Tunica Intima
Tunica Media
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
Penile Induration
A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
Testicular Hydrocele
Penis
The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
Elastic Tissue
Penile Implantation
Arteriosclerosis
Penile Prosthesis
Impotence, Vasculogenic
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. (1/3315)
1. We examined whether endogenous inhibitors of NO synthesis are involved in the augmentation of intimal hyperplasia in rabbits with hyperglycaemia induced by alloxan. 2. Four weeks after the endothelial denudation of carotid artery which had been performed 12 weeks after alloxan, the intimal hyperplasia was greatly augmented with hyperglycaemia. The degree of hyperplasia was assessed using three different parameters of histopathological findings as well as changes in luminal area and intima: media ratio. 3. There were positive and significant correlations between intima:media ratio, plasma glucose, and concentrations of N(G)-monomethyl-L-arginine (L-NMMA) and N(G), N(G)-dimethyl-L-arginine (ADMA) in endothelial cells, that is, the intima:media ratio became greater as plasma glucose and endothelial L-NMMA and ADMA were increased. Furthermore, endothelial L-NMMA and ADMA were increased in proportion to the increase in plasma glucose. 4. In contrast, there were inverse and significant correlations between cyclic GMP production by carotid artery strips with endothelium and plasma glucose, between cyclic GMP production and endothelial L-NMMA and ADMA, and between the intima:media ratio and cyclic GMP production. 5. Exogenously applied L-NMMA and ADMA inhibited cyclic GMP production in a concentration-dependent manner. IC50 values were determined to be 12.1 microM for the former and 26.2 microM for the latter. The cyclic GMP production was abolished after the deliberate removal of endothelium from the artery strips. 6. These results suggest that the augmentation of intimal hyperplasia with hyperglycaemia is closely related to increased accumulation of L-NMMA and ADMA with hyperglycaemia, which would result in an accelerated reduction in NO production/release by endothelial cells. (+info)Studies on structural changes of the carotid arteries and the heart in asymptomatic renal transplant recipients. (2/3315)
BACKGROUND: The present study was designed to characterize early structural changes of large arteries in renal transplant recipients with no clinical evidence of cardiovascular disease and normal blood pressure values, and to analyse the relationship between arterial alterations and those of the heart. METHODS: Intima media thickness and atherosclerotic plaques of the carotid arteries as well as left ventricular geometry and function were examined in 35 asymtomatic renal transplant recipients and 29 age- and sex-matched healthy controls by high resolution B-mode ultrasound and by echocardiography. RESULTS: Intima-media thickness of the carotid arteries was significantly higher in renal transplant recipients (1.21+/-0.08 mm) than in healthy controls (0.74+/-0.04 mm) (P<0.001). Atherosclerotic plaques were found in the majority of renal transplant recipients (71% vs 14% in healthy controls, P<0.001). Left ventricular mass index was significantly increased in the group of renal transplant recipients (264+/-13 g, 146+/-7 g/m2) when compared with healthy controls (155+/-8 g, 83+/-4 g/m2) (P<0.001). Multiple regression analysis in renal transplant recipients showed that intima media thickness of the carotid arteries was significantly related to left ventricular mass index (P<0.02), but not to age, blood pressure, body mass index, serum creatinine, cholesterol and lipoprotein (a) levels. In the group of healthy controls, intima-media thickness of the carotid artery was related to age (P<0.002), but not to left ventricular mass index or the other independent variables. CONCLUSIONS: The present study documents pronounced intima-media thickening in asymptomatic renal transplant recipients. Atherosclerotic lesions are present in most renal transplant recipients with no clinical evidence of cardiovascular disease. We observed a parallelism between arterial wall thickening and left ventricular hypertrophy, although blood pressure levels were normal during haemodialysis therapy and after renal transplantation. (+info)Arterial damage induced by cryopreservation is irreversible following organ culture. (3/3315)
OBJECTIVES: The aim of the present study was to investigate the changes which occur to the arterial wall following cryopreservation and thawing and to determine whether these changes are reversible after a week of culture in an organ bath. MATERIALS AND METHODS: Rat iliac arterial segments were cryopreserved. Once thawed, the arterial segments were cultured for a period of 0, 1, 2, 4 or 7 days. Freshly isolated rat iliac vessels cultured for 7 days served as the control group. Evaluation was made of ultrastructural changes, the expression of metalloproteinase activity (MMP-1, MMP-3 and MMP-9) and the apoptotic state of cells. RESULTS: The freezing-thawing process induced damage to the arterial segments compared to fresh control vessels. After 1 week of culture, arteries showed a high degree of tissue degeneration. Only a few individual endothelial cells remained on the luminal surface. There was a gradual increase in the proportion of apoptotic cells. The sequential expression of MMP-1 during the first 2 days and subsequent expression of MMP-3 and MMP-9 were of most significance. CONCLUSIONS: Cryopreservation induced damage to the vessels which could not be reversed by organ culture. The changes observed in the expression of metalloproteinases may be indicative of the degenerative process which occurs in the extracellular matrix. (+info)Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. (4/3315)
The perivascular implantation of tissue-engineered endothelial cells around injured arteries offers an opportunity to study fundamental vascular physiology as well as restore and improve tissue function. Cell source is an important issue because the ability to implant either xenogeneic or allogeneic cells would greatly enhance the clinical applications of tissue-engineered grafts. We investigated the biological and immunological responses to endothelial cell xenografts and allografts in pigs 4 weeks after angioplasty of the carotid arteries. Porcine or bovine aortic endothelial cells were cultured within Gelfoam matrices and implanted in the perivascular space of 42 injured arteries. Both porcine and bovine endothelial cell grafts reduced the restenosis index compared with control by 54% and 46%, respectively. Perivascular heparin release devices, formulated to release heparin at twice the rate of release of heparan sulfate proteoglycan from endothelial cell implants, produced no significant reduction in the restenosis index. Endothelial cell implants also reduced occlusive thrombosis compared with control and heparin release devices. Host immune responses to endothelial implants were investigated by immunohistochemical examination of explanted devices and by immunocytochemistry of serum samples. The bovine cell grafts displayed infiltration of leukocytes, consisting primarily of lymphocytes, and caused an increase in antibodies detected in serum samples. Reduced cellular infiltration and no humoral response were detected in animals that received allografts. Despite the difference in immune response, the biological effects of xenografts or allografts did not differ significantly. (+info)Cross-sectional and 4-year longitudinal associations between brachial pulse pressure and common carotid intima-media thickness in a general population. The EVA study. (5/3315)
BACKGROUND AND PURPOSE: The cross-sectional and 4-year longitudinal associations between brachial pulse pressure (PP) and ultrasound measurements of common carotid intima-media thickness (CCA-IMT) were assessed. METHODS: A population of 957 volunteers aged 59 to 71 years was recruited from the electoral rolls of the city of Nantes (western France) and reexamined 4 years later. Longitudinal changes in PP and CCA-IMT were computed as the difference between 4-year follow-up and baseline values. RESULTS: Baseline CCA-IMT and PP were positively associated in both age- and sex-adjusted analysis (partial correlation coefficient=0.20, P<0.001) and in multivariate analysis adjusted for traditional cardiovascular risk factors and mean blood pressure (partial correlation coefficient=0.18, P<0.001). In longitudinal analysis, baseline PP was associated with the change in 4-year CCA-IMT (partial correlation coefficient=0.11, P<0.001), and baseline CCA-IMT was a predictor of the 4-year change in PP (partial correlation coefficient=0.10, 0.001+info)
Prevention of neointimal formation by a serine protease inhibitor, FUT-175, after carotid balloon injury in rats. (6/3315)
BACKGROUND AND PURPOSE: In vivo and vitro studies revealed the activation of thrombin and the complement system in vascular lesion formation during the process of atherosclerosis, along with pathological proliferation of smooth muscle cells. We examined the effect of the synthetic serine protease inhibitor FUT-175 (developed as a potent inhibitor of thrombin and the complement system) on vascular lesions using balloon dilatation-induced neointimal formation in the carotid artery of rats. METHODS: Sprague-Dawley (SD) rats underwent balloon dilatation injury of the left carotid artery to induce neointimal formation. Three groups of these rats (n=8, each) were treated with daily intraperitoneal injections of 1 of the following doses of FUT-175: 0.5, 1.0, or 2.0 mg/d in 1 mL of saline for 7 consecutive days. The control group (n=8) was similarly treated with 1 mL of saline for 7 days. The injections were started immediately after balloon injury. Two weeks after the injury, the left carotid arteries were perfusion-fixed, and the areas of the neointimal and medial layer were analyzed under a microscope. RESULTS: A morphometric analysis revealed that there were significant differences in the intima-media ratio between the 4 groups treated with vehicle (saline) or a low, medium, or high dose of FUT-175 (1.45+/-0.11, 1.08+/-0.06, 0.71+/-0.04, or 0.32+/-0.04, respectively). This suppression was achieved in a dose-dependent manner by the administration of FUT-175 after balloon injury. In the histological study, it was demonstrated that FUT-175 suppresses the production of platelet-derived growth factor (PDGF)-BB in the neointima and the medial smooth muscle cell layer. CONCLUSIONS: After balloon injury activated proteases that were inhibited by FUT-175 were demonstrated to have an essential role in the development of the pathological thickening of the arterial wall. (+info)Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. (7/3315)
BACKGROUND: Exposure to risk factors such as hypertension or hypercholesterolemia decreases the bioavailability of endothelium-derived nitric oxide (NO) and impairs endothelium-dependent vasodilation. Recently, a circulating endogenous NO synthase inhibitor, asymmetric dimethylarginine (ADMA), has been detected in human plasma. The purpose of this study was to examine the relationship between plasma ADMA and atherosclerosis in humans. METHODS AND RESULTS: Subjects (n=116; age, 52+/-1 years; male:female ratio, 100:16) underwent a complete history and physical examination, determination of serum chemistries and ADMA levels, and duplex scanning of the carotid arteries. These individuals had no symptoms of coronary or peripheral artery disease and were taking no medications. Univariate and multivariate analyses revealed that plasma levels of ADMA were positively correlated with age (P<0.0001), mean arterial pressure (P<0.0001), and Sigma glucose (an index of glucose tolerance) (P=0.0006). Most intriguingly, stepwise regression analysis revealed that plasma ADMA levels were significantly correlated to the intima-media thickness of the carotid artery (as measured by high-resolution ultrasonography). CONCLUSIONS: This study reveals that plasma ADMA levels are positively correlated with risk factors for atherosclerosis. Furthermore, plasma ADMA level is significantly correlated with carotid intima-media thickness. Our results suggest that this endogenous antagonist of NO synthase may be a marker of atherosclerosis. (+info)Immunohistochemical analysis of arterial wall cellular infiltration in Buerger's disease (endarteritis obliterans). (8/3315)
PURPOSE: The diagnosis of Buerger's disease has depended on clinical symptoms and angiographic findings, whereas pathologic findings are considered to be of secondary importance. Arteries from patients with Buerger's tissue were analyzed histologically, including immunophenotyping of the infiltrating cells, to elucidate the nature of Buerger's disease as a vasculitis. METHODS: Thirty-three specimens from nine patients, in whom Buerger's disease was diagnosed on the basis of our clinical and angiographic criteria between 1980 and 1995 at Nagoya University Hospital, were studied. Immunohistochemical studies were performed on paraffin-embedded tissue with a labeled streptoavidin-biotin method. RESULTS: The general architecture of vessel walls was well preserved regardless of the stage of disease, and cell infiltration was observed mainly in the thrombus and the intima. Among infiltrating cells, CD3(+) T cells greatly outnumbered CD20(+) B cells. CD68(+) macrophages or S-100(+) dendritic cells were detected, especially in the intima during acute and subacute stages. All cases except one showed infiltration by the human leukocyte antigen-D region (HLA-DR) antigen-bearing macrophages and dendritic cells in the intima. Immunoglobulins G, A, and M (IgG, IgA, IgM) and complement factors 3d and 4c (C3d, C4c) were deposited along the internal elastic lamina. CONCLUSION: Buerger's disease is strictly an endarteritis that is introduced by T-cell mediated cellular immunity and by B-cell mediated humoral immunity associated with activation of macrophages or dendritic cells in the intima. (+info)Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes...
Tunica intima - Wikipedia
Association of the Cardioankle Vascular Index and Ankle-Brachial Index with Carotid Artery Intima Media Thickness in...
Carotid Intima-media thickness in childhood and adolescent obesit...
Intima-media thickness - Wikipedia
Most recent papers with the keyword Coronary calcification | Read by QxMD
Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection - Full Text View - ClinicalTrials.gov
Cardiovascular Health Profile (MG069A) - MediFast HK Ltd.
主動脈剝離 - 維基百科,自由的百科全書
Effects of Oral Prednisone After Stenting in a Rabbit Model of Established Atherosclerosis | JACC: Journal of the American...
Artery, TEM - Stock Image C033/7106 - Science Photo Library
Overexpression of the P2Y2 Purinoceptor in Intimal Lesions of the Rat Aorta | Arteriosclerosis, Thrombosis, and Vascular Biology
Cele mai bune 10 produse pentru igiena intima - Amelie.ro
Intimal re-layering technique for type A acute aortic dissection-reconstructing the intimal layer continuity to induce...
Exploring the similarities between neointimal formation after vascular injury and tumour growth at University of Bristol on...
Herbal Care Gel Calmant Pentru Igiena Intima Cu Extract De Albastrele Si Acid Lactic 330ml (45 - FrumuseteSiSanatate.ro
Best 25+ Crioterapia para adelgazar ideas on Pinterest | Consejos para dieta limpia, Cuerpo sexy and Higiene intima femenina
Activities : Health and Medicine Division
The triple line pattern on carotid intima media thickness imaging and | VHRM
Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers...
Thapsigargin inhibits smooth muscle cell proliferation and intima formation in human saphenous vein<...
Abstract 1186: Arterial Wall Properties and Endothelial Function in HIV Infected Patients | Circulation
Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British...
eCite - Continuous and dichotomous metabolic syndrome definitions in youth predict adult type 2 diabetes and carotid artery...
Kronos Early Estrogen Prevention Study (KEEPS) - Full Text View - ClinicalTrials.gov
The Cardiovascular System: Blood Vessels : Anatomy & Physiology
G-Protein-Coupled Receptor Kinase Interacting Protein-1 Mediates Intima Formation by Regulating Vascular Smooth Muscle...
Carotid Intima Media Thickness: A Measurement for Cardiovascular Risk and its Association with Hormone Deficiencies -...
AB0293 Carotid Intima Media Thickness and Interleukin -17 Level in Rheumatoid Arthritis Patients | Annals of the Rheumatic...
Internal elastic membrane | Article about internal elastic membrane by The Free Dictionary
Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs<...
Vascular smooth muscle cells (VSMCs) proliferation and migration, that are central | Ubiquitin-Mediated Proteolysis of the...
Indmedica - Indian Journal for the Practising Doctor
Plasminogen Is a Critical Determinant of Vascular Remodeling in Mice | Circulation Research
Matrix Metalloproteinase-9 Is Necessary for the Regulation of Smooth Muscle Cell Replication and Migration After Arterial...
Intima â Media Thickness of Left Anterior Descending Coronary Artery in a
Black Kenyan Population: Correlation with...
Inhibitory actions of several natural products on proliferation of rat vascular smooth muscle cells induced by Hsp60 from...
Non-Invasive Diagnostic Testing | American Family Medical
Abstract 1161: PKA-activated p85alpha Prevents Neointimal Hyperplasia after Balloon Endothelial Denudation without Impairing...
Patent US5914316 - Method of inhibiting intimal hyperplasia - Google Patents
US5914316A - Method of inhibiting intimal hyperplasia - Google Patents
CASE-CONTROL ERWINIA INDIVIDUALS CARRYING THE MOBILE SNP/CMM\RT-PRC GENE LOAD « FAROUCHE OMBRÉ
Journal05-03a.cdr
Igiena intima
Promotii online: Lenjerie intima: babydoll, body, ciorapi
Treatment For Testies - Sir, I M Having A | Practo Consult
Could it be possible??
Probability-collisions
கிராமங்களுக்குச் செல்ல மருத்துவர்களுக்கு என்ன பயம்...
Wspinaczka AlpinizmAlpinizm i wspinaczkaAlpinizm i wspinaczka - Sklep
MaybeBlu Dreamwear Sklep
Tunica intima
The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is ... the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica externa). In dissection, the inner coat ( ... tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small ... The structure of the tunica intima depends on the blood vessel type. Elastic arteries - A single layer of Endothelial and a ...
Internal elastic lamina
It separates tunica intima from tunica media. It is readily visualized with light microscopy in sections of muscular arteries, ... elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of ... which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic ...
Vein
The interior is lined with endothelial cells called tunica intima. The precise location of veins varies much more from person ... Microscopically, veins have a thick outer layer made of connective tissue, called the tunica externa or tunica adventitia. ... The middle layer of bands of smooth muscle are called tunica media and are, in general, much thinner than those of arteries, as ...
Artery
The innermost layer, which is in direct contact with the flow of blood, is the tunica intima, commonly called the intima. The ... It consists of three tunics: Tunica media, intima, and external. Systemic arteries are the arteries (including the peripheral ... The outermost layer of an artery (or vein) is known as the tunica externa, also known as tunica adventitia, and is composed of ... Inside this layer is the tunica media, or media, which is made up of smooth muscle cells, elastic tissue (also called ...
Fenestra
The elastic layer of the tunica intima is a fenestrated membrane. In surgery, a fenestration is a new opening made in a part of ...
Basement membrane
Tunica intima - Inner layer of blood vessel Pozzi A, Yurchenco PD, Iozzo RV (January 2017). "The nature and biology of basement ...
Blood vessel
A thin membrane of elastic fibers in the tunica intima run parallel to the vessel. The middle layer tunica media is the ... The middle layer is thicker in the arteries than it is in the veins: The inner layer, tunica intima, is the thinnest layer. It ... The tunica media is thicker in the arteries rather than the veins. The outer layer is the tunica adventitia and the thickest ... The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. ...
Arteriosclerosis obliterans
842 It is characterized by fibrosis of the tunica intima and calcification of the tunica media. Arteriosclerosis Monckeberg's ...
Tunica media
It lies between the tunica intima on the inside and the tunica externa on the outside. Tunica media is made up of smooth muscle ... It lies between the tunica intima on the inside and the tunica externa on the outside. The middle coat (tunica media) is ... The tunica media (New Latin "middle coat"), or media for short, is the middle tunica (layer) of an artery or vein. ... tunica intima) by its color and by the transverse arrangement of its fibers. In the smaller arteries it consists principally of ...
Superior vena cava
... starting with the innermost endothelial tunica intima. The middle layer is the tunica media, composed of smooth muscle tissue, ... The tunica adventitia contains three zones, with the middle zone consisting of few smooth muscle fibers; this differs from the ... and the outermost and thickest layer is the tunica adventitia, composed of collagen and elastic connective tissue that allow ...
Atheroma
... the tunica intima, media, and adventitia. Atheroma and changes in the artery wall usually result in small aneurysms ( ... is always in the tunica intima, between the endothelium lining and the smooth muscle middle layer of the artery wall.[citation ... Regression analysis revealed that thickening of the mean intima-media complex more than 1.0 was predictive of significant CAD ... Promising results are found using carotid intima-media thickness scanning (CIMT can be measured by B-mode ultrasonography), B- ...
Aortic aneurysm
Most AAA are true aneurysms that involve all three layers (tunica intima, tunica media and tunica adventitia). The prevalence ...
Eosinophilic myocarditis
The intima, tunica media, and tunica intima layers of these arteries remain intact and are generally unaffected. Thus, this ...
Foam cell
... s form the fatty streaks of the plaques of atheroma in the tunica intima of arteries. Foam cells are not dangerous as ... In chronic hyperlipidemia, lipoproteins aggregate within the intima of blood vessels and become oxidized by the action of ...
Aorta
The vascular wall is subdivided into three layers known as the tunica externa, tunica media, and tunica intima. The aorta is ... which feed the tunica externa and tunica media, the outer layers of the aorta. The aortic arch contains baroreceptors and ... Within the tunica media, smooth muscle and the extracellular matrix are quantitatively the largest components, these are ...
Abdominal aortic aneurysm
The most striking histopathological changes of the aneurysmatic aorta are seen in the tunica media and intima layers. These ... However, the degradation of the tunica media by means of a proteolytic process seems to be the basic pathophysiologic mechanism ... the tunica media must rely mostly on diffusion for nutrition, which makes it more susceptible to damage. Hemodynamics affect ...
Capillary
Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are ...
Tunica externa
... an inner tunica intima, a middle tunica media, and an outer tunica externa. The tunica externa is made from collagen and ... The tunica externa (New Latin "outer coat"), also known as the tunica adventitia (New Latin "additional coat"), is the ... The tunica externa provides basic structural support to blood vessels. It prevents vessels from expanding too much from ... Tunica adventitia is at 'a') Microphotography of arterial wall with calcified (violet colour) atherosclerotic plaque ( ...
Hyperplasia
Intimal hyperplasia - The thickening of the tunica intima of a blood vessel as a complication of a reconstruction procedure or ...
Intimal hyperplasia
... is the thickening of the tunica intima of a blood vessel as a complication of a reconstruction procedure or ...
Resistance artery
Like all other arteries, the vascular wall of resistance vessels can be split into three sections: the tunica intima, media, ... Endothelial cells in the tunica intima of these arteries are unique in that they can communicate directly with VSMCs through ... holes in the internal elastic lamina (IEL). Another distinct feature is the thick tunica media, which is mainly composed of ...
Vasa vasorum
... tunica media) layer almost to the inner (tunica intima) layer. In smaller vessels it penetrates only the outer layer. In the ... This means that it would take longer for any oxygen to diffuse through to the cells in the tunica adventitia and the tunica ... These small vessels serve to provide blood supply and nourishment for tunica adventitia and outer parts of tunica media of ... In the human descending aorta, vasa vasorum cease to supply the arterial tunica media with oxygenated blood at the level of the ...
Carotid artery dissection
... known as the tunica intima). Blood is then able to enter the space between the inner and outer layers of the vessel, causing ...
Lymph heart
There are the tunica interna intima made up of endothelial cells, tunica media made up of muscle, and the tunica externa for ...
Tunica (biology)
In arteries and veins the inner wall is the tunica intima, the outer wall is the tunica adventitia, and they are separated by ... Tunica serosa is the serous membrane Tunica vaginalis is the serous covering of the testis within the scrotum. Tunica vasculosa ... In human anatomy it generally refers either to Tunica vasculosa lentis or to Tunica vasculosa testis "tunica". Dictionary.com ... Tunica fibrosa oculi, is the fibrous tunic of the eyeball, the outer layer that includes both the cornea and sclera. Tunica ...
Glossary of ancient Roman culture
Stola Long, pleated dress, worn over an undergarment called a tunic or tunica intima, usually sleeveless but versions of it did ...
13-Hydroxyoctadecadienoic acid
... atheromatous plaques accumulate in the vascular tunica intima thereby narrowing blood vessel size and decreasing blood flow. In ...
Neointimal hyperplasia
... refers to proliferation and migration of vascular smooth muscle cells primarily in the tunica intima, ... is used because the cells in the hyperplastic regions of the vascular wall have histological characteristics of both intima and ...
Atherosclerosis
The ensuing inflammation leads to the formation of atheromatous plaques in the arterial tunica intima, a region of the vessel ... there is also smooth muscle proliferation and migration from the tunica media into the intima in response to cytokines secreted ... The fibrous plaque is also localized under the intima, within the wall of the artery resulting in thickening and expansion of ... Provost EB, Madhloum N, Int Panis L, De Boever P, Nawrot TS (2015). "Carotid intima-media thickness, a marker of subclinical ...
Aortic arch
The tunica intima, which surrounds the lumen and is composed of simple squamal epithelial cells; the tunica media, composed of ... smooth cell muscles and elastic fibers; and, the tunica adventitia, composed of loose collagen fibers. Innervated by barometric ...
Tunica
... surrounding the tunica media Tunica intima, for short, is the innermost tunica (layer) of an artery or vein Tunica, a flowering ... Mississippi Tunica County, Mississippi Tunica Lake, Lee County, Arkansas and Tunica County, Mississippi Tunica Academy, a non- ... Look up tunica in Wiktionary, the free dictionary. Tunica may refer to: The Latin word for tunic, a type of clothing typical in ... a Native American group in the central Mississippi River Valley Tunica language, an isolate of the associated Tunica historic ...
Cervical artery dissection
... s begin initially with a small tear in the innermost layer of the arterial wall, the tunica intima, ... Arterial walls are composed of three layers: an intima (the innermost layer), media (the middle muscular layer), and adventitia ...
Vertebral artery dissection
This is most likely due to a tear in the tunica intima (the inner layer), allowing blood to enter the tunica media, although ...
Endothelium
Platelet activation Susac's syndrome Tunica intima VE-cadherin Weibel-Palade body Angiocrine growth factors Endothelial Cell ... This state of endothelial cells promotes accumulation of lipids and lipoproteins in the intima, leading to atherosclerosis, and ... The lesions formed in the intima, and persistent inflammation lead to desquamation of endothelium, which disrupts the ...
Aneurysm
The third stage of syphilis also manifests as aneurysm of the aorta, which is due to loss of the vasa vasorum in the tunica ... A true aneurysm is one that involves all three layers of the wall of an artery (intima, media and adventitia). True aneurysms ...
Dissection (medical)
... a layer of the tunica intima or tunica media), a dissection creates two lumens or passages within the vessel, the native or ...
Pseudoaneurysm
... tunica intima) and subsequent dissection/separation between tunica intima and tunica media. Pseudoaneurysm being close to the ...
Generalized arterial calcification of infancy
... leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the ...
Glomerulocystic kidney disease
... meaning a layer of the blood vessel called tunica intima may thicken and the blood vessels will have a smaller opening ...
List of MeSH codes (A10)
... tunica intima MeSH A10.272.497 - epidermis MeSH A10.272.497.500 - hair follicle MeSH A10.272.510 - epithelium, corneal MeSH ... tunica media MeSH A10.690.467.500 - myometrium MeSH A10.690.637 - myocardium MeSH A10.755.260 - ependyma MeSH A10.755.503 - ...
Intima-media thickness
... (IMT), also called intimal medial thickness, is a measurement of the thickness of tunica intima and ... Although carotid intima-media thickness is strongly associated with atherosclerosis, thickening of the intima-media may not ... Various Newscasts on Carotid IMT (Intima Media Thickness) Bortel L (2005). "What does intima-media thickness tell us?". Journal ... Intima-medial thickening is a complex process, depending on a variety of factors, including blood pressure, local hemodynamics ...
Thoracic Duct Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Tunica intima. The luminal and valvular surfaces of the duct and cisterna chili are covered by endothelial cells, which measure ... The tunica media is the thickest coat of the thoracic duct and consists of 4-9 layers of smooth muscle cells organized into ... The tunica adventitia is the outermost layer of the thoracic duct. It consists of a connective tissue complex, which includes ... Near the tunica media, there is a layer of collagen fibrils disposed mainly longitudinally. This layer merges with the ...
Steroid receptor coactivator-3 is required for inhibition of neointima formation by estrogen
Thromboangiitis Obliterans (Buerger Disease): Practice Essentials, Pathophysiology and Etiology, Epidemiology
Aorta: Anatomy and Function
Inner layer (tunica intima): This is the tube through which blood passes. It contains smooth muscle tissue, connective tissue ... Outer layer (tunica adventitia): The outer layer anchors the aorta in place. It also connects to nearby nerves and tissue. ... Middle layer (tunica media): This layer is made of smooth muscle tissue, elastin and collagen (proteins). These substances ...
Histology of the CVS Flashcards by Mollie O | Brainscape
Internal elastic lamina between the tunica intima and media, and an external elastic lamina between tunica media and tunica ... If blood somehow breaks the endothelium and works its way into the tunica media, it can start getting between the elastic ... Why are the muscle cells of the tunica media connected by gap junctions in muscular arteries? ... Depolarisation is propagated to all cells of the tunica media via gap junctions ...
Publication Detail
Abdominal Aortic Aneurysm Causes, Treatment, Symptoms & Survival Rate
Thoracic Duct Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Tunica intima. The luminal and valvular surfaces of the duct and cisterna chili are covered by endothelial cells, which measure ... The tunica media is the thickest coat of the thoracic duct and consists of 4-9 layers of smooth muscle cells organized into ... The tunica adventitia is the outermost layer of the thoracic duct. It consists of a connective tissue complex, which includes ... Near the tunica media, there is a layer of collagen fibrils disposed mainly longitudinally. This layer merges with the ...
Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery...
Tunica Intima / pathology* Actions. * Search in PubMed * Search in MeSH * Add to Search ... Carotid intima-media thickness for the practicing lipidologist. Liviakis L, Pogue B, Paramsothy P, Bourne A, Gill EA. Liviakis ... Causes of changes in carotid intima-media thickness: a literature review. Qu B, Qu T. Qu B, et al. Cardiovasc Ultrasound. 2015 ... Carotid intima-media thickness as a marker of cardiovascular risk in hypertensive patients with coronary artery disease. ...
Trait antagonism and the progression of arterial thickening: women with antagonistic traits have similar carotid arterial...
Tunica Intima / pathology* Actions. * Search in PubMed * Search in MeSH * Add to Search ... Carotid intima-media thickness: knowledge and application to everyday practice. Cobble M, Bale B. Cobble M, et al. Postgrad Med ... Carotid intima-media thickness measurement in cardiovascular screening programmes. Plantinga Y, Dogan S, Grobbee DE, Bots ML. ... Predicted standardized intima-media thickness values as a function of Agreeableness and sex. The Agreeableness × sex ...
These highlights do not include all the information needed to use TURALIO safely and effectively. See full prescribing...
Free Science Flashcards about Pathology Cumulative
What are the similarities between arteries and veins?
both types of blood vessels have a layer called tunica intima in their walls. ... Walls of arteries and veins are made up of three layers namely tunica externa, tunica media, and tunica interna….Complete ... Tunica adventitia (tunica externa) is the outer layer of a blood vessel,… 2 Middle. The middle layer of the walls of arteries ... and veins is called the tunica media. 3 Inner. The inner layer of the blood vessel wall is called tunica intima. ...
Details - Public Health Image Library(PHIL)
TREE NUMBER DESCRIPTOR
cGMP mediated smooth muscle vasodilators | Osmosis
The innermost tunic is the tunica intima, which includes the endothelial cells; the next one is the tunica media, or middle ... Now, within endothelial cells of the tunica intima, theres an enzyme called nitric oxide synthase, which uses the amino acid L ... Moreover, the tunica media can contract, causing vasoconstriction, where the lumen gets a lot smaller; or it can relax, or ... Once synthesized, nitric oxide diffuses to adjacent smooth muscle cells in the tunica media, where it binds and activates an ...
Intimal-medial thickness and carotid arteries lumen in irradiated patients for head and neck cancer: Preliminary data of an...
Imaging in acute trauma-induced dissection and ischemic stroke: A Review
Flashcards - Cardiovascular Histology
1. Tunica intima (inner, endocardium)*2. Tunica media (middle, myocardium)*3. Tunica adventitia (outer, epicardium) ... Tunica Intima*- endothelial cells rest on thin subendothelium*- internal elastic lamina not usually visible*Tunica Media*- ... Tunica Intima *- very thin*- valves formed by subendothelial CT (not in large veins)*- valves have covering of endothelium. * ... Tunica Intima *Lumenal (inner) layer*Endothelium (simple squam.) contacts blood*Subendothelium (loose CT / some smooth m. cells ...
Arteries- Introduction, Types, Differences anf FAQs
C74167|Sulmepride|modify|27-JUN-08|(null)|(null
The Relationship of Active and Passive Smoking to Carotid Atherosclerosis 12-14 Years Later<...
Caspase-3 and Tissue Factor Expression in Lipid-Rich Plaque Macrophages: Evidence for Apoptosis as Link between Inflammation...
Resveratrol
Risk factors and segment-specific carotid arterial enlargement in the Atherosclerosis Risk in Communities (ARIC) cohort<...
Colony Stimulating Factor-1 in Graft Vascular Disease - Northwestern Scholars
DeCS
Intimas, Vascular. Intimas, Venous. Tunica Intima Vasorum. Vascular Intima. Vascular Intimas. Venous Intima. Venous Intimas. ... Intima, Vascular Intimas, Vascular Tunica Intima Vasorum Vascular Intima Vascular Intimas Arterial Intima - Narrower Concept UI ... Arterial Intima. Arterial Intimas. Intima, Arterial. Intima, Vascular. Intima, Venous. Intimas, Arterial. ... Tunica Intima - Preferred Concept UI. M0026599. Scope note. The innermost layer of an artery or vein, made up of one layer of ...
Artery6
- The tunica intima, or intima for short, is the innermost tunica (layer) of an artery or vein. (combster.tv)
- Carotid intima-media wall thickness (IMT) and carotid plaques were measured in the right common carotid artery. (nih.gov)
- Carotid artery dissection begins as a tear in the tunica intima or directly within the tunica media (possibly originating from the vasa vasorum). (medscape.com)
- A) Tear and elevation of intima from wall of artery, resulting in luminal stenosis. (medscape.com)
- Phenylbutazone was able to cause arterial damage, mainly in the tunica intima of the artery in which the medication was administered, with perivascular inflammatory infiltrate and subsequent skin necrosis at the site of administration. (ufrgs.br)
- The most common clinical detection of atherosclerosis is to measure the intima-media thickness (IMT) of common carotid artery by using ultrasonic imaging. (biomedcentral.com)
Adventitia2
- Sometimes, the dissection plane lies between the tunica media and the tunica adventitia, resulting in an aneurysmal outpouching of the arterial wall that may also become a source of distal emboli. (medscape.com)
- Tunica Adventitia, T. Media and T. Intima. (epainassist.com)
Outermost layer1
- Tunica externa (outermost layer). (3d4medical.com)
Aortic2
- The neoplasm arises from the tunica intima of the aorta and fills the aortic lumen. (avma.org)
- The aortic tunica intima in young and aging rats. (wikidata.org)
EXTERNA1
- C, Tunica externa. (co.ma)
Innermost layer2
- Note the fatty deposits, or plaque, that coated the artery's innermost layer, the tunica intima. (cdc.gov)
- Tunica intima (innermost layer). (3d4medical.com)
Veins3
- Arteries generally have a thicker tunica media than veins and mainly rely on this muscle for their transport of blood. (3d4medical.com)
- Veins have a thinner tunica media, and are less flexible than arteries. (3d4medical.com)
- In the majority of the veins the tunica intima includes an internal endothelial layer, a middle layer of subendothelial connective tissue, and an outer layer of elastic tissue. (co.ma)
Arteries2
- Similarly, the intima to media ratio (I:M) of the balloon injured carotid arteries in A1 fed animals (0.77+/-0.07) was higher than in those that consumed A2 (0.57+/-0.04) or whey (0.58+/-0.04), but this did not reach significance. (bris.ac.uk)
- Abnormalities found included muscularization of pulmonary arterioles, the development of longitudinal muscle in the intima of pulmonary arteries and arterioles, and the formation of muscular tubes lining the longitudinal muscle which extended through arterioles into the precapillaries of the lung. (umsa.bo)
Atherosclerosis2
- Atherosclerosis begins when the cholesterol transport protein enters the wall of the tunica media, whose first layer is the endothelium. (captivate.fm)
- This paper presents quantitative analysis of blood flow shear stress by measuring the carotid arterial wall shear stress (WSS) and the intima-media thickness (IMT) of experimental rabbits fed with high-fat feedstuff on a weekly basis in order to cause atherosclerosis. (biomedcentral.com)
Vein2
- The right vein is opened throughout in the anterior segment, revealing the orifice of a feeder vein and two venous valves, i.e. flap valves, formed by a duplication of the tunica intima. (boreal.com)
- Histopathological examination confirmed the vein which was showing destruction of tunica intima as in chronic inflammatory condition. (who.int)
MEDIA1
- Tunica media (middle layer). (3d4medical.com)
Lumen1
- Illustration shows stasis of flow in false lumen beneath elevated intima. (medscape.com)
Endothelial Cells1
- Mononuclear cell infiltration of the arterial intima occurs in the absence of C6, but C6 deficiency limits the release of vWF from arterial endothelial cells. (elsevier.com)
Folds1
- One of the chief peculiarities of the tunica intima is the presence of folds of its substance which constitute valves. (co.ma)
Monocytes1
- Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus. (monocyte.eu)
Endothelial cells6
- Now, within endothelial cells of the tunica intima, there's an enzyme called nitric oxide synthase, which uses the amino acid L-arginine and molecular oxygen to synthesize nitric oxide or NO for short. (osmosis.org)
- The inner surface of the intima, called the endothelium, is lined with endothelial cells. (healthvigil.com)
- Proliferation of endothelial cells and fibrosis in the tunica intima narrows and ultimately occludes the blood vessel. (pathwaymedicine.org)
- Arteries, veins, and capillaries have a tunica intima comprised of endothelial cells (EC), which regulate coagulation, confer selective permeability, and participate in immune cell trafficking ( Herbert and Stainier, 2011 , Potente et al. (issca.us)
- a middle layer of smooth muscle called the tunica media , and the inner layer lined with endothelial cells called the tunica intima . (enwik.org)
- The interior is lined with endothelial cells called tunica intima . (enwik.org)
Externa2
- and finally, there's the tunica externa, or outside tunic, which is made up of loosely woven fibers of collagen. (osmosis.org)
- and the outer layer (tunica externa) has connective tissue. (thefreedictionary.com)
Endothelium5
- Intimal proliferation (Figure 1, Figure 2, Figure 3, Figure 4, Figure 5, and Figure 6) is characterized by thickening of the tunica intima of blood vessels, with the normal single-layered intima, beneath the endothelium, expanded into a multilayered cellular lining. (nih.gov)
- The tunica intima of the cardiovascular system is composed of a layer of endothelium which is invested with a basement membrane lying on top of a thin collagenous meshwork. (pathwaymedicine.org)
- The inner portion of the tunica intima is called the endothelium. (clinicalanatomy.com)
- 10 The tunica intima includes the endothelium , a single layer of cells that makes direct contact with the blood. (nordic.com)
- The tunica intima, the innermost layer, is composed of an inner surface of smooth endothelium that is covered by an outer surface of elastic tissues, which is the most superficial layer. (diverseyyachtclub.org)
Thickness16
- Carotid artery intima-media thickness (CIMT) is a subclinical marker of atherosclerosis associated with stroke. (nih.gov)
- Using a large, community-based sample from Sardinia, Italy (n=5614), this study examined how trait antagonism (low agreeableness) and its facets are associated with carotid artery intima-media thickness, a measure of arterial thickening. (nih.gov)
- Controlling for demographic and cardiovascular risk factors, low agreeableness and, in particular, low straightforwardness and low compliance, were associated with greater carotid thickening, measured concurrently and prospectively, and with increases in intima-media thickness over 3 years. (nih.gov)
- Indeed, those in the bottom 10% of agreeableness had a 40% increase in risk for elevated intima-media thickness. (nih.gov)
- The increased thickness of the intima results from a combination of endothelial hypertrophy, proliferation of smooth muscle cells, and accumulation of glycosaminoglycans. (nih.gov)
- Variations in carotid artery intima-media thickness during the cardiac" by Spencer Menees, Danna Zhang et al. (childrensmercy.org)
- Variations in carotid artery intima-media thickness during the cardiac cycle in children. (childrensmercy.org)
- BACKGROUND: There is paucity of research looking at variations in carotid artery intima-media thickness (CIMT) during the cardiac cycle in children. (childrensmercy.org)
- Markers of coronary atherosclerosis, including brachial artery flow-mediated dilation, carotid intima-media thickness, and high-sensitivity C-reactive protein, were measured before GBS and 6, 12, and 24 months after GBS. (omeka.net)
- Long-term health benefits and costs of measurement of carotid intima-media thickness in prevention of coronary heart disease. (nih.gov)
- den Ruijter HM, Vaartjes I, Sutton-Tyrrell K, Bots ML, Koffijberg H. Long-term health benefits and costs of measurement of carotid intima-media thickness in prevention of coronary heart disease. (nih.gov)
- OBJECTIVE: Recently, it was demonstrated that information on carotid intima-media thickness (CIMT) and plaque may improve coronary heart disease (CHD) risk prediction through reclassification of some individuals to the correct risk category using the Framingham risk score. (nih.gov)
- Furthermore, we studied the mean intima-media thickness of the common carotid artery in relation to hypertension, smoking, and the HFE genotype in subjects without stroke. (ox.ac.uk)
- Clinical ultrasound is typically implemented for measuring intima-media thickness, which allows medical experts to be able to determine if they should intervene clinically [ 31 ]. (biomedcentral.com)
- The primary endpoint was progression of mean distal carotid intima-media thickness (cIMT) over 18 months in the modified intention-to-treat population. (ox.ac.uk)
- Increased thickness of intima-media layers in the distal right common carotid artery. (jamanetwork.com)
Atherosclerosis3
- Atherosclerosis begins to develop when the inner layer of the arterial wall, the tunica intima, gets damaged. (healthvigil.com)
- The initiating injury in atherosclerosis appears to be deposition of LDL lipid particles and their subsequent oxidation in the tunica intima. (pathwaymedicine.org)
- Atherosclerosis is a buildup of lipids and fibrous material just under the inner lining of the blood vessel, called the tunica intima . (osmosis.org)
Aortic1
- use AORTIC ANEURYSM, THORACIC 2008-2022 BX - TAA Thoracoabdominal Aortic Aneurysm MH - Aortic Intramural Hematoma UI - D000094666 MN - C14.907.109.70.625 MN - C23.550.414.838.175 MS - An atypical form of AORTIC DISSECTION in which subintimal dissection of the aortic TUNICA MEDIA without initial laceration of the aortic TUNICA INTIMA. (nih.gov)
Media17
- There is a distinct demarcation between the thickened tunica intima and the tunica media (arrows). (nih.gov)
- The junction between tunica media and the tunica intima (arrows) is distinct. (nih.gov)
- The line of demarcation between the proliferating tunica intima and the tunica media (arrows) is conspicuous. (nih.gov)
- These cells express growth factors that promote smooth muscle cel migration from the tunica media into the intima. (nih.gov)
- Once synthesized, nitric oxide diffuses to adjacent smooth muscle cells in the tunica media, where it binds and activates an enzyme guanylyl cyclase. (osmosis.org)
- A carotid or vertebral artery dissection starts of as a tear in the tunica intima or directly within the tunica media. (appliedradiology.com)
- What synthesizes all the ECM in the tunica media? (freezingblue.com)
- What separates the t. intima and t. media? (freezingblue.com)
- For example, the myocardium of the heart is a giant expansion of the tunica media, while capillaries do not possess this particular layer at all. (pathwaymedicine.org)
- The middle layer is called the "tunica media" and is composed by a varying number of elastic fibers and smooth muscle fibers arranged as shown in the image. (clinicalanatomy.com)
- The tunica media, or middle layer, is made of smooth muscle and elastic connective tissue. (ipsnews.info)
- The tunica media is the middle layer, and is composed of alternating layers of muscle and structural fibers. (nordic.com)
- Nitric oxide then travels into the middle (tunica media) of the blood vessel and causes the muscle layer to relax. (nordic.com)
- As the atherosclerotic plaque grows, vascular smooth muscle cells migrate into the lesion, likely from the tunica media, proliferate, and begin elaborating extracellular matrix. (pathwaymedicine.org)
- The tunica media also contains various amounts of elastic and collagen fibers. (byui.edu)
- The tunica media is composed of smooth muscle tissue, but contains few layers. (byui.edu)
- The tunica media has less smooth muscle in it. (byui.edu)
Vascular3
- These cells proliferate in the tunica intima and deposit extracellular matrix, leading to thickening of the intima and a reduction in the vascular lumen. (nih.gov)
- Atherosclerotic plaques appear to begin as "Fatty Streaks" which represent focal accumulations of lipids in the vascular tunica intima. (pathwaymedicine.org)
- Why LDL particles begin to deposit in the vascular intima is still begin understood, although increased levels of plasma LDL observed as hyperlipidemia clearly contribute. (pathwaymedicine.org)
Artery3
- This 3D medical animation shows an artery wall "blocked", or occluded, by a thrombus (stationary) plaque formation.rnrnAs blood cells and other elements flow through the arterial lumen, the interior wall of the blood vessel (tunica intima) tears, allowing cholesterol deposits to form a plaque thrombus within the wall itself. (smartimagebase.com)
- The excision of the thickened, atheromatous tunica intima of a carotid artery. (uchicago.edu)
- It is intima that stands between the blood and your artery wall. (healthvigil.com)
Connective1
- The innermost tunica intima is composed of an endothelial layer, a connective tissue basement membrane and a slim layer of connective tissue known as the lamina propria. (byui.edu)
Blood2
- The inner layer of the blood vessel wall is called tunica intima. (onteenstoday.com)
- The tunica intima of a deep vein usually has a one-way valve to prevent blood from flowing backward. (proudme.online)
Interna1
- What is tunica interna? (diverseyyachtclub.org)
Internal1
- The tunica intima does not have an internal elastic membrane. (byui.edu)