Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
A PEPTIC ULCER located in the DUODENUM.
Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.
A skin ulcer is an open sore or break in the skin that fails to heal on its own within a reasonable period of time.
Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.
Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.
A lesion in the skin and subcutaneous tissues due to infections by MYCOBACTERIUM ULCERANS. It was first reported in Uganda, Africa.
Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
A slow-growing mycobacterium that infects the skin and subcutaneous tissues, giving rise to indolent BURULI ULCER.
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
Material used for wrapping or binding any part of the body.
Vagal denervation of that part of the STOMACH lined with acid-secreting mucosa (GASTRIC MUCOSA) containing the GASTRIC PARIETAL CELLS. Since the procedure leaves the vagal branches to the antrum and PYLORUS intact, it circumvents gastric drainage required with truncal vagotomy techniques.
Hydrochloric acid present in GASTRIC JUICE.
The liquid secretion of the stomach mucosa consisting of hydrochloric acid (GASTRIC ACID); PEPSINOGENS; INTRINSIC FACTOR; GASTRIN; MUCUS; and the bicarbonate ion (BICARBONATES). (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p651)
A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.
The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.
Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
Endoscopic examination, therapy or surgery of the interior of the stomach.
Endoscopic examination, therapy or surgery of the luminal surface of the duodenum.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
The return of a sign, symptom, or disease after a remission.
A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters.
The region of the STOMACH at the junction with the DUODENUM. It is marked by the thickening of circular muscle layers forming the pyloric sphincter to control the opening and closure of the lumen.
Impaired digestion, especially after eating.
Control of bleeding performed through the channel of the endoscope. Techniques include use of lasers, heater probes, bipolar electrocoagulation, and local injection. Endoscopic hemostasis is commonly used to treat bleeding esophageal and gastrointestinal varices and ulcers.
Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
Substances that counteract or neutralize acidity of the GASTROINTESTINAL TRACT.
Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
Gastrointestinal symptoms resulting from an absent or nonfunctioning pylorus.
A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
Pathological processes in the ESOPHAGUS.
Evaluation of the nature and extent of nursing problems presented by a patient for the purpose of patient care planning.
Equipment on which one may lie and sleep, especially as used to care for the hospital patient.
A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
A variety of surgical reconstructive procedures devised to restore gastrointestinal continuity, The two major classes of reconstruction are the Billroth I (gastroduodenostomy) and Billroth II (gastrojejunostomy) procedures.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.
Material, usually gauze or absorbent cotton, used to cover and protect wounds, to seal them from contact with air or bacteria. (From Dorland, 27th ed)
Gastric analysis for determination of free acid or total acid.
A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
A species of HAEMOPHILUS that appears to be the pathogen or causative agent of the sexually transmitted disease, CHANCROID.
Vomiting of blood that is either fresh bright red, or older "coffee-ground" in character. It generally indicates bleeding of the UPPER GASTROINTESTINAL TRACT.
A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.
An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Therapy with two or more separate preparations given for a combined effect.
Inflammation of the DUODENUM section of the small intestine (INTESTINE, SMALL). Erosive duodenitis may cause bleeding in the UPPER GI TRACT and PEPTIC ULCER.
The black, tarry, foul-smelling FECES that contain degraded blood.
Infections with nontuberculous mycobacteria (atypical mycobacteria): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae.
Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.
The removal of a limb or other appendage or outgrowth of the body. (Dorland, 28th ed)
Strips of elastic material used to apply pressure to body parts to control EDEMA and aid circulation.
Elements of limited time intervals, contributing to particular results or situations.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A genus of leguminous herbs or shrubs whose roots yield GLYCYRRHETINIC ACID and its derivative, CARBENOXOLONE.
Substances that reduce the growth or reproduction of BACTERIA.
Research carried out by nurses that uses interviews, data collection, observation, surveys, etc., to evaluate nursing, health, clinical, and nursing education programs and curricula, and which also demonstrates the value of such evaluation.
Tumors or cancer of the STOMACH.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).
Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.
Death and putrefaction of tissue usually due to a loss of blood supply.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Anatomical and functional disorders affecting the foot.
A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.
Tongue diseases refer to medical conditions that affect the tongue, including infections, inflammation, and structural abnormalities.
Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Skin diseases caused by bacteria.
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.
A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
A republic in western Africa, south of NIGER and between TOGO and NIGERIA. Its capital is Porto-Novo. It was formerly called Dahomey. In the 17th century it was a kingdom in the southern area of Africa. Coastal footholds were established by the French who deposed the ruler by 1892. It was made a French colony in 1894 and gained independence in 1960. Benin comes from the name of the indigenous inhabitants, the Bini, now more closely linked with southern Nigeria (Benin City, a town there). Bini may be related to the Arabic bani, sons. (From Webster's New Geographical Dictionary, 1988, p136, 310 & Room, Brewer's Dictionary of Names, 1992, p60)
An act of employing sorcery (the use of power gained from the assistance or control of spirits), especially with malevolent intent, and the exercise of supernatural powers and alleged intercourse with the devil or a familiar. (From Webster, 3d ed)
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
An enzyme that catalyzes the conversion of urea and water to carbon dioxide and ammonia. EC 3.5.1.5.
A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.
Infections in the inner or external eye caused by microorganisms belonging to several families of bacteria. Some of the more common genera found are Haemophilus, Neisseria, Staphylococcus, Streptococcus, and Chlamydia.
The therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). It is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (From Segen, Dictionary of Modern Medicine, 1992). The list of treatment modalities includes stroke.
Pathological development in the ILEUM including the ILEOCECAL VALVE.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.
Research carried out by nurses in the clinical setting and designed to provide information that will help improve patient care. Other professional staff may also participate in the research.
Invasion of the site of trauma by pathogenic microorganisms.
A genus of bacteria causing GRANULOMA INGUINALE and other granulomatous lesions.
Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
The segment of GASTROINTESTINAL TRACT that includes the ESOPHAGUS; the STOMACH; and the DUODENUM.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
A republic in western Africa, south of BURKINA FASO and west of TOGO. Its capital is Accra.
Pathological processes of the VULVA.
The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.
The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.
The inferior part of the lower extremity between the KNEE and the ANKLE.
A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
A non-atherosclerotic, inflammatory thrombotic disease that commonly involves small and medium-sized arteries or veins in the extremities. It is characterized by occlusive THROMBOSIS and FIBROSIS in the vascular wall leading to digital and limb ISCHEMIA and ulcerations. Thromboangiitis obliterans is highly associated with tobacco smoking.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Osteomyelitis is an infection of the bone and bone marrow, typically caused by bacteria or fungi.
Complexes of iodine and non-ionic SURFACE-ACTIVE AGENTS acting as carrier and solubilizing agent for the iodine in water. Iodophors usually enhance bactericidal activity of iodine, reduce vapor pressure and odor, minimize staining, and allow wide dilution with water. (From Merck Index, 11th ed)
The placing of a body or a part thereof into a liquid.
An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Pathological processes involving the PENIS or its component tissues.
Use of plants or herbs to treat diseases or to alleviate pain.
Substances elaborated by bacteria that have antigenic activity.
Tuberculosis of the mouth, tongue, and salivary glands.
Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.
Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The evacuation of food from the stomach into the duodenum.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Facilities which provide nursing supervision and limited medical care to persons who do not require hospitalization.
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
Any one of five terminal digits of the vertebrate FOOT.
Any tests done on exhaled air.
The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A constitutively-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes.
GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.
The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
Abnormal passage communicating with the STOMACH.
Human or animal tissue used as temporary wound coverings.
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
L-Tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide. The C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.
Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
Inorganic compounds that contain silver as an integral part of the molecule.
A naturally occurring dipeptide neuropeptide found in muscles.
A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
Infection of the genitals (GENITALIA) with HERPES SIMPLEX VIRUS in either the males or the females.
Pathological processes involving any part of the AORTA.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Pathological development in the JEJUNUM region of the SMALL INTESTINE.
An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).
An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
The hospital department which is responsible for the organization and administration of nursing activities.
The hindering of output from the STOMACH into the SMALL INTESTINE. This obstruction may be of mechanical or functional origin such as EDEMA from PEPTIC ULCER; NEOPLASMS; FOREIGN BODIES; or AGING.
A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of nursing care.
The insertion of a tube into the stomach, intestines, or other portion of the gastrointestinal tract to allow for the passage of food products, etc.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Sequelae of gastrectomy from the second week after operation on. Include recurrent or anastomotic ulcer, postprandial syndromes (DUMPING SYNDROME and late postprandial hypoglycemia), disordered bowel action, and nutritional deficiencies.
Mucins that are found on the surface of the gastric epithelium. They play a role in protecting the epithelial layer from mechanical and chemical damage.
Proteins found in any species of bacterium.
A puncture or hole through the CORNEAL STROMA resulting from various diseases or trauma.
The S-isomer of omeprazole.
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.
A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.
Inhaling and exhaling the smoke of burning TOBACCO.
The giving of drugs, chemicals, or other substances by mouth.
Stomatitis caused by Herpesvirus hominis. It usually occurs as acute herpetic stomatitis (or gingivostomatitis), an oral manifestation of primary herpes simplex seen primarily in children and adolescents.
Anogenital ulcers caused by Calymmatobacterium granulomatis as distinguished from lymphogranuloma inguinale (see LYMPHOGRANULOMA VENEREUM) caused by CHLAMYDIA TRACHOMATIS. Diagnosis is made by demonstration of typical intracellular Donovan bodies in crushed-tissue smears.
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Opening or penetration through the wall of the INTESTINES.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
Either of two fleshy protuberances at the lower posterior section of the trunk or HIP in humans and primate on which a person or animal sits, consisting of gluteal MUSCLES and fat.
Drugs that act on blood and blood-forming organs and those that affect the hemostatic system.

Risk of human immunodeficiency virus infection and genital ulcer disease among persons attending a sexually transmitted disease clinic in Italy. (1/631)

To assess the relative importance of ulcerative and non-ulcerative sexually transmitted disease in the transmission of HIV, a seroprevalence study was conducted on 2210 patients at the sexually transmitted diseases (STD) clinic of the S. Maria e S. Gallicano Hospital in Rome, between 1989 and 1994. Among male patients, by univariate analysis, strong predictors of HIV infection were homosexuality, sexual exposure to a HIV-positive partner, hepatitis B virus infection, and positive syphilis serology. An increased risk was estimated for patients with past genital herpes (odds ratio (OR) 3.86, 95% confidence intervals (CI) 0.40-18.2), and primary syphilis (OR 5.79, 95% CI 0.59-28.6). By multivariate analysis, a positive association was found with homosexuality (OR 6.9, 95% CI 2.9-16.5), and positive syphilis serology (OR 3.5, 95% CI 1.3-9.2). An adjusted OR of 2.41 was calculated for current and/or past genital herpes. These results, although not conclusive, suggest a role of ulcerative diseases as risk factors for prevalent HIV infection, and indicate that positive syphilis serology is an unbiased criterion for identifying individuals at increased risk of HIV infection.  (+info)

The pathophysiology of disseminated Mycobacterium avium complex disease in AIDS. (2/631)

Mycobacterium avium complex (MAC) organisms cause disseminated disease in patients with AIDS. The organisms penetrate the gastrointestinal mucosa by unknown mechanisms and are phagocytosed by macrophages in the lamina propria. These cells cannot kill the organisms, and MAC spreads through the submucosal tissue. Lymphatic drainage transports mycobacteria to abdominal lymph nodes, from which the organisms enter the bloodstream. Hematogenous spread can occur to many sites, but spleen, bone marrow, and liver are the most common. Tissue destruction is rare, and most signs and symptoms of MAC disease are due to elaboration of cytokines. MAC is rarely the direct cause of death but increases the risk for superinfection; death may result from malnutrition or other infections.  (+info)

Penetrating atherosclerotic ulcer at the proximal aorta complicated with cardiac tamponade and aortic valve regurgitation. (3/631)

A 56-year-old man had a penetrating atherosclerotic ulcer originating in the proximal ascending aorta, which is an unusual case of penetrating aortic ulcer complicated with the aortic valve regurgitation and cardiac tamponade. This hemodynamically unstable patient was successfully treated by conservative management to control his blood pressure and was also monitored closely with follow-up imaging studies.  (+info)

Small intestinal ulceration secondary to carcinoid tumour arising in a Meckel's diverticulum. (4/631)

A solitary small intestinal ulcer associated with a carcinoid tumour in a nearby Meckel's diverticulum was found in a 77 year old man presenting with massive rectal bleeding. Angiography and a radioisotope study localised the bleeding to the ileum. At operation, the Meckel's diverticulum was identified, with bleeding from an ulcer just distal to it. Pathological examination revealed a small carcinoid tumour confined to the Meckel's diverticulum. Close to the opening of the diverticulum, within the ileum, a well demarcated ulcer was present. Histology showed a non-specific ulcer which eroded a large blood vessel. This is the first documented occurrence of solitary small intestinal ulceration in association with a carcinoid tumour. Carcinoid tumour should be added to the list of possible causes of small intestinal ulceration. The ulceration may be secondary to release of cytokines by the tumour.  (+info)

Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. (5/631)

A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV). Twenty-four HIV-infected patients with biopsy-confirmed aphthous ulceration of the esophagus were randomly assigned to receive either oral thalidomide, 200 mg/day, or oral placebo daily for 4 weeks. Eight (73%) of 11 patients randomized to receive thalidomide had complete healing of aphthous ulcers at the 4-week endoscopic evaluation, compared with 3 (23%) of 13 placebo-randomized patients (odds ratio, 13.82; 95% confidence interval, 1.16-823.75; P=.033). Odynophagia and impaired eating ability caused by esophageal aphthae were improved markedly by thalidomide treatment. Adverse events among patients receiving thalidomide included somnolence (4 patients), rash (2 patients), and peripheral sensory neuropathy (3 patients). Thalidomide is effective in healing aphthous ulceration of the esophagus in patients infected with HIV.  (+info)

Fas receptor up-regulation and membrane localization concurrent with apoptosis in idiopathic esophageal ulceration: toward a better understanding of esophageal injury in AIDS. (6/631)

Activation of the Fas-mediated apoptotic pathway in the etiology of idiopathic esophageal ulcerations (IEUs) was investigated. Constitutive expression of Fas ligand (Fas L) was found in the basal layer of the normal esophageal mucosa and in IEUs and cytomegalovirus ulcerations. In addition to an altered cytokine environment, there was significant up-regulation of Fas antigen mRNA and membrane localization of the receptor in IEU specimens. Concomitant increase in the basic components of Fas machinery, together with elevated mucosal apoptosis, strongly suggests the potential role of the Fas signaling pathway in the onset of tissue destruction associated with IEUs.  (+info)

Leishmania amazonensis infection in nude mice. (7/631)

Leishmania amazonensis is an intracellular protozoan parasite of macrophages. Cutaneous leishmaniasis in an immunocompetent host begins as papules or nodules followed by ulceration at the site of promastigote inoculation. In this study, the pathological changes of cutaneous leishmaniasis lesions in T cell deficient nude mice were examined. When infected with L. amazonensis promastigotes, nude mice developed non-ulcerative cutaneous nodules. By histological examination of cutaneous lesions, massive accumulation of vacuolated histiocytes containing amastigotes was observed in all the nude mice. Although infiltration of mononuclear and polymorphonuclear cells was seen in the lesions of immunocompetent mice, few such cells were observed in the lesions of nude mice. These results indicate the importance of T cells on the ulcer formation in cutaneous leishmaniasis.  (+info)

Accuracy and economics of Helicobacter pylori diagnosis. (8/631)

Many diagnostic tests are available to establish Helicobacter pylori infection status. Most of the tests are accurate though none works perfectly, and no gold standard for diagnosis exists. Newly developed serum immunoassay kits can substitute for laboratory-based enzyme-linked immunosorbent assays, but whole blood immunoassays do not yet demonstrate adequate performance characteristics. Serologic diagnosis of H. pylori remains the most cost-effective option and should be utilized to establish initial infection in the majority of cases. If rapid urease testing is performed at endoscopy, negative results can be confirmed with a subsequent serologic test in those patients with a high probability of infection. Obtaining additional gastric tissue at endoscopy to evaluate for bacterial infection is reasonable if specimens are being taken for a mucosal defect. Confirmation of bacterial eradication cannot be justified for all post-treatment patients at present due to the expense. It is important to test for cure in those patients with complicated ulcer disease and those with recurrent symptoms after therapy.  (+info)

A stomach ulcer is a sore or open wound in the lining of the stomach or duodenum (the first part of the small intestine). It is caused by a combination of factors, including the bacteria Helicobacter pylori, excessive production of stomach acid, and the use of certain medications, such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). Stomach ulcers can cause a range of symptoms, including abdominal pain, bloating, nausea, vomiting, and loss of appetite. In some cases, ulcers can lead to more serious complications, such as bleeding, perforation, and the formation of a stomach abscess. Treatment for stomach ulcers typically involves a combination of medications, such as antibiotics to kill H. pylori bacteria, acid-suppressing drugs to reduce stomach acid production, and pain relievers. In some cases, surgery may be necessary to repair a perforated ulcer or remove a large abscess.

A duodenal ulcer is a sore or break in the lining of the duodenum, which is the first part of the small intestine. It is a common condition that affects millions of people worldwide. The most common symptoms of a duodenal ulcer include abdominal pain, bloating, nausea, and loss of appetite. The pain is usually located in the upper abdomen, just below the ribs, and may be relieved by eating or taking antacids. Duodenal ulcers are usually caused by a combination of factors, including the bacteria Helicobacter pylori, long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), and excessive alcohol consumption. Treatment typically involves antibiotics to kill H. pylori, as well as medications to reduce stomach acid production and pain relief. In severe cases, surgery may be necessary.

A peptic ulcer is a sore that forms in the lining of the stomach or duodenum, which is the first part of the small intestine. It is caused by a combination of factors, including the production of excess stomach acid and the presence of the bacterium Helicobacter pylori (H. pylori) in the stomach. Peptic ulcers can cause a range of symptoms, including abdominal pain, bloating, nausea, and vomiting. They can also lead to complications such as bleeding, perforation, and the formation of. Treatment typically involves the use of medications to reduce stomach acid production and antibiotics toH. pylori, as well as lifestyle changes such as avoiding spicy or acidic foods and not smoking.

A leg ulcer is a wound that forms on the skin of the leg, typically on the lower leg or ankle. It is usually a chronic condition that does not heal on its own and can be caused by a variety of factors, including poor circulation, venous insufficiency, arterial disease, diabetes, and obesity. Leg ulcers can be painful and may lead to infection if not properly treated. Treatment typically involves addressing the underlying cause of the ulcer, as well as cleaning and dressing the wound to promote healing. In some cases, surgery may be necessary to improve blood flow or remove damaged tissue.

A pressure ulcer, also known as a bedsore or decubitus ulcer, is a localized injury to the skin and underlying tissue that occurs when there is prolonged or excessive pressure on a particular area of the body. Pressure ulcers are most commonly seen in people who are bedridden or have limited mobility, as the constant pressure on certain areas of the body can cause the blood flow to be restricted, leading to tissue damage. Pressure ulcers can occur anywhere on the body where there is prolonged pressure, but they are most commonly seen on the back of the head, heels, hips, and tailbone. The severity of a pressure ulcer can range from a red, painful area of skin to a deep, open wound that extends through the underlying tissue. Treatment for pressure ulcers typically involves relieving pressure on the affected area, keeping the wound clean and moist, and providing nutritional support to promote healing. In severe cases, surgery may be necessary to remove damaged tissue or repair underlying structures. Prevention of pressure ulcers is also important, and can involve regular repositioning of the patient, the use of specialized pressure-relieving devices, and maintaining good nutrition and hydration.

A skin ulcer is an open sore or break in the skin that does not heal on its own. It can be caused by a variety of factors, including pressure, injury, infection, poor circulation, and underlying medical conditions such as diabetes or venous insufficiency. Skin ulcers can range in size from small pinprick wounds to large, deep sores that extend down to the underlying tissue. They can be painful and may take a long time to heal, especially if they are not properly treated. Treatment for skin ulcers typically involves cleaning and dressing the wound, managing any underlying medical conditions, and addressing any underlying causes of the ulcer. In some cases, surgery may be necessary to remove damaged tissue or repair damaged blood vessels.

Peptic Ulcer Hemorrhage (PUH) is a medical condition that occurs when a peptic ulcer in the stomach or duodenum (the first part of the small intestine) bleeds. The bleeding can be mild or severe, and it can occur suddenly or gradually over time. PUH is a serious condition that requires prompt medical attention. The bleeding can cause symptoms such as black or tarry stools, (vomiting blood), weakness, dizziness, and fainting. In severe cases, PUH can lead to shock, which is a life-threatening condition. The most common cause of PUH is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or other medications that irritate the stomach lining. Other risk factors include smoking, excessive alcohol consumption, chronic stress, and a history of peptic ulcers. Treatment for PUH typically involves stopping the bleeding and preventing further bleeding. This may involve medications to reduce stomach acid production, endoscopic therapy to stop the bleeding, or surgery to remove the affected part of the stomach or duodenum. In severe cases, hospitalization and intensive care may be necessary.

Peptic Ulcer Perforation (PUP) is a medical emergency that occurs when a peptic ulcer in the stomach or duodenum (the first part of the small intestine) perforates, or breaks through, the wall of the stomach or duodenum. This can cause a leak of digestive juices and contents into the abdominal cavity, leading to a severe infection and potentially life-threatening complications. PUP is a complication of peptic ulcers, which are ulcers that form in the lining of the stomach or duodenum due to chronic inflammation caused by the bacteria Helicobacter pylori or the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen. Other risk factors for PUP include smoking, excessive alcohol consumption, and stress. Symptoms of PUP may include severe abdominal pain, tenderness, nausea, vomiting, and fever. If left untreated, PUP can lead to sepsis, peritonitis (infection of the abdominal lining), and even death. Treatment for PUP typically involves emergency surgery to repair the perforation and remove any infected tissue. Antibiotics may also be prescribed to treat any bacterial infection. After surgery, patients may need to stay in the hospital for several days to recover and receive intravenous fluids and medications to manage pain and prevent infection.

Buruli ulcer is a skin infection caused by the bacterium Mycobacterium ulcerans. It is a type of mycobacterial disease that primarily affects children and young adults in tropical and subtropical regions of Africa, Asia, and the Pacific. The disease is named after the town of Buruli in Ivory Coast, where it was first identified in the 1960s. The initial symptoms of Buruli ulcer are a painless, ulcerative lesion on the skin, which can grow rapidly and become deep and disfiguring. The disease can also spread to nearby lymph nodes and cause systemic symptoms such as fever, fatigue, and weight loss. In severe cases, the infection can lead to permanent disability or even death. Buruli ulcer is typically diagnosed through a combination of clinical examination, skin biopsy, and laboratory testing. Treatment involves a combination of antibiotics and surgery to remove the infected tissue. Prevention efforts include public education about the disease, improved sanitation and hygiene, and the use of protective clothing and insect repellent in high-risk areas.

The diabetic foot is a condition that affects people with diabetes, particularly those with poorly controlled blood sugar levels. It refers to a group of foot-related problems that can occur as a result of diabetes, including infections, ulcers, nerve damage, and circulation problems. The diabetic foot can lead to serious complications, such as amputation, if left untreated. It is important for people with diabetes to take good care of their feet by inspecting them regularly for any signs of injury or infection, keeping them clean and dry, wearing properly fitting shoes, and seeking medical attention promptly if any problems arise.

Helicobacter infections refer to a group of bacterial infections caused by the bacterium Helicobacter pylori (H. pylori). H. pylori is a gram-negative, spiral-shaped bacterium that is commonly found in the stomach and upper part of the small intestine. It is estimated that more than half of the world's population is infected with H. pylori, and the majority of infected individuals do not experience any symptoms. H. pylori infections can lead to a range of health problems, including gastritis (inflammation of the stomach lining), peptic ulcers (sores in the lining of the stomach or duodenum), and stomach cancer. In some cases, H. pylori infections can also cause symptoms such as abdominal pain, bloating, nausea, and vomiting. Diagnosis of H. pylori infections typically involves a combination of tests, including a breath test, stool test, and endoscopy with biopsy. Treatment typically involves a combination of antibiotics and proton pump inhibitors, which can help to eliminate the bacteria and reduce inflammation in the stomach. Prevention of H. pylori infections involves good hygiene practices, such as washing hands regularly and avoiding close contact with infected individuals. Vaccines for H. pylori are currently being developed, but are not yet available for widespread use.

Cimetidine is a medication that is primarily used to treat ulcers in the stomach and esophagus. It works by blocking the production of stomach acid, which can help to reduce pain and inflammation associated with ulcers. Cimetidine is also sometimes used to treat other conditions, such as heartburn, GERD (gastroesophageal reflux disease), and certain types of cancer. It is available in both oral and intravenous forms, and is typically taken two to four times per day. Side effects of cimetidine may include headache, dizziness, nausea, and constipation. It is important to follow the dosage instructions provided by your healthcare provider and to let them know if you experience any side effects while taking this medication.

Omeprazole is a medication that belongs to a class of drugs called proton pump inhibitors (PPIs). It is used to treat a variety of conditions related to the digestive system, including: 1. Gastroesophageal reflux disease (GERD): This is a condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Ulcers: Omeprazole is often used to treat stomach ulcers caused by the bacteria Helicobacter pylori. 3. Zollinger-Ellison syndrome: This is a rare condition in which the stomach produces too much acid. 4. Erosive esophagitis: This is a condition in which the lining of the esophagus is damaged by stomach acid. Omeprazole works by blocking the production of stomach acid by the cells in the lining of the stomach. This helps to reduce symptoms of acid-related conditions and promote healing of the digestive tract. It is usually taken once a day, with or without food.

Ranitidine is a medication that is used to treat conditions such as heartburn, acid reflux, and stomach ulcers. It works by reducing the production of stomach acid, which can help to relieve symptoms and promote healing. Ranitidine is available in both over-the-counter and prescription forms, and it is usually taken by mouth. It is generally considered to be safe and effective when used as directed, but it can cause side effects such as headache, dizziness, and constipation. In some cases, ranitidine may interact with other medications or medical conditions, so it is important to talk to a healthcare provider before taking it.

Gastritis is a medical condition characterized by inflammation of the lining of the stomach. It can be caused by a variety of factors, including bacterial or viral infections, long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), excessive alcohol consumption, and autoimmune disorders. Symptoms of gastritis may include abdominal pain, nausea, vomiting, bloating, and loss of appetite. In severe cases, gastritis can lead to ulcers, bleeding, and perforation of the stomach lining. Treatment for gastritis depends on the underlying cause and may include medications, lifestyle changes, and in some cases, surgery.

Acetic acid is a weak organic acid that is commonly used in the medical field for various purposes. It is a colorless liquid with a characteristic sour smell and is the main component of vinegar. In the medical field, acetic acid is used as a disinfectant and antiseptic. It is effective against a wide range of microorganisms, including bacteria, viruses, and fungi. It is commonly used to clean and disinfect medical equipment, such as scalpels, needles, and syringes, to prevent the spread of infection. Acetic acid is also used in the treatment of certain medical conditions. For example, it is used in the treatment of warts and other skin growths. It is applied topically to the affected area and can cause the wart to peel off over time. In addition, acetic acid is used in the production of certain medications, such as aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). It is also used in the production of some types of plastics and other industrial products. Overall, acetic acid is a versatile compound with many uses in the medical field, including as a disinfectant, antiseptic, and medication ingredient.

In the medical field, recurrence refers to the reappearance of a disease or condition after it has been treated or has gone into remission. Recurrence can occur in various medical conditions, including cancer, infections, and autoimmune diseases. For example, in cancer, recurrence means that the cancer has come back after it has been treated with surgery, chemotherapy, radiation therapy, or other treatments. Recurrence can occur months, years, or even decades after the initial treatment. In infections, recurrence means that the infection has returned after it has been treated with antibiotics or other medications. Recurrence can occur due to incomplete treatment, antibiotic resistance, or other factors. In autoimmune diseases, recurrence means that the symptoms of the disease return after they have been controlled with medication. Recurrence can occur due to changes in the immune system or other factors. Overall, recurrence is a significant concern for patients and healthcare providers, as it can require additional treatment and can impact the patient's quality of life.

Gastrins are a family of hormones that are produced by cells in the lining of the stomach and small intestine. They play a key role in regulating the production of stomach acid and the movement of food through the digestive tract. Gastrins are also involved in the growth and development of the stomach and other digestive organs. In the medical field, gastrins are often measured as a diagnostic tool for conditions such as peptic ulcers, stomach cancer, and Zollinger-Ellison syndrome, which is a rare condition characterized by excessive production of stomach acid.

Dyspepsia is a term used in the medical field to describe a group of symptoms that affect the upper part of the digestive system, including the stomach and the small intestine. These symptoms can include: 1. Bloating or fullness after eating 2. Nausea or vomiting 3. Heartburn or acid reflux 4. Pain or discomfort in the upper abdomen 5. Loss of appetite 6. Early satiety (feeling full soon after eating) 7. Pain or discomfort that is relieved by eating or drinking something Dyspepsia can be caused by a variety of factors, including stress, certain foods or drinks, certain medications, and underlying medical conditions such as ulcers, gastritis, or gallbladder disease. Treatment for dyspepsia depends on the underlying cause and may include lifestyle changes, medication, or surgery.

Gastrointestinal hemorrhage, also known as GI bleeding, is a medical condition in which there is bleeding in the digestive tract, including the esophagus, stomach, small intestine, large intestine, rectum, or anus. The bleeding can be acute or chronic, and the severity can range from mild to life-threatening. The symptoms of gastrointestinal hemorrhage can include black or tarry stools, blood in the stool, abdominal pain, nausea, vomiting, weakness, dizziness, and fainting. The cause of gastrointestinal hemorrhage can be due to a variety of factors, including peptic ulcers, inflammatory bowel disease, gastrointestinal tumors, hemorrhoids, diverticulitis, and liver disease. Diagnosis of gastrointestinal hemorrhage typically involves a physical examination, blood tests, imaging studies such as endoscopy or colonoscopy, and sometimes angiography. Treatment of gastrointestinal hemorrhage depends on the underlying cause and the severity of the bleeding. It may include medications, endoscopic procedures, surgery, or a combination of these approaches.

Venous insufficiency is a medical condition in which the veins in the legs are unable to effectively pump blood back to the heart. This can cause blood to pool in the veins, leading to swelling, pain, and other symptoms. Venous insufficiency is often caused by damage to the valves in the veins, which can occur due to aging, obesity, pregnancy, or injury. It can also be a complication of other medical conditions, such as varicose veins or deep vein thrombosis. Treatment for venous insufficiency may include lifestyle changes, such as exercise and weight loss, as well as medications and procedures to improve blood flow and reduce symptoms.

Amoxicillin is an antibiotic medication that is commonly used to treat a variety of bacterial infections, including pneumonia, bronchitis, ear infections, urinary tract infections, and skin infections. It is a type of penicillin antibiotic that works by stopping the growth of bacteria in the body. Amoxicillin is usually taken orally in the form of tablets or capsules, and it is often prescribed for short-term use. It is important to follow the dosage instructions provided by your healthcare provider and to complete the full course of treatment, even if you start to feel better before the medication is finished. Like all antibiotics, amoxicillin can cause side effects, such as nausea, diarrhea, and allergic reactions. It is important to let your healthcare provider know if you experience any side effects while taking amoxicillin.

Dumping syndrome is a condition that occurs when food moves too quickly from the stomach to the small intestine. This can cause a variety of symptoms, including abdominal pain, bloating, nausea, diarrhea, and dizziness. Dumping syndrome can be caused by certain medical conditions, such as gastrectomy (surgery to remove part or all of the stomach), or by eating certain types of foods, such as high-fat or high-sugar foods. Treatment for dumping syndrome typically involves dietary changes and medications to slow down the movement of food through the digestive system.

Bismuth is a chemical element that is used in the medical field as an active ingredient in certain medications. It is most commonly used in combination with other medications to treat stomach ulcers and acid reflux. Bismuth also has antidiarrheal properties and has been used to treat bacterial infections, such as salmonellosis and shigellosis. In addition, bismuth has been used in the treatment of certain skin conditions, such as acne and rosacea. It is usually taken as a medication in the form of a tablet or capsule.

Esophageal diseases refer to a group of medical conditions that affect the esophagus, a muscular tube that connects the throat to the stomach. The esophagus is responsible for moving food and liquid from the mouth to the stomach. Esophageal diseases can be classified into two main categories: structural and functional. Structural esophageal diseases are those that involve changes in the physical structure of the esophagus. Examples include esophageal cancer, Barrett's esophagus, achalasia, and esophageal strictures. These conditions can cause symptoms such as difficulty swallowing, chest pain, and weight loss. Functional esophageal diseases, on the other hand, are those that involve changes in the way the esophagus functions. Examples include gastroesophageal reflux disease (GERD), eosinophilic esophagitis (EoE), and nutcracker esophagus. These conditions can cause symptoms such as heartburn, chest pain, difficulty swallowing, and difficulty breathing. Esophageal diseases can be diagnosed through a variety of tests, including endoscopy, manometry, and imaging studies such as CT scans or MRI. Treatment for esophageal diseases depends on the specific condition and may include medications, lifestyle changes, endoscopic procedures, or surgery.

Famotidine is a medication that is used to treat conditions such as heartburn, acid reflux, and stomach ulcers. It works by blocking the production of stomach acid, which helps to reduce symptoms such as heartburn and acid reflux. Famotidine is available in both over-the-counter and prescription forms, and is typically taken by mouth. It is generally considered to be safe and effective when used as directed, but like all medications, it can cause side effects in some people. Some common side effects of famotidine include headache, dizziness, and nausea.

2-Pyridinylmethylsulfinylbenzimidazoles are a class of compounds that have a benzimidazole ring with a 2-pyridinylmethylsulfinyl substituent. They are used in the medical field as potential drugs for the treatment of various diseases, including cancer, inflammation, and viral infections. Some specific examples of 2-pyridinylmethylsulfinylbenzimidazoles that have been studied in the medical field include: * BMS-790052: a drug that is being developed for the treatment of multiple myeloma, a type of cancer that affects the bone marrow. * BMS-986016: a drug that is being developed for the treatment of chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow. * BMS-986015: a drug that is being developed for the treatment of non-small cell lung cancer, a type of cancer that affects the lungs. These compounds are thought to work by inhibiting the activity of enzymes that are involved in the growth and survival of cancer cells. They are also being studied for their potential anti-inflammatory and antiviral effects.

Stomatitis, Aphthous is a medical condition that refers to the inflammation of the mucous membranes of the mouth, commonly known as canker sores. These sores are usually small, round, and shallow ulcers that can be painful and may affect the tongue, lips, gums, and roof of the mouth. Aphthous stomatitis is a common condition that affects people of all ages, and it can be caused by a variety of factors, including stress, hormonal changes, vitamin deficiencies, and certain medications. The exact cause of aphthous stomatitis is not always clear, and it can be difficult to treat, although over-the-counter pain relievers and mouthwashes can help to alleviate symptoms. In severe cases, a doctor may prescribe stronger medications or recommend lifestyle changes to help prevent future outbreaks.

Metronidazole is an antibiotic medication that is commonly used to treat a variety of bacterial and protozoal infections. It is particularly effective against anaerobic bacteria, which are bacteria that thrive in oxygen-poor environments. Metronidazole is often used to treat infections of the gastrointestinal tract, such as giardiasis and trichomoniasis, as well as infections of the vagina, skin, and respiratory tract. It is also sometimes used to treat infections caused by certain types of parasites, such as Entamoeba histolytica. Metronidazole is available in various forms, including tablets, capsules, and creams, and is typically taken orally or applied topically. It is important to follow the instructions of your healthcare provider when taking metronidazole, as it can cause side effects such as nausea, vomiting, and diarrhea.

Clarithromycin is an antibiotic medication that is used to treat a variety of bacterial infections, including pneumonia, bronchitis, skin infections, and ear infections. It is a macrolide antibiotic, which means that it works by inhibiting the growth of bacteria by interfering with their ability to make proteins. Clarithromycin is available in both oral and intravenous forms and is typically taken for a duration of 7 to 14 days, depending on the specific infection being treated. It is important to note that clarithromycin may not be effective against all types of bacteria and that it can have side effects, including nausea, diarrhea, and stomach pain.

Chancroid is a sexually transmitted infection (STI) caused by the bacterium Haemophilus ducreyi. It is characterized by the development of painful ulcers on the genitalia, which can lead to scarring and other complications if left untreated. Chancroid is most commonly transmitted through sexual contact, including vaginal, anal, and oral sex. It is less common than other STIs such as syphilis and gonorrhea, but it can still cause serious health problems if not properly diagnosed and treated. Treatment for chancroid typically involves antibiotics, and it is important to practice safe sex to prevent the spread of the infection.

Lansoprazole is a medication that belongs to a class of drugs called proton pump inhibitors (PPIs). It is used to treat a variety of conditions related to the digestive system, including: 1. Gastroesophageal reflux disease (GERD): This is a condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Ulcers: Lansoprazole is used to treat stomach ulcers caused by the bacteria Helicobacter pylori (H. pylori) and to prevent ulcers from recurring. 3. Zollinger-Ellison syndrome: This is a rare condition in which the stomach produces too much acid. Lansoprazole is used to reduce the amount of acid produced. Lansoprazole works by blocking the production of stomach acid by the cells in the lining of the stomach. This helps to reduce the symptoms of GERD, ulcers, and Zollinger-Ellison syndrome. It is usually taken once or twice a day, with or without food.

Hematemesis is a medical term that refers to the vomiting of blood or blood-stained saliva. It is a symptom of a bleeding disorder in the digestive tract, usually in the stomach or esophagus. Hematemesis can be caused by a variety of conditions, including peptic ulcers, gastritis, esophageal varices, esophageal cancer, and stomach cancer. It can also be a complication of certain medications, such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs). Hematemesis is a serious medical condition that requires prompt medical attention, as it can be a sign of a life-threatening bleeding disorder.

Pentagastrin is a synthetic peptide that stimulates the release of gastric acid and other digestive enzymes from the stomach. It is commonly used in medical research and diagnostic testing to evaluate the function of the stomach and its digestive system. Pentagastrin is typically administered intravenously or orally, and its effects can be measured through various methods, such as pH monitoring or enzyme assays. In some cases, pentagastrin may also be used to treat certain digestive disorders, although its use in this context is limited and typically reserved for cases where other treatments have been ineffective.

Magnesium hydroxide is a white, odorless powder that is commonly used in the medical field as an antacid and laxative. It is also used in some mouthwashes and toothpastes to neutralize acid and freshen breath. In the body, magnesium hydroxide works by binding to stomach acid and neutralizing it, which can help to relieve symptoms of heartburn, acid reflux, and indigestion. It can also help to soften stools and promote regular bowel movements, which makes it useful for treating constipation. Magnesium hydroxide is generally considered safe when used as directed, but it can cause side effects such as bloating, gas, and diarrhea in some people. It is important to follow the recommended dosage and to talk to a healthcare provider before using magnesium hydroxide if you have any medical conditions or are taking any medications.

Gastrointestinal (GI) diseases refer to conditions that affect the digestive system, which includes the esophagus, stomach, small intestine, large intestine, rectum, and anus. These diseases can range from minor to severe and can affect any part of the digestive system. Some common examples of gastrointestinal diseases include: 1. Gastroesophageal reflux disease (GERD): A condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Peptic ulcers: Sores that develop in the lining of the stomach or duodenum, often caused by the bacteria Helicobacter pylori. 3. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions that affect the digestive tract, including Crohn's disease and ulcerative colitis. 4. Irritable bowel syndrome (IBS): A condition characterized by abdominal pain, bloating, and changes in bowel habits that are not related to a structural problem in the digestive system. 5. Celiac disease: An autoimmune disorder in which the body reacts to gluten, a protein found in wheat, barley, and rye. 6. Diverticulitis: An inflammation of small pouches in the wall of the colon. 7. Colorectal cancer: A type of cancer that starts in the colon or rectum. 8. Gastrointestinal infections: Infections caused by bacteria, viruses, or parasites that affect the digestive system. These are just a few examples of the many gastrointestinal diseases that can affect people. Treatment for these conditions can vary depending on the specific disease and its severity.

Duodenitis is an inflammation of the duodenum, which is the first part of the small intestine. It can be caused by a variety of factors, including bacterial or viral infections, autoimmune disorders, and certain medications. Symptoms of duodenitis may include abdominal pain, nausea, vomiting, diarrhea, and weight loss. Treatment typically involves addressing the underlying cause of the inflammation and may include antibiotics, anti-inflammatory medications, or changes to the diet. In severe cases, hospitalization may be necessary.

Melena is a medical term used to describe black, tarry stools. It is a sign of gastrointestinal bleeding that has been in the digestive system for a longer period of time, usually more than 24 hours. The black color is due to the presence of blood that has been exposed to stomach acid and has undergone chemical changes. Melena can be caused by a variety of conditions, including peptic ulcers, inflammatory bowel disease, esophageal varices (swollen veins in the esophagus), and cancer of the stomach or intestines. It is a serious condition that requires prompt medical attention, as it can lead to anemia, dehydration, and other complications.

Mycobacterium infections, nontuberculous, refer to a group of infections caused by mycobacteria other than Mycobacterium tuberculosis. These infections are also known as NTM (nontuberculous mycobacteria) infections. NTM infections can affect various parts of the body, including the lungs, skin, lymph nodes, and bones. NTM infections are typically acquired through inhalation of contaminated water or soil, or through contact with infected individuals or animals. They can also occur as a result of weakened immune systems, such as in people with HIV/AIDS or those taking immunosuppressive medications. Symptoms of NTM infections can vary depending on the affected area of the body. Common symptoms include cough, fever, night sweats, weight loss, and fatigue. Infections of the lungs can also cause chest pain, shortness of breath, and。 Diagnosis of NTM infections typically involves a combination of clinical examination, imaging studies, and laboratory testing. Treatment may involve a combination of antibiotics and surgery, depending on the severity and location of the infection.

Pepsinogens are inactive precursors of the digestive enzyme pepsin, which is produced in the stomach lining. There are two main types of pepsinogens: pepsinogen A and pepsinogen B. Pepsinogen A is produced by chief cells in the stomach lining and is found in the stomach juice. Pepsinogen B is produced by parietal cells in the stomach lining and is also found in the stomach juice. Pepsinogens are activated to pepsin by hydrochloric acid, which is produced by parietal cells in the stomach lining. Pepsin then breaks down proteins in the food we eat, helping to digest them. In the medical field, pepsinogens are often measured in blood or stool samples as a way to diagnose and monitor certain conditions, such as stomach ulcers, gastritis, and Helicobacter pylori infection. High levels of pepsinogens in the blood or stool may indicate inflammation or damage to the stomach lining, while low levels may indicate a deficiency in stomach acid production.

Stomach neoplasms refer to abnormal growths or tumors that develop in the lining of the stomach. These growths can be either benign (non-cancerous) or malignant (cancerous). Stomach neoplasms can occur in different parts of the stomach, including the stomach lining, the muscular wall of the stomach, and the glands that produce stomach acid. Some common types of stomach neoplasms include gastric adenocarcinoma (a type of cancer that starts in the glandular cells of the stomach lining), gastric lymphoma (a type of cancer that starts in the lymphatic cells of the stomach), and gastric stromal tumors (benign tumors that develop in the connective tissue of the stomach). Stomach neoplasms can cause a variety of symptoms, including abdominal pain, nausea, vomiting, weight loss, and loss of appetite. Diagnosis typically involves a combination of medical history, physical examination, imaging tests (such as endoscopy or CT scan), and biopsy. Treatment for stomach neoplasms depends on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches.

Rectal diseases refer to medical conditions that affect the rectum, which is the final part of the large intestine. The rectum is responsible for storing feces until they are eliminated from the body through the anus. Rectal diseases can be acute or chronic and can range from minor to severe. Some common rectal diseases include: 1. Hemorrhoids: Swollen veins in the rectum or anus that can cause pain, itching, and bleeding. 2. Anal fissures: Tears in the lining of the anus that can cause pain and bleeding during bowel movements. 3. Fistulas: Abnormal connections between the rectum and other organs or tissues, such as the skin or vagina. 4. Polyps: Non-cancerous growths in the rectum that can cause bleeding or blockage. 5. Inflammatory bowel disease (IBD): Chronic conditions that cause inflammation in the rectum and other parts of the digestive tract, including Crohn's disease and ulcerative colitis. 6. Rectal cancer: A type of cancer that starts in the rectum and can spread to other parts of the body. Rectal diseases can be diagnosed through a physical examination, medical imaging tests, and other diagnostic procedures. Treatment options depend on the specific disease and may include medications, surgery, or other therapies.

Behcet's syndrome, also known as Behcet's disease, is a rare, chronic, and systemic inflammatory disorder that affects multiple organs and systems in the body. It is characterized by recurrent episodes of oral and genital ulcers, as well as inflammation of the eyes, skin, joints, and blood vessels. The exact cause of Behcet's syndrome is unknown, but it is thought to be an autoimmune disorder in which the immune system attacks healthy cells and tissues in the body. The symptoms of Behcet's syndrome can vary widely from person to person, and the severity of the disease can also vary over time. Treatment for Behcet's syndrome typically involves a combination of medications, including corticosteroids, immunosuppressants, and biologic agents, to reduce inflammation and prevent complications. In some cases, surgery may be necessary to treat complications such as eye damage or blood vessel inflammation.

Gangrene is a medical condition in which a part of the body dies due to a lack of blood supply. This can occur due to a blockage of blood vessels, infection, or injury. Gangrene can affect any part of the body, but it is most commonly seen in the extremities, such as the toes, fingers, and legs. There are two types of gangrene: dry and wet. Dry gangrene occurs when the affected area is pale, cool, and hard to the touch. Wet gangrene, on the other hand, occurs when the affected area is red, warm, and painful. Wet gangrene is more serious and can progress quickly if left untreated. Treatment for gangrene depends on the cause and severity of the condition. In some cases, surgery may be necessary to remove the dead tissue and promote healing. Antibiotics may also be prescribed to treat any underlying infections. In severe cases, amputation of the affected limb may be necessary to prevent the spread of infection or to save the patient's life.

In the medical field, organometallic compounds are compounds that contain a metal atom bonded to a carbon atom of an organic molecule. These compounds have a wide range of applications in medicine, including as drugs, diagnostic agents, and catalysts for various chemical reactions. One example of an organometallic compound used in medicine is cisplatin, which is a chemotherapy drug used to treat various types of cancer. Cisplatin contains a platinum atom bonded to two carbon atoms from organic molecules, and its mechanism of action involves binding to DNA and inhibiting its replication. Another example is ferrocene, which is an organometallic compound containing a ferrocene moiety. Ferrocene has been studied for its potential as a treatment for various diseases, including cancer and Alzheimer's disease, due to its ability to modulate cellular signaling pathways. Overall, organometallic compounds have a significant impact on the medical field, and ongoing research is exploring their potential for new therapeutic applications.

Foot diseases refer to a wide range of medical conditions that affect the feet and can cause pain, discomfort, and other symptoms. These conditions can be caused by a variety of factors, including genetics, injury, infection, and underlying medical conditions. Some common foot diseases include: 1. Plantar fasciitis: A condition that causes pain in the bottom of the foot, usually due to overuse or injury. 2. Bunions: A bony bump on the side of the big toe that can cause pain and swelling. 3. Athlete's foot: A fungal infection that affects the skin on the feet and can cause itching, burning, and cracking. 4. Hammer toes: A condition in which the toes become bent and curved, often due to wearing shoes that are too tight. 5. Neuromas: A benign growth of nerve tissue that can cause pain and numbness in the foot. 6. Gout: A type of arthritis that causes inflammation and pain in the joints, including the feet. 7. Peripheral artery disease: A condition in which the blood vessels in the legs and feet become narrowed or blocked, leading to pain, cramping, and other symptoms. 8. Diabetic foot ulcers: Sores or wounds on the feet that can develop in people with diabetes due to poor circulation and nerve damage. Treatment for foot diseases depends on the specific condition and may include medications, physical therapy, surgery, or other interventions. It is important to seek medical attention if you are experiencing pain or other symptoms in your feet, as many foot diseases can be prevented or treated with early intervention.

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Tongue diseases refer to any medical conditions that affect the tongue, including infections, injuries, and disorders that affect its structure or function. Some common tongue diseases include: 1. Aphthous ulcers: These are small, painful sores that can develop on the tongue, lips, or inside the cheeks. 2. Oral thrush: This is a fungal infection that can cause white patches to form on the tongue and inside the mouth. 3. Geographic tongue: This is a condition in which the surface of the tongue develops red, smooth patches that can be itchy or painful. 4. Burning mouth syndrome: This is a chronic condition that causes a burning sensation in the mouth, including the tongue. 5. Leukoplakia: This is a white or gray patch on the tongue or inside the mouth that can be a sign of cancer. 6. Oral lichen planus: This is a chronic inflammatory condition that can cause white or gray patches on the tongue and inside the mouth. 7. Oral cancer: This is a type of cancer that can develop on the tongue or in other parts of the mouth. Tongue diseases can be caused by a variety of factors, including infections, allergies, hormonal changes, and certain medications. Treatment for tongue diseases depends on the underlying cause and may include medications, lifestyle changes, or surgery.

Duodenal diseases refer to medical conditions that affect the duodenum, which is the first part of the small intestine. The duodenum is responsible for receiving and mixing food from the stomach with digestive enzymes and bile from the liver and gallbladder. Some common duodenal diseases include: 1. Duodenal ulcers: These are sores that develop in the lining of the duodenum or the stomach. They are often caused by the bacteria Helicobacter pylori and can lead to bleeding, pain, and other complications. 2. Duodenal diverticulosis: This is a condition in which small pouches or sacs form in the wall of the duodenum. It is usually asymptomatic but can cause complications such as bleeding, infection, and blockage. 3. Duodenal cancer: This is a rare type of cancer that develops in the cells lining the duodenum. It can cause symptoms such as abdominal pain, weight loss, and changes in bowel habits. 4. Duodenal strictures: These are narrowing or blockages in the duodenum that can be caused by inflammation, scarring, or other factors. They can lead to symptoms such as abdominal pain, vomiting, and difficulty swallowing. 5. Duodenal polyps: These are small growths that develop on the lining of the duodenum. Most are harmless, but some can be precancerous or lead to bleeding. Treatment for duodenal diseases depends on the specific condition and its severity. It may include medications, lifestyle changes, endoscopic procedures, or surgery.

Skin diseases caused by bacteria are a common type of infection that can affect people of all ages and genders. These infections can range from mild to severe and can affect different parts of the body, including the face, neck, arms, legs, and torso. Some common bacterial skin diseases include acne, impetigo, cellulitis, folliculitis, and erysipelas. Acne is a common skin condition that affects the hair follicles and sebaceous glands, causing pimples, blackheads, and whiteheads. Impetigo is a highly contagious skin infection that usually affects children and is caused by the bacteria Streptococcus pyogenes or Staphylococcus aureus. Cellulitis is a serious skin infection that can spread quickly and cause swelling, redness, and pain. Folliculitis is an infection of the hair follicles that can cause redness, swelling, and pus-filled bumps. Erysipelas is a severe skin infection that can cause redness, swelling, and fever. Treatment for bacterial skin diseases typically involves the use of antibiotics, either topically or orally, depending on the severity of the infection. In some cases, hospitalization may be necessary for severe infections. It is important to seek medical attention if you suspect you have a bacterial skin infection, as untreated infections can lead to complications and spread to other parts of the body.

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, reduce inflammation, and lower fever. It works by blocking the production of prostaglandins, which are chemicals that cause pain, inflammation, and fever. Indomethacin is available in various forms, including tablets, capsules, and suppositories. It is often prescribed for conditions such as arthritis, menstrual cramps, and headaches. It can also be used to treat gout, kidney stones, and other inflammatory conditions. However, indomethacin can have side effects, including stomach pain, nausea, vomiting, and diarrhea. It can also increase the risk of bleeding and ulcers in the stomach and intestines. Therefore, it is important to use indomethacin only as directed by a healthcare provider and to report any side effects immediately.

Cysteamine is a medication that is used to treat certain genetic disorders, such as cystinosis and homocystinuria. It works by reducing the amount of cystine in the body, which can help to prevent the buildup of cystine crystals in the kidneys and other organs. Cysteamine is usually taken by mouth in the form of tablets or capsules, and it may be taken in combination with other medications. It is important to follow the instructions of your healthcare provider when taking cysteamine, as the dosage and duration of treatment may vary depending on the specific condition being treated.

Aluminum hydroxide is a white, odorless, and tasteless powder that is commonly used in the medical field as an antacid and an adsorbent. It works by neutralizing stomach acid and reducing symptoms of heartburn, indigestion, and acid reflux. In addition to its use as an antacid, aluminum hydroxide is also used in the treatment of hyperphosphatemia, a condition characterized by high levels of phosphate in the blood. It works by binding to phosphate and preventing it from being absorbed by the body. Aluminum hydroxide is available over-the-counter as well as by prescription. It is generally considered safe when used as directed, but long-term use at high doses may increase the risk of aluminum toxicity, which can lead to neurological and bone problems.

Diabetic neuropathy is a type of nerve damage that can occur as a complication of diabetes. It is caused by damage to the nerves that control movement, sensation, and other functions in the body. There are several types of diabetic neuropathy, including: 1. Peripheral neuropathy: This is the most common type of diabetic neuropathy and affects the nerves in the extremities, such as the hands, feet, and legs. It can cause numbness, tingling, pain, and weakness in the affected areas. 2. Autonomic neuropathy: This type of neuropathy affects the nerves that control automatic bodily functions, such as heart rate, digestion, and blood pressure. It can cause symptoms such as dizziness, fainting, and gastrointestinal problems. 3. Proximal neuropathy: This type of neuropathy affects the nerves in the arms and legs, causing weakness and muscle wasting in the affected areas. 4. Mononeuropathy: This is a type of neuropathy that affects a single nerve, causing symptoms such as pain, numbness, and weakness in the affected area. Diabetic neuropathy can be a serious complication of diabetes and can lead to a range of problems, including foot ulcers, infections, and even amputations. It is important for people with diabetes to manage their blood sugar levels and to see their healthcare provider regularly for monitoring and treatment.

Urease is an enzyme that catalyzes the hydrolysis of urea to produce ammonia and carbon dioxide. It is produced by various microorganisms, including bacteria, fungi, and some plants. In the medical field, urease is often used as a diagnostic tool to identify the presence of certain microorganisms in clinical samples, such as urine, sputum, and stool. This is because many pathogenic bacteria, such as Helicobacter pylori and Klebsiella pneumoniae, produce urease and can be detected using urease-based tests. Additionally, urease inhibitors are sometimes used in the treatment of certain medical conditions, such as peptic ulcers and kidney stones, by blocking the action of urease and reducing the production of ammonia.

Zollinger-Ellison Syndrome (ZES) is a rare disorder characterized by the excessive production of stomach acid, also known as hypersecretion of gastric acid. This condition is caused by the presence of a tumor, usually a gastrinoma, in the pancreas or duodenum, which secretes excessive amounts of the hormone gastrin. The excessive production of stomach acid can lead to a variety of symptoms, including frequent heartburn, ulcers, and acid reflux. In severe cases, it can cause life-threatening complications such as bleeding ulcers, perforation of the stomach or duodenum, and acid-induced damage to the esophagus. ZES is typically diagnosed through a combination of medical tests, including blood tests to measure gastrin levels, imaging studies such as endoscopy or CT scans, and sometimes surgery to remove the tumor. Treatment for ZES typically involves medications to reduce stomach acid production, such as proton pump inhibitors, and in some cases, surgery to remove the tumor or block the hormone-secreting cells.

Eye infections caused by bacteria are a common type of eye infection that can affect people of all ages. These infections can cause a range of symptoms, including redness, swelling, itching, discharge, and sensitivity to light. Bacterial eye infections can affect the surface of the eye (conjunctivitis) or the inside of the eye (endophthalmitis). Conjunctivitis is the most common type of bacterial eye infection and can be caused by a variety of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus. Endophthalmitis is a more serious infection that can cause vision loss and is typically treated with antibiotics administered directly into the eye. Bacterial eye infections are usually treated with antibiotics, which can be taken orally or applied directly to the eye. In some cases, additional treatment may be necessary to manage symptoms or prevent complications. It is important to seek medical attention if you suspect you have a bacterial eye infection, as prompt treatment can help prevent the infection from spreading and reduce the risk of complications.

Ileal diseases refer to medical conditions that affect the ileum, which is the final section of the small intestine. The ileum is responsible for absorbing nutrients from digested food and eliminating waste products from the body. Some common ileal diseases include: 1. Ileitis: Inflammation of the ileum, which can be caused by a variety of factors such as infections, autoimmune disorders, or inflammatory bowel disease. 2. Ileal Crohn's disease: A type of inflammatory bowel disease that affects the ileum and can cause inflammation, ulcers, and strictures. 3. Ileal tuberculosis: A rare form of tuberculosis that affects the ileum and can cause inflammation, ulcers, and abscesses. 4. Ileal lymphoma: A type of cancer that affects the ileum and can cause inflammation, ulcers, and blockages. 5. Ileal diverticulitis: Inflammation of small pouches (diverticula) that form in the lining of the ileum. 6. Ileal polyps: Non-cancerous growths that can form in the lining of the ileum. 7. Ileal strictures: Narrowing of the ileum that can cause blockages and digestive problems. Treatment for ileal diseases depends on the underlying cause and can include medications, surgery, or a combination of both.

A wound infection is an infection that occurs in a cut, scrape, or surgical incision. It can be caused by bacteria, viruses, fungi, or other microorganisms that enter the body through the wound. Symptoms of a wound infection may include redness, swelling, warmth, pain, pus, and a foul odor. If left untreated, a wound infection can lead to serious complications, such as sepsis, which is a life-threatening condition that can cause organ failure and even death. Treatment for a wound infection typically involves antibiotics, wound cleaning and dressing changes, and in some cases, surgery. It is important to seek medical attention if you suspect you have a wound infection to prevent further complications.

Eye infections caused by fungi are a common type of ocular infection. Fungal eye infections can affect the cornea, conjunctiva, or eyelids. Symptoms of fungal eye infections may include redness, itching, burning, discharge, and sensitivity to light. Treatment for fungal eye infections typically involves the use of antifungal medications, such as topical creams or ointments, or oral medications. In severe cases, surgery may be necessary to remove the infected tissue. It is important to seek medical attention if you suspect you have a fungal eye infection, as untreated infections can lead to serious complications, such as vision loss.

Postoperative complications are adverse events that occur after a surgical procedure. They can range from minor issues, such as bruising or discomfort, to more serious problems, such as infection, bleeding, or organ damage. Postoperative complications can occur for a variety of reasons, including surgical errors, anesthesia errors, infections, allergic reactions to medications, and underlying medical conditions. They can also be caused by factors such as poor nutrition, dehydration, and smoking. Postoperative complications can have serious consequences for patients, including prolonged hospital stays, additional surgeries, and even death. Therefore, it is important for healthcare providers to take steps to prevent postoperative complications and to promptly recognize and treat them if they do occur.

Pepsin A is a digestive enzyme that is produced in the lining of the stomach. It is responsible for breaking down proteins into smaller peptides and amino acids, which can then be absorbed by the body. Pepsin A is activated by hydrochloric acid, which is also produced in the stomach, and is typically secreted in an inactive form called pepsinogen. Once it is activated, pepsin A has a pH optimum of around 2, which is the acidic environment of the stomach. It is an important part of the digestive process and is involved in the breakdown of many different types of proteins, including those found in meat, dairy products, and eggs.

Rabeprazole is a medication that belongs to a class of drugs called proton pump inhibitors (PPIs). It is used to treat a variety of conditions related to the digestive system, including: 1. Gastroesophageal reflux disease (GERD): a condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Duodenal ulcers: sores in the lining of the small intestine. 3. Gastric ulcers: sores in the lining of the stomach. 4. Helicobacter pylori (H. pylori) infection: a bacterial infection that can cause ulcers in the stomach and duodenum. 5. Zollinger-Ellison syndrome: a rare condition in which the stomach produces too much acid. Rabeprazole works by blocking the production of stomach acid, which helps to reduce symptoms and promote healing of the digestive lining. It is usually taken by mouth, either as a tablet or a liquid, and is usually taken once or twice a day, depending on the condition being treated.

Ischemia is a medical condition that occurs when there is a lack of blood flow to a particular part of the body. This can happen when the blood vessels that supply blood to the affected area become narrowed or blocked, either due to a physical obstruction or a decrease in blood pressure. Ischemia can affect any part of the body, but it is most commonly associated with the heart and brain. In the heart, ischemia can lead to a condition called angina, which is characterized by chest pain or discomfort. If the blood flow to the heart is completely blocked, it can result in a heart attack. In the brain, ischemia can cause a stroke, which can lead to permanent damage or even death if not treated promptly. Ischemia can also occur in other organs, such as the kidneys, limbs, and intestines, and can cause a range of symptoms depending on the affected area. Treatment for ischemia typically involves addressing the underlying cause of the blockage or narrowing of the blood vessels, such as through medication, surgery, or lifestyle changes.

Vulvar diseases refer to a group of medical conditions that affect the vulva, which is the external female genitalia. The vulva includes the labia majora, labia minora, clitoris, vaginal opening, and Bartholin's glands. Vulvar diseases can be classified into several categories, including infections, inflammatory conditions, neoplastic conditions, and others. Some common vulvar diseases include: 1. Vulvovaginal candidiasis: A fungal infection caused by the Candida species. 2. Bacterial vaginosis: A condition characterized by an imbalance of bacteria in the vagina. 3. Genital herpes: A viral infection that can cause painful sores on the vulva. 4. Vulvar eczema: A skin condition that causes redness, itching, and inflammation of the vulva. 5. Vulvar cancer: A rare but serious condition that can develop in the cells of the vulva. 6. Vulvar varicosities: Swollen veins in the vulva. 7. Vulvar vestibulitis syndrome: A condition characterized by inflammation and pain in the opening of the vagina. Vulvar diseases can cause discomfort, pain, and other symptoms, and may require medical treatment. It is important for women to be aware of the signs and symptoms of vulvar diseases and to seek medical attention if they experience any concerning symptoms.

Hydrochloric acid (HCl) is a strong acid that is commonly used in the medical field for various purposes. It is a clear, colorless liquid that has a strong, pungent odor and a sour taste. In the medical field, hydrochloric acid is used as a digestive aid to stimulate the production of stomach acid, which helps to break down food and absorb nutrients. It is also used as a disinfectant and antiseptic to clean wounds and prevent infection. In addition, hydrochloric acid is used in some medical tests and procedures, such as the measurement of gastric acid secretion and the treatment of certain digestive disorders. However, it is important to note that hydrochloric acid can be highly corrosive and can cause serious burns if it comes into contact with the skin or mucous membranes. Therefore, it should be handled with caution and used only under the supervision of a qualified healthcare professional.

Thromboangiitis obliterans, also known as Buerger's disease, is a rare inflammatory disorder that affects the blood vessels in the arms and legs. It is characterized by the formation of blood clots and inflammation in the walls of the blood vessels, which can lead to pain, numbness, and tissue damage in the affected limbs. The condition is more common in young men and is often associated with smoking. Treatment typically involves medications to prevent blood clots and surgery to remove damaged tissue or bypass blocked blood vessels.

Osteomyelitis is a type of bone infection that occurs when bacteria enter the bone and cause inflammation and damage to the bone tissue. It can affect any bone in the body, but it is most commonly seen in the long bones of the arms and legs, as well as in the spine and pelvis. Osteomyelitis can be acute or chronic, and it can be caused by a variety of factors, including bacterial infections, fungal infections, and viral infections. It can also be caused by traumatic injuries, such as fractures or punctures, or by medical procedures, such as surgery or the insertion of a catheter. Symptoms of osteomyelitis may include fever, chills, fatigue, and pain in the affected bone. In some cases, there may be no symptoms at all until the infection has progressed significantly. Treatment for osteomyelitis typically involves antibiotics to kill the bacteria causing the infection. In some cases, surgery may be necessary to remove infected tissue or to drain abscesses. Physical therapy may also be recommended to help restore strength and mobility to the affected bone.

Iodophors are antiseptic solutions that contain iodine as the active ingredient. They are commonly used in the medical field for disinfection and sterilization of surfaces, equipment, and skin. Iodophors are effective against a wide range of microorganisms, including bacteria, viruses, and fungi. They are particularly useful for disinfecting areas that are difficult to clean, such as wounds and catheters. Iodophors are available in various forms, including gels, sprays, and solutions, and are typically used at dilutions of 1-10 parts per million (ppm). It is important to follow proper use instructions and precautions when using iodophors to avoid skin irritation and other adverse effects.

Carbenoxolone is a medication that is used to treat peptic ulcers, a condition in which the lining of the stomach or duodenum (the first part of the small intestine) is damaged. It works by reducing the production of stomach acid and by increasing the production of a substance called prostaglandin, which helps to protect the stomach lining. Carbenoxolone is available in the form of tablets and is usually taken two to four times a day, with or without food. It is important to follow the instructions of your healthcare provider when taking this medication.

Penicillins are a group of antibiotics that are derived from the Penicillium fungi. They are one of the most widely used antibiotics in the medical field and are effective against a variety of bacterial infections, including pneumonia, strep throat, and urinary tract infections. Penicillins work by inhibiting the production of cell walls in bacteria, which causes the bacteria to burst and die. There are several different types of penicillins, including penicillin G, penicillin V, amoxicillin, and cephalosporins, which have different properties and are used to treat different types of infections. Penicillins are generally well-tolerated by most people, but can cause side effects such as allergic reactions, diarrhea, and nausea. It is important to take penicillins exactly as prescribed by a healthcare provider and to finish the full course of treatment, even if symptoms improve before the medication is finished.

Furazolidone is an antibiotic medication that is used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, and skin infections. It works by inhibiting the growth of bacteria and is often used in combination with other antibiotics to increase its effectiveness. Furazolidone is available in both oral and topical forms and is generally well-tolerated by most people. However, like all antibiotics, it can cause side effects such as nausea, diarrhea, and allergic reactions. It is important to take Furazolidone exactly as prescribed by a healthcare provider and to complete the full course of treatment, even if symptoms improve before the medication is finished.

Penile diseases refer to medical conditions that affect the structure or function of the penis. These conditions can range from minor to severe and can affect both the physical and sexual health of a person. Some common penile diseases include: 1. Erectile dysfunction: A condition where a person is unable to achieve or maintain an erection sufficient for sexual activity. 2. Peyronie's disease: A condition where the penis becomes curved due to the formation of scar tissue. 3. Phimosis: A condition where the foreskin of the penis is too tight to be retracted over the glans (head) of the penis. 4. Balanitis: An inflammation of the glans or foreskin of the penis. 5. Chlamydia: A sexually transmitted infection (STI) that can cause inflammation of the urethra, prostate, and other reproductive organs. 6. Gonorrhea: Another STI that can cause inflammation of the urethra, prostate, and other reproductive organs. 7. Herpes: A viral infection that can cause sores or blisters on the penis. 8. Cancer: Rarely, penile cancer can occur, which can be treated with surgery, radiation therapy, or chemotherapy. It is important to note that penile diseases can have a significant impact on a person's quality of life and should be treated promptly by a healthcare professional.

Tuberculosis, Oral refers to a form of tuberculosis that affects the mouth and throat. It is a rare form of the disease, accounting for less than 1% of all tuberculosis cases. The symptoms of oral tuberculosis may include ulcers in the mouth or throat, difficulty swallowing, hoarseness, and weight loss. The disease is usually spread through the air when an infected person coughs or sneezes. Diagnosis of oral tuberculosis typically involves a combination of physical examination, medical history, and laboratory tests such as sputum culture or biopsy. Treatment usually involves a combination of antibiotics taken for several months, and may also include surgery to remove infected tissue. It is important to note that oral tuberculosis is a serious condition that requires prompt diagnosis and treatment to prevent complications and spread to other parts of the body.

Pyloric stenosis is a condition in which the opening between the stomach and small intestine (pylorus) becomes narrowed or blocked, leading to difficulty in emptying the stomach contents into the small intestine. This can cause a build-up of pressure in the stomach, leading to symptoms such as vomiting, abdominal pain, and dehydration. Pyloric stenosis is most commonly seen in infants, particularly those between 2 and 8 weeks of age. It is usually treated with surgery to widen the pylorus and relieve the blockage.

Arthropathy, neurogenic refers to a type of arthritis that is caused by damage to the nerves that control the muscles and joints in the body. This damage can be caused by a variety of conditions, including spinal cord injuries, multiple sclerosis, and peripheral neuropathy. In neurogenic arthropathy, the nerves that control the muscles and joints in the affected area become damaged, leading to muscle weakness, stiffness, and pain. This can cause the joints to become misaligned or deformed, leading to further pain and disability. Treatment for neurogenic arthropathy typically involves managing the underlying condition that is causing the nerve damage, as well as using physical therapy, pain management techniques, and assistive devices to help manage symptoms and improve function. In some cases, surgery may be necessary to correct joint deformities or relieve pressure on the affected nerves.

Plant extracts refer to the active compounds or bioactive molecules that are extracted from plants and used in the medical field for various therapeutic purposes. These extracts are obtained through various extraction methods, such as solvent extraction, steam distillation, and cold pressing, and can be used in the form of powders, liquids, or capsules. Plant extracts have been used for centuries in traditional medicine and are now widely used in modern medicine as well. They are used to treat a wide range of conditions, including inflammation, pain, anxiety, depression, and cancer. Some examples of plant extracts used in medicine include aspirin (extracted from willow bark), quinine (extracted from cinchona bark), and morphine (extracted from opium poppy). Plant extracts are also used in the development of new drugs and therapies. Researchers extract compounds from plants and test them for their potential therapeutic effects. If a compound shows promise, it can be further developed into a drug that can be used to treat a specific condition. It is important to note that while plant extracts can be effective in treating certain conditions, they can also have side effects and may interact with other medications. Therefore, it is important to consult with a healthcare professional before using plant extracts as a form of treatment.

Guanidines are organic compounds that contain the guanidinium group, which is composed of a nitrogen atom bonded to three carbon atoms and one hydrogen atom. In the medical field, guanidines are often used as drugs or as intermediates in the synthesis of other drugs. One example of a guanidine drug is procainamide, which is used to treat certain types of arrhythmias (irregular heartbeats). Another example is hydralazine, which is used to treat high blood pressure. Guanidines are also used as intermediates in the synthesis of other drugs, such as the antiviral drug zidovudine (AZT). Guanidines can have a variety of effects on the body, depending on the specific compound and how it is used. For example, procainamide can block sodium channels in the heart, which can help regulate heart rate and rhythm. Hydralazine works by relaxing blood vessels, which can help lower blood pressure. It is important to note that guanidines can also have side effects, and their use should be closely monitored by a healthcare provider. Some common side effects of guanidines include nausea, vomiting, headache, and dizziness. In some cases, guanidines can also cause more serious side effects, such as allergic reactions or liver damage.

Tinidazole is an antibiotic medication used to treat a variety of bacterial and protozoal infections. It is a member of the nitroimidazole class of antibiotics and works by inhibiting the growth and reproduction of microorganisms. Tinidazole is commonly used to treat infections of the digestive tract, such as giardiasis (an infection caused by the parasite Giardia lamblia) and trichomoniasis (a sexually transmitted infection caused by the parasite Trichomonas vaginalis). It may also be used to treat infections of the skin, respiratory tract, and urinary tract. Tinidazole is available in various forms, including tablets, capsules, and oral suspension. It is usually taken orally, with or without food, as directed by a healthcare provider. Side effects of tinidazole may include nausea, vomiting, diarrhea, abdominal pain, and headache. It is important to follow the dosage instructions provided by a healthcare provider and to complete the full course of treatment, even if symptoms improve before the medication is finished.

Misoprostol is a medication that is used to prevent and treat a number of conditions related to the uterus and the digestive system. It is a synthetic prostaglandin E1 analog that is commonly used to induce labor and to treat uterine contractions in pregnant women who are at risk of a miscarriage or who are experiencing a threatened abortion. Misoprostol is also used to treat stomach ulcers and to prevent bleeding in women who have had a dilation and curettage (D&C) procedure to remove tissue from the uterus. It is usually taken orally or vaginally, and its effects can be felt within 30 minutes to an hour. Misoprostol is a relatively safe medication, but it can cause side effects such as nausea, vomiting, diarrhea, and abdominal pain. It is important to follow the instructions of a healthcare provider when taking misoprostol, as the dosage and frequency of use can vary depending on the condition being treated.

Cyclooxygenase 1 (COX-1) is an enzyme that plays a crucial role in the production of prostaglandins, which are hormone-like substances that regulate various physiological processes in the body, including inflammation, pain, and blood clotting. COX-1 is found in most tissues throughout the body, including the stomach, blood vessels, and kidneys. In the medical field, COX-1 is often targeted for the treatment of various conditions, including pain, inflammation, and gastrointestinal disorders. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen are commonly used to inhibit COX-1 activity, which can help reduce pain and inflammation. However, long-term use of high doses of NSAIDs can also lead to side effects such as stomach ulcers and increased risk of cardiovascular events. COX-1 is also involved in the production of thromboxanes, which are potent vasoconstrictors that can contribute to the formation of blood clots. As a result, COX-1 inhibitors have been developed for the treatment of conditions such as hypertension and cardiovascular disease. However, these drugs can also increase the risk of bleeding, particularly in patients taking anticoagulant medications.

Gastritis, Atrophic is a medical condition characterized by the inflammation of the lining of the stomach, specifically the atrophic type. This type of gastritis is caused by a decrease in the production of stomach acid and digestive enzymes, which can lead to the destruction of the lining of the stomach. Atrophic gastritis is often associated with a lack of stomach acid, which can lead to a condition called hypochlorhydria. This can cause symptoms such as abdominal pain, bloating, nausea, and vomiting. In severe cases, atrophic gastritis can lead to the development of stomach cancer. Atrophic gastritis is typically diagnosed through a combination of medical history, physical examination, and diagnostic tests such as endoscopy and biopsy. Treatment may include medications to increase stomach acid production, dietary changes, and in some cases, surgery.

Barium sulfate is a white, odorless powder that is commonly used in medical imaging procedures, particularly in X-ray imaging. It is also known as barium meal or barium contrast medium. When consumed or administered intravenously, barium sulfate coats the walls of the gastrointestinal tract, making it easier to see on an X-ray. This allows doctors to examine the digestive system for abnormalities such as ulcers, tumors, or inflammation. Barium sulfate is also used in other medical procedures, such as bronchography (to examine the airways) and cystography (to examine the urinary system). It is important to note that barium sulfate can cause allergic reactions in some people, and it should only be used under the supervision of a qualified healthcare professional.

A gastric fistula is a abnormal connection between the stomach and another body cavity or organ, such as the esophagus, small intestine, colon, or chest. It can occur as a complication of surgery, trauma, or infection, and can lead to the leakage of stomach contents into the surrounding area, causing inflammation, infection, and other complications. Treatment options for gastric fistulas depend on the underlying cause and severity of the condition, and may include surgery, medications, and nutritional support.

In the medical field, acetates refer to compounds that contain the acetate ion (CH3COO-). Acetates are commonly used in the treatment of various medical conditions, including: 1. Hyperkalemia: Acetate is used to treat high levels of potassium (hyperkalemia) in the blood. It works by binding to potassium ions and preventing them from entering cells, which helps to lower potassium levels in the blood. 2. Acidosis: Acetate is used to treat acidosis, a condition in which the blood becomes too acidic. It works by increasing the production of bicarbonate ions, which helps to neutralize excess acid in the blood. 3. Respiratory failure: Acetate is used to treat respiratory failure, a condition in which the lungs are unable to provide enough oxygen to the body. It works by providing an alternative source of energy for the body's cells, which helps to support the respiratory system. 4. Metabolic acidosis: Acetate is used to treat metabolic acidosis, a condition in which the body produces too much acid. It works by increasing the production of bicarbonate ions, which helps to neutralize excess acid in the body. 5. Hyperammonemia: Acetate is used to treat hyperammonemia, a condition in which the blood contains too much ammonia. It works by providing an alternative source of energy for the body's cells, which helps to reduce the production of ammonia. Overall, acetates are a useful tool in the treatment of various medical conditions, and their use is closely monitored by healthcare professionals to ensure their safe and effective use.

Prostaglandin-endoperoxide synthases, also known as cyclooxygenases (COXs), are enzymes that play a crucial role in the production of prostaglandins and thromboxanes, which are hormone-like substances that regulate various physiological processes in the body. There are two main isoforms of COX: COX-1 and COX-2. COX-1 is constitutively expressed in most tissues and is involved in the maintenance of normal physiological functions, such as platelet aggregation, gastric mucosal protection, and renal blood flow regulation. In contrast, COX-2 is induced in response to various stimuli, such as inflammation, injury, and stress, and is primarily involved in the production of prostaglandins that mediate inflammatory and pain responses. Prostaglandins and thromboxanes are synthesized from arachidonic acid, a polyunsaturated fatty acid that is released from membrane phospholipids in response to various stimuli. COXs catalyze the conversion of arachidonic acid to prostaglandin H2 (PGH2), which is then further metabolized to various prostaglandins and thromboxanes by other enzymes. In the medical field, COX inhibitors are commonly used as anti-inflammatory and analgesic drugs. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen are examples of COX inhibitors that are widely used to treat pain, inflammation, and fever. However, long-term use of NSAIDs can have adverse effects on the gastrointestinal tract and cardiovascular system, which has led to the development of newer COX-2 selective inhibitors, such as celecoxib and rofecoxib, that are thought to have fewer gastrointestinal side effects.

Tetragastrin is a hormone that is produced by the stomach. It is a peptide hormone that is composed of four amino acids: glutamic acid, aspartic acid, alanine, and glycine. Tetragastrin is involved in the regulation of gastric acid secretion and has been shown to stimulate the production of hydrochloric acid in the stomach. It is also thought to play a role in the regulation of appetite and food intake. In the medical field, tetragastrin is sometimes used as a diagnostic tool to help diagnose conditions that affect gastric acid secretion, such as Zollinger-Ellison syndrome.

Sulfoxides are a class of organic compounds that contain a sulfur-oxygen double bond (S=O). They are derivatives of sulfides, which have a sulfur-sulfur double bond (S=S). Sulfoxides are commonly used in the medical field as intermediates in the synthesis of other drugs and as anticonvulsants, antioxidants, and anti-inflammatory agents. They are also used as reagents in organic chemistry reactions. Some sulfoxides have been studied for their potential use in the treatment of cancer, but their effectiveness as anticancer agents is still being investigated.

Cyclooxygenase 2 (COX-2) is an enzyme that is involved in the production of prostaglandins, which are hormone-like substances that play a role in various physiological processes in the body, including inflammation, pain, and fever. COX-2 is primarily found in cells of the immune system and in the lining of the gastrointestinal tract. In the medical field, COX-2 inhibitors are a class of drugs that are used to reduce inflammation and relieve pain. They are often prescribed for conditions such as arthritis, menstrual cramps, and headaches. However, long-term use of COX-2 inhibitors has been associated with an increased risk of cardiovascular events, such as heart attacks and strokes, which has led to some restrictions on their use.

In the medical field, silver compounds refer to substances that contain silver as an active ingredient. Silver has been used in medicine for centuries due to its antimicrobial properties, which means it can kill or inhibit the growth of microorganisms such as bacteria, viruses, and fungi. Silver compounds are used in a variety of medical applications, including wound care, burn treatment, and the prevention of infections. Some common silver compounds used in medicine include silver sulfadiazine, silver nitrate, and silver chloride. Silver sulfadiazine is a cream or ointment that is commonly used to treat burns and other skin injuries. It contains silver ions that help to prevent the growth of bacteria and other microorganisms that can cause infections. Silver nitrate is a solution that is used to treat eye infections, such as conjunctivitis. It contains silver ions that help to kill bacteria and other microorganisms that can cause infections in the eye. Silver chloride is a powder that is used to treat wounds and other skin injuries. It contains silver ions that help to prevent the growth of bacteria and other microorganisms that can cause infections. Overall, silver compounds are an important tool in the medical field for preventing and treating infections. However, it is important to note that silver compounds can also have side effects and may not be suitable for everyone. It is always important to consult with a healthcare professional before using any medical treatment.

Carnosine is a dipeptide composed of alanine and histidine. It is found in high concentrations in skeletal muscle, brain, and other tissues. Carnosine has been studied for its potential health benefits, including its ability to protect against oxidative stress, reduce inflammation, and improve muscle function. In the medical field, carnosine has been used to treat conditions such as age-related muscle wasting, cognitive decline, and certain types of eye disease. It is also used as a dietary supplement to enhance athletic performance and improve overall health.

Herpes genitalis, also known as genital herpes, is a sexually transmitted infection (STI) caused by the herpes simplex virus (HSV). There are two types of herpes simplex virus: HSV-1 and HSV-2. HSV-1 is typically associated with oral herpes, while HSV-2 is more commonly associated with genital herpes. Herpes genitalis is characterized by painful sores or blisters on the genital area, including the vagina, vulva, penis, scrotum, and anus. These sores can be itchy, painful, and may take several weeks to heal. In some cases, the virus can remain dormant in the body and cause recurrent outbreaks of sores. Herpes genitalis is highly contagious and can be transmitted through sexual contact, including vaginal, anal, and oral sex. It can also be transmitted from mother to child during childbirth. There is no cure for herpes genitalis, but antiviral medications can help manage symptoms and reduce the frequency and severity of outbreaks. It is important for individuals with herpes genitalis to practice safe sex to prevent transmission to sexual partners.

Aortic diseases refer to a group of medical conditions that affect the aorta, which is the largest artery in the human body. The aorta carries oxygen-rich blood from the heart to the rest of the body. Aortic diseases can be congenital (present at birth) or acquired (developing over time). Some common aortic diseases include: 1. Aortic aneurysm: A bulge or dilation in the wall of the aorta that can rupture and cause life-threatening bleeding. 2. Aortic dissection: A tear in the inner lining of the aorta that can cause blood to flow between the layers of the artery, leading to severe pain and potential organ damage. 3. Aortic stenosis: Narrowing of the aortic valve that can restrict blood flow from the heart to the rest of the body. 4. Aortic regurgitation: Backflow of blood from the aorta into the heart due to a damaged or insufficient aortic valve. 5. Marfan syndrome: A genetic disorder that affects the connective tissue and can lead to aortic aneurysms and dissections. 6. Ehlers-Danlos syndrome: A group of genetic disorders that can affect the connective tissue and increase the risk of aortic aneurysms and dissections. Treatment for aortic diseases depends on the specific condition and its severity. In some cases, medications or lifestyle changes may be sufficient, while in others, surgery or other medical procedures may be necessary. Early detection and treatment are crucial for preventing complications and improving outcomes.

Spinal cord injuries (SCI) are a type of injury that occurs when the spinal cord is damaged or disrupted, usually as a result of trauma or disease. The spinal cord is a bundle of nerves that runs down the back of the neck and lower back, and it is responsible for transmitting signals between the brain and the rest of the body. When the spinal cord is injured, it can result in a range of symptoms, depending on the location and severity of the injury. These can include loss of sensation or movement in the affected area, difficulty with bladder or bowel control, and changes in sexual function. SCI can be caused by a variety of factors, including car accidents, falls, sports injuries, and acts of violence. Treatment for SCI typically involves a combination of medical and rehabilitative care, and the goal is to help individuals with SCI regain as much function as possible and improve their quality of life.

Jejunal diseases refer to medical conditions that affect the jejunum, which is the middle part of the small intestine. The jejunum is responsible for absorbing nutrients from digested food, and any disease that affects this part of the digestive system can lead to a range of symptoms and complications. Some common jejunal diseases include: 1. Jejunoileal Atresia: This is a birth defect in which the jejunum and ileum (the last part of the small intestine) do not connect properly, leading to malnutrition and other complications. 2. Jejunal Perforation: This occurs when a hole develops in the jejunum, allowing digestive contents to leak into the abdominal cavity. This can be caused by trauma, infection, or other factors. 3. Jejunal Ulcer: This is a sore or lesion that develops in the lining of the jejunum. It can be caused by a variety of factors, including infection, inflammation, or injury. 4. Jejunal Diverticulosis: This is a condition in which small pouches or sacs form in the lining of the jejunum. These sacs can become inflamed or infected, leading to pain, fever, and other symptoms. 5. Jejunal Cancer: This is a rare type of cancer that develops in the lining of the jejunum. It can cause a range of symptoms, including abdominal pain, weight loss, and changes in bowel habits. Treatment for jejunal diseases depends on the specific condition and its severity. In some cases, surgery may be necessary to remove damaged tissue or repair a perforation. Medications, such as antibiotics or anti-inflammatory drugs, may also be used to manage symptoms or treat underlying conditions.

A digestive system fistula is a abnormal connection between two organs or between an organ and the skin that allows the flow of digestive fluids or contents between them. This can occur as a result of injury, infection, or surgery, and can lead to a variety of symptoms, including abdominal pain, diarrhea, and malnutrition. Treatment options for digestive system fistulas depend on the underlying cause and the severity of the condition, and may include medications, surgery, or other interventions.

Histamine is a chemical substance that is produced by certain cells in the body, including immune cells and cells in the digestive system. It plays a role in a variety of physiological processes, including the contraction of smooth muscles, the dilation of blood vessels, and the stimulation of nerve endings. In the medical field, histamine is often used as a diagnostic tool to help identify conditions such as allergies, asthma, and certain types of infections. It is also used as a treatment for certain conditions, such as allergic reactions and certain types of digestive disorders.

Gastric outlet obstruction (GOO) is a medical condition in which there is a blockage or narrowing of the passage through which food and liquid pass from the stomach to the small intestine. This can be caused by a variety of factors, including tumors, inflammation, or scar tissue. Symptoms of GOO may include nausea, vomiting, abdominal pain, and weight loss. Treatment options for GOO depend on the underlying cause and may include medications, endoscopic procedures, or surgery.

Postgastrectomy syndromes (PGS) are a group of conditions that can occur after a person has undergone a gastrectomy, which is the surgical removal of the stomach. These conditions can include symptoms such as nausea, vomiting, abdominal pain, and diarrhea. PGS can be caused by a variety of factors, including changes in the digestive system after surgery, the use of certain medications, and the presence of other medical conditions. Treatment for PGS typically involves managing symptoms and addressing any underlying causes.

Gastric mucins are a type of complex glycoprotein that are produced by cells in the lining of the stomach. They are important for protecting the stomach lining from the highly acidic environment of the stomach and for preventing the stomach from digesting itself. Gastric mucins are also involved in the immune response of the stomach and play a role in the formation of mucus plugs that help to protect the stomach from harmful substances. In medical research, gastric mucins are often studied in the context of diseases such as gastric cancer and peptic ulcers.

Bacterial proteins are proteins that are synthesized by bacteria. They are essential for the survival and function of bacteria, and play a variety of roles in bacterial metabolism, growth, and pathogenicity. Bacterial proteins can be classified into several categories based on their function, including structural proteins, metabolic enzymes, regulatory proteins, and toxins. Structural proteins provide support and shape to the bacterial cell, while metabolic enzymes are involved in the breakdown of nutrients and the synthesis of new molecules. Regulatory proteins control the expression of other genes, and toxins can cause damage to host cells and tissues. Bacterial proteins are of interest in the medical field because they can be used as targets for the development of antibiotics and other antimicrobial agents. They can also be used as diagnostic markers for bacterial infections, and as vaccines to prevent bacterial diseases. Additionally, some bacterial proteins have been shown to have therapeutic potential, such as enzymes that can break down harmful substances in the body or proteins that can stimulate the immune system.

Corneal perforation is a medical condition in which a hole or tear is created in the cornea, which is the clear, dome-shaped outer layer of the eye. This can occur due to various reasons, including trauma, infection, or surgery. A corneal perforation can cause significant vision loss and pain, and if left untreated, can lead to serious complications such as endophthalmitis (infection of the inner eye) or glaucoma. Treatment options for corneal perforation depend on the cause and severity of the injury, and may include antibiotics, surgery to repair the perforation, or the use of artificial tears to lubricate the eye.

Esomeprazole is a proton pump inhibitor (PPI) medication that is used to treat a variety of conditions related to the digestive system, including gastroesophageal reflux disease (GERD), ulcers, and Zollinger-Ellison syndrome. It works by reducing the production of stomach acid, which can help to relieve symptoms and promote healing in the digestive tract. Esomeprazole is available in both prescription and over-the-counter forms, and it is typically taken by mouth once or twice a day, depending on the condition being treated. It is usually taken with food to help reduce stomach upset. Side effects of esomeprazole may include headache, nausea, diarrhea, and stomach pain. In rare cases, it may cause more serious side effects, such as allergic reactions or changes in liver function. It is important to talk to a healthcare provider about any potential risks or side effects before starting treatment with esomeprazole.

Systemic Scleroderma, also known as Scleroderma, is a chronic autoimmune disorder that affects the connective tissue in the body. It causes the skin and internal organs to become hard and inflexible, leading to a range of symptoms and complications. The exact cause of Systemic Scleroderma is not known, but it is believed to be triggered by an abnormal immune response that causes the body's own tissues to be attacked and damaged. The disease can affect people of all ages and ethnicities, but it is more common in women than in men. Symptoms of Systemic Scleroderma can vary widely depending on the severity and location of the disease. Common symptoms include skin thickening and hardening, Raynaud's phenomenon (a condition that causes the fingers and toes to turn white or blue when exposed to cold), joint pain and stiffness, digestive problems, and lung fibrosis (scarring of the lungs). Treatment for Systemic Scleroderma typically involves a combination of medications, physical therapy, and lifestyle changes. Medications may include immunosuppressants, corticosteroids, and disease-modifying antirheumatic drugs (DMARDs). Physical therapy can help to improve flexibility and reduce pain, while lifestyle changes such as quitting smoking and maintaining a healthy weight can help to slow the progression of the disease.

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It is transmitted through direct contact with an infected person's sores or other mucous membranes during sexual activity, including vaginal, anal, and oral sex. Syphilis can also be transmitted from mother to child during pregnancy or childbirth. Syphilis has three stages: primary, secondary, and tertiary. The primary stage is characterized by a single, painless sore called a chancre, usually on the genital area, anus, or mouth. The secondary stage can occur weeks to months after the initial infection and is characterized by a rash on the skin and mucous membranes, fever, swollen lymph nodes, and sore throat. The tertiary stage, which can occur years after the initial infection, can cause serious damage to the heart, brain, and other organs. Syphilis can be diagnosed through a blood test, and treatment typically involves antibiotics. If left untreated, syphilis can lead to serious health complications and even death. It is important to practice safe sex and get tested regularly for sexually transmitted infections.

Stomatitis, Herpetic, also known as Herpes Simplex Virus (HSV) Stomatitis, is a viral infection that affects the mouth and throat. It is caused by the Herpes Simplex Virus (HSV), which is a common virus that can be transmitted through direct contact with an infected person's skin or mucous membranes. The symptoms of Herpes Simplex Virus Stomatitis include painful sores or blisters on the lips, tongue, gums, and inside of the cheeks. The blisters may be painful and can break open, forming ulcers that can take several weeks to heal. Other symptoms may include fever, headache, and swollen lymph nodes in the neck. Herpes Simplex Virus Stomatitis is usually self-limiting, meaning that it will resolve on its own within a few weeks without any specific treatment. However, antiviral medications can help to reduce the severity and duration of symptoms, as well as prevent the virus from spreading to other people. It is important to note that Herpes Simplex Virus Stomatitis is highly contagious and can be spread through kissing, sharing eating utensils or drinking glasses, and other forms of close contact. Therefore, it is important to practice good hygiene and avoid close contact with others until the symptoms have resolved.

Granuloma Inguinale, also known as Donovanosis, is a sexually transmitted infection caused by the bacterium Calymmatobacterium granulomatis. It primarily affects the genital and perianal regions, but can also occur in other areas of the body. The infection is characterized by the development of painful, ulcerative lesions that can be accompanied by swelling, redness, and tenderness.,Granuloma Inguinale,、、、。

In the medical field, pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain is a complex phenomenon that involves both physical and emotional components, and it can be caused by a variety of factors, including injury, illness, inflammation, and nerve damage. Pain can be acute or chronic, and it can be localized to a specific area of the body or can affect the entire body. Acute pain is typically short-lived and is a normal response to injury or illness. Chronic pain, on the other hand, persists for more than three months and can be caused by a variety of factors, including nerve damage, inflammation, and psychological factors. In the medical field, pain is typically assessed using a pain scale, such as the Visual Analog Scale (VAS), which measures pain intensity on a scale of 0 to 10. Treatment for pain depends on the underlying cause and can include medications, physical therapy, and other interventions.

Intestinal perforation is a medical condition in which there is a hole or tear in the wall of the intestine. This can occur due to various causes, such as trauma, infection, or underlying medical conditions such as inflammatory bowel disease or cancer. When the wall of the intestine perforates, the contents of the intestine can leak out into the surrounding tissue, causing an infection called peritonitis. This can be a life-threatening condition if not treated promptly. Symptoms of intestinal perforation may include severe abdominal pain, fever, nausea and vomiting, and a fast heart rate. Diagnosis is typically made through imaging studies such as X-rays or CT scans, and treatment may involve surgery to repair the perforation and remove any infected tissue.

Colonic diseases refer to a group of medical conditions that affect the colon, which is the final part of the large intestine. The colon is responsible for absorbing water and electrolytes from the remaining food matter in the digestive tract, and it also plays a role in the formation of feces. Colonic diseases can be broadly classified into two categories: inflammatory and non-inflammatory. Inflammatory colonic diseases include inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis. Non-inflammatory colonic diseases include diverticulitis, polyps, and colon cancer. Inflammatory colonic diseases are characterized by chronic inflammation of the colon, which can lead to symptoms such as abdominal pain, diarrhea, and rectal bleeding. Non-inflammatory colonic diseases, on the other hand, are not associated with inflammation and can have a variety of symptoms depending on the specific condition. Colonic diseases can be diagnosed through a combination of medical history, physical examination, and diagnostic tests such as colonoscopy, sigmoidoscopy, and barium enema. Treatment for colonic diseases depends on the specific condition and may include medications, dietary changes, and in some cases, surgery.

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Patients may feel pain on the skin around the ulcer, and fluid may ooze from the ulcer. In some cases, ulcers can bleed and, ... This stress in the blood circulation is transformed to a skin ulcer, commonly known as bedsores or decubitus ulcers. Ulcers ... Different types of discharges from ulcer are: Serous, usually seen in healing ulcer Purulent, seen in infected ulcer. Yellow ... An ulcer that appears on the skin is often visible as an inflamed tissue with an area of reddened skin. A skin ulcer is often ...
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... cutting around the ulcer, removing both the ulcer and the surrounding inflamed tissue). Some ulcers may recur in the same ... Hunner's ulcers can only be accurately diagnosed via a cystoscopy, and at the same time can be treated with hydrodistention. ... Hunner's ulcers or Hunner's lesions occur in 5 to 10 percent of people who have the bladder disease interstitial cystitis. They ... Elmiron has also led to long term eye damage from use.[citation needed] The ulcers can be removed through fulguration (burned ...
Stress ulcers tend to present with multiple lesions whereas in peptic ulcers this much more uncommon. Stress ulcers, as defined ... The term stress ulcer is a proper medical term and should not be misinterpreted as indicating that this ulcers are caused by ... These ulcers are a significant issue in patients in critical and intensive care. It was previously thought that peptic ulcers ( ... Whereas ordinary peptic ulcers are found commonly in the gastric antrum and the duodenum, stress ulcers are usually found in ...
... venous ulcers, ulcers from osteomyelitis, and post radiotherapy scars. The term was named after French surgeon, Jean-Nicolas ... Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, ... Marjolin's ulcer". N. Engl. J. Med. 352 (10): e9. doi:10.1056/NEJMicm040020. PMID 15758002. Paredes F (February 1998). "[ ... Slow growth, painlessness (as the ulcer is usually not associated with nerve tissue), and absence of lymphatic spread due to ...
A genital ulcer may be located on the vulva, penis, perianal region, or anus. Globally, the incidence of genital ulcers is ... Important signs associated with genital ulcers that may assist in the diagnosis of the cause of the genital ulcer may include ... Other potential causes of non-infectious genital ulcers are diverse, but can include sexual trauma, Lipschutz ulcers, ... or Perianal Ulcers, Centers for Disease Control and Prevention Diagnosis and Management of Genital Ulcers, American Family ...
Category III is for an ulcer larger than 15 centimeters, multiple ulcers, or ulcers that have spread to include particularly ... Ulcers are most common on the lower limbs (roughly 62% of ulcers globally) and upper limbs (24%), but can also be found on the ... Buruli ulcer does not spread from one person to another. In areas endemic for Buruli ulcer, disease occurs near stagnant bodies ... Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability. Buruli ulcer is caused by skin ...
... may refer to: Carcinomatous ulcer, an ulcer with cancerous pathology behind it Rodent ulcer, also known as ... A historical term for necrotizing fasciitis This disambiguation page lists articles associated with the title Malignant ulcer. ...
... or Necrotic Angiodermatitis is a painful ulceration of the lower leg associated with diastolic arterial ... The syndrome occurs predominantly in middle-aged women with poorly controlled hypertension in the form of skin ulcers on the ... The pathophysiology of the Martorell ulcer is assumed to be related to hypertension-induced arteriole changes in the dermis. ... It was first identified by the Spanish cardiologist Fernando Martorell in 1945, who referred to the ulcers as 'hypertensive ...
Pressure ulcers are also painful, with individuals of all ages and all stages of pressure ulcers reporting pain.[citation ... Pressure ulcers from a medical device are classified according to the same classification system being used for pressure ulcers ... "Preventing Pressure Ulcers in Hospitals". Archived from the original on 7 June 2012. Retrieved 8 June 2012. "Pressure ulcers in ... National Pressure Ulcer Advisory Panel (U.S.), European Pressure Ulcer Advisory Panel, Pan Pacific Pressure Injury Alliance) ( ...
Kangri ulcers are a cutaneous condition prevalent among the poorer classes of Kashmir, and a consequence of wearing warm embers ... Marjolin's ulcer Peat fire cancer List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007 ... ISBN 978-1-4160-2999-1. MARJOLIN'S ULCER OF THE SCALP: CASE REPORT AND LITERATURE REVIEW. Malheiro E., Pinto A., Choupina M., ...
These ulcers may form individually or multiple ulcers may appear at once (i.e., a "crop" of ulcers). Once formed, an ulcer may ... A mouth ulcer (aphtha) is an ulcer that occurs on the mucous membrane of the oral cavity. Mouth ulcers are very common, ... A mucosal ulcer is an ulcer which specifically occurs on a mucous membrane. An ulcer is a tissue defect which has penetrated ... Herpetiform ulcers begin as small blisters (vesicles) which break down into 2-3mm sized ulcers. Herpetiform ulcers appear in " ...
An ulcer is a medical condition caused by a break in a bodily membrane. Ulcer or ulceration may also refer to: Ulcer ( ... Look up ulcer or ulceration in Wiktionary, the free dictionary. ... an American industrial metal band Ulcer index, a stock market ... analysis indicator devised by Peter Martin in 1987 This disambiguation page lists articles associated with the title Ulcer. If ...
A Cushing ulcer, named after Harvey Cushing, is a gastric ulcer associated with elevated intracranial pressure. It is also ... As Cushing ulcers have a higher incidence of developing after shock, sepsis or trauma, diagnosis should include recent medical ... The mechanism of development of Cushing ulcers is thought to be due to direct stimulation of vagal nuclei as a result of ... Both endoscopy and angiography can be used to locate the lesion or ulcer, though endoscopy is more commonly used as a first- ...
A venous ulcer is typically shallow with irregular sloping edges whereas an arterial ulcer can be deep and has a 'punched out' ... Venous ulcers are typically 'wet' with a moderate to heavy exudate, whereas arterial ulcers are typically 'dry' and scabbed. ... Good outcomes in ulcer treatment were shown after the application of double compression stockings, e.g. ulcer stockings. These ... Other comorbidities may also be the root cause of venous ulcers. It is in the crus that the classic venous stasis ulcer occurs ...
... is a chronic nonhealing ulcer with hard indurated base and inelastic margins. It usually contains unhealthy pale ... These ulcers generally follows neurological problems like leprosy, peripheral nerve injury, or diabetic neuropathy.[citation ... needed] Chronic ulcer "Mosby's Medical Dictionary". Retrieved 15 June 2013. Bhat, Sriram (2013). Srb's Manual of Surgery, 4e. ...
Refractory corneal ulcers are superficial ulcers that heal poorly and tend to recur. They are also known as indolent ulcers or ... Superficial ulcers involve a loss of part of the epithelium. Deep ulcers extend into or through the stroma and can result in ... Melting ulcers are a type of corneal ulcer involving progressive loss of stroma in a dissolving fashion. This is most commonly ... Refractory corneal ulcers can take a long time to heal, sometimes months. In case of progressive or non-healing ulcers, ...
... is also defined as a special and the most common type of peripheral ulcerative keratitis (PUK). Symptoms of ... Mooren's ulcer is a rare idiopathic ocular disorder that may lead to blindness due to progressive destruction of the peripheral ... To diagnose Mooren's ulcer, it is necessary to rule out other forms of non-infectious peripheral ulcerative keratitis. Topical ... In view of rarity and limited knowledge of the etiology of Mooren's ulcer, the diagnosis of the disease is complicated.The ...
... is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a ... It results in fresh bleeding per rectum (i.e. hematochezia). These ulcers may be seen on imaging, such as a CT scan but are ... Stercoral ulcers can lead to a complication known as stercoral colitis. Stercoral colitis is a relatively rare form of ... These patients may even have blood on their rectal exam, due to passing small amounts of stool around the ulcer and adjacent ...
The name pre-dates the discovery that most gastric ulcers are caused by a bacterium rather than stress.) The term ulcer index ... The ulcer index can replace the SD to make an ulcer performance index (UPI) or Martin ratio, U P I = R e t u r n − R i s k F r ... U l c e r = R 1 2 + R 2 2 + ⋯ R N 2 N {\displaystyle Ulcer={\sqrt {R_{1}^{2}+R_{2}^{2}+\cdots R_{N}^{2} \over N}}} The squares ... The ulcer index is a stock market risk measure or technical analysis indicator devised by Peter Martin in 1987, and published ...
... can occur at any age, in children however they are rare. Most common symptoms are abdominal pain and hematochezia ... Scholia has a topic profile for Colonic ulcer. v t e v t e (Abdominal pain, All stub articles, Disease stubs, Digestive system ... Maire, F.; Cellier, C.; Cervoni, J. P.; Danel, C.; Barbier, J. P.; Landi, B. (November 1998). "[Dieulafoy colonic ulcer. A rare ...
Hematopoietic ulcers are those occurring with sickle cell anemia, congenital hemolytic anemia, polycythemia vera, ...
... , ulcus vulvae acutum or reactive non-sexually related acute genital ulcers (English: acute ulceration of the ... deep ulcer (although several smaller ulcers may occur) in the internal surface of one or both labia minora. The labia majora ... Lipschütz' ulcer at Who Named It? Retrieved on 2009-12-04. Braun-Falco O, Plewig G, Wolff HH, Burgdorf WH, Landthaler M, eds. ( ... Lipschütz ulcer is named after Benjamin Lipschütz, who first described it in 1912. The cause is still unknown, although it has ...
Cushing ulcer Pruitt, Basil A. Jr.; F.D. Foley & John A. Moncrief (October 1970). "Curling's ulcer: a clinical-pathology study ... Curling's ulcer is an acute gastric erosion resulting as a complication from severe burns when reduced plasma volume leads to ... June 1972). "Curling's ulcer in children: a 12-year review of 63 cases". Journal of Trauma. 12 (6): 490-6. doi:10.1097/00005373 ... These stress ulcers (actually shallow multiple erosions) were once a common complication of serious burns, presenting in over ...
A special type of ischemic ulcer developing in duodenum after severe burns is called Curling's ulcer. The ulcers are caused by ... Arterial insufficiency ulcers (also known as ischemic ulcers, or ischemic wounds) are mostly located on the lateral surface of ... Neuropathic ulcer Gangrene Infected wound The prevalence of arterial insufficiency ulcers among people with Diabetes is high ... These ulcers are difficult to heal by basic wound care and require advanced therapy, such as hyperbaric oxygen therapy or ...
... is an ulceration of the nose similar to trigeminal trophic lesions, and has been reported ...
... except pressure ulcer 707.14 Ulcer of heel and midfoot 707.15 Ulcer of other part of foot 707.19 Ulcer of other part of lower ... 1. A surface ulcer involves full skin thickness, but does not yet involve the underlying tissues. 2. A deep ulcer penetrates ... 56 percent of individuals with foot ulcers who do not have an amputations survive for 5 years. Foot ulcers and amputations ... Stem cell therapy may represent a treatment for promoting healing of diabetic foot ulcers. Diabetic foot ulcers develop their ...
An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most ... Also, when severe ulcers resist treatment, particularly if a person has several ulcers or the ulcers are in unusual places, a ... Also, the symptoms of peptic ulcers may vary with the location of the ulcer and the person's age. Furthermore, typical ulcers ... Duodenum (called duodenal ulcer) Esophagus (called esophageal ulcer) Stomach (called gastric ulcer) Meckel's diverticulum ( ...
Buruli ulcer is a disease caused by the bacterium Mycobacterium ulcerans. It mainly affects the skin but can also affect the ... Buruli ulcer is a disease caused by the bacterium Mycobacterium ulcerans. It mainly affects the skin but can also affect the ... Infection often leads to ulcers on the arms or legs, which can also destroy skin or soft tissue. When not properly treated, the ...
Peptic ulcer disease affects 10% of men and 4% of women in the United States at some time in their lives. A peptic ulcer is a ... mucosal break of greater than or equal to 3 mm in size with depth, that can involve the stomach (gastric ulcer) or duodenum ( ...
Read about tests that help detect stomach ulcers and get relief for your belly. ... Dull and burning stomach pain are common symptoms of a peptic ulcer. ... Peptic Ulcer Disease (American Academy of Family Physicians) Also in Spanish * Peptic Ulcer Disease (American College of ... ClinicalTrials.gov: Duodenal Ulcer (National Institutes of Health) * ClinicalTrials.gov: Peptic Ulcer (National Institutes of ...
... also known as Bairnsdale ulcer, Daintree ulcer, Mossman ulcer, and Searl ulcer, is a chronic, indolent, necrotizing disease of ... Buruli ulcer is the third most common mycobacterial disease of the immunocompetent host, after tuberculosis and leprosy It is ... Other names for this entity include Bairnsdale ulcer, Daintree ulcer, Mossman ulcer, and Searl ulcer. Note the image below. ... Buruli ulcers are traditionally thought to be painless ulcers. Research has shown that the hypoalgesic effect occurs via ...
When autocomplete results are available use up and down arrows to review and enter to select. ...
... Go to external page http://purl.obolibrary.org/obo/HP_0000155 Copy ...
They are a type of peptic ulcer disease. Stomach ulcers occur when the thick layer of mucus that protects your stomach from ... Stomach ulcers are painful sores in the lining of the stomach. ... Types of Ulcers. Ulcers are open sores that can appear on any ... Stomach ulcers are a type of peptic ulcer disease. Peptic ulcers are any ulcers that affect both the stomach and small ... Gastric and duodenal ulcers are both types of peptic ulcers. These ulcers can cause different symptoms, depending on where they ...
Buruli ulcer (BU), or Mycobacterium ulcerans disease, is a severe bacterial infection that affects the skin, soft tissues and ... Buruli ulcer often starts as a painless swelling or nodule on the arms or legs. The nodules then develop into large ulcers, or ... These other conditions include tropical phagedenic ulcers, chronic lower leg ulcers due to arterial and venous insufficiency ( ... often in the older and elderly populations), diabetic ulcers, cutaneous leishmaniasis, extensive ulcerative yaws and ulcers ...
Learn more about tongue ulcers, including their symptoms, causes, and treatment, and how to identify them. ... Tongue ulcers are whiteish sores on the tongue. Also called canker sores, a 2019 article. notes that these ulcers most often ... What are mouth ulcers and what types of mouth ulcer are most common? Learn about the symptoms, causes, prevention, and ... Some forms of ulcers on the tongue and in the mouth may be signs of oral cancer. Anyone with concerns about their symptoms ...
Peptic ulcers are common, but mostly affect adults. Most can be cured. ... Ulcers in the stomach are also called stomach ulcers or gastric ulcers. Those in the duodenum are also called duodenal ulcers. ... What Is an Ulcer?. An ulcer is an open, painful sore. Peptic ulcers affect the stomach and the upper part of the small ... What Causes an Ulcer?. Most peptic ulcers are caused by:. *bacteria called Helicobacter pylori (or H. pylori) infecting the ...
... was better than a standard absorbent dressing for healing diabetic foot ulcers in a phase 3 study that led to approval by the ... The subgroup of patients at higher risk of poor wound healing (A1c , 9%, ulcer area , 5 cm2, and diabetic foot ulcer duration ... Most (78%) of the diabetic foot ulcers were Wagner grade 2. The wounds had a mean area of 4.8 cm2 and had been present for a ... If the foot ulcer does not respond, growth factors, tissue-engineering products, hyperbaric oxygen, or negative pressure wound ...
Guidelines on the Prevention of Foot Ulcers in Persons With Diabetes (IWGDF 2023 Update) Jun 11, 2023 ... This guideline provides recommendation for the prevention, assessment, and management of pressure ulcers in adults and children ... Recommendations on various interventions for the prevention of foot ulcers with corresponding rationale. ...
Ulcers can be shallow or deep and can destroy the skin or the membrane where they develop. Ulcers can be caused by some types ... An ulcer is a sore that develops on the skin (such as the skin around the ankles) or on a mucous membrane (such as inside the ... An ulcer is a sore that develops on the skin (such as the skin around the ankles) or on a mucous membrane (such as inside the ... Ulcers can be caused by some types of infection, injury, or cancer. ...
Helicobacter pylori in peptic ulcer disease: NIH Consensus Development Panel on Helicobacter pylori in peptic ulcer disease. ... that eating spicy foods caused ulcers; and 27% (95% CI=25%-29%), that a bacterial infection caused ulcers. The belief that ... These materials also are available from CDC, telephone (888) 698-5237 ({888} MY-ULCER). References. References * Sonnenberg A. ... Knowledge About Causes of Peptic Ulcer Disease -- United States, March-April 1997 MMWR 46(42);985-987 Publication date: 10/24/ ...
Core tip: Penetrating peptic ulcers (PPU) represent an extremely rare cause of abdominal pain, and can sometimes manifest with ... Here we report an extremely rare case of a duodenal ulcer penetrating the pancreas and complicated with EP. Unlike the classic ... Emphysematous pancreatitis associated with penetrating duodenal ulcer Claudio Tana, Mauro Silingardi, Maria Adele Giamberardino ... Emphysematous pancreatitis associated with penetrating duodenal ulcer. World J Gastroenterol 2017; 23(48): 8666-8670 [PMID: ...
A 37-year-old woman originally presented in May 2003 with a nonhealing, painless ulcer on the plantar surface of her right foot ... There was no significant difference in age, sex, body mass index, and duration or type of diabetes between the ulcer and ... There was a trend toward elevation of glycosylated hemoglobin (HbA1c fraction) or HbA1c in the ulcer group (p = 0.06). The ... The role of nonenzymatic glycosylation and pressure beneath the sole of the foot in the pathogenesis of neuropathic foot ulcers ...
... Aug 29, 2018 at 5:17 AM EDT ... But despite their efforts, his skin lesions developed into necrotic ulcers and the mans left forearm was amputated 25 days ...
Mylan (MYL) announced today that its American-based business issued a voluntary nationwide recall for its ulcer medication ... Nizatidine is used primarily as a treatment for stomach ulcers, but also can be prescribed for heartburn as well as ... Mylan Issues Nationwide Recall for Contaminated Ulcer Medication. By Mark Prvulovic - Jan 8, 2020 at 3:48PM ...
The course of peptic ulcer disease ranges from spontaneous resolution to the development of potentially serious complications, ... Peptic ulcers are defects in the gastrointestinal (GI) mucosa that extend through the muscularis mucosae into deeper layers of ... In uncomplicated peptic ulcer disease (PUD), the clinical findings are few and nonspecific. Upper abdominal pain is the most ... Fast Five Quiz: Review Key Aspects of Peptic Ulcer Disease - Medscape - May 11, 2017. ...
Corneal ulcer, Pekingese. Corneal ulceration with malacia and secondary anterior uveitis in the eye of a Pekingese dog. The ... photograph shows dense, perilimbal corneal vascularization, diffuse corneal edema, and a large corneal ulcer with white ...
Read about the symptoms, diagnosis and treamen of canine ulcers. ... Dog Ulcer Symptoms. Symptoms of canine ulcers include: *Lack of ... Dog Ulcer Treatments and Medicine for Canine Ulcers. Treatment of a dog stomach ulcer involves understanding and correcting the ... A dog ulcer is a sore on the skin or on mucous membranes. Most often when we talk about ulcers, we are referring to a small ... Your vet may recommend a special diet for a dog ulcer.. Medicine for Canine Ulcers include acid blocking medication. ...
Behçet Disease Complicated by a Perforated Ileal Ulcer Presenting as an Acute Abdominal Emergency. Tsai, Hong-Ming MD; Lin, Bo- ... Behçet Disease Complicated by a Perforated Ileal Ulcer Presenting as an Acute Abdominal Emergency : JCR: Journal of Clinical ... Behçet Disease Complicated by a Perforated Ileal Ulcer Presenting as an Acute Abdominal Emergency ...
Get the most up to date information on recognizing and treating equine gastric and colonic ulcers, which are more common than ... Ulcers are essentially intestinal sores that wont heal. Two types affect the horses gastrointestinal system: gastric ulcers ... Ulcers can result when this process is altered.. Long-term NSAID administration and stress appear to be the main culprits in ... EQUINE COLONIC ULCERS. Food is passed from the stomach to the hindgut, or large intestine, which includes the cecum and colon. ...
Patients develop pressure ulcers during admissions to long-term or acute care settings, which can be costly. Learn more at ... Patient positioners stop pressure ulcers before they happen Patient positioners stop pressure ulcers before they happen. ... Avoid pressure ulcers with patient positioners. Hospitals and practices of every size cannot ignore the physical and financial ... While the severity of these incidents vary from stage I to IV, each pressure ulcer may cost upwards of $120,000 to treat. As ...
ulcer of skin symptom/finding detailed information in Haz-Map database. ...
Missouri: $75,000 Settlement for Detainees Death Due to Untreated Ulcer Loaded on April 2, 2018 published in Prison Legal News ... After he was found dead in his cell on August 30, an autopsy determined his death was caused by a perforated peptic ulcer. ... Missouri: $75,000 Settlement for Detainees Death Due to Untreated Ulcer. *Global Tel*Link Settles Mississippi Prison Bribery ... rights action alleging denial of medical care to a pretrial detainee who died from complications related to a peptic ulcer. The ...
Peptic Ulcer - complications Peptic Ulcer Hemorrhage - etiology - mortality Postoperative Complications - classification - ... Lethal outcome was registered in 220 (24.6%) patients, of them directly of the ulcer bleeding died 45 (5%). The Rockall score ... Of 164 lethal outcomes, did not directly connected to the ulcer bleeding, the etiological distribution was as follows: multiple ... The retrospective analysis (2006-2010 yy) of treatment of 895 patients with gastroduodenal ulcer bleeding was conducted. ...
They are: Gastric ulcers, which form in the lining of the stomach. Duodenal ulcers, which form in the upper small intestine. ... Both types of peptic ulcers are most commonly caused either by infection with Helicobacter pylori ( H. pylori) bacteria or by ... There are two different types of peptic ulcers. ...
  • Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. (medlineplus.gov)
  • Peptic ulcers will get worse if not treated. (medlineplus.gov)
  • Antacids and milk can't heal peptic ulcers. (medlineplus.gov)
  • Peptic ulcers are any ulcers that affect both the stomach and small intestines. (healthline.com)
  • This syndrome is suspected to cause less than 1 percent of all peptic ulcers. (healthline.com)
  • Peptic ulcers affect the stomach and the upper part of the small intestine, called the duodenum (pronounced: doo-uh-DEE-num). (kidshealth.org)
  • Peptic ulcers are common, but mostly affect adults. (kidshealth.org)
  • What Are the Signs & Symptoms of Peptic Ulcers? (kidshealth.org)
  • Can Peptic Ulcers Be Prevented? (kidshealth.org)
  • Peptic ulcers are open sores that form along the digestive tract on the esophagus (esophageal ulcers), upper portion of the small intestines (duodenal ulcers), and the stomach (gastric ulcers). (earthclinic.com)
  • Peptic ulcers are defects in the gastrointestinal (GI) mucosa that extend through the muscularis mucosae into deeper layers of the intestinal wall. (medscape.com)
  • Stomach ulcers, which are also known as gastric ulcers, are painful sores in the stomach lining. (healthline.com)
  • Ulcers in the stomach are also called stomach ulcers or gastric ulcers. (kidshealth.org)
  • Gastric ulcers are caused by excess stomach acid. (dog-health-guide.org)
  • Two types affect the horse's gastrointestinal system: gastric ulcers are lesions in the stomach wall, while colonic ulcers form in the hindgut, specifically, as the name suggests, in the colon. (horse-canada.com)
  • Horses can suffer from both simultaneously, but gastric ulcers occur more regularly. (horse-canada.com)
  • This is where most gastric ulcers form. (horse-canada.com)
  • Signs of gastric ulcers may be non-existent or quite subtle. (horse-canada.com)
  • A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. (medlineplus.gov)
  • Stomach ulcers occur when digestive acids damage your stomach lining. (healthline.com)
  • What is a stomach ulcer? (healthline.com)
  • Stomach ulcers are a type of peptic ulcer disease. (healthline.com)
  • Stomach ulcers occur when the thick layer of mucus that protects your stomach from digestive juices is reduced. (healthline.com)
  • This allows the digestive acids to eat away at the tissues that line the stomach, causing an ulcer. (healthline.com)
  • Stomach ulcers may be easily cured, but they can become severe without proper treatment. (healthline.com)
  • What causes stomach ulcers? (healthline.com)
  • Rarely, a condition known as Zollinger-Ellison syndrome can cause stomach and intestinal ulcers by increasing the body's production of acid. (healthline.com)
  • A number of symptoms are associated with stomach ulcers. (healthline.com)
  • Talk with a doctor if you have any symptoms of a stomach ulcer. (healthline.com)
  • How are stomach ulcers diagnosed? (healthline.com)
  • To diagnose a stomach ulcer, your doctor will review your medical history along with your symptoms and any prescription or over-the-counter medications you're taking. (healthline.com)
  • If your stomach ulcer is the result of H. pylori , you'll need antibiotics and drugs called proton pump inhibitors (PPIs) . (healthline.com)
  • Smoking increases the risk of ulcers because nicotine causes the stomach to make more acid. (kidshealth.org)
  • Stomach pain is the most common sign of an ulcer. (kidshealth.org)
  • If you have stomach pain or other symptoms of an ulcer, the doctor will do some tests. (kidshealth.org)
  • The doctors can see the lining of the esophagus, stomach, and duodenum to check for possible ulcers. (kidshealth.org)
  • Acetaminophen does not cause stomach ulcers and is a good alternative to NSAIDs. (kidshealth.org)
  • An ulcer is a sore that develops on the skin (such as the skin around the ankles) or on a mucous membrane (such as inside the mouth, stomach, or intestines). (wellspan.org)
  • Stress from work or other aspects of life can cause the stomach to over-produce acid, which can wear away at the lining of the digestive tract, but it is now believed that most ulcers are actually caused by bacterial infections (H. pilori) and regular use of medications irritating the stomach lining. (earthclinic.com)
  • While the number one symptom of ulcers is burning pain caused by stomach acid interacting with the affected area, able to be felt anywhere between the navel and breastbone, other symptoms of ulcers include unexplained weight loss, changes in appetite, dark blood in stools, nausea, and if vomiting red or black blood. (earthclinic.com)
  • Let us know what you try from Earth Clinic to cure your stomach ulcer. (earthclinic.com)
  • Nizatidine is used primarily as a treatment for stomach ulcers, but also can be prescribed for heartburn as well as gastroesophageal reflux disease (GERD), which occurs when acid from the stomach flows back into the esophagus. (fool.com)
  • Your vet will perform a thorough physical examination and then order a number of tests for your dog in order to make a diagnosis of a dog stomach ulcers. (dog-health-guide.org)
  • Treatment of a dog stomach ulcer involves understanding and correcting the underlying cause combined with supportive care. (dog-health-guide.org)
  • If the canine gastrointestinal ulcer does not respond to medications, the veterinarian may recommend that a biopsy be taken to in the stomach and small bowel to determine if a neoplasm or cancerous growth is the problem. (dog-health-guide.org)
  • Because the lower stomach still produces acid even when the horse isn't eating, prolonged periods without saliva, which is the upper stomach's only buffer against acid, cause irritation and potentially ulcers. (horse-canada.com)
  • Buruli ulcer is a disease caused by the bacterium Mycobacterium ulcerans . (cdc.gov)
  • Buruli ulcer, caused by Mycobacterium ulcerans , is a chronic, debilitating, necrotizing disease of the skin and soft tissue. (medscape.com)
  • Buruli ulcer is an emerging infectious disease and is the third most common mycobacterial disease of the immunocompetent host, after tuberculosis and leprosy. (medscape.com)
  • [ 2 ] Buruli ulcers generally begin as a painless dermal papule or subcutaneous edematous nodule, which, over a period of weeks to months, breaks down to form an extensive necrotic ulcer with undermined edges. (medscape.com)
  • Buruli ulcer can extend to 15% of a person's skin surface and may destroy nerves and blood vessels. (medscape.com)
  • Buruli ulcer was first described by Sir Albert Cook in patients from Buruli County in Uganda, and the causative organism was isolated in 1948 by MacCallum in the Bairnsdale region of Victoria, Australia. (medscape.com)
  • A reemergence of cases led the 1998 World Health Organization (WHO) to reclassify Buruli ulcer as a "neglected emerging infectious disease," which has stimulated ongoing research into diagnosis, pathogenesis, and effective treatment. (medscape.com)
  • Buruli ulcers are traditionally thought to be painless ulcers. (medscape.com)
  • [ 14 ] Another prominent feature of Buruli ulcers is extensive coagulative necrosis caused by mycolactone. (medscape.com)
  • M ulcerans are slow-growing mycobacteria and are the causative agent of Buruli ulcers. (medscape.com)
  • Buruli ulcer is a necrotizing skin disease caused by Myco- cial stigma on patients and their families ( 2,3 ). (cdc.gov)
  • The highest bacterium ulcerans and is usually associated with tropical incidence of Buruli ulcer is found in tropical or subtropical climates and exposure to slow-moving or stagnant water. (cdc.gov)
  • sub-Saharan Africa, but 2 cases have been reported in Mali, We report a case of Buruli ulcer that may have originated in an urban semiarid area of Senegal. (cdc.gov)
  • Buruli ulcer (BU), or Mycobacterium ulcerans disease, is a severe bacterial infection that affects the skin, soft tissues and the bones. (who.int)
  • Buruli ulcer often starts as a painless swelling or nodule on the arms or legs. (who.int)
  • Buruli ulcer, caused by Mycobacterium ulcerans is a chronic debilitating disease that affects mainly affects the skin and sometime bone. (who.int)
  • Buruli ulcer is a chronic debilitating disease caused by Mycobacterium ulcerans . (who.int)
  • At least 33 countries with tropical, subtropical and temperate climates have reported Buruli ulcer in Africa, South America and Western Pacific regions. (who.int)
  • Information gathered from scientific literature shows that Buruli ulcer has been reported in 33 countries in Africa, the Americas, Asia and the Western Pacific. (who.int)
  • The photograph shows dense, perilimbal corneal vascularization, diffuse corneal edema, and a large corneal ulcer with white infiltrate. (merckvetmanual.com)
  • Other types include dog corneal ulcers which can interfere with eyesight and dog mouth ulcers. (dog-health-guide.org)
  • Corneal ulcers may require immediate surgical support to avoid vision loss. (dog-health-guide.org)
  • Canine corneal ulcers that are deep require immediate surgery to avoid vision loss. (dog-health-guide.org)
  • A corneal ulcer is an open sore on the cornea (the clear layer in front of the iris and pupil) that is usually caused by an eye infection. (msdmanuals.com)
  • Corneal ulcers may be caused by infections with bacteria, fungi, viruses, or parasites such as Acanthamoeba (which lives in contaminated water). (msdmanuals.com)
  • A deficiency of vitamin A and protein may lead to the formation of a corneal ulcer. (msdmanuals.com)
  • This kind of irritation can lead to injury and the development of a corneal ulcer. (msdmanuals.com)
  • Corneal ulcers cause redness, pain, usually a feeling like a foreign object is in the eye (foreign body sensation), aching, sensitivity to bright light, and increased tear production. (msdmanuals.com)
  • A corneal ulcer is a corneal epithelial defect with underlying inflammation usually due to invasion by bacteria, fungi, viruses, or Acanthamoeba . (msdmanuals.com)
  • Ulcers caused by Acanthamoeba (also most commonly due to exposure to contaminated water while wearing contact lenses) and fungi (most commonly due to trauma with vegetable material) are indolent but progressive, whereas those caused by Pseudomonas aeruginosa (seen most frequently in contact lens wearers) develop rapidly, causing deep and extensive corneal necrosis. (msdmanuals.com)
  • Ulcers are characterized by corneal epithelial defects with underlying inflammation and necrosis of the corneal stroma. (msdmanuals.com)
  • Corneal ulcers tend to heal with scar tissue, resulting in opacification of the cornea and decreased visual acuity. (msdmanuals.com)
  • A corneal ulcer begins as a corneal epithelial defect that stains with fluorescein and an underlying dull, grayish, circumscribed superficial opacity (representing an infiltrate). (msdmanuals.com)
  • Corneal ulcers due to Acanthamoeba are often intensely painful and may show transient corneal epithelial defects, multiple corneal stromal infiltrates, and, later, a large ring-shaped infiltrate. (msdmanuals.com)
  • ON101 (Fespixon, Oneness Biotech), a first-in-class, macrophage-regulating, wound-healing cream for diabetic foot ulcers has shown benefit over absorbent dressings in a phase 3 trial, with another trial ongoing. (medscape.com)
  • Oneness Biotech has also just started a second phase 3 trial in the United States, with a planned enrollment of 208 patients with diabetic foot ulcers, which will compare ON101 cream versus placebo cream, in addition to standard care, over 20 weeks. (medscape.com)
  • The findings of this study suggest that ON101, a macrophage regulator that behaves differently from moisture-retaining dressings, represents an active-healing alternative for home and primary care of patients with chronic [diabetic foot ulcers]," the researchers conclude. (medscape.com)
  • It is "exciting" to have a new therapy for diabetic foot ulcers, said Cazzell, because they are serious and life-threatening. (medscape.com)
  • However, the number of amputations from chronic diabetic foot ulcers that do not heal is increasing, pointing to a need for better treatment options. (medscape.com)
  • Most (78%) of the diabetic foot ulcers were Wagner grade 2. (medscape.com)
  • Recommendations on various interventions for the prevention of foot ulcers with corresponding rationale. (apta.org)
  • The Diabetes section (prefix DIQ) provides personal interview data on diabetes, use of medications, and symptoms associated with diabetes such as vision problems, foot ulcers and sensations in the extremities. (cdc.gov)
  • NEW YORK (Reuters Health) - A new wound dressing that generates nitric oxide (EDX110) improves healing of diabetic foot ulcers, according to results from the ProNOx1 trial. (medscape.com)
  • The critical factors that delay the healing of diabetic foot ulcers are ischemia and infection," Dr. Michael E. Edmonds from King's College Hospital in London told Reuters Health by email. (medscape.com)
  • Dr. Edmonds and colleagues assessed the safety and efficacy of EDX110 in the treatment of diabetic foot ulcers in their 12-week study of 147 patients. (medscape.com)
  • The study was carried out in a 'real world' population and thus EDX110 is indicated in the management of diabetic foot ulcers, even when mildly infected, and as long as the ankle-brachial pressure index is above 0.5," Dr. Edmonds said. (medscape.com)
  • Regular turning, careful hygiene of common pressure ulcer sites and barrier creams may be used to stop ulcers forming. (clinicaladvisor.com)
  • Nurse cutting away dead tissue from a pressure ulcer on an elderly patient. (clinicaladvisor.com)
  • Nurse putting a clean dressing on a pressure ulcer located on an elderly patient. (clinicaladvisor.com)
  • Close up of a pressure ulcer on the buttock of a patient. (clinicaladvisor.com)
  • A pressure ulcer on the back of a 65-year-old woman. (clinicaladvisor.com)
  • While the severity of these incidents vary from stage I to IV, each pressure ulcer may cost upwards of $120,000 to treat. (alimed.com)
  • Effective pressure ulcer prevention strategies feature nursing staff who rotate patients at regular intervals, but workforce shortages and large patient populations may make this unrealistic. (alimed.com)
  • Trends and racial disparity in primary pressure ulcer hospitalizations outcomes in the US from 2005 to 2014. (bvsalud.org)
  • To examine trends in primary pressure ulcer (PPU) hospitalization mortality , length of hospital stay (LOS), and inflation -adjusted charges (IAC) in the US from 2005 to 2014 by race / ethnicity . (bvsalud.org)
  • The study sample included all hospitalizations with the designated ICD-9-CM code of 707.20-25 ( pressure ulcer ). (bvsalud.org)
  • If you have an actively bleeding ulcer, you'll likely be hospitalized for intensive treatment with endoscopy and IV ulcer medications. (healthline.com)
  • Another common test to look for an ulcer is an endoscopy (pronounced: en-DOSS-kuh-pee). (kidshealth.org)
  • A gastroduodenal endoscopy is the best way to diagnose a dog ulcer. (dog-health-guide.org)
  • Clinical diagnosis hypothesis was either traumatic ulcer or oral squamous cell carcinoma. (bvsalud.org)
  • Lack of TGF-alpha and TGF-beta 1 synthesis by human eosinophils in chronic oral ulcers. (medscape.com)
  • Fungal ulcers, which are more chronic than bacterial ulcers, are densely infiltrated and show occasional multiple discrete islands of infiltrate (satellite lesions) at the periphery. (msdmanuals.com)
  • A 35-year-old handyman has chronic skin ulcers and respiratory irritation. (cdc.gov)
  • Sixty swab specimens obtained from chronic leg ulcer (CLU) patients were cultured aerobically and the antibiotic sensitivity pattern of the recovered organisms determined by the modified Kirby -Bauer disc- diffusion method . (bvsalud.org)
  • Mouth ulcers or canker sores that appear on the tongue usually clear up without treatment. (medicalnewstoday.com)
  • Tongue ulcers are whiteish sores on the tongue. (medicalnewstoday.com)
  • Also called canker sores, a 2019 article notes that these ulcers most often develop on the inside of the lips and cheeks. (medicalnewstoday.com)
  • Ulcers are essentially intestinal sores that won't heal. (horse-canada.com)
  • Contact lenses, injuries, disorders, drugs, and nutritional deficiencies can also cause open sores (ulcers) to form on the cornea. (msdmanuals.com)
  • Those in the duodenum are also called duodenal ulcers. (kidshealth.org)
  • Eosinophilic ulcer of the oral mucosa: a distinct entity or a non-specific reactive pattern? (medscape.com)
  • The eosinophilic ulcer revisited. (medscape.com)
  • Oral eosinophilic ulcer, an Epstein-Barr virus-associated CD30+ lymphoproliferation? (medscape.com)
  • Eosinophilic ulcer of the oral mucosa: report of a child with CD30-negative cells in an infiltration on the lower lip. (medscape.com)
  • A 47-year-old African American woman with an eosinophilic ulcer on the lateral surface of the tongue. (medscape.com)
  • Riga-Fede disease is a form of eosinophilic ulcer that develops in infants and usually occurs on the anterior ventral side of the tongue. (medscape.com)
  • therefore, eosinophilic ulcer also may represent an unusual manifestation of a drug reaction. (medscape.com)
  • However, neither virally altered cells nor viral DNA is identified in biopsy specimens of typical eosinophilic ulcer. (medscape.com)
  • One study demonstrated that, in most eosinophilic ulcer, the synthesis of transforming growth factor-alpha and transforming growth factor-beta is not increased in infiltrating eosinophils. (medscape.com)
  • These findings may help explain the delayed healing that is characteristic of eosinophilic ulcer. (medscape.com)
  • Introduction: Eosinophilic ulcer of the oral mucosa (EUOM) is a lesion manifesting as ulcer with elevated margins. (bvsalud.org)
  • In this article, we discuss tongue ulcers in more detail, including why they occur, their symptoms, and how to treat them. (medicalnewstoday.com)
  • Pressure ulcers often occur in bedridden, elderly patients, especially those who are unconscious. (clinicaladvisor.com)
  • More severe symptoms and complications tend to occur with deeper ulcers. (msdmanuals.com)
  • In addition to protecting against pressure ulcers, these patient positioners also promote access to the surgery site so physicians can complete procedures with fewer complications. (alimed.com)
  • A $75,000 settlement was reached in a civil rights action alleging denial of medical care to a pretrial detainee who died from complications related to a peptic ulcer. (prisonlegalnews.org)
  • ABSTRACT We aimed to study the effect of Ramadan fasting on the occurrence of peptic ulcer disease and its complications in patients presenting to the Accident and Emergency Department at Al-Ain hospital, United Arab Emirates (UAE). (who.int)
  • The deeper the ulcer, the more severe the symptoms and complications. (msdmanuals.com)
  • But despite their efforts, his skin lesions developed into necrotic ulcers and the man's left forearm was amputated 25 days after he first visited the hospital. (newsweek.com)
  • Eosinophilic ulcers are included in this group of nonhealing traumatic ulcers. (medscape.com)
  • Most H. pylori -related ulcers can be cured. (kidshealth.org)
  • With the discovery of the association between H. pylori infection and PUD, appropriate antibiotic regimens can now successfully eradicate gastrointestinal infection with this organism and permanently cure ulcers in a high proportion of patients. (cdc.gov)
  • In 1994, a National Institutes of Health consensus development conference panel concluded that patients with ulcers caused by H. pylori infection require treatment with antimicrobial agents (7). (cdc.gov)
  • You may need surgery if your ulcers don't heal. (medlineplus.gov)
  • Tongue ulcers tend to heal on their own. (medicalnewstoday.com)
  • Any illness that makes it hard for the body to heal (such as serious burns from a fire) also can make someone more likely to get an ulcer. (kidshealth.org)
  • The ulcer may take 8 weeks to heal, but the pain usually goes away after a few days or a week. (kidshealth.org)
  • Traumatic oral ulcers tend to have a sudden onset and usually heal within a few days or weeks, often without clinical intervention. (medscape.com)
  • Infection often leads to ulcers on the arms or legs, which can also destroy skin or soft tissue. (cdc.gov)
  • The most proximal of the 3 ulcers had a diameter of associated with M. ulcerans infection. (cdc.gov)
  • Current standard clinical care for diabetic foot ulcer consists of debridement, off-loading, infection control, and maintaining a moist environment with dressings, Huang and colleagues explain. (medscape.com)
  • Ulcers can be caused by some types of infection, injury, or cancer. (wellspan.org)
  • and 27% (95% CI=25%-29%), that a bacterial infection caused ulcers. (cdc.gov)
  • Bacterial ulcers are most commonly due to contact lens wear and are rarely due to secondary infection from traumatic abrasion or herpes simplex keratitis. (msdmanuals.com)
  • Nitric oxide (NO) plays a crucial role in maintaining the microvascular supply and infection control in the skin, and its absence in diabetes contributes to poor ulcer healing. (medscape.com)
  • Although certain lesions may behave aggressively, overall, these ulcers do not cause significant morbidity. (medscape.com)
  • Some ulcers may have an area of redness around their outer ring, especially if something irritates them. (medicalnewstoday.com)
  • Blepharitis Blepharitis is inflammation of the edges of the eyelids, possibly with thickening scales, crusts, shallow ulcers, or redness and swelling at the edges of the eyelids. (msdmanuals.com)
  • A 37-year-old woman originally presented in May 2003 with a nonhealing, painless ulcer on the plantar surface of her right foot that had been slowly increasing in size for the previous 1.5 years. (japmaonline.org)
  • Diagnosis and treatment will depend on your symptoms and the severity of your ulcer. (healthline.com)
  • More severe ulcers may spread to involve the width of the cornea, may penetrate deeply, or both. (msdmanuals.com)
  • As with many infections, washing your hands well and often is an important part of ulcer prevention. (kidshealth.org)
  • This guideline provides recommendation for the prevention, assessment, and management of pressure ulcers in adults and children in all settings. (apta.org)
  • Drinking a lot of alcohol each day for a period of time can also increase a person's risk of ulcers. (kidshealth.org)
  • Doctors diagnose an ulcer based on the appearance of the person's cornea. (msdmanuals.com)
  • Lethality after gastroduodenal ulcer bleeding]. (arctichealth.org)
  • The retrospective analysis (2006-2010 yy) of treatment of 895 patients with gastroduodenal ulcer bleeding was conducted. (arctichealth.org)
  • Ogbechi et al showed that mycolactone decreased thrombomodulin expression on the surface of human dermal microvascular endothelial cells, thereby impairing the activation of protein C. This study also showed that fibrin deposition is a prominent feature of these ulcers and the tissue necrosis could be caused by fibrin-driven ischemia. (medscape.com)
  • This test is used to look for ulcers, bleeding, and any tissue that looks abnormal. (healthline.com)
  • If the foot ulcer does not respond, growth factors, tissue-engineering products, hyperbaric oxygen, or negative pressure wound therapies may be used. (medscape.com)
  • Peptic ulcer perforation occurred more frequently after Ramadan but the difference was not significant. (who.int)
  • The objective of this study was to investigate whether fasting in the month of Ramadan had any effect on the peptic ulcer frequency and peptic ulcer perforation in Muslim patients presenting to the Accident and Emergency Department of a large hospital in the United Arab Emirates. (who.int)
  • We conducted a retrospective descriptive study of peptic ulcer perforation among patients presenting to the Accident and Emergency Department of Al Ain Hospital in the United Arab Emirates who were then treated at the Departments of Medicine and Surgery. (who.int)
  • When this inherent grazing behaviour is disrupted by changes to diet, environment and other stressors - mainly by the actions of humans - horses often suffer digestive problems, one of the most common being ulcers. (horse-canada.com)
  • In uncomplicated peptic ulcer disease (PUD), the clinical findings are few and nonspecific. (medscape.com)
  • The proportion of ulcers healed at 12 weeks was 40% (30/75) with EDX110 and 26% (19/73) with best clinical practice (P=0.07). (medscape.com)
  • In subgroup analysis, PAR was significantly greater with EDX110 than with best clinical practice among patients whose ulcers had been present for six or fewer months or were at least 1 cm2 at baseline, but not for those whose ulcers had been present for longer or were smaller. (medscape.com)
  • Regression analysis identified the following variables as predictors of peptic ulcer disease: anorexia, pain, hypertension, smoking, epigastric pain, diabetes and family history. (who.int)
  • The mortality from peptic ulcer bleeding has not changed materially in recent years and remains at 7%-10% despite advances in patient management [8]. (who.int)
  • Stress and spicy foods do not cause ulcers, but can make them worse. (medlineplus.gov)
  • Some foods can also aggravate the tongue ulcer, especially those that are spicy or acidic. (medicalnewstoday.com)
  • Ulcers are usually found in the gastrointestinal tract when the lining breaks down due to increased acid production. (dog-health-guide.org)
  • Treatment for gastrointestinal ulcers (GI) involve the use of acid blocking medications and dietary change. (dog-health-guide.org)
  • Most often when we talk about ulcers, we are referring to a small hole or erosion of the gastrointestinal lining. (dog-health-guide.org)
  • Treatment will vary depending on the cause of your ulcer. (healthline.com)
  • Medical treatment for tongue ulcers generally focuses on easing the symptoms while identifying and treating any underlying conditions responsible for the ulcers. (medicalnewstoday.com)
  • Treatment depends on the location of the ulcer. (dog-health-guide.org)
  • Otherwise, treatment will just have to be aimed at the ulcer itself. (dog-health-guide.org)
  • Response to treatment for canine ulcers caused by canine kidney failure, canine liver failure, or due to cancer tends to be poor. (dog-health-guide.org)
  • The response to the treatment depends mostly on the bacterial species, and the ulcer may be particularly refractory to treatment. (msdmanuals.com)
  • If Edixomed prices this appropriately, then EDX110 could become a key part of the treatment pathway of any diabetic foot ulcer, especially when mildly infected. (medscape.com)
  • 12%. They also had to have a Wagner grade 1 or 2 foot ulcer that was 1-25 cm 2 after debridement, had been treated with standard care, and was present for at least 4 weeks. (medscape.com)
  • To diagnose a peptic ulcer, doctors do an exam, ask about symptoms, and take a medical history. (kidshealth.org)
  • The ulcers themselves tend to be white and roundish. (medicalnewstoday.com)
  • Although tongue ulcers tend to clear up on their own, various home remedies may help ease the symptoms during the healing process. (medicalnewstoday.com)
  • The NHS note that people who have several ulcers on the tongue or elsewhere in the mouth may have symptoms of other disorders, such as hand, foot, and mouth disease (HFMD) or oral lichen planus . (medicalnewstoday.com)
  • Some forms of ulcers on the tongue and in the mouth may be signs of oral cancer . (medicalnewstoday.com)
  • Even though discomfort may be mild, ulcers can worsen if they aren't treated. (healthline.com)
  • Ulcers can be shallow or deep and can destroy the skin or the membrane where they develop. (wellspan.org)
  • An ulcer that's not treated can grow larger and deeper. (kidshealth.org)
  • Raised, indurated, nonhealing ulcer on the lateral surface of the tongue. (medscape.com)
  • Get the most up to date information on recognizing and treating equine gastric and colonic ulcers, which are more common than you might think. (horse-canada.com)
  • Pressure ulcers are also know as a decubitus ulcers or a bedsores, is an ulcerated area of skin caused by irritation and continuous pressure on a part of the body. (clinicaladvisor.com)
  • In most patients with eosinophilic ulcers, trauma is the etiologic factor, and the apparent source of irritation is easily identified. (medscape.com)