Common Bile Duct: The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.Common Bile Duct Neoplasms: Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Common Bile Duct Diseases: Diseases of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Bile Ducts: The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.Cholangiopancreatography, Endoscopic Retrograde: Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.Cholangiography: An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.Bile: An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.Bile Duct Diseases: Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT.Choledocholithiasis: Presence or formation of GALLSTONES in the COMMON BILE DUCT.Bile Ducts, Extrahepatic: Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).Cholestasis, Extrahepatic: Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.Cholecystectomy, Laparoscopic: Excision of the gallbladder through an abdominal incision using a laparoscope.Cholecystectomy: Surgical removal of the GALLBLADDER.Sphincterotomy, Endoscopic: Incision of Oddi's sphincter or Vater's ampulla performed by inserting a sphincterotome through an endoscope (DUODENOSCOPE) often following retrograde cholangiography (CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE). Endoscopic treatment by sphincterotomy is the preferred method of treatment for patients with retained or recurrent bile duct stones post-cholecystectomy, and for poor-surgical-risk patients that have the gallbladder still present.Bile Acids and Salts: Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Jaundice, Obstructive: Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.Cholangiopancreatography, Magnetic Resonance: Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.Sphincter of Oddi: The sphincter of the hepatopancreatic ampulla within the duodenal papilla. The COMMON BILE DUCT and main pancreatic duct pass through this sphincter.Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.Cystic Duct: The duct that is connected to the GALLBLADDER and allows the emptying of bile into the COMMON BILE DUCT.Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).Ampulla of Vater: A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.Pancreatic Ducts: Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.Biliary Tract Diseases: Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Biliary Tract: The BILE DUCTS and the GALLBLADDER.Ligation: Application of a ligature to tie a vessel or strangulate a part.Gallbladder: A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.Sphincterotomy, Transhepatic: Surgery of the smooth muscle sphincter of the hepatopancreatic ampulla to relieve blocked biliary or pancreatic ducts.Biliary Tract Surgical Procedures: Any surgical procedure performed on the biliary tract.Choledochal Cyst: A congenital anatomic malformation of a bile duct, including cystic dilatation of the extrahepatic bile duct or the large intrahepatic bile duct. Classification is based on the site and type of dilatation. Type I is most common.Biliary Fistula: Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.Choledochostomy: Surgical formation of an opening (stoma) into the COMMON BILE DUCT for drainage or for direct communication with a site in the small intestine, primarily the DUODENUM or JEJUNUM.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Endoscopes: Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.Duodenoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the duodenum.Cholecystitis: Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.Imino AcidsGallbladder Diseases: Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.Lithotripsy: The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.Adenomyoma: A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)Gallbladder Neoplasms: Tumors or cancer of the gallbladder.Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Technetium Tc 99m Disofenin: A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)Endoscopy, Digestive System: Endoscopic examination, therapy or surgery of the digestive tract.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Pancreaticoduodenectomy: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).Cholecystitis, Acute: Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.Sphincter of Oddi Dysfunction: Organic or functional motility disorder involving the SPHINCTER OF ODDI and associated with biliary COLIC. Pathological changes are most often seen in the COMMON BILE DUCT sphincter, and less commonly the PANCREATIC DUCT sphincter.Jejunostomy: Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.Cholecystolithiasis: Presence or formation of GALLSTONES in the GALLBLADDER.Duodenum: The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.Bilirubin: A bile pigment that is a degradation product of HEME.Pancreatic Diseases: Pathological processes of the PANCREAS.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)Duodenal Neoplasms: Tumors or cancer of the DUODENUM.Intraoperative Period: The period during a surgical operation.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Endosonography: Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously.Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.Cholecystostomy: Establishment of an opening into the gallbladder either for drainage or surgical communication with another part of the digestive tract, usually the duodenum or jejunum.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Bile Reflux: Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Liver Cirrhosis, Experimental: Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.Lithotripsy, Laser: Fragmentation of CALCULI, notably urinary or biliary, by LASER.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Liver Function Tests: Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Thoracic Duct: The largest lymphatic vessel that passes through the chest and drains into the SUBCLAVIAN VEIN.Calculi: An abnormal concretion occurring mostly in the urinary and biliary tracts, usually composed of mineral salts. Also called stones.Adenocarcinoma, Papillary: An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Ascaridida: An order of nematodes of the subclass SECERNENTEA. Its organisms possess two or three pairs of dorsolateral caudal papillae.Pancreas: A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.Lithiasis: A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Hepatopulmonary Syndrome: A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Colic: A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Liver Neoplasms: Tumors or cancer of the LIVER.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Pancreatitis, Chronic: INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)Ursodeoxycholic Acid: An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.Diverticulum: A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.Anastomosis, Roux-en-Y: A Y-shaped surgical anastomosis of any part of the digestive system which includes the small intestine as the eventual drainage site.Tumor Burden: The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Liver Diseases: Pathological processes of the LIVER.Cell Line, Tumor: A cell line derived from cultured tumor cells.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Cholecystography: Radiography of the gallbladder after ingestion of a contrast medium.Bile Canaliculi: Minute intercellular channels that occur between liver cells and carry bile towards interlobar bile ducts. Also called bile capillaries.Cholagogues and Choleretics: Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic).Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Postcholecystectomy Syndrome: Abdominal symptoms after removal of the GALLBLADDER. The common postoperative symptoms are often the same as those present before the operation, such as COLIC, bloating, NAUSEA, and VOMITING. There is pain on palpation of the right upper quadrant and sometimes JAUNDICE. The term is often used, inaccurately, to describe such postoperative symptoms not due to gallbladder removal.Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.Salivary Ducts: Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Mixed Tumor, Malignant: A malignant tumor composed of more than one type of neoplastic tissue. (Dorland, 27th ed)Iatrogenic Disease: Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.Technetium Tc 99m Lidofenin: A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.Cysts: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Bile Pigments: Linear TETRAPYRROLES that give a characteristic color to BILE including: BILIRUBIN; BILIVERDIN; and bilicyanin.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Digestive System Neoplasms: Tumors or cancer of the DIGESTIVE SYSTEM.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Skin Neoplasms: Tumors or cancer of the SKIN.Dilatation: The act of dilating.Video-Assisted Surgery: Endoscopic surgical procedures performed with visualization via video transmission. When real-time video is combined interactively with prior CT scans or MRI images, this is called image-guided surgery (see SURGERY, COMPUTER-ASSISTED).Duodenal Obstruction: Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Hemobilia: Hemorrhage in or through the BILIARY TRACT due to trauma, inflammation, CHOLELITHIASIS, vascular disease, or neoplasms.Wolffian Ducts: A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.Genes, Tumor Suppressor: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.Kidney Neoplasms: Tumors or cancers of the KIDNEY.Amylases: A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.Taurocholic Acid: The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.Pancreatic Pseudocyst: Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.Foreign-Body Migration: Migration of a foreign body from its original location to some other location in the body.Acute Disease: Disease having a short and relatively severe course.Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.Manometry: Measurement of the pressure or tension of liquids or gases with a manometer.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Digestive System Fistula: An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Mullerian Ducts: A pair of ducts near the WOLFFIAN DUCTS in a developing embryo. In the male embryo, they degenerate with the appearance of testicular ANTI-MULLERIAN HORMONE. In the absence of anti-mullerian hormone, mullerian ducts give rise to the female reproductive tract, including the OVIDUCTS; UTERUS; CERVIX; and VAGINA.Pancreatic Fistula: Abnormal passage communicating with the PANCREAS.Methods: A series of steps taken in order to conduct research.Neoplasms, Cystic, Mucinous, and Serous: Neoplasms containing cyst-like formations or producing mucin or serum.Bacterial Translocation: The passage of viable bacteria from the GASTROINTESTINAL TRACT to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the INTESTINAL MUCOSA resulting in increased intestinal permeability. Bacterial translocation from the lung to the circulation is also possible and sometimes accompanies MECHANICAL VENTILATION.DNA, Neoplasm: DNA present in neoplastic tissue.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Biliary Atresia: Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.Recurrence: The return of a sign, symptom, or disease after a remission.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.Pressure: A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Biliary Tract Neoplasms: Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.
... common bile duct neoplasms MeSH C06.130.320.120 --- bile duct neoplasms MeSH C06.130.320.120.280 --- common bile duct neoplasms ... gallbladder neoplasms MeSH C06.301.371.205 --- esophageal neoplasms MeSH C06.301.371.308 --- gastrointestinal stromal tumors ... File "2006 MeSH Trees".) MeSH C06.130.120.120 --- bile duct neoplasms MeSH C06.130.120.120.280 --- common bile duct neoplasms ... bile duct neoplasms MeSH C06.301.120.250.250 --- common bile duct neoplasms MeSH C06.301.120.401 --- ...
... biliary tract neoplasms MeSH C04.588.274.120.250 --- bile duct neoplasms MeSH C04.588.274.120.250.250 --- common bile duct ... testicular neoplasms MeSH C04.588.322.762.500 --- sertoli-leydig cell tumor MeSH C04.588.322.894 --- thyroid neoplasms MeSH ... ureteral neoplasms MeSH C04.588.945.947.945 --- urethral neoplasms MeSH C04.588.945.956 --- venereal tumors, veterinary MeSH ... mixed tumor, malignant MeSH C04.557.435.530 --- mixed tumor, mesodermal MeSH C04.557.435.540 --- mixed tumor, mullerian MeSH ...
In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and ... a yellowing of the skin and eyes caused by obstruction of the bile duct), or weight loss. These signs and symptoms are not ... Serous cystic neoplasms can come to clinical attention in a variety of ways. The most common symptoms are very non-specific and ... mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because ...
... (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN ... The most common symptoms include abdominal pain, nausea and vomiting. The most common signs patients have when they come to ... a yellowing of the skin and eyes caused by obstruction of the bile duct), weight loss, and acute pancreatitis. These signs and ... Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. As such IPMN is ...
... which inhibit p62 complexes have links to primary biliary cirrhosis which destroys the bile ducts of the liver. Decreases in ... The most common of these complexes is the p62 complex, which is an assembly composed of NUP62, NUP58, NUP54 and NUP45. Another ... is commonly found in precancerous dysplasias and malignant neoplasms. Each individual nucleoporin is named according to its ... of the genes that encode for different nucleoporins also have been shown to be related to the formation of cancerous tumors. ...
Dixon, J. A.; Morgan, K. A.; Adams, D. B. (2009). "Management of common bile duct injury during partial gastrectomy". The ... Morgan, K. A.; Adams, D. B. (2010). "Solid Tumors of the Body and Tail of the Pancreas". Surgical Clinics of North America. 90 ... Ellis, C. T.; Barbour, J. R.; Shary, T. M.; Adams, D. B. (2010). "Pancreatic cyst: Pseudocyst or neoplasm? Pitfalls in ... Theruvath, T. P.; Morgan, K. A.; Adams, D. B. (2010). "Mucinous cystic neoplasms of the pancreas: How much preoperative ...
Most gastrinomas are found in the gastrinoma triangle; this is bound by the junction of cystic and common bile ducts, junction ... USC Emedicine The Johns Hopkins University Pancreatic Islet Cell Tumor / Pancreatic Endocrine Neoplasms webpage Surgery ... A gastrinoma is a tumor in the pancreas or duodenum that secretes excess of gastrin leading to ulceration in the duodenum, ...
Less common types include mucinous cystic neoplasm and intraductal papillary biliary neoplasm. The diagnosis may be supported ... Liver cancer can also form from other structures within the liver such as the bile duct, blood vessels and immune cells. Cancer ... whether due to spread of the initial tumor or formation of new tumors . Liver transplantation can also be considered in cases ... The majority of cholangiocarcimas occur in the hilar region of the liver, and often present as bile duct obstruction. If the ...
Patient information on extrahepatic bile duct tumors, from the National Cancer Institute. Cancer.Net: Bile Duct Cancer The ... Distal cholangiocarcinomas (those arising from the common bile duct) are generally treated surgically with a Whipple procedure ... Cholangiocarcinoma is a relatively rare neoplasm that is classified as an adenocarcinoma (a cancer that forms glands or ... Tumors occurring in the bile ducts within the liver are referred to as intrahepatic, those occurring in the ducts outside the ...
For example, a benign tumor of smooth muscle cells is called a leiomyoma (the common name of this frequently occurring benign ... gastrointestinal Colon cancer Extrahepatic bile duct cancer Gallbladder cancer Gastric (stomach) cancer Gastrointestinal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ... Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other ...
MRI is a great method to visualize the pancreatic ducts, PET scanning can reveal the metabolic activity of a tumor, EUS ... an abnormal yellowing of the skin and eyes often caused by blockage of the bile ducts) are more likely to have a pancreatic ... The most common include CT scan (computerized axial tomography), magnetic resonance imaging (MRI), positron emission tomography ... Some cysts are cancerous, and others, such as the intraductal papillary mucinous neoplasm (IPMN) are potentially precancerous. ...
... common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. The ... Tumor cells are crowded in a distinct layer beneath the vaginal epithelium ( cambium layer). Spindle-shaped tumor cells that ... Neoplasms of the Vulva and Vagina. in Holland-Frei Cancer Medicine - 6th Ed. Kufe, DW et al. editors. BC Decker Inc., Hamilton ... For botryoid rhabdomyosarcoma of the vagina, the most common clinical finding is vaginal bleeding but vaginal bleeding is not ...
This results when a cancer in the head of the pancreas obstructs the common bile duct as it runs through the pancreas. ... Solid pseudopapillary tumor is a rare low-grade neoplasm that mainly affects younger women, and generally has a very good ... Regardless of a tumor's location, the most common symptom is unexplained weight loss, which may be considerable. A large ... Pancreatic mucinous cystic neoplasms are a broad group of pancreas tumors that have varying malignant potential. They are being ...
The term 'neoplasm' is a synonym of "tumor". 'Neoplasia' denotes the process of the formation of neoplasms/tumors, the process ... are common precursors to development of the disordered and improperly proliferating clone of tissue in a malignant neoplasm. ... Bile acids, at high levels in the colons of humans eating a high fat diet, also cause DNA damage and contribute to colon cancer ... Discrete localized enlargements of normal structures (ureters, blood vessels, intrahepatic or extrahepatic biliary ducts, ...
This was seen in both cell culture and samples from tumors in patients that had been treated with methotrexate. A common ... bile duct cancer, pancreatic cancer, small intestine cancer and colon cancer. In the colon, a field defect probably arises by ... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... Cells in pre-malignant and malignant neoplasms (tumors) evolve by natural selection. This accounts for how cancer develops from ...
Other primary sites that have been reported include colon, rectum, stomach, gallbladder, bile ducts, small intestine, urinary ... The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they ... For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed ... Since the mucus tends to pool at the bottom of the abdominal cavity, it is common to remove the ovaries, fallopian tubes, ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ... Chapter 92 (benign liver tumors). ISBN 978-0071466332. .. *^ Hussain S, van den Bos I, Dwarkasing R, Kuiper J, den Hollander J ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ... Microscopic appearance is signet ring cell carcinoma, which is tumor cells with mucin droplet that displaces the nucleus to one ...
... common bile duct - comorbidity - compassionate use trial - complementary and alternative medicine - complete blood count (CBC ... tumor load - tumor marker - tumor model - tumor necrosis factor - tumor suppressor gene - tumor-derived - tumor-specific ... neoplasm - nephrotomogram - nephrotoxic - nephroureterectomy - nerve block - nerve grafting - nerve-sparing radical ... tumor - tumor antigen vaccine - tumor board review - tumor burden - tumor debulking - tumor infiltrating lymphocyte - ...
Neoplasms (cancers) Adenocarcinoma Carcinoid Gastrointestinal stromal tumor (GIST) Lymphoma Sarcoma Leiomyoma Metastatic tumors ... It also receives bile and pancreatic juice through the pancreatic duct, controlled by the sphincter of Oddi. The primary ... A few of them are listed below, some of which are common, with up to 10% of people being affected at some time in their lives, ... Pancreatic lipase works with the help of the salts from the bile secreted by the liver and stored in the gall bladder. Bile ...
The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck. ... A persistent thyroglossal duct is the most common clinically significant congenital disorder of the thyroid gland. A persistent ... Disorders of the thyroid are functional-caused by dysfunction in the production of hormones, and nodes and tumors either benign ... perhaps by increasing the rate of secretion of cholesterol in bile. Cardiovascular. The hormones increase the rate and strength ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... This article about a neoplasm is a stub. You can help Wikipedia by expanding it.. *v ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Digestive_system_neoplasm&oldid=898746878" ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Prognosis and treatment is the same as for the most common type of ovarian cancer, which is epithelial ovarian cancer.[5][6] ... cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ... Primary peritoneal carcinoma shows similar rates of tumor suppressor gene dysfunction (p53, BRCA, WT1) as ovarian cancer and ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ...
Bile ducts: 2. Intrahepatic bile ducts, 3. Left and right hepatic ducts, 4. Common hepatic duct, 5. Cystic duct, 6. Common bile ... A solid pseudopapillary tumour is a low-grade malignant tumour of the pancreas of papillary architecture that typically ... "Solid pseudopapillary neoplasm of the pancreas: a single institution experience of 14 cases". HPB. 8 (2): 148-50. doi:10.1080/ ... The intercalated ducts drain into larger ducts within the lobule, and finally interlobular ducts. The ducts are lined by a ...
... tumors are the most common malignant tumor of the appendix, but they are most commonly associated with the small ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ... The most common originating sites of carcinoid is the small bowel, particularly the ileum; carcinoid tumors are the most common ...
... bile duct tumors explanation free. What is bile duct tumors? Meaning of bile duct tumors medical term. What does bile duct ... Looking for online definition of bile duct tumors in the Medical Dictionary? ... Related to bile duct tumors: Common bile duct neoplasms. bile duct. [MIM*603003] 1. Synonym(s): common bile duct ... The duct continues down, as the common bile duct to run into the DUODENUM.. bile duct. the duct through which bile passes ...
... this tumor causes cystic dilation of the affected bile ducts as well as branched-type intraductal mucinous papillary neoplasm ... bile duct (● Fig.3). The filling defect in the intrahepatic bile duct was considered to be mucin. Therefore, we diagnosed this ... examination showed a malignant papillary proliferation within the dilated B4 bile duct and invasion into the bile duct wall on ... Because IPNB is really located within the intrahepatic bile duct, the main site of this tumor is within the liver. Although ...
... with secondary dilatation of the common bile duct (c) and main pancreat ... Common Bile Duct Neoplasms/mortality/pathology*/surgery*. *Lymph Nodes/pathology*. *Neuroendocrine Tumors/mortality/pathology*/ ... not invading the muscularis propria and with secondary dilatation of the common bile duct (c) and Wirsungs duct (W); d ... not invading the muscularis propria and with secondary dilatation of the common bile duct (c) and Wirsungs duct (W); d ...
... common bile duct neoplasms MeSH C06.130.320.120 --- bile duct neoplasms MeSH C06.130.320.120.280 --- common bile duct neoplasms ... gallbladder neoplasms MeSH C06.301.371.205 --- esophageal neoplasms MeSH C06.301.371.308 --- gastrointestinal stromal tumors ... File "2006 MeSH Trees".) MeSH C06.130.120.120 --- bile duct neoplasms MeSH C06.130.120.120.280 --- common bile duct neoplasms ... bile duct neoplasms MeSH C06.301.120.250.250 --- common bile duct neoplasms MeSH C06.301.120.401 --- ...
... biliary tract neoplasms MeSH C04.588.274.120.250 --- bile duct neoplasms MeSH C04.588.274.120.250.250 --- common bile duct ... testicular neoplasms MeSH C04.588.322.762.500 --- sertoli-leydig cell tumor MeSH C04.588.322.894 --- thyroid neoplasms MeSH ... ureteral neoplasms MeSH C04.588.945.947.945 --- urethral neoplasms MeSH C04.588.945.956 --- venereal tumors, veterinary MeSH ... mixed tumor, malignant MeSH C04.557.435.530 --- mixed tumor, mesodermal MeSH C04.557.435.540 --- mixed tumor, mullerian MeSH ...
MeSH-major] Bile Duct Neoplasms / radiotherapy. Brachytherapy. Hepatic Duct, Common. Klatskin Tumor / radiotherapy ... Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / drug therapy. Common Bile Duct Neoplasms / mortality. ... Bile Duct Neoplasms / pathology. Bile Ducts, Extrahepatic / pathology. Bile Ducts, Intrahepatic / pathology. Common Bile Duct ... MeSH-major] Bile Duct Neoplasms / diagnosis. Bile Duct Neoplasms / therapy. Bile Ducts, Extrahepatic. Bile Ducts, Intrahepatic ...
Neoplasm of common bile duct (disorder). English. MEDCIN 90387 L7089006. no. S8440197. Y. neoplasm of common bile duct ( ... Common Bile Duct Neoplasms. English. Medical Subject Headings D003138 L0009442. preferred. S0026745. Y. Common Bile Duct ... neoplasm of common bile duct. English. (MTHMST) Minimal Standard Terminology MT240015 L1834271. no. S2143100. Y. Main bile duct ... Common Bile Duct Neoplasms [Disease/Finding]. Finnish. Medical Subject Headings Finnish D003138 L5688483. preferred. S6521520. ...
Hepatic Duct, Common. Humans. Klatskin Tumor / diagnosis. Klatskin Tumor / therapy. Magnetic Resonance Imaging. Neoplasm ... Bile Duct Neoplasms / diagnosis. Bile Duct Neoplasms / pathology. Bile Duct Neoplasms / surgery. Bile Ducts, Intrahepatic / ... Bile Duct Neoplasms / genetics. Bile Duct Neoplasms / metabolism. Bile Duct Neoplasms / pathology. Bile Ducts, Intrahepatic / ... Bile Duct Neoplasms / pathology. Bile Duct Neoplasms / ultrasonography. Bile Duct Neoplasms / veterinary. Bile Ducts, ...
... malignant cystic neoplasms, endocrine neoplasms, squamous cell carcinoma, Vater and periampullary duodenal or common bile duct ... Willing to submit an evaluable tumor tissue sample, preferably from a liver metastasis, unless tumor is considered inaccessible ... Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Digestive System Neoplasms. Neoplasms by Site. ... Tumor lesions situated in a previously irradiated area are considered measurable if progression has been demonstrated in such ...
Common bile duct, Uncinate process Pancreatic pathology, Acute pancreatitis: diffuse , Acute pancreatitis: focal, Acute ... Cystic pancreatic neoplasms, Islet cell tumors, Lymphoma Sonography of the spleen, Normal spleen, Wandering spleen, ... common bile duct, crus of the diaphragm, cystic pancreatic neoplasm, cystic splenic mass, cystic splenic metastases, ... Pancreatic duct, Common bile duct, Uncinate process Pancreatic pathology, Acute pancreatitis: diffuse , Acute pancreatitis: ...
... hydatid cyst and intraductal papillary neoplasm of the bile duct. Affecting middle-aged female population, BMCN presents ... It can cause diagnostic dilemmas with most common differentials being complex hepatic cyst, ... and intraoperative cyst spillage should be avoided to prevent tumour dissemination. We present here a case with a very atypical ... Biliary mucinous cystic neoplasm (BMCN) is a rare intrahepatic neoplasm comprising approximately 5% of cystic liver lesions. ...
Benign tumors of the extrahepatic bile ducts. Report of three cases and review of the literature DOWDY GS Jr ... Benign neoplasms of the extrahepatic biliary ducts BURHANS R Am Surg 37, 161-166, 1971 ... Adenomyoma of the common bile duct imaged with endoscopic ultrasonography : case report ASCH MR ... Adenomyomatous Hyperplasia of the Common Bile Duct : Report of a Case * * IWAKI KENTARO ...
... is a malignant epithelial neoplasm composed of cells resembling cholangiocytes that line the intrahepatic bile ducts in portal ... Although ICC has been defined as a tumor arising from cholangiocyte transformation, recent evidence from genetic lineage- ... Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma.. [Maiko ...
Humans , Common Bile Duct Neoplasms/surgery , Ampulla of Vater , Choledochostomy , Endoscopy, Digestive System ... a practical approach to management of impacted papillary gallstones and ampullary tumors ... Common Bile Duct Neoplasms Limits: Humans Language: English Journal: Ann. Saudi Med. Year: 1992 ... Common Bile Duct Neoplasms Limits: Humans Language: English Journal: Ann. Saudi Med. Year: 1992 ...
Adenomyoma/pathology , Ampulla of Vater/pathology , Common Bile Duct Neoplasms/pathology , Female , Humans , Male ... Common Bile Duct Neoplasms Language: Korean Journal: The Korean Journal of Gastroenterology Year: 2013 Type: Article ... Necessity of Histologic Confirmation for Adequate Management in Ampullary Tumors Necessity of Histologic Confirmation for ...
TumorCommon Bile Duct NeoplasmsDuodenal NeoplasmsFemaleHumansImmunohistochemistryMaleMiddle AgedMucinsPancreatic Neoplasms ... Intrapancreatic distal common bile duct carcinoma: Analysis, staging considerations, and comparison with pancreatic ductal and ... Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ... An adenoma component common in ampullary-duodenal cancers was noted in only about a third. Most had plaque-like or ulcerating ...
In addition, tumors were analyzed for common oncogenic pathways, and the findings were correlated with subtype and grade. Data ... Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.. ... Intraductal papillary neoplasms of the bile duct from 45 patients were graded and subtyped using mucin markers and CDX2. ... Intraductal papillary neoplasms of the bile duct are still poorly characterized regarding (1) their molecular alterations ...
... is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and is regarded as a biliary ... The most common radiologic findings for IPNB are bile duct dilatation and intraductal masses. The major treatment of IPNB is ... Cholangioscopy can confirm the histology and assess the extent of the tumor including superficial spreading along the biliary ... Ultrasonography, computed tomography, magnetic resonance image, and cholangiography are usually performed to assess tumor ...
... or extrahepatic biliary ducts. It is the second-most common liver cancer, after hepatocellular carcinoma (HCC). About 6,000 ... Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Vaccines. Immunologic Factors. Physiological ... Changes in CA19.9 tumor marker induced by daily dose of oral vaccine V3-X of cholangiocarcinoma [ Time Frame: 2 months ]. open ... people in the United States develop bile duct cancer each year. One-year survival is less than 25% and no effective and safe ...
... the miRNA expression profiles of 63 human ICCs and nine normal intrahepatic bile ducts (NIBD) were assessed. The miRNA ... Intrahepatic cholangiocarcinoma (ICC) is a high-grade malignant neoplasm originating from the small bile duct epithelium in the ... and is the second most common intrahepatic primary tumor after hepatocellular carcinoma (HCC). It comprises 5.4% of primary ... In this study, we analyzed the miRNA expression profiles in 63 patients with ICC and nine normal intrahepatic bile ducts (NIBD ...
Biliary cystadenomas are benign but potentially malignant cystic neoplasms, which classically contain mesenchymal stroma ... Hepatic Duct, Common*. Humans. Middle Aged. Ovarian Neoplasms / complications, diagnosis*, secondary, surgery. Tomography, X- ... Bile Duct Neoplasms / complications, diagnosis*, surgery. Cystadenoma / complications, diagnosis*, surgery. Female. ... Gastrointestinal Stromal Tumors / complications, diagnosis*, secondary, surgery. ...
... surgical management Evidence of surgical management of distal common bile duct cancer Evidence of surgical management of ... cystic neoplasms of the pancreas Classification of endocrine tumors of the pancreas Clinical manifestation of endocrine tumors ... John Wiley & Sons (2015) ISBN 978-0-470-67318-8 Histologic classification and tumor staging of pancreatic cancer What we know ... diagnostics of endocrine tumors of the pancreas Evidence of medical and radionuclide-targeted treatment of endocrine tumors of ...
A 72 year-old Japanese woman showed remarkable dilatation of the main pancreatic duct (MPD) in the distal region of the ... Fistula formation has been reported in intraductal papillary-mucinous neoplasms (IPMNs) with or without invasion of the ... Affected Organ; C: Common bile duct, D: Duodenum, S: Stomach. Pathological Diagnosis; pap: papillary carcinoma, muc: mucinous ... Baek et al and Watanabe et al reported the same phenomenon in mucinous cystic tumors (MCTs) [11, 12]. The mechanism of such ...
... common bile duct and a dilated main pancreatic duct in the absence of calculus suggests ampullary or pancreatic head neoplasm, ... Extension of the tumor beyond the margins of the pancreas, involvement of adjacent organs or the SMA, liver metastases, ascites ... an isolated pancreatic mass with or without dilatation of the bile and pancreatic ducts and combined bile-pancreatic duct ... The finding of a dilated main pancreatic duct in the body or tail but not in the head or neck suggests neoplasm, and finally, ...
... was first described by Chen et al in 2001 as a biliary papillary tumor associated with … ... Intraductal papillary neoplasm of the bile duct (IPNB) ... stepwise progression to carcinoma involves common molecular ... In terms of tumor location, 15/19 IPNBs (79%) developed in intrahepatic bile ducts, and 41/48 PCCs (85%) in the distal bile ... shape of tumor, appearance of mural nodules, duct dilatation at unaffected duct, and abnormal enhancement of the adjacent bile ...
  • A minority arises from the islet cells and is classified as a neuroendocrine tumor. (addexbio.com)
  • This is due to advanced local tumor extension (40%) or the presence of distant metastatic disease (40%) mostly due to liver metastases of para-aortic lymphadenopathy. (radiologyassistant.nl)
  • In patients with a longer life expectancy (e.g. patients with a small, but locally unresectable tumor without distant metastatic disease), a double bypass is generally also considered acceptable palliation. (radiologyassistant.nl)
  • The CT scan can be used to guide biopsy needles into areas of abdominal tumors to obtain tissue for laboratory analysis and to guide placement of catheters for drainage of intra-abdominal abscesses. (thefreedictionary.com)
  • After radiologic evaluation, an incisional biopsy was performed and then the mass was excised en bloc. (biomedsearch.com)
  • Only those patients who have higher than normal levels of CA19-9 tumor marker will be enrolled, which will serve as a surrogate marker in a manner alpha fetoprotein (AFP) has been used as a predictor of clinical response in HCC patients. (clinicaltrials.gov)
  • Serum-based assays are the most widely used tests for the detection of tumor markers in clinical settings. (sbirsource.com)
  • Since sarcomatoid carcinoma in the common bile duct (CBD) is rarely reported, the clinical course and prognosis after surgery are unclear. (kjco.org)
  • Laboratory findings the most common pre- lone on clinical practice guidelines and a wide variety of techniques (eg, double voiding, suprapubic pressure) can prove challenging as fre- 1. (wsradio.com)
  • As the clinical presentation, staging and treatment of other types of pancreatic neoplasms is distinctly different from adenocarcinomas, these are not discussed in this article. (radiologyassistant.nl)
  • Among the distal common bile duct carcinomas, the presence of poorly differentiated histology correlated with decreased survival in multivariate analysis, while labeling for p53 or Dpc4, margin status, lymph node status, and tumor dimension did not correlate significantly with survival. (unboundmedicine.com)
  • The Pediatric Surgery service evaluates and surgically treats enlarged and infected lymph nodes when appropriate from a variety of conditions which include infections (cat scratch, atypical mycobacteria, tuberculosis, staphylococcus, streptococcus, and a variety of other bacteria) , tumors (Hodgkin and non-Hodgkin lymphoma, metastases from other primary tumors), and idiopathic enlargement. (indiasurgerytour.com)
  • Zollinger-Ellison syndrome (ZES) is characterized by severe peptic ulcer disease that results from non-beta islet cell tumors, gastrinomas, of the gastrointestinal tract. (aetna.com)