A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
Tumors or cancer of the URINARY BLADDER.
Pathological processes of the URINARY BLADDER.
Stones in the URINARY BLADDER; also known as vesical calculi, bladder stones, or cystoliths.
The epithelial lining of the URINARY TRACT.
A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.
Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.
Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.
Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. This is often associated with SPINAL CORD DISEASES, but may also be caused by BRAIN DISEASES or PERIPHERAL NERVE DISEASES.
A substituted carcinogenic nitrosamine.
Discharge of URINE, liquid waste processed by the KIDNEY, from the body.
The duct which coveys URINE from the pelvis of the KIDNEY through the URETERS, BLADDER, and URETHRA.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
Endoscopic examination, therapy or surgery of the urinary bladder.
Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.
Passage of a CATHETER into the URINARY BLADDER or kidney.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Inability to empty the URINARY BLADDER with voiding (URINATION).
Used for excision of the urinary bladder.
The mechanical laws of fluid dynamics as they apply to urine transport.
A species of the true toads, Bufonidae, becoming fairly common in the southern United States and almost pantropical. The secretions from the skin glands of this species are very toxic to animals.
The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.
Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.
Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
Presence of blood in the urine.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
An abnormal passage in the URINARY BLADDER or between the bladder and any surrounding organ.
Temporary or permanent diversion of the flow of urine through the ureter away from the URINARY BLADDER in the presence of a bladder disease or after cystectomy. There is a variety of techniques: direct anastomosis of ureter and bowel, cutaneous ureterostomy, ileal, jejunal or colon conduit, ureterosigmoidostomy, etc. (From Campbell's Urology, 6th ed, p2654)
A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
A birth defect in which the URINARY BLADDER is malformed and exposed, inside out, and protruded through the ABDOMINAL WALL. It is caused by closure defects involving the top front surface of the bladder, as well as the lower abdominal wall; SKIN; MUSCLES; and the pubic bone.
Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
An arsenical that has been used as a dermatologic agent and as an herbicide.
Flavoring agent and non-nutritive sweetener.
Partial or complete blockage in any part of the URETHRA that can lead to difficulty or inability to empty the URINARY BLADDER. It is characterized by an enlarged, often damaged, bladder with frequent urges to void.
A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
Surgical creation of an opening (stoma) in the URINARY BLADDER for drainage.
Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.
A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOOTH MUSCLES.
Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER.
Pathological processes of the URINARY TRACT in both males and females.
A uroplakin subtype that heterodimerizes with UROPLAKIN IB to form a component of the asymmetric unit membrane found in urothelial cells.
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Examination of urine by chemical, physical, or microscopic means. Routine urinalysis usually includes performing chemical screening tests, determining specific gravity, observing any unusual color or odor, screening for bacteriuria, and examining the sediment microscopically.
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
A uroplakin subtype that heterodimerizes with UROPLAKIN IA to form a component of the asymmetric unit membrane found in urothelial cells.
Surgery performed on the urinary tract or its parts in the male or female. For surgery of the male genitalia, UROLOGIC SURGICAL PROCEDURES, MALE is available.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
The combination of two or more different factors in the production of cancer.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.
The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.
A complex network of nerve fibers in the pelvic region. The hypogastric plexus distributes sympathetic fibers from the lumbar paravertebral ganglia and the aortic plexus, parasympathetic fibers from the pelvic nerve, and visceral afferents. The bilateral pelvic plexus is in its lateral extent.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.
Elements of limited time intervals, contributing to particular results or situations.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Use of electric potential or currents to elicit biological responses.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Structures which collect and store urine and are emptied by catheterization of a cutaneous stoma or internal diversion to the urethra. The reservoirs are surgically created during procedures for urinary diversion.
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist.
An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.
Involuntary discharge of URINE that is associated with an abrupt and strong desire to void. It is usually related to the involuntary contractions of the detrusor muscle of the bladder (detrusor hyperreflexia or detrusor instability).
Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.
Methods and procedures for the diagnosis of diseases or dysfunction of the urinary tract or its organs or demonstration of its physiological processes.
Radiography of any part of the urinary tract.
Abnormal enlargement or swelling of a KIDNEY due to dilation of the KIDNEY CALICES and the KIDNEY PELVIS. It is often associated with obstruction of the URETER or chronic kidney diseases that prevents normal drainage of urine into the URINARY BLADDER.
An embryonic structure originating from the ALLANTOIS. It is a canal connecting the fetal URINARY BLADDER and the UMBILICUS. It is normally converted into a fibrous cord postnatally. When the canal fails to be filled and remains open (patent urachus), urine leaks through the umbilicus.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.
A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.
The family of true toads belonging to the order Anura. The genera include Bufo, Ansonia, Nectophrynoides, and Atelopus.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
An abnormal passage in any part of the URINARY TRACT between itself or with other organs.
The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.
One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)
Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.
A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Cell surface proteins that bind PURINES with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized classes of purinergic receptors in mammals are the P1 receptors, which prefer ADENOSINE, and the P2 receptors, which prefer ATP or ADP.
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
A nonapeptide that contains the ring of OXYTOCIN and the side chain of ARG-VASOPRESSIN with the latter determining the specific recognition of hormone receptors. Vasotocin is the non-mammalian vasopressin-like hormone or antidiuretic hormone regulating water and salt metabolism.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.
Contractions of the abdominal muscles upon stimulation of the skin (superficial abdominal reflex) or tapping neighboring bony structures (deep abdominal reflex). The superficial reflex may be weak or absent, for example, after a stroke, a sign of upper (suprasegmental) motor neuron lesions. (Stedman, 25th ed & Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p1073)
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Painful URINATION. It is often associated with infections of the lower URINARY TRACT.
Tumors or cancer of the URINARY TRACT in either the male or the female.
The killing of animals for reasons of mercy, to control disease transmission or maintain the health of animal populations, or for experimental purposes (ANIMAL EXPERIMENTATION).
Compounds that bind to and activate ADRENERGIC BETA-3 RECEPTORS.
Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.
That phase of a muscle twitch during which a muscle returns to a resting position.
Organic chemicals which have two amino groups in an aliphatic chain.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
A non-hydrolyzed muscarinic agonist used as a research tool.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.
Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DISEASES.
The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
Properties, functions, and processes of the URINARY TRACT as a whole or of any of its parts.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.
A plant genus of the family DENNSTAEDTIACEAE. Members contain ptaquiloside, braxin A1, and braxin B. The name is similar to brake fern (PTERIS).
Neurons which send impulses peripherally to activate muscles or secretory cells.
An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
Surgical incision or puncture into a URINARY BLADDER. Cystotomy may be used to remove URINARY CALCULI, or to perform tissue repair and reconstruction.
A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.
An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE.
A subclass of purinergic P2 receptors that signal by means of a ligand-gated ion channel. They are comprised of three P2X subunits which can be identical (homotrimeric form) or dissimilar (heterotrimeric form).
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Cancer or tumors of the URETHRA. Benign epithelial tumors of the urethra usually consist of squamous and transitional cells. Primary urethral carcinomas are rare and typically of squamous cells. Urethral carcinoma is the only urological malignancy that is more common in females than in males.
Pathological processes involving the URETHRA.
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
A thin lining of closed cavities of the body, consisting of a single layer of squamous epithelial cells (MESOTHELIUM) resting on a thin layer of CONNECTIVE TISSUE, and covered with secreted clear fluid from blood and lymph vessels. Major serous membranes in the body include PERICARDIUM; PERITONEUM; and PLEURA.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Catheters inserted into the URINARY BLADDER or kidney for therapeutic or diagnostic purposes.
Drugs that bind to and activate cholinergic receptors.

Obstructive uropathy and hydronephrosis in male KK-Ay mice: a report of cases. (1/3541)

Uropathy associated with hydronephrosis was observed frequently in our male KK-Ay mouse colony during a long-term study of diabetes. The lesion occurred in 24 of the 31 KK-Ay male mice and accounted for the greatest number of spontaneous deaths among them. It was observed after 4 months of age and involved about hard plugs of altered seminal material resembling the seminal vesicle secretion. The plugs became impacted in the urethral bulb and the bladder. The penile anatomy, with its flexure, pressure on the urethra from the bulbocavernosus muscle, and the characteristic ability of the seminal fluid to easily coagulate to form the vaginal plug may have contributed to the lesion. Correlation between development of the uropathy and diabetes has not been established.  (+info)

Evidence for beta3-adrenoceptor subtypes in relaxation of the human urinary bladder detrusor: analysis by molecular biological and pharmacological methods. (2/3541)

The purpose of the present study was to confirm the presence of beta3-adrenoceptor subtype in the relaxation of human urinary bladder detrusor tissue by reverse transcription-polymerase chain reaction (PCR); direct sequencing of the PCR product, in situ hybridization; and isometric contraction. Using reverse transcription-PCR, the mRNAs of three receptor subtypes (beta1, beta2, and beta3) were expressed in the human urinary bladder detrusor tissue. Direct sequencing of the PCR product of the above beta3-adrenoceptor revealed no mutation in the amplified regions. In situ hybridization with digoxygenin-labeled oligonucleotide probe revealed the presence of the mRNA of beta3-adrenoceptor subtype in the smooth muscle of the urinary bladder. The relaxant effects of isoproterenol (a nonselective beta-adrenoceptor agonist); ZD7114, BRL37344, and CGP12177A (putative selective beta3-adrenoceptor agonists); and SR59230A (a putative selective beta3-adrenoceptor antagonist) were tested using an isometric contraction technique. Isoproterenol in either the presence or absence of both atenolol (a beta1-adrenoceptor-selective antagonist) and butoxamine (a beta2-adrenoceptor-selective antagonist) revealed a relaxant effect on the carbachol-induced contraction of the human urinary bladder detrusor. Both BRL37344 and CGP12177A also revealed relaxant effects on the human urinary bladder detrusor, but ZD7114 did not elicit any relaxation. These results suggest that beta3-adrenoceptor may have some role in urine storage in the human urinary bladder.  (+info)

Adrenoreceptors of the guinea-pig urinary bladder. (3/3541)

1 Adrenaline, noradrenaline and isoprenaline (5 mug/ml) did not affect the resting tone of the isolated urinary bladder of the guinea-pig. 2 The catecholamines (1-2 mug/ml) inhibited neuronally evoked contractions at various stimulation frequencies; the inhibition was maximum at 2 Hz and minimum at 50 Hz. Isoprenaline produced maximum inhibition. 3 Propranolol (0.5 mug/ml) completely blocked the catecholamine-induced inhibition at all the frequencies employed. The concentration-response curves of isoprenaline at 2, 10 and 50 Hz were characteristically shifted by propranolol (50 ng/ml). Phenoxybenzamine (0.2 mug/ml) was totally ineffective. 4 In some experiments adrenaline significantly raised the tone of the bladder exposed to propranolol; this effect could be blocked by phenoxybenzamine. 5 Acetylcholine-induced bladder contractions were inhibited by adrenaline (2 mug/ml); the inhibition was completely blocked by propranolol (0.5 mug/ml). 6 The results indicate the presence of an inhibitory beta-adrenoceptor and suggest the possibility of an excitatory alpha-adrenoceptor in guinea-pig urinary bladder.  (+info)

M2 receptors in genito-urinary smooth muscle pathology. (4/3541)

In vitro bladder contractions in response to cumulative carbachol doses were measured in the presence of selective muscarinic antagonists from rats which had their major pelvic ganglion bilaterally removed (denervation, DEN) or from rats in which the spinal cord was injured (SCI) via compression. DEN induced both hypertrophy (505+/-51 mg bladder weight) and a supersensitivity of the bladders to carbachol (EC50=0.7+/-0.1 uM). Some of the SCI rats regained the ability to void spontaneously (SPV). The bladders of these animals weighed 184+/-17 mg, significantly less than the bladders of non voiding rats (NV, 644+/-92 mg). The potency of carbachol was greater in bladder strips from NV SCI animals (EC50=0.54+/-0.1 uM) than either bladder strips from SPV SCI (EC50=0.93+/-0.3 microM), DEN or control (EC50=1.2+/-0.1 microM) animals. Antagonist affinities in control bladders for antagonism of carbachol induced contractions were consistent with M3 mediated contractions. Antagonist affinities in DEN bladders for 4-diphenlacetoxy-N-methylpiperidine methiodide (4-DAMP, 8.5) and para fluoro hexahydrosilodifenidol (p-F-HHSiD, 6.6); were consistent with M2 mediated contractions, although the methoctramine affinity (6.5) was consistent with M3 mediated contractions. p-F-HHSiD inhibited carbachol induced contraction with an affinity consistent with M2 receptors in bladders from NV SCI (pKb=6.4) animals and M3 receptors in bladders from SPV SCI animals (pKb=7.9). Subtype selective immunoprecipitation of muscarinic receptors revealed an increase in total and an increase in M2 receptor density with no change in M3 receptor density in bladders from DEN and NV SCI animals compared to normal or sham operated controls. M3 receptor density was lower in bladders from SPV SCI animals while the M2 receptor density was not different from control. This increase in M2 receptor density is consistent with the change in affinity of the antagonists for inhibition of carbachol induced contractions and may indicate that M2 receptors or a combination of M2 and M3 receptors directly mediate smooth muscle contraction in bladders from DEN and NV SCI rats.  (+info)

Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium. (5/3541)

Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiological methods whether EPO is toxic to mammalian urinary bladder epithelium. Results indicate that EPO, when added to the mucosal solution, increases apical membrane conductance of urinary bladder epithelium only when the apical membrane potential is cell interior negative. The EPO-induced conductance was concentration dependent, with a maximum conductance of 411 microseconds/cm2 and a Michaelis-Menten constant of 113 nM. The EPO-induced conductance was nonselective for K+ and Cl-. The conductance was partially reversed using voltage but not by removal of EPO from the bulk solution. Mucosal Ca2+ reversed the EPO-induced conductance by a mechanism involving reversible block of the conductance. Prolonged exposure (up to 1 h) to EPO was toxic to the urinary bladder epithelium, as indicated by an irreversible increase in transepithelial conductance. These results suggest that EPO is indeed toxic to urinary bladder epithelium via a mechanism that involves an increase in membrane permeability.  (+info)

Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. (6/3541)

IL-8 is a major human neutrophil chemoattractant at mucosal infection sites. This study examined the C-X-C chemokine response to mucosal infection, and, specifically, the role of macrophage inflammatory protein (MIP)-2, one of the mouse IL-8 equivalents, for neutrophil-epithelial interactions. Following intravesical Escherichia coli infection, several C-X-C chemokines were secreted into the urine, but only MIP-2 concentrations correlated to neutrophil numbers. Tissue quantitation demonstrated that kidney MIP-2 production was triggered by infection, and immunohistochemistry identified the kidney epithelium as a main source of MIP-2. Treatment with anti-MIP-2 Ab reduced the urine neutrophil numbers, but the mice had normal tissue neutrophil levels. By immunohistochemistry, the neutrophils were found in aggregates under the pelvic epithelium, but in control mice the neutrophils crossed the urothelium into the urine. The results demonstrate that different chemokines direct neutrophil migration from the bloodstream to the lamina propria and across the epithelium and that MIP-2 serves the latter function. These findings suggest that neutrophils cross epithelial cell barriers in a highly regulated manner in response to chemokines elaborated at this site. This is yet another mechanism that defines the mucosal compartment and differentiates the local from the systemic host response.  (+info)

Nosema notabilis (Microsporidia), its ultrastructure and effect on the myxosporean host Ortholinea polymorpha. (7/3541)

Nosema notabilis Kudo, 1939 produces chain-forming meronts with a dense cell coat in direct contact with the host cell cytoplasm. Cytoplasmic microtubules and membranaceous whorls could be observed in meront cytoplasm. Sporonts differ in that they have a thicker cell wall and more conspicuous endoplasmic reticulum (ER) cisternae. Sporoblasts have an externally ridged cell wall. Spores have an apically located anchoring disc, an isofilar polar tube with 6 to 9 turns and polyribosomal strands in the sporoplasm. Diplokarya occur in all stages. Heavily infected plasmodia of Ortholinea polymorpha (Davis, 1917) reveal marked pathological signs. The most prominent are reduction of surface projections and/or pinocytosis, inflated mitochondria with altered inner structures, affected vegetative nuclei, damage to generative cells and occurrence of various anomalous formations in the plasmodium cytoplasm. The damage may result in complete disintegration of the plasmodium. However, the development of the microsporidian is affected by a remarkably high percentage of teratological stages revealing membranaceous and tubular structures.  (+info)

Neurogenic plasma leakage in mouse airways. (8/3541)

1. This study sought to determine whether neurogenic inflammation occurs in the airways by examining the effects of capsaicin or substance P on microvascular plasma leakage in the trachea and lungs of male pathogen-free C57BL/6 mice. 2. Single bolus intravenous injections of capsaicin (0.5 and 1 micromol kg(-1), i.v.) or substance P (1, 10 and 37 nmol kg(-10, i.v.) failed to induce significant leakage in the trachea, assessed as extravasation of Evans blue dye, but did induce leakage in the urinary bladder and skin. 3. Pretreatment with captopril (2.5 mg kg(-1), i.v.), a selective inhibitor of angiotensin converting enzyme (ACE), either alone or in combination with phosphoramidon (2.5 mg kg(-1), i.v.), a selective inhibitor of neutral endopeptidase (NEP), increased baseline leakage of Evans blue in the absence of any exogenous inflammatory mediator. The increase was reversed by the bradykinin B2 receptor antagonist Hoe 140 (0.1 mg kg(-1), i.v.). 4. After pretreatment with phosphoramidon and captopril, capsaicin increased the Evans blue leakage above the baseline in the trachea, but not in the lung. This increase was reversed by the tachykinin (NK1) receptor antagonist SR 140333 (0.7 mg kg(-1), i.v.), but not by the NK2 receptor antagonist SR 48968 (1 mg kg(-1), i.v.). 5. Experiments using Monastral blue pigment as a tracer localized the leakage to postcapillary venules in the trachea and intrapulmonary bronchi, although the labelled vessels were less numerous in mice than in comparably treated rats. Blood vessels of the pulmonary circulation were not labelled. 6. We conclude that neurogenic inflammation can occur in airways of pathogen-free mice, but only after the inhibition of enzymes that normally degrade inflammatory peptides. Neurogenic inflammation does not involve the pulmonary microvasculature.  (+info)

QINGXIN, Liu et al. Apigenin inhibits cell migration through MAPK pathways in human bladder smooth muscle cells. Biocell [online]. 2011, vol.35, n.3, pp.71-79. ISSN 0327-9545.. Apigenin, a nonmutagenic flavonoid, has been shown to possess free radical scavenging activities, anticarcinogenic properties, antioxidant and anti-inflammatory effects. Recently, apigenin was reported to cause gastric relaxation in murine. To assess possible effects of apigenin on migration of bladder smooth muscle (SM) cell, we isolated SM cells from peri-cancer tissue of human bladder and established a cell model that was capable to overexpress transiently MEKK1 (MEK kinase 1). Results showed that overexpression of active human MEKK1 by adenoviruses infection induced migration of human bladder smooth muscle (hBSM) cells and phosphorylation of MAPKs, ERK, JNK and p38, which are the downstream molecules of MEKK1. Then, hBSM cell overexpressing MEKK1 were exposed to apigenin (50 μM). Our data indicated that apigenin ...
The effects of hypotonic solutions on intracellular Ca2+ were determined on primary cultures of human detrusor smooth muscle cells. In the presence of external Ca2+, changing from a solution containing 290 mosmol l-1 to one containing 240 mosmol l-1 (80% normal tonicity) activated a rise in intracellular Ca2+. If the exposure to 240 mosmol l-1 was followed by exposure to 150 mosmol l-1 (50% normal tonicity) a further increase in Ca2+ was noted. Exposure to hypotonic solutions which contained nominally zero Ca2+ also resulted in a rise in intracellular Ca2+, suggesting that mechanical perturbation of the surface membrane can mobilize Ca2+ directly from intracellular stores. Stimulation of cells with a brief exposure to agonist (histamine, 5 microM) in the nominal absence of external Ca2+ produced a release of Ca2+ from intracellular stores. Under these conditions the response to a subsequent hypotonic stimulation was small or absent. These observations suggest that hypotonic stress induces a mobilization
The uroepithelium lines the urinary bladder, urethra and the lower renal pelvis. It provides a tight blood-urine barrier that prevents the unregulated movement of solutes, ions and metabolites present in the urine. Apart from forming a robust barrier, a growing body of evidence supports the role of the uroepithelium as a sensory transducer that is sensitive to extracellular biochemical and mechanical stimuli. One of the mediators that is released from the uroepithelium and impacts bladder activity is adenosine. Adenosine is a well-known stress relieving hormone in other organ systems and the bladder lumen is a region of constant stress due to cyclical filling and voiding of urine, therefore I hypothesized that adenosine has an impact on urinary bladder function under stress. First I assessed the mechanism of adenosine turnover and how luminal adenosine affects bladder function. I report that adenosine is released from the mucosal and serosal surfaces of the uroepithelium when the tissue is ...
The aim of this study was to characterize endothelin receptor subtypes of the detrusor muscle of the human urinary bladder. The receptor subtypes mediating endothelin (ET)-1-induced activity in the human detrusor smooth muscles have been characterized using isometric contraction and reverse transcription-polymerase chain reaction (RT-PCR). ET-1 (a non-selective ET receptor agonist; 10-10 M to 10-6 M) exhibited concentration-dependent contractions in human urinary bladder with a plateau at concentrations above 3×10-7 M. Neither IRL1620 nor sarafotoxin S6c (both ETB-selective agonists; 10-10 M to 10-6 M) elicited contractile activity in the human urinary bladder detrusor smooth muscle. FR139317 (an ETA-selective antagonist; 10-7 M to 10-5 M) produced a marked shift to the right of the ET-1 concentration-response curve in human urinary bladder detrusor smooth muscle (from the Schild plot TpA2 = 7.96; slope = 0.95). In contrast, RES701-1 (an ETB-selective antagonist; 10-7 M to 10-5 M) had no effect ...
TY - JOUR. T1 - Normal reference values for bladder wall thickness on CT in a healthy population. AU - Fananapazir, Ghaneh. AU - Kitich, Aleksandar. AU - Lamba, Ramit. AU - Stewart, Susan L. AU - Corwin, Michael T. PY - 2018/2/1. Y1 - 2018/2/1. N2 - Purpose: To determine normal bladder wall thickness on CT in patients without bladder disease. Materials and methods: Four hundred and nineteen patients presenting for trauma with normal CTs of the abdomen and pelvis were included in our retrospective study. Bladder wall thickness was assessed, and bladder volume was measured using both the ellipsoid formula and an automated technique. Patient age, gender, and body mass index were recorded. Linear regression models were created to account for bladder volume, age, gender, and body mass index, and the multiple correlation coefficient with bladder wall thickness was computed. Bladder volume and bladder wall thickness were log-transformed to achieve approximate normality and homogeneity of variance. ...
Increased phasic activity in the bladder smooth muscle of animal models and patients with detrusor overactivity has been suggested to underlie the pathophysiology of overactive bladder. Potassium (K+) channels are key regulators of bladder smooth muscle tone and thus may play a role in this altered phasic activity. In this study the effects of K+ channel modulators on the phasic activity of bladder strips from the streptozotocin-induced diabetic rat model of bladder dysfunction were investigated. Bladder strips from rats 1 week following streptozotocin administration and age-matched controls were mounted in tissue baths at 37 °C and the effects of K+ channel modulators on resting basal tension or phasic activity induced by a low concentration of carbachol (0.5 μM) were investigated. Activation of BKCa channels by NS1619 had a minor inhibitory effect on carbachol-induced phasic activity of bladder strips from control and diabetic rats, and significantly inhibited amplitude only at 30 μM. Activation of
TY - JOUR. T1 - Spontaneous contractions of the pig urinary bladder. T2 - The effect of ATP-sensitive potassium channels and the role of the mucosa. AU - Akino, Hironobu. AU - Chapple, Christopher R.. AU - McKay, Neil G.. AU - Cross, Rebecca L.. AU - Murakami, Shigetaka. AU - Yokoyama, Osamu. AU - Chess-Williams, Russell. AU - Sellers, Donna J.. PY - 2008/11. Y1 - 2008/11. N2 - OBJECTIVE: To investigate the influence of the mucosa on the inhibitory effects of the ATP-sensitive potassium channel (KATP channel) opener, cromakalim, on the spontaneous contractions of pig bladder strips from the bladder dome and trigone. Little is known about the influence of the mucosa on spontaneous contractions and whether the nature of these contractions differs between the bladder dome and trigone. MATERIALS AND METHODS: Paired longitudinal strips of female pig bladders were isolated from the dome and trigone. The mucosa was removed from one strip per pair and tissues were set up in organ baths. Spontaneous ...
C57BL/6-GFP Mouse Bladder Epithelial Cells from Creative Bioarray are isolated from C57BL/6-GFP-Tg(CAG-EGFP)1Osb/J mouse bladder tissue of pathogen-free laboratory mice. C57BL/6-GFP Mouse Bladder Epithelial Cells are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarrays Culture Complete Growth Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x10^6cells per ml and is delivered frozen. Cells can be expanded for 3-7 passages at a split ratio of 1:2 under the cell culture conditions specified by Creative Bioarray. Repeated freezing and thawing of cells is not recommended ...
The urinary bladder is the organ that collects urine excreted by the kidneys before disposal by urination. The urinary bladder is a triangular, hollow and distensible (or elastic) organ that is located in the lower abdominal region. Urine enters the bladder via the ureters and exits via the urethra. Bladders occur throughout much of the animal kingdom, but they are very diverse in form and in some cases are not homologous with the urinary bladder in humans. The human urinary bladder is derived in embryo from the urogenital sinus and, it is initially continuous with the allantois. In males, the base of the bladder lies between the rectum and the pubic symphysis. It is superior to the prostate, and separated from the rectum by the rectovesical excavation. In females, the bladder sits inferior to the uterus and anterior to the vagina; thus, its maximum capacity is lower than in males. It is separated from the uterus by the vesicouterine excavation. In infants and young children, the urinary bladder ...
The urinary bladder is the organ that collects urine excreted by the kidneys before disposal by urination. The urinary bladder is a triangular, hollow and distensible (or elastic) organ that is located in the lower abdominal region. Urine enters the bladder via the ureters and exits via the urethra. Bladders occur throughout much of the animal kingdom, but they are very diverse in form and in some cases are not homologous with the urinary bladder in humans. The human urinary bladder is derived in embryo from the urogenital sinus and, it is initially continuous with the allantois. In males, the base of the bladder lies between the rectum and the pubic symphysis. It is superior to the prostate, and separated from the rectum by the rectovesical excavation. In females, the bladder sits inferior to the uterus and anterior to the vagina; thus, its maximum capacity is lower than in males. It is separated from the uterus by the vesicouterine excavation. In infants and young children, the urinary bladder ...
If these nerves are damaged by illness or injury, the muscles may not be able to tighten or relax at the right time. Neurogenic bowel is the loss of normal bowel function. This interferes with the normal ability to store and eliminate waste. The nerves of the cauda equina provide motor and sensory function to the legs and the bladder. This means that people are expected to have the strength to withhold voiding until a socially acceptable time. A device can be placed under your skin to deliver mild electrical pulses to the nerves that control bladder function. Some of these sacral nerves go to the rectum, the bladders detrusor muscle, levator ani muscle, and external sphincter muscles, controlling their activities. In turn, In turn, Bladder function - neurological control - Health Video: MedlinePlus Medical Encyclopedia s y . Areflexic bowel usually results from SCI that damages the lower end of the spinal cord or the nerve branches that go out to the bowel. The bladder is a hollow organ located ...
TY - JOUR. T1 - Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder. AU - Ajalloueian, Fatemeh. AU - Lemon, Greg. AU - Hilborn, Jöns. AU - Chronakis, Ioannis S.. AU - Fossum, Magdalena. PY - 2018. Y1 - 2018. N2 - The urinary bladder is a complex organ with the primary functions of storing urine under low and stable pressure and micturition. Many clinical conditions can cause poor bladder compliance, reduced capacity, and incontinence, requiring bladder augmentation or use of regenerative techniques and scaffolds. To replicate an organ that is under frequent mechanical loading and unloading, special attention towards fulfilling its biomechanical requirements is necessary. Several biological and synthetic scaffolds are available, with various characteristics that qualify them for use in bladder regeneration in vitro and in vivo, including in the treatment of clinical conditions. The biomechanical properties of the native bladder can be investigated using ...
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PURPOSE: To investigate whether delivering an increased radiation dose to the tumor-bearing region of the bladder alone would improve local disease control without increasing treatment toxicity. METHODS AND MATERIALS: A total of 149 patients with unifocal T2-T3N0M0 bladder carcinoma were randomized between whole bladder conformal radiotherapy (WBRT, 52.5 Gy in 20 fractions, n = 60) and partial bladder conformal RT (PBRT) to tumor alone with 1.5-cm margins within either 4 weeks (PBRT4, 57.5 Gy in 20 fractions, n = 44) or 3 weeks (PBRT3, 55 Gy in 16 fractions, n = 45). The response was assessed cystoscopically after 4 months. RESULTS: The 5-year overall and CFS rate was 58% and 47%, respectively, for the whole population. The CR rate was 75% for WBRT, 80% for PBRT4, and 71% for PBRT3 (p = 0.6), with a 5-year local control rate of 58%, 59%, and 34%, respectively (p = 0.18). Solitary new tumors arose within the bladder, outside the irradiated volume, in 6 (7%) of 89 patients who underwent PBRT. The ...
Synonyms for atonic urinary bladder in Free Thesaurus. Antonyms for atonic urinary bladder. 13 words related to urinary bladder: apparatus urogenitalis, genitourinary apparatus, genitourinary system, systema urogenitale, urinary apparatus.... What are synonyms for atonic urinary bladder?
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Study Objective: To determine the validity of bladder scan BV13000 in detection of bladder volume in immediate postpartum women. Methodology: A prospective cross sectional study conducted in Hospital Tengku Ampuan Afzan, Pahang from 1st September to 30 November 2010, A total of 193 women who had undergone Caesarean section were recruited on postpartum day 1. Prior to removal of Foleys catheter, their bladder volumes were first estimated by bladder scan BV13000. Immediately the bladder was then catheterized for the true bladder volume followed by 2D ultrasound bladder scanning to ensure that it was completely emptied. The data was analyzed using SPSS software version 18(SPSS Inc. Chigaco, Illinois). P value of less than 0.05 is considered as statistically significant. Resul : There were a total of 193 women recruited with the mean age of 28.84 years (SD 5.516) with mean BMI of 29.69( SD 5.69) kg/m2 and fundal height of 16cm (SD 2.382 ). The mean for time interval between bladder scan and ...
Intravesical electrical stimulation (IVES) has been used in treatment of patients with urinary bladder dysfunctions for more than four decades. While some investigators have reported excellent results others have observed less convincing effects or outright failures. The discrepancies may reflect differences in patient selection or stimulation procedure. A better theoretical understanding of the IVES working mechanism might help to improve the success rate of the treatment. The aims of the present study were to provide such information.. Experiments were performed on adult female cats and rats under /alpha/-chloralose anesthesia. IVES was delivered by a catheter electrode in the bladder. At proper intensity and frequency, IVES evoked reflex detrusor contractions that were abolished by bilateral rhizotomy of sacral dorsal roots. Stimulation parameters and response characteristics revealed that bladder mechanoreceptor A/delta/ afferents were activated by the IVES, the same afferents that drive the ...
Zhou, Y.,Tan, C.K.,Ling, E.A. (1997). Distribution of NADPH-diaphorase and nitric oxide synthase-containing neurons in the intramural ganglia of guinea pig urinary bladder. Journal of Anatomy 190 (1) : 135-145. [email protected] Repository. https://doi.org/10.1017/S0021878296001549 ...
Spinal cord injury (SCI) disconnects supraspinal micturition centers from the lower urinary tract resulting in immediate and long-term changes in bladder structure and function. While cervical and high thoracic SCI have a greater range of systemic effects, clinical data suggest that those with lower (suprasacral) injuries develop poorer bladder outcomes. Here we assess the impact of SCI level on acute changes in bladder activity. We used two SCI models, T3 and L2 complete transections in male Wistar rats, and compared bladder pressure fluctuations to those of naïve and bladder-denervated animals. By 2 days after L2 transection, but not T3 transection or bladder denervation, small amplitude rhythmic contractions (1 mmHg, 0.06 Hz) were present at low intravesical pressures (
Looking for irritable urinary bladder? Find out information about irritable urinary bladder. a distensible membranous sac in which the urine excreted from the kidneys is stored the organ in which urine accumulates before being excreted from the body... Explanation of irritable urinary bladder
TY - JOUR. T1 - The effect of adriamycin (ADR) on a human bladder cell line (MGH-U1) grown as a monolayer, as spheroids and in immune-deprived mice. AU - Erlichman, C.. AU - Vidgen, D.. AU - Tannock, I. F.. PY - 1982/1/1. Y1 - 1982/1/1. UR - http://www.scopus.com/inward/record.url?scp=0020063457&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0020063457&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0020063457. VL - Vol. 23. JO - Proceedings of the American Association for Cancer Research. JF - Proceedings of the American Association for Cancer Research. ER - ...
The amount of urine left in the urinary bladder after voiding, depends on the age and gender of the patient, Some medications and medical problems such as diabetes or multiple sclerosis may affect how well the bladder empties. To some extent, the amount of urine present in the bladder prior to urination also affects how much is left at the end of urination.. Normal bladder capacity is around 500 ml but varies. If someone has 150 ml left in the bladder, that means that 30% of the bladder is filled already right after they have urinated. As a result, the time they have to fill the bladder (the time until they get the urge to pee again) is shorter by 30%. If bladder capacity is also small, for example only 300 ml, and post-void residual is 150 ml, then the bladder empties only half-way, and this may be one of the reasons people with incomplete bladder emptying have a frequent urge to urinate.. Younger patients should not have any urine left in the bladder after urination or a minimal amount. In ...
Dive into the research topics of Prediction of radiosensitivity in human bladder cell lines using nuclear chromatin phenotype.. Together they form a unique fingerprint. ...
Sphincter muscle of urinary bladder definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
Purpose Detrusor overactivity contributes to bothersome constellation of lower urinary tract symptoms (LUTS) in men and women as they age. However, the underlying mechanisms of non-obstructive detrusor overactivity and LUTS remain largely unknown. Growing evidence suggests that ischemia may be an independent factor in the development of non-obstructive bladder dysfunction. Our goal was to determine the effects of ischemia on detrusor function and voiding behavior and define redox-mediated cellular stress and cell survival signaling in the ischemic bladder. Materials and methods Male Sprague Dawley rats were randomly divided into treatment (n=8) and control (n=8) groups. In the treatment group, iliac artery atherosclerosis and chronic bladder ischemia were induced. At 8 weeks after bladder ischemia, voiding patterns were examined in metabolic cages, cystometrograms were recorded in conscious animals, and then bladder blood flow was measured under general anesthesia. Bladder tissues were processed ...
Male urinary bladder inspection - Circumcision - Wikipedia, the free encyclopedia. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
AIMS: The functional integration of the smooth muscle of enterocystoplasties into the detrusor muscle was investigated in an awake-rat cystometry model and in vitro.. METHODS: The upper fourth of the bladder was removed, and a detubularized appendiceal segment (7 x 7 mm), with preserved vasculature, was incorporated into the bladder. After 1 or 3 months, a catheter was fixed to the top of the bladders. After a 3-day recovery, cystometries were performed. In separate experiments, agonist and nerve-induced responses were evaluated on isolated bladder strips.. RESULTS: Cystometries revealed reduced basal pressure and micturition pressure in enterocystoplasty (ECP) bladders. Bladder capacity and micturition volume were increased. Threshold pressure (pressure immediately before micturition) was significantly lower at 1 month, but not at 3 months. Bladder compliance was significantly higher in the operated at 1 month but not at 3 months. Threshold tension did not differ between control and ...
BALB/c Mouse Bladder Microvascular Endothelial Cells from Creative Bioarray are isolated from bladder tissue of pathogen-free laboratory mice. BALB/c Mouse Bladder Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarray Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and are delivered frozen. The method we use to isolate endothelial cells was developed based on a combination of established and our proprietary methods. These cells are pre-coated with PECAM-1 antibody, following the application of magnetic pre-coated with secondary antibody ...
Question - Diabetes, stroke, full bladder. Treatment for bladder fullness, advise?. Ask a Doctor about diagnosis, treatment and medication for Stroke, Ask a Urologist
Squamous cell carcinoma of the urinary bladder occurs after metaplasia of the urinary bladder epithelium from transitional cell to squamous cell. It can occurs in settings of schistosomaisis, chronic irritation by stones, and chronic infection.
Bladder overdistension has been found to cause transitional morphological changes in innervation which correlate with changes in micturition and bladder contractility. We investigated the influence of overdistension on bladder wall morphology using histological and enzyme histochemical methods. Overdistension was induced in female rats for 3 h by forced diuresis and balloon obstruction of the bladder neck. Oedema was seen beneath the mucosa at 12 h, with hyperemia and haemorrhages. The urothelium was mostly intact, although enzymes leaked out of the epithelial cells. The changes were increased at 24 h. The urothelium also showed some disruptions and degenerative vacuolization. The oedema reached its maximum at 48 h, and large numbers of inflammatory cells were also seen. The urothelium was disruptured in many places and vacuolated, but the subendothelial capillaries remained normal. Damage to some muscle cells was seen. After 7 days the oedema had disappeared and the urothelium was continuous. Enlarged
The complex model of the lower part of the urinary consists of the detrusor smooth muscle cell model and the detailed 1D model of the urethra flow. In future this model will allow to simulate the influence of different drugs and mechanical obstructions in the bladder neck and urethra. A general muscle model involving the calcium dynamics in the smooth muscle cell and the growth and remodelling theory will be shortly introduced. The main part is devoted to the development of a simple bladder model and the detrusor contraction during voiding together with the detailed model of the urethra flow ...
According to prevailing assumptions, UPEC strains are strictly extracellular pathogens. In this study, however, we provide evidence that host cell invasion enhances the ability of UPEC to successfully infect the bladder epithelium. Upon making contact with superficial epithelial cells in the bladder lumen, type 1-piliated UPEC induces a cascade of signaling events leading to bacterial internalization (27, 29). Following internalization UPEC is able to replicate, resulting in the formation of large collections of intracellular bacteria, which due to their appearance we have termed bacterial factories. UPEC strains were also shown to have the capacity to flux out of bladder epithelial cells, a process that may allow bacteria to escape from host superficial cells that are induced to exfoliate in response to infection. Bacteria exiting dying host cells are often filamentous, enabling them to maintain contact with the bladder epithelium as they leave one host cell and interact with neighboring and ...
Eviprostat is a popular phytotherapeutic agent for the treatment of lower urinary tract symptoms (LUTS). At present, the signaling mechanisms underlying its therapeutic effects are still poorly understood. Given that cAMP has been reported to suppress cell hyperplasia and hypertrophy in various pathological situations, we asked whether the effect of Eviprostat could be ascribed to the activation of the cAMP signaling pathway. In the study, exposure of cAMP response element (CRE)-secreted alkaline phosphatase (SEAP) (CRE-SEAP)-reporter cells to Eviprostat elevated SEAP secretion, which was associated with an increased phosphorylation of vasodilator-stimulated phosphoprotein (VASP) and cAMP-response element-binding protein (CREB), as well as enhanced expression of CRE-regulated protein connexin43, indicating an activation of the cAMP signaling pathway. Consistent with these observations, Eviprostat-induced expression of Cx43 was abolished in the presence of adenylyl cyclase inhibitor SQ22536 or PKA
Do you suffer from inflammation of the urinary bladder? Magnetic therapy can help you. Find out why physicians recommend magnetic therapy for inflammation of the urinary bladder.
Urinary bladder matrix, a skin substitute material made from porcine bladder, can be used successfully in periorbital reconstructive procedures, Ophthalmology Times reports.
functional abnormality (such as a very abnormal heart beat or mental. although there is still scientific and economic controversy about our conclusion, we would argue that, at a minimum, there is an ethical obligation to present the option of an 18-22-week routine obstetric ultrasound examination in clinical centers in which quality ultrasound is available. try to date the pregnancy, exclude twins and detect any fetal. important large scale studies emerged to address the issue: the radius study (routine antenatal diagnostic imaging with ultrasound) with a cohort of 15,000 low-risk pregnancies in the united states in 1993 and the eurofetus study in europe in 1997 in which 200,000 low-risk pregnant women in 60 hospitals had obstetric ultrasound examinations performed in centers proficient in prenatal diagnosis. there were definitely no boy parts down there, and she started. sonogram and told that nothing is wrong other than the. the sonographer will put some gel on your tummy and move a small ...
Cystometry is a diagnostic procedure used to identify problems with the filling and emptying of the urinary bladder. This test measures the amount of volume or urine in the bladder compared with the bladder pressure and the persons perception of bladder fullness. Cystometry provides information about the muscle function, mechanics, and nerve response of the bladder and urinary tract.. A normally functioning bladder sends messages to the brain via nerve pathways when it needs emptying. The spinal cord then transmits a message to the bladder to contract and begin the reflex of urinating. A person can override this reflex voluntarily by holding his or her urine.. Some medical conditions may interfere with the muscular function or nerve pathways between the bladder and the brain. These conditions may lead to urinary incontinence (loss of bladder control) or urinary obstruction. Cystometry may be indicated to determine the source of such problems. It is often done together with Uroflowmetry, which ...
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Nowadays, a role of the whole range of factors of hyperactive bladder development is being discussed.. They are as follows:. - Sex and Age Hyperactive bladder risk increases with the age. The critical age is above 60 - elderly people have maximal probability to get affected by hyperactive bladder. For men, this risk is explained by prostatic hyperplasia the symptoms of which are present in almost all men above 60. Nevertheless, absence of hyperplasia doesnt exclude occurrence of age-related changes of bladder which are nearly identical in both, men and women.. Hyperactive bladder development in elderly people is usually an accompanying disease with neurogenic and vascular component, such as diabetes, cerebrovascular pathology, atherosclerosis of huge vessels, etc.. - Genetic Factor. It is difficult to detect this factor in hyperactive bladder syndrome. For unbiased estimate of heredity role, it is essential to examine affined individuals under conditions of similar environment and lifestyle. ...
Bladder regeneration based on minced bladder mucosa in vivo expansion is an alternative to in vitro culturing of urothelial cells. Here, we present the design of a hybrid, electrospun poly(lactic-co-glycolide) (PLGA) - plastically compressed (PC) collagen scaffold that could allow in vivo bladder mucosa expansion. Optimisation of electrospinning was performed in order to obtain increased pore sizes and porosity to consolidate the construct and to support neovascularisation and tissue ingrowth. Tensile tests showed an increase in average tensile strength from 0.6 MPa for PC collagen to 3.57 MPa for the hybrid construct. The optimised PLGA support scaffold was placed between two collagen gels, and the minced tissue was distributed either on top or both on top and inside the construct prior to PC; this was then cultured for up to four weeks. Morphology, histology and SEM demonstrated that the construct maintained its integrity throughout cell culture. Cells from minced tissue migrated, expanded and ...
Intravesical Adriamycin treatment was given to 22 patients with carcinoma in situ of the urinary bladder. The treatment schedule consisted of monthly Adriamycin instillations in a dose related to bladder capacity. Endoscopic inspection with multiple bladder biopsies and cytoanalysis of urine was performed after every third instillation. In two patients there was lasting disappearance of the carcinoma in situ. Another 10 patients possibly had a beneficial effect of the treatment. The remaining 10 patients showed persistent malignancy and in 6 of these, progression of carcinoma in situ during Adriamycin treatment necessitated cystectomy or radiotherapy. The histologic and cytologic findings showed distinct variability in most patients, with atypia or even absence of malignant cells often followed by recurrence. Adriamycin was discontinued in four cases because of severe cystitis, and in one case because of an anaphylactoid reaction following instillation of the drug.
Looking for bladder cell? Find out information about bladder cell. Any of the large vacuolated cells in the outer layers of the tunic in some tunicates Explanation of bladder cell
Regions of tissue having reduced electrical propagation are created in a bladder to affect its electrical or mechanical properties. To create these tissue regions, a tubular device is advanced through the urethra leading to the interior of the bladder, a distal expandable structure of the device is expanded to contact the inner wall of the bladder, and electrodes or other active energy delivery elements of the device are activated to deliver ablation energy. The electrodes or other active energy delivery elements are disposed over the expandable structure which is shaped to conform to the interior of the bladder. The inner wall of the organ is ablated in a predetermined pattern. The same or other electrodes disposed over the expandable structure can used to electrically map the bladder. This map of electrical activity can be used to create the predetermined pattern.
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TY - JOUR. T1 - Transforming growth factor-β1 mediates migration in cultured human control and exstrophy bladder smooth muscle cells. AU - Suson, Kristina D.. AU - Stec, Andrew A.. AU - Gearhart, John Phillip. AU - Shimoda, Larissa. PY - 2012/10. Y1 - 2012/10. N2 - Purpose: Transforming growth factor-β1 regulates extracellular matrix composition, and impacts function and proliferation in multiple cell types, including bladder smooth muscle cells. In this study we evaluated the response to transforming growth factor-β1 in cultured exstrophy and control bladder smooth muscle cells. Materials and Methods: Primary bladder smooth muscle cell cultures were established from patients with bladder exstrophy or vesicoureteral reflux. Smooth muscle specific α-actin and heavy chain myosin expression was determined using immunohistochemistry. Cell migration, intracellular calcium concentration and proliferation were determined after incubation for 24 to 48 hours in basal media, with or without ...
Tobacco smoking is a major risk factor for human cancers including urinary bladder carcinoma. In a previous study, nicotine enhanced rat urinary bladder carcinogenesis in a two-stage carcinogenesis model. Nicotine also induced cytotoxicity in the bladder urothelium in a short-term study. In the present study, male rats were treated with nicotine (40 ppm) in drinking water co-administered with the NADPH oxidase inhibitor, apocynin (0, 250 or 750 mg/kg) in diet for 4 weeks. The apocynin treatment induced no clinical toxic effects. Reduction of reactive oxygen species (ROS) by apocynin was confirmed by immunohistochemistry of 8-OHdG in the bladder urothelium. Incidences of simple hyperplasia, cell proliferation and apoptosis were reduced by apocynin treatment in the bladder urothelium. However, despite reduction of cell proliferation (labeling index), apocynin did not affect the incidence of simple hyperplasia, apoptosis, or ROS generation in the kidney pelvis urothelium, in addition to 8-OHdG ...
The urinary bladder sits in a unique position inferior to the peritoneum, a membrane that lines most of the abdominopelvic cavity. Due to its position, the outermost layer of the superior urinary bladder is made of serous membrane continuous with the peritoneum. Serous membrane provides protection to the bladder from friction between organs in the abdominopelvic cavity. The surface of the lateral and inferior sides of the urinary bladder forms a layer of loose connective tissue known as the adventitia. The adventitia loosely connects the urinary bladder to the surrounding tissues of the pelvis.. The urinary bladder functions as a storage vessel for urine to delay the frequency of urination. It is one of the most elastic organs of the body and is able to increase its volume greatly to accommodate between 600 to 800 ml of urine at maximum capacity. Transitional epithelium, elastic fibers, and visceral muscle tissue in the walls of the urinary bladder contribute to its distensibility and ...
TY - JOUR. T1 - Superimposed histologic and genetic mapping of chromosome 17 alterations in human urinary bladder neoplasia. AU - Chaturvedi, Vijaya. AU - Li, Li. AU - Hodges, Sherie. AU - Johnston, Dennis. AU - Ro, Jae Y.. AU - Logothetis, Christopher. AU - Von Eschenbach, Andrew C.. AU - Batsakis, John G.. AU - Czerniak, Bogdan. PY - 1997. Y1 - 1997. N2 - Multistep alterations of chromosome 17 in the progression of human urinary bladder neoplasia were studied by superimposed histologic and genetic mapping. The p53 gene was included in the analysis as a model tumor suppressor gene that is frequently involved in urothelial carcinogenesis. The strategy provided a systematic approach to the study of multistep genomic alterations that occur as neoplasia progresses from precursor intraurothelial conditions to invasive cancer. This was accomplished by sampling the entire mucosa of the organ and displaying microscopically identified invasive cancer and precursor conditions in the form of a histologic ...
Purpose Type 3 muscarinic receptors, which are present in the bladder wall, are important for bladder function. However, their role in the context of the urothelium is not well defined. Understanding the role of type 3 muscarinic receptors has been limited by the lack of specific type 3 muscarinic receptor antibodies. Thus, we identified a specific type 3 muscarinic receptor antibody and investigated the site of type 3 muscarinic receptors in sham operated and obstructed guinea pig bladders. Materials and Methods The specificity of 4 commercially available type 3 muscarinic receptor antibodies was determined. Immunohistochemistry was then done in bladder tissue from sham operated and obstructed guinea pig bladders. Results One of the 4 antibodies examined had the needed specificity in terms of blocking peptide and Western blot characterization. Using this antibody type 3 muscarinic receptor immunoreactivity was associated with muscle cells, nerves and interstitial cells. Four types of ...
The urinary symptoms created by a neurogenic bladder depend on the cause or abnormality that has caused the problem. They often include urinary incontinence as well as frequent urination, an urgent sensation of urination, waking up at night to urinate (nocturia), inability to empty the bladder fully or an inability to urinate at all (urinary retention).Common symptoms described as overactive bladder can also be due to a neurogenic bladder. Symptoms can include urinating frequently in small amounts, sensation of not being able to empty all urine from the bladder, and loss of bladder control. Overactive bladder may also be present in the absence of a defined neurological disease or disorder (idiopathic overactive bladder.) Other symptoms can also be attributed to an underactive bladder, where the bladder cannot squeeze hard enough to empty completely, resulting in sensation of a full bladder that may be associated with urine leakage, inability to tell when the bladder is full, difficulty starting to
Looking for online definition of cancer of urinary bladder in the Medical Dictionary? cancer of urinary bladder explanation free. What is cancer of urinary bladder? Meaning of cancer of urinary bladder medical term. What does cancer of urinary bladder mean?
TY - JOUR. T1 - Effects of isolectin B4-conjugated saporin, a targeting cytotoxin, on bladder overactivity induced by bladder irritation. AU - Nishiguchi, Jun. AU - Sasaki, Katsumi. AU - Seki, Satoshi. AU - Chancellor, Michael B.. AU - Erickson, Kristin A.. AU - De Groat, William C.. AU - Kumon, Hiromi. AU - Yoshimura, Naoki. PY - 2004/7. Y1 - 2004/7. N2 - In order to clarify the functional role of the isolectin B4 (IB4)-binding afferent pathway in the micturition reflex, we investigated the effects on bladder activity of intrathecal application of the IB4-saporin conjugate, a targeting cytotoxin that destroys neurons binding IB4. In rats, IB4-saporin (2.5 μm) or vehicle was administered through an intrathecal catheter implanted at the level of the L6-S1 spinal cord. Three weeks after IB4-saporin administration, cystometry in conscious animals revealed a reduction in bladder overactive responses induced by intravesical capsaicin or ATP infusion without affecting normal voiding function. In ...
Arachidonic metabolites, more specifically PGs, are released from the bladder into the general circulation in response to distension (79-81). It was found that PGs in the bladder wall originate from both the urothelial and muscle layers (79, 80). The exact role of this endogenous PG is not known, but it is well documented that exogenous PG alters bladder motor activity in vitro and in vivo and that it can also influence the micturition reflex in humans, (82-84) rats, (85) guinea pigs, (86) rabbits (87) and monkeys (88). The main PGs synthesized in the bladder are PGE2 (79-81) and PGI2 (89). PGs are locally synthesized in the bladder muscle and mucosa. This synthesis is initiated by stretch of the detrusor muscle, bladder nerve stimulation, bladder mucosa damage and inflammation mediators. The effects of PGs in the bladder have been studied in numerous studies. These studies have shown that bladder infusion with PGE2 enhances the micturition reflex and that urine levels of PGE2 are increased in ...
Postnatal response of the gall bladder to feeding was studied in 28 preterm infants (gestational age 24-37 weeks) by ultrasonography immediately before feeding and one hour after feeding. Nineteen of the infants were studied once during the first week of life, and nine infants were studied weekly from a postconceptional age of 27-31 until a postprandial gall bladder contraction was seen. A contraction index was calculated as a percentage decrement of the surface area of the gall bladder from its initial value. All preterm infants of more than 33 weeks gestation showed a gall bladder response to feeding with a contraction index of at least 50%. Very preterm infants (gestational age 27-32 weeks) showed no postprandial gall bladder contraction or the contraction index was under 50%. In a follow up study of nine very preterm infants, the contraction index exceeded 50% at a postconceptional age of 29 to 32 weeks. One infant with prolonged feeding problems had no postprandial gall bladder response ...
University of Iowa News. March 25, 2005 UI Study Seeks Adults With Urinary Frequency, Painful Bladder Problems. Men and women age 18 and older with certain urinary frequency and bladder problems are invited to participate in a University of Iowa research study on interstitial cystitis and painful bladder syndrome.. The study will compare the safety and effectiveness of an investigational medication to placebo (inactive substance) in reducing symptoms. Interstitial cystitis is a chronic, painful inflammatory condition of the bladder wall. An estimated 10 million people in the United States are affected by interstitial cystitis and painful bladder syndrome.. People with increased daytime and nighttime urinary frequency who have never sought treatment are eligible to participate. Individuals also eligible to participate are people who have not yet received treatment for lower abdominal or pelvic pain associated with a full bladder but who do not have a urinary tract infection.. Women who are ...
The urinary bladder is a temporary storage reservoir for urine. It is located in the pelvic cavity, posterior to the symphysis pubis, and below the parietal peritoneum. The size and shape of the urinary bladder varies with the amount of urine it contains and with pressure it receives from surrounding organs.. The inner lining of the urinary bladder is a mucous membrane of transitional epithelium that is continuous with that in the ureters. When the bladder is empty, the mucosa has numerous folds called rugae. The rugae and transitional epithelium allow the bladder to expand as it fills.. The second layer in the walls is the submucosa that supports the mucous membrane. It is composed of connective tissue with elastic fibers.. The next layer is the muscularis, which is composed of smooth muscle. The smooth muscle fibers are interwoven in all directions and collectively these are called the detrusor muscle. Contraction of this muscle expels urine from the bladder. On the superior surface, the outer ...
The concentration-effect relationships of carbachol were studied for three different responses of detrusor muscle of rabbit urinary bladder: the mechanical response, the increase of 45Ca uptake and the displacement of [3H]quinuclidinyl benzilate (QNB) from muscarinic receptors. The EC50 for carbachol in production of contractile responses of the detrusor muscle was observed to be 0.27 microM. The 45Ca uptake by detrusor muscle strips was studied by the lanthanum-residual wash out method. Carbachol increased 45Ca uptake with an EC50 of 12.7 microM. [3H]QNB binding was performed on homogenates of rabbit bladder detrusor muscle. By Scatchard analysis, the receptor density was found to be 47.2 fmol/mg of protein and the KD 0.074 nM. The contractile responses, the 45Ca uptake and the specific [3H]QNB binding were all blocked by atropine and so are taken to represent muscarinic receptor-mediated phenomena. Carbachol displacement of [3H]QNB yielded an EC50 of 135 microM and a Kl of 42 microM. It is ...
In the current study all of the patients underwent sigmoid cystoplasties for 1-12 months (mean, 4.6 ± 1.2 months) because of a neurogenic bladder secondary to incomplete spinal cord injuries, meningoceles, or spina bifida. After recovering from surgery, the patients were asked to empty their bladders by CIC; however, the mean bladder capacity was only 280.5 ± 11.7 ml at early follow-up post-operatively based on urodynamic evaluation, which was unsatisfactory for those subjects who had undergone cystoplasty. In our previous research [1], we showed that the most common problem within 6 months post-operatively was incontinence, which might have resulted from the weakened function of the sphincter post-operatively. The presence of an indwelling urethral catheter for a long period could contribute to sphincter weakness because the maximal urethral pressure at rest was significantly decreased during the 6-month follow-up examination compared with the pre-operative pressure. Automatic contraction of ...
Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction are attenuated with the NLRP3 inhibitor glyburide.
Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of the limitations of in vitro experiments on isolated human detrusor included inability to evaluate in vivo effects of TREK-1 on voiding function, as the channel is also expressed in the nervous system, and may modulate micturition via neural pathways. Therefore, in the present study, we aimed to assess the role of TREK-1 channel in bladder function and voiding patterns in vivo by using TREK-1 knockout (KO) mice. Adult C57BL/6 J wild-type (WT, N = 32) and TREK-1 KO (N = 33) mice were used in this study. The overall phenotype and bladder function were evaluated by gene and protein expression of TREK-1 channel, in vitro contractile experiments using detrusor strips in response to stretch and pharmacological stimuli, and cystometry in unanesthetized animals. TREK-1 KO animals had an elevated basal muscle tone
Bladder Strength is an advanced combination of ingredients that work together to support normal bladder function and bladder health. It is also recommended for spayed and senior pets to help maintain bladder control. Pumpkin Seed Powder has been used for prostate and bladder health and is beneficial to urinary tract health due to its cleansing action. It also strengthens bladder muscle and supports bladder emptying. Rehmannia glutinosa is a Chinese herb that supports renal function, and healthy levels of estradiol in females and testosterone in males. Wild Yam provides phytoestrogens and relaxes urinary tract muscles. Soy Protein Extract contains isoflavones that provide phytoestrogens to help maintain normal bladder muscle tone that is lost after spaying or due to aging because of lower estrogen levels. Corn Silk Powder contains polysaccharides and mucilage that can help support urinary tract comfort by fortifying mucosal GAG layers. Saw Palmetto Extract helps support normal bladder control and
Bladder irrigation procedure - ACI UROLOGY NETWORK NURSING- BLADDER IRRIGATION. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
Bladder Infection home cures: Chronic Bladder Infections In Women. Bladder Infection, Bladder infection: Symptoms, treatment and prevention.
article{355431f8-a828-40f5-aa88-02a4363356c0, abstract = {,p,Objective: To describe the clinical and ultrasound characteristics of urinary bladder malignancies diagnosed on transvaginal ultrasound in women presenting with suspected gynecological problems. Methods: This was a multicenter retrospective study of women with a histological diagnosis of urinary bladder malignancy that was suspected on transvaginal ultrasound examination. The cases were collected from three centers that specialize in the use of pelvic ultrasound and had been examined between January 2007 and October 2018. Clinical data were obtained from the computer databases and all tumor images were assessed by two of the authors (D.J. and J.K.) to identify characteristic sonographic patterns. We compared the characteristics of tumors between women presenting with symptoms suspicious of urinary bladder malignancy and those without such symptoms. Results: Thirty women with a confirmed diagnosis of urinary bladder malignancy on ...
TY - JOUR. T1 - De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis. AU - Thorson, Willa. AU - Diaz-Horta, Oscar. AU - Foster, Joseph. AU - Spiliopoulos, Michail. AU - Quintero, Ruben A.. AU - Farooq, Amjad. AU - Blanton, Susan. AU - Tekin, Mustafa. PY - 2014/6. Y1 - 2014/6. N2 - Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is characterized by prenatal-onset distended urinary bladder with functional intestinal obstruction, requiring extensive surgical intervention for survival. While it is believed to be an autosomal recessive disorder, most cases are sporadic. Through whole-exome sequencing in a child with MMIHS, we identified a de novo mutation, p.R178L, in the gene encoding the smooth muscle gamma-2 actin, ACTG2. We subsequently detected another de novo ACTG2 mutation, p.R178C, in an additional child with MMIHS. Actg2 transcripts were primarily found in murine urinary bladder and intestinal tissues. Structural analysis ...
Aspects of the relationships between cellular composition and transepithelial sodium transport across toad urinary bladder are reviewed. Changes in cellular sodium produced by amiloride, vasopressin,
Patients with spina bifida and a neurogenic bladder have traditionally been managed with clean intermittent catheterization and pharmacotherapy in order to treat abnormal bladder wall dynamics, protect the upper urinary tract from damage, and achieve urinary continence. However, some patients will fail this therapy and require surgical reconstruction in the form of bladder augmentation surgery using reconfigured intestine or stomach to increase the bladder capacity while reducing the internal storage pressure. Despite functional success of bladder augmentation in achieving a low pressure reservoir, there are several associated complications of this operation and patients do not have the ability to volitionally void. For these reasons, alternative treatments have been sought. Two exciting alternative approaches that are currently being investigated are tissue engineering and neuromodulation. Tissue engineering aims to create new bladder tissue for replacement purposes with both seeded and ...
This study could be criticized because heart rate was uncontrolled by cardiac pacing and the rate-pressure product was not held constant during the study. Although the patients were not paced during bladder distention, the degrees of changes in the rate-pressure product between the two groups were similar. Thus, the changes in the rate-pressure product could not be a major factor of vasoconstriction during bladder distention.. Another limitation of the present study was a lack of normal control data for ethical reasons. The invasive nature of the study made it impractical to have a normal control group. Instead, each patient serves as his or her own control.. The third limitation of the present study was the poor sensitivity of the surface ECG to detect myocardial ischemic during bladder distention. Sutton et al. (34) reported on the electrical focus, causing the ST segment changes to be a localized area of myocardium, and therefore may not be apparent on the leads of a surface ECG. Besides, the ...
Jan. 16, 2007 [Note to Editors: This release about a UI clinical study was last distributed Oct. 16, 2006. Participants still are welcome to participate in the study.]. UI Study Seeks Adults With Urinary Frequency, Painful Bladder Problems. Men and women age 18 and older with certain urinary frequency and bladder problems are invited to participate in a University of Iowa research study on interstitial cystitis and painful bladder syndrome.. The study will compare the safety and effectiveness of an investigational medication to placebo (inactive substance) in reducing symptoms. Interstitial cystitis is a chronic, painful inflammatory condition of the bladder wall. An estimated 10 million people in the United States are affected by interstitial cystitis and painful bladder syndrome.. People with increased daytime and nighttime urinary frequency who have never sought treatment are eligible to participate. Individuals also eligible to participate are people who have not yet received treatment for ...
There are many causes of overactive bladder. Symptoms of overactive bladder occur when there is abnormal increase in sensitivity of the bladder or decreased ability of the bladder to store urine. OAB can also be caused by abnormal sudden, involuntary contraction of the detrusor muscle in the wall of the bladder, which in turn causes you to void. The muscle seems to be twitchy, and its this hyper-reactivity of detrusor muscle in the bladder wall that causes you to feel you need to pee frequently and urgently even when the bladder is not full.. But life doesnt have to be this way! Doctors at the New York Urology Specialists are here to help you change that.. Fortunately, there are many treatments, and one of them is with Botox for overactive bladder. ...
Functions like filling, storing, and emptying the bladder are regulated by nerves. When these nerves become damaged, nerve signals are disrupted and loss of bladder control results.. Neurogenic bladder is often caused by an injury, tumor, or defect of the central nervous system (the brain and spinal cord). Diseases like cerebral palsy, multiple sclerosis, and neural tube defects like spina bifida also can be responsible. Sometimes nerve damage due to heavy, long-term alcohol use, diabetes, or a slipped disk will cause the problem.. Symptoms of neurogenic bladder may include frequent urination (peeing), inability to fully empty the bladder, incontinence (the accidental release of urine), and urinary retention (inability to urinate). People with the disorder are also more likely to develop urinary tract infections (UTIs).. Treatment for neurogenic bladder might include medication, strengthening exercises, or the use of a urinary catheter. Some people will need surgery to help ease symptoms.. ...
Urinary bladder cancer in cats is characterized by an abnormal growth of cells within the urinary bladder. The most common type urinary bladder cancer seen in cats is rooted from a tumor called transitional cell carcinoma (TCC).
As a research subject, the biomechanics of the urinary bladder are relatively young, yet medical problems associated with them are as old as mankind. Offering an update on recent achievements in the field, the authors highlight the underlying biological, chemical and physical processes of bladder function and present the systematic development of a mathematical model of the organ as a thin, soft biological shell. The book will be a valuable resource for postgraduate students and researchers interested in the applications of computational mathematics and solid mechanics to modern problems in biomedical engineering and medicine.
Neurogenic bladder is a condition that can develop in men and women in which the nerves that govern the urinary system and signal when urine should be held in or released from the bladder do not function properly, and patients lose bladder control. The bladder can become either overactive or underactive, depending on the origin of the problem. People can develop neurogenic bladder following trauma such as a spinal cord injury or diseases that affect the nervous system, diabetes, acute infections, genetic nerve problems, or heavy metal poisoning.
Chen B, Zhang H, Liu L, et al. PK2/PKR1 Signaling Regulates Bladder Function And Sensation In Rats With Cyclophosphamide-Induced Cystitis[J]. Mediators of Inflammation, 2015.
Bladder infection is known by its medical term as cystitis. It is one of the most common diseases affecting about six million women each day and ranks second as the common reason for patient visits. Also known as urinary tract infection, this occurs whenever E.coli bacteria are present in the urinary tract passing through the urethra. Women are most likely to have the disease than men because of the structure of their urinary system and the proximity of the rectum to the urethra.. Symptoms of bladder infection may range from mild to severe and some even disappear without need of a treatment. Most of the time, symptoms of bladder infection may be similar to having kidney problems.. Primarily though, symptoms of bladder infection usually relate to the urinary function. Nevertheless, here is a closer look at the different symptoms of bladder infection among women.. ...
Carcinoma of the urinary bladder is a common (in the USA it is the fifth most common form of cancer in males and tenth most common form of cancer in females) malignan- cy and one in which noninvasive staging by imaging plays such an important role. This book presents a complete approach to MR imaging of carcinoma of the urinary bladder from a detailed discussion of the value of MRI in the diagnosis of the urinary bladder to the history of the procedure. The technical discussion of the general principles of MRI including the optimal pulse sequences to be used and factors that influence the quality of images are included in this book. The safety factors are also presented along with contraindications. The application of a double surface coil with the field strength of O.5T provides the fine quality of the illustrations. The atlas of comparative anatomy by MRI on normal volunteers and post-mortem specimens as well as MR images on patients with bladder tumors and post-surgery specimens is unique. The
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Neurogenic bladder is bladder dysfunction that may be either flaccid or spastic. Neurogenic Bladder is caused by neurological damage. More about Neurogenic Bladder.
Purpose: The objectives of this study were to compare the functional expression of muscarinic and purinergic receptors in the urinary bladder of 2 species, rat and guinea pig under comparable experimental conditions; and to test whether the receptors in males and females differ. Methods: Reverse transcription-polymerase chain reaction (RT-PCR) techniques were used to identify gene expression profiles in bladder smooth muscle (total n=8 rats, 7 guinea pigs) and mechanical responses to nerve stimulation and applied acetylcholine (ACh) in the presence of specific antagonists were used to identify functional receptor sub-types (total n=12 rats, 16 guinea pigs). Results: RT-PCR indicated that M2 and M3 were the predominant muscarinic receptor genes in both the male and female rat and guinea pig bladders. The phasic component of the nerve-induced contraction was greater in guinea pigs vs. rats. The tonic component and the ACh response were inhibited by the M3 receptor antagonist, darifenacin (10-6 M, ...
TY - JOUR. T1 - Survival of patients with carcinoma in situ of the urinary bladder. AU - Cheng, Liang. AU - Cheville, John C.. AU - Neumann, Roxann M.. AU - Leibovich, Bradley C.. AU - Egan, Kathleen S.. AU - Spotts, Bruce E.. AU - Bostwick, David G.. N1 - Copyright: Copyright 2007 Elsevier B.V., All rights reserved.. PY - 1999/6/1. Y1 - 1999/6/1. N2 - BACKGROUND. To the authors knowledge, the long term follow-up of patients with carcinoma in situ of the urinary bladder is limited. METHODS. The authors studied 138 patients diagnosed with urothelial carcinoma in situ of the bladder at the Mayo Clinic between 1972-1979. All the histologic slides were reviewed and fulfilled the diagnostic criteria for carcinoma in situ according to the newly proposed World Health Organization and International Society of Urologic Pathology classification system. None of these patients had previous or coexisting invasive urothelial carcinoma at the time of diagnosis. Cox proportional hazards models were used to ...
It has been reported that, under physiological conditions, bladder distention by NS infusion primarily activates nonnociceptive bladder Aδ-afferent fibers, which trigger supraspinal micturition. However, under pathological conditions, bladder irritation by AA infusion activates nociceptive C-afferent fibers, which induce a spinal micturition reflex [15]. In this study, AA induced overactivity and reduced BC compared with the NS control levels (Figs. 4, 5). The sacral nerve was activated by electrical stimulation over a range of frequencies so that frequency response curves could be compared (Figs. 4, 5). We found that SNM at the 5-Hz frequency did not significantly change the BC, while SNM at the 15-, 30-, and 50-Hz frequencies significantly increased the BC during AA infusion. Moreover, no significant differences were observed in the results obtained using those 3 frequencies. This indicates that stimulation at 15 Hz seems to be sufficient to inhibit bladder activity. SNM is not ...
OAB is defined by urgency with or without urinary frequency [11,12]. In other words, urgency is a key symptom of OAB, which is associated with the appearance of DO in urodynamic studies [11]. This has serious implications for patients daily life and quality of life, so it is known that treatment to suppress DO is clinically necessary [13-15]. However, interestingly, the present study using direct gene expression microarray technology found that the bladders in which DO persisted after BOO and deobstruction showed near-normal patterns of gene expression changes. In contrast, the bladders without DO after BOO and deobstruction showed much poorer changes in gene alteration, and continued to have abnormal bladder function. They showed much more dramatically changed gene expression patterns than were found in the BOO group, and a meaningful RV, indicating functional deterioration, even though they showed a significantly reduced RV compared to the BOO group.. The above findings imply that DO does not ...
Bladder relaxation - Prostate Cancer | Medscape. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
Urinary frequency due to bladder spasm, common in older men, may be confused with prostatic hyperplasia. Statistical ... Urinary bladder (black butterfly-like shape) and hyperplastic prostate (BPH) visualized by medical ultrasonography technique ... The prostate surrounds the urethra just below the urinary bladder and can be felt during a rectal exam. ... This reduces the amount of residual volume in the bladder, increases the urinary flow rate and decreases the voiding time. ...
Post-void residual volume: Most tests begin with the insertion of a urinary catheter/transducer following complete bladder ... It helps demonstrate the reasons for difficulty in voiding, for example bladder muscle weakness or obstruction of the bladder ... Fluoroscopy (moving video x-rays) of the bladder and bladder neck during voiding. ... "Residual urinary volume and urinary tract infection--when are they linked?". J. Urol. 180 (1): 182-5. doi:10.1016/j.juro. ...
4. Urinary bladder. * 5. Urachus. * cl. Cloaca. * cp. Elevation which becomes clitoris or penis. * i. Lower part of the ... and these give rise to the trigone of urinary bladder and part of the prostatic urethra. The remainder of the vesico-urethral ... Because its location, to a large extent, overlaps the urinary system, the development of them can also be described together as ... portion forms the body of the bladder and part of the prostatic urethra; its apex is prolonged to the umbilicus as a narrow ...
... or Foot's Major Yang Urinary Bladder Meridian. Greater Yang (taiyang, 太阳). Foot (足). Water (水). Urinary bladder (膀胱). 申 [shēn] ... The Yang meridians of the leg are Stomach, Bladder, and Gall Bladder.[4] ... Gall Bladder (膽). 子 [zǐ] 11 p.m. to 1 a.m. ... Taiyang Bladder Channel of Foot (足太阳膀胱经) ...
Inside the urinary bladder. *Vagina. *Gallbladder. *Inside the stomach. *Inside the rectum ...
Bleisch VR, Konikov NF (October 1952). "Malakoplakia of urinary bladder; report of four cases and discussion of etiology". AMA ... bladder, adrenal gland, abdomen and muscle. Telling apart clinically a XP from a tumor condition can be challenging as pointed ...
Main articles: Urinary bladder and Urethra. The main organs involved in urination are the urinary bladder and the urethra. The ... Urination is the release of urine from the urinary bladder through the urethra to the outside of the body. It is the urinary ... During storage, bladder pressure stays low, because of the bladder's highly compliant nature. A plot of bladder (intravesical) ... When the external urinary sphincter is relaxed urine is released from the urinary bladder when the pressure there is great ...
Intravesical infusion is into the urinary bladder.. *intravitreal, through the eye. *Subcutaneous (under the skin).[22] This ...
In addition, he was Founding Director of the NCI-funded National Urinary Bladder Flow Cytometry Network which established ... urinary bladder flow cytometry; image analysis; holographic microscopy; robotic telepathology; quantitative ... "Changes in Plasma Membrane Structure Associated with Malignant Transformation in Human Urinary Bladder Epithelium". Cancer ... which qualified patients for inclusion in urinary bladder cancer clinical trials. ...
Primary urinary tract EMZLs of the urinary bladder and kidney are extremely rare but the most common forms of lymphoma that are ... inflammation of the bladder due to urinary tract infection or other causes. Presenting symptoms of primary bladder lymphoma ... Venyo AK (2014). "Lymphoma of the urinary bladder". Advances in Urology. 2014: 327917. doi:10.1155/2014/327917. PMC 3912819. ... Treatment of primary bladder EMZL depends on the extent of disease. Localized disease should be confirmed using, e.g. Positron ...
Urinary tract: Ureters, urinary bladder, urethra. Radical prostatectomy and radical cystectomy both require anastomosis of the ... Urinary diversion Vilhjalmsson, Dadi; Olofsson, Per; Syk, Ingvar; Thorlacius, Henrik; Grönberg, Anders (2015). "The Compression ... bladder to the urethra in order to restore continuity. Microsurgery: The advent of microsurgical technique allowed anastomoses ...
Lewin, Richard J.; Dillard, George V.; Porter, Robert W. (1967). "Extrapyramidal inhibition of the urinary bladder". Brain ...
Brosman, SA (1991). "BCG vaccine in urinary bladder cancer". West J Med. 155 (6): 633. PMC 1003114. PMID 1812634. Gradmann, ...
Long and slender gall bladder. The kidneys rounder than in humans, and the ureters are different. Longer urinary bladder No ...
Lewis, S. A.; Diamond, J. M. (1975). "Active sodium transport by mammalian urinary bladder". Nature. 253 (5494): 747-748. doi: ... and degradation of sodium channels in rabbit urinary bladder". Science. 221 (4617): 1288-1290. doi:10.1126/science.6612343. ...
Another example occurs in the urinary bladder. Intestinal metaplasia Squamous metaplasia Micrograph of Barrett's esophagus, an ... "Glandular metaplasia and mucin production in transitional cell carcinomas of bladder". J. Clin. Pathol. 24 (5): 481. doi: ...
A Description of the Human Urinary Bladder ... [together with] Animadversions on Lithontriptic Medicines, particularly those of ...
Meesa IR, Junewick JJ (August 2008). "Pelvic plexiform neurofibroma involving the urinary bladder". Pediatric Radiology. 38 (8 ... A 14-year-old girl with NF1 was diagnosed with a neurofibroma involving her bladder, a rare location. Once a plexiform ...
Transporting point of SI: Urinary Bladder 27. Conception vessel - anterior midline from perineum to lower lip. This is also the ... The turbid is sent downwards to the large intestine, while the useless water is infused to the bladder. The disorders of the ... manifesting stool and urinary disturbance, such as abdominal pain, diarrhea, scanty urine, etc. The Small intestine and its ...
Tissue Engineering of Urinary Bladder; We Still Have a Long Way to Go?". STEM CELLS Translational Medicine. 6 (11): 2033-2043. ... The two main methods for replacing bladder function involve either redirecting urine flow or replacing the bladder in situ. ... Standard methods for replacing the bladder involve fashioning a bladder-like pouch from intestinal tissue. As of 2017 methods ... "The utility of stem cells in pediatric urinary bladder regeneration". Pediatric Research. 83 (1-2): 258-266. doi:10.1038/pr. ...
The detrusor muscle, also detrusor urinae muscle, muscularis propria of the urinary bladder and (less precise) muscularis ... These fibers pass, in a more or less longitudinal manner, up the inferior surface of the bladder, over its apex, and then ... The detrusor muscle remains relaxed to allow the bladder to store urine, and contracts during urination to release urine.[1] ... At other times the muscle is kept relaxed via sympathetic branches from the inferior hypogastric plexus to allow the bladder to ...
Janis C. Kelly (26 October 2015). "Urinary Biomarkers Not Useful for Bladder Cancer Diagnosis". Medscape. Retrieved 31 December ... for its bladder cancer tests. Pacific Edge's suite of tests for bladder cancer are called CxBladder, with specialist sub-type ... "Warning over bladder cancer test". Stuff.co.nz. Retrieved 31 December 2015. "Pacific Edge sales up; still no profit". Otago ... Pacific Edge Limited is a cancer diagnostics New Zealand company that offers a genetic biomarker based suite of bladder cancer ...
Cystectomy is the removal of the urinary bladder. It also means removal of a cyst. Corpectomy is the removal of a vertebral ... Hemicorporectomy is the surgical amputation of the entire body below the waist, including the legs, genitalia, urinary system, ...
Smith, Z., Sehgal, S., Van Arsdalen, K. and Goldstein, I. (2014). Placenta Percreta With Invasion into the Urinary Bladder. ...
Histopathology of urothelial carcinoma of the urinary bladder. Histopathology of urothelial carcinoma of the urinary bladder. ... Punyavoravut V, Nelson SD (August 1999). "Diffuse bony metastasis from transitional cell carcinoma of urinary bladder: a case ... It is the most common type of bladder cancer and cancer of the ureter, urethra, and urachus. It accounts for 95% of bladder ... "Incidence and Survival of urothelial carcinoma of the urinary bladder in Norway 1981-2014". BMC Cancer. 16 (1). doi:10.1186/ ...
which also causes urinary-bladder cancer in rats. Nitrosotoluene converts hemoglobin to methemoglobin, resulting in ... Kadlubar, F. F.; Badawi, A. F. (1995). "Genetic susceptibility and carcinogen-DNA adduct formation in human urinary bladder ... More generally, chromosomal instability is known to be induced by aromatic amines in urinary bladder cells. Chromosomal ... in cultured human bladder cells and bladder cells from rats and mice exposed in vivo to o-toluidine. Metabolites of o-toluidine ...
... is used to treat urinary bladder spasms. It is available under the trade name Urispas (Paladin)(india), Genurin (by ... gastrointestinal hemorrhage and obstructive uropathies of the lower urinary tract. Dimefline Flavodilol Alvocidib (Flavopiridol ...
Urinary bladder conditions: bladder incontinence or urine retention. *Gastrointestinal tract: dysphagia, abdominal pain, nausea ... but common symptoms are poor bladder control, abnormal blood pressure or heart rate, and reduced ability to sweat normally.[4][ ... affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the ...
"Substance P and neurokinins as stimulants of the human isolated urinary bladder". Neuropeptides. 11 (2): 83-7. doi:10.1016/0143 ...
Again, because of the retention of urine, urinary tract infections are frequent. Urinary retention can lead to bladder ... Urinary symptoms include urinary frequency, urgency, incontinence and retention. ... or autonomic changes such as urinary symptoms. These changes are thought to result from microvascular injury involving small ...
"Do the urinary bladder and large bowel interact, in sickness or in health? ICI-RS 2011". Neurourology and Urodynamics. 31 (3): ... overactive bladder[21] and some medically unexplained syndromes such as fibromyalgia and multiple chemical sensitivity. ... "Does central sensitization help explain idiopathic overactive bladder?". Nature Reviews. Urology. 13 (8): 481-91. doi:10.1038/ ...
PAX gene deficiencies can result in development defects called Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). ... bladder, prostate, and endometrial carcinomas.[9] The mechanism of switching on the genes is unknown. Some studies have ...
Digital rectal exam: side view of the male reproductive and urinary anatomy, including the prostate, rectum and bladder ... for the evaluation of certain clinical symptoms: a male with change in urinary ability, impotence, or dysuria (blood in the ...
Rabie E. Abdel-Halim, Ali S. Altwaijiri, Salah R. Elfaqih, Ahmad H. Mitwall (2003), "Extraction of urinary bladder described by ...
Urinary tract infection. *Retroperitoneal fibrosis. *Urolithiasis *Bladder stone. *Kidney stone. *Renal colic ...
Turtles have two or more accessory urinary bladders, located lateral to the neck of the urinary bladder and dorsal to the pubis ... In some reptiles, a midventral wall in the cloaca may open into a urinary bladder, but not all. It is present in all turtles ... Davis, Jon R.; DeNardo, Dale F. (2007-04-15). "The urinary bladder as a physiological reservoir that moderates dehydration in a ... Some are also able to take up water stored in the bladder. Excess salts are also excreted by nasal and lingual salt glands in ...
... rarely cancers of the alimentary tract and urinary bladder); possibly responsible for the skin tumour equine sarcoid in horses ...
Main articles: Urinary bladder and Urethra. The main organs involved in urination are the urinary bladder and the urethra. The ... Urination is the release of urine from the urinary bladder through the urethra to the outside of the body. It is the urinary ... During storage, bladder pressure stays low, because of the bladder's highly compliant nature. A plot of bladder (intravesical) ... When the external urinary sphincter is relaxed urine is released from the urinary bladder when the pressure there is great ...
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Urinary tract infection. *Retroperitoneal fibrosis. *Urolithiasis *Bladder stone. *Kidney stone. *Renal colic ...
Urinary tract infection. *Retroperitoneal fibrosis. *Urolithiasis *Bladder stone. *Kidney stone. *Renal colic ...
This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.. *v ... "Fesoterodine, New Drug Candidate For Treatment For Overactive Bladder - Pfizer To Acquire Exclusive Worldwide Rights". Medical ... "Pfizer's Toviaz (fesoterodine fumarate) Receives FDA Approval for the Treatment of Overactive Bladder" (Press release). Pfizer ... is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome (OAB).[1] It was approved by the ...
Nikibakhsh, Ahmad (Sep 2011). "16". Clinical Management of Complicated Urinary Tract Infection. doi:10.5772/24859. ISBN 978-953 ... Use of forearm free-flap phalloplasty in bladder exstrophy adults by Marc-Olivier Timsit, Pierre Mouriquand, Alain Ruffion, ... Before the incision is made, a Foley catheter is inserted in the bladder through the urethra. ...
... inflammation and bleeding from the bladder, and bladder cancer.[8] In contrast, administering pulsed doses of intravenous ... Kidneys: urinary sediment with: *microscopic hematuria or. *red cell casts. *Biopsy: granulomatous inflammation *. ...
Urinary tract infection. *Retroperitoneal fibrosis. *Urolithiasis *Bladder stone. *Kidney stone. *Renal colic ... Microalbuminuria (moderate increase in the levels of urinary albumin) is a non-specific finding in patients with vascular ...
A urinary tract infection may involve only the lower urinary tract, in which case it is known as a bladder infection. ... A urinary tract infection (UTI) is an infection that affects part of the urinary tract.[1] When it affects the lower urinary ... Urinary catheters. Urinary catheterization increases the risk for urinary tract infections. The risk of bacteriuria (bacteria ... Lower urinary tract infection is also referred to as a bladder infection. The most common symptoms are burning with urination ...
urinary/. breast. Ovarian tumor. *Surface epithelial-stromal tumor *CA-125. *EC *CD30 ...
The penis and testes are located internally between the rectum and urinary bladder in males, and females have a single pair of ...
... and extends to the inguinal canal to the wall of the scrotum as a testis to sense it passes to the side of the urinary bladder ... The development of the male reproductive system coincides with the urinary system. The development of them can also be ...
The bladder is often small, nondistensible and may be filled with a minute amount of fluid. In males the vas deferens and ... atresia of the ureter or urethra causing obstruction of the urinary tract, polycystic or multicystic kidney diseases, renal ... The mesonephric duct(s) of the agenic kidney(s) will also degenerate and fail to connect with the bladder. Therefore, the means ... by which the fetus produces urine and transports it to the bladder for excretion into the amniotic sac has been severely ...
The organs known as the accessory digestive organs are the liver, gall bladder and pancreas. Other components include the mouth ... This is to the right of the stomach and it overlies the gall bladder. The liver synthesises bile acids and lecithin to promote ... This is achieved in the duodenum by the addition of bile from the gall bladder combined with the bicarbonate secretions from ... Bile flows from the liver through the bile ducts and into the gall bladder for storage. The bile is released in response to ...
spinal cord, particularly the area where some control of the bladder and bowel resides. ... urinary incontinence and constipation. ...
Painful sexual act may be one of the first symptoms of cystitis (a bladder infection). People with cystitis may have bladder ... Women with cystitis usually also have urinary frequency (needing to urinate a lot) and/or urinary urgency (needing to urinate ... Some of the most common physical causes are infections of the vagina, urinary tract, cervix, or fallopian tubes; endometriosis ... Infections of the prostate, bladder, or seminal vesicles can lead to burning or itching sensations following ejaculation. Men ...
GU: Urinary system. വൃക്ക · Ureter · Bladder · Urethra. GU: പ്രത്യുത്പാദനേന്ദ്രിയ വ്യൂഹം. Female (ഗർഭപാത്രം, ഭഗം, അണ്ഡാശയം, ...
Urinary tract infection. *Retroperitoneal fibrosis. *Urolithiasis *Bladder stone. *Kidney stone. *Renal colic ... A urinalysis will show red blood cells, usually as red cell urinary casts. Proteinuria, usually less than 2 grams per day, also ... These tests would rule out kidney stones and bladder cancer, two other common urological causes of hematuria. In children and ... Johann Lukas Schönlein described a syndrome of purpura associated with joint pain and urinary precipitates in children. Eduard ...
... a retrograde urethrogram should be performed before attempting to place a Foley catheter into the bladder. If there is a ...
... s do not have a urinary bladder or external urethral opening and (with exception of the ostrich) uric acid is excreted ...
Bladder emptying was significantly improved, while there was a trend towards a higher urinary flow and shorter voiding time.[ ... Cystoscopy shows the urinary tract from inside the bladder, using a thin, flexible camera tube inserted down the urethra. ... under the urinary bladder and in front of the rectum. The prostate surrounds part of the urethra, the tube that carries urine ... Changes within the gland, therefore, directly affect urinary function. Because the vas deferens deposits seminal fluid into the ...
In the winter of 1723, Peter, whose overall health was never robust, began having problems with his urinary tract and bladder. ... An autopsy revealed his bladder to be infected with gangrene.[9] He was fifty-two years, seven months old when he died, having ... This icy water rescue is said to have exacerbated Peter's bladder problems and caused his death. The story, however, has been ...
Bladder dysfunction with urinary retention[39]. *Constipation[39]. *Brudziński's sign[38]. *Vertigo ... This inflammation can lead in the short term to paralysis, bladder dysfunction, visual disturbance, and coma and in the long ...
... or the loss of bladder control causing urine leakage is a common but treatable problem. Causes, diagnosis, and treatment ... Urinary control relies on the finely coordinated activities of the smooth muscle tissue of the urethra and bladder, skeletal ... Better Bladder Control. Up to 54% of people with symptoms of bladder control problems havent talked to their doctor. ... Urinary incontinence can result from anatomic, physiologic, or pathologic (disease) factors. Congenital and acquired disorders ...
Urinary bladder. 1. Human urinary system: 2. Kidney, 3. Renal pelvis, 4. Ureter, 5. Urinary bladder, 6. Urethra. (Left side ... Histology at KUMC epithel-epith09 "Urinary Bladder". *Anatomy photo: Urinary/mammal/bladder/bladder1 - Comparative Organology ... Turtles have two or more accessory urinary bladders, located lateral to the neck of the urinary bladder and dorsal to the pubis ... "SEER Training:Urinary Bladder". training.seer.cancer.gov.. *^ a b c Viana R, Batourina E, Huang H, Dressler GR, Kobayashi A, ...
... urinary bladder (sco); urinblære (nn); urinblære (nb); Sidiklik (az); ಮೂತ್ರಕೋಶ (kn); میزەڵدان (ckb); urinary bladder (en); ... urinary bladder (en-gb); Harnblase (als); Пикочен мехур (bg); Bladder (simple); urinblåsa (sv); Сечовий міхур (uk); 膀胱懸垂體 (zh- ... "Urinary bladder" 분류에 속하는 미디어. 다음은 이 분류에 속하는 파일 14개 가운데 14개입니다. ... Urinary bladder (en-ca); మూత్రాశయం (te); Vezică urinară (ro); Vexiga urinaria (gl); שלפוחית השתן (he); Ουροδόχος κύστη (el); ...
Urinary incontinence is the loss of bladder control. This means you cant always control when you urinate. Most types of ... Bladder training is a common treatment.. What is bladder training?. Bladder training is a way of learning to manage urinary ... Urinary Incontinence. Urinary incontinence is the loss of bladder control. This means that you cant always control when you ... Urinary incontinence is the loss of bladder control. This means you cant always control when you urinate. There are different ...
The urinary bladder is made of several distinct tissue layers:. *The innermost layer of the bladder is the mucosa layer that ... The urinary bladder functions as a storage vessel for urine to delay the frequency of urination. It is one of the most elastic ... In females the urinary bladder is somewhat reduced in size and must share the limited space of the pelvic cavity with the ... The urinary bladder is a hollow elastic organ that functions as the bodys urine storage tank. Urine produced by the kidneys ...
Macroscopic examination of LUBs show large discrete tumours centred in the dome or lateral walls of the bladder. Positive ... LUB presents with haematuria, dysuria, urinary frequency, nocturia, and abdominal or back pain. ... i,Background,/i,. Lymphoma of the urinary bladder (LUB) is rare. ,i,Aims,/i,. To review the literature on LUB. ,i,Methods,/i,. ... Lymphoma of the urinary bladder can be either (a) primary lymphoma of the urinary bladder and this is a rare lymphoma ...
... (LUB) is rare. Aims. To review the literature on LUB. Methods. Various internet databases were ... Lymphoma of the Urinary Bladder. Anthony Kodzo-Grey Venyo North Manchester General Hospital, Department of Urology, Delaunays ... Macroscopic examination of LUBs show large discrete tumours centred in the dome or lateral walls of the bladder. Positive ... LUB presents with haematuria, dysuria, urinary frequency, nocturia, and abdominal or back pain. ...
Learn about urinary incontinence treatments and products that can help. ... Get the facts about bladder control problems like overactive bladder, urge incontinence, and stress incontinence. ... Urinary Incontinence in Women Urinary incontinence, or loss of bladder control, is a frustrating problem for more than 13 ... Your bladder holds liquid waste -- urine -- until its time to get rid of it. Find out more from WebMD about how your bladder ...
Learn about urinary incontinence treatments and products that can help. ... Get the facts about bladder control problems like overactive bladder, urge incontinence, and stress incontinence. ... If you have urinary problems, your doctor may need to know how much urine stays in your bladder after you pee. A post-void ... What is Bladder Prolapse Surgery? When a womans bladder sags out of place in her abdomen and breaks through into the vagina, ...
... www.mayoclinic.org/drugs-supplements/hexaminolevulinate-urinary-bladder-route/precautions/drg-20074307 ... Bladder spasm-Use with caution. May make these conditions worse. Proper Use. A nurse or other trained health professional will ... The tube will be taken out and the medicine must be held in the bladder for at least 1 hour. You may stand, sit, or move during ... Bladder cancer that was treated with BCG (Bacillus Calmette-Guerin) solution in the past 90 days or ...
This inflammation of urinary bladder is highly chronic and leads to urgent and frequent need to urinate. The infection can also ... It is connected to the urinary bladder which passes the urine as soon as a signal from the brain is received.... Read ,. Author ... But canine bladder enlargement and urinary track infections can ... Read ,. Author: Jeff Grill ... Unfortunately, bladder problems in pets are becoming all too common. A canine thickened bladder wall can be a debilitati... ...
Urinary Incontinence, Functional Incontinence, Low Pressure Urethra, Overflow Incontinence, Stress Incontinence, Pelvic Floor ... Urinary Bladder Disorders is a chapter in the book, Urology, containing the following 9 pages: Interstitial Cystitis, ...
... such as the detrusor of the urinary bladder, exhibit a variety of spikes that differ markedly in their amplitudes and time ... Wang, X., Maake, C., Hauri, D., H, J. (2001). Occurrence of gap junctions in the urinary bladder. European Urology, 39(5 (Suppl ... Certain smooth muscles, such as the detrusor of the urinary bladder, exhibit a variety of spikes that differ markedly in their ... Bramich, N.J., & Brading, A.F (1996). Electrical properties of smooth muscle in the guinea-pig urinary bladder. The Journal of ...
The pressure within the bladder must be lower than the urethral pressur... more ... the bladder accumulates increasing volumes of urine while the pressure inside the bladder remains low. ... Drugs & Diseases , Urology , Neurogenic Bladder Q&A What happens during the filling phase of urinary bladder function?. Updated ... Rackley RR, Abdelmalak JB, El-Azab A. Laparoscopic Bladder Augmentation, Urinary diversion. Urinary Diversion. 2005. 39:363-375 ...
Urinary bladder catheters are used for urinary drainage or as a means to collect urine for measurement. Many clinical ... Urinary bladder catheters are used for urinary drainage or as a means to collect urine for measurement. Many clinical ... Complications of urinary bladder catheters and preventive strategies. Author. Anthony J Schaeffer, MD. Anthony J Schaeffer, MD ... Recurrent urinary tract infections as a result of chronic catheter use can lead to acute or chronic pyelonephritis, or bladder ...
The exact etiology of urinary bladder cancer is unknown. However, exposure to various risk factors may change the ... Urinary bladder cancer is the most common cancer of urinary tract. ... Urinary bladder cancer is the most common cancer of urinary tract. The exact etiology of urinary bladder cancer is unknown. ... Epidermal growth factor receptor expression in urinary bladder cancer. Indian J Urol. 2011;27:208-14.PubMedCentralCrossRef ...
Many women suffer from urinary discomfort, but are undiagnosed due to embarrassment. Here are solutions to different urinary ... DIAGNOSIS Overactive bladder/urge incontinence (or "tiny bladder syndrome"). WHATS HAPPENING Your bladder is calling the shots ... Out: cranberry juice to treat bladder infections. In: behavioral therapy for "tiny bladder syndrome.") ... resulting in more pressure on your bladder and on your urethra - the tube that carries urine out of your bladder. ...
We conducted a genome-wide SNP association study on 1,803 urinary bladder cancer (UBC) cases and 34,336 controls from Iceland ... Kari Stefansson and colleagues report results of a genome-wide association study for urinary bladder cancer. The strongest ... neoplasms of the urinary bladder. Bladder Consensus Conference Committee. Am. J. Surg. Pathol. 22, 1435-1448 (1998). ... Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. *Lambertus A Kiemeney1. ,2. ,3. na1, ...
However, the cancer recurred in the urinary bladder 3 months after TUR-BT. Radical cystectomy was performed, and the disease ... On pathological examination at the time of radical cystectomy, the lesion was sarcomatoid carcinoma of the urinary bladder. ... The patient was a 62-year-old female with bladder carcinoma. TUR-BT was performed in March 2010, and the pathological finding ... "Sarcomatoid Carcinoma of the Urinary Bladder" written by Kenji Shimodaira, Isao Kuroda, Naohiro Kamoda, Takuya Ishida, ...
Urinary bladder cancer in dogs may be frequently met in older dogs, and the precise causes of this condition havent been ... The diagnostics of urinary bladder cancer can be done based on the symptoms displayed by the pet and several other clinical ... A urine test can give some hints about the presence of a tumor or cancerous cells in the urinary bladder. The vet will analyze ... An early detection of urinary bladder cancer can be treatable, so it is important to get a diagnosis as soon as you suspect ...
... refractory overactive bladder (OAB), interstitial cystitis/bladder pain syndrome (IC/BPS), lower urinary tract symptoms, benign ... Measuring urinary 8-hydroxy-2-deoxyguanosine and malondialdehyde levels in women with overactive bladder. In this study, we ... Overactive bladder (OAB) is characterized by urinary urgency with or without urge incontinence, accompanied by frequency and ... The prevalence of hyperactive-type lower urinary tract symptoms is 45.2%, with shares of overactive bladder (OAB) and urge ...
Neomycin-polymyxin or gentamicin bladder instillations decrease symptomatic urinary tract infections in neurogenic bladder ... Recurrent urinary tract infections (UTIs) are common in patients with neurogenic bladder (NGB) performing clean intermittent ... Early postnatal bladder function in fetoscopic myelomeningocele repair patients. Prenatal repair of myelomeningocele (MMC) via ... Neurogenic bladders (NGB) with detrusor leak point pressures ,40 cm H2O (dLPP , 40) have been associated with deterioration of ...
Molecular determinants of tumor recurrence in the urinary bladder.. Cheng L1, Zhang S, Davidson DD, MacLennan GT, Koch MO, ... Tumor recurrence is a major clinical concern for patients with urothelial carcinoma of the urinary bladder. Traditional ... However, molecular and genetic analyses offer new perspectives on the prediction of bladder tumor recurrence. Recent studies ... The molecular changes may additionally prove useful for developing preventive and therapeutic strategies for urothelial bladder ...
Overactive bladder (OAB), stress incontinence, and urge incontinence can be treated. Learn more about the types of urinary ... Urinary incontinence in women is a common problem. ... Bladder Training for Urinary Incontinence. Stick to a Schedule ... What Is Urinary Incontinence?. Urinary incontinence refers to a loss or leaking of urine due to faulty bladder control. An ... "Bladder Training for Urinary Incontinence.". *American Family Physician: "Selecting Medications for the Treatment of Urinary ...
Squamous papilloma is a rare benign neoplasm seen in the bladder. It is composed of papillary cores with overlying ... encoded search term (Pathology of Urinary Bladder Squamous Papilloma) and Pathology of Urinary Bladder Squamous Papilloma What ... Pathology of Urinary Bladder Squamous Papilloma Updated: Jul 31, 2013 * Author: Antonio Lopez-Beltran, MD, PhD; Chief Editor: ... Noninvasive squamous lesions in the urinary bladder: a clinicopathologic analysis of 29 cases. Am J Surg Pathol. 2006 Jul. 30(7 ...
This empties the bladder on a schedule. Some men see a physical therapist and do pelvic floor exercises that help with bladder ... What are the main causes for less bladder control. * Should we add anti-inflammatory to Genurin make it more effective * Are ... The problem under question is Frequency and incontinent in affection of the bladder and prostate such as cystitis and ... https://www.nia.nih.gov/health/urinary-incontinence-older-adults. One thing that can be successful is timed voiding. ...
Overactive Urinary BladderA Study to Compare the Effectiveness and Safety of Fesoterodine and Placebo in an Elderly Population ... Urinary Bladder, Overactive Intervention Drug: Tolterodine tartrate Detrusitol® Capsule 2mg and 4mg, depending on the ... Overactive Urinary BladderA Study to Evaluate the Efficacy of Tolterodine Prolonged Release Compared With Propiverine for the ... Overactive Urinary BladderA Study to Evaluate the Efficacy of Tolterodine on Specific Symptoms in Adult Patients With ...
urinary bladder definition: a saclike structure in many animals, serving for temporary storage of fluid or semifluid excretions ... urinary bladder definition: a saclike structure in many animals, serving for temporary storage of fluid or semifluid excretions ... urinary bladder. urinary bladder. a saclike structure in many animals, serving for temporary storage of fluid or semifluid ... "urinary bladder." YourDictionary, n.d. Web. 13 November 2018. ,https://www.yourdictionary.com/urinary-bladder,. ...
All MeSH CategoriesDiseases CategoryMale Urogenital DiseasesUrologic DiseasesUrinary Bladder DiseasesUrinary Bladder Neoplasms ... "urinary bladder neoplasms"[MeSH Terms] OR Urinary Bladder Neoplasms[Text Word]. Search. ... Diseases and Pregnancy ComplicationsFemale Urogenital DiseasesUrologic DiseasesUrinary Bladder DiseasesUrinary Bladder ... Cancer of Bladder. All MeSH CategoriesDiseases CategoryNeoplasmsNeoplasms by SiteUrogenital NeoplasmsUrologic NeoplasmsUrinary ...
Tips to help prevent bladder problems in women and men, including eating and drinking right, keeping a healthy weight, and ... Prevention of Bladder Control Problems (Urinary Incontinence) & Bladder Health. How can I prevent bladder control problems?. ... You cant always prevent bladder control problems such as urinary incontinence (UI), but good habits may keep your bladder as ... Some people say smoking makes their bladder irritation worse.. Avoid constipation. Constipation can make urinary tract health ...
  • Urinary control relies on the finely coordinated activities of the smooth muscle tissue of the urethra and bladder, skeletal muscle, voluntary inhibition, and the autonomic nervous system. (healthcommunities.com)
  • Urine enters the bladder via the ureters and exits via the urethra . (wikipedia.org)
  • Urine leaves the bladder via the urethra , a single muscular tube ending in an opening - the urinary meatus , where it exits the body. (wikipedia.org)
  • The neck of the bladder is the area at the base of the trigone that surrounds the internal urethral orifice that leads to the urethra. (wikipedia.org)
  • The trigone is a smooth-muscle area that forms the floor of the bladder above the urethra. (wikipedia.org)
  • Urine produced by the kidneys flows through the ureters to the urinary bladder, where is it stored before passing into the urethra and exiting the body. (innerbody.com)
  • A small funnel forms at the inferior end of the urinary bladder leading into the urethra, the tube that carries urine out of the body during urination. (innerbody.com)
  • Another separate muscle, the external urethral sphincter, surrounds the urethra just inferior to the bladder and helps to control and delay urination through its contraction. (innerbody.com)
  • WHAT'S HAPPENING Pregnancy, childbirth, extra pounds, declining estrogen levels in perimenopause and menopause, and normal age-related muscle loss can all weaken pelvic-floor muscles, resulting in more pressure on your bladder and on your urethra - the tube that carries urine out of your bladder. (goodhousekeeping.com)
  • A specially fitted vaginal pessary, a rubber device somewhat like a contraceptive diaphragm, can lift your bladder and keep your urethra shut. (goodhousekeeping.com)
  • Weakness of the pelvic floor muscles and tissues that support the bladder and urethra causes stress incontinence. (medicinenet.com)
  • Stress urinary incontinence occurs when laughing, sneezing, coughing or exercising, and is caused by weakness in the muscles and ligaments that support the bladder and urethra, or deficient urethral sphincter muscles. (bidmc.org)
  • Support of the urethra and bladder neck is thought to be important in the maintenance of continence during sudden increases in intra-abdominal pressure. (medscape.com)
  • The bladder neck (posterior urethra) is 2 to 3 centimeters long, and its wall is composed of detrusor muscle interlaced with a large amount of elastic tissue. (scribd.com)
  • Beyond the posterior urethra, the urethra passes through the urogenital diaphragm, which contains a layer of muscle called the external sphincter of the bladder. (scribd.com)
  • Anatomical assessment of the bladder outlet and proximal urethra using ultrasound and videocystourethrography. (medscape.com)
  • When bacteria travels up the urethra, it can travel into the bladder or kidneys, causing infection . (rxlist.com)
  • Complete medical history and thorough physical examination including rectal examination to evaluate the urethra, bladder neck, prostate gland in males and local lymph nodes. (petplace.com)
  • Abdominal ultrasound to evaluate for tumors in the bladder and urethra, stones in the urinary tract, or urinary tract obstruction. (petplace.com)
  • Each urinary bladder receives the ureter of the ipsilateral kidney and is drained by its own urethra, with the ureter and urethra lying side by side. (thefreelibrary.com)
  • In some cases, only 1 bladder communicates with a single urethra, leaving the opposite side obstructed with no outlet. (thefreelibrary.com)
  • Each urethra originates from a separate urinary bladder. (thefreelibrary.com)
  • In most cases there is associated duplication of the urethra, but in a few cases, only 1 bladder communicates with a single urethra, leaving the opposite side obstructed with no outlet. (thefreelibrary.com)
  • Bladder neck slings are placed at the level of the proximal urethra or bladder neck. (uptodate.com)
  • In connection with the post-operative care of gynecologic patients and other surgical procedures where voiding is a problem, it is a common practice to insert a catheter through the urethra and into the bladder to effect drainage of the bladder. (freepatentsonline.com)
  • An object of the present invention is to provide a method and system for suprapubic drainage from the bladder which eliminates the need for repeated insertions and withdrawals of a catheter through the urethra. (freepatentsonline.com)
  • This process uses stitches to support the bladder and urethra. (portsmouthhospital.com)
  • The urethra is the tube that carries urine from the bladder to the outside of the body. (portsmouthhospital.com)
  • Muscles in the pelvis support the bladder and urethra. (portsmouthhospital.com)
  • The vaginal wall is also close to the bladder and urethra. (portsmouthhospital.com)
  • If the vaginal walls are weak, the bladder and urethra may not work properly. (portsmouthhospital.com)
  • A bladder suspension lifts the bladder and urethra by securing it to nearby pelvic structures like to the pelvic bone. (portsmouthhospital.com)
  • Lifting the bladder makes it easier for the bladder to close to stop urine leakage into the urethra. (portsmouthhospital.com)
  • The urethra, which is the tube from the bladder where the urine flows, is often kinked like a garden hose and causes the bladder to empty poorly. (adventisthealth.org)
  • The two ureters enter the bladder at ureteric orifices, and the urethra enters at the trigone of the bladder. (wikipedia.org)
  • When the bladder 'signals' the urge to urinate, the urine then leaves the bladder through the urethra. (mindfood.com)
  • When infection occurs in the bladder (cystitis) and inside the urethra (urethritis) it can cause severe discomfort and pain. (mindfood.com)
  • UTIs or Urinary Tract Infections occur when micro-organisms such as bacteria build up in either the urethra or bladder and are most commonly experienced by women. (mindfood.com)
  • This is due to the size of the urethra being much smaller and straighter than a male's urethra, therefore making it easier for germs to travel into the bladder. (mindfood.com)
  • Recent studies have revealed the presence of lesions in both the bladder and the urethra. (wearethecure.org)
  • The rectal examination may reveal thickening of the wall of the urethra or trigone region of the bladder, enlargement of iliac lymph nodes, mass in the bladder or a distended bladder. (wearethecure.org)
  • To address these issues, we have modified the condom for passing a catheter into the urethra for simultaneous direct bladder and back-pressure recording. (biomedsearch.com)
  • It was facilitated by bladder or urethra exposure to cold and menthol, stimuli that activate specific cold-sensitive receptors associated with unmyelinated C afferents. (diva-portal.org)
  • Coloured retrograde and urinary urethrocystography image (bladder and urethra X-ray) using a contrast medium to examine the bladder and urinary tract of a 24-year-old woman who has recurring urinary tract infections. (sciencephoto.com)
  • The urine is ultimately excreted from the bladder through the urethra. (histology-world.com)
  • Weak bladder muscles -- caused by nerve damage from diabetes or other diseases -- or a blocked urethra can be responsible. (digitalnaturopath.com)
  • Urinary retention can result from obstruction of the urethra, nerve problems, nerve problems, medications and weakened bladder muscles. (empowher.com)
  • A UTI can affect the bladder, kidney, ureters and/or the urethra. (ehealthforum.com)
  • If your normally happy-go-lucky dog falls prey to a bladder infection, it can be an ugly scene. (articlealley.com)
  • Bacteriuria and urinary tract infection - The presence of bacteria in the urine is almost universal in patients with catheters in place for over one week. (uptodate.com)
  • The evaluation of bacteriuria and diagnosis of catheter-associated urinary tract infection is discussed in detail elsewhere. (uptodate.com)
  • See 'Catheter-associated urinary tract infection in adults', section on 'Asymptomatic bacteriuria' and 'Catheter-associated urinary tract infection in adults', section on 'Diagnosis' . (uptodate.com)
  • These symptoms can also point to a urinary infection, so the vet may prescribe some antibiotics. (vetinfo.com)
  • You're also more likely to develop a bladder infection if you hold urine in. (nih.gov)
  • What are the different types of urinary tract infection and bladder infection medicines? (rxlist.com)
  • Bladder infection is called cystitis . (rxlist.com)
  • What are common side effects of urinary tract infection and bladder infection medications? (rxlist.com)
  • Side effects of antibiotics used to treat urinary tract infection and bladder infection include nausea , diarrhea , dizziness , lightheadedness , headache , or trouble sleeping. (rxlist.com)
  • Side effects of urinary tract and bladder infection pain relievers include headache, dizziness, or stomach upset. (rxlist.com)
  • Where can people find more information about side effects of prescription urinary tract infection and bladder infection drugs? (rxlist.com)
  • For more information about side effects of urinary tract infection and bladder infection medications, search for the drug and click on the drug's "Side Effects Center" on the top left side of the page. (rxlist.com)
  • Bacterial lower urinary tract infection (UTI or cystitis). (petplace.com)
  • Gravity drainage of the bladder is avoided and the system prevents back flow of urine into the bladder, which might cause infection. (freepatentsonline.com)
  • Bladder spasms can result from dietary factors (bladder stimulants-caffeine or alcohol), increased fluid intake, drug side effects, urinary tract infection/cancer, and/or nerve dysfunction (associated with nerve trauma, diabetes, multiple sclerosis, or spinal cord injury). (brighamandwomens.org)
  • Urachal diverticula also predispose to urinary tract infection by serving as a nidus for bacteria. (merckvetmanual.com)
  • Sensation from the bladder, relating to distension or to irritation (such as by infection or a stone) is transmitted primarily through the parasympathetic nervous system. (wikipedia.org)
  • Rabbits that have been diagnosed with a urinary tract infection are usually treated as outpatient. (petmd.com)
  • Cystitis is common, sometimes referred to as urinary tract infection (UTI) caused by bacteria, bladder rupture occurs when the bladder is overfilled and not emptied while bladder tamponade is a result of blood clot formation near the bladder outlet. (wikipedia.org)
  • It is most commonly caused by a bacterial infection in which case it is referred to as a urinary tract infection. (wikipedia.org)
  • Irritative voiding symptoms in women are most often due to uncomplicated urinary tract infection. (prohealth.com)
  • Bladder cancer begins in the lining of the bladder and often shows symptoms similar to bladder infection, but the two are not directly related. (sharecare.com)
  • Recurring bladder infections may indicate bladder cancer, but only a doctor can confirm the cause of your bladder infection. (sharecare.com)
  • Often people are not even aware they have this condition until they develop another problem, such as urinary incontinence, which is loss of bladder control, resulting in the accidental loss of urine or a urinary tract infection (UTI), an illness caused by harmful bacteria growing in the urinary tract. (empowher.com)
  • Does a fever always accompany a bladder infection? (sharecare.com)
  • Children may sometimes run a fever with a bladder infection. (sharecare.com)
  • If your child has a high fever without signs of a cold for more than a day, consult a doctor to check for a bladder infection. (sharecare.com)
  • Fever is not a common sign of bladder infection for adults but may occur, especially if the infection has spread. (sharecare.com)
  • Doctors may assume a patient is suffering yet another urinary tract infection (UTI) rather than investigating for potential cancer, they said. (eveningexpress.co.uk)
  • Dr Richard Roope, Cancer Research UK's GP expert, said: "GPs see many patients with symptoms suggestive of a urinary infection - thankfully the vast majority will never go on to develop kidney or bladder cancer. (eveningexpress.co.uk)
  • Learn which symptoms indicate urinary tract infection, complications and when to seek help. (ehealthforum.com)
  • Catheter associated urinary tract infections. (medscape.com)
  • Antibiotic prophylaxis for urinary tract infections in children with spina bifida on intermittent catheterization. (medscape.com)
  • Intermittent catheterization with a hydrophilic-coated catheter delays urinary tract infections in acute spinal cord injury: a prospective, randomized, multicenter trial. (medscape.com)
  • Recurrent urinary tract infections as a result of chronic catheter use can lead to acute or chronic pyelonephritis, or bladder cancer. (uptodate.com)
  • Out: cranberry juice to treat bladder infections. (goodhousekeeping.com)
  • Neomycin-polymyxin or gentamicin bladder instillations decrease symptomatic urinary tract infections in neurogenic bladder patients on clean intermittent catheterization. (urotoday.com)
  • Recurrent urinary tract infections (UTIs) are common in patients with neurogenic bladder (NGB) performing clean intermittent catheterization (CIC) treated with or without oral antibiotic prophylaxis. (urotoday.com)
  • Bladder infections can cause UI. (nih.gov)
  • Bladder infections are relatively common in dogs and cause signs similar to those seen with bladder cancer. (petplace.com)
  • Urinary bladder anomalies are generally diagnosed in infancy or childhood when causes of urinary tract infections are evaluated. (thefreelibrary.com)
  • This disease can cause chronic urinary tract infections. (wikidoc.org)
  • This can also lead to frequent urinary tract infections. (adventisthealth.org)
  • Bovine cystitis and pyelonephritis are infections of the urinary tract by opportunistic and environmental bacteria. (merckvetmanual.com)
  • Patent urachus is typically associated with continuous urinary incontinence, urine scalding of the ventral abdomen, and development of bacterial urinary tract infections. (merckvetmanual.com)
  • Urinary tract infections (UTIs) are very common, particularly in women, and result in major costs related to antibiotic use, hospitalisations as well as time lost from work," said Dr. Deborah Wing, a gynaecology professor at University of California, Irvine. (mindfood.com)
  • A cost-effective approach to the treatment of urinary tract infections is a reasonable first step. (prohealth.com)
  • Can bladder infections lead to bladder cancer? (sharecare.com)
  • Bladder infections are most commonly caused by bacteria and blood in the urine is a less common symptom. (sharecare.com)
  • Recurring urine infections could mask the symptoms of bladder or kidney cancer, researchers have warned. (eveningexpress.co.uk)
  • The NHS website says urinary infections, which affect more women than men, can often be treated with a long course of antibiotics if they keep coming back. (eveningexpress.co.uk)
  • Read here for more on what causes urinary tract infections and what puts you at risk of UTI. (ehealthforum.com)
  • Although more common in women, both sexes are prone to bladder infections. (victoriahealth.com)
  • The modern Latin word for "bladder" - cystis - appears in associated terms such as cystitis (inflammation of the bladder). (wikipedia.org)
  • Clinical application of intravesical botulinum toxin type A for overactive bladder and interstitial cystitis. (urotoday.com)
  • After decades of clinical and basic science research, the clinical application of botulinum toxin A (Botox) in urology has been extended to neurogenic detrusor overactivity (NDO), idiopathic detrusor overactivity, refractory overactive bladder (OAB), interstitial cystitis/bladder pain syndrome (IC/BPS), lower urinary tract symptoms, benign prostatic hyperplasia, and neurogenic or non-neurogenic lower urinary tract dysfunction in children. (urotoday.com)
  • The problem under question is Frequency and incontinent in affection of the bladder and prostate such as cystitis and prostatitis. (medhelp.org)
  • Interstitial cystitis is a bladder disease of unknown etiology characterized by a bladder wall infiltrated by inflammatory cells resulting in ulcerated mucosa and scarring, spasm of the detrusor muscle, hematuria, urgency, increased frequency, and pain on urination. (wikidoc.org)
  • Urinary bladder disease includes urinary bladder inflammation such as cystitis, bladder rupture and bladder obstruction (tamponade). (wikipedia.org)
  • Cystitis is a urinary bladder inflammation that results from any one of a number of distinct syndromes. (wikipedia.org)
  • Tumors or cancer of the URINARY BLADDER. (nih.gov)
  • The atlas of comparative anatomy by MRI on normal volunteers and post-mo'rtem specimens as well as MR images on patients with bladder tumors and post-surgery specimens is unique. (springer.com)
  • Paragangliomas of the urinary bladder are very rare tumors that originate from chromaffin tissue of the sympathetic nervous system associated with the urinary bladder. (appliedradiology.com)
  • 9 Malignant paragangliomasof the bladder constitutes 10-15% of these tumors. (appliedradiology.com)
  • Benign tumors of the bladder. (petplace.com)
  • Polyps and other benign growths such as leiomyomas, which are benign tumors of smooth muscle, can occur in the bladder but are quite rare. (petplace.com)
  • Itzchak Y, Singer D, Fischelovitch Y. Ultrasonographic assessment of bladder tumors. (springer.com)
  • There are various types of bladder tumors like squamous cell carcinoma (arise in the epithelial cells), adenocarcinoma (arise in the glandular epithelium), undifferentiated carcinoma, rhabdomyosarcoma (tumor of the striated muscle- form of fibers combined into parallel fibers like the skeletal and the cardiac muscles), fibroma (tumors made of fibrous or connective tissue. (wearethecure.org)
  • Using its Guidelines for Carcinogen Risk Assessment published September 24, 1986 (51 FR 33992) the Carcinogenicity Peer Review Committee (CPRC) has classified bifenthrin as a Group C chemical, possible human carcinogen, based on urinary bladde r tumors in mice, but did not recommend assignment of a cancer potency factor Q* (Q star) for a linear quantitative cancer risk assessment, instead, the CPRC recommended the RfD approach. (fluoridealert.org)
  • Tumors of the urinary bladder were observed and initially reported as leiomyosarcomas. (fluoridealert.org)
  • Subsequently, the bladders were reviewed and the tumors showed a pattern of both epithelioid cells and spindle cells forming irregular vascular channels. (fluoridealert.org)
  • The tumors appeared to arise from the trigone of the bladder and, in some cases, invaded the bladder wall. (fluoridealert.org)
  • Boorman GA, Hollander CF (1974) High incidence of spontaneous urinary bladder and ureter tumors in the brown Norway rat. (springer.com)
  • Chomette G, Tranbaloc P, De Frejacques C, Auriol M (1984) Non-transitional cell malignant tumors of the bladder. (springer.com)
  • Deerberg F, Rehm S, Jostmeyer HH (1985) Spontaneous urinary bladder tumors in DA/Han rats: a feasible model of human bladder cancer. (springer.com)
  • Layers of the urinary bladder wall and cross section of the detrusor muscle. (wikipedia.org)
  • Smooth muscle of the bladder (detrusor muscle) is arranged in spiral, longitudinal and circular bundles. (scribd.com)
  • The ureters pass obliquely through the detrusor muscle and it passes little further underneath the bladder mucosa. (scribd.com)
  • Stimulation of parasympathetic efferent fibers causes contraction of detrusor muscle leading to emptying of urinary bladder. (scribd.com)
  • The message sent to the bladder tells the detrusor muscle (the bladder muscle) to contract and expel the urine. (simonfoundation.org)
  • Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. (harvard.edu)
  • The smooth muscle of the bladder is called the detrusor muscle. (histology-world.com)
  • Histology hint from Sarah Bellham: The muscle in the bladder wall is called the detrusor muscle. (histology-world.com)
  • The emptying phase requires the detrusor muscle to contract, forcing urine out of the bladder. (digitalnaturopath.com)
  • Overactive bladder is a common cause, yielding uncontrolled contractions of the detrusor muscle during bladder filling. (digitalnaturopath.com)
  • The concentration-effect relationships of carbachol were studied for three different responses of detrusor muscle of rabbit urinary bladder: the mechanical response, the increase of 45Ca uptake and the displacement of [3H]quinuclidinyl benzilate (QNB) from muscarinic receptors. (aspetjournals.org)
  • 3H]QNB binding was performed on homogenates of rabbit bladder detrusor muscle. (aspetjournals.org)
  • In The Physiology of the Lower Urinary Tract (pp. 161-191). (springer.com)
  • Spontaneous activity of lower urinary tract smooth muscles: correlation between ion channels and tissue function. (springer.com)
  • The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis. (medscape.com)
  • Recommendations on the Use of Botulinum Toxin in the Treatment of Lower Urinary Tract Disorders and Pelvic Floor Dysfunctions: A European Consensus Report. (medscape.com)
  • Sacral Neuromodulation Therapy in Patients with Neurologic Lower Urinary Tract Dysfunction - Should it Remain an Off Label Indication? (medscape.com)
  • In elderly people, the pathophysiological and the physiological change in the lower urinary tract system must be considered as well as an underlying multimorbidity. (urotoday.com)
  • The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. (medscape.com)
  • Most common lower urinary tract symptoms in post-middle aged males are due to benign prostate enlargement. (rainbow.coop)
  • Disturbances in the embryogenesis of the hindgut may result in duplication of the lower urinary tract. (thefreelibrary.com)
  • Urinary incontinence and other lower urinary tract symptoms (LUTS) in women are common, costly, and consequential and are associated with common medical conditions such as obesity, diabetes, and cardiovascular disease. (nih.gov)
  • The NIDDK-sponsored workshop 'Path to Prevention of Lower Urinary Tract Symptoms (LUTS) in Women: Bladder Health' will bring together medical, nursing, physical therapy, patient education, behavior change, epidemiology, public health, and prevention experts in a scientific workshop framed around defining bladder health as a first step along this path. (nih.gov)
  • Methods for obtaining tissue for histopathologic investigation include cystotomy (incision into the bladder), cystoscopy (It is a diagnostic procedure that is used to look at the bladder [lower urinary tract], collect urine samples, and examine the prostate gland) and traumatic catheterization. (wearethecure.org)
  • Mechanical characteristics have a large impact on the functionality of the organs, particularly those in the lower urinary tract, such as the bladder, that are continually subjected to large deformations throughout the physiological cycle. (medicalxpress.com)
  • The three openings, two ureteric orifices , and the internal urethral orifice mark the triangular area called the trigone of the bladder . (wikipedia.org)
  • The middle lobe of the prostate causes an elevation in the mucous membrane behind the internal urethral orifice called the uvula of urinary bladder. (wikipedia.org)
  • The muscularis also forms the internal urethral sphincter, a ring of muscle that surrounds the urethral opening and holds urine in the urinary bladde. (innerbody.com)
  • The pressure within the bladder must be lower than the urethral pressure during the filling phase. (medscape.com)
  • If the bladder pressure is greater than the urethral pressure (resistance), urine will leak out. (medscape.com)
  • Weakness in not just the pelvic floor muscles, but also in the urethral sphincter often plays a role in this type of urinary incontinence. (medicinenet.com)
  • The urethral epithelium is composed of stratified squamous cells, which variably becomes transitional as the bladder is approached. (medscape.com)
  • The medial pubovisceral portion of the levator ani complex also is a major contributor to active bladder neck and urethral closure in similar situations. (medscape.com)
  • A vesical sphincter made up of a thickening of the middle muscular layer of the bladder around the urethral opening. (dictionary.com)
  • These conditions include ectopic ureter, urethral diverticulum, and urinary fistula. (brighamandwomens.org)
  • A lot of care has to be taken while inserting catheter, because the slightest brush may rupture the diseased bladder or the urethral wall. (wearethecure.org)
  • From a holistic standpoint, most bladder control problems that are not the direct result of neurological damage, poor muscle tone or hormone deficiencies are usually the result of irritability within the bladder or urethral tissues caused by chronic inflammation and/or food allergies . (digitalnaturopath.com)
  • WEIGHT LOSS Dropping pounds eases the pressure on your bladder and pelvic floor, says Kristene Whitmore, M.D., chair of urology and female pelvic medicine and reconstructive surgery at Drexel University College of Medicine in Philadelphia. (goodhousekeeping.com)
  • To describe clinical characteristics and assess beliefs and coping strategies in older patients with overactive bladder (OAB) attending urology and gynecology clinics in Spain. (urotoday.com)
  • The urinary bladder is a hollow muscular organ in humans and some other animals that collects and stores urine from the kidneys before disposal by urination . (wikipedia.org)
  • The urinary bladder plays an important role in delaying and controlling urination so that the average person only has to urinate several times each day instead of constantly leaking small amounts of urine. (innerbody.com)
  • The urinary bladder functions as a storage vessel for urine to delay the frequency of urination. (innerbody.com)
  • Frequent urination and nighttime urination often occur with this type of urinary incontinence. (medicinenet.com)
  • Functional incontinence describes untimely urination in people who have normal bladder control but are unable to reach the bathroom in time because of physical disability. (bidmc.org)
  • Benign prostatic hypertrophy (BPH) is a non-cancerous swelling of the prostate resulting in difficulty urinating, reduced urine flow, frequent night urination, and difficulty emptying the bladder. (rainbow.coop)
  • Evaluation for cancer of the urinary bladder is warranted if you have an older dog and notice blood in the urine, increased frequency of urination, and straining to urinate that either does not respond to routine treatment with antibiotics or that resolves only to return after stopping antibiotic treatment. (petplace.com)
  • Bladder stones irritate the lining of the bladder blood in the urine, straining to urinate and increased frequency of urination. (petplace.com)
  • Overactive bladder is a condition characterized by frequent urination during the day or night and a sudden urge to urinate, with or without urinary leakage. (brighamandwomens.org)
  • Veterinarians use these diagnostic tools to look for anything abnormal within the abdomen, but I would be willing to bet that bladder stones (otherwise known as uroliths) are at the top of the rule-out list whenever these tests are ordered for a cat suffering from inappropriate urination. (petmd.com)
  • Part of the ileum (small intestine) is used to make a new bladder, allowing for "normal" urination. (uwhealth.org)
  • These pain impulses cause a sympathetic reflex back to the kidney to constrict the renal arterioles, thereby decreasing urinary output from that kidney. (scribd.com)
  • Maintaining optimal bladder health is integral to keeping your body balanced and assists both kidney and urinary tract health. (mindfood.com)
  • Genesis Today 4Kidney, Bladder & Urinary Health contains pure, all-natural, concentrated cranberry juice, which has been traditionally used to promote healthy kidney and bladder function. (astronutrition.com)
  • At Sky Ridge Medical Center in south metro Denver, our board-certified and subspecialty-trained kidney, urinary and pelvis/reproductive region specialists provide compassionate care from diagnosis through treatment and follow-up. (skyridgemedcenter.com)
  • Evaluates the carcinogenic risk to humans posed by 20 individual compounds and three groups of compounds (cyclamates, saccharin and its salts, and nitrilotriacetic acid and its salts) that are known to induce tumours of the kidney or urinary bladder in rodents. (who.int)
  • Re-evaluations were made in the light of both new studies of the compounds and a growing body of evidence concerning certain pathological processes that lead to tumour development in the kidney and urinary bladder of rats exposed to some chemicals. (who.int)
  • Alkalinizing the urine pH reduces the formation of kidney stones (calcium oxalate bladder stones) that would normally occur due to high levels of calcium or uric acid in the urine. (medi-vet.com)
  • Although UTIs are the second most common condition that GPs are prescribing antibiotics for, in some people, symptoms of a UTI may be masking symptoms of bladder or kidney cancer. (eveningexpress.co.uk)
  • More than 10,500 people are diagnosed with kidney cancer each year in England, while about 8,500 people are diagnosed with bladder cancer. (eveningexpress.co.uk)
  • Of these, about 3,400 are diagnosed with late-stage kidney cancer and 1,800 with late-stage bladder cancer, which lowers the chance of survival. (eveningexpress.co.uk)
  • Urine collects in the bladder, fed from the two ureters that connect the bladder with the kidneys . (wikipedia.org)
  • A pair of ureteral openings on the inferior end of the posterior wall of the urinary bladder allow urine from the left and right ureters to enter the hollow lumen. (innerbody.com)
  • This oblique passage tends to keep the ureters closed except during peristaltic waves, preventing reflux of urine from the bladder. (scribd.com)
  • Errors in the ultrasound diagnosis of the kidneys, ureters and urinary bladder. (springer.com)
  • Urine produced in the kidneys flows into the bladder via the ureters. (histology-world.com)
  • Conventionally clinical and pathological methods are used for the diagnosis and clinical outcome of urinary bladder cancer. (springer.com)
  • An early detection of urinary bladder cancer can be treatable, so it is important to get a diagnosis as soon as you suspect something is wrong. (vetinfo.com)
  • This book presents a complete approach to MR imaging of carcinoma of the urinary bladder from a detailed discussion of the value of MRI in the diagnosis of the urinary bladder to the history of the procedure. (springer.com)
  • Watch your pet closely for changes in urinary habits after diagnosis has been made and treatment begun, because such changes may indicate additional tumor growth. (petplace.com)
  • Differential diagnosis: incomplete duplication of the urinary bladder, urinary bladder diverticulum and cloacal malformation. (thefreelibrary.com)
  • Keeping in mind that overactive bladder and urge incontinence are affected by the functioning of your nerves, it is always important to seek medical diagnosis and treatment: a qualified healthcare professional can run the appropriate tests to rule out any other underlying cause. (simonfoundation.org)
  • Daurat A, Choquet O, Bringuier S, Charbit J, Egan M, Capdevila X. Diagnosis of postoperative urinary retention using a simplified ultrasound bladder measurement. (springer.com)
  • There are various types of urinary incontinence and it is important for the patient to undergo appropriate diagnosis as the treatment of each incontinence type varies significantly. (brighamandwomens.org)
  • A physical examination, laboratory tests, X-ray or Computerized Tomography of the spine, measuring the rest-urine (the urine left in the bladder after urinating) with ultrasound scan might be needed for a complete diagnosis. (ehealthforum.com)
  • See 'Epidemiology and risk factors of urothelial (transitional cell) carcinoma of the bladder' and 'Non-urothelial bladder cancer' . (uptodate.com)
  • Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. (nature.com)
  • Tumor recurrence is a major clinical concern for patients with urothelial carcinoma of the urinary bladder. (nih.gov)
  • Lopez-Beltran A, Requena MJ, Alvarez-Kindelan J, Quintero A, Blanca A, Montironi R. Squamous differentiation in primary urothelial carcinoma of the urinary tract as seen by MAC387 immunohistochemistry. (medscape.com)
  • Carcinoma of the urinary bladder is a common (in the USA it is the fifth most common form of cancer in males and tenth most common form of cancer in females) malignan- cy and one in which noninvasive staging by imaging plays such an important role. (springer.com)
  • The results of the clinical imaging stu- dies in patients with carcinoma of the bladder, comparing the relative value of clinical staging, MR, CT and lymphography, are helpful in showing the advantages of MRI. (springer.com)
  • But invasive transitional cell carcinoma or TCC is the most common type of canine urinary bladder cancer. (wearethecure.org)
  • 1992) Transitional Cell Carcinoma of the Bladder Associated with Crohn's Disease: Case Report and Review of the Literature. (scirp.org)
  • 2003) An Unusual Way to Diagnose a Rare Case of Bladder Carcinoma in a Patient with Crohn's Disease. (scirp.org)
  • Hexaminolevulinate is used to check for cancer cells in the bladder. (mayoclinic.org)
  • Urinary bladder cancer is the most common cancer of urinary tract. (springer.com)
  • The exact etiology of urinary bladder cancer is unknown. (springer.com)
  • Epidemiology and risk factors of urothelial bladder cancer. (springer.com)
  • Impact of gender on bladder cancer incidence, staging, and prognosis. (springer.com)
  • Mechanisms of disease: the epidemiology of bladder cancer. (springer.com)
  • Gender, racial and age differences in bladder cancer incidence and mortality. (springer.com)
  • Gender and geographic influence on the racial disparity in bladder cancer mortality in the US. (springer.com)
  • Ethnic differences in bladder cancer survival. (springer.com)
  • The impact of characteristics of cigarette smoking on urinary tract cancer risk: a meta-analysis of epidemiologic studies. (springer.com)
  • Alcohol drinking and bladder cancer risk: a meta-analysis. (springer.com)
  • Elevated risk of cancer of the urinary tract for alcohol drinkers: a metaanalysis. (springer.com)
  • Pelucchi C, La Vecchia C. Alcohol, coffee, and bladder cancer risk: a review of epidemiological studies. (springer.com)
  • We conducted a genome-wide SNP association study on 1,803 urinary bladder cancer (UBC) cases and 34,336 controls from Iceland and The Netherlands and follow up studies in seven additional case-control groups (2,165 cases and 3,800 controls). (nature.com)
  • Risk of bladder cancer associated with family history of cancer: do low-penetrance polymorphisms account for the increase in risk? (nature.com)
  • Loss of p63 expression is associated with tumor progression in bladder cancer. (nature.com)
  • Urinary bladder cancer in dogs may be frequently met in older dogs, and the precise causes of this condition haven't been determined yet. (vetinfo.com)
  • The bladder cancer should be detected as early as possible, so that the dog has increased chances of survival and several treatment options. (vetinfo.com)
  • The diagnostics of urinary bladder cancer can be done based on the symptoms displayed by the pet and several other clinical tests. (vetinfo.com)
  • Bladder cancer usually has a silent development and there will be no symptoms during the initial stages. (vetinfo.com)
  • If the dog has bladder cancer, he will not respond to this medication and the symptoms will worsen in time. (vetinfo.com)
  • The molecular changes may additionally prove useful for developing preventive and therapeutic strategies for urothelial bladder cancer. (nih.gov)
  • Some patients may in time develop bladder cancer. (medscape.com)
  • Lopez-Beltran A. Bladder cancer: clinical and pathological profile. (medscape.com)
  • Smoking also causes most cases of bladder cancer . (nih.gov)
  • Authors of a meta-analysis question the accuracy of urinary biomarkers for diagnosing the initial incidence or recurrence of bladder cancer. (news-medical.net)
  • Urinary biomarkers miss a substantial proportion of patients with bladder cancer and are subject to false-positive results in others", they write in the Annals of Internal Medicine . (news-medical.net)
  • and fluorescent immunohistochemistry to detect the bladder cancer-specific antigens M344, LDQ10 and 19A211 (ImmunoCyt). (news-medical.net)
  • Urinary biomarkers miss 18% to 43% of patients with bladder cancer and are falsely positive in 12% to 26% of patients without bladder cancer", write Chou et al. (news-medical.net)
  • They conclude: "The value of urinary biomarkers and whether they are sufficiently accurate to reduce the need for cystoscopy depends on the ability of clinicians to estimate the pretest probability of disease, the importance to patients and clinicians of relatively small changes in the probability of bladder cancer, and the acceptable threshold and clinical consequences of missed or delayed diagnoses and false-positive results. (news-medical.net)
  • Currently computed tomography (CT) represents the most widely used standard imaging modality in muscle-invasive urinary bladder cancer. (mdpi.com)
  • Magnetic resonance imaging (MRI) with diffusion-weighted sequences, determination of apparent diffusion coefficient (ADC) values or utilization of superparamagnetic iron nanoparticles potentially exhibits advantages in the assessment of local tumor or lymph node involvement and therefore might play a role in routine staging of urinary bladder cancer in the future. (mdpi.com)
  • Likewise, positron emission tomography (PET) with the currently utilized tracers 18 F-FDG, 11 C-choline and 11 C-acetate is investigated in bladder cancer patients-mostly in combination with diagnostic CT. (mdpi.com)
  • Urinary) bladder cancer (BCa) is considered one of the most common malignancies worldwide with an incidence of 18.5 per 100,000 males and 5.7 per 100,000 females and approximately 25% of newly diagnosed BCa patients present with aggressive muscle-invasive disease [ 1 ]. (mdpi.com)
  • Avoid dipping your dog with flea and tick control products more than two times per year due to possible increased risk of developing bladder cancer. (petplace.com)
  • Other diseases may cause symptoms similar to those of urinary bladder cancer. (petplace.com)
  • Animals with bladder cancer can develop bacterial UTI because the bladder's natural defenses have been damaged, and bladder cancer should be considered in older dogs that have repeated episodes of UTI or UTI that does not respond to appropriate antibiotic treatment. (petplace.com)
  • Diagnostic tests are needed to identify urinary bladder cancer, exclude other diseases and determine the impact of bladder cancer on your pet. (petplace.com)
  • Abdominal and chest X-rays to evaluate for abnormalities of the bladder, enlargement of local lymph nodes and spread of cancer to the lungs. (petplace.com)
  • It is not unusual for bladder cancer to spread to the local lymph nodes in the abdomen. (petplace.com)
  • The UW Prostate and Genitourinary Cancer Program (UWPGCP) and the University of Wisconsin Carbone Cancer Center, the state's only comprehensive cancer center , take a multidisciplinary approach to treating bladder cancer. (uwhealth.org)
  • Description- Urinary bladder cancer accounts for approximately 2% of all reported malignancies in dogs. (wearethecure.org)
  • With more than 60 million dogs in the USA, deaths from urinary bladder cancer are increasing rapidly. (wearethecure.org)
  • Causes- The cause of urinary bladder cancer depends on multiple factors. (wearethecure.org)
  • Treatment - To diagnose bladder cancer a thorough physical examination comprising rectal exam, complete blood count (CBC), serum biochemistry profile, urinanalyis, urine culture, radiography of the thorax and abdomen and bladder imaging (contrast cystography or cystosonography) are essential. (wearethecure.org)
  • Such heavy bleeding is usually due to bladder cancer. (wikipedia.org)
  • NEW YORK (GenomeWeb) - A team of investigators at Oslo University Hospital in Norway has developed a digital PCR-based assay for detecting urinary bladder cancer recurrence that they hope to finalize by year end. (genomeweb.com)
  • There may be differences between incontinence arising from a spinal injury (neurogenic) and that arising from sphincter damage or other issues arising from bladder cancer. (singletrackworld.com)
  • The topic 'Riding advice for a friend with bladder cancer/urinary sheath' is closed to new replies. (singletrackworld.com)
  • Bladder cancer is caused by abnormal cell growth and blood in the urine is one of the first symptoms. (sharecare.com)
  • If urinary solids are the cause of cytotoxicity, the MOA is not relevant to human cancer, but dose response becomes essential for evaluating potential toxicity to humans. (rsc.org)
  • Based on this process, a screen for urinary bladder carcinogenicity is reliable, and more importantly, can be based on MOA and dose response analyses useful in the overall risk assessment for possible human bladder cancer. (rsc.org)
  • Birt DF, Julius AD, Hasegawa R, St. John M, Cohen SM (1987) Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion. (springer.com)
  • Cohen SM (1983) Pathology of experimental bladder cancer in rodents. (springer.com)
  • In: Bryan GT, Cohen SM (eds) The pathology of bladder cancer, vol 2. (springer.com)
  • EI-Bolkainy MN (1983) Schistosomiasis and bladder cancer. (springer.com)
  • The renal ultrasound (Figure 1) revealed a vascular solid mass in the anterior wall of the urinary bladder, slightly to the left of the midline, measuring 3.4 cm transverse by 2.8 cm anteroposterior by 3.9 cm craniocaudal. (appliedradiology.com)
  • A common part of the medical work-up for a cat that has urinary symptoms (e.g., urinating outside of the litter box, straining to urinate, etc.) is an abdominal X-ray and/or ultrasound. (petmd.com)
  • Today we'll take a look at treatment options available for cats when the X-rays or ultrasound have confirmed the presence of bladder stones. (petmd.com)
  • The ultrasound showed an increased wall thickness of the small bowel and cecum and a vegetating lesion adjoined into the bladder. (scirp.org)
  • Play media Ultrasound showing bladder rupture - Week 1 Play media Ultrasound showing bladder rupture - Week 2 Bladder tamponade is obstruction of the bladder outlet due to heavy blood clot formation within it. (wikipedia.org)
  • This medicine is given through a tube (catheter) that is placed in your bladder. (mayoclinic.org)
  • Jamison J, Maguire S, McCann J. Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders. (medscape.com)
  • Measured and Modeled Effects of Suprapubic Catheter Size on Urinary Flow. (medscape.com)
  • This topic will discuss the complications associated with urinary catheter use. (uptodate.com)
  • It is helpful to measure the size of the bladder or the degree of urinary retention, assess presence or absence of a significant mass, confirm the position of a bladder catheter, and guide suprapubic catheter placement. (springer.com)
  • A catheter will be in place to allow the urinary tract to rest and to drain the urine. (portsmouthhospital.com)
  • This is done by instilling 4-8 ml/kg of sterile saline into the bladder through a urinary catheter. (wearethecure.org)
  • This inflammation of urinary bladder is highly chronic and leads to urgent and frequent need to urinate. (articlealley.com)
  • Women should try to relax the muscles around their bladder when they urinate to make it easier to go. (nih.gov)
  • Take as much time as needed to urinate and empty your whole bladder. (nih.gov)
  • Overactive bladder and urge urinary incontinence result in the need to go to the bathroom frequently, waking up at night to void, feeling strong urges to urinate or the inability to get to the toilet on time. (bidmc.org)
  • Inability to urinate leads to severe metabolic complications called uremia within less than three days of complete urinary obstruction. (petplace.com)
  • Overactive bladder (OAB) is a condition in which the bladder can spasm and cause a sudden, intense and frequent urge to urinate. (simonfoundation.org)
  • As the bladder fills, the nerves sense the fullness and send a signal to your brain telling you that you need to urinate. (simonfoundation.org)
  • When you are at the toilet, your brain will send the message to your bladder that it is now appropriate to urinate. (simonfoundation.org)
  • When you have OAB, the nerves alert you that you need to urinate, but your ability to inhibit this urge is compromised and then the bladder starts to spasm on its own and push the urine out. (simonfoundation.org)
  • Some people have overactive bladder without any incontinence - they simply feel frequent and intense urges to urinate, but always make it to the bathroom in time. (simonfoundation.org)
  • Overactive bladder, also called urge incontinence, is caused by urinary muscle spasms that cause an urgency to urinate. (boots.com)
  • Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. (harvard.edu)
  • Generally, a person feels like they need to urinate when approximately 200 ml of urine fills up in the bladder. (digitalnaturopath.com)
  • People with acute urinary retention cannot urinate at all, even though they have a full bladder. (empowher.com)
  • People with chronic urinary retention can urinate. (empowher.com)
  • According to the data you provided (urge to urinate that disappears after quickly getting up and walking and then returns after several minutes, back injury that turned into slip disk), you might be experiencing overly frequent and strong peristaltic contractions of the bladder muscle responsible for expelling the urine. (ehealthforum.com)
  • Surgical management of functional bladder outlet obstruction in adults with neurogenic bladder dysfunction. (medscape.com)
  • These can partially or completely lead to the obstruction of urinary tract in dogs. (wearethecure.org)
  • The wall of the urinary bladder is normally 3-5 mm thick. (wikipedia.org)
  • Sensory fibers in the pelvic nerve carry impulses from stretch receptors present on the wall of the urinary bladder to the spinal centre of micturition. (scribd.com)
  • Symptoms- In dogs diagnosed with TCC, the wall of the urinary bladder is found to be thickened. (wearethecure.org)
  • Stress incontinence and overactive bladder (OAB) are the main causes of incontinence. (boots.com)
  • Transobturator vaginal tape for the treatment of stress urinary incontinence in elderly women without concomitant pelvic organ prolapse: is it effective and safe? (medscape.com)
  • We report a very rare case of intra-peritoneal spontaneous rupture of the urinary bladder which was successfully managed conservatively in a 77-year-old woman, who presented with lower abdominal pain, acute urinary retention and pelvic organ prolapse (POP). (biomedsearch.com)
  • Lymphomas of the urinary bladder have a female predominance, and most cases of lymphoma of the urinary bladder occur in middle-age women [ 1 ]. (hindawi.com)
  • Secondary involvement of the urinary bladder occurs in 10% to 25% of leukemias/lymphomas and they occur in advanced-stage systemic lymphoma [ 1 ]. (hindawi.com)
  • VUR can occur through a defective ureterovesical junction (UVJ) or an overwhelmed normal UVJ mechanism such as in bladder dysfunction of congenital, acquired, or behavioral etiology. (urotoday.com)
  • These conditions occur when nerve passages along the pathway from the bladder to the brain are damaged, causing a sudden bladder contraction that cannot be consciously inhibited. (bidmc.org)
  • It can be caused by injury to the urinary tract, which can occur accidentally during surgery, be caused by a tumor, or be due to tissue death (necrosis) caused by radiation therapy or by reduced blood supply from prolonged labor during childbirth. (bidmc.org)
  • Duplication of the urinary bladder may occur in the sagittal or coronal plane. (thefreelibrary.com)
  • Duplication may occur in the sagittal (more common) or coronal planes, with the corresponding ipsilateral ureter draining each half of the urinary bladder. (thefreelibrary.com)
  • Bladder rupture (rupture of bladder, N32.4) may occur if the bladder is overfilled and not emptied. (wikipedia.org)
  • Undesired bladder muscle contractions may occur from nervous system (neurological) problems and bladder irritation. (digitalnaturopath.com)
  • Anatomic incontinence typically occurs early in life or after surgical intervention and is due to abnormal anatomy resulting in urinary leakage. (brighamandwomens.org)
  • In gross anatomy, the bladder can be divided into a broad fundus, a body, an apex, and a neck. (wikipedia.org)
  • Linguistic Validation of the Intermittent Self-catheterization Questionnaire for Patients With Neurogenic Bladder Who Perform Intermittent Catheterization for Voiding Dysfunction. (urotoday.com)
  • Her clinical practice involves the evaluation and treatment of women with urinary incontinence, voiding dysfunction, and pelvic floor disorders. (simonfoundation.org)
  • Symptoms associated with dysfunction of the bladder are highly prevalent which deeply impair the quality of life of peoples, resulting in socio-economic burden on society. (thefreelibrary.com)
  • A urine test can give some hints about the presence of a tumor or cancerous cells in the urinary bladder. (vetinfo.com)
  • After the tumor is identified in the dog's bladder area, the vet will have to perform a biopsy of the cells. (vetinfo.com)
  • Molecular determinants of tumor recurrence in the urinary bladder. (nih.gov)
  • However, molecular and genetic analyses offer new perspectives on the prediction of bladder tumor recurrence. (nih.gov)
  • Occasionally, bladder tumor cells can be identified by microscopic examination of the urine. (petplace.com)
  • To avoid the risk of tumor seeding (spillage of tumor cell clusters and their subsequent growth at a site adjacent to the original tumor) through cystosyntesis (a procedure in which needle is inserted into the urinary bladder of an animal through the abdomen and a sample of urine is removed), urine may be collected by free catch or catheterization. (wearethecure.org)
  • Chin NW, Marinescu AM, Fani KF (1992) Composite adenocarcinoma and carcinoid tumor of urinary bladder. (springer.com)
  • What how frequently should the bladder be drained with intermittent catheterization for urinary incontinence? (medscape.com)
  • Treatment includes physical therapy, neuromodulation, and urinary catheterization. (brighamandwomens.org)
  • Treatment may be a bedside commode or urinary catheterization. (brighamandwomens.org)
  • We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests. (urotoday.com)
  • The aim of this review is to update the indications, contraindications, technique, complications, and the tissue engineering approaches of augmentation cystoplasty (AC) in patients with neurogenic bladder. (urotoday.com)
  • Surgery on the bladder is not all that difficult, but it does carry risks associated with general anesthesia, leaving stones behind, surgical complications, etc. (petmd.com)
  • This might be the first symptoms of more serious condition, so you are advised to visit a neurologist for the bladder problem and the slip disk in order to cure it and prevent possible complications. (ehealthforum.com)
  • Nonsurgical management of urinary incontinence in women: a clinical practice guideline from the American College of Physicians. (medscape.com)
  • Botulinum toxin (OnabotulinumtoxinA) in the male non-neurogenic overactive bladder: clinical and quality of life outcomes. (urotoday.com)
  • Clinical characteristics, beliefs, and coping strategies among older patients with overactive bladder. (urotoday.com)
  • Clinical outcomes of non-surgical management of detrusor leak point pressures above 40 cm water in adults with congenital neurogenic bladder. (urotoday.com)
  • Management of urinary incontinence in postmenopausal women: An EMAS clinical guide. (medscape.com)
  • She has extensive experience in clinical research for the treatment of women with stress urinary incontinence, detrusor overactivity and genital prolapse. (simonfoundation.org)
  • Elterman DS, Chughtai B, Vertosick E, Thomas D, Eastham J, Sandhu J. Trends and Clinical Practice Patterns of Sacral Neuromodulation for Overactive Bladder. (harvard.edu)
  • These observations are in keeping with the clinical finding that a bladder cooling reflex can be elicited in patients with disturbed descending control of the bladder. (diva-portal.org)
  • This increase in the pressure initiates a peristaltic contraction beginning in the pelvis and spreading downward along the ureter to force urine toward the bladder. (scribd.com)
  • In some people, the distance that the ureter courses through the bladder mucosa is less than normal, so that contraction of the bladder during micturition does not always lead to complete occlusion of the ureter. (scribd.com)
  • As a result some of the urine in the bladder is propelled backward into the ureter. (scribd.com)
  • Upon examining the histology, it can be seen that the bladder wall has the same tissue layers as the renal pelvis and ureter. (histology-world.com)
  • These disorders affect both men and women and range from overactive and underactive bladder, to urinary incontinence , to bladder outlet obstructions. (medicalxpress.com)
  • You may also visit our Urinary and Bladder Disorders , for moderated patient to patient support and information. (ehealthforum.com)
  • and high-acid foods such as citrus and tomatoes may contribute to bladder irritation and inflammation , which can sometimes lead to UI. (nih.gov)
  • Women suffer predominantly from stress and mixed urinary incontinence and men from urge incontinence. (urotoday.com)
  • The visceral muscles of the muscularis layer surround the submucosa and provide the urinary bladder with its ability to expand and contract. (innerbody.com)
  • Certain smooth muscles, such as the detrusor of the urinary bladder, exhibit a variety of spikes that differ markedly in their amplitudes and time courses. (springer.com)
  • The leaks have stopped, thanks to a class aimed at strengthening her pelvic floor - the hammock of muscles that supports the internal organs, including the bladder, bowels, and uterus. (goodhousekeeping.com)
  • However, regularly holding urine in can wear out your bladder muscles. (nih.gov)
  • Hovering over a toilet seat to avoid touching it does not allow muscles to fully relax and may result in urine being left in the bladder. (nih.gov)
  • Your pelvic floor muscles help hold urine in the bladder. (nih.gov)
  • The bladder is a muscle, and like all muscles it is controlled by nerves. (simonfoundation.org)
  • Over time, the sensation to void is reduced and the muscles of the bladder wall become injured leading to more relaxation and worsening of symptoms. (adventisthealth.org)
  • A large loss of urine is often experienced as the muscles of the bladder wall start to spasm or contract. (adventisthealth.org)
  • Baharya Pranayama particularly addresses the problems of weak uterine and urinary bladder muscles. (empowher.com)
  • Iv tried really relaxing my bladder muscles and being relaxed all the time but that hasnt worked. (ehealthforum.com)
  • Hearing running water or changing position may trigger bladder contractions and lead to urine loss. (medicinenet.com)
  • The other is a loss of the nervous system's inhibitory control of bladder contractions. (medicinenet.com)
  • Overactive bladder contractions that send you running to the bathroom quite frequently, without any leakage is referred to as "UUI-dry. (simonfoundation.org)
  • These contractions may cause urge urinary incontinence, urgency and frequency. (digitalnaturopath.com)
  • In isolated rabbit urinary bladder preparations, Artemisia vulgaris (Av.Cr) crude extract inhibited the contractions produced by carbachol (CCh, 1 M) and high K+ (80 mM) in a concentration-dependent (0.03-10 mg/mL) manners. (thefreelibrary.com)
  • Contractions induced by low K+ were partially antagonized by glibenclamide (3 M). These results indicate that urinary bladder relaxation produced by Artemisia vulgaris extract is mediated via dual, anticholinergic and Ca++ antagonist mechanisms, while that of Aspalathus linaris via dominant KATP channel opening and weak Ca++ channel blockade pathways. (thefreelibrary.com)
  • All of these symptoms are usually experienced by patients during filling phase of micturition cycle due to involuntary contractions of the bladder. (thefreelibrary.com)
  • When tested in urinary bladder strips, Av.Cr relaxed the contractions produced by K+ (80 mM) and CCh (1 M) (Figure 1), resulting with EC50 values of 0.26 (0.14-0.5, 95% CI, n=4) and 3.4 mg/mL (2.5-4.9, n=4) respectively. (thefreelibrary.com)
  • Further filling of the bladder with urine additionally extends the muscle and its contractions become more frequent. (ehealthforum.com)
  • Multicenter Randomized Controlled Trial of Bacterial Interference for Prevention of Urinary Tract Infectionin Patients With Neurogenic Bladder. (medscape.com)
  • Assessment of Proportion of Hidden Patients Having Symptoms of Overactive Bladder and Why Has It Been Hidden in Female Outpatients Admitted to Hospital. (urotoday.com)
  • To determine the proportion of patients with undetected symptoms of overactive bladder by using the overactive bladder-validated 8 (OAB-V8) screening questionnaire and investigate these symptoms were undetected in female patients who were hospitalized. (urotoday.com)
  • Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients. (urotoday.com)
  • Prospective evaluation of mouth and eye dryness induced by antimuscarinic drugs used for neurogenic overactive bladder in 35 patients with multiple sclerosis]. (urotoday.com)
  • Mouth and eye dryness are frequently reported by patients with multiple sclerosis (MS) as side effects of antimuscarinic drugs used for neurogenic overactive bladder. (urotoday.com)
  • To assess the correlation between the anorectal function and bladder detrusor function in patients with complete spinal cord injury (SCI) according to the type of lesion. (urotoday.com)
  • We report the findings from a subset of patients in a randomized control trial of transcutaneous tibial nerve stimulation (TTNS) for bladder neuromodulation in acute spinal cord injury (SCI) in whom heart rate variability (HRV) was recorded before and after cystometrogram (CMG). (urotoday.com)
  • Early postnatal bladder function in fetoscopic myelomeningocele repair patients. (urotoday.com)
  • The purpose of this study was to review early postnatal bladder function in patients undergoing a novel endoscopic approach for MMC repair using an exteriorized uterus. (urotoday.com)
  • It's especially beneficial for patients with overactive bladder. (bidmc.org)
  • Approximately 90 percent of all patients experiencing urinary incontinence will have urge incontinence also known as overactive bladder (OAB), stress incontinence, or mixed incontinence. (brighamandwomens.org)
  • Lymphoma of the urinary bladder (LUB) is rare. (hindawi.com)
  • The ensuing document contains a review of the literature on lymphoma of the urinary bladder. (hindawi.com)
  • Documentations from 46 sources were found which had discussed various aspects relevant to lymphoma of the urinary bladder and information from these 46 sources were used to write the literature review. (hindawi.com)
  • Lymphoma of the urinary bladder can be either (a) primary lymphoma of the urinary bladder and this is a rare lymphoma originating in the urinary bladder with no known lymphoma elsewhere or (b) secondary lymphoma of the urinary bladder and this is much more common, and this secondary lymphoma is associated with a primary lymphoma originating in an extra vesical site [ 1 ]. (hindawi.com)
  • Less than 100 cases of lymphoma of the urinary bladder have been reported so far [ 1 ]. (hindawi.com)
  • Lymphoma of the urinary bladder presents with visible haematuria, dysuria, urinary frequency, nocturia, and abdominal pain or back pain [ 1 ]. (hindawi.com)
  • Primary malignant lymphoma of the urinary bladder is very rare. (nih.gov)
  • We report a case of primary T-cell lymphoma of the urinary bladder in a patient with a history of schistosomiasis. (nih.gov)
  • Posted in Types of Incontinence and tagged OAB , overactive bladder , overactive bladder medications , overactive bladder treatments , urge incontinence , urge urinary incontinence , UUI . (simonfoundation.org)
  • Stress urinary incontinence is one of the most common types of incontinence and is characterized by urinary leakage during physical activities including coughing, sneezing, exercising, lifting, and laughing. (brighamandwomens.org)
  • To address the condition of urinary incontinence (UI), I will outline the types of incontinence and testing that are available to assess this wide-scaled problem and preview solutions that range from simple changes in behavior to mediations and or surgery as appropriate. (adventisthealth.org)
  • Apparatus and method for suprapubic drainage of the urinary bladder comprises a small trocar for puncturing the bladder wall following which a flexible drainage tube is inserted through the lumen of the trocar and into the bladder. (freepatentsonline.com)
  • In accordance with the foregoing objects, there is provided an apparatus, which may be in kit form, that includes a small diameter trocar or like cannulated needle for puncturing the bladder wall, and a small diameter flexible drainage tube insertable at one end through the lumen of the cannula and into the bladder. (freepatentsonline.com)
  • Diagnostic Tool for Assessing Overactive Bladder Symptoms: Could the International Prostate Symptom Storage Subscore Replace the Overactive Bladder Symptom Score? (urotoday.com)
  • [3] In males the neck of the urinary bladder is adjacent to the prostate gland . (wikipedia.org)
  • Most cases arise in the dome, the lateral or posterior walls, or the bladder neck. (medscape.com)
  • Surgical therapy for female stress urinary incontinence (SUI) includes bladder neck slings, midurethral slings, and Burch urethropexy ( table 1 ). (uptodate.com)
  • This topic reviews bladder neck (also known as suburethral or pubovaginal) fascial sling procedures. (uptodate.com)
  • In women undergoing surgical treatment, midurethral synthetic slings are generally preferred to bladder neck fascial slings or Burch urethropexy [ 3 ]. (uptodate.com)
  • However, in women who decline or are not candidates for midurethral slings, bladder neck autologous fascial slings remain an effective treatment for SUI. (uptodate.com)
  • This condition is due to an anatomic weakness of the bladder neck which typically maintains the seal of urine during activity. (brighamandwomens.org)
  • Rabbit urinary bladder tissues: From rabbit whose neck was cervically dislocated, urinary bladder was isolated and sectioned into four vertical strips (Gilani et al. (thefreelibrary.com)
  • Schematic of the anatomical regions of the human urinary bladder. (medicalxpress.com)
  • My proposal describes a multi-step short-term (90 day) screening process that characterizes known human urinary bladder carcinogens, and identifies those reported in rodent two-year bioassays. (rsc.org)
  • Urge urinary incontinence is one of the most disturbing symptoms of overactive bladder and is characterized by a strong desire to void that is associated with an involuntary loss of urine. (digitalnaturopath.com)
  • That said, if your cat needs surgery to remove calcium oxalate bladder stones, you really don't have any other widely-available options, so go ahead and schedule it. (petmd.com)
  • Comparison of cardiovascular events among treatments for overactive bladder: a Danish nationwide cohort study. (urotoday.com)
  • Primary treatments for overactive bladder include behavioral interventions and medications. (brighamandwomens.org)
  • The histology was not suggestive of CD and it excluded the bladder neoplasm. (scirp.org)
  • When looking at a histology slide of the bladder mucosa, the transitional epithelium has domed shaped cells on the apical surface. (histology-world.com)
  • When examinging a histology slide of the bladder, a well delineated submucosa is not visible. (histology-world.com)
  • When looking at a histology slide of the bladder, uUnderneath the mucosa of the bladder is a layer called the muscularis. (histology-world.com)
  • Histology hint from Sarah Bellham: You may come across these other words to describe the histology of the bladder. (histology-world.com)
  • Erttirk E, Cohen SM, Price JM, Bryan GT (1969) Pathogenesis, histology, and transplant ability of urinary bladder carcinomas induced in albino rats by oral administration of N-[4-(5-nitro-2furyl)-2-thiazolyl] formamide. (springer.com)
  • In humans, the bladder is a hollow muscular organ situated at the base of the pelvis . (wikipedia.org)
  • The adventitia loosely connects the urinary bladder to the surrounding tissues of the pelvis. (innerbody.com)
  • Computed tomography scan of the pelvis showed a large lobular mass occupying the urinary bladder. (nih.gov)
  • What kind of urinary incontinence do I have? (familydoctor.org)
  • The hallmark symptom of this kind of urinary incontinence is a sudden, overwhelming urge to void, accompanied by loss of urine. (medicinenet.com)
  • Squamous papilloma is a rare benign neoplasm seen in the bladder. (medscape.com)
  • This case represents, to our knowledge, a very rare primary lymphoproliferative neoplasm of the urinary bladder that might represent an unusual immune response to schistosomiasis. (nih.gov)
  • OBJECTIVE: To assess the efficacy of OnabotulinumtoxinA (BTXA) injections in men with drug-refractory non-neurogenic overactive bladder (NNOAB). (urotoday.com)
  • Augmentation cystoplasty in neurogenic bladder. (urotoday.com)
  • Aim: Percutaneous tibial nerve stimulation is used to decrease incontinence in chronic neurogenic bladder. (urotoday.com)
  • Management of vesicoureteral reflux in neurogenic bladder. (urotoday.com)
  • Safety, Feasibility, and Efficacy of Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury Neurogenic Bladder: A Randomized Control Pilot Trial. (urotoday.com)
  • As a result, the quantity of urine in the bladder exceeds the bladder's holding capacity, causing unexpectedly leaking or overflowing. (bidmc.org)
  • The innermost layer of the bladder is the mucosa layer that lines the hollow lumen. (innerbody.com)
  • In all other regions of the bladder, the outer layer of the bladder is adventita. (histology-world.com)
  • Help support urinary tract and bladder health with these simple tips. (mindfood.com)
  • I'm pleased to let you know there are things you can do to help your pet maintain optimal urinary tract and bladder health. (mercola.com)
  • The assessment is attempting to detect whether vesicoureteral reflux (VUR), the backward flow of urine from the bladder to the kidneys, is present. (sciencephoto.com)
  • Unlike the mucosa of other hollow organs, the urinary bladder is lined with transitional epithelial tissue that is able to stretch significantly to accommodate large volumes of urine. (innerbody.com)
  • Recent studies have suggested that urothelial carcinogenesis occurs as a 'field effect' that can involve any number of sites in the bladder mucosa. (nih.gov)
  • The innermost portion of the urinary bladder is the mucosa. (histology-world.com)