A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
Tumors or cancer of the URINARY BLADDER.
Pathological processes of the URINARY BLADDER.
Stones in the URINARY BLADDER; also known as vesical calculi, bladder stones, or cystoliths.
The epithelial lining of the URINARY TRACT.
A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.
Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.
Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.
Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. This is often associated with SPINAL CORD DISEASES, but may also be caused by BRAIN DISEASES or PERIPHERAL NERVE DISEASES.
A substituted carcinogenic nitrosamine.
Discharge of URINE, liquid waste processed by the KIDNEY, from the body.
The duct which coveys URINE from the pelvis of the KIDNEY through the URETERS, BLADDER, and URETHRA.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
Endoscopic examination, therapy or surgery of the urinary bladder.
Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.
Passage of a CATHETER into the URINARY BLADDER or kidney.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Inability to empty the URINARY BLADDER with voiding (URINATION).
Used for excision of the urinary bladder.
The mechanical laws of fluid dynamics as they apply to urine transport.
A species of the true toads, Bufonidae, becoming fairly common in the southern United States and almost pantropical. The secretions from the skin glands of this species are very toxic to animals.
The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.
Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.
Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
Presence of blood in the urine.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
An abnormal passage in the URINARY BLADDER or between the bladder and any surrounding organ.
Temporary or permanent diversion of the flow of urine through the ureter away from the URINARY BLADDER in the presence of a bladder disease or after cystectomy. There is a variety of techniques: direct anastomosis of ureter and bowel, cutaneous ureterostomy, ileal, jejunal or colon conduit, ureterosigmoidostomy, etc. (From Campbell's Urology, 6th ed, p2654)
A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
A birth defect in which the URINARY BLADDER is malformed and exposed, inside out, and protruded through the ABDOMINAL WALL. It is caused by closure defects involving the top front surface of the bladder, as well as the lower abdominal wall; SKIN; MUSCLES; and the pubic bone.
Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
An arsenical that has been used as a dermatologic agent and as an herbicide.
Flavoring agent and non-nutritive sweetener.
Partial or complete blockage in any part of the URETHRA that can lead to difficulty or inability to empty the URINARY BLADDER. It is characterized by an enlarged, often damaged, bladder with frequent urges to void.
A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
Surgical creation of an opening (stoma) in the URINARY BLADDER for drainage.
Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.
A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOOTH MUSCLES.
Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER.
Pathological processes of the URINARY TRACT in both males and females.
A uroplakin subtype that heterodimerizes with UROPLAKIN IB to form a component of the asymmetric unit membrane found in urothelial cells.
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Examination of urine by chemical, physical, or microscopic means. Routine urinalysis usually includes performing chemical screening tests, determining specific gravity, observing any unusual color or odor, screening for bacteriuria, and examining the sediment microscopically.
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
A uroplakin subtype that heterodimerizes with UROPLAKIN IA to form a component of the asymmetric unit membrane found in urothelial cells.
Surgery performed on the urinary tract or its parts in the male or female. For surgery of the male genitalia, UROLOGIC SURGICAL PROCEDURES, MALE is available.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
The combination of two or more different factors in the production of cancer.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.
The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.
A complex network of nerve fibers in the pelvic region. The hypogastric plexus distributes sympathetic fibers from the lumbar paravertebral ganglia and the aortic plexus, parasympathetic fibers from the pelvic nerve, and visceral afferents. The bilateral pelvic plexus is in its lateral extent.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.
Elements of limited time intervals, contributing to particular results or situations.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Use of electric potential or currents to elicit biological responses.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Structures which collect and store urine and are emptied by catheterization of a cutaneous stoma or internal diversion to the urethra. The reservoirs are surgically created during procedures for urinary diversion.
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist.
An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.
Involuntary discharge of URINE that is associated with an abrupt and strong desire to void. It is usually related to the involuntary contractions of the detrusor muscle of the bladder (detrusor hyperreflexia or detrusor instability).
Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.
Methods and procedures for the diagnosis of diseases or dysfunction of the urinary tract or its organs or demonstration of its physiological processes.
Radiography of any part of the urinary tract.
Abnormal enlargement or swelling of a KIDNEY due to dilation of the KIDNEY CALICES and the KIDNEY PELVIS. It is often associated with obstruction of the URETER or chronic kidney diseases that prevents normal drainage of urine into the URINARY BLADDER.
An embryonic structure originating from the ALLANTOIS. It is a canal connecting the fetal URINARY BLADDER and the UMBILICUS. It is normally converted into a fibrous cord postnatally. When the canal fails to be filled and remains open (patent urachus), urine leaks through the umbilicus.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.
A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.
The family of true toads belonging to the order Anura. The genera include Bufo, Ansonia, Nectophrynoides, and Atelopus.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
An abnormal passage in any part of the URINARY TRACT between itself or with other organs.
The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.
One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)
Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.
A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Cell surface proteins that bind PURINES with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized classes of purinergic receptors in mammals are the P1 receptors, which prefer ADENOSINE, and the P2 receptors, which prefer ATP or ADP.
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
A nonapeptide that contains the ring of OXYTOCIN and the side chain of ARG-VASOPRESSIN with the latter determining the specific recognition of hormone receptors. Vasotocin is the non-mammalian vasopressin-like hormone or antidiuretic hormone regulating water and salt metabolism.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.
Contractions of the abdominal muscles upon stimulation of the skin (superficial abdominal reflex) or tapping neighboring bony structures (deep abdominal reflex). The superficial reflex may be weak or absent, for example, after a stroke, a sign of upper (suprasegmental) motor neuron lesions. (Stedman, 25th ed & Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p1073)
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Painful URINATION. It is often associated with infections of the lower URINARY TRACT.
Tumors or cancer of the URINARY TRACT in either the male or the female.
The killing of animals for reasons of mercy, to control disease transmission or maintain the health of animal populations, or for experimental purposes (ANIMAL EXPERIMENTATION).
Compounds that bind to and activate ADRENERGIC BETA-3 RECEPTORS.
Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.
That phase of a muscle twitch during which a muscle returns to a resting position.
Organic chemicals which have two amino groups in an aliphatic chain.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
A non-hydrolyzed muscarinic agonist used as a research tool.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.
Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DISEASES.
The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
Properties, functions, and processes of the URINARY TRACT as a whole or of any of its parts.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.
A plant genus of the family DENNSTAEDTIACEAE. Members contain ptaquiloside, braxin A1, and braxin B. The name is similar to brake fern (PTERIS).
Neurons which send impulses peripherally to activate muscles or secretory cells.
An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
Surgical incision or puncture into a URINARY BLADDER. Cystotomy may be used to remove URINARY CALCULI, or to perform tissue repair and reconstruction.
A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.
An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE.
A subclass of purinergic P2 receptors that signal by means of a ligand-gated ion channel. They are comprised of three P2X subunits which can be identical (homotrimeric form) or dissimilar (heterotrimeric form).
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Cancer or tumors of the URETHRA. Benign epithelial tumors of the urethra usually consist of squamous and transitional cells. Primary urethral carcinomas are rare and typically of squamous cells. Urethral carcinoma is the only urological malignancy that is more common in females than in males.
Pathological processes involving the URETHRA.
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
A thin lining of closed cavities of the body, consisting of a single layer of squamous epithelial cells (MESOTHELIUM) resting on a thin layer of CONNECTIVE TISSUE, and covered with secreted clear fluid from blood and lymph vessels. Major serous membranes in the body include PERICARDIUM; PERITONEUM; and PLEURA.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Catheters inserted into the URINARY BLADDER or kidney for therapeutic or diagnostic purposes.
Drugs that bind to and activate cholinergic receptors.

Obstructive uropathy and hydronephrosis in male KK-Ay mice: a report of cases. (1/3541)

Uropathy associated with hydronephrosis was observed frequently in our male KK-Ay mouse colony during a long-term study of diabetes. The lesion occurred in 24 of the 31 KK-Ay male mice and accounted for the greatest number of spontaneous deaths among them. It was observed after 4 months of age and involved about hard plugs of altered seminal material resembling the seminal vesicle secretion. The plugs became impacted in the urethral bulb and the bladder. The penile anatomy, with its flexure, pressure on the urethra from the bulbocavernosus muscle, and the characteristic ability of the seminal fluid to easily coagulate to form the vaginal plug may have contributed to the lesion. Correlation between development of the uropathy and diabetes has not been established.  (+info)

Evidence for beta3-adrenoceptor subtypes in relaxation of the human urinary bladder detrusor: analysis by molecular biological and pharmacological methods. (2/3541)

The purpose of the present study was to confirm the presence of beta3-adrenoceptor subtype in the relaxation of human urinary bladder detrusor tissue by reverse transcription-polymerase chain reaction (PCR); direct sequencing of the PCR product, in situ hybridization; and isometric contraction. Using reverse transcription-PCR, the mRNAs of three receptor subtypes (beta1, beta2, and beta3) were expressed in the human urinary bladder detrusor tissue. Direct sequencing of the PCR product of the above beta3-adrenoceptor revealed no mutation in the amplified regions. In situ hybridization with digoxygenin-labeled oligonucleotide probe revealed the presence of the mRNA of beta3-adrenoceptor subtype in the smooth muscle of the urinary bladder. The relaxant effects of isoproterenol (a nonselective beta-adrenoceptor agonist); ZD7114, BRL37344, and CGP12177A (putative selective beta3-adrenoceptor agonists); and SR59230A (a putative selective beta3-adrenoceptor antagonist) were tested using an isometric contraction technique. Isoproterenol in either the presence or absence of both atenolol (a beta1-adrenoceptor-selective antagonist) and butoxamine (a beta2-adrenoceptor-selective antagonist) revealed a relaxant effect on the carbachol-induced contraction of the human urinary bladder detrusor. Both BRL37344 and CGP12177A also revealed relaxant effects on the human urinary bladder detrusor, but ZD7114 did not elicit any relaxation. These results suggest that beta3-adrenoceptor may have some role in urine storage in the human urinary bladder.  (+info)

Adrenoreceptors of the guinea-pig urinary bladder. (3/3541)

1 Adrenaline, noradrenaline and isoprenaline (5 mug/ml) did not affect the resting tone of the isolated urinary bladder of the guinea-pig. 2 The catecholamines (1-2 mug/ml) inhibited neuronally evoked contractions at various stimulation frequencies; the inhibition was maximum at 2 Hz and minimum at 50 Hz. Isoprenaline produced maximum inhibition. 3 Propranolol (0.5 mug/ml) completely blocked the catecholamine-induced inhibition at all the frequencies employed. The concentration-response curves of isoprenaline at 2, 10 and 50 Hz were characteristically shifted by propranolol (50 ng/ml). Phenoxybenzamine (0.2 mug/ml) was totally ineffective. 4 In some experiments adrenaline significantly raised the tone of the bladder exposed to propranolol; this effect could be blocked by phenoxybenzamine. 5 Acetylcholine-induced bladder contractions were inhibited by adrenaline (2 mug/ml); the inhibition was completely blocked by propranolol (0.5 mug/ml). 6 The results indicate the presence of an inhibitory beta-adrenoceptor and suggest the possibility of an excitatory alpha-adrenoceptor in guinea-pig urinary bladder.  (+info)

M2 receptors in genito-urinary smooth muscle pathology. (4/3541)

In vitro bladder contractions in response to cumulative carbachol doses were measured in the presence of selective muscarinic antagonists from rats which had their major pelvic ganglion bilaterally removed (denervation, DEN) or from rats in which the spinal cord was injured (SCI) via compression. DEN induced both hypertrophy (505+/-51 mg bladder weight) and a supersensitivity of the bladders to carbachol (EC50=0.7+/-0.1 uM). Some of the SCI rats regained the ability to void spontaneously (SPV). The bladders of these animals weighed 184+/-17 mg, significantly less than the bladders of non voiding rats (NV, 644+/-92 mg). The potency of carbachol was greater in bladder strips from NV SCI animals (EC50=0.54+/-0.1 uM) than either bladder strips from SPV SCI (EC50=0.93+/-0.3 microM), DEN or control (EC50=1.2+/-0.1 microM) animals. Antagonist affinities in control bladders for antagonism of carbachol induced contractions were consistent with M3 mediated contractions. Antagonist affinities in DEN bladders for 4-diphenlacetoxy-N-methylpiperidine methiodide (4-DAMP, 8.5) and para fluoro hexahydrosilodifenidol (p-F-HHSiD, 6.6); were consistent with M2 mediated contractions, although the methoctramine affinity (6.5) was consistent with M3 mediated contractions. p-F-HHSiD inhibited carbachol induced contraction with an affinity consistent with M2 receptors in bladders from NV SCI (pKb=6.4) animals and M3 receptors in bladders from SPV SCI animals (pKb=7.9). Subtype selective immunoprecipitation of muscarinic receptors revealed an increase in total and an increase in M2 receptor density with no change in M3 receptor density in bladders from DEN and NV SCI animals compared to normal or sham operated controls. M3 receptor density was lower in bladders from SPV SCI animals while the M2 receptor density was not different from control. This increase in M2 receptor density is consistent with the change in affinity of the antagonists for inhibition of carbachol induced contractions and may indicate that M2 receptors or a combination of M2 and M3 receptors directly mediate smooth muscle contraction in bladders from DEN and NV SCI rats.  (+info)

Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium. (5/3541)

Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiological methods whether EPO is toxic to mammalian urinary bladder epithelium. Results indicate that EPO, when added to the mucosal solution, increases apical membrane conductance of urinary bladder epithelium only when the apical membrane potential is cell interior negative. The EPO-induced conductance was concentration dependent, with a maximum conductance of 411 microseconds/cm2 and a Michaelis-Menten constant of 113 nM. The EPO-induced conductance was nonselective for K+ and Cl-. The conductance was partially reversed using voltage but not by removal of EPO from the bulk solution. Mucosal Ca2+ reversed the EPO-induced conductance by a mechanism involving reversible block of the conductance. Prolonged exposure (up to 1 h) to EPO was toxic to the urinary bladder epithelium, as indicated by an irreversible increase in transepithelial conductance. These results suggest that EPO is indeed toxic to urinary bladder epithelium via a mechanism that involves an increase in membrane permeability.  (+info)

Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. (6/3541)

IL-8 is a major human neutrophil chemoattractant at mucosal infection sites. This study examined the C-X-C chemokine response to mucosal infection, and, specifically, the role of macrophage inflammatory protein (MIP)-2, one of the mouse IL-8 equivalents, for neutrophil-epithelial interactions. Following intravesical Escherichia coli infection, several C-X-C chemokines were secreted into the urine, but only MIP-2 concentrations correlated to neutrophil numbers. Tissue quantitation demonstrated that kidney MIP-2 production was triggered by infection, and immunohistochemistry identified the kidney epithelium as a main source of MIP-2. Treatment with anti-MIP-2 Ab reduced the urine neutrophil numbers, but the mice had normal tissue neutrophil levels. By immunohistochemistry, the neutrophils were found in aggregates under the pelvic epithelium, but in control mice the neutrophils crossed the urothelium into the urine. The results demonstrate that different chemokines direct neutrophil migration from the bloodstream to the lamina propria and across the epithelium and that MIP-2 serves the latter function. These findings suggest that neutrophils cross epithelial cell barriers in a highly regulated manner in response to chemokines elaborated at this site. This is yet another mechanism that defines the mucosal compartment and differentiates the local from the systemic host response.  (+info)

Nosema notabilis (Microsporidia), its ultrastructure and effect on the myxosporean host Ortholinea polymorpha. (7/3541)

Nosema notabilis Kudo, 1939 produces chain-forming meronts with a dense cell coat in direct contact with the host cell cytoplasm. Cytoplasmic microtubules and membranaceous whorls could be observed in meront cytoplasm. Sporonts differ in that they have a thicker cell wall and more conspicuous endoplasmic reticulum (ER) cisternae. Sporoblasts have an externally ridged cell wall. Spores have an apically located anchoring disc, an isofilar polar tube with 6 to 9 turns and polyribosomal strands in the sporoplasm. Diplokarya occur in all stages. Heavily infected plasmodia of Ortholinea polymorpha (Davis, 1917) reveal marked pathological signs. The most prominent are reduction of surface projections and/or pinocytosis, inflated mitochondria with altered inner structures, affected vegetative nuclei, damage to generative cells and occurrence of various anomalous formations in the plasmodium cytoplasm. The damage may result in complete disintegration of the plasmodium. However, the development of the microsporidian is affected by a remarkably high percentage of teratological stages revealing membranaceous and tubular structures.  (+info)

Neurogenic plasma leakage in mouse airways. (8/3541)

1. This study sought to determine whether neurogenic inflammation occurs in the airways by examining the effects of capsaicin or substance P on microvascular plasma leakage in the trachea and lungs of male pathogen-free C57BL/6 mice. 2. Single bolus intravenous injections of capsaicin (0.5 and 1 micromol kg(-1), i.v.) or substance P (1, 10 and 37 nmol kg(-10, i.v.) failed to induce significant leakage in the trachea, assessed as extravasation of Evans blue dye, but did induce leakage in the urinary bladder and skin. 3. Pretreatment with captopril (2.5 mg kg(-1), i.v.), a selective inhibitor of angiotensin converting enzyme (ACE), either alone or in combination with phosphoramidon (2.5 mg kg(-1), i.v.), a selective inhibitor of neutral endopeptidase (NEP), increased baseline leakage of Evans blue in the absence of any exogenous inflammatory mediator. The increase was reversed by the bradykinin B2 receptor antagonist Hoe 140 (0.1 mg kg(-1), i.v.). 4. After pretreatment with phosphoramidon and captopril, capsaicin increased the Evans blue leakage above the baseline in the trachea, but not in the lung. This increase was reversed by the tachykinin (NK1) receptor antagonist SR 140333 (0.7 mg kg(-1), i.v.), but not by the NK2 receptor antagonist SR 48968 (1 mg kg(-1), i.v.). 5. Experiments using Monastral blue pigment as a tracer localized the leakage to postcapillary venules in the trachea and intrapulmonary bronchi, although the labelled vessels were less numerous in mice than in comparably treated rats. Blood vessels of the pulmonary circulation were not labelled. 6. We conclude that neurogenic inflammation can occur in airways of pathogen-free mice, but only after the inhibition of enzymes that normally degrade inflammatory peptides. Neurogenic inflammation does not involve the pulmonary microvasculature.  (+info)

QINGXIN, Liu et al. Apigenin inhibits cell migration through MAPK pathways in human bladder smooth muscle cells. Biocell [online]. 2011, vol.35, n.3, pp.71-79. ISSN 0327-9545.. Apigenin, a nonmutagenic flavonoid, has been shown to possess free radical scavenging activities, anticarcinogenic properties, antioxidant and anti-inflammatory effects. Recently, apigenin was reported to cause gastric relaxation in murine. To assess possible effects of apigenin on migration of bladder smooth muscle (SM) cell, we isolated SM cells from peri-cancer tissue of human bladder and established a cell model that was capable to overexpress transiently MEKK1 (MEK kinase 1). Results showed that overexpression of active human MEKK1 by adenoviruses infection induced migration of human bladder smooth muscle (hBSM) cells and phosphorylation of MAPKs, ERK, JNK and p38, which are the downstream molecules of MEKK1. Then, hBSM cell overexpressing MEKK1 were exposed to apigenin (50 μM). Our data indicated that apigenin ...
The effects of hypotonic solutions on intracellular Ca2+ were determined on primary cultures of human detrusor smooth muscle cells. In the presence of external Ca2+, changing from a solution containing 290 mosmol l-1 to one containing 240 mosmol l-1 (80% normal tonicity) activated a rise in intracellular Ca2+. If the exposure to 240 mosmol l-1 was followed by exposure to 150 mosmol l-1 (50% normal tonicity) a further increase in Ca2+ was noted. Exposure to hypotonic solutions which contained nominally zero Ca2+ also resulted in a rise in intracellular Ca2+, suggesting that mechanical perturbation of the surface membrane can mobilize Ca2+ directly from intracellular stores. Stimulation of cells with a brief exposure to agonist (histamine, 5 microM) in the nominal absence of external Ca2+ produced a release of Ca2+ from intracellular stores. Under these conditions the response to a subsequent hypotonic stimulation was small or absent. These observations suggest that hypotonic stress induces a mobilization
The uroepithelium lines the urinary bladder, urethra and the lower renal pelvis. It provides a tight blood-urine barrier that prevents the unregulated movement of solutes, ions and metabolites present in the urine. Apart from forming a robust barrier, a growing body of evidence supports the role of the uroepithelium as a sensory transducer that is sensitive to extracellular biochemical and mechanical stimuli. One of the mediators that is released from the uroepithelium and impacts bladder activity is adenosine. Adenosine is a well-known stress relieving hormone in other organ systems and the bladder lumen is a region of constant stress due to cyclical filling and voiding of urine, therefore I hypothesized that adenosine has an impact on urinary bladder function under stress. First I assessed the mechanism of adenosine turnover and how luminal adenosine affects bladder function. I report that adenosine is released from the mucosal and serosal surfaces of the uroepithelium when the tissue is ...
The aim of this study was to characterize endothelin receptor subtypes of the detrusor muscle of the human urinary bladder. The receptor subtypes mediating endothelin (ET)-1-induced activity in the human detrusor smooth muscles have been characterized using isometric contraction and reverse transcription-polymerase chain reaction (RT-PCR). ET-1 (a non-selective ET receptor agonist; 10-10 M to 10-6 M) exhibited concentration-dependent contractions in human urinary bladder with a plateau at concentrations above 3×10-7 M. Neither IRL1620 nor sarafotoxin S6c (both ETB-selective agonists; 10-10 M to 10-6 M) elicited contractile activity in the human urinary bladder detrusor smooth muscle. FR139317 (an ETA-selective antagonist; 10-7 M to 10-5 M) produced a marked shift to the right of the ET-1 concentration-response curve in human urinary bladder detrusor smooth muscle (from the Schild plot TpA2 = 7.96; slope = 0.95). In contrast, RES701-1 (an ETB-selective antagonist; 10-7 M to 10-5 M) had no effect ...
TY - JOUR. T1 - Normal reference values for bladder wall thickness on CT in a healthy population. AU - Fananapazir, Ghaneh. AU - Kitich, Aleksandar. AU - Lamba, Ramit. AU - Stewart, Susan L. AU - Corwin, Michael T. PY - 2018/2/1. Y1 - 2018/2/1. N2 - Purpose: To determine normal bladder wall thickness on CT in patients without bladder disease. Materials and methods: Four hundred and nineteen patients presenting for trauma with normal CTs of the abdomen and pelvis were included in our retrospective study. Bladder wall thickness was assessed, and bladder volume was measured using both the ellipsoid formula and an automated technique. Patient age, gender, and body mass index were recorded. Linear regression models were created to account for bladder volume, age, gender, and body mass index, and the multiple correlation coefficient with bladder wall thickness was computed. Bladder volume and bladder wall thickness were log-transformed to achieve approximate normality and homogeneity of variance. ...
Increased phasic activity in the bladder smooth muscle of animal models and patients with detrusor overactivity has been suggested to underlie the pathophysiology of overactive bladder. Potassium (K+) channels are key regulators of bladder smooth muscle tone and thus may play a role in this altered phasic activity. In this study the effects of K+ channel modulators on the phasic activity of bladder strips from the streptozotocin-induced diabetic rat model of bladder dysfunction were investigated. Bladder strips from rats 1 week following streptozotocin administration and age-matched controls were mounted in tissue baths at 37 °C and the effects of K+ channel modulators on resting basal tension or phasic activity induced by a low concentration of carbachol (0.5 μM) were investigated. Activation of BKCa channels by NS1619 had a minor inhibitory effect on carbachol-induced phasic activity of bladder strips from control and diabetic rats, and significantly inhibited amplitude only at 30 μM. Activation of
TY - JOUR. T1 - Spontaneous contractions of the pig urinary bladder. T2 - The effect of ATP-sensitive potassium channels and the role of the mucosa. AU - Akino, Hironobu. AU - Chapple, Christopher R.. AU - McKay, Neil G.. AU - Cross, Rebecca L.. AU - Murakami, Shigetaka. AU - Yokoyama, Osamu. AU - Chess-Williams, Russell. AU - Sellers, Donna J.. PY - 2008/11. Y1 - 2008/11. N2 - OBJECTIVE: To investigate the influence of the mucosa on the inhibitory effects of the ATP-sensitive potassium channel (KATP channel) opener, cromakalim, on the spontaneous contractions of pig bladder strips from the bladder dome and trigone. Little is known about the influence of the mucosa on spontaneous contractions and whether the nature of these contractions differs between the bladder dome and trigone. MATERIALS AND METHODS: Paired longitudinal strips of female pig bladders were isolated from the dome and trigone. The mucosa was removed from one strip per pair and tissues were set up in organ baths. Spontaneous ...
C57BL/6-GFP Mouse Bladder Epithelial Cells from Creative Bioarray are isolated from C57BL/6-GFP-Tg(CAG-EGFP)1Osb/J mouse bladder tissue of pathogen-free laboratory mice. C57BL/6-GFP Mouse Bladder Epithelial Cells are grown in a T25 tissue culture flask pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarrays Culture Complete Growth Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x10^6cells per ml and is delivered frozen. Cells can be expanded for 3-7 passages at a split ratio of 1:2 under the cell culture conditions specified by Creative Bioarray. Repeated freezing and thawing of cells is not recommended ...
The urinary bladder is the organ that collects urine excreted by the kidneys before disposal by urination. The urinary bladder is a triangular, hollow and distensible (or elastic) organ that is located in the lower abdominal region. Urine enters the bladder via the ureters and exits via the urethra. Bladders occur throughout much of the animal kingdom, but they are very diverse in form and in some cases are not homologous with the urinary bladder in humans. The human urinary bladder is derived in embryo from the urogenital sinus and, it is initially continuous with the allantois. In males, the base of the bladder lies between the rectum and the pubic symphysis. It is superior to the prostate, and separated from the rectum by the rectovesical excavation. In females, the bladder sits inferior to the uterus and anterior to the vagina; thus, its maximum capacity is lower than in males. It is separated from the uterus by the vesicouterine excavation. In infants and young children, the urinary bladder ...
The urinary bladder is the organ that collects urine excreted by the kidneys before disposal by urination. The urinary bladder is a triangular, hollow and distensible (or elastic) organ that is located in the lower abdominal region. Urine enters the bladder via the ureters and exits via the urethra. Bladders occur throughout much of the animal kingdom, but they are very diverse in form and in some cases are not homologous with the urinary bladder in humans. The human urinary bladder is derived in embryo from the urogenital sinus and, it is initially continuous with the allantois. In males, the base of the bladder lies between the rectum and the pubic symphysis. It is superior to the prostate, and separated from the rectum by the rectovesical excavation. In females, the bladder sits inferior to the uterus and anterior to the vagina; thus, its maximum capacity is lower than in males. It is separated from the uterus by the vesicouterine excavation. In infants and young children, the urinary bladder ...
If these nerves are damaged by illness or injury, the muscles may not be able to tighten or relax at the right time. Neurogenic bowel is the loss of normal bowel function. This interferes with the normal ability to store and eliminate waste. The nerves of the cauda equina provide motor and sensory function to the legs and the bladder. This means that people are expected to have the strength to withhold voiding until a socially acceptable time. A device can be placed under your skin to deliver mild electrical pulses to the nerves that control bladder function. Some of these sacral nerves go to the rectum, the bladders detrusor muscle, levator ani muscle, and external sphincter muscles, controlling their activities. In turn, In turn, Bladder function - neurological control - Health Video: MedlinePlus Medical Encyclopedia s y . Areflexic bowel usually results from SCI that damages the lower end of the spinal cord or the nerve branches that go out to the bowel. The bladder is a hollow organ located ...
TY - JOUR. T1 - Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder. AU - Ajalloueian, Fatemeh. AU - Lemon, Greg. AU - Hilborn, Jöns. AU - Chronakis, Ioannis S.. AU - Fossum, Magdalena. PY - 2018. Y1 - 2018. N2 - The urinary bladder is a complex organ with the primary functions of storing urine under low and stable pressure and micturition. Many clinical conditions can cause poor bladder compliance, reduced capacity, and incontinence, requiring bladder augmentation or use of regenerative techniques and scaffolds. To replicate an organ that is under frequent mechanical loading and unloading, special attention towards fulfilling its biomechanical requirements is necessary. Several biological and synthetic scaffolds are available, with various characteristics that qualify them for use in bladder regeneration in vitro and in vivo, including in the treatment of clinical conditions. The biomechanical properties of the native bladder can be investigated using ...
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PURPOSE: To investigate whether delivering an increased radiation dose to the tumor-bearing region of the bladder alone would improve local disease control without increasing treatment toxicity. METHODS AND MATERIALS: A total of 149 patients with unifocal T2-T3N0M0 bladder carcinoma were randomized between whole bladder conformal radiotherapy (WBRT, 52.5 Gy in 20 fractions, n = 60) and partial bladder conformal RT (PBRT) to tumor alone with 1.5-cm margins within either 4 weeks (PBRT4, 57.5 Gy in 20 fractions, n = 44) or 3 weeks (PBRT3, 55 Gy in 16 fractions, n = 45). The response was assessed cystoscopically after 4 months. RESULTS: The 5-year overall and CFS rate was 58% and 47%, respectively, for the whole population. The CR rate was 75% for WBRT, 80% for PBRT4, and 71% for PBRT3 (p = 0.6), with a 5-year local control rate of 58%, 59%, and 34%, respectively (p = 0.18). Solitary new tumors arose within the bladder, outside the irradiated volume, in 6 (7%) of 89 patients who underwent PBRT. The ...
Synonyms for atonic urinary bladder in Free Thesaurus. Antonyms for atonic urinary bladder. 13 words related to urinary bladder: apparatus urogenitalis, genitourinary apparatus, genitourinary system, systema urogenitale, urinary apparatus.... What are synonyms for atonic urinary bladder?
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Study Objective: To determine the validity of bladder scan BV13000 in detection of bladder volume in immediate postpartum women. Methodology: A prospective cross sectional study conducted in Hospital Tengku Ampuan Afzan, Pahang from 1st September to 30 November 2010, A total of 193 women who had undergone Caesarean section were recruited on postpartum day 1. Prior to removal of Foleys catheter, their bladder volumes were first estimated by bladder scan BV13000. Immediately the bladder was then catheterized for the true bladder volume followed by 2D ultrasound bladder scanning to ensure that it was completely emptied. The data was analyzed using SPSS software version 18(SPSS Inc. Chigaco, Illinois). P value of less than 0.05 is considered as statistically significant. Resul : There were a total of 193 women recruited with the mean age of 28.84 years (SD 5.516) with mean BMI of 29.69( SD 5.69) kg/m2 and fundal height of 16cm (SD 2.382 ). The mean for time interval between bladder scan and ...
Intravesical electrical stimulation (IVES) has been used in treatment of patients with urinary bladder dysfunctions for more than four decades. While some investigators have reported excellent results others have observed less convincing effects or outright failures. The discrepancies may reflect differences in patient selection or stimulation procedure. A better theoretical understanding of the IVES working mechanism might help to improve the success rate of the treatment. The aims of the present study were to provide such information.. Experiments were performed on adult female cats and rats under /alpha/-chloralose anesthesia. IVES was delivered by a catheter electrode in the bladder. At proper intensity and frequency, IVES evoked reflex detrusor contractions that were abolished by bilateral rhizotomy of sacral dorsal roots. Stimulation parameters and response characteristics revealed that bladder mechanoreceptor A/delta/ afferents were activated by the IVES, the same afferents that drive the ...
Zhou, Y.,Tan, C.K.,Ling, E.A. (1997). Distribution of NADPH-diaphorase and nitric oxide synthase-containing neurons in the intramural ganglia of guinea pig urinary bladder. Journal of Anatomy 190 (1) : 135-145. [email protected] Repository. https://doi.org/10.1017/S0021878296001549 ...
Spinal cord injury (SCI) disconnects supraspinal micturition centers from the lower urinary tract resulting in immediate and long-term changes in bladder structure and function. While cervical and high thoracic SCI have a greater range of systemic effects, clinical data suggest that those with lower (suprasacral) injuries develop poorer bladder outcomes. Here we assess the impact of SCI level on acute changes in bladder activity. We used two SCI models, T3 and L2 complete transections in male Wistar rats, and compared bladder pressure fluctuations to those of naïve and bladder-denervated animals. By 2 days after L2 transection, but not T3 transection or bladder denervation, small amplitude rhythmic contractions (1 mmHg, 0.06 Hz) were present at low intravesical pressures (
Looking for irritable urinary bladder? Find out information about irritable urinary bladder. a distensible membranous sac in which the urine excreted from the kidneys is stored the organ in which urine accumulates before being excreted from the body... Explanation of irritable urinary bladder
TY - JOUR. T1 - The effect of adriamycin (ADR) on a human bladder cell line (MGH-U1) grown as a monolayer, as spheroids and in immune-deprived mice. AU - Erlichman, C.. AU - Vidgen, D.. AU - Tannock, I. F.. PY - 1982/1/1. Y1 - 1982/1/1. UR - http://www.scopus.com/inward/record.url?scp=0020063457&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0020063457&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0020063457. VL - Vol. 23. JO - Proceedings of the American Association for Cancer Research. JF - Proceedings of the American Association for Cancer Research. ER - ...
The amount of urine left in the urinary bladder after voiding, depends on the age and gender of the patient, Some medications and medical problems such as diabetes or multiple sclerosis may affect how well the bladder empties. To some extent, the amount of urine present in the bladder prior to urination also affects how much is left at the end of urination.. Normal bladder capacity is around 500 ml but varies. If someone has 150 ml left in the bladder, that means that 30% of the bladder is filled already right after they have urinated. As a result, the time they have to fill the bladder (the time until they get the urge to pee again) is shorter by 30%. If bladder capacity is also small, for example only 300 ml, and post-void residual is 150 ml, then the bladder empties only half-way, and this may be one of the reasons people with incomplete bladder emptying have a frequent urge to urinate.. Younger patients should not have any urine left in the bladder after urination or a minimal amount. In ...
Dive into the research topics of Prediction of radiosensitivity in human bladder cell lines using nuclear chromatin phenotype.. Together they form a unique fingerprint. ...
Sphincter muscle of urinary bladder definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
Purpose Detrusor overactivity contributes to bothersome constellation of lower urinary tract symptoms (LUTS) in men and women as they age. However, the underlying mechanisms of non-obstructive detrusor overactivity and LUTS remain largely unknown. Growing evidence suggests that ischemia may be an independent factor in the development of non-obstructive bladder dysfunction. Our goal was to determine the effects of ischemia on detrusor function and voiding behavior and define redox-mediated cellular stress and cell survival signaling in the ischemic bladder. Materials and methods Male Sprague Dawley rats were randomly divided into treatment (n=8) and control (n=8) groups. In the treatment group, iliac artery atherosclerosis and chronic bladder ischemia were induced. At 8 weeks after bladder ischemia, voiding patterns were examined in metabolic cages, cystometrograms were recorded in conscious animals, and then bladder blood flow was measured under general anesthesia. Bladder tissues were processed ...
Male urinary bladder inspection - Circumcision - Wikipedia, the free encyclopedia. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
AIMS: The functional integration of the smooth muscle of enterocystoplasties into the detrusor muscle was investigated in an awake-rat cystometry model and in vitro.. METHODS: The upper fourth of the bladder was removed, and a detubularized appendiceal segment (7 x 7 mm), with preserved vasculature, was incorporated into the bladder. After 1 or 3 months, a catheter was fixed to the top of the bladders. After a 3-day recovery, cystometries were performed. In separate experiments, agonist and nerve-induced responses were evaluated on isolated bladder strips.. RESULTS: Cystometries revealed reduced basal pressure and micturition pressure in enterocystoplasty (ECP) bladders. Bladder capacity and micturition volume were increased. Threshold pressure (pressure immediately before micturition) was significantly lower at 1 month, but not at 3 months. Bladder compliance was significantly higher in the operated at 1 month but not at 3 months. Threshold tension did not differ between control and ...
BALB/c Mouse Bladder Microvascular Endothelial Cells from Creative Bioarray are isolated from bladder tissue of pathogen-free laboratory mice. BALB/c Mouse Bladder Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarray Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and are delivered frozen. The method we use to isolate endothelial cells was developed based on a combination of established and our proprietary methods. These cells are pre-coated with PECAM-1 antibody, following the application of magnetic pre-coated with secondary antibody ...
Question - Diabetes, stroke, full bladder. Treatment for bladder fullness, advise?. Ask a Doctor about diagnosis, treatment and medication for Stroke, Ask a Urologist
Squamous cell carcinoma of the urinary bladder occurs after metaplasia of the urinary bladder epithelium from transitional cell to squamous cell. It can occurs in settings of schistosomaisis, chronic irritation by stones, and chronic infection.
Bladder overdistension has been found to cause transitional morphological changes in innervation which correlate with changes in micturition and bladder contractility. We investigated the influence of overdistension on bladder wall morphology using histological and enzyme histochemical methods. Overdistension was induced in female rats for 3 h by forced diuresis and balloon obstruction of the bladder neck. Oedema was seen beneath the mucosa at 12 h, with hyperemia and haemorrhages. The urothelium was mostly intact, although enzymes leaked out of the epithelial cells. The changes were increased at 24 h. The urothelium also showed some disruptions and degenerative vacuolization. The oedema reached its maximum at 48 h, and large numbers of inflammatory cells were also seen. The urothelium was disruptured in many places and vacuolated, but the subendothelial capillaries remained normal. Damage to some muscle cells was seen. After 7 days the oedema had disappeared and the urothelium was continuous. Enlarged
The complex model of the lower part of the urinary consists of the detrusor smooth muscle cell model and the detailed 1D model of the urethra flow. In future this model will allow to simulate the influence of different drugs and mechanical obstructions in the bladder neck and urethra. A general muscle model involving the calcium dynamics in the smooth muscle cell and the growth and remodelling theory will be shortly introduced. The main part is devoted to the development of a simple bladder model and the detrusor contraction during voiding together with the detailed model of the urethra flow ...
According to prevailing assumptions, UPEC strains are strictly extracellular pathogens. In this study, however, we provide evidence that host cell invasion enhances the ability of UPEC to successfully infect the bladder epithelium. Upon making contact with superficial epithelial cells in the bladder lumen, type 1-piliated UPEC induces a cascade of signaling events leading to bacterial internalization (27, 29). Following internalization UPEC is able to replicate, resulting in the formation of large collections of intracellular bacteria, which due to their appearance we have termed bacterial factories. UPEC strains were also shown to have the capacity to flux out of bladder epithelial cells, a process that may allow bacteria to escape from host superficial cells that are induced to exfoliate in response to infection. Bacteria exiting dying host cells are often filamentous, enabling them to maintain contact with the bladder epithelium as they leave one host cell and interact with neighboring and ...
Eviprostat is a popular phytotherapeutic agent for the treatment of lower urinary tract symptoms (LUTS). At present, the signaling mechanisms underlying its therapeutic effects are still poorly understood. Given that cAMP has been reported to suppress cell hyperplasia and hypertrophy in various pathological situations, we asked whether the effect of Eviprostat could be ascribed to the activation of the cAMP signaling pathway. In the study, exposure of cAMP response element (CRE)-secreted alkaline phosphatase (SEAP) (CRE-SEAP)-reporter cells to Eviprostat elevated SEAP secretion, which was associated with an increased phosphorylation of vasodilator-stimulated phosphoprotein (VASP) and cAMP-response element-binding protein (CREB), as well as enhanced expression of CRE-regulated protein connexin43, indicating an activation of the cAMP signaling pathway. Consistent with these observations, Eviprostat-induced expression of Cx43 was abolished in the presence of adenylyl cyclase inhibitor SQ22536 or PKA
Do you suffer from inflammation of the urinary bladder? Magnetic therapy can help you. Find out why physicians recommend magnetic therapy for inflammation of the urinary bladder.
Urinary bladder matrix, a skin substitute material made from porcine bladder, can be used successfully in periorbital reconstructive procedures, Ophthalmology Times reports.
functional abnormality (such as a very abnormal heart beat or mental. although there is still scientific and economic controversy about our conclusion, we would argue that, at a minimum, there is an ethical obligation to present the option of an 18-22-week routine obstetric ultrasound examination in clinical centers in which quality ultrasound is available. try to date the pregnancy, exclude twins and detect any fetal. important large scale studies emerged to address the issue: the radius study (routine antenatal diagnostic imaging with ultrasound) with a cohort of 15,000 low-risk pregnancies in the united states in 1993 and the eurofetus study in europe in 1997 in which 200,000 low-risk pregnant women in 60 hospitals had obstetric ultrasound examinations performed in centers proficient in prenatal diagnosis. there were definitely no boy parts down there, and she started. sonogram and told that nothing is wrong other than the. the sonographer will put some gel on your tummy and move a small ...
Cystometry is a diagnostic procedure used to identify problems with the filling and emptying of the urinary bladder. This test measures the amount of volume or urine in the bladder compared with the bladder pressure and the persons perception of bladder fullness. Cystometry provides information about the muscle function, mechanics, and nerve response of the bladder and urinary tract.. A normally functioning bladder sends messages to the brain via nerve pathways when it needs emptying. The spinal cord then transmits a message to the bladder to contract and begin the reflex of urinating. A person can override this reflex voluntarily by holding his or her urine.. Some medical conditions may interfere with the muscular function or nerve pathways between the bladder and the brain. These conditions may lead to urinary incontinence (loss of bladder control) or urinary obstruction. Cystometry may be indicated to determine the source of such problems. It is often done together with Uroflowmetry, which ...
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Nowadays, a role of the whole range of factors of hyperactive bladder development is being discussed.. They are as follows:. - Sex and Age Hyperactive bladder risk increases with the age. The critical age is above 60 - elderly people have maximal probability to get affected by hyperactive bladder. For men, this risk is explained by prostatic hyperplasia the symptoms of which are present in almost all men above 60. Nevertheless, absence of hyperplasia doesnt exclude occurrence of age-related changes of bladder which are nearly identical in both, men and women.. Hyperactive bladder development in elderly people is usually an accompanying disease with neurogenic and vascular component, such as diabetes, cerebrovascular pathology, atherosclerosis of huge vessels, etc.. - Genetic Factor. It is difficult to detect this factor in hyperactive bladder syndrome. For unbiased estimate of heredity role, it is essential to examine affined individuals under conditions of similar environment and lifestyle. ...
Bladder regeneration based on minced bladder mucosa in vivo expansion is an alternative to in vitro culturing of urothelial cells. Here, we present the design of a hybrid, electrospun poly(lactic-co-glycolide) (PLGA) - plastically compressed (PC) collagen scaffold that could allow in vivo bladder mucosa expansion. Optimisation of electrospinning was performed in order to obtain increased pore sizes and porosity to consolidate the construct and to support neovascularisation and tissue ingrowth. Tensile tests showed an increase in average tensile strength from 0.6 MPa for PC collagen to 3.57 MPa for the hybrid construct. The optimised PLGA support scaffold was placed between two collagen gels, and the minced tissue was distributed either on top or both on top and inside the construct prior to PC; this was then cultured for up to four weeks. Morphology, histology and SEM demonstrated that the construct maintained its integrity throughout cell culture. Cells from minced tissue migrated, expanded and ...
Intravesical Adriamycin treatment was given to 22 patients with carcinoma in situ of the urinary bladder. The treatment schedule consisted of monthly Adriamycin instillations in a dose related to bladder capacity. Endoscopic inspection with multiple bladder biopsies and cytoanalysis of urine was performed after every third instillation. In two patients there was lasting disappearance of the carcinoma in situ. Another 10 patients possibly had a beneficial effect of the treatment. The remaining 10 patients showed persistent malignancy and in 6 of these, progression of carcinoma in situ during Adriamycin treatment necessitated cystectomy or radiotherapy. The histologic and cytologic findings showed distinct variability in most patients, with atypia or even absence of malignant cells often followed by recurrence. Adriamycin was discontinued in four cases because of severe cystitis, and in one case because of an anaphylactoid reaction following instillation of the drug.
Looking for bladder cell? Find out information about bladder cell. Any of the large vacuolated cells in the outer layers of the tunic in some tunicates Explanation of bladder cell
Regions of tissue having reduced electrical propagation are created in a bladder to affect its electrical or mechanical properties. To create these tissue regions, a tubular device is advanced through the urethra leading to the interior of the bladder, a distal expandable structure of the device is expanded to contact the inner wall of the bladder, and electrodes or other active energy delivery elements of the device are activated to deliver ablation energy. The electrodes or other active energy delivery elements are disposed over the expandable structure which is shaped to conform to the interior of the bladder. The inner wall of the organ is ablated in a predetermined pattern. The same or other electrodes disposed over the expandable structure can used to electrically map the bladder. This map of electrical activity can be used to create the predetermined pattern.
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TY - JOUR. T1 - Transforming growth factor-β1 mediates migration in cultured human control and exstrophy bladder smooth muscle cells. AU - Suson, Kristina D.. AU - Stec, Andrew A.. AU - Gearhart, John Phillip. AU - Shimoda, Larissa. PY - 2012/10. Y1 - 2012/10. N2 - Purpose: Transforming growth factor-β1 regulates extracellular matrix composition, and impacts function and proliferation in multiple cell types, including bladder smooth muscle cells. In this study we evaluated the response to transforming growth factor-β1 in cultured exstrophy and control bladder smooth muscle cells. Materials and Methods: Primary bladder smooth muscle cell cultures were established from patients with bladder exstrophy or vesicoureteral reflux. Smooth muscle specific α-actin and heavy chain myosin expression was determined using immunohistochemistry. Cell migration, intracellular calcium concentration and proliferation were determined after incubation for 24 to 48 hours in basal media, with or without ...
Tobacco smoking is a major risk factor for human cancers including urinary bladder carcinoma. In a previous study, nicotine enhanced rat urinary bladder carcinogenesis in a two-stage carcinogenesis model. Nicotine also induced cytotoxicity in the bladder urothelium in a short-term study. In the present study, male rats were treated with nicotine (40 ppm) in drinking water co-administered with the NADPH oxidase inhibitor, apocynin (0, 250 or 750 mg/kg) in diet for 4 weeks. The apocynin treatment induced no clinical toxic effects. Reduction of reactive oxygen species (ROS) by apocynin was confirmed by immunohistochemistry of 8-OHdG in the bladder urothelium. Incidences of simple hyperplasia, cell proliferation and apoptosis were reduced by apocynin treatment in the bladder urothelium. However, despite reduction of cell proliferation (labeling index), apocynin did not affect the incidence of simple hyperplasia, apoptosis, or ROS generation in the kidney pelvis urothelium, in addition to 8-OHdG ...
The urinary bladder sits in a unique position inferior to the peritoneum, a membrane that lines most of the abdominopelvic cavity. Due to its position, the outermost layer of the superior urinary bladder is made of serous membrane continuous with the peritoneum. Serous membrane provides protection to the bladder from friction between organs in the abdominopelvic cavity. The surface of the lateral and inferior sides of the urinary bladder forms a layer of loose connective tissue known as the adventitia. The adventitia loosely connects the urinary bladder to the surrounding tissues of the pelvis.. The urinary bladder functions as a storage vessel for urine to delay the frequency of urination. It is one of the most elastic organs of the body and is able to increase its volume greatly to accommodate between 600 to 800 ml of urine at maximum capacity. Transitional epithelium, elastic fibers, and visceral muscle tissue in the walls of the urinary bladder contribute to its distensibility and ...
TY - JOUR. T1 - Superimposed histologic and genetic mapping of chromosome 17 alterations in human urinary bladder neoplasia. AU - Chaturvedi, Vijaya. AU - Li, Li. AU - Hodges, Sherie. AU - Johnston, Dennis. AU - Ro, Jae Y.. AU - Logothetis, Christopher. AU - Von Eschenbach, Andrew C.. AU - Batsakis, John G.. AU - Czerniak, Bogdan. PY - 1997. Y1 - 1997. N2 - Multistep alterations of chromosome 17 in the progression of human urinary bladder neoplasia were studied by superimposed histologic and genetic mapping. The p53 gene was included in the analysis as a model tumor suppressor gene that is frequently involved in urothelial carcinogenesis. The strategy provided a systematic approach to the study of multistep genomic alterations that occur as neoplasia progresses from precursor intraurothelial conditions to invasive cancer. This was accomplished by sampling the entire mucosa of the organ and displaying microscopically identified invasive cancer and precursor conditions in the form of a histologic ...
Purpose Type 3 muscarinic receptors, which are present in the bladder wall, are important for bladder function. However, their role in the context of the urothelium is not well defined. Understanding the role of type 3 muscarinic receptors has been limited by the lack of specific type 3 muscarinic receptor antibodies. Thus, we identified a specific type 3 muscarinic receptor antibody and investigated the site of type 3 muscarinic receptors in sham operated and obstructed guinea pig bladders. Materials and Methods The specificity of 4 commercially available type 3 muscarinic receptor antibodies was determined. Immunohistochemistry was then done in bladder tissue from sham operated and obstructed guinea pig bladders. Results One of the 4 antibodies examined had the needed specificity in terms of blocking peptide and Western blot characterization. Using this antibody type 3 muscarinic receptor immunoreactivity was associated with muscle cells, nerves and interstitial cells. Four types of ...
The urinary symptoms created by a neurogenic bladder depend on the cause or abnormality that has caused the problem. They often include urinary incontinence as well as frequent urination, an urgent sensation of urination, waking up at night to urinate (nocturia), inability to empty the bladder fully or an inability to urinate at all (urinary retention).Common symptoms described as overactive bladder can also be due to a neurogenic bladder. Symptoms can include urinating frequently in small amounts, sensation of not being able to empty all urine from the bladder, and loss of bladder control. Overactive bladder may also be present in the absence of a defined neurological disease or disorder (idiopathic overactive bladder.) Other symptoms can also be attributed to an underactive bladder, where the bladder cannot squeeze hard enough to empty completely, resulting in sensation of a full bladder that may be associated with urine leakage, inability to tell when the bladder is full, difficulty starting to
Looking for online definition of cancer of urinary bladder in the Medical Dictionary? cancer of urinary bladder explanation free. What is cancer of urinary bladder? Meaning of cancer of urinary bladder medical term. What does cancer of urinary bladder mean?
TY - JOUR. T1 - Effects of isolectin B4-conjugated saporin, a targeting cytotoxin, on bladder overactivity induced by bladder irritation. AU - Nishiguchi, Jun. AU - Sasaki, Katsumi. AU - Seki, Satoshi. AU - Chancellor, Michael B.. AU - Erickson, Kristin A.. AU - De Groat, William C.. AU - Kumon, Hiromi. AU - Yoshimura, Naoki. PY - 2004/7. Y1 - 2004/7. N2 - In order to clarify the functional role of the isolectin B4 (IB4)-binding afferent pathway in the micturition reflex, we investigated the effects on bladder activity of intrathecal application of the IB4-saporin conjugate, a targeting cytotoxin that destroys neurons binding IB4. In rats, IB4-saporin (2.5 μm) or vehicle was administered through an intrathecal catheter implanted at the level of the L6-S1 spinal cord. Three weeks after IB4-saporin administration, cystometry in conscious animals revealed a reduction in bladder overactive responses induced by intravesical capsaicin or ATP infusion without affecting normal voiding function. In ...
Arachidonic metabolites, more specifically PGs, are released from the bladder into the general circulation in response to distension (79-81). It was found that PGs in the bladder wall originate from both the urothelial and muscle layers (79, 80). The exact role of this endogenous PG is not known, but it is well documented that exogenous PG alters bladder motor activity in vitro and in vivo and that it can also influence the micturition reflex in humans, (82-84) rats, (85) guinea pigs, (86) rabbits (87) and monkeys (88). The main PGs synthesized in the bladder are PGE2 (79-81) and PGI2 (89). PGs are locally synthesized in the bladder muscle and mucosa. This synthesis is initiated by stretch of the detrusor muscle, bladder nerve stimulation, bladder mucosa damage and inflammation mediators. The effects of PGs in the bladder have been studied in numerous studies. These studies have shown that bladder infusion with PGE2 enhances the micturition reflex and that urine levels of PGE2 are increased in ...
Postnatal response of the gall bladder to feeding was studied in 28 preterm infants (gestational age 24-37 weeks) by ultrasonography immediately before feeding and one hour after feeding. Nineteen of the infants were studied once during the first week of life, and nine infants were studied weekly from a postconceptional age of 27-31 until a postprandial gall bladder contraction was seen. A contraction index was calculated as a percentage decrement of the surface area of the gall bladder from its initial value. All preterm infants of more than 33 weeks gestation showed a gall bladder response to feeding with a contraction index of at least 50%. Very preterm infants (gestational age 27-32 weeks) showed no postprandial gall bladder contraction or the contraction index was under 50%. In a follow up study of nine very preterm infants, the contraction index exceeded 50% at a postconceptional age of 29 to 32 weeks. One infant with prolonged feeding problems had no postprandial gall bladder response ...
University of Iowa News. March 25, 2005 UI Study Seeks Adults With Urinary Frequency, Painful Bladder Problems. Men and women age 18 and older with certain urinary frequency and bladder problems are invited to participate in a University of Iowa research study on interstitial cystitis and painful bladder syndrome.. The study will compare the safety and effectiveness of an investigational medication to placebo (inactive substance) in reducing symptoms. Interstitial cystitis is a chronic, painful inflammatory condition of the bladder wall. An estimated 10 million people in the United States are affected by interstitial cystitis and painful bladder syndrome.. People with increased daytime and nighttime urinary frequency who have never sought treatment are eligible to participate. Individuals also eligible to participate are people who have not yet received treatment for lower abdominal or pelvic pain associated with a full bladder but who do not have a urinary tract infection.. Women who are ...
The urinary bladder is a temporary storage reservoir for urine. It is located in the pelvic cavity, posterior to the symphysis pubis, and below the parietal peritoneum. The size and shape of the urinary bladder varies with the amount of urine it contains and with pressure it receives from surrounding organs.. The inner lining of the urinary bladder is a mucous membrane of transitional epithelium that is continuous with that in the ureters. When the bladder is empty, the mucosa has numerous folds called rugae. The rugae and transitional epithelium allow the bladder to expand as it fills.. The second layer in the walls is the submucosa that supports the mucous membrane. It is composed of connective tissue with elastic fibers.. The next layer is the muscularis, which is composed of smooth muscle. The smooth muscle fibers are interwoven in all directions and collectively these are called the detrusor muscle. Contraction of this muscle expels urine from the bladder. On the superior surface, the outer ...
The concentration-effect relationships of carbachol were studied for three different responses of detrusor muscle of rabbit urinary bladder: the mechanical response, the increase of 45Ca uptake and the displacement of [3H]quinuclidinyl benzilate (QNB) from muscarinic receptors. The EC50 for carbachol in production of contractile responses of the detrusor muscle was observed to be 0.27 microM. The 45Ca uptake by detrusor muscle strips was studied by the lanthanum-residual wash out method. Carbachol increased 45Ca uptake with an EC50 of 12.7 microM. [3H]QNB binding was performed on homogenates of rabbit bladder detrusor muscle. By Scatchard analysis, the receptor density was found to be 47.2 fmol/mg of protein and the KD 0.074 nM. The contractile responses, the 45Ca uptake and the specific [3H]QNB binding were all blocked by atropine and so are taken to represent muscarinic receptor-mediated phenomena. Carbachol displacement of [3H]QNB yielded an EC50 of 135 microM and a Kl of 42 microM. It is ...
In the current study all of the patients underwent sigmoid cystoplasties for 1-12 months (mean, 4.6 ± 1.2 months) because of a neurogenic bladder secondary to incomplete spinal cord injuries, meningoceles, or spina bifida. After recovering from surgery, the patients were asked to empty their bladders by CIC; however, the mean bladder capacity was only 280.5 ± 11.7 ml at early follow-up post-operatively based on urodynamic evaluation, which was unsatisfactory for those subjects who had undergone cystoplasty. In our previous research [1], we showed that the most common problem within 6 months post-operatively was incontinence, which might have resulted from the weakened function of the sphincter post-operatively. The presence of an indwelling urethral catheter for a long period could contribute to sphincter weakness because the maximal urethral pressure at rest was significantly decreased during the 6-month follow-up examination compared with the pre-operative pressure. Automatic contraction of ...
Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction are attenuated with the NLRP3 inhibitor glyburide.
Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of the limitations of in vitro experiments on isolated human detrusor included inability to evaluate in vivo effects of TREK-1 on voiding function, as the channel is also expressed in the nervous system, and may modulate micturition via neural pathways. Therefore, in the present study, we aimed to assess the role of TREK-1 channel in bladder function and voiding patterns in vivo by using TREK-1 knockout (KO) mice. Adult C57BL/6 J wild-type (WT, N = 32) and TREK-1 KO (N = 33) mice were used in this study. The overall phenotype and bladder function were evaluated by gene and protein expression of TREK-1 channel, in vitro contractile experiments using detrusor strips in response to stretch and pharmacological stimuli, and cystometry in unanesthetized animals. TREK-1 KO animals had an elevated basal muscle tone
Bladder Strength is an advanced combination of ingredients that work together to support normal bladder function and bladder health. It is also recommended for spayed and senior pets to help maintain bladder control. Pumpkin Seed Powder has been used for prostate and bladder health and is beneficial to urinary tract health due to its cleansing action. It also strengthens bladder muscle and supports bladder emptying. Rehmannia glutinosa is a Chinese herb that supports renal function, and healthy levels of estradiol in females and testosterone in males. Wild Yam provides phytoestrogens and relaxes urinary tract muscles. Soy Protein Extract contains isoflavones that provide phytoestrogens to help maintain normal bladder muscle tone that is lost after spaying or due to aging because of lower estrogen levels. Corn Silk Powder contains polysaccharides and mucilage that can help support urinary tract comfort by fortifying mucosal GAG layers. Saw Palmetto Extract helps support normal bladder control and
Bladder irrigation procedure - ACI UROLOGY NETWORK NURSING- BLADDER IRRIGATION. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
Bladder Infection home cures: Chronic Bladder Infections In Women. Bladder Infection, Bladder infection: Symptoms, treatment and prevention.
article{355431f8-a828-40f5-aa88-02a4363356c0, abstract = {,p,Objective: To describe the clinical and ultrasound characteristics of urinary bladder malignancies diagnosed on transvaginal ultrasound in women presenting with suspected gynecological problems. Methods: This was a multicenter retrospective study of women with a histological diagnosis of urinary bladder malignancy that was suspected on transvaginal ultrasound examination. The cases were collected from three centers that specialize in the use of pelvic ultrasound and had been examined between January 2007 and October 2018. Clinical data were obtained from the computer databases and all tumor images were assessed by two of the authors (D.J. and J.K.) to identify characteristic sonographic patterns. We compared the characteristics of tumors between women presenting with symptoms suspicious of urinary bladder malignancy and those without such symptoms. Results: Thirty women with a confirmed diagnosis of urinary bladder malignancy on ...
TY - JOUR. T1 - De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis. AU - Thorson, Willa. AU - Diaz-Horta, Oscar. AU - Foster, Joseph. AU - Spiliopoulos, Michail. AU - Quintero, Ruben A.. AU - Farooq, Amjad. AU - Blanton, Susan. AU - Tekin, Mustafa. PY - 2014/6. Y1 - 2014/6. N2 - Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is characterized by prenatal-onset distended urinary bladder with functional intestinal obstruction, requiring extensive surgical intervention for survival. While it is believed to be an autosomal recessive disorder, most cases are sporadic. Through whole-exome sequencing in a child with MMIHS, we identified a de novo mutation, p.R178L, in the gene encoding the smooth muscle gamma-2 actin, ACTG2. We subsequently detected another de novo ACTG2 mutation, p.R178C, in an additional child with MMIHS. Actg2 transcripts were primarily found in murine urinary bladder and intestinal tissues. Structural analysis ...
Aspects of the relationships between cellular composition and transepithelial sodium transport across toad urinary bladder are reviewed. Changes in cellular sodium produced by amiloride, vasopressin,
Patients with spina bifida and a neurogenic bladder have traditionally been managed with clean intermittent catheterization and pharmacotherapy in order to treat abnormal bladder wall dynamics, protect the upper urinary tract from damage, and achieve urinary continence. However, some patients will fail this therapy and require surgical reconstruction in the form of bladder augmentation surgery using reconfigured intestine or stomach to increase the bladder capacity while reducing the internal storage pressure. Despite functional success of bladder augmentation in achieving a low pressure reservoir, there are several associated complications of this operation and patients do not have the ability to volitionally void. For these reasons, alternative treatments have been sought. Two exciting alternative approaches that are currently being investigated are tissue engineering and neuromodulation. Tissue engineering aims to create new bladder tissue for replacement purposes with both seeded and ...
This study could be criticized because heart rate was uncontrolled by cardiac pacing and the rate-pressure product was not held constant during the study. Although the patients were not paced during bladder distention, the degrees of changes in the rate-pressure product between the two groups were similar. Thus, the changes in the rate-pressure product could not be a major factor of vasoconstriction during bladder distention.. Another limitation of the present study was a lack of normal control data for ethical reasons. The invasive nature of the study made it impractical to have a normal control group. Instead, each patient serves as his or her own control.. The third limitation of the present study was the poor sensitivity of the surface ECG to detect myocardial ischemic during bladder distention. Sutton et al. (34) reported on the electrical focus, causing the ST segment changes to be a localized area of myocardium, and therefore may not be apparent on the leads of a surface ECG. Besides, the ...
Jan. 16, 2007 [Note to Editors: This release about a UI clinical study was last distributed Oct. 16, 2006. Participants still are welcome to participate in the study.]. UI Study Seeks Adults With Urinary Frequency, Painful Bladder Problems. Men and women age 18 and older with certain urinary frequency and bladder problems are invited to participate in a University of Iowa research study on interstitial cystitis and painful bladder syndrome.. The study will compare the safety and effectiveness of an investigational medication to placebo (inactive substance) in reducing symptoms. Interstitial cystitis is a chronic, painful inflammatory condition of the bladder wall. An estimated 10 million people in the United States are affected by interstitial cystitis and painful bladder syndrome.. People with increased daytime and nighttime urinary frequency who have never sought treatment are eligible to participate. Individuals also eligible to participate are people who have not yet received treatment for ...
There are many causes of overactive bladder. Symptoms of overactive bladder occur when there is abnormal increase in sensitivity of the bladder or decreased ability of the bladder to store urine. OAB can also be caused by abnormal sudden, involuntary contraction of the detrusor muscle in the wall of the bladder, which in turn causes you to void. The muscle seems to be twitchy, and its this hyper-reactivity of detrusor muscle in the bladder wall that causes you to feel you need to pee frequently and urgently even when the bladder is not full.. But life doesnt have to be this way! Doctors at the New York Urology Specialists are here to help you change that.. Fortunately, there are many treatments, and one of them is with Botox for overactive bladder. ...
Functions like filling, storing, and emptying the bladder are regulated by nerves. When these nerves become damaged, nerve signals are disrupted and loss of bladder control results.. Neurogenic bladder is often caused by an injury, tumor, or defect of the central nervous system (the brain and spinal cord). Diseases like cerebral palsy, multiple sclerosis, and neural tube defects like spina bifida also can be responsible. Sometimes nerve damage due to heavy, long-term alcohol use, diabetes, or a slipped disk will cause the problem.. Symptoms of neurogenic bladder may include frequent urination (peeing), inability to fully empty the bladder, incontinence (the accidental release of urine), and urinary retention (inability to urinate). People with the disorder are also more likely to develop urinary tract infections (UTIs).. Treatment for neurogenic bladder might include medication, strengthening exercises, or the use of a urinary catheter. Some people will need surgery to help ease symptoms.. ...
Urinary bladder cancer in cats is characterized by an abnormal growth of cells within the urinary bladder. The most common type urinary bladder cancer seen in cats is rooted from a tumor called transitional cell carcinoma (TCC).
As a research subject, the biomechanics of the urinary bladder are relatively young, yet medical problems associated with them are as old as mankind. Offering an update on recent achievements in the field, the authors highlight the underlying biological, chemical and physical processes of bladder function and present the systematic development of a mathematical model of the organ as a thin, soft biological shell. The book will be a valuable resource for postgraduate students and researchers interested in the applications of computational mathematics and solid mechanics to modern problems in biomedical engineering and medicine.
Neurogenic bladder is a condition that can develop in men and women in which the nerves that govern the urinary system and signal when urine should be held in or released from the bladder do not function properly, and patients lose bladder control. The bladder can become either overactive or underactive, depending on the origin of the problem. People can develop neurogenic bladder following trauma such as a spinal cord injury or diseases that affect the nervous system, diabetes, acute infections, genetic nerve problems, or heavy metal poisoning.
Chen B, Zhang H, Liu L, et al. PK2/PKR1 Signaling Regulates Bladder Function And Sensation In Rats With Cyclophosphamide-Induced Cystitis[J]. Mediators of Inflammation, 2015.
Bladder infection is known by its medical term as cystitis. It is one of the most common diseases affecting about six million women each day and ranks second as the common reason for patient visits. Also known as urinary tract infection, this occurs whenever E.coli bacteria are present in the urinary tract passing through the urethra. Women are most likely to have the disease than men because of the structure of their urinary system and the proximity of the rectum to the urethra.. Symptoms of bladder infection may range from mild to severe and some even disappear without need of a treatment. Most of the time, symptoms of bladder infection may be similar to having kidney problems.. Primarily though, symptoms of bladder infection usually relate to the urinary function. Nevertheless, here is a closer look at the different symptoms of bladder infection among women.. ...
Carcinoma of the urinary bladder is a common (in the USA it is the fifth most common form of cancer in males and tenth most common form of cancer in females) malignan- cy and one in which noninvasive staging by imaging plays such an important role. This book presents a complete approach to MR imaging of carcinoma of the urinary bladder from a detailed discussion of the value of MRI in the diagnosis of the urinary bladder to the history of the procedure. The technical discussion of the general principles of MRI including the optimal pulse sequences to be used and factors that influence the quality of images are included in this book. The safety factors are also presented along with contraindications. The application of a double surface coil with the field strength of O.5T provides the fine quality of the illustrations. The atlas of comparative anatomy by MRI on normal volunteers and post-mortem specimens as well as MR images on patients with bladder tumors and post-surgery specimens is unique. The
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Neurogenic bladder is bladder dysfunction that may be either flaccid or spastic. Neurogenic Bladder is caused by neurological damage. More about Neurogenic Bladder.
Purpose: The objectives of this study were to compare the functional expression of muscarinic and purinergic receptors in the urinary bladder of 2 species, rat and guinea pig under comparable experimental conditions; and to test whether the receptors in males and females differ. Methods: Reverse transcription-polymerase chain reaction (RT-PCR) techniques were used to identify gene expression profiles in bladder smooth muscle (total n=8 rats, 7 guinea pigs) and mechanical responses to nerve stimulation and applied acetylcholine (ACh) in the presence of specific antagonists were used to identify functional receptor sub-types (total n=12 rats, 16 guinea pigs). Results: RT-PCR indicated that M2 and M3 were the predominant muscarinic receptor genes in both the male and female rat and guinea pig bladders. The phasic component of the nerve-induced contraction was greater in guinea pigs vs. rats. The tonic component and the ACh response were inhibited by the M3 receptor antagonist, darifenacin (10-6 M, ...
TY - JOUR. T1 - Survival of patients with carcinoma in situ of the urinary bladder. AU - Cheng, Liang. AU - Cheville, John C.. AU - Neumann, Roxann M.. AU - Leibovich, Bradley C.. AU - Egan, Kathleen S.. AU - Spotts, Bruce E.. AU - Bostwick, David G.. N1 - Copyright: Copyright 2007 Elsevier B.V., All rights reserved.. PY - 1999/6/1. Y1 - 1999/6/1. N2 - BACKGROUND. To the authors knowledge, the long term follow-up of patients with carcinoma in situ of the urinary bladder is limited. METHODS. The authors studied 138 patients diagnosed with urothelial carcinoma in situ of the bladder at the Mayo Clinic between 1972-1979. All the histologic slides were reviewed and fulfilled the diagnostic criteria for carcinoma in situ according to the newly proposed World Health Organization and International Society of Urologic Pathology classification system. None of these patients had previous or coexisting invasive urothelial carcinoma at the time of diagnosis. Cox proportional hazards models were used to ...
It has been reported that, under physiological conditions, bladder distention by NS infusion primarily activates nonnociceptive bladder Aδ-afferent fibers, which trigger supraspinal micturition. However, under pathological conditions, bladder irritation by AA infusion activates nociceptive C-afferent fibers, which induce a spinal micturition reflex [15]. In this study, AA induced overactivity and reduced BC compared with the NS control levels (Figs. 4, 5). The sacral nerve was activated by electrical stimulation over a range of frequencies so that frequency response curves could be compared (Figs. 4, 5). We found that SNM at the 5-Hz frequency did not significantly change the BC, while SNM at the 15-, 30-, and 50-Hz frequencies significantly increased the BC during AA infusion. Moreover, no significant differences were observed in the results obtained using those 3 frequencies. This indicates that stimulation at 15 Hz seems to be sufficient to inhibit bladder activity. SNM is not ...
OAB is defined by urgency with or without urinary frequency [11,12]. In other words, urgency is a key symptom of OAB, which is associated with the appearance of DO in urodynamic studies [11]. This has serious implications for patients daily life and quality of life, so it is known that treatment to suppress DO is clinically necessary [13-15]. However, interestingly, the present study using direct gene expression microarray technology found that the bladders in which DO persisted after BOO and deobstruction showed near-normal patterns of gene expression changes. In contrast, the bladders without DO after BOO and deobstruction showed much poorer changes in gene alteration, and continued to have abnormal bladder function. They showed much more dramatically changed gene expression patterns than were found in the BOO group, and a meaningful RV, indicating functional deterioration, even though they showed a significantly reduced RV compared to the BOO group.. The above findings imply that DO does not ...
Bladder relaxation - Prostate Cancer | Medscape. Flotrol promotes bladder contol for overactive bladders. Dont let your bladder dictate your schedule - take control with the Flotrol Natural Bladder Support supplement.
Unlike the urinary bladder of vertebrates, the urinary bladder of crustaceans both stores and modifies urine. The bladder ... A bladder ultrasound may be conducted to view how much urine is within the bladder, indicating urinary retention. A urinary ... Turtles have two or more accessory urinary bladders, located lateral to the neck of the urinary bladder and dorsal to the pubis ... Wikimedia Commons has media related to Urinary bladder. Anatomy photo: Urinary/mammal/bladder/bladder1 - Comparative Organology ...
... includes urinary bladder inflammation such as cystitis, bladder rupture and bladder obstruction ( ... Bladder rupture (rupture of bladder, N32.4) may occur if the bladder is overfilled and not emptied. This can occur in the case ... Ultrasound showing bladder rupture - Week 1 Ultrasound showing bladder rupture - Week 2 Bladder tamponade is obstruction of the ... Underactive bladder Overactive bladder Meijlink, Jane M (April 2014). "Interstitial cystitis and the painful bladder: A brief ...
These artificial bladders worked well for almost a year in the dogs. In 2000, a new procedure for creating artificial bladders ... Replacement can be done with an artificial urinary bladder, an artificial organ.[citation needed] On January 30, 1999, ... "Bladder tissue-engineering: a new practical solution?".(subscription required) Doctors Create Re-Engineered Bladders (Voice of ... The two main methods for replacing bladder function involve either redirecting urine flow or replacing the bladder in situ. ...
... the urinary bladder signals the brain of its need to empty. The signals become stronger as the bladder continues to fill. ... The trigone (a.k.a. vesical trigone) is a smooth triangular region of the internal urinary bladder formed by the two ureteric ... Anatomy photo:44:04-0203 at the SUNY Downstate Medical Center - "The Male Pelvis: The Urinary Bladder" (Articles needing ... Embryologically, the trigone of the bladder is derived from the caudal end of mesonephric ducts, which is of mesodermal origin ...
As distinct from the Western medical concept of urinary bladder, this concept from traditional Chinese medicine is more a way ... Fluids are still sent from the small intestine to the bladder for storage, but the bladder's capabilities are dependent on the ... As opposed to western medicine, where the bladders function is the storage and excretion of urine, the bladder in traditional ... See Zang Fu theory) The Bladder is a Yang (Fu) organ; its paired Yin (Zang) organ is the Kidney. Both are associated with the ...
The urinary bladder is formed partly from the endodermal cloaca and partly from the ends of the Wolffian ducts. In other words ... 4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. ... and these give rise to the trigone of urinary bladder and part of the prostatic urethra. The remainder of the vesico-urethral ... and opens independently into the part of the cloaca which ultimately becomes the urinary bladder. The renal tubules become ...
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. ... and these give rise to the trigone of urinary bladder and part of the prostatic urethra. The remainder of the vesico-urethral ... Due to its large overlap with development of the urinary system, the two systems are typically described together as the ... portion forms the body of the bladder and part of the prostatic urethra; its apex is prolonged to the umbilicus as a narrow ...
Conversely, about 40% to 70% of urinary incontinence is due to overactive bladder. Overactive bladder is not life-threatening, ... and Bristol Female Lower Urinary Tract Symptoms (BFLUTS). Overactive bladder questionnaires include: Overactive Bladder ... Overactive bladder is characterized by a group of four symptoms: urgency, urinary frequency, nocturia, and urge incontinence. ... "Urinary Bladder, Overactive". Retrieved 1 June 2015. Ghosh, Amit K. (2008). Mayo Clinic internal medicine concise textbook. ...
In addition, he was Founding Director of the NCI-funded National Urinary Bladder Flow Cytometry Network which established ... urinary bladder flow cytometry; image analysis; holographic microscopy; robotic telepathology; quantitative ... "Changes in Plasma Membrane Structure Associated with Malignant Transformation in Human Urinary Bladder Epithelium". Cancer ... which qualified patients for inclusion in urinary bladder cancer clinical trials. ...
Bleisch VR, Konikov NF (October 1952). "Malakoplakia of urinary bladder; report of four cases and discussion of etiology". AMA ... bladder, adrenal gland, abdomen and muscle. Telling apart clinically a XP from a tumor condition can be challenging as pointed ...
Primary urinary tract EMZLs of the urinary bladder and kidney are extremely rare but the most common forms of lymphoma that are ... inflammation of the bladder due to urinary tract infection or other causes. Presenting symptoms of primary bladder lymphoma ... Venyo AK (2014). "Lymphoma of the urinary bladder". Advances in Urology. 2014: 327917. doi:10.1155/2014/327917. PMC 3912819. ... Treatment of primary bladder EMZL depends on the extent of disease. Localized disease should be confirmed using, e.g. Positron ...
doi:10.1016/S0035-9203(13)90046-8. Box, C. R. (1914). "Hypertrophied and Dilated Urinary Bladder". Proceedings of the Royal ... Box, C. R.; Pardoe, J.; Parkinson, J. P. (15 October 1910). "Discussion on Infections of the Urinary Tract by Bacillus coli in ...
Urinary tract: Ureters, urinary bladder, urethra. Radical prostatectomy and radical cystectomy both require anastomosis of the ... Urinary diversion Vilhjalmsson, Dadi; Olofsson, Per; Syk, Ingvar; Thorlacius, Henrik; Grönberg, Anders (2015). "The Compression ... bladder to the urethra in order to restore continuity. Microsurgery: The advent of microsurgical technique allowed anastomoses ...
Lewin, Richard J.; Dillard, George V.; Porter, Robert W. (1967). "Extrapyramidal inhibition of the urinary bladder". Brain ...
Brosman, SA (1991). "BCG vaccine in urinary bladder cancer". West J Med. 155 (6): 633. PMC 1003114. PMID 1812634. Gradmann, ...
Long and slender gall bladder. The kidneys rounder than in humans, and the ureters are different. Longer urinary bladder No ...
If the urinary bladder is the subject of interest, a person will be asked to pass urine and the amount of urine left in the ... Ultrasound of the urinary tract involves the use of an ultrasound probe to image parts of the urinary tract. The urinary tract ... Determination of how much urine is in the bladder, for example to assess for urinary retention. To look for evidence and the ... bladder may be recorded. For imaging of the urinary tract it may involve: Assessment of the urinary tract for abnormalities ...
Lewis, S. A.; Diamond, J. M. (1975). "Active sodium transport by mammalian urinary bladder". Nature. 253 (5494): 747-748. ... and degradation of sodium channels in rabbit urinary bladder". Science. 221 (4617): 1288-1290. Bibcode:1983Sci...221.1288L. doi ...
Another example occurs in the urinary bladder. Intestinal metaplasia Squamous metaplasia Micrograph of Barrett's esophagus, an ... Ward AM (July 1971). "Glandular metaplasia and mucin production in transitional cell carcinomas of bladder". J. Clin. Pathol. ...
A Description of the Human Urinary Bladder ... [together with] Animadversions on Lithontriptic Medicines, particularly those of ...
Meesa IR, Junewick JJ (August 2008). "Pelvic plexiform neurofibroma involving the urinary bladder". Pediatric Radiology. 38 (8 ... A 14-year-old girl with NF1 was diagnosed with a neurofibroma involving her bladder, a rare location. Once a plexiform ...
Intravesical infusion is into the urinary bladder. Intravitreal, through the eye. Subcutaneous (under the skin). This generally ...
Transporting point of SI: Urinary Bladder 27. Conception vessel - anterior midline from perineum to lower lip. This is also the ... The turbid is sent downwards to the large intestine, while the useless water is infused to the bladder. The disorders of the ... manifesting stool and urinary disturbance, such as abdominal pain, diarrhea, scanty urine, etc. The Small intestine and its ...
Iannaccone PM, Galat V, Bury MI, Ma YC, Sharma AK (January 2018). "The utility of stem cells in pediatric urinary bladder ... The two main methods for replacing bladder function involve either redirecting urine flow or replacing the bladder in situ. ... Standard methods for replacing the bladder involve fashioning a bladder-like pouch from intestinal tissue. As of 2017 methods ... Tissue Engineering of Urinary Bladder; We Still Have a Long Way to Go?". Stem Cells Translational Medicine. 6 (11): 2033-2043. ...
Shehata R (1976). "The arterial supply of the urinary bladder". Acta Anatomica. 96 (1): 128-134. doi:10.1159/000144666. PMID ... They supply the bladder and terminal ureter. The two most prominent are the superior vesical artery and the inferior vesical ... Andersson KE, Boedtkjer DB, Forman A (January 2017). "The link between vascular dysfunction, bladder ischemia, and aging ... bladder dysfunction". Therapeutic Advances in Urology. 9 (1): 11-27. doi:10.1177/1756287216675778. PMC 5167073. PMID 28042309. ...
Janis C. Kelly (26 October 2015). "Urinary Biomarkers Not Useful for Bladder Cancer Diagnosis". Medscape. Retrieved 31 December ... for its bladder cancer tests. Pacific Edge's suite of tests for bladder cancer are called CxBladder, with specialist subtype ... "Warning over bladder cancer test". Stuff.co.nz. Retrieved 31 December 2015. "Pacific Edge sales up; still no profit". Otago ... Pacific Edge Limited is a cancer diagnostics New Zealand company that offers a genetic biomarker based suite of bladder cancer ...
Cystectomy is the removal of the urinary bladder. It also means removal of a cyst. Corpectomy is the removal of a vertebral ... Hemicorporectomy is the surgical amputation of the entire body below the waist, including the legs, genitalia, urinary system, ...
Smith, Z., Sehgal, S., Van Arsdalen, K. and Goldstein, I. (2014). Placenta Percreta With Invasion into the Urinary Bladder. ...
... (also pig's bladder) is the urinary bladder of a domestic pig, similar to the human urinary bladder. Today, this ... Artificial urinary bladder Balloon Bladder pipe Bumbass Rubber chicken Terry Dicks German cuisine Spanish cuisine The medical ... Historically the pig bladder was used in sports, as the airtight membrane ("bladder") inside a football. In the early 19th ... Pigs, Pork, Offal, Urinary system, Urinary bladder). ... The bladder is used as a casing for several traditional food ...
Andersson KE, Arner A (2004). "Urinary bladder contraction and relaxation: physiology and pathophysiology". Physiol. Rev. 84 (3 ...
... followed by genito-urinary symptoms (9%): both men and women often experience urgency, frequency, incomplete bladder emptying, ... resulting in dizziness or fainting upon standing up urinary incontinence or urinary retention impotence constipation vocal cord ... The most common causes of death are sudden death and death caused by infections, which include urinary catheterization ... dry mouth and urinary retention and incontinence. Palsy of the vocal cords is an important and sometimes initial clinical ...
Urinary incontinence is not unusual after childbirth but it is more common after an instrument delivery. Certain exercises and ... The pregnant woman may then find breathing easier, since her lungs have more room for expansion, but pressure on her bladder ... urinary incontinence, painful sex or severe vaginal/perineal trauma after birth. In cases of a head first-presenting first twin ...
Bmf and Bcl-G is rare in transitional cell carcinomas of the urinary bladder". Pathology. 38 (1): 33-4. doi:10.1080/ ...
Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor and occurs mainly ... April 2013). "Long-term survival of a patient with invasive signet-ring cell carcinoma of the urinary bladder managed by ... urinary bladder, and pancreas. SRCCs do not normally form in the lungs, though a few instances have been reported.[1] Among ... "Metastatic signet-ring cell carcinoma of the urinary bladder: A novel management approach to a rare tumour". Canadian ...
Larger bags are the inner bladder of a Bag-in-box, sometimes used for institutional dispensing. Small individual containers of ... "Polycarbonate Bottle Use and Urinary Bisphenol A Concentrations". Environ Health Perspect. 117 (9): 1368-1372. doi:10.1289/ehp. ...
After penetrating the skin and eventually traveling to the intestines or the urinary tract, the parasite lays eggs and infects ... It damages the intestines, bladder, and other organs and can lead to anemia and protein-energy deficiency. Along with malaria, ... or between the bladder and vagina (see vesicovaginal fistula) after severe or failed childbirth, when adequate medical care is ...
It presents as urinary incontinence. Its impact on women is to reduce the "quality of life dramatically." A ureterovaginal ... and bladder. Radiographic imaging can assist clinicians in identifying the abnormality. A Ureterovaginal fistula is always ... Birth injuries that result in the formation of fistulas and urinary and fecal incontinence have been found to be strongly ...
Menstrual flow from the bladder only without urinary incontinence II - Menstrual flow from both the bladder and vagina with ... The bladder is catheterised for a period of 4 to 8 weeks in order to allow spontaneous closure of the vesicouterine fistula. ... Surgery can be carried out through the vagina, bladder or peritoneum and can be done via laparoscopic or robotic surgery. ... The diagnosis of a vesicouterine fistula is made by demonstrating an abnormal connection between the cavities of the bladder ...
Coniine is toxic for the kidneys because it leads to the constriction of the urinary bladder sphincter and eventually the ...
93%: Roosevelt's prolonged bladder and bowel dysfunction are rare in paralytic polio, since polioviruses do not attack ... He faced many life-threatening medical problems including the possibility of respiratory failure, urinary tract infection, ... The arms were weak; the bladder was paralyzed; the left thumb indicated atrophy. Roosevelt could not stand or walk, and Lovett ... His main symptoms were fever; symmetric, ascending paralysis; facial paralysis; bowel and bladder dysfunction; numbness and ...
"Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder". European Journal of ...
It is sometimes abbreviated to AXR, or KUB (for kidneys, ureters, and urinary bladder). In children, abdominal x-ray is ... Kidneys, ureters, and bladder imaging: plain films of the abdomen. Updated 27 Aug 2015. (Articles with short description, Short ... The projection includes the entire urinary system, from the pubic symphysis to the superior aspects of the kidneys. The ... The abdominal organs included on the xray are the liver, spleen, stomach, intestines, pancreas, kidneys, and bladder. KUB ...
... and finally into the urinary bladder via the ureter.: 406-407 The juxtaglomerular apparatus (JGA) is a specialized region ... The glomerular filtrate leaves the Bowman's capsule at the renal tubule at the urinary pole. The glomerulus is the network ... 67 Because it has a different origin during the development of the urinary and reproductive organs than the rest of the nephron ...
The seminal vesicles are a pair of glands in males that are positioned below the urinary bladder and at the end of the vasa ... They lie in the space between the bladder and the rectum; the bladder and prostate lie in front, the tip of the ureter as it ... The Urinary Bladder" Anatomy photo:44:08-0103 at the SUNY Downstate Medical Center - "The Male Pelvis: Structures Located ... are a pair of two convoluted tubular glands that lie behind the urinary bladder of some male mammals. They secrete fluid that ...
If this fascia falls, the ipsilateral side of the vagina falls, carrying with it the bladder and the urethra, and thus ... contributing to urinary incontinence. Loukas, Marios; Carmichael, Stephen W.; Colborn, Gene L. (2009). Gray's Anatomy Review. p ...
... urinary bladder, lung, breast, fallopian tubes, and the pancreas. This disease is often discovered during surgery for other ...
... injecting botox into the bladder wall to target bladder nerves for treating urinary incontinence due to an overactive bladder ... Bladder injections for refractory overactive bladder". In Smith, Arthur D.; Preminger, Glenn; Badlani, Gopal H.; Kavoussi, ... following a course of capsaicin instillation into the bladder in managing urinary incontinence due to an overactive bladder. In ... where they developed an outpatient procedure for treating urinary incontinence in people with an overactive bladder that did ...
... urethral strictures or post-operative urinary retention, need to be continuously catheterised to empty their urinary bladders. ... People with neurogenic bladder disorders like spinal cord injury, spina bifida or multiple sclerosis, and non-neurogenic ... a medical technique used in conditions where patients need either short-term catheter-based management of the urinary bladder ... But such continuous catheterization can lead to problems like urinary tract infections (UTI), urethral strictures or male ...
Wallace, Sheila A; Roe, Brenda; Williams, Kate; Palmer, Mary (26 January 2004). "Bladder training for urinary incontinence in ... This not only holds up the bladder but also compresses the bottom of the bladder and the top of the urethra, further preventing ... Stress incontinence, also known as stress urinary incontinence (SUI) or effort incontinence is a form of urinary incontinence. ... Pelvic organ prolapse Artificial urinary sphincter Urinary incontinence Pelvic floor Kegel Exercises Ghoniem, G. M.; Elgamasy, ...
... urinary retention, waking at night to urinate, increased urinary frequency and urgency, and over- or underactive bladder) ... Urinary difficulty is one of the earliest symptoms with multiple system atrophy, and is often severe. Corticobasal syndrome, ... Muscarinic antagonists used for urinary symptoms might worsen cognitive impairment in people with Lewy body dementias. There is ... Medications (including tricyclic antidepressants and treatments for urinary incontinence) with anticholinergic properties that ...
Symptoms may include lower urinary tract symptoms associated with stenosis of the urethra, painful sexual intercourse, and ... bladder and conjunctiva of the eyes. Lichen planus lesions can occur in many different forms: Occasionally, lichen planus is ...
... urinary incontinence and neurogenic bladder." "aagus.org". aagus.org. Retrieved January 21, 2013. "sbur.org". sbur.org. ... Authors Brubaker L, Chiang S, Zyczynski H, Norton P, Kalinoski DL, Stoddard A, Kusek JW, Steers, William D.; Urinary ... and chaired the National Institutes of Health's urinary incontinence and interstitial cystitis clinical trial groups. In 2011, ... Association of Genitourinary Surgeons Society for Basic Urologic Research Solifenacin treatment in men with overactive bladder ...
More than a third of urinary bladder SCCs express p16. SCCs of urinary bladder express p16 independent of gender. p16 ... "Hypermethylation of p16 and DAPK promoter gene regions in patients with non-invasive urinary bladder cancer". Archives of ... expression alone cannot be used to discriminate between SCCs arising from uterine cervix versus urinary bladder. Concentrations ... "P16 expression in squamous cell carcinomas of cervix and bladder". Applied Immunohistochemistry & Molecular Morphology. 18 (4 ...
... rarely cancers of the alimentary tract and urinary bladder); possibly responsible for the skin tumour equine sarcoid in horses ...
Cystoscopy shows the urinary tract from inside the bladder, using a thin, flexible camera tube inserted in the urethra. ... The prostate surrounds the urethra, a muscular tube that closes the urinary bladder. Any of the mentioned reasons can lead to ... Samuel David Gross (1851). A Practical Treatise On the Diseases and Injuries of the Urinary Bladder, the Prostate Gland, and ... Bauer RM (2016). "Urinary Dysfunction in Prostate Cancer: Male Slings". In Sandhu JS (ed.). Urinary Dysfunction in Prostate ...
It is the surgical intervention for both cystocele (protrusion of the urinary bladder into the vagina) and rectocele ( ...
Urinary bladder conditions: bladder incontinence or urine retention Gastrointestinal tract: dysphagia, abdominal pain, nausea, ... but common symptoms are poor bladder control, abnormal blood pressure or heart rate, and reduced ability to sweat normally. ... affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the ...
... on Primary Uroepithelial Cells of the Canine Urinary Bladder". Toxicological Sciences. 72 (1): 164-70. doi:10.1093/toxsci/ ...
The urinary bladder, uterus, fallopian tubes, and ovaries may be seen as either abdominal organs or as pelvic organs. Finally, ... The spleen, and organs of the urinary system including the kidneys, and adrenal glands also lie within the abdomen, along with ... The abdomen in vertebrates contains a number of organs belonging to, for instance, the digestive system, urinary system, and ...
Urine enters the bladder from the kidneys through the ureters and is discharged from the body via the urethra. The bladder of ... bladder, urinary, muscular sac located in the pelvis that stores urine and contracts to expel it from the body. Urine enters ... The muscles in the wall of the bladder also contract, forcing urine out through the urethra. The bladder is subject to ... See urinary system. The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2023, Columbia University Press. All rights ...
Cystoscopy is endoscopy of the urinary bladder via the urethra. It may employ either a rigid or a flexible cystoscope and may ... the bladder neck, and both ureteral orifices are identified. The bladder base and the posterior bladder wall are examined, and ... Endoscopy of Urinary Bladder. The patient is positioned on the cystoscopy table, prepared, and draped in the usual sterile ... Urinary infection following out-patient flexible cystoscopy. Br J Urol. 1990 Nov. 66(5):503-5. [QxMD MEDLINE Link]. ...
Background: Urinary bladder cancer is the fourth most common cancer in Jordan. No research on survival from bladder cancer at ... Survival of patients with urinary bladder cancer in Jordan, 2005-2014  Nour Abdo; Majd Alsoukhni; Anwar Batieha; Kamal Arqoub ...
Cystitis (bladder infection) represents the majority of these infections (see the image below). ... Urinary tract infections (UTIs) are common in females, accounting for over 6 million patient visits to physicians per year in ... Urinary Tract Infection (UTI) and Cystitis (Bladder Infection) in Females * Sections Urinary Tract Infection (UTI) and Cystitis ... encoded search term (Urinary Tract Infection (UTI) and Cystitis (Bladder Infection) in Females) and Urinary Tract Infection ( ...
... ... 2018)‎. WHO recommendation on duration of bladder catheterization after surgical repair of simple obstetric urinary fistula. ...
It is now recognized that superficial bladder carcinomas are a heterogenous group of tumors with diverse biological and ... Recognition of diagnostic pitfalls associated with lamina propria invasion is critical for the evaluation of bladder tumor ... This review will discuss recent progress and controversial issues on the staging and substaging of bladder carcinomas. ... Essential elements for handling and reporting of bladder tumor specimens will also be discussed. ...
If urinary acidifiers are being promoted as beneficial to urinary health, the same sort of mistake is occurring. Urinary ... Struvite is the most common type of stone found in the lower urinary tract of dogs (somewhere around 50 to 60% of urinary ... The other signs do point strongly towards bladder or urethral stones. Sometimes it is possible to palpate bladder stones and ... or with stone formation in the bladder or urinary tract. There are a number of possible crystal types and stone compositions ...
encoded search term (Pathology of Urinary Bladder Inverted Papilloma) and Pathology of Urinary Bladder Inverted Papilloma What ... in the development of inverted papilloma of the urinary bladder by evaluating 27 inverted papillomas of the urinary bladder for ... Pathology of Urinary Bladder Inverted Papilloma Updated: May 11, 2021 * Author: Alessia Cimadamore, MD; Chief Editor: Liang ... Sung MT, Eble JN, Wang M, Tan PH, Lopez-Beltran A, Cheng L. Inverted papilloma of the urinary bladder: a molecular genetic ...
... of bladder tumour patients and 59% of controls are slow ac … ... were measured in 228 patients with tumours of the urinary ... bladder and 100 non-cancer controls. 63.6% of the patients and 54.0% of the controls were slow acetylator phenotypes (p less ... N-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population Carcinogenesis. 1985 Feb;6(2):199 ... N-Acetyltransferase phenotypes were measured in 228 patients with tumours of the urinary bladder and 100 non-cancer controls. ...
... Forum. Apis Mellifica, Lycopodium Clavatum and Conium Maculatum are ... burning in urinary bladder & urethra 7. Posts about Cystitis. Interstitial cystitis2Chronic vaginitis with chronic bladder ... cystitis burning in urinary bladder. sir i take cantharis 200 two drops two time in the day from 6 day for cystitis. and now i ... urinary bladder wall thikness and irregular , cystitis. sir i took more medicine but no benefit. sir current i am useing ...
In short-circuited bladders with the M pH lowered to the point of zero net H+ secretion, the rate of HCO3- entry into M in ... In bladders depleted of substrate, pyruvate (5 times 10-3 M) increased the HCO3- flux from 0.36 plus or minus 0.05 to 0.58 plus ... Addition of HCO3- to the serosal side (S) of the isolated turtle bladder results in a HCO3- flow from S to the mucosal side (M ...
Tumor-derived urinary exosomal long non-coding RNAs as diagnostic biomarkers for bladder cancer. ... Transcript levels of lncRNAs in urinary exosomes are potential diagnostic biomarkers in bladder cancer. ... Bladder cancer (BC) is the sixth most common malignancy in men and 17th in women. Exosomal long non-coding RNAs (lncRNAs) have ...
... Aug 31, 2020. News The concept of leaking urine is not new and has ... Here are some conservative estimates of the scope of the problem of urinary incontinence and overactive bladder from the ... This is related to falling of pelvic organs like the bladder and uterus. The urethra, which is the tube from the bladder where ... First, with urinary incontinence it is important to note you are not alone - The problem is significant as UI affects the lives ...
Labels point to the bladder, bladder neck, pubic bone, sling material, and u ... Diagram of side view of female bladder supported by a sling to prevent urinary incontinence. The sling is wrapped around the ... Side view of female bladder supported by a sling to prevent urinary incontinence. View full-sized image Download Media Please ... Diagram of side view of female bladder supported by a sling to prevent urinary incontinence. The sling is wrapped around the ...
Neurogenic Bladder - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version. ... Symptoms of Neurogenic Bladder The primary symptom is urinary incontinence Urinary Incontinence in Adults Urinary incontinence ... People with neurogenic bladder are at risk for urinary tract infections Overview of Urinary Tract Infections (UTIs) In healthy ... When urine remains in the bladder for too long, the person is at risk of urinary tract infections Overview of Urinary Tract ...
... and specific use of the Urinary Bladder 09 (UB 9) acupuncture point. ... Urinary Bladder 01 (UB 1) Urinary Bladder 02 (UB 2) Urinary Bladder 03 (UB 3) Urinary Bladder 04 (UB 4) Urinary Bladder 05 (UB ... Urinary Bladder 06 (UB 6) Urinary Bladder 07 (UB 7) Urinary Bladder 08 (UB 8) Urinary Bladder 09 (UB 9) Urinary Bladder 09 (UB ... Urinary Bladder 10 (UB 10) Urinary Bladder 11 (UB 11) Urinary Bladder 12 (UB 12) Urinary Bladder 13 (UB 13) Urinary Bladder 14 ...
... in urinary bladder tissue. Antibody staining with HPA028252 in immunohistochemistry. ... URINARY BLADDER - Expression summary. Protein expression. Urinary bladderi On the top, protein expression in current human ... SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER ... TISSUE PRIMARY DATA URINARY BLADDER ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS ...
... and the importance of immunohistochemical study in order to define its primary origin from the bladder and choose the most ... We present an uncommon case of mucinous adenocarcinoma of the bladder (MAB) with signet-ring cells extensively infiltrating ... I. Romics, E. Székely, and A. Szendroi, "Signet-ring cell carcinoma arising from the urinary bladder," The Canadian Journal of ... S. Roy and A. V. Parwani, "Adenocarcinoma of the urinary bladder," Archives of Pathology & Laboratory Medicine, vol. 135, no. ...
Urinary bladder cancer is a form of cancer primarily arising in the tissues of the urinary bladder. It is the most common ... Background: Urinary bladder cancer is the fourth most common cancer in Jordan. No research on survival from bladder cancer at ... This was a survival analysis of patients with bladder cancer. All Jordanians with urinary bladder cancer registered in the ... of cancer deaths were due to bladder cancer (4). However, no research on survival from urinary bladder cancer at the national ...
Final diagnosis: Transitional cell carcinoma of the urinary bladder. Thanks to: Dr Kapil Naik, Radiologist Goa, India ... CT elegantly demonstrates the urinary bladder mass along the right wall of the bladder with heterogeneous post-contrast ... Desai P, Transitional cell carcinoma - urinary bladder. Case study, Radiopaedia.org (Accessed on 08 Dec 2022) https://doi.org/ ...
Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes. *Mark ... Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes}}, volume = {{127 ... Unilateral removal of the pelvic ganglion affected the bladder-half on the denervated side more profoundly than that on the non ... Unilateral removal of the pelvic ganglion affected the bladder-half on the denervated side more profoundly than that on the non ...
Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder. ... Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder ... Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder * Share on ... info about Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder ...
The urinary tract infection (UTI) is one of the most common ailments in small animal practices. ...
Urinary tract infection due to herniation of bladder. *. Tetsu Sakamoto, MD Tetsu Sakamoto ... etiologies than bladder hernia, a urologist was consulted to manage the bladder hernia. Surgery was planned but not performed ... He experienced a urinary tract infection (UTI) two months ago. He did not complain of other symptoms, including abdominal or ... Considering the bladder hernia as a trigger for UTI because of the history of recurrent UTI without other ...
Action potential of mouse urinary bladder smooth muscle (Mahapatra et al 2018). ... of mouse urinary bladder smooth muscle. PLOS One (2018) NEURON { SUFFIX CaT USEION ca READ eca WRITE ica VALENCE 2 RANGE gcat, ... which can further shed light on certain aspects of urinary bladder function and dysfunction. Reference: 1 . Mahapatra C, Brain ... A biophysically constrained computational model of the action potential of mouse urinary bladder smooth muscle. PLoS One 13: ...
Urinary bladder length (±0.1 mm) . Urinary bladder width (±0.1 mm) . Initial 401.0±29.1 (284-298) 292±1 (284-298) 48±3 (30-62) ... Urinary bladder length (±0.1 mm) . Urinary bladder width (±0.1 mm) . Initial 401.0±29.1 (284-298) 292±1 (284-298) 48±3 (30-62) ... Adult Gila monsters absorbed water from the urinary bladder into circulation and absorption of water from the urinary bladder ... full urinary bladder (FULL empty; hatched bar),and empty urinary bladder initially (EMT; open bar). Values shown are means± 1 s ...
Aptamer-antibody hybrid ELONA that uses hybridization chain reaction to detect a urinary biomarker EN2 for bladder and prostate ... Aptamer-antibody hybrid ELONA that uses hybridization chain reaction to detect a urinary biomarker EN2 for bladder and prostate ...
To determine the possible effects of microgravity on mucin production in the urinary bladder, we examined the transitional ... epithelium of the urinary bladder from female mice that were flown on the space shuttle Endeavour for 12 days in August, 2007. ... The bladder tissue from the three treatment groups is being qualitatively analyzed for mucin thickness and types of mucins ... Bladder tissue was paraffin embedded, sectioned, mounted, and histologically stained using an Alcian Blue Periodic Acid Schiff ...
Urinary Bladder 54 , Zhi Bian , 秩邊: This acupuncture point, used in traditional Chinese medicine, is located On the level of ... Urinary Bladder 54, Zhi Bian. 秩邊, zhì biān, "Sequential Limit". Is this Acupuncture Point effective in the clinic?. +1 ...
... DSpace/Manakin Repository ...
  • To address the condition of urinary incontinence (UI), I will outline the types of incontinence and testing that are available to assess this wide-scaled problem and preview solutions that range from simple changes in behavior to mediations and or surgery as appropriate. (adventisthealth.org)
  • First, with urinary incontinence it is important to note you are not alone - The problem is significant as UI affects the lives of at least 25% of women over the age of 18. (adventisthealth.org)
  • About 17% of women over 18 years of age have overactive bladder (OAB) and an estimated 12.2 million adults have urge incontinence. (adventisthealth.org)
  • Stress urinary incontinence, the most prevalent form of incontinence among women, affects an estimated 15 million adult women in the U.S. (adventisthealth.org)
  • Approximately, 1 out of 3 women over the age of 45, and 1 out of 2 women over 65 have stress urinary incontinence. (adventisthealth.org)
  • In 2010, 211,000 women had some type of surgery for stress urinary incontinence. (adventisthealth.org)
  • Mixed Incontinence - This is quite common as the injury to the pelvic floor from childbirth and the prolapse that happens will commonly lead to both stress and overactive bladder. (adventisthealth.org)
  • This is roughly 60-70% of all urinary incontinence and as might be expected shows a mixed response to treatments. (adventisthealth.org)
  • Uncontrollable loss of urine (urinary incontinence) is the primary symptom. (msdmanuals.com)
  • Urinary Incontinence in Adults Urinary incontinence is involuntary loss of urine. (msdmanuals.com)
  • Doctors may suspect neurogenic bladder in people with nerve disorders who have incontinence. (msdmanuals.com)
  • Urinary incontinence is associated with enhanced spontaneous phasic contractions of the detrusor smooth muscle (DSM). (yale.edu)
  • Even though the bladder volume was increased by augmentation, the incontinence remained. (kinderradiologie-online.de)
  • Patients report fewer episodes of urinary incontinence and less bother from overactive bladder symptoms. (newyorkurologyspecialists.com)
  • If Ditropan has intolerable side effects or does not help with urinary symptoms, other treatment options for urinary frequency, urgency, urinary incontinence and symptoms of OAB are available. (newyorkurologyspecialists.com)
  • Botox for urinary urgency , frequency and incontinence is also useful for many patients. (newyorkurologyspecialists.com)
  • Retention can almost be seen as the opposite of incontinence - the issue here is incomplete bladder emptying or problems emptying in general. (wellspect.us)
  • At the same time, you may also dribble urine in between voiding, due to an overfull bladder (overflow incontinence). (wellspect.us)
  • Because of these confusing symptoms, chronic retention quite often gets diagnosed as overactive bladder or urge incontinence. (wellspect.us)
  • Eventually, the build-up of urine in the bladder goes over your bladder's capacity to hold it - resulting in urine leakage usually associated with incontinence, as well as potentially dangerous backflow to the kidneys or bladder muscle damage. (wellspect.us)
  • The international Continence Society has defined this problem as a Urinary urgency with or without incontinence. (thaiuroincambodia.com)
  • Darifenacin extended-release tablets is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency and frequency. (nih.gov)
  • What is Urinary Incontinence? (howtowhere.com)
  • Urinary incontinence is characterized by the inability to control the bladder and subsequent involuntary or accidental urine leakage. (howtowhere.com)
  • Urinary incontinence ranges in severity from minor dribbling of urine and bed wetting to complete bladder loss. (howtowhere.com)
  • Women are twice as likely to suffer from urinary incontinence due to side effects of pregnancy, childbirth, and menopause. (howtowhere.com)
  • Though urinary incontinence can happen to anyone at any age group for various reasons, it primarily affects small children and older adults. (howtowhere.com)
  • Stress incontinence- Loss of urine due to physical exertion on the bladder by coughing, sneezing, laughing, lifting heavy weight or exercising, or any activity that increases intra-abdominal pressure. (howtowhere.com)
  • Urge incontinence is commonly caused due to urinary tract infection (UTI). (howtowhere.com)
  • Overflow or overactive bladder incontinence- Frequent urge for urination or constant dribbling of urine due to the overflowing bladder and inability to empty the bladder. (howtowhere.com)
  • Apple Cider Vinegar (ACV) is the best home remedy for urinary incontinence. (howtowhere.com)
  • Additionally, Apple Cider Vinegar makes you lose excess weight, which is another cause of urinary incontinence. (howtowhere.com)
  • A study from Tel Aviv University showed that taking magnesium hydroxide pills twice a day improves women's urinary incontinence. (howtowhere.com)
  • There is a strong link between low vitamin D levels and urinary incontinence. (howtowhere.com)
  • A 2010 study found that women who were 20 years and older and had normal vitamin D levels were less likely to have urinary incontinence. (howtowhere.com)
  • When you experience both Stress and Urge Urinary Incontinence, it's called Mixed Urinary Incontinence. (poise.com)
  • Stress urinary incontinence (SUI) is the most prevalent form of incontinence in women. (medscape.com)
  • Urinary incontinence (UI) is defined by the International Continence Society (ICS) as "the complaint of involuntary loss of urine" (Haylen et al. (medscape.com)
  • Urinary incontinence occurs in both men and women, although it is twice as common in women (Buckley & Lapitan, 2010). (medscape.com)
  • 2013). Stress urinary incontinence (SUI) is the most common form and will be the main focus of this article. (medscape.com)
  • Berries are also used to treat other urinary system conditions, including kidney stones, bladder inflammation, and incontinence. (twigscafe.com)
  • This may be even more important if your doctor has told you that you have Stress Urinary Incontinence (SUI) . (depend.com)
  • Urinary incontinence is the involuntary leakage of urine. (wearable-technologies.com)
  • San Diego, CA-based Triple W has launched its new wearable device for urinary incontinence in the US. (wearable-technologies.com)
  • Objective: To characterize the scientific production related to the impact of urinary incontinence on quality of life of pregnant women. (scirp.org)
  • Conclusion: Urinary incontinence affects the mother's life, resulting in social, behavioral, physical and emotional harm, taking this woman to be excluded from society and feel insecure about their health. (scirp.org)
  • Patients with urinary incontinence or diagnosed overactive bladder before radical prostatectomy. (who.int)
  • Urine enters the bladder from the kidneys through the ureters and is discharged from the body via the urethra . (infoplease.com)
  • When the level of urine reaches about half this amount, pressure of the accumulating fluid stimulates nervous impulses that relax the external sphincter, a muscle that forms a dense band around the urethra at the base of the bladder. (infoplease.com)
  • The muscles in the wall of the bladder also contract, forcing urine out through the urethra. (infoplease.com)
  • The urethra, which is the tube from the bladder where the urine flows, is often kinked like a garden hose and causes the bladder to empty poorly. (adventisthealth.org)
  • The tube that carries urine from the bladder out of the body (urethra) contains no bacteria. (msdmanuals.com)
  • Congenital defect of the front bladder and abdominal wall with free-lying hind bladder wall, the vesical triangle and the hind wall of the urethra. (kinderradiologie-online.de)
  • It may be caused by obstructions in the bladder or urethra (the tube that carries urine from the bladder outside the body), by a disruption of sensory information in the nervous system (e.g. spinal cord or nerve damage), or by swelling of the bladder (e.g. by delaying urination for a long period of time). (wellspect.us)
  • The urethral sphincters are two muscles used to control the exit of urine in the urinary cancer endometrial ecografia through the urethra. (evenimente-corporate.ro)
  • At the same time, the bladder, the sphincter (valve that surrounds the urethra that keeps urine from leaking) and pelvic floor muscles relax, allowing the urine to come out. (karger.com)
  • cutting in bladder extending down urethra, burning pain even after urinating, urine yellow, turbid and flocculent, back lame and sore with pain in loins and hips, all. (hpathy.com)
  • Violent pain in bladder urging to urinate, from smallest quantity of urine, painful discharge of a few drops of bloody urine, causing very sharp pain, as if red hot iron were passing through the urethra. (hpathy.com)
  • Spasmodic pain in the perineum along along the urethra and down the testes, which are drawn up, cutting pains through abdomen, which are distended and painful to touch, especially in bladder. (hpathy.com)
  • burning in the neck of bladder and urethra, pressure on bladder, with frequent ineffectual urging and passing the urine by drops, Frothy dark yellow urine with the odour of violets, swelling and dilation of orifice of urethra. (hpathy.com)
  • Your urinary system includes your two kidneys and the bladder, the tube that connects each kidney to the bladder (ureters), and the tube that carries urine from the bladder to the outside (urethra). (spirehealthcare.com)
  • The urinary system is divided into two regions based on anatomy and function: upper (kidneys and ureters) and lower urinary (urinary bladder and urethra) tracts. (cantonanimalclinic.com)
  • The lower urinary tract serves as a reservoir for urine (bladder) and a pathway for excretion (urethra). (cantonanimalclinic.com)
  • This is a telescopic inspection of the bladder and urethra (water pipe) and it helps us to identify any abnormalities. (kingstonhospital.nhs.uk)
  • To assist us with diagnosing abnormalities of the bladder or urethra or to remove a previously inserted ureteric stent. (kingstonhospital.nhs.uk)
  • Temporary insertion of a urinary catheter (a tube passed up the urethra and into the bladder) to drain urine and blood if bleeding is heavy or you cannot pass urine. (kingstonhospital.nhs.uk)
  • We pass a small telescope into your urethra and up into your bladder to check for any abnormalities. (kingstonhospital.nhs.uk)
  • Background:Urethrocystoscopy is defined as endoscopic visualization of the urethra and the urinary bladder for the purpose of diagnosis or treatment of diseases of the lower urinary tract.Objective: To study the indications, diagnosis and complications of diagnostic urethrocystoscopy in our hospital.Materials and method:It was a retrospective descriptive study of all patients who had diagnostic urethrocystoscopy in our hospital between January 2016 to December 2021. (bvsalud.org)
  • The bladder is subject to infection (commonly called cystitis ) and the formation of stones. (infoplease.com)
  • Nevertheless, according to 2010 guidelines from the American College of Obstetricians and Gynecologists, a urine culture is not required for the initial treatment of women with a symptomatic lower urinary tract infection (UTI) with pyuria or bacteriuria or both. (medscape.com)
  • Stones in the Urinary Tract Stones (calculi) are hard masses that form in the urinary tract and may cause pain, bleeding, or an infection or block of the flow of urine. (msdmanuals.com)
  • He experienced a urinary tract infection (UTI) two months ago. (amjmedsci.com)
  • Here's my experience with colloidal silver …About 2 years ago, I discovered I had a urinary tract infection. (thesilveredge.com)
  • Well, my mother, an amazing woman, and took it upon herself to treat my father and his urinary infection with colloidal silver. (thesilveredge.com)
  • She started giving him 1 oz. a day with his breakfast and would spray the catheter after giving him a shower and wouldn't you know it, his urinary infections went away and he felt much better not having to go through the pain of that awful infection. (thesilveredge.com)
  • I had been trying for about a week to cure a Urinary Tract Infection (UTI) on my own with lots of cranberry juice and water. (thesilveredge.com)
  • When patients come to see Urologist, we will do the completion of history taking, physical examinations, frequency volume chart and also urinalysis to exclude the infection or urinary tract stone cause. (thaiuroincambodia.com)
  • Cystitis is a quite common urinary tract infection, characterized by an inflammation of the bladder, specifically of the wall of the bladder. (evenimente-corporate.ro)
  • Patients with a neurogenic bladder or bladder diverticulum and postmenopausal women with bladder or uterine prolapse have an increased frequency of urinary tract infection because of incomplete bladder emptying. (medscape.com)
  • Lithotripsy is indicated in people with large kidney stones causing pain, urinary tract infection, bleeding, and renal damage. (anglianurology.com)
  • Urinary tract infections occurs frequently among young women with over ¼ having a second infection. (hpathy.com)
  • Uncomplicated urinary tract infection occurs in healthy people. (hpathy.com)
  • Complicated urinary tract infection is associated with anatomical, functional or metabolic anomalies of the urinary tract that disable the natural host defenses and lead to tissue injury. (hpathy.com)
  • We used automated urinalysis with flow cytometry to characterize urine samples from 135 acute KD subjects and 87 febrile control (FC) subjects without urinary tract infection. (lww.com)
  • Damage to the central or peripheral nervous system from infection, trauma, malignancy or vascular insult may also result in a dysfunctional bladder. (bmj.com)
  • No drug resistance developed in blood, but Domergue did detect it in a mouse model of bladder infection that had been developed by collaborator David Johnson of the University of Maryland School of Medicine. (news-medical.net)
  • Urinary infection, requiring treatment with antibiotics. (kingstonhospital.nhs.uk)
  • This can also lead to frequent urinary tract infections. (adventisthealth.org)
  • Overview of Urinary Tract Infections (UTIs) In healthy people, urine in the bladder is sterile-no bacteria or other infectious organisms are present. (msdmanuals.com)
  • Bladder infections and UTIs (i.e., urinary tract infections) can be stubborn and painful, and can often require prescription antibiotic drugs to cure. (thesilveredge.com)
  • A lot of people have reported good results using colloidal silver to help the body defeat stubborn urinary tract infections (UTI). (thesilveredge.com)
  • My elderly mother has struggled with urinary tract infections for years and has had to take antibiotics over and over, but still it came right back. (thesilveredge.com)
  • That was more than a year ago and she has been free of major episodes of urinary tract infections since that time. (thesilveredge.com)
  • The catheter would become infected, resulting in urinary tract infections, and the elderly gentleman had to take antibiotics, until they quit working for him. (thesilveredge.com)
  • As you can see, those are quite different successful experiences in which people used colloidal silver to heal urinary tract infections. (thesilveredge.com)
  • I have had two urinary tract infections in 16 years. (thesilveredge.com)
  • Complicated urinary tract infections (UTIs) occur in the setting of pre-existing metabolic, functional, or structural abnormalities of the urinary tract. (medscape.com)
  • For more information on this topic, see the Medscape Reference article Urinary Tract Infections in Diabetes Mellitus . (medscape.com)
  • It balances out the body's pH level and helps fighting urinary tract infections. (howtowhere.com)
  • Bacteria cause urinary tract infections (UTIs), so doctors usually treat them with antibiotics. (medicalnewstoday.com)
  • Learn more about urinary tract infections here. (medicalnewstoday.com)
  • One study found that drinking 6 ounces of bilberry juice three times daily for four months was an effective treatment for urinary tract infections in women. (twigscafe.com)
  • Depomed, Inc. has received FDA approval for an extended-release formulation of ciprofloxacin hydrochloride (Proquin XR), once-daily, for treatment of uncomplicated urinary tract infections. (urologytimes.com)
  • Cats are inherently resistant to urinary tract infections because they produce highly concentrated urine. (cantonanimalclinic.com)
  • Control of Urination The kidneys constantly produce urine, which flows through two tubes (the ureters) to the bladder, where urine is stored (see figure Viewing the Urinary Tract). (msdmanuals.com)
  • when urine retained in the bladder causes urine to back up in the kidneys. (msdmanuals.com)
  • Inflammation in the urinary tract can occur when bacteria causes inflammation from the kidneys to the bladder to the urinary tract. (drfrancescott.com)
  • I believe also that kidneys and urinary system are constantly subjected to eliminating toxins that the body breaks down so supporting the urinary system is important.The first priority is to eliminate the toxins and bacteria to reduce the inflammation. (drfrancescott.com)
  • A tube is inserted through the bladder or back into the kidney to help drain urine from the kidneys until all the tiny fragments of stone pass out of the body through urine. (anglianurology.com)
  • Each day, the kidneys empty about 1.5 litres (3 pints) of urine into the bladder. (karger.com)
  • In urinary schistosomiasis, there is progressive damage to the bladder, ureters and kidneys. (who.int)
  • sir i have cystitis & burning inflammation in urinary bladder before passing urine and urine come pressure and pass hardly.when pass urine then give sourse and pass urine weaky as drop by drop. (abchomeopathy.com)
  • Electrical impedance spectroscopy (EIS) in the urinary bladder: the effect of inflammation and edema on identification of malignancy. (ox.ac.uk)
  • Reducing consumption of acidic foods and drinks like tomatoes, onions, citrus fruits, wine, soft drinks and coffee can be unrealistic when you consider the typical American diet, so Prelief has been of real help for many who suffer bladder inflammation and the resulting leakage. (depend.com)
  • Significant urinary tract inflammation can occur to cause life threatening urinary tract obstruction. (cantonanimalclinic.com)
  • A moderate wall thickening of the bladder and a mild dilatation of the proximal portion of the ureters bilaterally were also evident. (hindawi.com)
  • Like the ureters, the bladder is composed of four concentric layers. (histologyguide.com)
  • The urethral epithelium is composed of stratified squamous cells, which variably becomes transitional as the bladder is approached. (medscape.com)
  • The medial pubovisceral portion of the levator ani complex also is a major contributor to active bladder neck and urethral closure in similar situations. (medscape.com)
  • Invasive treatments, including urethral bulking agents, bladder neck colposuspension, and sling procedures, should be considered once conservative measures have failed. (medscape.com)
  • Thankfully, there are a number of natural health products that can also aid the body in healing stubborn UTIs or bladder infections, and colloidal silver is one of them. (thesilveredge.com)
  • I wanted to let you know, that when my father was still living, he was getting quite a few urinary infections and the doctors just kept on giving him more antibiotics that were not working. (thesilveredge.com)
  • C. glabrata and its cousin C. albicans cause infections in blood and in mucosal tissues such as the urinary tract and vagina. (news-medical.net)
  • C. glabrata is the second leading cause (behind C. albicans) of yeast infections, or candidiasis, in people with urinary catheters. (news-medical.net)
  • Methods: Using immunohistochemistry, we evaluated the IGFBP-5 expression status and its associations with clinicopathological features and survival in 340 cases of upper urinary tract urothelial carcinoma (UTUC) and 295 cases of UBUC. (elsevier.com)
  • Comparison of voided versus catheter-collected urine samples indicated an origin of the cells from the bladder or upper urinary tract in both patient groups. (lww.com)
  • The upper urinary tract filters metabolic wastes from the blood to be excreted into the urine. (cantonanimalclinic.com)
  • Bladder distention in patient with interstitial cystitis. (medscape.com)
  • When E. coli reaches the bladder, it invades the mucosal bladder wall, which causes the body to produce cystitis, an inflammatory reaction. (medicalnewstoday.com)
  • by Dr. Alex Shteynshlyuger , a board-certified urologist, and specialist in the treatment of urinary problems in men and women including frequent urination, burning with urination and urinary retention. (newyorkurologyspecialists.com)
  • The shorter distance to the bladder in females makes it easy for the bacteria to reach the bladder even before they are removed by urination. (hpathy.com)
  • great irritation at the neck of bladder, with frequent and burning urination. (hpathy.com)
  • severe and dull pain in bladder, not abating after urination, with tenderness on pressure and soreness, of testicles and cords. (hpathy.com)
  • Bladder catheterization, imaging, and tests to measure urine flow are done. (msdmanuals.com)
  • Treatment is aimed at periodic emptying of the bladder (for example, by intermittent catheterization and/or drugs). (msdmanuals.com)
  • Treatment is draining the bladder of urine with intermittent self-catheterization along with treatment of the underlying cause. (wellspect.us)
  • or urothelium) - consists of two to three cell layers in the upper ureter with up to ten cell layers near the bladder. (histologyguide.com)
  • loosely arranged smooth muscle in two layers (inner longitudinal and outer circular) in the upper ureter or three layers (inner longitudinal, middle circular and outer longitudinal) near the bladder. (histologyguide.com)
  • RESULTS AND LIMITATIONS: Successful reprogramming of prostate tissue into Pro-iPSCs and bladder and ureter into UT-iPSCs was demonstrated by characteristic ESC morphology, marker expression, and functional pluripotency in generating all three germ-layer lineages. (northumbria.ac.uk)
  • The person has involuntary bladder contractions and feels the need to urinate even when there is little or no urine in the bladder. (msdmanuals.com)
  • Some people with spastic neurogenic bladder also need to urinate frequently, often with an urgent need, and need to get up during the night to urinate. (msdmanuals.com)
  • When the bladder contains about 250 mL (½ pint or 8 ounces) of urine, it sends signals to the brain that you need to urinate soon. (karger.com)
  • You may not empty your bladder completely and may find that you need to urinate more often. (karger.com)
  • CT elegantly demonstrates the urinary bladder mass along the right wall of the bladder with heterogeneous post-contrast enhancement. (radiopaedia.org)
  • The wall of the bladder is made of muscle that stretches like a balloon as it fills with urine. (karger.com)
  • The symptoms of a pelvic organ prolapse (it may even be the rectum or urinary bladder that may prolapse) are a feeling of pressure on the pelvis or actual organs protruding through the vagina or urinary symptoms. (womenhealthzone.com)
  • Self-catheterizing with LoFric helps you make sure the bladder is completely drained, preventing an over-full bladder and the leakage and health problems it can cause. (wellspect.us)
  • In fact, 1 in 3 of us experience Light Bladder Leakage (LBL). (poise.com)
  • It stands for Light Bladder Leakage, and it affects millions of women. (poise.com)
  • The most common symptoms of inverted papillomas, leading to their discovery, are bladder outlet obstruction, hematuria, dysuria, and irritative voiding, with approximately 25% of cases presenting with more than one symptom. (medscape.com)
  • Darifenacin extended-release tablets should be administered with caution to patients with clinically significant bladder outflow obstruction because of the risk of urinary retention. (nih.gov)
  • Over time, the sensation to void is reduced and the muscles of the bladder wall become injured leading to more relaxation and worsening of symptoms. (adventisthealth.org)
  • Urinary Tract Symptoms arise for many women after they have sex or early in marriage. (drfrancescott.com)
  • Our extensive experience at New York Urology Specialists and research studies [ 1 ] both show that transcutaneous posterior tibial nerve stimulation (PTNS) and extended-release oxybutynin (Ditropan XL) are both effective treatments for overactive bladder symptoms. (newyorkurologyspecialists.com)
  • Symptoms can be confusing, because while you may be able to urinate, you may have trouble starting a stream or emptying your bladder completely. (wellspect.us)
  • Involuntary bladder contractions can occur when someone changes position (e.g. bends over), causing overactive bladder symptoms. (karger.com)
  • Your bladder holds less urine than when you were younger, so you may urinate more frequently. (karger.com)
  • Bladder sensation changes with age, which delays the desire to urinate and decreases the 'warning' time (the time between the first urge to urinate and actually urinating). (karger.com)
  • Combined with the delayed desire to urinate, this often results in urinary urgency and frequency. (karger.com)
  • N-Acetyltransferase phenotypes were measured in 228 patients with tumours of the urinary bladder and 100 non-cancer controls. (nih.gov)
  • Histological typing of urinary bladder tumours / F. K. Mostofi, in collaboration with L. H. Sobin, H. Torloni and pathologists in fourteen countries. (who.int)
  • IARC Monographs, volume 73: some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances - summary of data reported and evaluation. (bvsalud.org)
  • Usage information: Energy dependence of urinary bicarbonate secretion in turtle bladder. (jci.org)
  • Energy dependence of urinary bicarbonate secretion in turtle bladder. (jci.org)
  • Carbonic anhydrase function and the epithelial organization of H+ secretion in turtle urinary bladder. (wikidata.org)
  • The involuntary loss of urine that occurs when pressure is suddenly placed on your bladder. (poise.com)
  • Bladder tissue was paraffin embedded, sectioned, mounted, and histologically stained using an Alcian Blue Periodic Acid Schiff staining procedure. (etsu.edu)
  • The bladder tissue from the three treatment groups is being qualitatively analyzed for mucin thickness and types of mucins produced. (etsu.edu)
  • BACKGROUND: Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required. (northumbria.ac.uk)
  • These cells, termed induced pluripotent stem cells (iPSCs), could theoretically generate adult prostate and bladder tissue, providing an alternative strategy to study differentiation. (northumbria.ac.uk)
  • OBJECTIVE: To generate human iPSCs derived from normal, ageing, human prostate (Pro-iPSC), and urinary tract (UT-iPSC) tissue and to assess their capacity for lineage-directed differentiation. (northumbria.ac.uk)
  • Regeneration of bladder cells also provides an exceptional opportunity for translational tissue engineering. (northumbria.ac.uk)
  • Uses include diagnosis and delivery of radiofrequency needle probes, Bugbee electrodes, laser fiberoptics, and needles for injecting anesthetics and ablative, tissue augmenting, bulking, and therapeutic agents into the bladder, prostate, and lower urinary tract. (urologytimes.com)
  • Patients with a variety of abnormalities of the urinary tract had a transplantation success rate comparable to that of azotemic patients with normal urinary systems. (nih.gov)
  • Retention of Schistosoma haematobium eggs and formation of granulomas in the urinary tract can lead not only to hematuria but also to dysuria, bladder polyps and ulcers, and even obstructive uropathies. (medscape.com)
  • Bladder cancer (BC) is the sixth most common malignancy in men and 17th in women. (tu-dortmund.de)
  • It is the most common malignancy of the urinary system. (who.int)
  • Urinary bladder cancer is a common malignancy in industrialized countries. (elsevier.com)
  • Usually, doctors measure the amount of urine remaining in the bladder after the person urinates (postvoid residual volume) by inserting a catheter into the bladder or using ultrasonography. (msdmanuals.com)
  • introduction of a catheter into the bladder to remove fluid to obtain a sterile specimen of urine for testing. (freezingblue.com)
  • A large loss of urine is often experienced as the muscles of the bladder wall start to spasm or contract. (adventisthealth.org)
  • Our model, constrained heavily by physiological data, provides a powerful tool to investigate the ionic mechanisms underlying the genesis of DSM electrical activity, which can further shed light on certain aspects of urinary bladder function and dysfunction. (yale.edu)
  • Though surgery is seen to be the only solution for prolapse, this can be cause for other complications such as bowel and bladder dysfunction, chronic pain, sexual loss, and emotional devastation. (womenhealthzone.com)
  • Neurogenic bladder is defined as urinary bladder malfunction due to neurologic dysfunction. (bmj.com)
  • We present an uncommon case of mucinous adenocarcinoma of the bladder (MAB) with signet-ring cells extensively infiltrating prostate gland and pelvic/retroperitoneal lymph node stations and not responsive to usual systemic chemotherapy regimens. (hindawi.com)
  • This tumor has overlapping histological characteristics with adenocarcinomas arising from other primary sites such as colon, prostate, and gynecological tract, whereby immunohistochemistry is essential to determine the primary origin from the bladder. (hindawi.com)
  • Ultrasonography (US) of abdomen and pelvis showed the presence of considerable chronic urinary retention with a postvoid residual (PVR) equal to almost 200 cc and confirmed the presence of an enlarged prostate with neither hypoechoic nor suspicious lesions. (hindawi.com)
  • OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The potential for differentiation into prostate and bladder lineages was compared with classical skin-derived iPSCs. (northumbria.ac.uk)
  • CONCLUSIONS: IPSCs provide an exciting new model to characterise mechanisms regulating prostate and bladder differentiation and to develop novel approaches to disease modelling. (northumbria.ac.uk)
  • This is related to falling of pelvic organs like the bladder and uterus. (adventisthealth.org)
  • Unilateral removal of the pelvic ganglion affected the bladder-half on the denervated side more profoundly than that on the non-denervated side. (lu.se)
  • article{a1ddb064-ad61-4752-bf53-d87ca4ce9999, abstract = {{Unilateral removal of the pelvic ganglion affected the bladder-half on the denervated side more profoundly than that on the non-denervated side. (lu.se)
  • The bladder and womb (uterus) lie on top of the pelvic floor. (karger.com)
  • Addition of HCO3- to the serosal side (S) of the isolated turtle bladder results in a HCO3- flow from S to the mucosal side (M) which markedly reduces the net rate of acid secretion. (jci.org)
  • This eventually allows residual bacteria to overwhelm local bladder mucosal defenses. (medscape.com)
  • Background: Urinary bladder cancer is the fourth most common cancer in Jordan. (who.int)
  • No research on survival from bladder cancer at the national level has been conducted before. (who.int)
  • Bladder cancer is a significant cause of cancer morbidity and mortality, accounting for an estimated 68 810 new cases and 14 100 cancer deaths in the United States in 2008. (nature.com)
  • Historically, the term 'superficial bladder cancer' has been used to describe tumors that have not invaded into muscularis propria. (nature.com)
  • Transcript levels of lncRNAs in urinary exosomes are potential diagnostic biomarkers in bladder cancer. (tu-dortmund.de)
  • Urinary bladder cancer is the fourth most common cancer in Jordan. (who.int)
  • This study aimed to estimate the probability of survival in patients with bladder cancer in Jordan and identify factors associated with survival. (who.int)
  • All cases of urinary bladder cancer in Jordanians registered during 2005-2014 were included in the study (n = 2139). (who.int)
  • The overall 1-, 3-, 5- and 10-year survival probabilities for urinary bladder cancer were 85%, 73%, 69% and 59%, respectively (standard error = 0.01 for each). (who.int)
  • The survival of patients with bladder cancer in Jordan is comparable to that reported from developed countries. (who.int)
  • Urinary bladder cancer is a form of cancer primarily arising in the tissues of the urinary bladder. (who.int)
  • There are three main types of bladder cancer: transitional cell carcinoma, squamous cell carcinoma and adenocarcinoma (1). (who.int)
  • Urothelial (transitional cell) carcinoma is the most common histological type of bladder cancer, accounting for almost 90% of all cases. (who.int)
  • Squamous cell carcinoma accounts for about 4% of cases of bladder cancer, adenocarcinoma for about 2% and all other types for about 4% of cases (2). (who.int)
  • According to the global cancer statistics, bladder cancer is the 10th most common cancer in the world, with an estimated 549 393 new cases and 7.2/100 100 population crude death rate in 2018 (3,4). (who.int)
  • About 60% of all bladder cancer cases and 50% of bladder cancer deaths occur in the less developed regions of the world (5). (who.int)
  • Greece is reported to have the highest rates of bladder cancer among men with an age standardized rate of 40.4 cases per 100 000, while Lebanon has the highest rate among women with 9.4 cases per 100 000 in 2018 (6). (who.int)
  • According to the National Cancer Institute in the United States of America (USA), urinary bladder cancer is the sixth most common cancer in the country, accounting for 4.7% of new cases of cancer and 2.8% of all cancer deaths in 2017 (7). (who.int)
  • In Sweden, the 5-year relative survival rate for 31 266 patients (74% men, 26% women) with urinary bladder cancer diagnosed from 1997 to 2011 was 72% (10). (who.int)
  • More than 90% of bladder cancer originates in the transitional cells. (elsevier.com)
  • Bladder transitional cancer prognosis is, according to the most recent definition related to the level of tumor infiltration, characterized by two main phenotypes, Non Muscle Invasive Bladder Transitional Cancer (NMIBC) and Muscle Invasive Bladder Transitional Cancer (MIBC). (elsevier.com)
  • It has recently been reported that the chromosomal region 12q13-15, containing crucial cancer genes such as MDM2, CDK4, GLI and an entire cluster of HOX genes, is amplified in bladder cancer. (elsevier.com)
  • In this study we have been investigated, by immunohistochemisty and quantitative Real Time PCR, the HOX B13 expression in bladder cancer evolution and progression, evaluating its ability to discriminate between NMIBC and MBCI phenotypes. (elsevier.com)
  • The de-regulation and delocalization of HOX B13 in urinary bladder cancer supports again the important role of HOX genes in tumor evolution and represents a starting point to establish an integrated analysis, in which HOX genes represent important prognostic and predictive markers for bladder cancer. (elsevier.com)
  • The Potential Role of Telomerase Reverse Transcriptase Promoter Mutations asNon-Invasive Urinary Biomarkers in Bladder Cancer Detection: Is the New Droplet Digital Assay (ddPCR) Reliable to be Clinically Used? (imedpub.com)
  • Bladder cancer is the second most common cancer of the genitourinary system. (imedpub.com)
  • There is no accepted screening test for bladder cancer. (imedpub.com)
  • Recently, Telomerase Reverse Transcriptase gene mutations have been hailed as the most common bladder cancer mutations. (imedpub.com)
  • In this cross-sectional study, patients with bladder cancer and healthy controls were evaluated. (imedpub.com)
  • 31 primary or recurrent bladder cancer cases and 50 controls were evaluated. (imedpub.com)
  • TERT promoter mutations could be a way for detection of bladder cancer. (imedpub.com)
  • Data on 482 stage A-0 - D2 bladder cancer patients referred between 1975-86 were analyzed. (bgu.ac.il)
  • Quantitative exposure to metalworking fluids and bladder cancer incidence in a cohort of autoworkers. (cdc.gov)
  • Occupations with mineral oil exposure have been associated with bladder cancer in population-based case-control studies. (cdc.gov)
  • The authors report results from the first cohort study to examine bladder cancer incidence in relation to quantitative exposures to metalworking fluids (MWFs), based on 21,999 male Michigan automotive workers, followed from 1985 through 2004. (cdc.gov)
  • Increased bladder cancer risk was associated with straight MWFs but not with any other exposure. (cdc.gov)
  • The urinary form of schistosomiasis is also associated with an increased risk for bladder cancer in adults. (who.int)
  • Dietary fats and their sources in association with the risk of bladder cancer: A pooled analysis of 11 prospective cohort studies. (who.int)
  • Molecular Diagnostic and Prognostication Assays for the Subtyping of Urinary Bladder Cancer Are on the Way to Illuminating Our Vision. (who.int)
  • The inability to empty the bladder completely can have many causes, which are generally divided into acute urinary retention and chronic urinary retention. (wellspect.us)
  • Besides a clear and sudden inability to void the bladder, people with acute urinary retention usually experience a distended abdomen. (wellspect.us)
  • Complications of untreated urinary retention can include bladder damage and chronic kidney failure. (wellspect.us)
  • Chronic urinary retention is, like acute retention, commonly caused by a separate condition that requires treatment. (wellspect.us)
  • This is serious, as the treatment for overactivity is basically to "calm the bladder down" with pharmaceuticals - which, of course, increases the level of retention. (wellspect.us)
  • But when you are experiencing retention, it may prevent you from emptying your bladder completely. (wellspect.us)
  • First, I must say that female urinary retention is a quite rare condition if we're comparing to a male gender. (thaiuroincambodia.com)
  • Urinary retention is a common complaint at my Urology office. (thaiuroincambodia.com)
  • Urinary retention being defined as the acute retention of urine, affects millions of people all over the world with the prevalence increasing in elderly. (thaiuroincambodia.com)
  • Desai P, Transitional cell carcinoma - urinary bladder. (radiopaedia.org)
  • To determine the possible effects of microgravity on mucin production in the urinary bladder, we examined the transitional epithelium of the urinary bladder from female mice that were flown on the space shuttle Endeavour for 12 days in August, 2007. (etsu.edu)
  • Pyelonephritis is almost always the result of bacterial migration from the bladder to the renal parenchyma that is enhanced by vesicourethral reflux. (medscape.com)
  • Most people do not feel an urge to pass urine until there is about 150-200 mL (about a quarter of a pint) in the bladder. (karger.com)
  • Most UTIs develop when bacteria enter the urinary tract from outside the body. (medicalnewstoday.com)
  • It is now recognized that 'superficial' bladder carcinomas are a heterogenous group of tumors with diverse biological and clinical manifestations. (nature.com)
  • This review will discuss recent progress and controversial issues on the staging and substaging of bladder carcinomas. (nature.com)
  • Bladder contractions are typically poorly coordinated with the muscle that closes the opening of the bladder (urinary sphincter). (msdmanuals.com)
  • A ring of muscle, called the internal sphincter, at the neck or base of the bladder acts like a tap or valve, keeping the urine in. (karger.com)
  • It happens because control over the urinary sphincter is either lost or weakened. (wearable-technologies.com)
  • We thus assessed the published transcriptome of urinary bladder urothelial carcinoma (UBUC) and identified insulin-like growth factor-binding protein-5 (IGFBP-5) as the most significantly upregulated gene associated with the regulation of cell growth. (elsevier.com)
  • Neurogenic bladder is lack of bladder control because of a nerve problem such as a stroke, spinal cord injury, or tumor. (msdmanuals.com)
  • The majority (70%) of inverted papillomas occur in the bladder, most often in the trigone, followed by the bladder neck, bladder dome, posterior wall, and lateral wall. (medscape.com)
  • Because magnesium ammonium phosphate is acid soluble, stone formation does not tend to occur with a urinary pH lower than 7.19. (medscape.com)
  • They may occur anywhere from the base of the brain to the urinary bladder. (medscape.com)
  • The trigone, the bladder neck, and both ureteral orifices are identified. (medscape.com)
  • red sand in urine, on child's diaper, child cries before urinating, pain in back relieved by urinating, renal colic, stitches simultaneously in the anus and neck of the bladder, scanty, dark red, clear with uric acid deposits. (hpathy.com)
  • Virtual cystoscopy: the evaluation of bladder lesions with computed tomographic virtual cystoscopy. (medscape.com)
  • Flat intraurothelial lesions of the urinary bladder-do hyperplasia, dysplasia, and atypia of unknown significance need to exist as diagnostic entities? (nature.com)
  • In conclusion, our device contributes to ultrasound training by providing a realistic ultrasound image, improving image understanding and skill development and allowing reliable bladder volume estimation. (elsevier.com)
  • Ultrasound 1: Urinary bladder, longitudinal. (kinderradiologie-online.de)
  • Ultrasound 2: Urinary bladder, horizontal, Photopic-Mode. (kinderradiologie-online.de)
  • The 2004 Surgeon General report found convincing evidence for a direct causal relationship between tobacco use and the following cancers: lung and bronchial, laryngeal, oral cavity and pharyngeal, esophageal, stomach, pancreatic, kidney and renal pelvis, urinary bladder, and cervical cancers and acute myelogenous leukemia (AML). (cdc.gov)
  • People with spastic neurogenic bladder may have damage to other nerves that causes weakness, muscle spasms, and/or loss of sensation in the legs. (msdmanuals.com)
  • Oxybutynin (brand name Ditropan) is an anticholinergic drug that relieves urinary difficulties by decreasing muscle spasms in the bladder. (newyorkurologyspecialists.com)
  • Magnesium reduces bladder muscle spasms and helps to maintain proper muscle and nerve function. (howtowhere.com)
  • Being hydrated also dilutes the urine and speeds its journey through the system, making it harder for bacteria to reach and infect the cells that line the urinary organs. (medicalnewstoday.com)
  • Schistosomiasis also can be associated with salmonellosis and squamous cell malignancies of the bladder. (medscape.com)
  • Home Varice simptome uretrale Las várices son una enfermedad común y muy frecuente sin embargo y por fortuna schistosomiasis urinary bladder complicaciones no se ven muy a menudo pero cuando aparecen pueden ser alarmantes, peligrosas y en algunos casos comprometer seriamente el bienestar del paciente e incluso su vida. (evenimente-corporate.ro)
  • Am niste vinisoare rosii pe picioare, un inceput de varice, Schistosomiasis urinary bladder adevarat ca daca am deja semne de varice de la 29 de ani, sa fie sanse mari sa am trombofilie. (evenimente-corporate.ro)
  • Urologia este specialitatea care se ocupa de depistarea, tratarea si recuperarea chirurgicala a bolnavilor cu suferinte ale aparatului urinar schistosomiasis urinary bladder barbat si femeie rinichi, uretere, vezica urinara, uretraprecum si ale aparatului genital masculin testicul, epididim, penis, prostata, vezicule seminale, ducte deferente. (evenimente-corporate.ro)
  • Bleeding schistosomiasis urinary bladder are a life- threatening complication of this increase in blood pressure portal hypertension. (evenimente-corporate.ro)
  • A patient with severe schistosomiasis urinary bladder rectal bleeding from anorectal varices due to portal hypertension because of schistosomiasis urinary bladder C virus related liver cirrhosis is presented. (evenimente-corporate.ro)