Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Hybrid capture II, a new sensitive test for human papillomavirus detection. Comparison with hybrid capture I and PCR results in cervical lesions. (1/6661)
AIM: To test a new assay for the detection of human papillomavirus (HPV) DNA, hybrid capture II (HC II), compared with the previous commercialized hybrid capture I (HC I) and polymerase chain reaction (PCR) results on cervical scrapes from fresh cone excision biopsy samples. METHODS: The three methods were used on cervical scrapes from 42 fresh cone excision biopsy samples. There were nine metaplastic and inflammatory lesions, five low grade lesions, and 28 high grade lesions. PCR was performed using the general primers GP5+/GP6+. The viral load of high risk HPV DNA was estimated by the ratio of relative light units to positive control values in the samples. RESULTS: The sensitivity of HC I for the detection of high grade lesions was 71.4%, while it was 92.8% for HC II and 96.4% for the PCR. Considering only the absence of detectable cervical in situ neoplasia, the specificity was 88.9% for HC I, 66.7% for HC II, and 66.7% for PCR. With HC II, for a ratio of cervical sample to normal control of > 200, the sensitivity for the detection of high grade lesion was only 34.6% with a specificity of 66.7%. CONCLUSIONS: HPV detection with the HC II assay is more sensitive than the previous HC I and represents a more convenient and easier test than PCR for routine use. Nevertheless the viral load estimated with this test cannot be a reliable predictive indicator of high grade lesions. (+info)Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection. (2/6661)
AIM: To investigate the immunocytochemical staining pattern of mdm2 and p21WAF1 proteins in invasive cervical cancer and to determine its relation with the expression of p53 and with the high risk HPV infection. METHODS: Immunocytochemistry for p53, mdm2, and p21WAF1 was performed in 31 paraffin embedded sections of invasive cervical cancer. The results were assessed by image analysis, evaluating for each protein the optical density of the immunostained area, scored as percentage of the total nuclear area. The presence of high risk human papillomavirus (HPV) infection was detected by using the polymerase chain reaction. RESULTS: Immunostaining for both mdm2 and p21WAF1 was correlated with p53 expression; however, the correlation between p53 and mdm2 (R = 0.49; p < 0.01) was more significant than between p53 and p21WAF1 (R = 0.31; p < 0.05); the less stringent correlation between p53 and p21WAF1 might reflect the p53 independent mechanisms of p21WAF1 induction. Similar average levels of p53, mdm2, and p21WAF1 immunostaining were found in the presence or absence of high risk HPV-DNA, without significant differences between the two groups. CONCLUSIONS: These data suggest that mdm2 and p21WAF1 proteins are expressed in invasive cervical cancer and that their immunocytochemical staining pattern is not abrogated by the presence of high risk HPV genomic sequences. (+info)Expression of extracellular matrix proteins in cervical squamous cell carcinoma--a clinicopathological study. (3/6661)
AIM: To evaluate the intracellular and peritumoral expression of matrix proteins in squamous cell carcinoma of the uterine cervix using immunohistochemistry. METHODS: 71 squamous cell carcinomas and 10 controls were stained for laminin, fibronectin, and collagen IV. Cytoplasmic staining in tumour cells and peritumoral deposition of matrix proteins were evaluated. The association between staining results and patient age, tumour stage, histological grade, and survival was studied. RESULTS: Positive cytoplasmic staining for laminin, fibronectin, and collagen IV was observed in 17 (23.9%), 27 (38%), and 10 (14.1%) cases, respectively. Staining for laminin was most pronounced in the invasive front of tumour islands, while for fibronectin and collagen IV it appeared to be diffuse. Peritumoral staining for laminin and collagen IV was detected in 12 cases (16.9%). Early stage (Ia1-Ia2) tumours were uniformly negative for all three proteins. Cytoplasmic staining for laminin correlated with positive staining for fibronectin and collagen IV, and with the presence of a peritumoral deposition of collagen IV and laminin. There was no correlation with any of the three markers between staining results and patient age, stage, grade, or survival. CONCLUSIONS: Expression of extracellular matrix proteins in some cervical squamous cell carcinomas might reflect the enhanced ability of these tumours to modify the peritumoral stroma. This ability seems to be absent in early stage tumours. The correlation between intracytoplasmic and peritumoral expression of matrix proteins supports the evidence of their synthesis by tumour cells. However, this property did not correlate with disease outcome in this study. (+info)Screening for cervical cancer: a review of women's attitudes, knowledge, and behaviour. (4/6661)
The United Kingdom (UK) cervical screening programme has been successful in securing participation of a high proportion of targeted women, and has seen a fall in mortality rates of those suffering from cervical cancer. There remains, however, a significant proportion of unscreened women and, of women in whom an abnormality is detected, many will not attend for colposcopy. The present work reviews the psychological consequences of receiving an abnormal cervical smear result and of secondary screening and treatment, and examines reasons for women's non-participation in the screening programme. Psychological theories of screening behavior are used to elucidate women's reactions and to suggest methods of increasing participation, of improving the quality of the service, and of reducing women's anxiety. A literature search identified studies that examine factors influencing women's participation in the screening programme, their psychological reaction to the receipt of an abnormal cervical smear result, and experiences of colposcopy. Reasons for non-participation include administrative failures, unavailability of a female screener, inconvenient clinic times, lack of awareness of the test's indications and benefits, considering oneself not to be at risk of developing cervical cancer, and fear of embarrassment, pain, or the detection of cancer. The receipt of an abnormal result and referral for colposcopy cause high levels of distress owing to limited understanding of the meaning of the smear test; many women believe the test aims to detect existing cervical cancer. The quality of the cervical screening service can be enhanced by the provision of additional information, by improved quality of communication, and by consideration of women's health beliefs. This may result in increased participation in, and satisfaction with, the service. (+info)Analysis of TSG101 tumour susceptibility gene transcripts in cervical and endometrial cancers. (5/6661)
Carcinoma of the uterine cervix is a common malignancy among women that has been found to show loss of heterozygosity in the chromosome 11p. Recent studies have localized the TSG101 gene in this region, and also demonstrated a high frequency of abnormalities of this gene in human breast cancer. To determine the role of the TSG101 gene in the carcinogenesis of cervical and uterine carcinoma, 19 cases of cervical carcinoma and five cases of endometrial carcinoma, as well as nearby non-cancerous tissue from the same patients, and 16 blood samples from healthy persons as normal control were analysed by Southern blot analysis of genomic DNA, reverse transcription of the TSG101 mRNA followed by PCR amplification and sequencing of the products. We found that abnormal transcripts of the TSG101 gene were common both in cancerous or non-cancerous tissues of the uterus and cervix and in normal peripheral mononuclear cells. There was no genomic deletion or rearrangement in spite of the presence of abnormal transcripts, and no definite relationship between the abnormal transcripts and HPV infection was found. Although the frequency of abnormal transcripts was higher in cancerous than in non-cancerous tissue, normal peripheral mononuclear cells also had abnormal transcripts. Given these findings, the role of the TSG101 gene as a tumour-suppressor gene should be re-evaluated. Because some aberrant transcripts could be found at the first PCR reaction, we suggest that the aberrant transcripts might be the result of imperfect minor splicesome products. (+info)A possible involvement of aberrant expression of the FHIT gene in the carcinogenesis of squamous cell carcinoma of the uterine cervix. (6/6661)
To investigate involvement of an aberrant expression of the FHIT (fragile histidine triad) gene in the process of carcinogenesis and progression in cervical carcinoma, we examined its expression by the reverse transcriptase polymerase chain reaction (RT-PCR) and cDNA sequence method in 32 cervical invasive carcinomas (25 squamous cell carcinomas and seven adeno- or adenosquamous carcinomas) and 18 of its precursor lesions [four low-grade and 14 high-grade cervical intraepithelial neoplasias (CINs)]. We also examined a link between the occurrence of the aberrant expression and human papillomavirus (HPV). We detected the aberrant FHIT transcripts in 11 of 25 (44%) cervical invasive squamous cell carcinomas and in 5 of 14 (36%) high-grade CINs (CIN 2 or 3), whereas they were not found in seven non-squamous type and four low-grade CINs (CIN 1). The alteration patterns of the FHIT gene expression in high-grade CINs were virtually similar to those found in invasive carcinomas, such that the exons 5-7 were consistently deleted associated or unassociated with loss of the exon 4 and/or 8. The incidence of the aberrant expression was not related to the presence of HPV and its type. These data indicate that the aberrant expression of the FHIT gene is observed in precursor lesions of cervical carcinoma as well as invasive carcinomas, with its incidence not increasing with advance of clinical stage. Given the squamous cell type dominant expression, the aberrant expression may play a critical role in the generation of squamous cell carcinoma of the uterine cervix, but not the consequence of the progression of the cancer. (+info)Modulation of the cytotoxicity of 3'-azido-3'-deoxythymidine and methotrexate after transduction of folate receptor cDNA into human cervical carcinoma: identification of a correlation between folate receptor expression and thymidine kinase activity. (7/6661)
Cervical carcinoma is an AIDS-defining illness. The expression of folate receptors (FRs) in cervical carcinoma (HeLa-IU1) cells was modulated by stable transduction of FR cDNA encapsidated in recombinant adeno-associated virus-2 in the sense and antisense orientation (sense and antisense cells, respectively). Although sense cells proliferated slower than antisense or untransduced cells in vivo and in vitro in 2% (but not 10%) FCS, [methyl-3H]thymidine incorporation into DNA was significantly increased in sense cells in 10% serum; therefore, the basis for this discrepancy was investigated. The activity of thymidine kinase (TK) was subsequently directly correlated with the extent of FR expression in single cell-derived clones of transduced cells. This elevated TK activity was not a result of recruitment of the salvage pathway based on the presence of adequate dTTP pools, normal thymidylate synthase (TS) activity, persistence of increased thymidine incorporation despite the exogenous provision of excess 5,10-methylene-tetrahydrofolate, and documentation of adequate folates in sense cells. The increase in TK activity conferred significant biological properties to sense cells (but not antisense or untransduced cells) as demonstrated by augmented phosphorylation of 3'-azido-3'-deoxythymidine (AZT) and concomitantly greater sensitivity to the cytotoxic effects of AZT. Conversely, sense cells were highly resistant to methotrexate, but this was reversed by the addition of AZT. The direct correlation of FR expression and TK activity indicates a previously unrecognized consequence of FR overexpression. (+info)Cervicovaginal human papillomavirus infection in human immunodeficiency virus-1 (HIV)-positive and high-risk HIV-negative women. (8/6661)
BACKGROUND: Human papillomavirus (HPV) infection is associated with precancerous cervical squamous intraepithelial lesions commonly seen among women infected with human immunodeficiency virus-1 (HIV). We characterized HPV infection in a large cohort of HIV-positive and HIV-negative women participating in the Women's Interagency HIV Study to determine the prevalence of and risk factors for cervicovaginal HPV infection in HIV-positive women. METHODS: HIV-positive (n = 1778) and HIV-negative (n = 500) women were tested at enrollment for the presence of HPV DNA in a cervicovaginal lavage specimen. Blood samples were tested for HIV antibody status, level of CD4-positive T cells, and HIV RNA load (copies/mL). An interview detailing risk factors was conducted. Univariate and multivariate analyses were performed. RESULTS: Compared with HIV-negative women, HIV-positive women with a CD4+ cell count of less than 200/mm3 were at the highest risk of HPV infection, regardless of HIV RNA load (odds ratio [OR] = 10.13; 95% confidence interval [CI] = 7.32-14.04), followed by women with a CD4+ count greater than 200/mm3 and an HIV RNA load greater than 20,000 copies/mL (OR = 5.78; 95% CI = 4.17-8.08) and women with a CD4+ count greater than 200/mm3 and an HIV RNA load less than 20,000 copies/mL (OR = 3.12; 95% CI = 2.36-4.12), after adjustment for other factors. Other risk factors among HIV-positive women included racial/ethnic background (African-American versus Caucasian, OR = 1.64; 95% CI = 1.19-2.28), current smoking (yes versus no; OR = 1.55; 95% CI = 1.20-1.99), and younger age (age < 30 years versus > or = 40 years; OR = 1.75; 95% CI = 1.23-2.49). CONCLUSIONS: Although the strongest risk factors of HPV infection among HIV-positive women were indicators of more advanced HIV-related disease, other factors commonly found in studies of HIV-negative women, including racial/ethnic background, current smoking, and age, were important in HIV-positive women as well. (+info)
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Plus it
Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening.
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P16
... infection and neoplasms of cervical origin. The majority of SCCs of uterine cervix express p16. However, p16 can be expressed ... p16 can be used as a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia ( ... p16 immunohistochemical expression alone cannot be used to discriminate between SCCs arising from uterine cervix versus urinary ... CIN). p16 is also implicated in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar ...
MORT (long non-coding RNA)
... and Uterine Corpus Endometrial Carcinoma. MORT is silenced in cervical cancer and therefore may serve as an independent ... lymphoid neoplasm diffuse large B-cell lymphoma, pancreatic adenocarcinoma, rectum adenocarcinoma, skin cutaneous melanoma, ... Factor of low-expressed LncRNA ZNF667-AS1 for cervical cancer and inhibitory function on the proliferation of cervical cancer ...
Florid cutaneous papillomatosis
... uterine cancer, prostate cancer[citation needed], lung cancer and cervical cancer. Other associated underlying malignancies ... It is likely directly induced by an underlying neoplasm secreting a growth factor. One candidate may be alpha-transforming ... Acanthosis Nigricans and Florid Cutaneous Papillomatosis in a Patient with Metastatic Cervical Cancer", Dermatol Sin, 22: 142- ...
Urogenital neoplasm
Types include: Cancer of the female genital organs: (Cervical cancer, Endometrial cancer, Ovarian cancer, Uterine cancer, ... A urogenital neoplasm is a tumor of the urogenital system. ... Neoplasm stubs, Disease stubs, Genitourinary system stubs). ...
Hematometra
... and cervical cancer. Additionally, hematometra may develop as a complication of uterine or cervical surgery such as endometrial ... a biopsy of endometrial tissue can be taken to test for the presence of a neoplasm (cancer). Antibiotics may be given as ... Hematometra is usually treated by surgical cervical dilation to drain the blood from the uterus. Other treatments target the ... Other causes are acquired, such as cervical stenosis, intrauterine adhesions, endometrial cancer, ...
Adolf Gusserow
In 1870 Gusserow was the first physician to describe a rare type of uterine cervical adenocarcinoma that is sometimes referred ... Among his better written efforts was Die Neubildungen des Uterus (Neoplasms of the uterus). Zur Lehre vom Stoffwechsel des ... Cytologic and Cytochemical features of Adenoma Malignum of the Uterine Cervix Libri.de (short biography of Adolf Gusserow) ( ...
Adenosarcoma
Symptoms of cervical adenosarcoma, like uterine adenosarcoma, are characterized by abnormal bleeding. Treatment mainly consists ... Malignant neoplasms arising in endometriosis: clinicopathological study of 14 cases. Clin Exp Obstet Gynecol. 2004;31(4):302-4 ... Uterine adenosarcoma are a subtype of uterine sarcomas. Uterine sarcomas account for 3 to 9% of uterine cancers, and 5.5 to 9% ... Uterine adenosarcoma commonly arise from the endometrium. Uterine adenosarcomas have the highest incidence in perimenopausal ...
Cervical cancer
Myung SK, Ju W, Kim SC, Kim H (October 2011). "Vitamin or antioxidant intake (or serum level) and risk of cervical neoplasm: a ... "Radical trachelectomy and pelvic lymphadenectomy with uterine preservation in the treatment of cervical cancer". American ... Stage 1A cervical cancer Stage 1B cervical cancer Stage 2A cervical cancer Stage 2B cervical cancer Stage 3B cervical cancer ... Cervical intraepithelial neoplasia, the potential precursor to cervical cancer, is often diagnosed on examination of cervical ...
Dyskaryosis
Cervical dyskaryosis is classified into three degrees of severity: mild dyskaryosis, moderate and severe. A further category is ... This may be followed by the development of a malignant neoplasm. Dyskaryosis is used synonymously with dysplasia, which is the ... ". "Dyskaryosis" is a term used for all squamous mucosal surfaces and commonly used for the uterine cervix condition in which ... Dyskaryosis means abnormal nucleus and refers to the abnormal epithelial cell which may be found in cervical sample. It is ...
List of MeSH codes (C13)
... uterine cervical incompetence MeSH C13.371.852.150.131 - uterine cervical neoplasms MeSH C13.371.852.150.150 - uterine ... uterine cervical diseases MeSH C13.371.852.150.074 - uterine cervical dysplasia MeSH C13.371.852.150.112 - uterine cervical ... uterine cervical neoplasms MeSH C13.371.852.833 - uterine prolapse MeSH C13.371.852.904 - uterine rupture MeSH C13.371.852.904. ... uterine cervical neoplasms MeSH C13.371.820.800.418.937 - vaginal neoplasms MeSH C13.371.820.800.418.968 - vulvar neoplasms ...
Glassy cell carcinoma of the cervix
"Uterine Neoplasms". Journal of the National Comprehensive Cancer Network. 7 (5): 498-531. doi:10.6004/jnccn.2009.0035. ISSN ... Cervix Cervical cancer Villoglandular adenocarcinoma Low mag. High mag. Nasu, K.; Takai, N.; Narahara, H. (Jun 2009). " ... 2004). "Glassy cell carcinoma of the uterine cervix a rare histology. Report of three cases with a review of the literature". ... Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour of the uterine cervix. ...
List of cancer types
... islet cell Rectal cancer Small intestine cancer Bladder cancer Cervical cancer Endometrial cancer Extragonadal germ cell tumor ... transitional cell cancer Urethral cancer Uterine sarcoma Vaginal cancer Vulvar cancer Wilms tumor (nephroblastoma) Esophageal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ...
Carcinoma in situ
Cervical squamous intraepithelial lesion (SIL), previously called cervical intraepithelial neoplasia (CIN), is a form of ... Dysplasia of the uterine cervix is removed by excision (cutting it out) or by burning with a laser. Bowen's disease of the skin ... While they are a form of neoplasm, there is disagreement over whether CIS should be classified as cancer. This controversy also ... "Understanding Cervical Changes" (PDF). National Cancer Institute. National Institute of Health. Retrieved 17 June 2014.[ ...
Obstetrical bleeding
... neoplasm, most commonly cervical cancer, and hematologic disorders. Molar pregnancy (also called hydatiform mole) is a type of ... Besides placenta previa and placental abruption, uterine rupture can occur, which is a very serious condition leading to ... As well as cervical insufficiency defined as a midtrimester (14th-26th week) dilation of the cervix which may need medical ... Causes of bleeding before and during childbirth include cervicitis, placenta previa, placental abruption and uterine rupture. ...
MAGEA4
2003). "Expression of cancer/testis tumor associated antigens in cervical squamous cell carcinoma". Oncology. 64 (4): 443-9. ... "Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens in serous ovarian neoplasms". Clinical Cancer Research. 9 (17): ... "Cancer-testis antigen expression in uterine malignancies with an emphasis on carcinosarcomas and papillary serous carcinomas". ...
List of MeSH codes (C04)
... uterine cervical neoplasms MeSH C04.588.945.418.955 - vaginal neoplasms MeSH C04.588.945.418.968 - vulvar neoplasms MeSH ... genital neoplasms, female MeSH C04.588.945.418.365 - fallopian tube neoplasms MeSH C04.588.945.418.948 - uterine neoplasms MeSH ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ...
Small-cell carcinoma
Brown-Séquard syndrome Cervical cancer "small-cell carcinoma" at Dorland's Medical Dictionary Nasu K, Hirakawa T, Okamoto M, ... Small-cell carcinoma is an undifferentiated neoplasm composed of primitive-appearing cells. As the name implies, the cells in ... March 2011). "Advanced small cell carcinoma of the uterine cervix treated by neoadjuvant chemotherapy with irinotecan and ...
Polyp (medicine)
A cervical polyp is a common benign polyp or tumor on the surface of the cervical canal. They can cause irregular menstrual ... Some polyps are tumors (neoplasms) and others are non-neoplastic, for example hyperplastic or dysplastic, which are benign. The ... ISBN 978-1-900151-51-1. "Uterine polyps". MayoClinic.com. 2006-04-27. Retrieved 2007-10-20. Sternberg, Stephen S.; Stacey E. ... An endometrial polyp or uterine polyp is a polyp or lesion in the lining of the uterus (endometrium) that takes up space within ...
List of skin conditions
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... cervical accessory tragus, wattle) Congenital erosive and vesicular dermatosis Congenital hypertrophy of the lateral fold of ... Multinucleate cell angiohistocytoma Multiple cutaneous and uterine leiomyomatosis syndrome (leiomyomatosis cutis et uteri, ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ...
Uterus
... inflammation of the muscular uterine wall. Uterine malformations are mainly congenital malformations, and include uterine ... Prolapse of the uterus Carcinoma of the cervix - malignant neoplasm Carcinoma of the uterus - malignant neoplasm Fibroids - ... "Cervical Stenosis - Women's Health Issues - Merck Manuals Consumer Version". Merck Manuals Consumer Version. Archived from the ... During pregnancy, the uterine glands and blood vessels in the endometrium further increase in size and number and form the ...
Brachytherapy
14 Cervical cancer can be treated with either LDR, PDR or HDR brachytherapy. Used in combination with EBRT, brachytherapy can ... GammaTile is FDA-cleared to treat newly diagnosed, operable malignant intracranial neoplasms (i.e., brain tumors) and operable ... "High-dose-rate versus low-dose-rate intracavitary therapy for carcinoma of the uterine cervix". Cancer. 94 (1): 117-124. doi: ... Brachytherapy is commonly used in the treatment of early or locally confined cervical cancer and is a standard of care in many ...
Fibroblast activation protein, alpha
... in cervical carcinoma and cervical intraepithelial neoplasm". Anticancer Research. 23 (4): 3195-8. PMID 12926053. Iwasa S, Jin ... and uterine stroma. FAP expression is high in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing ...
Glossary of medicine
The narrow, central cervical canal runs along its entire length, connecting the uterine cavity and the lumen of the vagina. The ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Cervical cancer - is a cancer arising from the cervix. It is due to the abnormal growth of cells that have the ability to ... Brachial plexus - is a network of nerves formed by the ventral rami of the lower four cervical nerves and first thoracic nerve ...
Interventional radiology
Uterine artery embolization (UAE) or uterine fibroid embolization (UFE) Prostate artery embolization (PAE) Pulmonary ... Used to treat patients with radicular symptoms in the cervical, thoracic, lumbar or sacral region. Helps to alleviate pain by ... such as osteoporosis or underlying neoplasm. Analogous to vertebroplasty, the purpose of sacroplasty is to provide ...
Ovarian cancer
They can develop further into a variety of other neoplasms, including choriocarcinoma, yolk sac tumor, and teratoma. They occur ... Histologically, they are similar to intestinal or cervical adenocarcinomas and are often actually metastases of appendiceal or ... CA-125 may also be elevated in benign (non-cancerous) conditions, including endometriosis, pregnancy, uterine fibroids, ... More typically, ovarian squamous cell carcinomas are cervical metastases, areas of differentiation in an endometrioid tumor, or ...
Estrogen (medication)
... in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucous or an appropriate uterine ... "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Alan C. Sartorelli, David G. Johns (eds.). ...
Hysterectomy
Uterus prior to hysterectomy Laparoscopical hysterectomy Cervical stump (white) after removal of the uterine corpus at ... "Peritoneal Dissemination Complicating Morcellation of Uterine Mesenchymal Neoplasms". PLOS ONE. 7 (11): e50058. Bibcode: ... where the uterine lining has grown into and sometimes through the uterine wall musculature. This can thicken the uterine walls ... "Uterine Adenomyosis". Yale Medicine. Retrieved 2022-10-31. Uterine fibroids: Overview. Institute for Quality and Efficiency in ...
Cancer
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... Cervical cancer may require birth by Caesarean section. Radiation to the breast reduces the ability of that breast to produce ... In a few instances, such as advanced uterine cancer, the pregnancy cannot be continued and in others, the patient may end the ... It is used to treat basal cell skin cancer and the very early stages of others like cervical, penile, vaginal, vulvar, and non- ...
Uterine fibroid
Benign neoplasms, Wikipedia medicine articles ready to translate, Uterine tumour). ... Cervical fibroids are located in the wall of the cervix (neck of the uterus). Rarely, fibroids are found in the supporting ... The prevalence of uterine fibroids among teenagers is 0.4%. The incidence of uterine fibroids in Europe is thought to be lower ... Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women with ...
Details for:
Cervical cancer screening in developing countries :
› WHO HQ Library catalog
Uterine cervical neoplasms -- diagnosis -- cytology , Diagnostic techniques, Obstetrical and gynecological -- utilization , ... Cervical cancer screening in developing countries : report of a WHO consultation. By: WHO Consultation on Cervical Cancer ...
Browsing Publications by Subject "Uterine Cervical Neoplasms"
Ver por tema "Uterine Cervical Neoplasms"
Accelerating cervical cancer elimination: report by the Director-General Executive Board, 144 (World Health Organization, ... Advocacy for cervical cancer prevention and control in Africa: facilitator manual World Health Organization. Regional Office ... Accelerating the elimination of cervical cancer as a global public health problem: report by the Director-General ... Accelerating the elimination of cervical cancer as a global public health problem: draft decision proposed by Australia, Brazil ...
Results of search for 'su:{Uterine Cervical Neoplasms}' › WHO HQ Library catalog
Results of search for su:{Uterine Cervical Neoplasms} Refine your search. *. Availability. * Limit to currently available ... Screening for cancer of the uterine cervix / from the IARC Working Group on Cervical Cancer Screening and the UICC Project ... Second cancer in relation to radiation treatment for cervical cancer / from the International Radiation Study Group on Cervical ... Cervical screening : a practical guide / Ann McPherson. by McPherson, Ann.. Material type: Text; Format: print Publication ...
UTERINE CERVICAL NEOPLASMS | SelfDecode | Genome Analysis
Cervical Cancer | HPV | Human Papillomavirus | MedlinePlus
Most cervical cancer is caused by the HPV virus. It can often be cured if found early - learn how. ... ClinicalTrials.gov: Uterine Cervical Neoplasms (National Institutes of Health) Journal Articles References and abstracts from ... Cervical Cancer Symptoms (National Cancer Institute) Also in Spanish * Signs and Symptoms of Cervical Cancer (American Cancer ... Cervical Cancer Stages (National Cancer Institute) Also in Spanish * How Is Cervical Cancer Diagnosed? (American Cancer Society ...
Cancer du col de l'utérus
DeCS 2006 - Changed terms
Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric...
Long-term use of oral contraceptives could be a cofactor that increases risk of cervical carcinoma by up to four-fold in women ... who are positive for cervical HPV DNA. In the absence of worldwide information about HPV status, extra effort should be made to ... Uterine Cervical Neoplasms / chemically induced * Uterine Cervical Neoplasms / etiology* Substances * Contraceptives, Oral, ... We aimed to assess how use of oral contraceptives affected risk of cervical cancer in women who tested positive for HPV DNA. ...
AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody...
Uterine Cervical Neoplasms. Uterine Neoplasms. Genital Neoplasms, Female. Urogenital Neoplasms. Neoplasms by Site. Neoplasms. ... Assessment of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Cervical Cancer ... in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer. The safety and scientific validity of this ... in participants with previously treated recurrent or metastatic cervical cancer. ...
Multimedia | Portal Regional da BVS
Cytokine Regulation of Natural Killer Receptors in Inhibiting Activated T Cell Function
Subject: antineoplastic agents / Subject term: antineoplastic activity / Text Availability: Citation in PubAg - PubAg Search...
... pancreatic neoplasms; pollution; research; soybeans; stomach neoplasms; temperature; uterine cervical neoplasms. Abstract:. ... neoplasm cells; stomach; therapeutics; thioredoxins; toxicity; uterine cervical neoplasms. Abstract:. ... Emerging studies ... colorectal neoplasms; comparative study; drug therapy; esophageal neoplasms; glutamine; human health; liver neoplasms; neoplasm ... antineoplastic activity; antineoplastic agents; biosynthesis; breast neoplasms; colorectal neoplasms; humans; lung neoplasms; ...
Comprehensive Cervical Cancer Prevention in Tanzania - Publikationer
- Syddansk Universitet
Uterine Cervical Neoplasms 76% * Nurses 40% * Africa South of the Sahara 30% ... Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study: Cohort profile. Mchome, B., Swai, P., Wu, C., Katanga, J. ... HPV types, cervical high-grade lesions and risk factors for oncogenic human papillomavirus infection among 3416 Tanzanian women ... Competing needs: A qualitative study of cervical cancer screening attendance among HPV-positive women in Tanzania. Linde, D. S. ...
Benign Cervical Lesions: Embryology, Anatomy, Physiology
These benign neoplasms may originate in the cervix and account for approximately 8% of all uterine smooth muscle tumors. They ... These findings include the so-called cockscomb cervix, cervical rings, cervical collars, and cervical hoods. The cockscomb ... The major blood supply is from the descending branch of the uterine artery. Also contributing is the cervical branch of the ... The cervical leiomyoma is usually part of the spectrum of uterine smooth muscle tumors. ...
Associations between religion-related factors and cervical cancer screening among muslims in greater chicago<...
Uterine Cervical Neoplasms Medicine & Life Sciences 69% * Punishment Medicine & Life Sciences 38% ... Padela AI, Peek M, Johnson C, Hosseinian Z, Curlin F. Associations between religion-related factors and cervical cancer ... Padela, AI, Peek, M, Johnson, C, Hosseinian, Z & Curlin, F 2014, Associations between religion-related factors and cervical ... Associations between religion-related factors and cervical cancer screening among muslims in greater chicago. In: Journal of ...
Keith L Knutson - Research output - Mayo Clinic
Portal Regional da BVS
Breast Neoplasms, Vaginal Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, 50234, 50233, Nevi and ... Neoplasms, Medical Oncology, Oncology Service, Hospital, Oncology Nursing, Radiotherapy, Antineoplastic Protocols, ... Antineoplastic Combined Chemotherapy Protocols, Precancerous Conditions, Genetics, Genes, Neoplasm, Neoplastic Stem Cells, ... Genes, Tumor Suppressor, Cancer Symptoms, Biomarkers, Pharmacological, General Surgery, Lung, Lung Neoplasms, Gynecology, ...
Validation of a sustainable internationally monitored cervical cancer screening system using a visual smartphone inspection in...
uterine cervical neoplasms. Data availability statement. Data are available upon reasonable request. ... Conclusions Cervical cancer screening through combined visual inspection, conducted by non-specialized personnel and monitored ... Objective To determine the sensitivity, specificity, and positive and negative predictive values of a cervical cancer screening ... Validation of a sustainable internationally monitored cervical cancer screening system using a visual smartphone inspection in ...
The impact of preventive HPV vaccination.<...
Uterine Cervical Neoplasms Medicine & Life Sciences 55% * Public Health Medicine & Life Sciences 42% ... The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer largely ... N2 - The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer ... AB - The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer ...
Patient 1980,1981,1985,1989,1990
Benign Neoplasms 2140.0 Fibroids and other uterine neoplasms Includes: Myoma Leiomyomata Cervical polyp Nabothian cyst 2145.0 ... Neoplasms Malignant Neoplasms 2100.0 Cancer, gastrointestinal tract Includes: Esophagus Stomach Small intestine Colon 2105.0 ... neoplasm of bone. In other words, change the 20 to V. NOTE: The use of prefixes facilitates the calculation of percent ... Cervical spine, neck Includes: Whiplash 5110.0 Back 5115.0 Knee 5120.0 Ankle 5125.0 Wrist 5130.0 Sprain or strain, other and ...
Drug 1990
Benign Neoplasms 2140.0 Fibroids and other uterine neoplasms Includes: Myoma Leiomyomata Cervical polyp Nabothian cyst 2145.0 ... Fibroids and other uterine neoplasms Includes: Myoma Leiomyomata Cervical polyp Nabothian cyst 2145.0 Other benign neoplasms ... Neoplasms Malignant Neoplasms 2100.0 Cancer, gastrointestinal tract Includes: Esophagus Stomach Small intestine Colon 2105.0 ... Sprains and strains: 5105.0 Cervical spine, neck Includes: Whiplash 5110.0 Back 5115.0 Knee 5120.0 Ankle 5125.0 Wrist 5130.0 ...
Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases...
... and cervical lesions, will be recruited. Seventy-two participants will be randomly allocated to an acupuncture or non-invasive ... Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine ... Eligible for laparotomy with midline incision for gynecological neoplasm including ovarian mass, uterine mass, and cervical ... However, as wound pain is the main target of treatment, the variation of types of neoplasm would not be a great problem. To ...
The AMEDEO Literature Guide
Stephanie Melissa Smith | Stanford Medicine
Uterine Cervical Cancer, Vaginal Cancer, Vulvar Cancer, Trophoblastic Neoplasms, Pelvic Reconstructive Surgery, Neovagina, ... Cause-specific mortality was evaluated in eligible survivors (n = 568), and subsequent malignant neoplasms, chronic health ... Cause-specific mortality was evaluated in eligible survivors (n = 568), and subsequent malignant neoplasms, chronic health ... Cause-specific mortality was evaluated in eligible survivors (n = 568), and subsequent malignant neoplasms, chronic health ...
The Expression of CD8+ and MHC-I in Cervical Cancer with HPV Infection
Neoplasm of the cervical uterine is the most common form neoplasm in women. This neoplasm is found in developing state as ... Cervical cancer is the most common form neoplasm in women. This neoplasm is found in developing state as leading cause of ... Now the pathogenesis of cervical cancer is focused to human papilloma virus (HPV) [1-3]. Immunity to neoplasm or cancer as a ... Immunity against uterine cancer played by MHC-I and CD8+ is in milt category. The experiment that related with uterine cancer ...
CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer<...
Uterine Cervical Neoplasms Medicine & Life Sciences 100% * Immunotherapy Medicine & Life Sciences 95% ... The incidences of cervical carcinoma and of high-grade dysplasia (CIN 3) were consequently reduced by comparison to control ... The incidences of cervical carcinoma and of high-grade dysplasia (CIN 3) were consequently reduced by comparison to control ... The incidences of cervical carcinoma and of high-grade dysplasia (CIN 3) were consequently reduced by comparison to control ...
Three-Year Survival after Lymphadenectomy for Residual Lymph Node Metastasis of Esophageal Cancer with Invasion into the...
MetastasisNeoplasiaLesionsIncidenceDysplasiaBenignVaginalUterusHysterectomyCarcinoma in SPreventionRisk of cervical cancerDevelopment of cervical cancerArtery embolizationAcetic acidSquamous CellCancersMalignantTumorLungOvarianAbnormalSymptomsHysteroscopyProspective studyAntibodiesLeiomyomaEarly Detection
Metastasis2
- Uterine fibroids can also be life threatening via pulmonary metastasis or intravascular extension, despite being benign tumors ( 8 ). (spandidos-publications.com)
- Differences in the integration pattern and episomal forms of human papillomavirus type 16 DNA found within an invasive cervical neoplasm and its metastasis. (omeka.net)
Neoplasia3
- Tissue alterations due to these atrophic changes, trauma, erythema, and microvascularization can be confused with cervical intraepithelial neoplasia. (medscape.com)
- Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine mass, and cervical lesions, will be recruited. (biomedcentral.com)
- Including men and boys in the program was the most effective strategy, reducing the incidence of genital warts, cervical intraepithelial neoplasia, and cervical cancer by 97%, 91%, and 91%, respectively. (cdc.gov)
Lesions3
- Conclusions Cervical cancer screening through combined visual inspection, conducted by non-specialized personnel and monitored by experts through smartphones, shows encouraging results, ruling out high-grade cytological lesions in most cases. (bmj.com)
- The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer largely preventable through Pap screening programs, and now by vaccination with Gardasil. (elsevier.com)
- IMSEAR at SEARO: Role of HSV antibodies in precancerous & cancerous lesions of the uterine cervix--a prospective study. (who.int)
Incidence5
- Several approaches to reduce the incidence of invasive cervical cancers exist. (ox.ac.uk)
- According to the Institute for Health Metrics and Evaluation, the prevalence, incidence and mortality of uterine fibroids worldwide in 2019 were 29, 0.24 and 0.002%, respectively ( 6 ). (spandidos-publications.com)
- Linking cancer incidence data obtained from the Finnish Cancer Registry with this material yielded 32 cases of cervical cancer diagnosed after drawing of the blood sample. (ox.ac.uk)
- Compared with current practice, vaccinating girls before the age of 12 years would reduce the incidence of genital warts (83%) and cervical cancer (78%) due to HPV 6/11/16/18. (cdc.gov)
- Cervical cancer incidence and deaths have substantially decreased in countries with organized cervical cancer screening programs ( 2 ). (cdc.gov)
Dysplasia3
- Cervical Dysplasia: Is It Cancer? (medlineplus.gov)
- The incidences of cervical carcinoma and of high-grade dysplasia (CIN 3) were consequently reduced by comparison to control mice. (elsevier.com)
- Cervical cancer and its dysplasia precursors account for significant morbidity and mortality in women worldwide. (elsevier.com)
Benign2
- Should we perform cervix removal during hysterectomy for benign uterine disease? (bvsalud.org)
- Uterine leiomyoma is the most common benign neoplasm of the female genital tract. (gafacom.website)
Vaginal3
- Also contributing is the cervical branch of the vaginal artery. (medscape.com)
- Presentation is non-specific and often includes abnormal vaginal bleeding and/or discharge, a cervical mass protruding from the vagina, abdominal and/or pelvic pain or, less commonly, difficulty passing stool and perianal pain. (cdc.gov)
- This image depicts a colposcopic view of the vaginal interior, highlighting the cervical erosion that had taken place, due to what turned out to be low grade cervical carcinoma. (cdc.gov)
Uterus1
- The opening of the cervical canal into the uterus is called the internal cervical os. (medscape.com)
Hysterectomy3
- Multiple uterine fibroids and adenomyosis were detected and total hysterectomy was performed. (spandidos-publications.com)
- Management of uterine fibroids includes observation, hormonal therapy, surgery (hysterectomy, myomectomy and trans-cervical resection), uterine artery embolization and high-frequency magnetic resonance-guided focused ultrasound surgery, with appropriate management varying from case to case ( 2-5 ). (spandidos-publications.com)
- In patients who have undergone a radical hysterectomy, lymphovascular space invasion (LVSI), assessed on hematoxylin and eosin-stained slides, is a major factor for adjuvant therapy in patients with cervical cancer. (elsevier.com)
Carcinoma in S1
- We pooled data from eight case-control studies of patients with histologically confirmed invasive cervical carcinoma (ICC) and from two studies of patients with carcinoma in situ (ISC). (nih.gov)
Prevention3
- Thus, an HPV16 E7 immunogen holds promise for noninvasive treatment and prevention of human cervical cancer. (elsevier.com)
- Economic Evaluation of Screening Strategies Combined with HPV Vaccination of Preadolescent Girls for the Prevention of Cervical Cancer in Vientiane, Lao PDR. (ox.ac.uk)
- To determine the cost-effectiveness of screening strategies combined with a vaccination program for 10-year old girls for cervical cancer prevention in Vientiane, Lao PDR. (ox.ac.uk)
Risk of cervical cancer2
- We aimed to assess how use of oral contraceptives affected risk of cervical cancer in women who tested positive for HPV DNA. (nih.gov)
- Background: The ability for women to self-collect human papillomavirus (HPV) samples can potentially reduce the risk of cervical cancer and increase screening coverage. (bvsalud.org)
Development of cervical cancer2
- Human papillomavirus infection is common, preventable, and now widely accepted as the causative agent with oncogenic potential in the development of cervical cancer. (elsevier.com)
- Human papillomaviruses (HPVs) play an important part in the development of cervical cancer, but the role of other infectious agents, such as herpes simplex virus (HSV), is not clear. (ox.ac.uk)
Artery embolization1
- MRI can delineate intramural and submucous myomas accurately and is necessary prior to uterine artery embolization to assess blood flow to the fibroids. (gafacom.website)
Acetic acid1
- Objective To determine the sensitivity, specificity, and positive and negative predictive values of a cervical cancer screening program based on visual inspection with acetic acid and Lugol's iodine using a smartphone in a sub-urban area of very low resources in Kinshasa (Democratic Republic of Congo). (bmj.com)
Squamous Cell3
- Data from a hospital‐based case‐control study collected in 11 participating centers in 9 countries were analyzed to determine whether use of combined oral contraceptives alters risk of invasive squamous‐cell cervical cancer. (illinois.edu)
- The relative risk of invasive squamous‐cell cervical carcinoma was estimated to be 1.31, with a 95% confidence interval that excluded one, in women who ever used combined oral contraceptives. (illinois.edu)
- The strength of these results, and their consistency with those from other studies, suggest that a causal relationship may exist between use of combined oral contraceptives and squamous‐cell cervical carcinoma. (illinois.edu)
Cancers3
- Cancers associés aux virus en Afrique. (who.int)
- Introduction: The immunity against cervical cancers is many unknown. (scirp.org)
- Most endometrial cancers are detected at an early stage, with the tumor confined to the uterine corpus in 75% of patients. (medscape.com)
Malignant1
- Various histological subtypes (including dysgerminoma, yolk sac neoplasm, choriocarcinoma and malignant teratoma) are reported. (cdc.gov)
Tumor5
- In our extended studies, we have directly examined the expressions of various inhibitory natural killer cell Receptors (iNKRs) on Tumor-infiltrating lymphocytes (TILs) derived from human Cervical cancer (CC) by triple-color flow cytometry with combination of different surface markers. (knowcancer.com)
- TVS is superior to CT and approaches MRI in its ability to depict endometrial carcinoma and to provide information regarding myometrial, cervical, and, perhaps, parametrial tumor invasion. (medscape.com)
- The primary cervical tumor contained large amounts of several distinct episomal forms as well as integrated HPV DNA. (omeka.net)
- Acidic and basic fibroblast growth factor expression levels in cervical cancer and their effects on tumor cell proliferation. (geneticsmr.com)
- It is a discrete, round, firm, often multiple uterine tumor composed of smooth muscle and connective tissue. (gafacom.website)
Lung1
- Risk factors associated with the leading causes of cancer death include tobacco use (lung, colorectal, stomach, and liver cancer), overweight/obesity and physical inactivity (breast and colorectal cancer), and infection (liver, stomach, and cervical cancer). (nih.gov)
Ovarian4
- Inainte papiloma humano laringe aparitia cancerului, celulele colului cervical se transforma, ovarian cancer jokes numit displazie, si devin celule anormale ale tesutului cervical. (etigararunway.ro)
- Vinil parazitii bad joke Adenom clasifică nemathelminthes hewan coloid icd-9, Metastatic cancer neck icd 10 Uterine cancer awareness month Breast Cancer Ovarian cancer jokes Month - cancer cerebral estadio 4 Afecțiuni tratate Quick Search: To find out which conditions can be treated in a minimally invasive way by interventional radiologists, click on the corresponding section below. (etigararunway.ro)
- Epithelial cystic tumors account for about 60% of all true ovarian neoplasms. (medscape.com)
- Mucinous epithelial tumors account for approximately 10-15% of all epithelial ovarian neoplasms. (medscape.com)
Abnormal1
- TVS is clinically established as the preferred technique for evaluation of endometrial disorders and is especially useful in the workup of abnormal uterine bleeding. (medscape.com)
Symptoms2
- Cervical cancer may not cause any symptoms at first. (medlineplus.gov)
- The two most common symptoms of uterine leiomyomas for which women seek treatment are AUB and pelvic pain or pressure. (gafacom.website)
Hysteroscopy1
- Hysterography or hysteroscopy can also confirm cervical or submucous myomas. (gafacom.website)
Prospective study1
- Serum antibodies and subsequent cervical neoplasms: a prospective study with 12 years of follow-up. (ox.ac.uk)
Antibodies4
- Antibodies to human papillomavirus and to other genital infectious agents and invasive cervical cancer risk. (ox.ac.uk)
- HPV 16-E7 and/or HPV 18-E7 antibodies were significantly related to cervical cancer risk (RR 1.9, 95% CI 1.2-3.2). (ox.ac.uk)
- Antibodies to HSV types 1 and 2, Chlamydia trachomatis, and to multiple infectious agents were associated with cervical cancer when seroprevalence rates in all cases and controls were compared, but when HPV-seropositive cases and controls were compared these associations were weaker and non-significant. (ox.ac.uk)
- After adjustment for smoking and other sexually transmitted diseases, antibodies to C. trachomatis showed the strongest association with cervical cancer (odds ratio = 5.0 (95% confidence interval 1.6-15.7)), but the numbers were too small for drawing conclusions as to the sexually transmitted diseases with which cervical cancer is most specifically associated. (ox.ac.uk)
Leiomyoma1
- A 5-cm uterine submucosal leiomyoma was detected and the patient underwent hysteroscopic myomectomy. (spandidos-publications.com)
Early Detection1
- National Breast and Cervical Cancer Early Detection Program (NBCCEDP), focusing on expanding access to cancer survivors within the course of treatment, when feasible, an antiviral prescription. (sirisampadagroup.com)