The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
Accumulation of serous fluid between the layers of membrane (tunica vaginalis) covering the TESTIS in the SCROTUM.
The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
Surgery performed on the male genitalia.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.
The main trunk of the systemic arteries.
Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.
The nonstriated involuntary muscle tissue of blood vessels.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Heat and stain resistant, metabolically inactive bodies formed within the vegetative cells of bacteria of the genera Bacillus and Clostridium.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
The vessels carrying blood away from the heart.
The susceptibility of CAPILLARIES, under conditions of increased stress, to leakage.
The vessels carrying blood away from the capillary beds.
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.
Resistance and recovery from distortion of shape.
The degree to which BLOOD VESSELS are not blocked or obstructed.
Obstruction of flow in biological or prosthetic vascular grafts.
The continuation of the axillary artery; it branches into the radial and ulnar arteries.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
A measurement of the thickness of the carotid artery walls. It is measured by B-mode ULTRASONOGRAPHY and is used as a surrogate marker for ATHEROSCLEROSIS.
A publication issued at stated, more or less regular, intervals.
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Individual's rights to obtain and use information collected or generated by others.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
The contents included in all or any segment of the GASTROINTESTINAL TRACT.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.
Rounded or pyramidal cells of the GASTRIC GLANDS. They secrete HYDROCHLORIC ACID and produce gastric intrinsic factor, a glycoprotein that binds VITAMIN B12.
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. (1/3315)

1. We examined whether endogenous inhibitors of NO synthesis are involved in the augmentation of intimal hyperplasia in rabbits with hyperglycaemia induced by alloxan. 2. Four weeks after the endothelial denudation of carotid artery which had been performed 12 weeks after alloxan, the intimal hyperplasia was greatly augmented with hyperglycaemia. The degree of hyperplasia was assessed using three different parameters of histopathological findings as well as changes in luminal area and intima: media ratio. 3. There were positive and significant correlations between intima:media ratio, plasma glucose, and concentrations of N(G)-monomethyl-L-arginine (L-NMMA) and N(G), N(G)-dimethyl-L-arginine (ADMA) in endothelial cells, that is, the intima:media ratio became greater as plasma glucose and endothelial L-NMMA and ADMA were increased. Furthermore, endothelial L-NMMA and ADMA were increased in proportion to the increase in plasma glucose. 4. In contrast, there were inverse and significant correlations between cyclic GMP production by carotid artery strips with endothelium and plasma glucose, between cyclic GMP production and endothelial L-NMMA and ADMA, and between the intima:media ratio and cyclic GMP production. 5. Exogenously applied L-NMMA and ADMA inhibited cyclic GMP production in a concentration-dependent manner. IC50 values were determined to be 12.1 microM for the former and 26.2 microM for the latter. The cyclic GMP production was abolished after the deliberate removal of endothelium from the artery strips. 6. These results suggest that the augmentation of intimal hyperplasia with hyperglycaemia is closely related to increased accumulation of L-NMMA and ADMA with hyperglycaemia, which would result in an accelerated reduction in NO production/release by endothelial cells.  (+info)

Studies on structural changes of the carotid arteries and the heart in asymptomatic renal transplant recipients. (2/3315)

BACKGROUND: The present study was designed to characterize early structural changes of large arteries in renal transplant recipients with no clinical evidence of cardiovascular disease and normal blood pressure values, and to analyse the relationship between arterial alterations and those of the heart. METHODS: Intima media thickness and atherosclerotic plaques of the carotid arteries as well as left ventricular geometry and function were examined in 35 asymtomatic renal transplant recipients and 29 age- and sex-matched healthy controls by high resolution B-mode ultrasound and by echocardiography. RESULTS: Intima-media thickness of the carotid arteries was significantly higher in renal transplant recipients (1.21+/-0.08 mm) than in healthy controls (0.74+/-0.04 mm) (P<0.001). Atherosclerotic plaques were found in the majority of renal transplant recipients (71% vs 14% in healthy controls, P<0.001). Left ventricular mass index was significantly increased in the group of renal transplant recipients (264+/-13 g, 146+/-7 g/m2) when compared with healthy controls (155+/-8 g, 83+/-4 g/m2) (P<0.001). Multiple regression analysis in renal transplant recipients showed that intima media thickness of the carotid arteries was significantly related to left ventricular mass index (P<0.02), but not to age, blood pressure, body mass index, serum creatinine, cholesterol and lipoprotein (a) levels. In the group of healthy controls, intima-media thickness of the carotid artery was related to age (P<0.002), but not to left ventricular mass index or the other independent variables. CONCLUSIONS: The present study documents pronounced intima-media thickening in asymptomatic renal transplant recipients. Atherosclerotic lesions are present in most renal transplant recipients with no clinical evidence of cardiovascular disease. We observed a parallelism between arterial wall thickening and left ventricular hypertrophy, although blood pressure levels were normal during haemodialysis therapy and after renal transplantation.  (+info)

Arterial damage induced by cryopreservation is irreversible following organ culture. (3/3315)

OBJECTIVES: The aim of the present study was to investigate the changes which occur to the arterial wall following cryopreservation and thawing and to determine whether these changes are reversible after a week of culture in an organ bath. MATERIALS AND METHODS: Rat iliac arterial segments were cryopreserved. Once thawed, the arterial segments were cultured for a period of 0, 1, 2, 4 or 7 days. Freshly isolated rat iliac vessels cultured for 7 days served as the control group. Evaluation was made of ultrastructural changes, the expression of metalloproteinase activity (MMP-1, MMP-3 and MMP-9) and the apoptotic state of cells. RESULTS: The freezing-thawing process induced damage to the arterial segments compared to fresh control vessels. After 1 week of culture, arteries showed a high degree of tissue degeneration. Only a few individual endothelial cells remained on the luminal surface. There was a gradual increase in the proportion of apoptotic cells. The sequential expression of MMP-1 during the first 2 days and subsequent expression of MMP-3 and MMP-9 were of most significance. CONCLUSIONS: Cryopreservation induced damage to the vessels which could not be reversed by organ culture. The changes observed in the expression of metalloproteinases may be indicative of the degenerative process which occurs in the extracellular matrix.  (+info)

Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. (4/3315)

The perivascular implantation of tissue-engineered endothelial cells around injured arteries offers an opportunity to study fundamental vascular physiology as well as restore and improve tissue function. Cell source is an important issue because the ability to implant either xenogeneic or allogeneic cells would greatly enhance the clinical applications of tissue-engineered grafts. We investigated the biological and immunological responses to endothelial cell xenografts and allografts in pigs 4 weeks after angioplasty of the carotid arteries. Porcine or bovine aortic endothelial cells were cultured within Gelfoam matrices and implanted in the perivascular space of 42 injured arteries. Both porcine and bovine endothelial cell grafts reduced the restenosis index compared with control by 54% and 46%, respectively. Perivascular heparin release devices, formulated to release heparin at twice the rate of release of heparan sulfate proteoglycan from endothelial cell implants, produced no significant reduction in the restenosis index. Endothelial cell implants also reduced occlusive thrombosis compared with control and heparin release devices. Host immune responses to endothelial implants were investigated by immunohistochemical examination of explanted devices and by immunocytochemistry of serum samples. The bovine cell grafts displayed infiltration of leukocytes, consisting primarily of lymphocytes, and caused an increase in antibodies detected in serum samples. Reduced cellular infiltration and no humoral response were detected in animals that received allografts. Despite the difference in immune response, the biological effects of xenografts or allografts did not differ significantly.  (+info)

Cross-sectional and 4-year longitudinal associations between brachial pulse pressure and common carotid intima-media thickness in a general population. The EVA study. (5/3315)

BACKGROUND AND PURPOSE: The cross-sectional and 4-year longitudinal associations between brachial pulse pressure (PP) and ultrasound measurements of common carotid intima-media thickness (CCA-IMT) were assessed. METHODS: A population of 957 volunteers aged 59 to 71 years was recruited from the electoral rolls of the city of Nantes (western France) and reexamined 4 years later. Longitudinal changes in PP and CCA-IMT were computed as the difference between 4-year follow-up and baseline values. RESULTS: Baseline CCA-IMT and PP were positively associated in both age- and sex-adjusted analysis (partial correlation coefficient=0.20, P<0.001) and in multivariate analysis adjusted for traditional cardiovascular risk factors and mean blood pressure (partial correlation coefficient=0.18, P<0.001). In longitudinal analysis, baseline PP was associated with the change in 4-year CCA-IMT (partial correlation coefficient=0.11, P<0.001), and baseline CCA-IMT was a predictor of the 4-year change in PP (partial correlation coefficient=0.10, 0.001+info)

Prevention of neointimal formation by a serine protease inhibitor, FUT-175, after carotid balloon injury in rats. (6/3315)

BACKGROUND AND PURPOSE: In vivo and vitro studies revealed the activation of thrombin and the complement system in vascular lesion formation during the process of atherosclerosis, along with pathological proliferation of smooth muscle cells. We examined the effect of the synthetic serine protease inhibitor FUT-175 (developed as a potent inhibitor of thrombin and the complement system) on vascular lesions using balloon dilatation-induced neointimal formation in the carotid artery of rats. METHODS: Sprague-Dawley (SD) rats underwent balloon dilatation injury of the left carotid artery to induce neointimal formation. Three groups of these rats (n=8, each) were treated with daily intraperitoneal injections of 1 of the following doses of FUT-175: 0.5, 1.0, or 2.0 mg/d in 1 mL of saline for 7 consecutive days. The control group (n=8) was similarly treated with 1 mL of saline for 7 days. The injections were started immediately after balloon injury. Two weeks after the injury, the left carotid arteries were perfusion-fixed, and the areas of the neointimal and medial layer were analyzed under a microscope. RESULTS: A morphometric analysis revealed that there were significant differences in the intima-media ratio between the 4 groups treated with vehicle (saline) or a low, medium, or high dose of FUT-175 (1.45+/-0.11, 1.08+/-0.06, 0.71+/-0.04, or 0.32+/-0.04, respectively). This suppression was achieved in a dose-dependent manner by the administration of FUT-175 after balloon injury. In the histological study, it was demonstrated that FUT-175 suppresses the production of platelet-derived growth factor (PDGF)-BB in the neointima and the medial smooth muscle cell layer. CONCLUSIONS: After balloon injury activated proteases that were inhibited by FUT-175 were demonstrated to have an essential role in the development of the pathological thickening of the arterial wall.  (+info)

Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. (7/3315)

BACKGROUND: Exposure to risk factors such as hypertension or hypercholesterolemia decreases the bioavailability of endothelium-derived nitric oxide (NO) and impairs endothelium-dependent vasodilation. Recently, a circulating endogenous NO synthase inhibitor, asymmetric dimethylarginine (ADMA), has been detected in human plasma. The purpose of this study was to examine the relationship between plasma ADMA and atherosclerosis in humans. METHODS AND RESULTS: Subjects (n=116; age, 52+/-1 years; male:female ratio, 100:16) underwent a complete history and physical examination, determination of serum chemistries and ADMA levels, and duplex scanning of the carotid arteries. These individuals had no symptoms of coronary or peripheral artery disease and were taking no medications. Univariate and multivariate analyses revealed that plasma levels of ADMA were positively correlated with age (P<0.0001), mean arterial pressure (P<0.0001), and Sigma glucose (an index of glucose tolerance) (P=0.0006). Most intriguingly, stepwise regression analysis revealed that plasma ADMA levels were significantly correlated to the intima-media thickness of the carotid artery (as measured by high-resolution ultrasonography). CONCLUSIONS: This study reveals that plasma ADMA levels are positively correlated with risk factors for atherosclerosis. Furthermore, plasma ADMA level is significantly correlated with carotid intima-media thickness. Our results suggest that this endogenous antagonist of NO synthase may be a marker of atherosclerosis.  (+info)

Immunohistochemical analysis of arterial wall cellular infiltration in Buerger's disease (endarteritis obliterans). (8/3315)

PURPOSE: The diagnosis of Buerger's disease has depended on clinical symptoms and angiographic findings, whereas pathologic findings are considered to be of secondary importance. Arteries from patients with Buerger's tissue were analyzed histologically, including immunophenotyping of the infiltrating cells, to elucidate the nature of Buerger's disease as a vasculitis. METHODS: Thirty-three specimens from nine patients, in whom Buerger's disease was diagnosed on the basis of our clinical and angiographic criteria between 1980 and 1995 at Nagoya University Hospital, were studied. Immunohistochemical studies were performed on paraffin-embedded tissue with a labeled streptoavidin-biotin method. RESULTS: The general architecture of vessel walls was well preserved regardless of the stage of disease, and cell infiltration was observed mainly in the thrombus and the intima. Among infiltrating cells, CD3(+) T cells greatly outnumbered CD20(+) B cells. CD68(+) macrophages or S-100(+) dendritic cells were detected, especially in the intima during acute and subacute stages. All cases except one showed infiltration by the human leukocyte antigen-D region (HLA-DR) antigen-bearing macrophages and dendritic cells in the intima. Immunoglobulins G, A, and M (IgG, IgA, IgM) and complement factors 3d and 4c (C3d, C4c) were deposited along the internal elastic lamina. CONCLUSION: Buerger's disease is strictly an endarteritis that is introduced by T-cell mediated cellular immunity and by B-cell mediated humoral immunity associated with activation of macrophages or dendritic cells in the intima.  (+info)

TY - JOUR. T1 - Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: A cross-sectional study. AU - Petersen, Kristina S. AU - Keogh, Jennifer B. AU - Meikle, Peter J. AU - Garg, Manohar L. AU - Clifton, Peter M. PY - 2017/1/6. Y1 - 2017/1/6. N2 - � 2017 Baishideng Publishing Group Inc. All rights reserved. AIM To determine the clinical and dietary predictors of common carotid artery intima media thickness (CCA IMT) in a cohort of subjects with type 1 and type 2 diabetes. METHODS Participants with type 1 (n = 23) and type 2 diabetes (n = 127) had mean and mean maximum CCA IMT measured using B mode ultrasound. Dietary intake was measured using a food frequency questionnaire. Clinical and dietary predictors of mean and mean maximum CCA IMT were determined using linear regression analysis adjusted for potential confounders. RESULTS The main predictors of mean and mean maximum CCA IMT were age and weight. After ...
The tunica intima (New Latin inner coat), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow. The tunicae of blood vessels are three layers-an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica adventitia). In dissection, the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles. The inner coat consists of: A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought ...
International Journal of Nephrology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focusing on the prevention, diagnosis, and management of kidney diseases and associated disorders. The journal welcomes submissions related to cell biology, developmental biology, genetics, immunology, pathology, pathophysiology of renal disease and progression, clinical nephrology, dialysis, and transplantation.
Aim: To investigate risk factors which impact on common carotid artery intima media thickness (IMT). Methods: A total of 86 obese children and adolescents and 22 healthy children and ...
Intima-media thickness (IMT), also called intimal medial thickness, is a measurement of the thickness of tunica intima and tunica media, the innermost two layers of the wall of an artery. The measurement is usually made by external ultrasound and occasionally by internal, invasive ultrasound catheters; see Intravascular ultrasound. Measurements of the total wall thickness of blood vessels can also be done using other imaging modalities. IMT is used to detect the presence of atherosclerosis in humans and, more contentiously, to track the regression, arrest or progression of atherosclerosis. Ultrasound IMT measurements were first proposed and validated in vitro by Paolo Pignoli in 1984 and further details were subsequently published in a highly cited article. The use of IMT as a non-invasive tool to track changes in arterial walls has increased substantially since the mid-1990s. Although IMT is predictive of future cardiovascular events, the usefulness of measuring change in IMT over time is ...
Differences in thyroid function status within the euthyroid range have been proposed to affect the development of (subclinical) atherosclerosis [1], as evidenced by a greater carotid artery intima media thickness and progression of coronary artery calcification in the context of low normal thyroid function, i.e. a higher thyroid stimulating hormone (TSH) or a lower free thyroxine (FT4) thyroid hormone in the euthyroid range [2,3]. Importantly, with respect to high density lipoproteins (HDL) the concept is emerging that abnormalities in function rather than low concentrations of HDL cholesterol per se may give rise to impaired atheroprotective potential of this lipoprotein fraction ...
This proposal is currently approved by CHR (#H9577-18534-03C, exp date 3/26/04); the purpose of this new application is to split the currently approved protocol into a separate protocol with a separate PI. Data collected and patients seen under the previously approved protocol will be carried over into this new separate protocol. This is a longitudinal observational study of HIV-infected patients and HIV-negative control patients, and individuals with autoimmune diseases. We plan to obtain measurement of carotid artery intima media thickness (IMT) using high resolution ultrasound as a noninvasive means for tracking atherosclerotic progression. In addition, patients will undergo ct scan for coronary calcium and single slice abdominal ct scan to assess visceral fat. We will also measure lipid and lipoprotein levels, inflammatory markers, markers of CMV infection, thrombotic markers, atherogenic lipoproteins, and markers of immune function. Immunophenotyping will be performed on freshly collected ...
C) Chest X-ray (Extra HK$160). D) Carotid Artery Intima Media Thickness (IMT) (Extra HK$990). E) Treadmill/Exercise ECG (Extra HK$1,980) (Evaluate the risk of coronary heart disease). F) Echocardiogram (Extra HK$2,700). (Evaluate cardiac function, overall contraction of the heart and blood flows in narrow tubes or backwards caused by valvular heard disease). G) 64 Slice CT Coronary Ca Score (Extra HK$2,000). (Delete any of coronary heart disease, blood lipid, calcium and other material accumulation). H) Healthy Heart Cell Assessment (Extra HK$1,730). ...
主動脈剝離(英語:aortic dissection;法語:dissection aortique;德語:Aortendissektion),又譯為「主動脈夾層」或「心血管動脈撕裂」,是因為主動脈血管內膜(英語:Tunica intima)受傷,使得血液可以流入主動脈壁各層之間,使血管層剝離(英語:Dissection (medical))的症狀[3]。大部份的情形下,在主動脈剝離時會有嚴重、撕裂狀的胸痛或是背痛(英語:Acute aortic syndrome)[1][2],同時會有嘔吐、冒汗、頭重腳輕等症狀[2]。因為無法提供足夠血液到其他器官,也會有像中風或腸繫膜缺血等症狀[2]。主動脈剝離後,因為無法提供心臟足夠的血液或是主動脈破裂(英語:Aortic rupture),可能很快會致命[2]。 主動脈剝離較常出現在有高血壓及主動脈瓣二葉畸形(英語:Bicuspid aortic ...
A previous animal study (16) reported a significant decrease of inflammation following implantation of dexamethasone-eluting stents in pig coronary arteries at 5 days. However, no beneficial effect on neointimal growth was observed at 28 days, which reinforces the need for appropriate animal models and drug dosage to simulate human atherosclerotic disease.. Furthermore, the local or systemic administration is of cardinal importance to determine the efficacy of glucocorticoids with respect to their antirestenotic properties. In contrast to corticosteroids, preclinical models using paclitaxel have shown effective suppression of neointima at short term. In a previous experimental model of healthy rabbits implanted with stents loaded with a lower dose of paclitaxel (42.0 μg), neointimal thickness was reduced by 48% compared to BMS at 28 days (12). However, as in our study, paclitaxel-DES were associated with significantly larger areas of fibrin deposition surrounding stent struts and sparse ...
Artery. Coloured transmission electron micrograph (TEM) of a transverse section through part of an artery. Red blood cells (erythrocytes, red) and platelets (pink) can be seen in the central canal (lumen). The lumen is lined with a layer called the tunica intima, which is made up of endothelial cells (blue) and elastic fibres (dark blue). This layer lies underneath a layer of smooth muscle called the tunica media (orange). The outermost layer of the artery is known as the tunica externa (red) which is mainly composed of collagen. Magnification: x400 when printed 10cm wide. - Stock Image C033/7106
The significance of the strong P2Y2 expression observed in balloon-induced intimal lesions is not clear. Nevertheless, this strong expression could reflect an increased reactivity to extracellular nucleotides with consequent modulation of proliferation or vasoreactivity. Indeed, extracellular nucleotides, particularly ATP and UTP, have been shown to induce cell cycle progression and proliferation of cultured arterial SMCs3 4 5 6 7 and to induce a vasoconstriction in the absence of endothelial cells.11 12 13 Since both neointimal hyperplasia and vasoconstrictive remodeling have been found to be involved in postangioplasty restenosis,1 30 31 32 our data suggest that extracellular nucleotides might play a significant role in this process, at least as long as the functional endothelial cells, which control intimal thickening33 34 and nucleotide vasorelaxant effects,35 36 are not regenerated.. The increased P2Y2 receptor expression in the neointima may by itself be sufficient to enhance the local ...
Cand vine vorba despre igiena intima parerile sunt impartite, iar discutiile sunt mereu controversate. Dorind sa aflu cat mai multe pareri despre produsele de igiena intima am provocat la discutii o serie de prietene si am dat o raita printre forumuri.. Imi este foarte clar ca fiecare femeie alege un produs de igiena intima in functie de convingerile legate de eficienta ingredientelor pe care le contine un produs X si pret 맥 음악 다운로드.. Nu sunt experta in ale produselor de igiena intima, dar sunt convinsa de faptul ca zona intima feminina are nevoie de atentie speciala si de produse create pentru igienta intima. Asa cum folosim produse destinate ingrijirii parului, mainilor, picioarelor, fetei, este important sa folosim un produs de igiena dedicat zonei intime - un produs cu actiune blanda care sa nu actioneze agresiv catia v5 r20.. In cautarile mele am aflat ca sunt femei care au o sensibilitate exagerata care dupa ce au incercat aproape toate produsele de igiena intima de pe piata, ...
Intimal re-layering technique for type A acute aortic dissection-reconstructing the intimal layer continuity to induce remodeling of the false channel
PhD Project - Exploring the similarities between neointimal formation after vascular injury and tumour growth at University of Bristol, listed on FindAPhD.com
Herbal Care Gel Calmant Pentru Igiena Intima Cu Extract De Albastrele Si Acid Lactic 330ml din magazinele online, 45 produse. Cele mai noi prețuri pentru 330ml. Herbal cumparaturi online.
Find and save ideas about Crioterapia para adelgazar on Pinterest. | See more ideas about Consejos para dieta limpia, Cuerpo sexy and Higiene intima femenina.
This report is the final of the Veterans and Agent Orange series, which was required by Public Law 102-4, The Agent Orange Act of 1991, and extended by Public Law 107-103. The Secretary of Veterans Affairs was directed to contract with the National ...
The triple line pattern on carotid intima media thickness imaging and its relationship to cardiovascular risk factors in patients on lipid lowering therapy Tania A Singh,1 Todd C Villines,2 Allen J Taylor31Division of Cardiology, Medstar Georgetown University Hospital, 2Walter Reed National Military Medical Center, Bethesda, MD, 3Georgetown University School of Medicine, Washington, DC, USA Background: Carotid intima media thickness (CIMT) infrequently identifies a triple line pattern (TLP) in the visualization of the internal elastic lamina. We examined the prevalence and predictors of the TLP among a consecutive series of subjects enrolled in a CIMT clinical trial, and also the effects of lipid lowering therapy.Methods: Baseline CIMT studies of subjects with known heart disease, or high risk for heart disease, were evaluated from a single site of the Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis trial (N
Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers in Asian Indians Surrogate sub clinical mar..
TY - JOUR. T1 - Thapsigargin inhibits smooth muscle cell proliferation and intima formation in human saphenous vein. AU - George, SJ. AU - Angelini, GD. AU - Jeremy, JY. PY - 1997. Y1 - 1997. M3 - Article (Academic Journal). VL - 17. SP - 2500. EP - 2506. JO - Arteriosclerosis, Thrombosis, and Vascular Biology. JF - Arteriosclerosis, Thrombosis, and Vascular Biology. SN - 1079-5642. ER - ...
Background: A metabolic syndrome associated with atherosclerosis and cardiovascular disease has been seen in HIV (+) individuals receiving highly active antiretroviral therapy (HAART). Functional vascular changes can be non-invasively assessed and may precede the development of atherosclerosis.. Methods: We measured carotid artery intima media thickness (IMT) and brachial artery flow-mediated dilatation (FMD) by vascular ultrasonography in 61 HIV (+) patients (mean age 41.8 ± 13 yrs, 88.5 % male) attending a tertiary care center, in 30 patients with angiographically documented CAD (positive control) and in 30 healthy subjects. Both control groups had similar age, sex and atherosclerotic risk factors to HIV infected patients. Carotid to femoral pulse wave velocity (PWV-Complior apparatus) was also measured in HIV (+) patients.. Results: By ANOVA, HIV patients had higher IMT than healthy controls and similar IMT to matched CAD patients (0.64±0.2 vs. 0.54±0.05 vs .0.66±0.08 mm respectively, ...
We have used carotid IMT rather than CHD as our outcome. Carotid IMT has been shown to be strongly associated with prevalent and incident CHD.13,18 It has been suggested that the difference in IMT between women and men may be explained by differences in luminal diameter.22 However, this has been shown not to be the case in the large Tromso study.14 There was a differential in the response between women and men in our study and a difference in the nature of the sampling frame for women and men. Men were survivors of a prospective cohort, whereas women were a newly selected random sample. While among the men responders did not appear to differ from non-responders with respect to age, women who responded were younger than those who did not and women were on average slightly younger than men in the final study sample. All results presented in this study are adjusted for age. Mean blood pressure, lipid levels, and waist-hip ratios for both women and men from this study are similar to those for ...
Continuous and dichotomous metabolic syndrome definitions in youth predict adult type 2 diabetes and carotid artery intima media thickness: the Cardiovascular Risk in Young Finns Study
The KEEPS is designed to explore the hypothesis that early initiation of hormone therapy, in women who are at the inception of their menopause, will decrease the rate of accumulation of atherosclerotic plaque, indicating a likely delay in the onset of clinical cardiovascular disease. The study is designed as a multicenter, 4 year randomized clinical trial. It will evaluate the effectiveness of of 0.45 mg/day of oral conjugated equine estrogens or 50 mcg/day of transdermal estradiol via skin patch changed weekly (each in combination with cyclic oral, micronized progesterone, 200 mg daily for 12 days per month), versus placebo in preventing progression of carotid intimal medial thickness by sonogram and the accrual of coronary calcium in women aged 42-58 who are within 36 months of their final menstrual period at initiation of treatment. A number of secondary endpoints including biochemical and genetic risk factors for cardiovascular and thrombotic disease, and effects on cognition will also be ...
The walls of all blood vessels, except the smallest, have three layers, or tunics, that surround a central blood-containing space, the vessel lumen.. The innermost tunic is the tunica intima. The tunica intima contains the endothelium, the simple squamous epithelium that lines the lumen of all vessels. The endothelium is continuous with the endocardial lining of the heart, and its flat cells fit closely together, forming a slippery surface that minimizes friction so blood moves smoothly through the lumen. In vessels larger than 1 mm in diameter, a subendothelial layer, consisting of a basement membrane and loose connective tissue, supports the endothelium.. The middle tunic, the tunica media, is mostly circularly arranged smooth muscle cells and sheets of elastin. The activity of the smooth muscle is regulated by sympathetic vasomotor nerve fibers of the autonomic nervous system and chemicals. Depending on the bodys needs at any given moment, regulation causes either vasoconstriction (lumen ...
The major finding of this study is that GIT1 is an important regulator of vascular remodeling. Specifically, we found that GIT1 depletion inhibited intima formation after carotid ligation by 50%. In vivo and in vitro analysis showed a key role for GIT1 in VSMC proliferation, migration, and apoptosis during vascular remodeling (Figure III in the online-only Data Supplement). Furthermore, GIT1 is required for VSMC proliferation through PLCγ and ERK1/2 by regulating the expression of cell cycle-related proteins, such as cyclin D1. GIT1 is also essential for cell survival by regulating VSMC apoptosis through PLCγ and cell migration through PLCγ and ERK1/2.. VSMC proliferation and migration are key components in vascular remodeling.1,2 The present study shows that GIT1 expression is highly regulated by AngII and PDGF in vitro, and during vascular remodeling in vivo. The role of GIT1 in mediating VSMC proliferation was demonstrated by several assays, including in vitro cell count, [3H]-thymidine ...
Bronner Handwerger, ND. Assessing cardiovascular risk factors is always part of the naturopathic intake. The question arises as to how we assess these risks. We recognize that traditional markers like cholesterol, HDL, LDL, Lp(a), fibrinogen, homocysteine and even cardio CRP provide us with valuable information, along with family history. Although these are important to assess, they still do not give us the kind of reliable information we are looking for.. Cardiovascular disease is the No. 1 killer in the U.S. for both men and women. Heart disease and stroke account for almost six million hospitalizations each year, and more than 40% of all people age 45 and older have some form of cardiovascular disease. Approximately 1.1 million Americans are expected to have a new or recurrent heart attack this year, and 60% of all deaths in the U.S. are attributed to cardiovascular disease. A more sobering statistic is that 40%-50% of all heart attack patients have a normal cholesterol or lipid profile, ...
Results A total of 76 patients were screened and 22 RA patients who were in low disease activity or remission were included. Patients with RA had significantly higher median cIMT, 0.53 (IQR0.13) mm compared to controls, 0.47 (IQR 0.14) mm, p=0.01. In RA patients, the cIMT had significant positive correlation with age (rs=0.84, p=0.00), systolic BP (rs=0.45, p=0.04), waist circumference (rs=0.43, p=0.04), total cholesterol (rs=0.54, p=0.01), BMI (rs=0.45, p=0.04) and serum IL-17 (rs=0.45, p=0.03) but negative correlation with total HDL (rs=-0.43, p=0.05). ...
Looking for internal elastic membrane? Find out information about internal elastic membrane. A sheet of elastin found between the tunica intima and the tunica media in medium- and small-caliber arteries Explanation of internal elastic membrane
TY - JOUR. T1 - Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs. AU - Eto, Yasuhiro. AU - Shimokawa, Hiroaki. AU - Hiroki, Junko. AU - Morishige, Kunio. AU - Kandabashi, Tadashi. AU - Matsumoto, Yasuharu. AU - Amano, Mutsuki. AU - Hoshijima, Masahiko. AU - Kaibuchi, Kozo. AU - Takeshita, Akira. PY - 2000/6. Y1 - 2000/6. N2 - Restenosis after angioplasty still remains a major problem for which neointimal formation appears to play an important role. Recent studies in vitro suggested that Rho kinase, a target protein of Rho, is important in various cellular functions. We thus examined whether Rho kinase is involved in the restenotic changes after balloon injury. In vivo gene transfer was performed immediately after balloon injury in both sides of the porcine femoral arteries with adenoviral vector encoding either a dominant negative form of Rho kinase (AdDNRhoK) or β-galactosidase (AdLacZ) as a control. One week after the transfer, ...
Vascular smooth muscle cells (VSMCs) proliferation and migration, that are central within the development of vascular diseases, are controlled by several hormones and humoral factors. D4 receptor suppresses the proliferation and migration of VSMCs, consequently, inhibit atherosclerosis. The D4 receptor could be a potential restorative target to lessen the consequences of insulin on artery redesigning. strong course=kwd-title Keywords: Dopamine receptor, BIBX1382 manufacture Insulin receptor, Vascular soft muscle tissue cell, Proliferation, Migration, Atherosclerosis Intro The irregular proliferation and migration of vascular soft muscle tissue cells (VSMCs) perform a crucial part in neointimal development and vascular redesigning during atherosclerosis and restenosis [1-3]. It really is currently approved that proliferation and migration of medial VSMCs get excited about neointimal development after injury, that could become induced by cytokines and development elements, including insulin. ...
The Common carotid intima media thickness (CCIMT), an established indicator of atherosclerosis and an important functional predictor of cardiovascular system3,9 can effectively be used to measure progress of atherosclerosis and also to assess the success of interventions 2,8.. What is known is that measurement of CCIMT by non-invasive B-mode ultrasonography can detect atherosclerosis at the earliest preclinical stage and help in the prediction and diagnosis of asymptomatic vascular disease.3,14,15. Our study demonstrates the factors which have the strongest correlation with CCIMT and hence with pan-atherosclerosis.. In the present study, comparison of the cases (Group I) with the age- and sex-matched controls (Group II), revealed a higher duration of diabetes, hypertension and dyslipidaemia in the latter Group 2. These patients also had a significantly higher mean CCIMT value. With these points in mind let us consider the correlation of risk factors with CCIMT in our patients. In our analysis, ...
In this study, placement of a cuff around the femoral artery was used to investigate the role of plasminogen and fibrinogen in neointima formation and compensatory vascular remodeling. A smooth muscle cell-rich neointima developed in the arteries of mice within 28 days after cuff placement and was associated with marked elastic lamina degradation. Homozygous deficiencies of plasminogen or fibrinogen did not affect the extent of either neointima formation or elastic lamina breakdown. However, plasminogen was found to be critical in compensatory remodeling, via fibrin-dependent mechanisms, and appeared to prevent medial atrophy independently of fibrinolytic mechanisms.. Like the sequence of events that occur during wound healing, an initial accumulation of inflammatory cells and deposition of fibrin occurred in the adventitia of the arteries, followed by subsequent fibrin clearance and collagen scar formation. Although the detailed mechanisms for neointimal development after cuff placement have ...
In a series of experiments examining neointimal lesion formation in injured rat arteries, it became apparent that the migration of SMCs into the intima was a critical event. Early work focused on the role of plasminogen activators and the formation of plasmin as a necessary protease for SMC migration.10,11⇓ Recently, we have become interested in the role of MMPs in neointimal growth. Arteries express MMP-9 within hours after injury and continue to do so for up to 7 days, and this is accompanied with an increase in MMP-2 activation.1 We hypothesized that these MMPs regulate SMC migration, because many metastatic cells express these same proteinases, and we know that SMCs migrate into the intima at times when MMP activity is increased (,7 days). Furthermore, we were able to block SMC migration in injured arteries by the administration of an MMP inhibitor, although the size of the neointimal lesion 14 days after injury was identical to that of injured control arteries.8 This occurred despite the ...
Background: Intima-Media thickness is an acknowledged surrogate marker for predicting and profiling of atherosclerotic cardiovascular disease. It displays geographical an..
Atherosclerosis is a vascular disorder involving inflammation, a narrowed vascular lumen in the entire tunica intima, and reduced elasticity of the arterial wall. It has been found that Hsp60 from Chlamydia pneumoniae, an obligate bacterial pathogen associated with atheroma lesions, mimics human Hsp …
Spirometry Ultrasonography Electro Cardiology (Ekg) Echocardiogram Holter Monitor Carotid Intima Media Thickness (CIMT) A scan that is one of the most accurate
VSMC and HUVEC proliferation and apoptosis were measured by BrdU and TdT staining, respectively. Balloon injury of the right carotid was produced in Wistar rats. Straight after the vascular injury, the balloon-dilated arteries were randomly transfected with p85active (n = 8), dominant negative p85 (p85DN) (n = 8) or green fluorescent protein (GFP, n = 6; controls). Transfection of p85active decreased VSMC proliferation in the absence of cAMP while cAMP inhibition of VSMC growth was prevented by p85DN. p85active formed a stable complex with ras proteins, resulting in a selective switch-off of ras effectors in VSMCs. On the other hand, p85active did not affect HUVEC growth in vitro. Interestingly, p85active significantly reduced VSMC and HUVEC apoptosis in vitro. In both vascular cell lineages, p85active increased while p85DN decreased Akt phosphorylation. Importantly, the in vivo transfection of activated p85-active significantly reduced VSMC proliferation and then neointimal formation after ...
A method is disclosed for inhibiting intimal hyperplasia in a warm-blooded mammal which comprises administering topically at the site and time of a vascular injury induced by arterial intervention in said mammal a small but inhibitorily effective amount of tissue factor pathway inhibitor (TFPI) sufficient to inhibit said intimal hyperplasia.
A method is disclosed for inhibiting intimal hyperplasia in a warm-blooded mammal which comprises administering topically at the site and time of a vascular injury induced by arterial intervention in said mammal a small but inhibitorily effective amount of tissue factor pathway inhibitor (TFPI) sufficient to inhibit said intimal hyperplasia.
.. Associated with decreased carotid artery intimal medial thickness (IMT), explained by genetic factors the tendency for this variant is to act in a recessive manner with effects on multiple traits, to include only individuals with U.S.-born parents and grandparents eliminated the stratification using the sum of the case-control allele frequency chi square, short tandem…
among patients given either simvastatin (40 mg/d) or atorvastatin leading proponents of the lipid hypothesis dominated the (80 mg/d), but declined over the next 2 years to a greater extent in subsequent extensive media coverage, enthusiastically hailing the latter group. A significant correlation was found between the these results as triumphant confirmation of the PROVE-IT decrease of CRP and reduction in intima media thickness (IMT) of findings. According to these prestigious commentators, the carotid artery segments. No correlation was observed between lower is better era of LDL reduction had officially arrived. The fact that all-cause mortality did not differ between the twogroups, owing to an increase in noncardiovascular deaths among Conclusion ...
Igiena intima: igiena intima, produse naturale, produse igiena intima, aloe vera, baza de tratament, sistemul imunitar, efecte benefice, recomandari, plante apa, ulei plante, suplimente nutritive, utilizare a produsului,...
women-world este cel mai mare magazin online de lenjerie intima. Deschis in 2008, in acest moment importa direct si comercializeaza 9 branduri internationale de lenjerie intima si aproximativ 1500 de produse. Toate produsele comercializate sunt originale si acopera o gama larga de produse: babydoll, catsuit, corsete, bikini, sutiene, pijamale, seturi de lenjerie, seturi sexy pentru animatoare de club, accesorii de dormitor, manusi, halate sexy, rochii. Magazinul ofera clientilor posibilitatea de a filtra produsele in functie de culoarea/pretul/marimea/producatorul dorit.. ...
29 yrs old Male asked about Treatment for testies, 1 doctor answered this and 47 people found it useful. Get your query answered 24*7 only on | Practo Consult
Hi Ladies I don`t know if I`m clutching at straws here, I know I`m only 11 weeks and 4 days along but this morning when I was lying in bed just day dr
I have to do this question as a part of my homework but I have confuse. I m not sure about the first part of this question, and i m really confuse for
R.S.M.P., R.A.M.P. போட்டுக்கொண்டாலும் அவர்களுக்கு உரிய மருத்துவ கவுன்சிலில் பதிவு செய்திருக்க மாட்டார்கள். பதிவு செய்ய வேண்டுமென்றால் அவர்கள் பட்டம் பெற்றிருக்க வேண்டும். பக்கத்தில் உள்ள அச்சகத்திலோ (இப்போது கம்யூட்டர் செண்டரில் ) ஒரு காகிதத்தில் அச்சடித்து பிரேம் போட்டு மாட்டிக் கொண்டு தொழில் செய்பவர்களை காவல்துறை அவ்வப்போது கைது செய்து கொண்டேதான் இருக்கிறார்கள். I M Aவும் இது ...
Wspinaczka AlpinizmAlpinizm i wspinaczkaAlpinizm i wspinaczka Sklep - Modne Wspinaczka AlpinizmAlpinizm i wspinaczkaAlpinizm i wspinaczka w Portalu z Modą Damską i Męską - Wspinaczka AlpinizmAlpinizm i wspinaczkaAlpinizm i wspinaczka w Modea.pl
MaybeBlu Dreamwear Sklep - Oryginalne Produkty MaybeBlu Dreamwear w Portalu z Modą Damską i Męską - MaybeBlu Dreamwear w Modea.pl
It separates tunica intima from tunica media. It is readily visualized with light microscopy in sections of muscular arteries, ... elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of ... which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic ...
Tunica intima - Inner layer of blood vessel Pozzi, A; Yurchenco, PD; Iozzo, RV (January 2017). "The nature and biology of ...
The interior is lined with endothelial cells called tunica intima. The precise location of veins varies much more from person ... Microscopically, veins have a thick outer layer made of connective tissue, called the tunica externa or tunica adventitia. ... The middle layer of bands of smooth muscle are called tunica media and are, in general, much thinner than those of arteries, as ...
The elastic layer of the tunica intima is a fenestrated membrane. In surgery, a fenestration is a new opening made in a part of ...
It is characterized by fibrosis of the tunica intima and calcification of the tunica media. Arteriosclerosis Monckeberg's ...
A thin membrane of elastic fibers in the tunica intima run parallel to the vessel. The middle layer tunica media is the ... The middle layer is thicker in the arteries than it is in the veins: The inner layer, tunica intima, is the thinnest layer. It ... The tunica media is thicker in the arteries rather than the veins. The outer layer is the tunica adventitia and the thickest ... The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. ...
... the tunica intima, media, and adventitia. Atheroma and changes in the artery wall usually result in small aneurysms ( ... is always in the tunica intima, between the endothelium lining and the smooth muscle middle layer of the artery wall.[citation ... Regression analysis revealed that thickening of the mean intima-media complex more than 1.0 was predictive of significant CAD ... Promising results are found using carotid intima-media thickness scanning (CIMT can be measured by B-mode ultrasonography), B- ...
Most AAA are true aneurysms that involve all three layers (tunica intima, tunica media and tunica adventitia). The prevalence ...
The intima, tunica media, and tunica intima layers of these arteries remain intact and are generally unaffected. Thus, this ...
The vascular wall consists of several layers known as the tunica externa, tunica media, and tunica intima. The thickness of the ... which feed the tunica externa and tunica media outer layers of the aorta. The aortic arch contains baroreceptors and ... Within the tunica media, smooth muscle and the extracellular matrix are quantitatively the largest components of the aortic ...
... s form the fatty streaks of the plaques of atheroma in the tunica intima of arteries. Foam cells are not dangerous as ... In chronic hyperlipidemia, lipoproteins aggregate within the intima of blood vessels and become oxidized by the action of ...
... endothelial cells forming its tunica intima (inner layer), and pericytes forming its tunica adventitia (outer layer) ... The inner layer, Tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by ... The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. ... The outer layer is Tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It also ...
The most striking histopathological changes of the aneurysmatic aorta are seen in the tunica media and intima layers. These ... However, the degradation of the tunica media by means of a proteolytic process seems to be the basic pathophysiologic mechanism ... the tunica media must rely mostly on diffusion for nutrition, which makes it more susceptible to damage. Hemodynamics affect ...
Intimal hyperplasia - The thickening of the tunica intima of a blood vessel as a complication of a reconstruction procedure or ...
A dissecting aneurysm is when blood from the vessel lumen tracks between the two inner layers, the intima and the tunica media ...
... worn over an undergarment called a tunic or tunica intima (the Roman version of a slip). The stola was generally sleeveless but ...
... tunica media) layer almost to the inner (tunica intima) layer. In smaller vessels it penetrates only the outer layer. In the ... This means that it would take longer for any oxygen to diffuse through to the cells in the tunica adventitia and the tunica ... These small vessels serve to provide blood supply and nourishment for tunica adventitia and outer parts of tunica media of ... In the human descending aorta, vasa vasorum cease to supply the arterial tunica media with oxygenated blood at the level of the ...
... known as the tunica intima). Blood is then able to enter the space between the inner and outer layers of the vessel, causing ...
Stola Long, pleated dress, worn over an undergarment called a tunic or tunica intima, usually sleeveless but versions of it did ...
... endothelial cells forming its tunica intima (inner layer), and pericytes forming its tunica adventitia (outer layer) ... The inner layer, tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by ... A thin membrane of elastic fibers in the tunica intima run parallel to the vessel. ... The outer layer is the tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It also ...
... atheromatous plaques accumulate in the vascular tunica intima thereby narrowing blood vessel size and decreasing blood flow. In ...
The ensuing inflammation leads to formation of atheromatous plaques in the arterial tunica intima, a region of the vessel wall ... there is also smooth muscle proliferation and migration from the tunica media into the intima in response to cytokines secreted ... The fibrous plaque is also localized under the intima, within the wall of the artery resulting in thickening and expansion of ... Provost EB, Madhloum N, Int Panis L, De Boever P, Nawrot TS (2015). "Carotid intima-media thickness, a marker of subclinical ...
... refers to proliferation and migration of vascular smooth muscle cells primarily in the tunica intima, ... is used because the cells in the hyperplastic regions of the vascular wall have histological characteristics of both intima and ...
The tunica intima, which surrounds the lumen and is composed of simple squamal epithelial cells; the tunica media, composed of ... smooth cell muscles and elastic fibers; and, the tunica adventitia, composed of loose collagen fibers. Innervated by barometric ...
This is most likely due to a tear in the tunica intima (the inner layer), allowing blood to enter the tunica media, although ...
Platelet activation Susac's syndrome Tunica intima VE-cadherin Weibel-Palade body Angiocrine growth factors "Endothelium" at ... This state of endothelial cells promotes accumulation of lipids and lipoproteins in the intima, leading to atherosclerosis, and ... The lesions formed in the intima, and persistent inflammation lead to desquamation of endothelium, which disrupts the ...
... a layer of the tunica intima or tunica media), a dissection creates two lumens or passages within the vessel, the native or ...
... leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the ...
... meaning a layer of the blood vessel called tunica intima may thicken and the blood vessels will have a smaller opening ...
... tunica intima MeSH A10.272.497 - epidermis MeSH A10.272.497.500 - hair follicle MeSH A10.272.510 - epithelium, corneal MeSH ... tunica media MeSH A10.690.467.500 - myometrium MeSH A10.690.637 - myocardium MeSH A10.755.260 - ependyma MeSH A10.755.503 - ...
Tunica intima:最內層是與血管長軸平行排列的內皮細胞(endothelium),細胞之間以tight junction(zonula adherens)和gap junction(nexus)相接,前者構成穿越障礙,後者溝通周圍細胞。內皮下層 ... Tunica intima:由內皮細胞組
The vascular wall consists of several layers known as the tunica externa, tunica media, and tunica intima. The thickness of the ... which feed the tunica externa and tunica media outer layers of the aorta.[12] The aortic arch contains baroreceptors and ... Within the tunica media, smooth muscle and the extracellular matrix are quantitatively the largest components of the aortic ...
On the other hand, smooth muscle cells from the tunica media layer of the artery moved into the tunica intima, where the ... Saccular aneurysms tend to have a lack of tunica media and elastic lamina around its dilated location (congenital), with wall ... of sac made up of thickened hyalinized intima and adventitia.[7] In addition, some parts of the brain vasculature are ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
... atheromatous plaques accumulate in the vascular tunica intima thereby narrowing blood vessel size and decreasing blood flow. In ...
The interior is lined with endothelial cells called tunica intima. The precise location of veins varies much more from person ... called the tunica externa or tunica adventitia. There is a middle layer of bands of smooth muscle called tunica media, which ... called tunica adventitia or tunica externa; a middle layer of smooth muscle called the tunica media, and the inner layer lined ...
Tunica interna (edhe Intima), e clia ka edhe tri nënshtresa: *Endoteli. *Statum subendoteliale ...
inner coat (tunica intima). *fenestrated membrane. *middle coat (tunica media). Страница 499[редактиране , редактиране на кода] ...
A giant cell is seen on the right at the interface between the thickened intima and media. H&E stain ... These infiltrates erode the middle and inner layers of the arterial tunica media leading to conditions such as aneurysm and ...
Endothelium · Tunica intima · Tunica media · Tunica externa Vasa vasorum · Vasa nervorum Rete mirabile · Circulatory ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
主動脈剝離(英語:aortic dissection;法語:dissection aortique;德語:Aortendissektion),又譯為「主動脈夾層」或「心血管動脈撕裂」,是因為主動脈
A true aneurysm is one that involves all three layers of the wall of an artery (intima, media and adventitia). True aneurysms ... which is due to loss of the vasa vasorum in the tunica adventitia.[17] ...
When the endothelial cell in the tunica intima of an artery is stretched it is likely that the endothelial cell may signal ...
Tunica intima *Endothelium. *Internal elastic lamina. *Tunica media. *Tunica externa. *Vasa vasorum ...
The tunica intima, which surrounds the lumen and is composed of simple squamal epithelial cells; the tunica media, composed of ... smooth cell muscles and elastic fibers; and, the tunica adventitia, composed of loose collagen fibers.[3] Innervated by ...
... which is derect contact with the flow of blood is the Tunica Intima , commonly called the Intima .. This layer is made up of ... Tunica Media[সম্পাদনা]. Tunica media is also known as Tunica Adventita .. It is a made of smooth mucle cells and elastic tissue ... ৩) টিউনিকা ইন্টারনা (Tunica Interna) :- এই ভিতরের স্তরটি সরল অাবরনী কলা দিয়ে তৈরি ৷ ... ১) টিউনিকা এক্সটার্না (Tunica Externa) :- এটি একটি তন্তুম যোজক কলা দিয়ে তৈরি ৷ ...
... surrounding the tunica media Tunica intima, for short, is the innermost tunica (layer) of an artery or vein Tunica, a flowering ... Mississippi Tunica County, Mississippi Tunica Lake, Lee County, Arkansas and Tunica County, Mississippi Tunica Academy, a non- ... Tunica may refer to: The Latin word for tunic, a type of clothing typical in the ancient world Tunica (biology), a layer, ... a Native American group in the central Mississippi River Valley Tunica language, an isolate of the associated Tunica historic ...
The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is ... the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica externa). In dissection, the inner coat ( ... tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small ... The structure of the tunica intima depends on the blood vessel type. Elastic arteries - A single layer of epithelial cells and ...
What does tunica-intima mean? The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported ... Tunica-intima Sentence Examples. *. Can you identify the endothelium, and underlying connective tissue of the tunica intima ... B. Venous valves are folds of tissue formed from the endothelial lining of the tunica intima. ...
... tunica intima explanation free. What is tunica intima? Meaning of tunica intima medical term. What does tunica intima mean? ... Looking for online definition of tunica intima in the Medical Dictionary? ... Related to tunica intima: endothelium, atherosclerosis, tunica adventitia, tunica media, tunica externa ... Tunica intima , definition of tunica intima by Medical dictionary https://medical-dictionary.thefreedictionary.com/tunica+ ...
Tunica intima-media thickness and coronary disease. Mosti G., Iabichella M. L., Picerni P., Fontanini F. ...
... and the intima. 2. Sketch the artery below that ... Label on your diagram the tunica media, the endothelium, the ... Label on your diagram the tunica media, the endothelium, the lumen, and the intima. 2. Sketch the artery below that ... Label on your diagram the tunica media, the endotherlium, the lumen, and the atheroma.... View Full Document ...
... The innermost coat of blood vessels, consisting of a thin lining of endothelial cells longitudinally oriented ...
Tunica intima:This name refers to the inner layer of a blood vessel. It mostly contains elastic membranes and tissues and can ... Tunica media: This is the middle later of a blood vessel. Elastin and muscle fibers make up the tunica media. The amount of ... Tunica adventitia: The outer layer of a blood vessel consists of collagen and elastin and is known as the tunica adventitia. ... For example, elastic arteries contain few muscle fibers in their tunica media. ...
Tunica Intima/Tunica Interna •Tunica Media •Tunica Adventitia/Tunica ExternaLesson 9 in our Cardiovascular System (Heart and ...
The effect of AND on histological sections of aorta in atherosclerotic rabbits (H&E). TI; tunica intima; TM; tunica media; ... with very little deposits observed in the intima tunica and medica tunica region, and no cholesterol deposit was seen in the ... the histology results showed that there are thick plaques and lipids accumulation in the tunica intima regions of the aorta. ... The intima was irregularly thickened and multilaminated. The internal elastic lamina was also thickened. Fatty streaks were ...
The tunica intima of a deep vein usually has a one-way valve to prevent blood from flowing backward. Nearby muscles also ... The tunica intima of a superficial vein can also have a one-way valve. However, without a nearby muscle for compression, they ... Tunica intima. This is the innermost layer. Its a single layer of endothelium cells and some connective tissue. This layer ... Tunica media. The tunica media is the middle layer. Its thin and contains a large amount of collagen. Collagen is one of the ...
Tunica Intima. *Wounds and Injuries. *adverse effects. *cytology. *drug effects. *etiology. *genetics ...
To begin with, it must be noted that the normal coronary intima is not a single-layer endothelium covering a thin acellular ... followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation ... Why does arterial tunica intima become neovascularized in the first place?. Early during life the tunica intima of human ... Therefore, although the coronary tunica intima is a multi-layered cellular compartment equal to or thicker than the tunica ...
... tunica intima), the middle layer (tunica media), and the outermost layer (tunica adventitia or externa); all encapsulated in ... The tunica intima of CAs. The intima consists of a lining layer of longitudinally oriented endothelial cells that cover the ... Pathogenesis of atherosclerosis in the tunica intima, media, and adventitia of coronary arteries: An updated review * ... The view that the tunica intima normally consists of a single layer of endothelial cells attached to the subendothelial layer ...
... endothelial cells forming its tunica intima (inner layer), and pericytes forming its tunica adventitia (outer layer) ... The inner layer, Tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by ... The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. ... The outer layer is Tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It also ...
Tunica Intima / drug effects* * Tunica Intima / enzymology * Tunica Intima / metabolism * Tunica Intima / pathology ...
It separates tunica intima from tunica media. It is readily visualized with light microscopy in sections of muscular arteries, ... elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of ... which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic ...
Blood vessels consist of three layers:the intima, media, and adventitia. *Tunica intima(the thinnest single layer): It is ... Tunica media(the thickest layer in arteries) :It is composed of elastin, collagen, and smooth muscle, largely determines the ... Tunica adventitia:It consists mainly of connective tissue. It is mainly composed of collagen and, in arteries, is supported by ...
Tunica Intima/Tunica Interna. •Tunica Media. •Tunica Adventitia/Tunica Externa. Lesson 9 in our Cardiovascular System (Heart ...
... tunica media. - Large veins have diameters > 10mm, thicker tunica intima, no prominent tunica media and a well-developed tunica ... Tunica intima:. - Next to the lumen. - Contains the endothelium, a subendothelial layer and internal, discontinuous elastic ... Small and medium sized veins have well developed adventitia and thin tunica intima + ... Except the tunica media has 40 layers of smooth muscle cells (rather than 40-70 fenestrated elastic lamellae) which are ...
Tunica intima. No smooth muscle, elastic tissue.. Tight junctions. important role in the diameter of blood vessel by releasing ...
Tunica Media. Smooth inner layer of veins and arteries. Tunica Intima. Most inner layer of veins and arteries made of a single ... Squamous Epithelia cells in the tunica intima. Precapillary spincters. Guard entrances to the capillaries and determine how ... Tunica Externa. Outer layer of veins and arteries made of connective fibers so they do not burst under pressure. ...
Loose tunica media made of individual smooth muscle cells that wrap around the tunica intima. ... Tunica media made of____muscle and ____connect tissue. Smooth, elastic. Tunica media helps maintain BP during _____. Diastole ( ... Tunica externa made of___ ___ fibrous connective tissue. Dense irregular. Dense irregular fibrous connective tissue provides ... Tunica intima is ____ with the Endocardium. continuous. ____prevents clotting. Smoothness. Tunica intima produces____. Nitrous ...
Tunica Intima / ultrasonography. Chemical. Reg. No./Substance: 9002-84-0/Polytetrafluoroethylene From MEDLINE®/PubMed®, a ...
... and intima media thickness (IMT) in the carotid artery correlate with the extent of coronary artery ... Tunica Intima / ultrasonography. Tunica Media / ultrasonography. Vasodilation*. Vasodilator Agents / diagnostic use. Chemical. ... Comparative predictive and diagnostic value of flow-mediated vasodilation in the brachial artery and intima media thickness of ... and intima media thickness (IMT) in the carotid artery correlate with the extent of coronary artery disease (CAD), it is not ...
tunica advetitia, tunica media,tunica intima *from outer to inner.. Are the veins in the valve? ...
... inflammation involving the tunica intima and media but not spreading through the adventitia; score 1, inflammation localized to ... the tunica intima; and score 0, no inflammatory cell infiltration in the vascular wall. A section with severe inflammation was ...
... Artery wall Transverse section through a small artery and vein of the mucous membrane of the ... It lies between the tunica intima on the inside and the tunica adventitia on the outside. ... The tunica media (or just media) is the middle layer of an artery or vein.[1] ... The middle coat (tunica media) is distinguished from the inner by its color and by the transverse arrangement of its fibers. ...
of a vessel wall (tunica intima and tunica adventitia). in a decellularized rat lung. ...
What is the disorder of the arteries that refers to the gradual thickening of the tunica intima?. ... what is a thickened area of the tunica intima along an artery called?. ... outside the endothelium of the blood vessel, the rest of the intima consists of connective tissue. What is the name of this ...
  • The outer layer of a blood vessel consists of collagen and elastin and is known as the tunica adventitia. (medicalnewstoday.com)
  • During the development of atherosclerosis, the microvessels from the tunica adventitia or from the lumen may penetrate thickened media to provide nutrition and oxygenation. (bjbms.org)
  • Milutinović A, Šuput D, Zorc-Pleskovič R. Pathogenesis of atherosclerosis in the tunica intima, media, and adventitia of coronary arteries: An updated review. (bjbms.org)
  • The outer layer is Tunica adventitia and the thickest layer in veins. (wikipedia.org)
  • Tunica intima, Tunica media and Tunica adventitia. (brainscape.com)
  • It lies between the tunica intima on the inside and the tunica adventitia on the outside. (bionity.com)
  • which separates the tunica media from the tunica adventitia. (coursera.org)
  • Tunica adventitia (tunica externa) is the outer layer of a blood vessel, including arteries and veins. (healthline.com)
  • The external tunica adventitia, mainly composed of connective tissue, is just visible upper left. (sciencephoto.com)
  • In addition, the tunica media of veins is much thinner than in arteries, and the adventitia is the thickest layer. (une.edu)
  • All arteries comprise three layers: the tunica intima, the tunica media and the tunica adventitia. (reference.com)
  • The tunica adventitia of the arteries are much thicker than that of the veins so that the artery can withstand the high pressure blood. (healthhype.com)
  • Arteries and arterioles are stratified structurally into three layers: tunica intima, tunica media, and tunica externa (also called the tunica adventitia). (crossfit.com)
  • kPa in the tunica adventitia, and from 79.3±7.2 to 146.6±28.8. (ibecbarcelona.eu)
  • Though cross talk between the coordinated inflammatory foci in the intima and the adventitia seems implicit, the mechanism(s) underlying their communication is unclear. (nih.gov)
  • Tunica Adventitia - the strong outer covering of arteries and veins. (thoughtco.com)
  • Strictly intravascular approaches for the treatment of postangioplasty restenosis are effective in the intima and the inner parts of the media but may be insufficient to control redundant pathways in the more outer parts of the media and the adventitia. (nih.gov)
  • Pseudoaneurysms are the result of the rupture of all three layers of the artery: the tunica intima, media, and adventitia. (lww.com)
  • 13,14 Sites of inflammation relevant to disease biology may not only include the atherosclerotic intima and media but also the tunica adventitia. (ahajournals.org)
  • The three layers of a blood vessel are an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica externa). (wikipedia.org)
  • Tunica externa. (healthline.com)
  • The tunica externa also contains tiny blood vessels called vasa vasorum that supply blood to the walls of your veins. (healthline.com)
  • Tunica externa - composed of connective tissue - collagen and elastic fibers. (flashcardmachine.com)
  • The tunica externa (exterior layer) is made up of connective tissue with scattered smooth muscle cells. (crossfit.com)
  • The tunica media and externa are less extensive in veins. (crossfit.com)
  • Label on your diagram the tunica media, the endothelium, the lumen, and the intima. (coursehero.com)
  • The pale, innermost tunica intima surrounds the lumen (white). (sciencephoto.com)
  • The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. (wikipedia.org)
  • Comparative predictive and diagnostic value of flow-mediated vasodilation in the brachial artery and intima media thickness of the carotid artery for assessment of coronary artery disease severity. (biomedsearch.com)
  • BACKGROUND: While recent reports suggest that both flow-mediated vasodilation (FMD) in the brachial artery (BA), endothelium-dependent vasodilatation, and intima media thickness (IMT) in the carotid artery correlate with the extent of coronary artery disease (CAD), it is not clear which modality is a better predictor for CAD severity and whether either of these modalities are superior to conventional ST-segment depression in exercise stress electrocardiogram (ECG). (biomedsearch.com)
  • The tunica media (or just media ) is the middle layer of an artery or vein . (bionity.com)
  • This study, therefore, aimed at correlating its intima - media thickness with morphological features of left coronary artery in a black Kenyan population. (omicsonline.org)
  • Conclusion: The intima - media thickness of left anterior descending artery is influenced by length, bifurcation angle and terminal branching pattern of left coronary artery, and is higher in males than in females. (omicsonline.org)
  • Intima-media thickness of the carotid artery (CIMT) and its increase is associated with several cardiovascular risk factors and manifest cardiovascular diseases. (smw.ch)
  • Carotid intima-media thickness (CIMT), recorded with B-mode sonography, is an important marker to quantify atherosclerotic burden in the common carotid artery (CCA). (smw.ch)
  • The three layers of the artery wall are the innermost tunica intima, the outermost tunica admentita and the tunica media in between them. (reference.com)
  • Notice the large constituent of elastic fibers in the tunica media (middle layer) as compared to the muscular artery on the previous slide. (une.edu)
  • Excision of the thickened, atheromatous tunica intima of a carotid artery . (citizendium.org)
  • Mechanisms of dissection: As the layer which makes up the vessel lining, the tunica intima is more susceptible to tearing [ 32 ] and as such is the typical site of the initial defect which initiates a vertebral artery dissection (VAD). (chiro.org)
  • The endothelium of the artery is a thin cell layer which lines the innermost layer of cells, known as the tunica intima. (innerbody.com)
  • The tunica intima has an endothelium of flattened endothelial cells. (yourdictionary.com)
  • B. Venous valves are folds of tissue formed from the endothelial lining of the tunica intima. (yourdictionary.com)
  • An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation. (biomedcentral.com)
  • The view that the tunica intima normally consists of a single layer of endothelial cells attached to the subendothelial layer and internal elastic membrane has been questioned in recent years. (bjbms.org)
  • the inner lining called the tunica intima (commonly called the intima), which is made up of endothelial cells. (medpagetoday.com)
  • These vessels are very thin to enable gas exchange - it is usually just a single endothelial cell layer in thickness (similar to the intima), lacks a media layer and there may be some supporting connective tissue. (healthhype.com)
  • The innermost layer, the tunica intima, is composed of endothelial cells (small cells) and elastic connective tissue elements. (crossfit.com)
  • the inner lining (which is in contact with the blood) called the tunica intima (commonly called the intima ), which is made up of endothelial cells- thin smooth cell which reduce friction through the blood vessels. (celebritydiagnosis.com)
  • Can you identify the endothelium, and underlying connective tissue of the tunica intima layer in this photograph? (yourdictionary.com)
  • To begin with, it must be noted that the normal coronary intima is not a single-layer endothelium covering a thin acellular compartment, as claimed in most publications, but always appears as a multi-layer cellular compartment, or diffuse intimal thickening (DIT), in which cells are arranged in many layers. (biomedcentral.com)
  • robert furchgott discovered the importance of the endothelium in controlling vertebrate vascular resistance by chance (reviewed in Ref. 16 ), and in the ensuing years it has become apparent that the intima of blood vessels plays a pivotal role in the control of vascular homeostasis (e.g. (physiology.org)
  • The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels. (wikipedia.org)
  • In elastic arteries such as the aorta, which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic lamina is approximately the same thickness as the other elastic laminae that are normally present. (wikipedia.org)
  • Lamina, which separates the tunica intima from the tunica media. (coursera.org)
  • between Tunica intima and Tunica media: internal elastic lamina. (smw.ch)
  • The intima, the innermost layer (basal lamina) provides a smooth surface for blood to flow across. (springer.com)
  • The veins also lack the elastic internal lamina that lies between the intima and media in the arteries. (healthhype.com)
  • Most fibromas developed near blood vessels or from conjunctive tissue cells in the tunica intima. (thefreedictionary.com)
  • the tunica adventia, the outer layer of the blood vessel made of a more fibrous material. (medpagetoday.com)
  • The intima is separated from the media by the internal elastic membrane, which is composed of fenestrated layer of elastic fibers. (bjbms.org)
  • The structure of the tunica intima depends on the blood vessel type. (wikipedia.org)
  • tunica exter´na an outer coat, such as the fibroelastic coat of a blood vessel. (thefreedictionary.com)
  • tunica me´dia the muscular middle coat of a blood vessel. (thefreedictionary.com)
  • The tunica media may (especially in arteries) be rich in vascular smooth muscle , which controls the caliber of the vessel. (wikipedia.org)
  • The inner layer of the blood vessel wall is called tunica intima. (healthline.com)
  • The invention relates to a blood vessel treating assembly comprising: an artificial blood vessel inner layer such as an artificial tunica-intima or the like for replacing a section of blood vessel inner layer previously removed from a blood vessel and/or for covering a predetermined length of damaged. (google.com.au)
  • 3. An artificial blood vessel inner layer such as an artificial tunica-intima or the like, comprising at least one tube-like section of synthetic material, and diameter arranging means for increasing and/or decreasing the diameter of the tube-like section. (google.com.au)
  • A thin membrane of elastic fibers in the tunica intima run parallel to the vessel. (wikipedia.org)
  • As blood accumulates within the separated vessel layers, a thrombus is created with further deformation of the intima and obstruction of blood flow. (chiro.org)
  • The middle layer of the walls of arteries and veins is called the tunica media. (healthline.com)
  • Tunica Intima - the inner layer of arteries and veins. (thoughtco.com)
  • Background: Intima-Media thickness is an acknowledged surrogate marker for predicting and profiling of atherosclerotic cardiovascular disease. (omicsonline.org)
  • Results: The mean intima - media thickness was 0.332 mm. (omicsonline.org)
  • Intima-Media Thickness (IMT) is a reliable sensitive marker of subclinical atherosclerosis [ 1 - 3 ] and an independent predictor of cardiovascular events and target organ damage [ 3 , 4 ]. (omicsonline.org)
  • 31 ] Three layers from inside to out (tunica intima, tunica media, tunica adventia) comprise the cervical arteries. (chiro.org)
  • Neovascularization of coronary tunica intima (DIT) is the cause of coronary atherosclerosis. (biomedcentral.com)
  • The multilayering of intima is classically considered to be an important stage in the development of atherosclerosis, but in fact atherosclerotic plaques develop only focally due to the interplay of various processes that involve the resident and invading inflammatory cells. (bjbms.org)
  • Atherosclerosis involves a macrophage-rich inflammation in the aortic intima. (nih.gov)
  • The tunica media is thicker in the arteries rather than the veins. (wikipedia.org)
  • The tunica media consists of multiple layers of smooth muscle cells that produce the extracellular matrix, and this layer normally does not contain microvessels. (bjbms.org)
  • Arteries have a thicker more regular tunica media. (une.edu)
  • tunica vasculo´sa a vascular coat, or a layer well supplied with blood vessels. (thefreedictionary.com)
  • The tunica intima of a deep vein usually has a one-way valve to prevent blood from flowing backward. (healthline.com)
  • In aortic dissection, damage to the intima layer allows blood to dissect its way into the media layer. (medpagetoday.com)
  • In some veins, the tunica intima layer also contains valves to keep blood flowing in a single direction. (thoughtco.com)
  • Damage to the intima of blood vessels, hypercoagulation, and decreased blood flow are contributory factors in the formation of thrombus within the vessels. (medscape.com)
  • Damage to the tunica intima is the predominant factor in septic sinus thrombosis because the inflammatory process initiates fibrin formation and aggregation of blood platelets. (medscape.com)
  • tunica muscula´ris the muscular coat or layer surrounding the tela submucosa in most portions of the digestive, respiratory, urinary, and genital tracts. (thefreedictionary.com)
  • The tunica medica, which is the very muscular middle layer in arteries, is thinner and less muscular in veins. (healthhype.com)
  • Further damage may be wrought by pulsatile pressure to the muscular layer, causing further splitting of the intima and media during a dissection. (chiro.org)
  • The tunica media mainly consists of smooth muscle cells in a spiral arrangement. (coursera.org)
  • The tunica media (middle layer) consists mostly of smooth muscle cells. (crossfit.com)
  • The structure of intima changes with age and it becomes multilayered due to migration of smooth muscle cells from the media to intima. (bjbms.org)
  • At this stage, the migration and proliferation of smooth muscle cells do not cause pathological changes in the intima. (bjbms.org)
  • The middle layer, the thick tunica media (dark pink), is mainly composed of elastic and smooth muscle fibres. (sciencephoto.com)
  • Lipid accumulation in thickened intima culminated in type IV whereas the highest collagen deposition was found in Type V lesions. (ahajournals.org)
  • The inner layer, Tunica intima , is the thinnest layer. (wikipedia.org)
  • It is characterized by fibrosis of the tunica intima and calcification of the tunica media. (wikipedia.org)
  • The tunica media is the middle layer. (healthline.com)
  • The middle coat (tunica media) is distinguished from the inner by its color and by the transverse arrangement of its fibers. (bionity.com)
  • tunica albugi´nea a dense white fibrous sheath that encloses a part or organ, such as the testicle or ovary. (thefreedictionary.com)
  • The tunica intima of a superficial vein can also have a one-way valve. (healthline.com)