Two offspring from the same PREGNANCY. They are from two OVA, fertilized at about the same time by two SPERMATOZOA. Such twins are genetically distinct and can be of different sexes.
Two off-spring from the same PREGNANCY. They are from a single fertilized OVUM that split into two EMBRYOS. Such twins are usually genetically identical and of the same sex.
Disorders affecting TWINS, one or both, at any age.
Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).
Conjoined twins are a rare type of monozygotic twinning where genetically identical individuals form a single organism with varying degrees of physical connection and shared anatomy due to incomplete division during embryonic development.
Methods of detecting genetic etiology in human traits. The basic premise of twin studies is that monozygotic twins, being formed by the division of a single fertilized ovum, carry identical genes, while dizygotic twins, being formed by the fertilization of two ova by two different spermatozoa, are genetically no more similar than two siblings born after separate pregnancies. (Last, J.M., A Dictionary of Epidemiology, 2d ed)
The condition of carrying TWINS simultaneously.
The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
Three individuals derived from three FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
The condition of carrying two or more FETUSES simultaneously.
The division of a ZYGOTE into two parts, each of which is capable of further development.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
The combined effects of genotypes and environmental factors together on phenotypic characteristics.
The experimental study of the relationship between the genotype of an organism and its behavior. The scope includes the effects of genes on simple sensory processes to complex organization of the nervous system.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
The different ways GENES and their ALLELES interact during the transmission of genetic traits that effect the outcome of GENE EXPRESSION.
Analysis of the level of specific BIOMARKERS in a pregnant woman's sera to identify those at risk for PREGNANCY COMPLICATIONS or BIRTH DEFECTS.
Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)
I'm sorry for any confusion, but "Denmark" is not a medical term and does not have a medical definition. It is a country located in northern Europe. If you have any questions related to medicine or health, I would be happy to try to help answer them.
The transmission of traits encoded in GENES from parent to offspring.
A characteristic showing quantitative inheritance such as SKIN PIGMENTATION in humans. (From A Dictionary of Genetics, 4th ed)
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
An infant during the first month after birth.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from different individuals. This contrasts with MOSAICISM in which the different cell populations are derived from a single individual.
The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.
I'm sorry for any confusion, but "Sweden" is not a medical term and does not have a medical definition. It is a country located in Northern Europe. If you have any questions related to medical topics or definitions, I would be happy to try to help answer them!
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
Persons or animals having at least one parent in common. (American College Dictionary, 3d ed)
I'm sorry for any confusion, but "Finland" is not a medical term and does not have a medical definition. It is a country located in Northern Europe, known officially as the Republic of Finland. If you have any questions related to medical topics or definitions, I would be happy to help with those!
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The age of the mother in PREGNANCY.

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. (1/905)

OBJECTIVE: Degenerative intervertebral disc disease is common; however, the importance of genetic factors is unknown. This study sought to determine the extent of genetic influences on disc degeneration by classic twin study methods using magnetic resonance imaging (MRI). METHODS: We compared MRI features of degenerative disc disease in the cervical and lumbar spine of 172 monozygotic and 154 dizygotic twins (mean age 51.7 and 54.4, respectively) who were unselected for back pain or disc disease. An overall score for disc degeneration was calculated as the sum of the grades for disc height, bulge, osteophytosis, and signal intensity at each level. A "severe disease" score (excluding minor grades) and an "extent of disease" score (number of levels affected) were also calculated. RESULTS: For the overall score, heritability was 74% (95% confidence interval [95% CI] 64-81%) at the lumbar spine and 73% (95% CI 64-80%) at the cervical spine. For "severe disease," heritability was 64% and 79% at the lumbar and cervical spine, respectively, and for "extent of disease," heritability was 63% and 63%, respectively. These results were adjusted for age, weight, height, smoking, occupational manual work, and exercise. Examination of individual features revealed that disc height and bulge were highly heritable at both sites, and osteophytes were heritable in the lumbar spine. CONCLUSION: These results suggest an important genetic influence on variation in intervertebral disc degeneration. However, variation in disc signal is largely influenced by environmental factors shared by twins. The use of MRI scans to determine the phenotype in family and population studies should allow a better understanding of disease mechanisms and the identification of the genes involved.  (+info)

Marmoset species variation in the humoral antibody response: in vivo and in vitro studies. (2/905)

A comparison of the in vivo and in vitro antibody response capabilities of two marmoset species, Saguinus fuscicollis and Saguinus oedipus oedipus, revealed the former to be superior in elaborating humoral antibody. In vivo challenges with Escherichia coli lipopolysaccharide (LPS) and Salmonella typhi flagella consistently yielded higher antibody titres in S. fuscicollis; indeed, with LPS antigen, multiple inoculations of S.o. oedipus marmosets led ultimately to a decrease in antibody formation, in contrast to the anamnestic response of S. fuscicollis. This species differential in immune competence was also suggested in the in vitro stimulation of peripheral blood leucocytes (PBL) and spleen cells with sheep red blood cells (RBC). None of 55 S.o. oedipus PBL cultures and 49 of 89 (55%) S. fuscicollis cultures responded to the test antigen. A similar differential in response to sheep RBC was noted with the spleen cells of each species, although this report contrasts the antibody-forming potential of two marmoset species, a comparison of the immunological response profile of marmosets to those of other laboratory animals challenged with similar antigens suggests these primates may be relatively incompetent. The possible relationship between the haemopoietic chimerism of marmosets and a diminished immune competence is discussed.  (+info)

Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study. (3/905)

OBJECTIVE: To test the hypothesis that non-diabetic dizygotic and monozygotic twin siblings of patients with type 1 diabetes have a similar high prevalence of islet cell autoantibodies, thus suggesting that islet cell autoimmunity is mainly environmentally determined. DESIGN: Prospective twin study. SETTING: Two specialist centres for diabetes in the United States. PARTICIPANTS: Non-diabetic monozygotic twin (n=53), dizygotic twin (n=30), and non-twin (n=149) siblings of patients with type 1 diabetes; 101 controls. MAIN OUTCOME MEASURES: Analysis of progression to diabetes and expression of anti-islet autoantibodies. RESULTS: Monozygotic twin siblings had a higher risk of progression to diabetes (12/53) than dizygotic twin siblings (0/30; P<0.005). At the last follow up 22 (41.5%) monozygotic twin siblings expressed autoantibodies compared with 6 (20%) dizygotic twin siblings (P<0.05), 16 (10.7%) non-twin siblings (P<0.0001), and 6 (5.9%) controls (P<0.0001). Monozygotic twin siblings expressed multiple (>/=2) antibodies more often than dizygotic twin siblings (10/38 v 1/23; P<0.05). By life table analysis the probability of developing positive autoantibodies was higher among the monozygotic twin siblings bearing the diabetes associated HLA DQ8/DQ2 genotype than in those without this genotype (64.2% (95% confidence interval 32.5% to 96%) v 23.5% (7% to 40%) at 10 years of discordance; P<0.05). CONCLUSION: Monozygotic and dizygotic twins differ in progression to diabetes and expression of islet cell autoantibodies. Dizygotic twin siblings are similar to non-twin siblings. These two observations suggest that genetic factors play an important part in determination of islet cell autoimmunity, thus rejecting the hypothesis. In addition, there is a high penetrance of islet cell autoimmunity in DQ8/DQ2 monozygotic twin siblings.  (+info)

Breast cancer risk in monozygotic and dizygotic female twins: a 20-year population-based cohort study in Finland from 1976 to 1995. (4/905)

This population-based study investigated the occurrence of breast cancer over a 20-year period in a cohort of monozygotic (MZ) and dizygotic (DZ) twins in Finland. Altogether, 13,176 female twins of known zygosity who were living in Finland at the end of 1975 were identified from the Finnish Twin Cohort Study and followed-up for cancer through the Finnish Cancer Registry for the years 1976-1995. Standardized incidence ratios (SIRs) were calculated, based on national cancer incidence rates. The relative risk of breast cancer for MZ twins compared to DZ twins was decreased [SIR(MZ)/SIR(DZ) ratio = 0.78; 95% confidence interval (CI), 0.58-1.0]; the decreased risk for MZ twins (SIR = 0.76; 95% CI, 0.58-1.0) accounted for this result, whereas the risk for DZ twins did not differ from the general population risk (SIR = 0.98; 95% CI, 0.84-1.1). There was no risk decrease among MZ twins in other cancers related to reproductive behavior; i.e., number of children and age at first birth seem not to explain the decreased risk of breast cancer. Our results, which are in line with earlier studies on the same topic, suggest that prenatal influences or postnatal behavioral factors may protect MZ female twins from breast cancer.  (+info)

Genetic effects on weight change and food intake in Swedish adult twins. (5/905)

BACKGROUND: Obesity is influenced by genetic and environmental factors. Additionally, synergistic effects of genes and environments may be important in the development of obesity. OBJECTIVE: The aim of this study was to test for genetic effects on food consumption frequency, food preferences, and their interaction with subsequent weight gain. DESIGN: Complete data on the frequencies of consumption of 11 foods typical of the Swedish diet were available for 98 monozygotic and 176 dizygotic twin pairs aged 25-59 y who are part of the Swedish Twin Registry. The data were collected in 1973 as part of a questionnaire study. Body mass index was measured in 1973 and again in 1984. RESULTS: There was some evidence that genetic effects influenced the frequency of intake of some foods. Similarity among monozygotic twins exceeded that among dizygotic twins for intake of flour and grain products and fruit in men and women, intake of milk in men, and intake of vegetables and rice in women, suggesting that genes influence preferences for these foods. Analyses conducted for twins reared together and apart also suggested greater monozygotic than dizygotic correlations, but cross-twin, cross-trait correlations were all insignificant, suggesting that the genes that affect consumption frequencies are not responsible for mediating the relation between the frequency of intake and weight change. CONCLUSIONS: Genetic effects and the frequency of intake are independently related to change in body mass index. However, there was no suggestion of differential genetic effects on weight gain that were dependent on the consumption frequency of the foods studied.  (+info)

Fetal and infant death in mono- and dizygotic twins in England and Wales 1982-91. (6/905)

AIM: To quantify the level of risk for stillbirth and infant death in singleton compared with twin pregnancies, using national data; to determine the independent effects of zygosity, sex, and birthweight on these risks in twin pregnancies. METHODS: A retrospective national study was carried out of all singleton and twin birth and death registrations in England and Wales 1982-91, according to sex and birthweight group. Weinberg's rule was applied to the twin pairs to differentiate mono- from dizygotic twins. Relative risks for mono- compared with dizygous twins for both twins being stillbirths and for one of the pair being a stillbirth were determined. For twins where one was stillborn and the other live born, the relative risk of neonatal and infant mortality in the surviving co-twin was determined. RESULTS: There were 6 563 834 registered singletons and 70772 registered twin pairs for the period under study. Monozygotic twins had a relative risk of: 18.91 (95% CI 12.48-28.64) for both twins being stillborn; 1.63 (95% CI 1.48-1.79) for one twin being a stillbirth; and 2.26 (95% CI 1.45-3.52) for the live born co-twin dying as a neonate. When both twins were live born and among singletons, the odds ratio for neonatal mortality of being male was 1.41 (95% CI 1.37-1.45) and there was a highly significant negative association with birthweight. After adjusting for birthweight group and sex, twins had a reduced neonatal mortality compared with singletons: odds ratio 0.91 (95% CI 0.85-0.96). CONCLUSIONS: Fetal death in one of monozygotic twins has serious implications for survival of the co-twin. Monochorionicity is probably the essential feature of the increased risk to the co-twin. It is imperative that all fetal deaths in multiple pregnancies are recorded and chorionicity determined if parents are to be adequately counselled.  (+info)

QT interval is linked to 2 long-QT syndrome loci in normal subjects. (7/905)

BACKGROUND: The rate-corrected QT interval (QTc) is heritable, and the discovery of quantitative trait loci that influence the QTc would be an important step in identifying the genes responsible for life-threatening arrhythmias in the general population. We studied 66 pairs of unselected normal dizygotic (DZ) twin subjects and their parents in a sib-pair analysis. We tested for linkage of gene loci harboring genes known to cause the long-QT syndrome (LQT) to the quantitative trait QTc. METHODS AND RESULTS: We found genetic variance on QRS duration, QRS axis, T-wave axis, and QTc. Women had a longer QTc than men. Microsatellite markers were tested in the vicinity of the gene loci for the 5 known LQT genes. We found significant linkage of QTc with the loci for LQT1 on chromosome 11 and LQT4 on chromosome 4 but not to LQT2, LQT3, or LQT5. We also found linkage of the QRS axis with LQT2 and LQT3. CONCLUSIONS: We suggest that these quantitative trait loci may represent the presence of variations in LQT genes that could be important to the risk for rhythm disturbances in the general population.  (+info)

Does zygosity influence the metabolic profile of twins? A population based cross sectional study. (8/905)

OBJECTIVE: To study the influence of zygosity on the metabolic variables involved in the pathophysiology of type 2 diabetes. DESIGN: Population based cross sectional study. SETTING: Odense University Hospital, Denmark. PARTICIPANTS: 125 monozygotic twin pairs and 178 dizygotic twin pairs of the same sex born between 1921 and 1940. MAIN OUTCOME MEASURES: Clinical characteristics of monozygotic and dizygotic twins with or without a family history of type 2 diabetes. RESULTS: Absolute prevalences of type 2 diabetes and impaired glucose tolerance according to the World Health Organisation criteria were similar in both the monozygotic and the dizygotic twins as were measurements of height, weight, body mass index, waist to hip ratio, and fasting plasma glucose and insulin concentrations. During the oral glucose tolerance test, monozygotic twins had a higher incremental plasma insulin area under the curve than dizygotic twins (10.05 (SD 0.68) v 9.89 (0.72) pmol/lxminutes, P<0.01) indicating insulin resistance. In twins with normal glucose tolerance and without first degree relatives or co-twins with type 2 diabetes or impaired glucose tolerance, both the glucose and insulin areas under the curve were higher among monozygotic twins (glucose 214.4 (88.3) v 189.8 (78.4) mmol/lxminutes, P<0.05; insulin 20 040 (14 865-32 554) v 17 625 (12 330-23 640) pmol/lxminutes, P=0.08). CONCLUSION: Zygosity influences both plasma glucose and plasma insulin concentrations during an oral glucose tolerance test. This supports an intrauterine influence on glucose homeostasis and perhaps on insulin resistance in humans.  (+info)

Dizygotic twins, also known as fraternal twins, are a result of two separate sperm fertilizing two separate eggs during conception. These twins share about 50% of their genes, similar to any non-twin siblings. They may be of the same sex or different sexes and can vary in appearance, personality, and interests. Dizygotic twins typically do not share a placenta or a sac in the womb, but they may share a chorion (outer fetal membrane).

Monozygotic twins, also known as identical twins, are derived from a single fertilized egg (ovum) that splits and develops into two separate embryos. This results in the formation of genetically identical individuals who share the same genetic material, with the exception of potential mutations that may occur after the split. Monozygotic twins have the same sex, blood type, and other genetic traits. They are a unique pair of siblings, sharing an extraordinary degree of resemblance in physical characteristics, abilities, and behaviors.

'Diseases in Twins' is a field of study that focuses on the similarities and differences in the occurrence, development, and outcomes of diseases among twins. This research can provide valuable insights into the genetic and environmental factors that contribute to various medical conditions.

Twins can be classified into two types: monozygotic (identical) and dizygotic (fraternal). Monozygotic twins share 100% of their genes, while dizygotic twins share about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood of both twins having the same disease) between monozygotic and dizygotic twins, researchers can estimate the heritability of a particular disease.

Studying diseases in twins also helps understand the role of environmental factors. When both twins develop the same disease, but they are discordant for certain risk factors (e.g., one twin smokes and the other does not), it suggests that the disease may have a stronger genetic component. On the other hand, when both twins share similar risk factors and develop the disease, it implies that environmental factors play a significant role.

Diseases in Twins research has contributed to our understanding of various medical conditions, including infectious diseases, cancer, mental health disorders, and developmental disorders. This knowledge can lead to better prevention strategies, early detection methods, and more targeted treatments for these diseases.

In the field of medicine, twins are defined as two offspring produced by the same pregnancy. They can be either monozygotic (identical) or dizygotic (fraternal). Monozygotic twins develop from a single fertilized egg that splits into two separate embryos, resulting in individuals who share identical genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to siblings who share about 50% of their genetic material, similar to non-twin siblings.

Conjoined twins, also known as Siamese twins, are a rare type of monozygotic (identical) twins who are born physically connected to each other. They develop from a single fertilized egg that fails to fully separate, resulting in various degrees of fusion between their bodies. The point of connection and the extent of sharing body parts can vary greatly between sets of conjoined twins. Some may be connected at the chest, abdomen, or hips, while others may share vital organs such as the heart or brain. Treatment options depend on the type of conjunction and whether separation is possible without causing harm to either twin. Conjoined twins occur in about 1 in every 200,000 live births.

"Twin studies" is a type of research design used in medical and scientific research, particularly in the field of genetics. This method involves comparing similarities and differences between monozygotic (identical) twins and dizygotic (fraternal) twins to estimate the heritability of certain traits or conditions.

Monozygotic twins share 100% of their genetic material, while dizygotic twins share only about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood that both twins in a pair will have the same trait or condition) between monozygotic and dizygotic twins, researchers can estimate the proportion of variation in a trait that is due to genetic factors (heritability).

Twin studies can provide valuable insights into the genetic and environmental contributions to various traits and conditions, including physical characteristics, cognitive abilities, personality traits, and susceptibility to diseases. However, it's important to note that twin studies have limitations, such as the potential for environmental influences to be confounded with genetic factors, and the assumption that monozygotic twins share all of their genetic material, which is not always the case due to rare genetic events like mutations during development.

Twin pregnancy refers to a type of multiple pregnancy where a woman is carrying two fetuses simultaneously. There are two types of twin pregnancies: monozygotic (identical) and dizygotic (fraternal). Monoygotic twins occur when a single fertilized egg (zygote) splits and develops into two separate embryos, resulting in identical twins who share the same genetic material. Dizygotic twins, on the other hand, result from the fertilization of two separate eggs by two different sperm cells, leading to non-identical twins who have their own unique genetic material.

Twin pregnancies are associated with higher risks of complications compared to singleton pregnancies, including preterm labor, low birth weight, gestational diabetes, and preeclampsia. Close monitoring by healthcare providers is essential to ensure the best possible outcomes for both the mother and the twins.

The term "environment" in a medical context generally refers to the external conditions and surroundings that can have an impact on living organisms, including humans. This includes both physical factors such as air quality, water supply, soil composition, temperature, and radiation, as well as biological factors such as the presence of microorganisms, plants, and animals.

In public health and epidemiology, the term "environmental exposure" is often used to describe the contact between an individual and a potentially harmful environmental agent, such as air pollution or contaminated water. These exposures can have significant impacts on human health, contributing to a range of diseases and disorders, including respiratory illnesses, cancer, neurological disorders, and reproductive problems.

Efforts to protect and improve the environment are therefore critical for promoting human health and preventing disease. This includes measures to reduce pollution, conserve natural resources, promote sustainable development, and mitigate the impacts of climate change.

In medical terms, triplets are a type of multiple pregnancy, where three offsprings (fetuses) develop simultaneously in the uterus of a single pregnant woman. This occurs when a woman releases more than one egg during ovulation, and all three eggs get fertilized by separate sperm cells. Triplets can also occur through the use of assisted reproductive technologies such as in vitro fertilization (IVF) where multiple embryos are transferred into the uterus.

Triplet pregnancies carry a higher risk of complications for both the mother and the offsprings compared to singleton or twin pregnancies, including preterm labor, low birth weight, and developmental issues. As such, they often require close monitoring and specialized care throughout the pregnancy.

Multiple pregnancy is a type of gestation where more than one fetus is carried simultaneously in the uterus. The most common forms of multiple pregnancies are twins (two fetuses), triplets (three fetuses), and quadruplets (four fetuses). Multiple pregnancies can occur when a single fertilized egg splits into two or more embryos (monozygotic) or when more than one egg is released and gets fertilized during ovulation (dizygotic). The risk of multiple pregnancies increases with the use of assisted reproductive technologies, such as in vitro fertilization. Multiple pregnancies are associated with higher risks for both the mother and the fetuses, including preterm labor, low birth weight, and other complications.

Monozygotic twinning, also known as identical twinning, is a type of twin pregnancy that occurs when a single fertilized egg (ovum) splits into two embryos during the early stages of development. This results in the formation of two genetically identical individuals who share the same set of DNA and are therefore considered to be genetic clones of each other.

Monozygotic twinning is thought to occur in about 1 in every 250 pregnancies, making it less common than dizygotic (fraternal) twinning, which occurs when two separate eggs are fertilized by two different sperm. In monozygotic twinning, the timing of the split determines the type of placenta and amniotic sac each twin will have.

If the split occurs within the first few days after fertilization, the twins will typically develop in separate amniotic sacs and have their own individual placentas. If the split occurs later, the twins may share an amniotic sac (monoamniotic) or a placenta (monochorionic), or both (monochorionic-monoamniotic).

Monozygotic twinning is associated with some increased risks for pregnancy complications, such as preterm labor and delivery, low birth weight, and twin-to-twin transfusion syndrome, a rare condition in which blood flows unevenly between the twins through shared placental blood vessels. However, most monozygotic twins are born healthy and develop normally.

Pregnancy is a physiological state or condition where a fertilized egg (zygote) successfully implants and grows in the uterus of a woman, leading to the development of an embryo and finally a fetus. This process typically spans approximately 40 weeks, divided into three trimesters, and culminates in childbirth. Throughout this period, numerous hormonal and physical changes occur to support the growing offspring, including uterine enlargement, breast development, and various maternal adaptations to ensure the fetus's optimal growth and well-being.

Gene-Environment Interaction (GEI) is a concept in genetics that refers to the way in which genetic variations and environmental factors interact to influence traits or disease susceptibility. It describes a situation where the effect of an environmental exposure on a particular trait or disease outcome is dependent on the genetic makeup of the individual, and vice versa.

In other words, GEI suggests that the impact of environmental factors on health outcomes may be different depending on a person's genetic background, and similarly, the influence of certain genes on health outcomes may depend on the presence or absence of specific environmental exposures. This interaction can help explain why some individuals are more susceptible to certain diseases or traits than others, even when exposed to similar environments.

GEI is an important concept in precision medicine, as understanding these interactions can help identify individuals who are at higher risk for certain diseases and develop targeted prevention and treatment strategies based on their genetic and environmental profiles.

Behavioral genetics is a subfield of genetics that focuses on the study of the genetic basis of behavior. It seeks to understand how genes and environment interact to influence individual differences in behaviors such as personality traits, cognitive abilities, psychiatric disorders, and addiction. This field integrates knowledge from genetics, psychology, neuroscience, and statistics to investigate the complex relationship between genetic factors and behavioral outcomes. Research in behavioral genetics includes studies of twins, families, and adopted individuals, as well as animal models, to identify specific genes or genetic variations that contribute to the heritability of various behaviors. Understanding these genetic influences can provide insights into the prevention, diagnosis, and treatment of behavioral disorders.

A registry in the context of medicine is a collection or database of standardized information about individuals who share a certain condition or attribute, such as a disease, treatment, exposure, or demographic group. These registries are used for various purposes, including:

* Monitoring and tracking the natural history of diseases and conditions
* Evaluating the safety and effectiveness of medical treatments and interventions
* Conducting research and generating hypotheses for further study
* Providing information to patients, clinicians, and researchers
* Informing public health policy and decision-making

Registries can be established for a wide range of purposes, including disease-specific registries (such as cancer or diabetes registries), procedure-specific registries (such as joint replacement or cardiac surgery registries), and population-based registries (such as birth defects or cancer registries). Data collected in registries may include demographic information, clinical data, laboratory results, treatment details, and outcomes.

Registries can be maintained by a variety of organizations, including hospitals, clinics, academic medical centers, professional societies, government agencies, and industry. Participation in registries is often voluntary, although some registries may require informed consent from participants. Data collected in registries are typically de-identified to protect the privacy of individuals.

Inheritance patterns refer to the way in which a particular genetic trait or disorder is passed down from one generation to the next, following the rules of Mendelian genetics. There are several different inheritance patterns, including:

1. Autosomal dominant: A single copy of the altered gene in each cell is sufficient to cause the disorder. An affected parent has a 50% chance of passing on the altered gene to each offspring.
2. Autosomal recessive: Two copies of the altered gene in each cell are necessary for the disorder to occur. Both parents must be carriers of the altered gene and have a 25% chance of passing on the altered gene to each offspring, who may then develop the disorder.
3. X-linked dominant: The altered gene is located on the X chromosome, and one copy of the altered gene in each cell is sufficient to cause the disorder. Females are more likely to be affected than males, and an affected female has a 50% chance of passing on the altered gene to each offspring.
4. X-linked recessive: The altered gene is located on the X chromosome, and two copies of the altered gene in each cell are necessary for the disorder to occur. Males are more likely to be affected than females, and an affected male will pass on the altered gene to all of his daughters (who will be carriers) but none of his sons.
5. Mitochondrial inheritance: The altered gene is located in the mitochondria, the energy-producing structures in cells. Both males and females can pass on mitochondrial genetic disorders, but only through the female line because offspring inherit their mother's mitochondria.

Understanding inheritance patterns helps medical professionals predict the likelihood of a genetic disorder occurring in families and provides information about how a disorder may be passed down through generations.

Maternal Serum Screening (MSS) tests are a type of prenatal screening tests that measure the levels of certain substances in the mother's blood during pregnancy to assess the risk of birth defects or chromosomal abnormalities in the fetus. These tests typically measure the levels of two proteins, human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP), as well as a hormone called inhibin A.

The levels of these substances can vary depending on factors such as the gestational age of the fetus, the mother's weight, and the presence of certain medical conditions. By comparing the measured levels to established norms, healthcare providers can estimate the risk of chromosomal abnormalities such as Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and neural tube defects like spina bifida.

It is important to note that MSS tests do not provide a definitive diagnosis but rather an estimate of the risk. If the results suggest an increased risk, further diagnostic testing such as amniocentesis or chorionic villus sampling (CVS) may be recommended to confirm the diagnosis.

Fetofetal transfusion is a medical condition that can occur in pregnancies with multiple fetuses, such as twins or higher-order multiples. It refers to the transfer of blood from one fetus (donor) to another (recipient) through anastomotic connections in their shared placenta.

In some cases, these anastomoses can result in an imbalance in blood flow between the fetuses, leading to a net transfer of blood from one fetus to the other. This situation is more likely to occur when there is a significant weight or size difference between the fetuses, known as twin-to-twin transfusion syndrome (TTTS).

In TTTS, the recipient fetus receives an excess of blood, which can lead to high-output cardiac failure, hydrops, and potential intrauterine demise. Meanwhile, the donor fetus may become anemic, growth-restricted, and at risk for hypovolemia and intrauterine demise as well. Fetofetal transfusion can be diagnosed through ultrasound evaluation and managed with various interventions, including laser ablation of anastomotic vessels or fetoscopic surgery, depending on the severity and gestational age at diagnosis.

I'm not sure I understand your question. "Denmark" is a country located in Northern Europe, and it is not a medical term or concept. It is the southernmost of the Nordic countries, and it consists of the Jutland peninsula and several islands in the Baltic Sea. The capital city of Denmark is Copenhagen.

If you are looking for information about a medical condition that may be associated with Denmark, could you please provide more context or clarify your question? I would be happy to help you with more specific information if I can.

Heredity, in medical terms, refers to the passing on of genetic characteristics from parents to their offspring through the transmission of genes. These genes carry the information that determines many traits, such as eye color, hair color, height, and certain health conditions. Heredity plays a significant role in understanding the causes of various diseases and disorders, as some are strongly influenced by genetic factors. However, it's important to note that environmental factors can also interact with genetic predispositions to influence the expression of these traits.

A quantitative trait is a phenotypic characteristic that can be measured and displays continuous variation, meaning it can take on any value within a range. Examples include height, blood pressure, or biochemical measurements like cholesterol levels. These traits are usually influenced by the combined effects of multiple genes (polygenic inheritance) as well as environmental factors.

Heritability, in the context of genetics, refers to the proportion of variation in a trait that can be attributed to genetic differences among individuals in a population. It is estimated using statistical methods and ranges from 0 to 1, with higher values indicating a greater contribution of genetics to the observed phenotypic variance.

Therefore, a heritable quantitative trait would be a phenotype that shows continuous variation, influenced by multiple genes and environmental factors, and for which a significant portion of the observed variation can be attributed to genetic differences among individuals in a population.

Birth weight refers to the first weight of a newborn infant, usually taken immediately after birth. It is a critical vital sign that indicates the baby's health status and is used as a predictor for various short-term and long-term health outcomes.

Typically, a full-term newborn's weight ranges from 5.5 to 8.8 pounds (2.5 to 4 kg), although normal birth weights can vary significantly based on factors such as gestational age, genetics, maternal health, and nutrition. Low birth weight is defined as less than 5.5 pounds (2.5 kg), while high birth weight is greater than 8.8 pounds (4 kg).

Low birth weight babies are at a higher risk for various medical complications, including respiratory distress syndrome, jaundice, infections, and developmental delays. High birth weight babies may face challenges with delivery, increased risk of obesity, and potential metabolic issues later in life. Regular prenatal care is essential to monitor fetal growth and ensure a healthy pregnancy and optimal birth weight for the baby.

Genetic predisposition to disease refers to an increased susceptibility or vulnerability to develop a particular illness or condition due to inheriting specific genetic variations or mutations from one's parents. These genetic factors can make it more likely for an individual to develop a certain disease, but it does not guarantee that the person will definitely get the disease. Environmental factors, lifestyle choices, and interactions between genes also play crucial roles in determining if a genetically predisposed person will actually develop the disease. It is essential to understand that having a genetic predisposition only implies a higher risk, not an inevitable outcome.

Genetic models are theoretical frameworks used in genetics to describe and explain the inheritance patterns and genetic architecture of traits, diseases, or phenomena. These models are based on mathematical equations and statistical methods that incorporate information about gene frequencies, modes of inheritance, and the effects of environmental factors. They can be used to predict the probability of certain genetic outcomes, to understand the genetic basis of complex traits, and to inform medical management and treatment decisions.

There are several types of genetic models, including:

1. Mendelian models: These models describe the inheritance patterns of simple genetic traits that follow Mendel's laws of segregation and independent assortment. Examples include autosomal dominant, autosomal recessive, and X-linked inheritance.
2. Complex trait models: These models describe the inheritance patterns of complex traits that are influenced by multiple genes and environmental factors. Examples include heart disease, diabetes, and cancer.
3. Population genetics models: These models describe the distribution and frequency of genetic variants within populations over time. They can be used to study evolutionary processes, such as natural selection and genetic drift.
4. Quantitative genetics models: These models describe the relationship between genetic variation and phenotypic variation in continuous traits, such as height or IQ. They can be used to estimate heritability and to identify quantitative trait loci (QTLs) that contribute to trait variation.
5. Statistical genetics models: These models use statistical methods to analyze genetic data and infer the presence of genetic associations or linkage. They can be used to identify genetic risk factors for diseases or traits.

Overall, genetic models are essential tools in genetics research and medical genetics, as they allow researchers to make predictions about genetic outcomes, test hypotheses about the genetic basis of traits and diseases, and develop strategies for prevention, diagnosis, and treatment.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

Chimerism is a medical term that refers to the presence of genetically distinct cell populations within an individual. This phenomenon can occur naturally or as a result of a medical procedure such as a stem cell transplant. In natural chimerism, an individual may have cells with different genetic compositions due to events that occurred during embryonic development, such as the fusion of two fertilized eggs (also known as "twinning") or the exchange of cells between twins in utero.

In the context of a stem cell transplant, chimerism can occur when a donor's stem cells engraft and begin to produce new blood cells in the recipient's body. This can result in the presence of both the recipient's own cells and the donor's cells in the recipient's body. The degree of chimerism can vary, with some individuals showing complete chimerism (where all blood cells are derived from the donor) or mixed chimerism (where both the recipient's and donor's cells coexist).

Monitoring chimerism levels is important in stem cell transplantation to assess the success of the procedure and to detect any potential signs of graft rejection or relapse of the original disease.

The chorion is the outermost fetal membrane that surrounds the developing conceptus (the embryo or fetus and its supporting structures). It forms early in pregnancy as an extraembryonic structure, meaning it arises from cells that will not become part of the actual body of the developing organism. The chorion plays a crucial role in pregnancy by contributing to the formation of the placenta, which provides nutrients and oxygen to the growing embryo/fetus and removes waste products.

One of the most important functions of the chorion is to produce human chorionic gonadotropin (hCG), a hormone that signals the presence of pregnancy and maintains the corpus luteum, a temporary endocrine structure in the ovary that produces progesterone during early pregnancy. Progesterone is essential for preparing the uterus for implantation and maintaining the pregnancy.

The chorion consists of two layers: an inner cytotrophoblast layer and an outer syncytiotrophoblast layer. The cytotrophoblast layer is made up of individual cells, while the syncytiotrophoblast layer is a multinucleated mass of fused cytotrophoblast cells. These layers interact with the maternal endometrium (the lining of the uterus) to form the placenta and facilitate exchange between the mother and the developing fetus.

In summary, the chorion is a vital extraembryonic structure in pregnancy that contributes to the formation of the placenta, produces hCG, and interacts with the maternal endometrium to support fetal development.

I'm sorry for any confusion, but "Sweden" is not a medical term. It is a country located in northern Europe. If you have any questions about medical terminology or concepts, I would be happy to help answer those!

A "social environment" is not a term that has a specific medical definition, but it is often used in the context of public health and social sciences to refer to the physical and social conditions, relationships, and organized institutions that influence the health and well-being of individuals and communities.

The social environment includes factors such as:

* Social support networks (family, friends, community)
* Cultural norms and values
* Socioeconomic status (income, education, occupation)
* Housing and neighborhood conditions
* Access to resources (food, healthcare, transportation)
* Exposure to discrimination, violence, and other stressors

These factors can have a significant impact on health outcomes, as they can influence behaviors related to health (such as diet, exercise, and substance use), as well as exposure to disease and access to healthcare. Understanding the social environment is essential for developing effective public health interventions and policies that promote health equity and reduce health disparities.

I'm sorry for any confusion, but "siblings" is not a medical term. It is a term used in genealogy and sociology to refer to the brothers and sisters that someone has. Sibling relationships can have medical implications, such as when inherited genetic disorders are present in a family, but the term "siblings" itself does not have a specific medical definition.

I'm sorry for any confusion, but "Finland" is not a medical term. It is a country located in Northern Europe, known officially as the Republic of Finland. If you have any questions about medical terminology or health-related topics, I would be happy to try and help answer those for you.

A cohort study is a type of observational study in which a group of individuals who share a common characteristic or exposure are followed up over time to determine the incidence of a specific outcome or outcomes. The cohort, or group, is defined based on the exposure status (e.g., exposed vs. unexposed) and then monitored prospectively to assess for the development of new health events or conditions.

Cohort studies can be either prospective or retrospective in design. In a prospective cohort study, participants are enrolled and followed forward in time from the beginning of the study. In contrast, in a retrospective cohort study, researchers identify a cohort that has already been assembled through medical records, insurance claims, or other sources and then look back in time to assess exposure status and health outcomes.

Cohort studies are useful for establishing causality between an exposure and an outcome because they allow researchers to observe the temporal relationship between the two. They can also provide information on the incidence of a disease or condition in different populations, which can be used to inform public health policy and interventions. However, cohort studies can be expensive and time-consuming to conduct, and they may be subject to bias if participants are not representative of the population or if there is loss to follow-up.

Medical Definition:

"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.

Maternal age is a term used to describe the age of a woman at the time she becomes pregnant or gives birth. It is often used in medical and epidemiological contexts to discuss the potential risks, complications, and outcomes associated with pregnancy and childbirth at different stages of a woman's reproductive years.

Advanced maternal age typically refers to women who become pregnant or give birth at 35 years of age or older. This group faces an increased risk for certain chromosomal abnormalities, such as Down syndrome, and other pregnancy-related complications, including gestational diabetes, preeclampsia, and cesarean delivery.

On the other end of the spectrum, adolescent pregnancies (those that occur in women under 20 years old) also come with their own set of potential risks and complications, such as preterm birth, low birth weight, and anemia.

It's important to note that while maternal age can influence pregnancy outcomes, many other factors – including genetics, lifestyle choices, and access to quality healthcare – can also play a significant role in determining the health of both mother and baby during pregnancy and childbirth.

Tomasz Dziedzic, Ewa Fabianska, and Zuzanna Toeplitz (2007). Handwriting of Monozygotic and Dizygotic Twins. Problems of ... Even identical twins who share appearance and genetics do not have the same handwriting. Characteristics of handwriting include ... "On the Discriminability of the Handwriting of Twins". J Forensic Sci.; 53(2):430-46. ...
Lambalk, C.B. (Oct 25, 1998). "The endocrinology of dizygotic twinning in the human". Mol Cell Endocrinol. 145 (1-2): 97-102. ... or dizygotic, twins. This is because certain heritable variations of FSHB contribute to increased production of FSH from the ... "Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility". Am J Hum Genet. 98 ... This relates to having an increased risk of a woman bearing fraternal twins because higher levels of FSH will produce more eggs ...
A more recent study, where 114 monozygotic twins and 80 dizygotic twins were analyzed for the DNA methylation status of around ... Dizygotic (fraternal) and monozygotic (identical) twins show evidence of epigenetic influence in humans. DNA sequence ... February 2009). "DNA methylation profiles in monozygotic and dizygotic twins". Nature Genetics. 41 (2): 240-5. doi:10.1038/ng. ... epigenetic differences in monozygotic twins and implications for twin studies in psychiatry". American Journal of Medical ...
"Historique de la Mairie d'Oran". apc-oran.dz (in French). Oran. Retrieved 12 October 2020. "Partenariats internationaux". ... "Twinning". redditchbc.gov.uk. Redditch Borough Council. Retrieved 4 November 2020. "Twin towns". calderdale.gov.uk. Calderdale ... "Twin Towns of Wales: Hay-on-Wye and Timbuktu, Briton Ferry and Ouagadougou, here are the sister cities of Welsh towns". ... "Twin Cities". wh.gov.cn. Wuhan. Retrieved 16 October 2020. Yankson, Eric (January 2021). "The ILA study group on the Role of ...
"Historique de la Mairie d'Oran". apc-oran.dz (in French). Oran. Retrieved 3 December 2020. (CS1 Turkish-language sources (tr), ... "Aqaba's twin city Urumchi donates medical equipment for COVID-19 response". adc.jo. Aqaba Development Corporation. 15 April ... "Twin towns". plovdiv.bg. Plovdiv. Retrieved 30 June 2019. "Братски градови и општине". indjija.net (in Serbian). Inđija. ... Lists of twin towns and sister cities in Asia, Jordan geography-related lists, Populated places in Jordan, Foreign relations of ...
"Historique de la Mairie d'Oran". apc-oran.dz (in French). Oran. Retrieved 2020-12-17. "Twin towns". plovdiv.bg. Plovdiv. ... These twin roles saw the city develop into a thriving multicultural center, characterized by a distinctive architectural ... Al-Waha Mokhatat Al-Haramain Kholais Al-Rhmanya Wadi al batin AL MADINAH JUDAYYIADAT ARAR AS SALWA al huda Jeddah is twinned ...
"Historique de la Mairie d'Oran". apc-oran.dz (in French). Oran. Retrieved 26 January 2021. "Hermanamientos". lapaz.bo (in ... "Twin towns of Minsk". minsk.gov.by. Minsk. Retrieved 26 January 2021. "Mobile's Sister Cities". ncsmobile.org. City of Mobile. ... "Twin Cities". glasgow.gov.uk. Glasgow City Council. Retrieved 22 January 2021. "Honolulu Sister Cities". hnlsistercity.org. ... In most cases, the association, especially when formalised by local government, is known as "town twinning" (usually in Europe ...
"Historique de la Mairie d'Oran". apc-oran.dz (in French). Oran. Retrieved 17 December 2020. "Twin towns". plovdiv.bg. Plovdiv. ... "Twin towns of Minsk". minsk.gov.by. Minsk. Retrieved 16 September 2020. "عون الشوا من الفترة ما بين 1994 وحتى 2001". gaza-city. ... "Town Twinning". mashhad.ir. Mashhad. Retrieved 18 June 2020. "Islamabad to get new sister city". dawn.com. Dawn. 5 January 2016 ... "Twin towns - Sister Cities to Central Asia Countries and Caucasus". orexca.com. OrexCA. Retrieved 12 March 2022. "Бухара и ...
The classic twin study compares monozygotic and dizygotic twins. If the monozygotic twins resemble each other much more closely ... Monozygotic, or identical, twins share 100% of their genes, while dizygotic, or fraternal, twins share on average 50% of their ... Early twin studies were replicated later using twins with OCD meeting DSM criteria and ascertainment of probands, but only a ... Twin Research and Human Genetics. 8 (5): 450-458. doi:10.1375/twin.8.5.450. Pauls, David L. (2010). "The Genetics of Obsessive- ...
So, it would make sense for twins to have a higher prevalence of left-handedness. Unlike monozygotic twins, dizygotic twins ... dizygotic twins are 14 percent and monozygotic twins are 14.5 percent. Using this data, it is theorized that twins have higher ... In another study, the frequency of right-handed and left-handed pairs of dizygotic twins is about 23%, while twins with both ... Specifically, 15 percent of monozygotic twins were left-handed while 13 percent of dizygotic twins were left-handed. ...
... and twins ('Hereditary predisposition to dizygotic twin-births in Norwegian peasant families' in 1926). Upon hearing of the ... Bonnevie, Kristine; Sverdrup, Aslaug (January 1926). "Hereditary predispositions to dizygotic twin-births in Norwegian peasant ...
... are due to experiences that one twin has but not the other twin. "Fraternal" or dizygotic (DZ) twins share only about 50% of ... Maudsley Bipolar Twin Study Minnesota Twin Family Study Twins Early Development Study NASA Twins Study The power of twin ... Dizygotic (DZ) twins also share C, but share, on average only 50% of their genes: so the correlation between fraternal twins is ... and dizygotic (fraternal) twins. If identical twins are considerably more similar than fraternal twins (which is found for most ...
When twins are born, they are fraternal twins and are dizygotic. When a calf is born, it usually weighs 60-70 lb (27-32 kg) and ... The gestation period in manatees lasts for 12-14 months, after which they give birth to one calf at a time, or rarely twins. ...
... identical twinned embryos. Reversade also researches the genetics of dizygotic and monozygotic twinning in humans. He has been ... This stable DNA mark could be employed to retrospectively assess if a person is a MZ twin even if his/her co-twin vanished in ... 2016-05-05). "Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility". ... Segal, Nancy L. (2017). Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins. Academic Press. p. 54. ISBN 978-0- ...
Studies involving humans often compare opposite-sex to same-sex dizygotic twins. Females of opposite-sex twin pairs are thought ... Rodgers, C.S.; Fagot, B.I.; Winebarger, A. (1998). "Gender-typed toy play in dizygotic twin pairs: a test of hormone transfer ... When it comes to humans, studies comparing dizygotic opposite-sex and same-sex twins suggest the phenomenon may occur, though ... Elkadi, S.; Nicholls, Mike; Clode, D. (1999). "Handedness in opposite and same-sex dizygotic twins: testing the testosterone ...
Monozygotic (identical) but not dizygotic (fraternal) twins tend to have similar sleep habits. Neurotransmitters, molecules ...
They used skin grafting to differentiate between monozygotic and dizygotic twins in cattle. Taking the earlier research of R. D ...
GDF9 mutations are present in women with premature ovarian failure, in addition to mothers of dizygotic twins. Three particular ... 2007). "Novel variants in growth differentiation factor 9 in mothers of dizygotic twins". J. Clin. Endocrinol. Metab. 91 (11): ... although GDF9 P103S is present in women with dizygotic twins as well as women with premature ovarian failure. Given the same ...
Rodgers, C.S.; Fagot, B.I.; Winebarger, A. (1998). "Gender-typed toy play in dizygotic twin pairs: a test of hormone transfer ... Resnick, S.M.; Gottesman, I.I.; McGue, M. (1993). "Sensation seeking in opposite-sex twins: an effect of prenatal hormones?". ...
"Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability ...
This mutation has only been described in one of two dizygotic African-American twins. The affected twin was a 27-year old man ... Other findings in the Y362H twin included a higher delta power (measured with EEG) during NREM compared to his unaffected twin ... the results showed that the twin carrying the Y362H mutation had a recovering total sleep time of 482 minutes, while his twin ... After deprivating them of sleep for over 38 hours, the researchers leading the study that described the pair of twins, total ...
... glasses wearing dizygotic fraternal twins/sororal twins. They almost say anything in unison and only appeared in two episodes. ... The Cadwells appear only in the episode, "Speed Shrinks". These kids are two twins similar to Hilda and Henry, but are somewhat ... Timmy and Jimmy Fortevoce are identical twins, members of Becky's hockey team- Jimmy plays centre and Timmy plays defence. ...
"Ossification of the posterior longitudinal ligament in dizygotic twins with schizophrenia: a case report". Modern Rheumatology ...
In addition, the identical twin concordance rate is 10%, whereas the dizygotic twin concordance rate is only 3%. Between 8 and ... "Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability ... "Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study". Scandinavian Journal of ...
Dizygotic (DZ) or fraternal twins (also referred to as "non-identical twins", "dissimilar twins", "biovular twins", and, ... Like any other siblings, dizygotic twins may look similar, particularly as they are the same age. However, dizygotic twins may ... Fraternal twins can be any of the following: Female-female twins: Sometimes called sororal twins (25%). Male-male twins: ... This condition means that blood from one twin is being diverted into the other twin. One twin, the 'donor' twin, is small and ...
The Yoruba present the highest dizygotic twinning rate in the world (4.4% of all maternities). They manifest at 45-50 twin sets ... Twins are very important for the Yoruba and they usually tend to give special names to each twin. The first of the twins to be ... "Yoruba Customs and Beliefs Pertaining to Twins". Twin Research. 5 (2): 132-136. doi:10.1375/1369052023009. PMID 11931691. ... Kehinde is the name of the last born twin. Kehinde is sometimes also referred to as Kehindegbegbon, which is short for; Omo ...
Dizygotic (fraternal) twins run in families; however, the man does not influence the chances of the woman having twins, even if ... the legend of the twin brothers who founded the city (Romulus and Remus) made the birth of twin boys a blessing, while twin ... Monozygotic (identical) twins do not run in families. The twinning is random, due to the egg splitting, so all parents have an ... 51% of twins and 91% of triplets are born preterm, compared to 9.4% in singletons. 14% of twins and 41% of triplets are even ...
Shared environment is approximated by the DZ correlation minus half heritability, which is the degree to which DZ twins share ... Fraternal or dizygotic (DZ) twins on average share half their genes (assuming there is no assortative mating for the trait), ... is approximately twice the difference in correlation between MZ and DZ twins, i.e. Falconer's formula H2=2(r(MZ)-r(DZ)). The ... and so identical or monozygotic (MZ) twins on average are twice as genetically similar as DZ twins. A crude estimate of ...
... but dizygotic conjoined twins are theoretically possible. "conjoined twin". Encyclopedia Britannica. Retrieved November 5, 2021 ... Conjoined twins - popularly referred to as Siamese twins - are twins joined in utero. It is a very rare phenomenon, estimated ... The 1999 movie Twin Falls Idaho portrays conjoined twin brothers who are played by two non-conjoined identical twin brothers, ... Parasitic twins (10%): Twins that are asymmetrically conjoined, resulting in one twin that is small, less formed, and dependent ...
Both monozygotic twins are more likely to be alcoholics and to develop liver cirrhosis than both dizygotic twins. Polymorphisms ...
DZ) twins is a complex trait with important contributions from both environmental factors and genetic disposition. Twins are ... relatively common and occur on average 13 times per 1000 maternities, though the twinning frequency varies over time and geogra ... with mothers of DZ twins reporting significantly more female family members with DZ twins than mothers of monozygotic twins. ... This variation is mostly attributed to the differences in DZ twinning rate, since the monozygotic twinning rate is relatively ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Retrieved from "http://en-i.demopaedia.org/wiki/Special:WhatLinksHere/Dizygotic_twins" ... Twin, dizygotic (redirect page) ‎ (← links) *Twin, biovular (redirect page) ‎ (← links) *Biovular twins (redirect page) ‎ (← ... Pages that link to "Dizygotic twins". ← Dizygotic twins. Jump to: navigation, search ...
... and with respect to Jakarta EE 10 and MicroProfile 6 they are dizygotic twins:. *Jakarta EE 10 *Wildfly supports all EE ...
Copy For Citation KARAKULAK U. N., Cengaver M. K., ALADAĞ KARAKULAK E., Maharjan N. ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, vol.15, no.1, pp.89, 2015 (SCI-Expanded) ...
Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ... title = "Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ... Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ... Erratum: Heriability of the P300 components of the event-related potential: A study of monozygotic and dizygotic twins ( ...
Example twin extended kinship data: DZ female data Description. Data for extended twin example ETC88.R ...
Handwriting of Monozygotic and Dizygotic Twins NCJ Number. 226840. Journal. Problems of Forensic Sciences ...
Nearly 50 members of ISIS have been arrested accross the country in Iran following recent twin terrorist attacks staged in ... Hana Saada , web redactor at DZ Breaking. PhD student. Bachelors degree in English Literature and Language at Bouzareah ...
Tomasz Dziedzic, Ewa Fabianska, and Zuzanna Toeplitz (2007). Handwriting of Monozygotic and Dizygotic Twins. Problems of ... Even identical twins who share appearance and genetics do not have the same handwriting. Characteristics of handwriting include ... "On the Discriminability of the Handwriting of Twins". J Forensic Sci.; 53(2):430-46. ...
Twins, Dizygotic * Twins, Monozygotic Grants and funding * WT_/Wellcome Trust/United Kingdom ... Here, we compared microbiotas across ,1,000 fecal samples obtained from the TwinsUK population, including 416 twin pairs. We ... 3 Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK. ...
... for DZ twinning, calculated based on the results of the DZ twinning GWAS, was significantly associated with DZ twinning in ... for DZ twinning, calculated based on the results of the DZ twinning GWAS, was significantly associated with DZ twinning in ... for DZ twinning, calculated based on the results of the DZ twinning GWAS, was significantly associated with DZ twinning in ... for DZ twinning, calculated based on the results of the DZ twinning GWAS, was significantly associated with DZ twinning in ...
... for dizygotic twins; 4.7 (95% CI = 3.9-5.6) for full siblings; 2.1 (95% CI = 1.5-3.0) for maternal half-siblings; 1.3 (95% CI ... The hazard ratio was 11.5 (95% confidence interval (CI) = 1.6-83.8) for monozygotic twins; 7.4 (95% CI = 1.0-55.3) ... Family and twin studies of Borderline Personality Disorder (BPD) have found familial aggregation and genetic propensity for BPD ... twins (100%), dizygotic (DZ) twins (50%), full siblings (50%), maternal half-siblings (25%), paternal half-siblings (25%), ...
... and included 68,494 SS and 53,808 OS dizygotic twin individuals above the age of 20 years from 31 twin cohorts ... dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal ... and the prevalence of being overweight or obese between men and women from OS and SS dizygotic twin pairs. The data were ... and birth year with the twin type as a predictor were carried out to compare height and BMI in twins from OS pairs with those ...
Size of the human corpus callosum is genetically determined: An MRI study in mono and dizygotic twins. Neuroscience Letters. ... Size of the human corpus callosum is genetically determined : An MRI study in mono and dizygotic twins. In: Neuroscience ... Size of the human corpus callosum is genetically determined: An MRI study in mono and dizygotic twins. / Scamvougeras, Anton; ... title = "Size of the human corpus callosum is genetically determined: An MRI study in mono and dizygotic twins", ...
Dizygotic twins Is the Subject Area "Dizygotic twins" applicable to this article? Yes. No. ...
The twins are always dizygotic. Some experts consider each pregnancy a separate entity. This theory is supported by reports in ... Both twins were eventually discharged home without complications. [149] Because twin didelphys pregnancies are rare, data in ... In an exceptional case, 1 twin was delivered by means of cesarean delivery at 25 weeks gestation, and the second twin was ... after delivery of the first twin. [147, 148, 149] Lactation is reported to occur after the birth of the second twin. [148] ...
96 dizygotic female (DZF) twin pairs, 73 dizygotic male (DZM) twin pairs, and 150 dizygotic opposite-sex (DZOS) twin pairs. In ... twin pairs and 0.5 for the dizygotic (DZ) twin pairs. C was constrained to be 1.0 in both MZ and DZ pairs. E refers to all the ... Studies on Finnish twins and twin families. Twin Research, 5, 366-371.Google Scholar ... The equality of means and variances between the MZ and DZ twins was tested in a saturated model in which the means and ...
Polyester White 2 Dz Per Case Price Per Dz- T-200 60/40 Cotton/Poly White 39x80x9 Twin ... Thomaston Mills T-200 Fitted Sheets Twin 39x80x9 60% Cotton 40% ... Polyester White 2 Dz Per Case Price Per Dz. ... Thomaston Mills T-200 Fitted Sheets Twin 39x80x9 60% Cotton 40% Polyester White 2 Dz Per Case Price Per Dz ... Thomaston Mills T-200 Fitted Sheets Twin 39x80x9 60% Cotton 40% ...
Dizygotic twinning in the Hawaiian monk seal Jennifer K. Schultz, Brenda L. Becker, Thea C. Johanos, Jessica U. Lopez, Lizabeth ... Microsatellite genotyping revealed all of these to be dizygotic twins, with low probability of false assignment (P , 0.001). On ... We explored the incidence of twinning in the Hawaiian monk seal (Monachus schauinslandi). We observed 7 sets of putative twins ... Twinning is extremely rare in pinnipeds. Instances in which a female is observed simultaneously nursing 2 pups may represent ...
And so do fraternal (dizygotic) twins.. And yet, the IQs of fraternal twins correlate no more than the IQs of non-twin siblings ... Identical twins IQs, on the other hand, correlate much more than either non-twin siblings or fraternal twins. ... One weakness of twin studies is that the twins shared the same environment for nine months, and its likely the nine prenatal ... One point about twin studies, across most species animals favor their kin. This could bias the twin studies if adoptive parents ...
A list of frequently used twin terms and acronyms from the Twins List. ... Dizygotic Fraternal twins. Literally, this means from two fertilized eggs. dw See dh. A , B , C , D , E , F , G , H , I , J , K ... See Twin-to-Twin Transfusion Syndrome Twin Skin If youve already had your twins, and you dont know what this is, count your ... Twin-to-Twin Transfusion Syndrome (TTTS) A disease of the placenta occurring in monochorionic or monoamniotic identical twins. ...
Hardin et al., "The estimated probability of dizygotic twins: a comparison of two methods." Twin Res Hum Genet. (2009) ... These twins could have different dads (but they probably dont).. Two Eggs, Two Dads. A woman has to release two eggs in a ... Sometimes twins can fuse into a single person, like this flower here. It almost never looks like this, though! (Image: ... This is the first step in making any fraternal twins.. The difference in this case is that each egg is fertilized by a ...
In this study, in a retrospective blinded analysis of stored twin samples, all 16 samples have been determined correctly, with ... the minimum total amount of cell-free fetal DNA must be higher to reach a comparable sensitivity and vanishing twins may cause ... two triplets and 38 twins), with two correctly identified trisomy 21 cases, confirmed by karyotyping. The remaining 38 samples ... Chen, K.; Chmait, R.H.; Vanderbilt, D.; Wu, S.; Randolph, L. Chimerism in monochorionic dizygotic twins: Case study and review ...
All fraternal (dizygotic) twins are DiDi-separate packaging for each kid. The issue is implantation. If the two fetuses implant ... Monochorionic twins have ten times the risk of abnormality that dichorionic twins do. The risk for DiMo twins-each kid in its ... Think of it like double bagging at the supermarket.) The luckiest type of twin is DiDi-each twin has its own amnion (inner sac ... The only other possibility I could think of was conjoined twins. Gimme the straight dope on twins please, Uncle Cecil! ...
The risk for identical twins is significantly higher. for Crohns than for UC. While in non-identical (dizygotic) twins the ... Twin studies. Since identical twins (monozygotic) share the same genetic material, twin studies help researchers understand ...
New twin-spindle VMC for large component machining September 2, 2021 CHIRON Group introduced the DZ 28 twin-spindle vertical ...
... twins as well as WBC and buccal epithelial cells of 80 dizygotic (DZ) twins using 12K CpG island microarrays. Here we provide ... based comparison of matched MZ and DZ twins showed significantly higher epigenetic difference in buccal cells of DZ co-twins (P ... DNA methylation profiles in monozygotic and dizygotic twins. Zachary A Kaminsky et al.. Abstract. Twin studies have provided ... 10-294). Although such higher epigenetic discordance in DZ twins can result from DNA sequence differences, our in silico SNP ...
  • In violation of Weinberg's Differential Rule, there are significantly more SS than OS pairs among dizygotic twins in nationally representative samples both in the UK and the USA. (medscape.com)
  • The proportion of SS pairs among dizygotic twins was 0.6043 ( t (325) = 3.838, P = 0.00015) in the UK and 0.5739 ( t (520) = 3.398, P = 0.00073) in the USA. (medscape.com)
  • Weinberg's Differential Rule may be incorrect in its assumption of independence of sexes within dizygotic pairs, and there may be evolutionary selection for SS, and against OS, dizygotic pairs. (medscape.com)
  • Second, recent research in developmental psychology and biology also questions the independent determination of sexes in DZ twin pairs. (medscape.com)
  • Results: A total of 2178 monozygotic, 3219 same-sex dizygotic, and 3014 unlike-sex dizygotic twin pairs provided information. (elsevierpure.com)
  • In men, the intraclass correlation for reflux was 0.29 (95% confidence interval [Cl], 0.15-0.43) for monozygotic and 0.13 (95% Cl, 0.02-0.25) for dizygotic pairs. (elsevierpure.com)
  • In women, the correlation was 0.33 (95% Cl, 0.22-0.44) for monozygotic and 0.14 (95% Cl, 0.04-0.24) for dizygotic pairs. (elsevierpure.com)
  • For unlike-sex dizygotic pairs, the correlation was 0.06 (95% Cl, -0.01 to 0.14). (elsevierpure.com)
  • Conclusions: The increased concordance for reflux in monozygotic pairs, compared with dizygotic pairs, indicates genetic rather than shared environmental effects. (elsevierpure.com)
  • We studied 4042 Vietnam era veteran monozygotic and dizygotic male twin pairs to determine the effects of heredity, shared environment, and unique environment on the liability for 15 self-reported posttraumatic stress disorder symptoms included in the symptom categories of reexperiencing the trauma, avoidance of stimuli related to the trauma, and increased arousal. (nih.gov)
  • Symptoms in the reexperiencing cluster and one symptom in the avoidance and numbing cluster are strongly associated with combat exposure, and monozygotic pairs are more highly concordant for combat exposure than dizygotic pairs. (nih.gov)
  • There were no significant differences in site concordance of EH within the MZ twin pairs compared with DZ twin pairs when only presence of EH was considered, whereas a greater concordance was noted between MZ twin pairs compared with DZ twin pairs when both presence and absence of EH were considered. (edu.au)
  • Data were collected from 10 adult twin pairs (5 MZ, 5 DZ) in which both twins already had a SARS-CoV-2 infection. (frontiersin.org)
  • The aims of the current study were to estimate the relative influence of genetic and environmental factors on objective intermediate asthma phenotypes and, more importantly, to what extent correlations between these intermediate phenotypes can be explained by genetic and/or environmental factors using a sample of 103 young Dutch twin pairs. (ersjournals.com)
  • The authors used structural equation modelling to perform a meta-analysis of data from these studies and an existing twin study to estimate ALS heritability, and identified 171 twin pairs in which at least one twin had ALS. (bmj.com)
  • Results and discussion Five monozygotic twin pairs were concordant-affected, and 44 discordant-affected. (bmj.com)
  • No dizygotic twin pairs were concordant-affected, and 122 discordant-affected. (bmj.com)
  • Statistical models used to analyse twin data include "classical" analysis of variance components, and "twin differences" models that compare twins within monozygotic (MZ - identical) or dizygotic (DZ - fraternal) pairs. (twins.org.au)
  • This design allows treatments to be compared within twin pairs, which enables near-perfect (for MZ twins) or partial (for DZ twins) control for genetics and shared environment, removing noise from the treatment effect estimate. (twins.org.au)
  • gains in power (compared with assigning all twin pairs to the same group) will be achieved by comparing treatments within twin pairs assigned to differing interventions. (twins.org.au)
  • By analyzing twin pairs, researchers determined that most of the variability in the immune system is due to environmental factors, rather than genes. (nih.gov)
  • To determine the basis of immune system variation, a team led by Dr. Mark M. Davis at Stanford University School of Medicine applied the most recent advances in immune monitoring technologies to a classic research model: studying twin pairs. (nih.gov)
  • Twin pairs share the same prenatal environment and usually have a similar childhood environment. (nih.gov)
  • Of the 105 twin pairs, 78 were identical and 27 were fraternal. (nih.gov)
  • We estimated familial correlations in DNAm age for monozygotic (MZ) twin, dizygotic (DZ) twin, sibling, parent-offspring, and spouse pairs by cohabitation status. (sens.org)
  • These correlation patterns were best explained by cohabitation-dependent shared environmental factors, the effects of which were 1.41 (95% confidence interval [CI] 1.16 to 1.66) times greater for MZ pairs than for DZ and sibling pairs, and the latter were 2.03 (95% CI 1.13 to 9.47) times greater than for parent-offspring pairs. (sens.org)
  • An Internet bulletin board search and clinical contact requests for participants in a survey of twins in which one or both transitioned located 69 new twin pairs. (hawaii.edu)
  • Combining data from the present survey with those from past-published reports, 20% of all male and female monozygotic twin pairs were found concordant for transsexual identity. (hawaii.edu)
  • Methods: We compared concordance for reflux in monozygotic (MZ) and dizygotic (DZ) twins. (elsevierpure.com)
  • This study examined prevalence and site concordance of EH and opacity in the primary dentition of 2- to 4-year-old twins and singleton controls to assess the relative contribution of genetics and the environment to the aetiology of these defects. (edu.au)
  • Monozygotic twins have a much higher concordance rate than dizygotic twins. (merckmanuals.com)
  • Is the probability of having twins determined by genetics? (medlineplus.gov)
  • However, a few families with a larger-than-expected number of MZ twins have been reported, which indicates that genetics may play a role. (medlineplus.gov)
  • Shur N. The genetics of twinning: from splitting eggs to breaking paradigms. (medlineplus.gov)
  • Even identical twins who share appearance and genetics do not have the same handwriting. (wikipedia.org)
  • NIMH Grantee Art Petronis, M.D., Ph.D., University of Toronto, and colleagues, report on their findings in identical and fraternal twins in the February, 2009 issue of Nature Genetics . (nih.gov)
  • Therefore, comparing traits between MZ and DZ may help to capture the determining part of genetics and environmental factors. (frontiersin.org)
  • In a report published in the 2007 edition of the Journal of Human Genetics (per BBC ), the term semi-identical - or sesquizygotic - first surfaced as a descriptor for a type of twins. (scarymommy.com)
  • The former models allow the variance of health and other outcomes to be partitioned into components due to genetics, shared (familial) environment and non-shared (twin-specific) environment. (twins.org.au)
  • The latter models control for maternal and paternal factors, gestational age, geographical location and season of birth, age, ethnicity, sex (in MZ and same-sex DZ twins), and genetics (100% in MZ twins and 50% in DZ twins). (twins.org.au)
  • The responses of our twins relative to their rearing, along with our findings regarding some of their experiences during childhood and adolescence show their identity was much more influenced by their genetics than their rearing. (hawaii.edu)
  • Approximately 9% of ART singletons, 57% of ART twins, and 95% of ART triplets or higher-order multiples were low birthweight. (cdc.gov)
  • Similarly, 15% of ART singletons, 66% of ART twins, and 97% of ART triplets or higher-order multiples were born preterm. (cdc.gov)
  • at multiple sites and contains siblings (i.e., family_ID) and twins/triplets (i.e., sib). (nih.gov)
  • Are they all twins/triplets? (nih.gov)
  • Do you differentiate monozygotic (MZ) and dizygotic (DZ) twins/triplets? (nih.gov)
  • I hadn't even thought it might be twins, let along triplets, and we haven't got any in the family. (dailymail.co.uk)
  • For example, in one 2009 study published in the journal Neuropsychologia of 30,161 Finnish subjects between the ages of 18 and 69, left-handedness was more common in twins (8.1 percent) than in triplets (7.1 percent) and single borns (5.8 percent). (bestlifeonline.com)
  • Are There More Same-Sex Than Opposite-Sex Dizygotic Twins? (medscape.com)
  • It was in this context that the French statistician Jacques Bertillon (1874) first speculated that the number of DZ twins would equal twice the number of opposite-sex (OS) twins and that the remaining twins would be MZ. (medscape.com)
  • Using a sample of 3,349 (1,449 monozygotic (MZ), 1,105 dizygotic (DZ) same-sex (DZss) and 795 DZ opposite-sex (DZos)) twins, we showed that positive schizotypy, specifically, the perceptual and ideational components of schizotypy, correlated on a phenotypical level with neuroticism (Pearson's r=.37). (uni-muenchen.de)
  • This report is both a review of previously reported findings and the result of a specific research effort to find twins among whom one or both had transitioned from their assigned sex at birth to the gender typical of the opposite sex. (hawaii.edu)
  • Monochorionic diamniotic dizygotic (MCDADZ) twins are extremely rare. (e-kmj.org)
  • In a mo/di pregnancy (more scientifically referred to as a monochorionic diamniotic pregnancy) the twins share a chorionic sac, but have different amniotic sacs. (healthline.com)
  • In a mo/mo pregnancy (more scientifically referred to as a monochorionic monoamniotic pregnancy) the twins share both the chorionic and amniotic sacs. (healthline.com)
  • Multiple pregnancies in humans account for only 3% of pregnancies, 97-98% of which are twin pregnancies and the morbimortality is higher in the monochorionic twins when compared to dichorionic ones. (scielo.br)
  • The canine species is naturally multiparous, but the diagnosis of monochorionic twin pregnancy is not common. (scielo.br)
  • Case Report: Identification of Germline Chimerism in Monochorionic Dizygotic Twins. (cdc.gov)
  • Fraternal twins come from two eggs that are fertilized by two separate sperm and are no more alike than other siblings born to the same parents. (kidshealth.org)
  • On the other hand, fraternal twins only share about 50 percent of their chromosomes, as other siblings do. (healthline.com)
  • different numbers of subjects and siblings/twins per site. (nih.gov)
  • In this case, the twins only share 50 percent of their DNA, making them no more alike than non-twin siblings. (scarymommy.com)
  • And you'd be hard-pressed to find a person who isn't guilty of accidentally mixing up siblings in an identical twin set. (bestlifeonline.com)
  • In a di/di pregnancy (more scientifically referred to as a dichorionic diamniotic pregnancy) the twins each have their own chorionic and amniotic sacs. (healthline.com)
  • Dizygotic twins are always dichorionic and diamniotic, where each twin has its own chorionic and amniotic sac. (intechopen.com)
  • The two types of twins are classified as monozygotic and dizygotic. (medlineplus.gov)
  • There are two types of twins: monozygotic (identical) and dizygotic (fraternal). (kidshealth.org)
  • Unless you are a twin or have given birth to twins, you may be confused about the different types of twins and what their genetic makeups are. (healthline.com)
  • What are the "main" types of twins? (scarymommy.com)
  • Knowing how these types of twins are formed serves as an important basis for the understanding of semi-identical twins. (scarymommy.com)
  • It is possible that genes involved in sticking cells together (cell adhesion) may contribute to MZ twinning, although this hypothesis has not been confirmed. (medlineplus.gov)
  • Few specific genes in humans have been definitively linked with hyperovulation or an increased probability of DZ twinning. (medlineplus.gov)
  • The first large-scale study of its kind in twins has turned up evidence that we inherit instructions for the turning on and off of genes via mechanisms beyond the traditional sequence differences in the genetic code. (nih.gov)
  • Even though they share the same genes, identical twins often differ in important ways. (nih.gov)
  • By contrast, Petronis and colleagues suggest that fraternal twins also may differ more because they have more divergent sets of instructions for turning genes on and off. (nih.gov)
  • Although studies with adult twins on SARS-CoV-2 infection are rare so far, the fact that there is a genetic component associated with the highly variable clinical outcomes of COVID-19 has already been highlighted in recent studies investigating potential candidate genes and polymorphisms. (frontiersin.org)
  • However, gene-environment interactions may still be a source of differences between twins, and the search for candidate genes remains crucial on the road to personalized medicine. (frontiersin.org)
  • Dizygotic twins (DZ), who grow up together, are equally exposed to a comparable influence of environmental factors, but in contrast to MZ share only about 50% of their genes ( 3 ). (frontiersin.org)
  • Fraternal twins may be the same gender, they may have many of the same characteristics, but also may be very different from each other and, in fact, share half of their genes just like their sisters and brothers. (genome.gov)
  • If there is overlap in genes for two traits it is expected that the cross-twin cross-trait correlation will be higher in monozygotic (MZ) twins than in dizygotic (DZ) twins for these traits. (ersjournals.com)
  • Though rare, these sesquizygotic twins are the result of two sperm fertilizing a single egg, then the egg splits-so they have 100 percent match of their mother's genes and some odd percentage match of their father's. (bestlifeonline.com)
  • In twin studies, researchers compare identical (monozygotic) twins, who share almost all of their genes, with fraternal (dizygotic) twins, who share about half of their genes. (nih.gov)
  • Thus if identical twins show more similarity on a given trait compared to fraternal twins, it suggests that genes significantly influence that trait. (nih.gov)
  • Machin G. Familial monozygotic twinning: a report of seven pedigrees. (medlineplus.gov)
  • 14. A familial case of Kikuchi-Fujimoto disease in dizygotic twins. (nih.gov)
  • Traditional notions of heritability hold that fraternal twins differ more than identical twins simply because the former don't share the same DNA , the fixed sequence of letters in our genetic code. (nih.gov)
  • The heritability was 0.57 (95% CI, 0.45-0.69) amongst male twins, and 0.38 (0.26-0.50) amongst female twins. (nih.gov)
  • Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. (nih.gov)
  • A twin study would help determine whether this assumption is reasonable by allowing an estimate of ALS heritability. (bmj.com)
  • The British Motor Neuron Disease (MND) Twin Study 14 made a start on this process by reporting the likely range in which the ALS heritability value would lie: 0.38 to 0.85. (bmj.com)
  • 16 We have analysed these two new data sets with the existing data used for the British MND Twin Study, independently but simultaneously in a meta-analysis framework, to generate for the first time an estimate of ALS heritability. (bmj.com)
  • Study One: Substantial genetic overlap between Schizotypy and Neuroticism: A Twin Study Schizotypy can be seen as a cluster of personality traits, phenomologically similar to, yet expressed in an attenuated form compared to the full-blown features of schizophrenia spectrum disorders. (uni-muenchen.de)
  • Fraternal twins (also called dizygotic twins) result from the fertilization of two separate eggs with two different sperm during the same pregnancy. (genome.gov)
  • And the difference between fraternal and identical twins is that fraternal twins derive from two different eggs. (genome.gov)
  • It's important to recognize that the difference between fraternal twins and monozygotic, or identical twins, is that monozygotic twins result from the fertilization of a single egg with a single sperm and then during the embryonic development, or during the cell splits, those massive eggs split into two individuals, which later develop into two offspring. (genome.gov)
  • Fraternal twins are also called dizygotic twins, because they come from two different eggs. (healthline.com)
  • With dizygotic twins, two separate sperm fertilize two separate eggs. (scarymommy.com)
  • Mothers are more likely to have twins if they have the genetic trait of releasing two eggs during their period. (scarymommy.com)
  • for fraternal twins, two eggs are fertilized. (bestlifeonline.com)
  • The prevalence of EH by teeth was 21% in monozygotic twins (MZ), 22% in dizygotic twins (DZ), and 15% in singleton controls. (edu.au)
  • Studies of the prevalence of autoimmune disease in monozygotic twins show that genetic as well as environmental factors (such as infection) are necessary for the disease to develop ( 6 ). (cdc.gov)
  • Since at least 1874, twin researchers have assumed that dizygotic twins were equally likely to be SS or OS (later formalized as Weinberg's Differential Rule). (medscape.com)
  • To explain how DZ twinning can run in families, researchers have looked for genetic factors that increase the chance of hyperovulation. (medlineplus.gov)
  • To pinpoint such divergences, the researchers searched for how often twins shared a common type of epigenetic mark created when a molecule called a methyl group attaches to a certain part of DNA. (nih.gov)
  • Semi-identical twins are so rare that some researchers don't expect another set will ever be confirmed. (scarymommy.com)
  • In a landmark 1990 study published in the journal Science , researchers studied more than 100 sets of twins who grew up apart. (bestlifeonline.com)
  • Before modern genetic knowledge and technology, it was impossible to determine the zygosity of same-sex (SS) twins with certainty, and it was therefore difficult to estimate accurately the population incidence of monozygotic (MZ) and dizygotic (DZ) twins. (medscape.com)
  • Twin pregnancies are categorized according to three factors, zygosity, chorionicity and amnionicity. (intechopen.com)
  • As a result, identical twins share the same genomes and are always the same sex. (genome.gov)
  • Monozygotic twins share 100 percent of their genomes, dizygotic 50 percent, and sesquizygotic share some percentage in the middle. (bestlifeonline.com)
  • Cells from cheek swabs revealed that patterns of methylation were more similar in identical than fraternal twins. (nih.gov)
  • Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins. (duke.edu)
  • A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins. (medlineplus.gov)
  • But even in identical twins, epigenetic differences were commonplace throughout the genome. (nih.gov)
  • The likelihood of conceiving twins is a complex trait, meaning that it is affected by multiple genetic and environmental factors, depending on the type of twins. (medlineplus.gov)
  • This type of twins is much more common. (kidshealth.org)
  • The type of twins (fraternal or identical) and the timing of their development affects whether the babies shared or had their own separate chorionic and amniotic sacs . (healthline.com)
  • Sometimes health care professionals identify same-sex twins as fraternal or identical based on ultrasound findings or by examining the membranes at the time of delivery. (healthychildren.org)
  • MZ twins occur in 3 to 4 per 1,000 births worldwide. (medlineplus.gov)
  • While the international rate of twin birth is 13.1 per 1,000 births, the average across the middle of Africa jumps to over 18 per 1,000. (bestlifeonline.com)
  • The town of Igbo-Ora, Nigeria, was long considered to be the city with the highest rate of twins, with the BBC citing as many as 45 to 50 twins for every 1,000 births there in the years between 1972 and 1982. (bestlifeonline.com)
  • In the more recent PLOS One study, the title of most twins in Africa goes to a small country called The Republic of Benin, which sees 27.9 twins per 1,000 births! (bestlifeonline.com)
  • In the case of the Brisbane sesquizygotic twins, the fertilized egg appears to have equally divided up the three sets of chromosomes into groups of cells which then split into two, creating the twins," Dr. Michael Gabbett, clinical geneticist and diagnostic genomics course coordinator at Queensland University, explained in a press release . (scarymommy.com)
  • In MCDADZ twin, vascular anastomosis occurs by sharing the placenta, then twin-twin transfusion syndrome or the confusion in blood typing or genetic test due to blood chimerism can occur. (e-kmj.org)
  • Well, if two twins share a chorion, they'll share one placenta. (healthline.com)
  • Twin-to-twin transfusion syndrome (TTTS): TTTS can occur in identical twin pregnancies that share a placenta. (blogarama.com)
  • Occasionally a family is told that their twins are fraternal based on placenta findings, when they are in fact identical. (healthychildren.org)
  • Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility. (medlineplus.gov)
  • But with twin births on the rise due to advances in fertility treatments , this rare type of twinning could become less of a mystery in the near future. (scarymommy.com)
  • After all, if you're trying to conceive (either naturally or via fertility treatments), there's a chance you'll wind up a mother of twins. (scarymommy.com)
  • In fact, only the second confirmed case of semi-identical twins was reported in 2019 by the New England Journal of Medicine . (scarymommy.com)
  • In the case of the twins reported in 2019 (who were born in 2014), they were found to be "100 percent identical on their mother's side and 78 percent identical on their father's side. (scarymommy.com)
  • A couple of theoretical reasons cast doubt on the second assumption-the independent determination of sexes in DZ twins-and thus the validity of WDR itself. (medscape.com)
  • Such twins are genetically distinct and can be of different sexes. (nih.gov)
  • All twins age 55 and older in the nationwide Swedish Twin Registry were invited to participate. (elsevierpure.com)
  • We have therefore collected twin data from two further sources: the Swedish Twin Registry 15 and the King's College Hospital Motor Neuron Disease Clinic Register. (bmj.com)
  • The Washington State Twin Registry suggests that mirror twins can traced back to the splitting of the fertilized egg in the womb: When the egg is split, it may already have a clear left and right side, leading to mirroring. (bestlifeonline.com)
  • The team took blood samples from 210 healthy twins, ranging in age from 8 to 82, who were part of a twin registry. (nih.gov)
  • Monden C, Pison G, Smits J. Twin Peaks: more twinning in humans than ever before. (medlineplus.gov)
  • While twins may confuse us humans, canines can sniff out their differences. (bestlifeonline.com)
  • The probability of dying from CHD given that one's twin partner already has died from CHD decreased with increasing age, particularly amongst males. (nih.gov)
  • The study of enamel hypoplasia (EH) and opacity in twins provides insights into the contribution of genetic and environmental factors in the expression of enamel defects. (edu.au)
  • Twin studies are an important methodological tool for recording genetic and environmental influences. (frontiersin.org)
  • Twin and family studies are widely used to estimate genetic and environmental contributions to atopic disease 5 , 6 . (ersjournals.com)
  • The multivariate classical twin design can help to estimate the degree to which the same genetic and environmental factors influence different intermediate phenotypes 7 . (ersjournals.com)
  • Research suggests that most cases of MZ twinning are not caused by genetic factors. (medlineplus.gov)
  • Other factors known to influence the chance of having DZ twins include the mother's age, ethnic background, diet, body type, and number of other children. (medlineplus.gov)
  • A brief overview of the factors that influence twinning is available from the UK National Health Service. (medlineplus.gov)
  • Factors contributing to increase EH in twins were neonatal complications including intubation. (edu.au)
  • For example, if one identical twin develops schizophrenia , the other twin is spared the illness in about half of cases - despite evidence that at least 70 percent of the risk for the disorder is traceable to genetic factors. (nih.gov)
  • Monozygotic twins (MZ) have an almost identical genetic constitution and are also exposed to a comparable influence of environmental factors when they grow up together. (frontiersin.org)
  • Different delivery options: Depending on various factors such as the position of the babies and any potential complications, a twin pregnancy may result in a vaginal delivery or a cesarean section (C-section). (blogarama.com)
  • 5) The etiology of onychophagia is unknown although genetic factors may be at play (it is more common in monozygotic than dizygotic twins). (aad.org)
  • However, recent research on the sex-specific nature of breastmilk suggests that OS twins might be at a developmental disadvantage relative to SS twins. (medscape.com)
  • The greater epigenetic divergences in fraternal twins suggests that some of our epigenome is inherited, since they developed from separate cells. (nih.gov)
  • Twin pregnancies are one of the most magical occurrences in nature. (scarymommy.com)
  • It is important to note that false negatives are not exclusive to Twin Pregnancies and can occur in any type of pregnancy. (blogarama.com)
  • Elevated hCG levels: Twin Pregnancies may result in higher levels of human chorionic gonadotropin (hCG), a hormone detected in pregnancy tests. (blogarama.com)
  • Excessive morning sickness: Twin pregnancies are often associated with more severe morning sickness (nausea and vomiting) due to higher hormone levels. (blogarama.com)
  • Higher risk of complications: Twin pregnancies have a higher risk of certain complications, such as preterm birth, gestational diabetes, preeclampsia, placental abnormalities, and fetal growth restriction. (blogarama.com)
  • More intense pregnancy symptoms: Twin pregnancies often come with more pronounced pregnancy symptoms due to higher hormone levels. (blogarama.com)
  • Preeclampsia: Twin pregnancies have a higher risk of developing preeclampsia, a condition characterized by high blood pressure and organ damage. (blogarama.com)
  • Monozygotic twins account for 1/3 of twin pregnancies and show higher morbidity and mortality. (intechopen.com)
  • Morbitidies are shown notable decreasing tendency depending on improving of high risk obstetric and neonatal care, however is still discussed the optimum labour management in twin pregnancies Vaginal delivery in twin pregnancies is possible when both have cephalic presentation and in the late weeks of pregnancy during which the risks of prematurity are minimized. (intechopen.com)
  • The aim of this review was the assessment and evaluation the impact of the labour modus and timing of termination of twin pregnancies due to rise of their occurrence based on scientific aspects of the new published literature on perinatal outcome. (intechopen.com)
  • MZ twins share a more similar environment than DZ twins, so the difference between MZ and DZ may not be genetic at all, but instead environmental influences. (brainscape.com)
  • This may mean a twin pregnancy, triplet pregnancy, or more. (kidshealth.org)
  • A typical, single pregnancy lasts about 40 weeks, but a twin pregnancy often lasts between 35 to 37 weeks. (kidshealth.org)
  • When someone talks about twins they are referring to two babies that develop during the same pregnancy, but this can happen in many different ways. (healthline.com)
  • Is it possible for Twins to cause a pregnancy test to show a negative result when a person is actually pregnant? (blogarama.com)
  • In some cases, the hormone levels produced by a twin pregnancy may not be detected by the pregnancy test, leading to a false negative result. (blogarama.com)
  • What are the signs and symptoms of a twin pregnancy? (blogarama.com)
  • Rapid weight gain: Women carrying twins often experience more significant weight gain early in pregnancy due to the increased size and number of the developing babies. (blogarama.com)
  • How does a twin pregnancy differ from a singleton pregnancy? (blogarama.com)
  • Increased weight gain and size: Women carrying twins tend to experience more rapid weight gain and a larger increase in overall size compared to those with a singleton pregnancy. (blogarama.com)
  • What are the potential risks and complications associated with a twin pregnancy? (blogarama.com)
  • A twin pregnancy carries certain risks and complications that are important to be aware of. (blogarama.com)
  • Preterm birth: Twins are more likely to be born prematurely, meaning before the 37th week of pregnancy. (blogarama.com)
  • Chorionicity and amnionicity determine the risks of twin pregnancy. (intechopen.com)
  • Monozygotic (MZ) twins, also called identical twins, occur when a single egg cell is fertilized by a single sperm cell. (medlineplus.gov)
  • Dizygotic (DZ) twins, also called fraternal twins, occur when two egg cells are each fertilized by a different sperm cell in the same menstrual cycle. (medlineplus.gov)
  • Girl-boy twins occur when one X egg is fertilized with an X sperm, and a Y sperm fertilizes the other X egg. (healthychildren.org)
  • Somewhere between fraternal and identical, these twins share 100 percent of DNA on their mother's side, but only about 50 percent on their father's side. (scarymommy.com)
  • The best way to determine if twins are identical or fraternal is by examining each child's DNA. (healthychildren.org)
  • There are a few commercial laboratories that, for a fee, will send families DNA collection kits to determine if the twins are identical or fraternal. (healthychildren.org)
  • We considered for our study twin persons, male or female, identical or fraternal, within which one or both have transitioned from female to male (FtM) or male to female (MtF). (hawaii.edu)
  • Identical, or monozygotic, twins may or may not share the same amniotic sac, depending on how early the single fertilized egg divides into 2. (healthychildren.org)
  • There is a higher incidence of twins across Central Africa than any other area in the world, according to research published in 2011 in PLOS One . (bestlifeonline.com)
  • Other times, a family may see the minor differences in identical twins and declare the twins fraternal based on these differences in appearance. (healthychildren.org)
  • With a background in studying the relationship of twinning and homosexuality (Whitam, Diamond, & Martin, 1993) and uncovering the twins involved in the John/Joan case (M. Diamond & Sigmundson, 1997) as well as having reported on conjoined twins (M. Diamond, 1999) all due to a long term interest in sexual development (M. Diamond, 1965, 2006, 2011a), immediately piqued curiosity and initiated a search as to previous findings. (hawaii.edu)
  • Unless the twins are different genders , the assumption at birth may just be that they're identical. (scarymommy.com)
  • The equal environment assumption of the classic twin study might not hold for epigenetic aging. (sens.org)
  • These twins are genetically identical, with the same chromosomes and similar physical characteristics. (kidshealth.org)
  • Because identical twins come from the same egg/sperm, their chromosomes will be identical, which means they will be the same sex and have the same genetic characteristics (e.g., hair and eye color). (healthline.com)
  • In contrast, identical twins (or monozygotic twins) result from the fertilization of a single egg by a single sperm, with the fertilized egg then splitting into two. (genome.gov)
  • Identical twins are created when one egg and sperm meet like normal. (healthline.com)
  • With monozygotic twins, a single egg is fertilized by two different sperm. (scarymommy.com)
  • Okay, so we have a basic grasp of what happens to create semi-identical twins: A single egg splits after being fertilized by two sperm. (scarymommy.com)
  • Well, with half-identical twins, a single egg splits and then each of its halves meets and gets fertilized by sperm. (scarymommy.com)
  • We performed a one-sample t -test of the proportion of SS dizygotic twins against the theoretical null value of 0.5022. (medscape.com)
  • In order to achieve a better comprehension of ECCI contrasts of twin-boundary and stacking fault, an original theoretical approach based on the dynamical diffraction theory is used. (mdpi.com)
  • therefore, DZ twins would be equally likely to be SS as OS. (medscape.com)
  • Although there was no twin-twin transfusion syndrome or disconcordant blood-typing in our twins, genetic counseling and long-term follow up is needed for possible confusion in laboratory test due to persistent blood chimerism in the future. (e-kmj.org)
  • 선천성 혈액 한정키메라증은 이란성 쌍둥이(dizygotic twin)에서 태아-태아혈액 사이의 교환으로 인해 생기는 쌍둥이 혈액한정 키메라증이 대표적이며, 혈액형이나 유전검사에서 우연히 발견되거나 쌍둥이간 수혈증후군(Twin-twin transfusion syndrome)으로 발견되는 경우가 있다. (e-kmj.org)
  • When twins participate in an RCT, they can be randomised to the same treatment group (a form of cluster randomisation), or one twin can be assigned to the intervention group and the other to the control group (a "co-twin intervention" design), or randomised independently in which case they may can be randomised to the same or different treatment groups. (twins.org.au)
  • Because twins share their parents and parental condition, they are more likely to be SS-either both male if the parental condition is good or both female if the parental condition is poor. (medscape.com)
  • Like the chorion, twins can either share an amnion or have one all of their own. (healthline.com)
  • Not only are your babies born with a built-in best friend, but they will also share a special connection with that BFF for the rest of their lives - twins have support before they even get out of the womb. (scarymommy.com)
  • About 25 percent of identical twins are mirror images of one another, according a 2012 article in Scientific American . (bestlifeonline.com)
  • Twins were studied that are concordant or discordant for gender identity status in order to provide clarification of this issue. (hawaii.edu)
  • Twin type (monozygotic versus dizygotic) was classified by the mother, not by DNA typing, although supplementary data suggest that misclassification was negligible and supplementary analysis shows that potential misclassifications do not change our main conclusions. (medscape.com)
  • For example, Fellman and Eriksson (2006) analyzed twin data from Sweden and Finland, and concluded that 'WDR is robust and, despite its simplicity, gives reliable results when large national birth registers are considered' (p. 254). (medscape.com)
  • Healthy adults' data ( N = 953 [41% twins]) were analysed from the PREDICT dietary intervention trial. (springer.com)
  • The study sample consisted of 88 twin children and 40 singletons aged 2-4 years of age. (edu.au)
  • The study checked for the telltale marks at 6,000 chromosomal locations in cells from three different types of tissue - blood, cheek and gut - in 100 sets of identical and fraternal twins. (nih.gov)
  • This is the first study of adult monozygotic (MZ) and dizygotic (DZ) twins concordantly affected by SARS-CoV-2 infection to estimate variances explained by genetic, shared, and individual environmental components of both somatic and psychological symptoms following SARS-CoV-2 infection. (frontiersin.org)
  • The cohort drawn for the present study includes 20 966 twins born in Sweden between 1886 and 1925 where both twins within a pair still lived within the country in 1961. (nih.gov)
  • The families participating in the asthma study were a sample of a larger number of Dutch twin families who participated in the Netherlands Twin Register (NTR), an ongoing survey study of health-related behaviour 8 - 10 . (ersjournals.com)
  • In a 2011 study published in the journal PLOS One , German shepherd police dogs were presented with the scents of identical twins. (bestlifeonline.com)
  • A letter from a set of identical twin sisters alerted me that one, but not the other, would be transitioning to live as a man and asking if they might be useful in a study of transsexuality. (hawaii.edu)
  • It became clear that transsexuality among twins had, indeed, been reported but that no directed study of the phenomenon had been done. (hawaii.edu)
  • We also advertised our desire to study relevant twins by posting our request for subjects on different Internet websites (see Appendix). (hawaii.edu)
  • Trials that include twins pose practical, methodological and ethical difficulties, but these can be overcome with careful design and implementation. (twins.org.au)
  • The search yielded 43 sets of twins from available sources (Tables 1 and 2). (hawaii.edu)
  • If you've found out you're having twins (or just recently met a family with a pair of twins), you may wonder, how did this happen? (healthline.com)
  • Who among us hasn't been fascinated by the connection between a pair of twins , especially their ability to communicate without saying a word? (bestlifeonline.com)
  • We report dizygotic twins with HGPPS that had absence of conjugate horizontal eye movements combined with divergent strabismus and synergistic divergence. (nih.gov)
  • Authors report a case of MCDADZ twin who showed blood chimerism detected by karyotyping and chromosome microarray. (e-kmj.org)
  • Though the dogs were already trained to track down individual scents, according to the report, they were able to pick out twins "even if they live in the same household and eat the same food," two things that make up our own personal perfumes. (bestlifeonline.com)