaccine is a biological preparation that improves immunity to a particular disease. (
  • They found the vaccine produced both mucosal and antibody immunity, as well as Th1 cellular immunity, an important measure of protective immunity. (
  • We found that the nanoemulsion vaccine could inactivate and kill the virus and then subsequently induce immunity to the virus that includes cellular immunity, antibody immunity and mucosal immunity," Baker says. (
  • JE viruses isolated from human cases in Japan in 1935 and in Beijing in 1949 provided the prototype Nakayama, Beijing and P3 strains respectively that are in principal use in vaccine production. (
  • The film follows five research groups as they forgo sleep and family time to develop vaccines using approaches ranging from tried-and-true inactivated viruses to cutting-edge messenger RNA techniques. (
  • Because this research does not require replicating "live" viruses, it does not need to be done in high-level containment facilities when developing vaccines for highly pathogenic viruses. (
  • The exceptional speed of COVID-19 vaccine development is due to years of prior research on other viruses, including coronaviruses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). (
  • These vaccines contain no live viruses that could directly infect a mother or baby. (
  • The COVID-19 vaccines approved for use in the UK have met strict standards of safety, quality and effectiveness. (
  • Analyzes the cost-benefit and cost-effectiveness of different vaccine options. (
  • Throughout the process, FDA works closely with the company producing the vaccine to evaluate the vaccine's safety and effectiveness. (
  • The COVID-19 vaccine was developed in approximately 1-year and many have their doubts about its safety and effectiveness. (
  • Because of the urgency of the situation and the evidence supporting vaccine safety and effectiveness, the U.S. government provided funding for vaccine manufacture before FDA approval. (
  • Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic review and meta-analysis. (
  • Encouraging information, counseling and continuing education is recommended as a strategy to broaden vaccine acceptance in order to sediment its implementation and ensure effectiveness in reducing new cases of cervical cancer in the future. (
  • This same logic does not hold for the COVID-19 vaccines, which have largely failed to prevent the spread of infection, particularly for the COVID-19 variants. (
  • New coronavirus variants have cropped up in the U.S.and vaccine makers are readying themselves in case regulators call for changes to their recipe. (
  • KUOW Reporter Kate Walters joins Soundside to get us up to speed on the new vaccine boosters that target Omicron variants. (
  • But a growing problem for these cash-strapped nations is that the current rabies vaccines, which contain inactive versions of the deadly virus, are expensive to produce. (
  • In Kentucky , for instance, 64% of residents who had received at least one dose of vaccine by early February were women and 36% were men. (
  • Individuals aged 12 and older will have to have received one dose of vaccine to be in compliance with the order. (
  • That's when nine companies involved in the race to develop a vaccine issued a joint statement promising to "uphold the integrity of the scientific process" as they work toward seeking government approval. (
  • And moreover, how would the partnership be able to develop a vaccine that the countries of the meningitis belt could afford? (
  • Our challenging target is to develop a vaccine in 100 days, from pathogen identification to having a vaccine available for use. (
  • Scientific/academic institutions and manufacturers started to work on the development of Covid-19 vaccines only after the declaration of the PHEIC. (
  • It was an important development for COVID vaccines since it suggested that it may help reduce both infection and transmission rates. (
  • Lack of government coordination: In a number of African countries vaccine research and development is not well coordinated. (
  • In a perspective in The Journal of the American Medical Association , the experts highlight innovations that could significantly shorten the typical decades-long vaccine development timeline. (
  • Platform technologies enable scientists to apply a standardized manufacturing process to multiple vaccines and create a collective database on their safety as well, which can shorten the preclinical development period to as little as several months, according to the authors. (
  • From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. (
  • This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. (
  • In the 2000s there was misinformation about vaccines, which falsely claimed vaccines were related to development of autism in children. (
  • A year later, the Bill & Melinda Gates Foundation provided a ten-year grant to establish the Meningitis Vaccine Project (MVP), an award-winnning partnership between PATH and WHO that would lead the development, testing, licensure, and widespread introduction of a conjugate vaccine with the promise of protecting millions of lives from group A meningococcal meningitis. (
  • Staff held information sessions with residents and team members to provide clear information about the vaccine development process and any associated side effects or risks. (
  • Vaccine development takes time. (
  • IVI provides translation and support services to accelerate vaccine development. (
  • In conclusion, TD is a threat to military efficiency, and development of enteric vaccines is said to be a priority for the US Army. (
  • With the development of vaccines against polio, the rates have gone down by more than 99 percent. (
  • The golden age of vaccine development did not come until after World War II, when several new vaccines were developed in a relatively short period. (
  • Spearheaded by Operation Warp Speed, the government's vaccine development program, this plan will ultimately allow more than 40,000 pharmacies across the nation to inject 100 million vaccines in a month's time. (
  • Two COVID-19 vaccines that could arrive as soon as November use a promising new technique that experts say speeds up the development process. (
  • This page lists emerging information and publications in COVID-19 Genomics and Precision Health portal that are relevant to vaccine development, evaluation, implementation and impact. (
  • Current status and development prospects of aquatic vaccines. (
  • To give references for the development and implementation of aquatic vaccines , this study reviews the development history , types, inoculation techniques , mechanisms of action, development prospects, and challenges encountered with aquatic vaccines . (
  • Even the head of Trump's Operation Warp Speed vaccine drive, former drug executive Moncef Slaoui, has expressed doubts that the recruitments and analysis of trial results can be completed to meet that deadline. (
  • It turns out that Donald "father of the vaccine" Trump's "Operation Warp Speed" injections are six times more harmful to males than they are to females, at least as far as cardiovascular events are concerned. (
  • Health Secretary Sajid Javid, on other hand, is all about jabbing young boys and girls with Trump vaccines at "warp speed. (
  • The Oxford/AstraZeneca vaccine contains a tiny amount of alcohol, but this is less than in some everyday foods like bread. (
  • Taipei, March 17 (CNA) The government aims to start administering the AstraZeneca COVID-19 vaccine next Monday at the soonest after the drug cleared required testing Wednesday, according to Minister of Health and Welfare Chen Shih-chung (陳時中). (
  • CECC spokesman Chuang Jen-hsiang (莊人祥) said the center's meeting in Taipei will look at the reasons why some countries have suspended administration of the AstraZeneca vaccine and study any recommendations put forth by the EMA. (
  • Taiwan received its first batch of COVID-19 vaccine, comprising 117,000 AstraZeneca doses, on March 3. (
  • It's important for both children and adults to get their vaccines according to the schedule. (
  • In April, the non-profit Kaiser Family Foundation, based in San Francisco, California, found that 54% of US adults either believe common misinformation about COVID-19 vaccines or think that it might be true (see ). (
  • Safety and immunogenicity of homologous versus heterologous booster dose with AZD1222, mRNA-1273, or MVC-COV1901 SARS-CoV-2 vaccines in adults: An observer-blinded, multi-center, phase 2 randomized trial. (