Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)Dystonic Disorders: Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.Dystonia Musculorum Deformans: A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and face. The hands are often spared, however, sustained axial and limb contractions may lead to a state where the body is grossly contorted. Onset is usually in the first or second decade. Familial patterns of inheritance, primarily autosomal dominant with incomplete penetrance, have been identified. (Adams et al., Principles of Neurology, 6th ed, p1078)Empathy: An individual's objective and insightful awareness of the feelings and behavior of another person. It should be distinguished from sympathy, which is usually nonobjective and noncritical. It includes caring, which is the demonstration of an awareness of and a concern for the good of others. (From Bioethics Thesaurus, 1992)Patient Protection and Affordable Care Act: An Act prohibiting a health plan from establishing lifetime limits or annual limits on the dollar value of benefits for any participant or beneficiary after January 1, 2014. It permits a restricted annual limit for plan years beginning prior to January 1, 2014. It provides that a health plan shall not be prevented from placing annual or lifetime per-beneficiary limits on covered benefits. The Act sets up a competitive health insurance market.Torticollis: A symptom, not a disease, of a twisted neck. In most instances, the head is tipped toward one side and the chin rotated toward the other. The involuntary muscle contractions in the neck region of patients with torticollis can be due to congenital defects, trauma, inflammation, tumors, and neurological or other factors.Health Insurance Exchanges: State-provided health insurance marketplaces established under the PATIENT PROTECTION AND AFFORDABLE CARE ACT.Botulinum Toxins: Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.Hypohidrosis: Abnormally diminished or absent perspiration. Both generalized and segmented (reduced or absent sweating in circumscribed locations) forms of the disease are usually associated with other underlying conditions.Botulinum Toxins, Type A: A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.Neuromuscular Agents: Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS.Anti-Dyskinesia Agents: Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.Democracy: A system of government in which there is free and equal participation by the people in the political decision-making process.Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.Essential Tremor: A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)Neurosurgery: A surgical specialty concerned with the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system.Neurology: A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Gait Disorders, Neurologic: Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.Gait: Manner or style of walking.Affective Symptoms: Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Gait Apraxia: Impaired ambulation not attributed to sensory impairment or motor weakness. FRONTAL LOBE disorders; BASAL GANGLIA DISEASES (e.g., PARKINSONIAN DISORDERS); DEMENTIA, MULTI-INFARCT; ALZHEIMER DISEASE; and other conditions may be associated with gait apraxia.Emotions: Those affective states which can be experienced and have arousing and motivational properties.Health Services Needs and Demand: Health services required by a population or community as well as the health services that the population or community is able and willing to pay for.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Transcranial Magnetic Stimulation: A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.Motor Cortex: Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.Evoked Potentials, Motor: The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.Drug Repositioning: The deliberate and methodical practice of finding new applications for existing drugs.Self-Help Groups: Organizations which provide an environment encouraging social interactions through group activities or individual relationships especially for the purpose of rehabilitating or supporting patients, individuals with common health problems, or the elderly. They include therapeutic social clubs.Psychotherapy, Group: A form of therapy in which two or more patients participate under the guidance of one or more psychotherapists for the purpose of treating emotional disturbances, social maladjustments, and psychotic states.Social Support: Support systems that provide assistance and encouragement to individuals with physical or emotional disabilities in order that they may better cope. Informal social support is usually provided by friends, relatives, or peers, while formal assistance is provided by churches, groups, etc.Post-Concussion Syndrome: The organic and psychogenic disturbances observed after closed head injuries (HEAD INJURIES, CLOSED). Post-concussion syndrome includes subjective physical complaints (i.e. headache, dizziness), cognitive, emotional, and behavioral changes. These disturbances can be chronic, permanent, or late emerging.Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.Brain Concussion: A nonspecific term used to describe transient alterations or loss of consciousness following closed head injuries. The duration of UNCONSCIOUSNESS generally lasts a few seconds, but may persist for several hours. Concussions may be classified as mild, intermediate, and severe. Prolonged periods of unconsciousness (often defined as greater than 6 hours in duration) may be referred to as post-traumatic coma (COMA, POST-HEAD INJURY). (From Rowland, Merritt's Textbook of Neurology, 9th ed, p418)Churg-Strauss Syndrome: Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Torsion Abnormality: An abnormal twisting or rotation of a bodily part or member on its axis.Physicians: Individuals licensed to practice medicine.Nurses: Professionals qualified by graduation from an accredited school of nursing and by passage of a national licensing examination to practice nursing. They provide services to patients requiring assistance in recovering or maintaining their physical or mental health.Coffee: A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.Methotrexate: An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)Checklist: Aid for consistent recording of data such as tasks completed and observations noted.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Glucose Transporter Type 1: A ubiquitously expressed glucose transporter that is important for constitutive, basal GLUCOSE transport. It is predominately expressed in ENDOTHELIAL CELLS and ERYTHROCYTES at the BLOOD-BRAIN BARRIER and is responsible for GLUCOSE entry into the BRAIN.Monosaccharide Transport Proteins: A large group of membrane transport proteins that shuttle MONOSACCHARIDES across CELL MEMBRANES.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Glucose Transporter Type 4: A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of glucose from the BLOOD into target TISSUES. The inactive form of the protein is localized in CYTOPLASMIC VESICLES. In response to INSULIN, it is translocated to the PLASMA MEMBRANE where it facilitates glucose uptake.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Focal hand dystonia[edit]. Focal hand dystonia is a task-related movement disorder associated with occupational activities that ... Two types of gamma activity were found by Snyder & Large: induced gamma activity, and evoked gamma activity. Evoked gamma ... An fMRI study examined five guitarists with focal hand dystonia.[85] The study reproduced task-specific hand dystonia by having ... In one conventional sense, tonality refers to just the major and minor scale types - examples of scales whose elements are ...
Diseases and disorders of the brain, including alogia, aphasias, dysarthria, dystonia and speech processing disorders, where ... This type of mapping plays a key role in enabling children to expand their spoken vocabulary. Masur (1995) found that how often ... of which there are three types: esophageal speech, pharyngeal speech and buccal speech (better known as Donald Duck talk). ...
Cytoplasmic aggregations of wild-type (normal) SOD1 protein are common in sporadic ALS.[35] It is thought that misfolded mutant ... ALS can be classified by the types of motor neurons that are affected. Typical or "classical" ALS involves neurons in the brain ... Motor neurons are more sensitive to excitotoxicity than other types of neurons because they have a lower calcium-buffering ... and because the pathology of SOD1 ALS is thought to be distinct from all other types of ALS; it lacks the abnormal aggregations ...
Cervical dystonia. Insufficient data was available to assess the effectiveness of oral cannabis extract of THC in treating ... Scientists and industry are commercializing various types of breath analyzers to monitor THC in breath.[43] ...
Types[edit]. *Dyssomnias - A broad category of sleep disorders characterized by either hypersomnia or insomnia. The three major ... Research suggests that hypnosis may be helpful in alleviating some types and manifestations of sleep disorders in some patients ...
PSP cases are often split into two subgroups, PSP-Richardson, the classic type, and PSP-Parkinsonism, where a short-term ... Richardson JC, Steele J, Olszewski J (1963). "Supranuclear ophthalmoplegia, pseudobulbar palsy, nuchal dystonia and dementia. a ... nuchal dystonia and dementia". Archives of Neurology. 10 (4): 333-59. doi:10.1001/archneur.1964.00460160003001. PMID 14107684. ... Botox can be used to treat neck dystonia and blepharospasm, but this can aggravate dysphagia.[32] ...
... dystonia, Parkinsonian symptoms, tardive dyskinesia, and depression.[1][7] However, this is not the case with domperidone, ... thereby being free of the extrapyramidal side effects that were associated with drugs of this type.[70] This led to the ...
Paroxysmal nocturnal dystonia or hypnogenic paroxysmal dystonia are other names given to describe FLE symptoms but are simply ... It is the second most common type of epilepsy after temporal lobe epilepsy (TLE), and is related to the temporal form by the ... In 23 states, the restrictions and seizure free periods vary depending on the type of epilepsy and the individual case and in ... Tonic posture and clonic movements are common symptoms among most of the areas of the frontal lobe, therefore the type of ...
Less typical side effects are those of the cardiovascular system, such as high blood pressure, various types of arrhythmia, and ... Dystonia and cognitive impairment have also been reported as a side effect.[29] ...
The type of Leigh syndrome found at a much higher rate in the Saguenay-Lac-Saint-Jean region of Quebec is caused by a mutation ... Dystonia, nystagmus, and problems with the autonomic nervous system suggest damage to the basal ganglia and brain stem ... "Leigh Syndrome, French Canadian type". Online Mendelian Inheritance in Man. Johns Hopkins University. 1 December 2011. ... French Canadian Leigh syndrome has similar symptoms to other types of Leigh syndrome. The age of onset is, on average, 5 months ...
Additionally, there is a mixed type that shows a combination of features of the other types. These classifications reflect the ... High muscle tone can either be due to spasticity or dystonia.[13] ... is by far the most common type of overall cerebral palsy, occurring in upwards of 70% of all cases.[75] People with this type ... Rh blood type incompatibility can cause the mother's immune system to attack the baby's red blood cells.[1] ...
Types of blink[edit]. There are three types of blink. Spontaneous blink[edit]. Spontaneous blinking which is done without ... "Spontaneous and reflex activity of facial muscles in dystonia, Parkinson's disease, and in normal subjects". Journal of ... This type of blinking is conducted in the pre-motor brain stem and happens without conscious effort, like breathing and ...
Types[edit]. Demyelinating diseases can be divided in those affecting the central nervous system (CNS) and those affecting the ... "A Tale of Treatable Infantile Neuroregression and Diagnostic Dilemma with Glutaric Aciduria Type I." J Pediatr Neurosci. 12 (4 ...
Most SPS patients have the DQB1* 0201 allele.[2] This allele is also associated with type 1 diabetes.[28] ... A variety of conditions have similar symptoms to SPS, including myelopathies, dystonias, spinocerebellar degenerations, primary ... About 35 percent of SPS patients have type I diabetes.[2] ...
... leading to dystonias.[138] Stem cell transplants are a recent research target, because stem cells are easy to manipulate and ... another type of glial cell) in the substantia nigra.[53] ...
About half of patients have associated dystonia, including cervical dystonia, writer's cramp, spasmodic dysphonia, and cranial ... This type of tremor is often referred to as "kinetic tremor". Essential tremor has been known as "benign essential tremor", but ... Other types of tremor may also occur, including postural tremor of the outstretched arms, intention tremor of the arms and rest ... Samotus O, Kumar N, Rizek P, Jog M (January 2018). "Botulinum Toxin Type A Injections as Monotherapy for Upper Limb Essential ...
Both biopsy samples and various types of brain scans have shown an increased water content of the brain tissue. It remains ... it is possible that this procedure will become the first-line type of shunt treatment.[5] ...
Kachi T (December 2001). "[Medical treatment of dystonia]". Rinsho Shinkeigaku (in Japanese). 41 (12): 1181-2. PMID 12235832.. ... Benzodiazepines are positive allosteric modulators of the GABA type A receptors (GABAA). The GABAA receptors are ligand-gated ... Mezaki T, Hayashi A, Nakase H, Hasegawa K (September 2005). "[Therapy of dystonia in Japan]". Rinsho Shinkeigaku (in Japanese ... Pérez Trullen JM, Modrego Pardo PJ, Vázquez André M, López Lozano JJ (1992). "Bromazepam-induced dystonia". Biomedicine & ...
Mental retardation X linked Brunner type. *Mental retardation X linked dysmorphism. *Mental retardation X linked dystonia ...
index of Dissonance for any musical scales in LucyTuning and meantone-type tunings ...
"Reduced genital sensitivity in female patients with multiple system atrophy of parkinsonian type". Mov. Disord. 18 (4): 430-2. ... that mesenchymal stem cell therapy could delay the progression of neurological deficits in patients with MSA-cerebellar type, ...
... called Huntington's disease-like syndrome types 1, 2 and 3; inherited prion disease, the spinocerebellar ataxias type 1, 3 and ... Treatment depends on the type of chorea and the associated disease. Although there are many drugs that can control it, no cure ...
... class-title-folate-and-vitamin-b-span-class-sub-12-span-friendly-or-enemy-nutrients-for-the-elderly-a-href-fn001-ref-type-fn-a- ...
embryonic camera-type eye morphogenesis. • social organism behavior. • cellular response to manganese ion. • response to ether ... Clinical features include dystonia that is minimally or nonresponsive to levodopa, extrapyramidal symptoms, ptosis, miosis, and ... Knappskog PM, Flatmark T, Mallet J, Lüdecke B, Bartholomé K (Jul 1995). "Recessively inherited L-DOPA-responsive dystonia ... alternative splicing from a single gene accounts for generation of four mRNA types". Journal of Biochemistry. 103 (6): 907-12. ...
The different case definitions used to research the illness influence the types of patients selected for studies,[76] and ... The Cochrane review also noted that research was inconclusive as to which, if any, type of exercise therapy was superior, and ... The report also noted that a focus on exercise programs had discouraged patient participation in other types of physical ...
A combination of blepharospasm and oromandibular dystonia. Early-onset torsion dystonia: The most severe type of dystonia, it ... The type of surgery performed is specific to the type of dystonia that the patient has[citation needed]. The disease is more ... Cervical dystonia (spasmodic torticollis): A type of dystonia that affects the head, neck and spine. It can create problems by ... Blepharospasm: This type of dystonia causes involuntary contraction of the eyelids. The main concern for this dystonia is that ...
... dystonia affects an estimated 500,000 people in North America. At least 15 different types of dystonia are considered to be ... DYT6 dystonia). "Another mutation in a German family with this type of dystonia was also identified, suggesting that THAP1 ... This is the second gene identified for this type of dystonia. The study was published online on February 1st in Nature Genetics ... Home , Service Areas , Neurology , News , Gene Mutations Identified As Cause of Primary Torsion Dystonia ...
Researchers have identified a gene that causes adult-onset primary cervical dystonia, an often-painful condition in which ... Single blood test screens for eight cancer types. Jan 18, 2018 0 ... "Cervical dystonia is the most common focal, fixed, adult-onset ... Researchers ID gene behind primary cervical dystonia, a neck-twisting disorder. March 5, 2012, Mayo Clinic Researchers have ... Uitti went to visit their sister, she had the same kind of dystonia. Eventually, seven people in the extended family were ...
Spasmodic torticollis is a form of dystonia. There are various types of dystonia, identified by where they occur in your body ... Dystonias involving only one limb or body part are referred to as focal. Spasmodic torticollis is the most common type of focal ... dystonia, Spasmodic torticollis can occur at any time from birth to adulthood, but most often it occurs in young adults. Its ... also called torticollis or cervical dystonia, is a painful condition in which your neck muscles contract involuntarily, causing ...
Once the more serious causes of torticollis are ruled out (such as a severe type of infection like a retropharyngeal abscess or ... If a patient has a family history of torticollis, they may have a more serious form of torticollis called cervical dystonia. ... bacterial meningitis, fracture, neoplasm, cervical dystonia, etc.), conservative care can proceed. ...
This study compared the cost-effectiveness of treating post-stroke upper limb spasticity with botulinum toxin type A plus an ... The base case incremental cost-effectiveness ratio (ICER) of botulinum toxin type A plus therapy was £93,500 per QALY gained. ... The probability of botulinum toxin type A plus therapy being cost-effective at the England and Wales cost-effectiveness ... and the probability of botulinum toxin type A plus therapy being cost-effective at the threshold value did not exceed 0.39, ...
Dystonia is characterized by involuntary movements and extended muscle contractions. Here, learn about the symptoms and the ... Dystonia refers to a range of movement disorders that affect the brain and nerves, but not cognitive abilities such as memory. ... Some types of dystonia are linked to faulty genes.. Causes of secondary dystonia. This type of dystonia is caused by a ... Types. Dystonia can be classified according to its underlying cause:. Primary dystonia - not related to another condition. No ...
Dystonia is characterized by involuntary movements and extended muscle contractions. Here, learn about the symptoms and the ... Dystonia refers to a range of movement disorders that affect the brain and nerves, but not cognitive abilities such as memory. ... Some types of dystonia are linked to faulty genes.. Causes of secondary dystonia. This type of dystonia is caused by a ... What is dystonia?. Share on Pinterest. Dystonias are a group of neurological conditions.. Dystonia is a neurological condition ...
About Dystonia*Types of Dystonia*Dopa-responsive dystonia. *Eye Dystonia (Blepharospasm)*Why eye dystonia is often misdiagnosed ... About Dystonia*Types of Dystonia*Dopa-responsive dystonia. *Eye Dystonia (Blepharospasm)*Why eye dystonia is often misdiagnosed ... Type of Dystonia. Part of the body affected. Symptoms. Primary generalised dystonia. Throughout the body, particularly the ... Dystonia. All or part of the body. • Episodes during which dystonia affects the body - often hemidystonia or generalied. • ...
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... sometimes referred to as dystonias, which is a neurological disorder. Physician developed and monitored. ... Dystonia Types. Types of dystonia are classified in three ways: Dystonias can be classified according to the part of the body ... Overview of Dystonia. Dystonia (sometimes referred to in the plural, dystonias, because of the many different types) is a ... Generalized dystonia involves most or all of the body.. *Focal dystonia is found in one specific area of the body, such as a ...
... weakens voluntary muscle strength and is an effective therapy for focal dystonia, including cervical dystonia (CD) and benign ... Botulinum toxin type A therapy for cervical dystonia. Cochrane Database Syst Rev 2005; (1): CD003633Google Scholar ... A new botulinum toxin type A free of complexing proteins for treatment of cervical dystonia. Neurology 2005; 64: 1949-51PubMed ... Botulinum neurotoxin type A (BTX-A) weakens voluntary muscle strength and is an effective therapy for focal dystonia, including ...
Types Five major types of Dystonia. Focal dystonia. - affecting muscles around the eyes, in the neck, in the throat or in one ... Laryngeal Dystonia (Spasmodic Dysphonia): affects the muscles of the larynx and vocal cords. The Adductor type causes the voice ... Multifocal dystonia. - affecting many different parts of the body.. Generalised dystonia. - affects most parts of the body, ... Common forms of Focal Dystonia. Cervical Dystonia (Spasmodic Torticollis): affects the neck muscles and causes the head to ...
Botulinum toxin type A (BOTOX®) Botulinum toxin type A (Dysport®) Arm/Group Description Botulinum toxin type A (BOTOX®) ... Botulinum toxin type A (BOTOX®) Botulinum toxin type A (Dysport®) Arm/Group Description Botulinum toxin type A (BOTOX®) ... Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia. The safety and ... Botulinum toxin type A (Dysport®) Total of all reporting groups Arm/Group Description Botulinum toxin type A (BOTOX®) Botulinum ...
Comparison of Efficacy and Safety of Two Different Types of Botulinum Toxin Type A in Moderate to Severe Cervical Dystonia. The ... Study Type: Interventional. Study Design: Allocation: Randomized; Intervention Model: Parallel Assignment; Masking: Triple ( ... Physician Assessment of Cervical Dystonia Severity at Week 4 [ Time Frame: Baseline, Week 4 ]. ...
... cervical dystonia, cranial dystonia, or writers cramp); segmental dystonia (cranio-cervical dystonia or neck/arm dystonia), ... Two hundred and sixty-seven patients had focal dystonia (207 patients with cervical dystonia, 32 patients with cranial dystonia ... All types of tremor were found to be more frequent in patients with multifocal and segmental dystonia than in patients with ... has disclosed associated dystonia, including cervical dystonia, writers cramp, spasmodic dysphonia, and cranial dystonia, in ...
... facilities Comparative analysis Botulinum toxin Dosage and administration Patient outcomes Botulinum toxins Clinics Dystonia ... Clinical characteristics and response to long-term botulinum toxin type A therapy in patients with cervical dystonia at a ... The percentage of both types of focal dystonia (blepharospasm and hand/arm dystonia) was 10% in the Jankovic et al. study (1). ... BoNT-A: Botulinum toxin type A, CD: Cervical dystonia, U: Unit. Table 4. The comparison of BoNT-A treatment data of the first ...
People with certain types of cervical dystonia, in particular the types that make the head turn mostly backward or forward, ... Treatment with botulinum toxin type A for people with involuntary posturing of the head, or cervical dystonia. The review ... Cervical dystonia is the most common form of focal dystonia and is a highly disabling movement disorder characterised by ... A comparison of botulinum toxin type A versus botulinum toxin type B for involuntary positioning of the head, or cervical ...
Niemann-Pick type C (NP-C) is a rare autosomal recessive progressive neurodegenerative disorder caused by mutations in the NP-C ... Dystonia was also present in five patients, with only in one of them dystonia being the presenting symptom. In two patients ... Ataxia, dystonia and myoclonus in adult patients with Niemann-Pick type C. ... 1) suffered from dystonia of face, trunk and extremities and in another patient (nr. 4) facial and cervical dystonia were ...
... by the University of Pittsburgh Department of Pathology in which a 24-year-old female has progressive lower extremity dystonia ... Type:. Other. Description:. This is a neuropathology case study presented by the University of Pittsburgh Department of ... Pathology Case Study: Progressive Lower Extremity Dystonia, Dysarthia, Dysphagia and Mental Impairment. Website Address:https ... www.curriki.org/oer/Pathology-Case-Study-Progressive-Lower-Extremity-Dystonia-Dysarthia-Dysphagia-and-Mental-Impairment-168860 ...
Despite an incomplete understanding of the neurological mechanisms underlying dystonia, relief of dystonic posturing and ... Introduction Dystonia is a disorder characterized by involuntary sustained muscle contractions resulting in twisting and ... the most frequently occurring types of which include cervical dystonia, blepharospasm, hand dystonia, oromandibular dystonia, ... Cervical dystonia. See the list below:. * Cervical dystonia (CD) is the most common form of focal dystonia and is characterized ...
... or epigenetic factors influencing the development of alternating hemiplegia of childhood or rapid-onset dystonia parkinsonism. ... Publication types * Case Reports * Research Support, Non-U.S. Govt MeSH terms * Adult ... Identical ATP1A3 mutation causes alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism phenotypes Pediatr ... Results: Gene sequencing revealed an identical ATP1A3 mutation as in three typical adult-onset rapid-onset dystonia ...
Pilot study on trihexyphenidyl in the treatment of dystonia in children with cerebral palsy. Download Prime PubMed App to ... Rating scales for dystonia in cerebral palsy: reliability and validity.. *Can spasticity and dystonia be independently measured ... The primary outcome measure was the Barry-Albright Dystonia scale for global assessment of dystonia. Secondary measures ... The primary outcome measure was the Barry-Albright Dystonia scale for global assessment of dystonia. Secondary measures ...
Publication types, MeSH terms, Substance. Publication types. *Historical Article. *Research Support, Non-U.S. Govt ... While Hermann Oppenheim probably described the first cases of genetic (DYT1) dystonia in 1911, the modern history of dystonia ... Confirmed genes for isolated dystonias include TOR1A/DYT1; THAP1/DYT6; GNAL/DYT25. In the combined forms, dystonia is ... Genetics in dystonia.. Klein C1.. Author information. 1. Institute of Neurogenetics, University of Lübeck, Lübeck, Germany. ...
A recent client came to me with a condition the medical community says is "incurable". She has dystonia. Her neck and shoulder ...
  • This specific type of dystonia is frequently found in children, with symptoms starting around the ages of 11 or 12. (wikipedia.org)
  • The complications surrounding this form of dystonia are speech related and can cause symptoms such as speech that wavers, speech that sounds like a whisper, or speech that is hesitant. (wikipedia.org)
  • Based on the families we identified, dystonia due to DYT6 is similar to DYT1 in that it starts in childhood and can affect many muscles but, unlike DYT1, people who have the DYT6 mutation are more likely to have problems in the lower face, jaw and vocal cords. (mountsinai.org)
  • Another mutation in a German family with this type of dystonia was also identified, suggesting that THAP1 mutations may cause dystonia in other ancestry groups," said study co-author Laurie Ozelius, PhD, Bachmann Strauss Professor and Associate Professor of Genetics and Genomic Sciences and Neurology at Mount Sinai School of Medicine. (mountsinai.org)
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