Lipids
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Cholesterol
Cholesterol, HDL
Lipase
Lipoproteins
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
Lipoproteins, VLDL
A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Lipid Metabolism
Apolipoproteins B
Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
Cholesterol, LDL
Lipoprotein Lipase
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
Liver
Dietary Fats
Fatty Acids
Fatty Acids, Nonesterified
Hypolipidemic Agents
Chylomicrons
Lipolysis
The metabolic process of breaking down LIPIDS to release FREE FATTY ACIDS, the major oxidative fuel for the body. Lipolysis may involve dietary lipids in the DIGESTIVE TRACT, circulating lipids in the BLOOD, and stored lipids in the ADIPOSE TISSUE or the LIVER. A number of enzymes are involved in such lipid hydrolysis, such as LIPASE and LIPOPROTEIN LIPASE from various tissues.
Apolipoproteins
Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and LIPID METABOLISM. These proteins are synthesized mainly in the LIVER and the INTESTINES.
Apolipoprotein C-III
A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Insulin Resistance
Adipose Tissue
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Obesity
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Dyslipidemias
Apolipoproteins C
A group of apolipoproteins that can readily exchange among the various classes of lipoproteins (HDL; VLDL; CHYLOMICRONS). After lipolysis of TRIGLYCERIDES on VLDL and chylomicrons, Apo-C proteins are normally transferred to HDL. The subtypes can modulate remnant binding to receptors, LECITHIN CHOLESTEROL ACYLTRANSFERASE, or LIPOPROTEIN LIPASE.
Lipoproteins, HDL
A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.
Apolipoproteins A
Structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS), including APOLIPOPROTEIN A-I and APOLIPOPROTEIN A-II. They can modulate the activity of LECITHIN CHOLESTEROL ACYLTRANSFERASE. These apolipoproteins are low in atherosclerotic patients. They are either absent or present in extremely low plasma concentration in TANGIER DISEASE.
Lipoproteins, LDL
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
Fatty Liver
Metabolic Syndrome X
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Body Weight
Apolipoprotein B-100
Cholesterol, VLDL
Cholesterol which is contained in or bound to very low density lipoproteins (VLDL). High circulating levels of VLDL cholesterol are found in HYPERLIPOPROTEINEMIA TYPE IIB. The cholesterol on the VLDL is eventually delivered by LOW-DENSITY LIPOPROTEINS to the tissues after the catabolism of VLDL to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LDL.
Hyperlipidemia, Familial Combined
Phospholipids
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
Glycerol
Hyperlipoproteinemia Type IV
A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits.
Risk Factors
Cholesterol Esters
Diacylglycerol O-Acyltransferase
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Body Mass Index
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
Apolipoprotein B-48
A 241-kDa protein synthesized only in the INTESTINES. It serves as a structural protein of CHYLOMICRONS. Its exclusive association with chylomicron particles provides an indicator of intestinally derived lipoproteins in circulation. Apo B-48 is a shortened form of apo B-100 and lacks the LDL-receptor region.
Oleic Acid
Oleic Acids
Apolipoprotein A-I
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
Hypercholesterolemia
Apolipoproteins E
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
Cardiovascular Diseases
Dietary Carbohydrates
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
Oils
Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
Sterol Esterase
Fish Oils
Carrier Proteins
Fructose
Hyperlipoproteinemias
Emulsions
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
Cholesterol Ester Transfer Proteins
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Lipogenesis
Glucose
Bezafibrate
1-Acylglycerol-3-Phosphate O-Acyltransferase
PPAR alpha
Adipocytes
Niacin
Fats
The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed)
Gemfibrozil
Lipid Mobilization
LIPOLYSIS of stored LIPIDS in the ADIPOSE TISSUE to release FREE FATTY ACIDS. Mobilization of stored lipids is under the regulation of lipolytic signals (CATECHOLAMINES) or anti-lipolytic signals (INSULIN) via their actions on the hormone-sensitive LIPASE. This concept does not include lipid transport.
Reference Values
Coronary Disease
Angiopoietins
Esterification
The process of converting an acid into an alkyl or aryl derivative. Most frequently the process consists of the reaction of an acid with an alcohol in the presence of a trace of mineral acid as catalyst or the reaction of an acyl chloride with an alcohol. Esterification can also be accomplished by enzymatic processes.
Sterol Regulatory Element Binding Protein 1
Glucose Tolerance Test
Apolipoprotein C-II
A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Atherosclerosis
Waist Circumference
Arteriosclerosis
Abetalipoproteinemia
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features include defective intestinal lipid absorption, very low serum cholesterol level, and near absent LDL.
Stearoyl-CoA Desaturase
3-Hydroxybutyric Acid
Lipoprotein(a)
A lipoprotein that resembles the LOW-DENSITY LIPOPROTEINS but with an extra protein moiety, APOPROTEIN (A) also known as APOLIPOPROTEIN (A), linked to APOLIPOPROTEIN B-100 on the LDL by one or two disulfide bonds. High plasma level of lipoprotein (a) is associated with increased risk of atherosclerotic cardiovascular disease.
Ketone Bodies
Adiponectin
A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the white ADIPOSE TISSUE. Adiponectin modulates several physiological processes, such as metabolism of GLUCOSE and FATTY ACIDS, and immune responses. Decreased plasma adiponectin levels are associated with INSULIN RESISTANCE; TYPE 2 DIABETES MELLITUS; OBESITY; and ATHEROSCLEROSIS.
Carbon Isotopes
Leptin
Colipases
Cross-Sectional Studies
Body Composition
Receptors, LDL
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
Lipoproteins, IDL
A mixture of very-low-density lipoproteins (VLDL), particularly the triglyceride-poor VLDL, with slow diffuse electrophoretic mobilities in the beta and alpha2 regions which are similar to that of beta-lipoproteins (LDL) or alpha-lipoproteins (HDL). They can be intermediate (remnant) lipoproteins in the de-lipidation process, or remnants of mutant CHYLOMICRONS and VERY-LOW-DENSITY LIPOPROTEINS which cannot be metabolized completely as seen in FAMILIAL DYSBETALIPOPROTEINEMIA.
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Hyperlipoproteinemia Type III
An autosomal recessively inherited disorder characterized by the accumulation of intermediate-density lipoprotein (IDL or broad-beta-lipoprotein). IDL has a CHOLESTEROL to TRIGLYCERIDES ratio greater than that of VERY-LOW-DENSITY LIPOPROTEINS. This disorder is due to mutation of APOLIPOPROTEINS E, a receptor-binding component of VLDL and CHYLOMICRONS, resulting in their reduced clearance and high plasma levels of both cholesterol and triglycerides.
Energy Metabolism
Chromatography, Gas
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Diabetes Mellitus
Fatty Acids, Unsaturated
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Palmitic Acid
Metabolic Diseases
Hyperlipoproteinemia Type II
Adiposity
Hyperinsulinism
A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
Chromatography, Thin Layer
3T3-L1 Cells
Hyperlipoproteinemia Type I
Genotype
Oxidation-Reduction
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Diet, Fat-Restricted
Apolipoprotein A-II
The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.
Lipid Metabolism Disorders
Uric Acid
Fats, Unsaturated
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Ultracentrifugation
Fatty Acids, Omega-3
A group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon. These fatty acids are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.
Hepatocytes
Cocos
Rats, Zucker
Rats, Wistar
Rats, Sprague-Dawley
Simvastatin
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
C-Reactive Protein
Lipodystrophy
A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.
Lipid Metabolism, Inborn Errors
Eicosapentaenoic Acid
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Heparin
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Intra-Abdominal Fat
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Cross-Over Studies
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Hemoglobin A, Glycosylated
Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.
Sex Characteristics
Prospective Studies
Anthropometry
Hypertension
Mice, Obese
Muscle, Skeletal
Rats, Inbred Strains
Phenotype
Milk
Bile Acids and Salts
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
Thiazolidinediones
Anti-Obesity Agents
Hyperlipoproteinemia Type V
A severe type of hyperlipidemia, sometimes familial, that is characterized by the elevation of both plasma CHYLOMICRONS and TRIGLYCERIDES contained in VERY-LOW-DENSITY LIPOPROTEINS. Type V hyperlipoproteinemia is often associated with DIABETES MELLITUS and is not caused by reduced LIPOPROTEIN LIPASE activity as in HYPERLIPOPROTEINEMIA TYPE I .
PPAR gamma
Complement C3a
The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Double-Blind Method
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Alanine Transaminase
Apolipoprotein C-I
A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.
Analysis of Variance
Apolipoprotein E2
One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III.
Safflower Oil
An oily liquid extracted from the seeds of the safflower, Carthamus tinctorius. It is used as a dietary supplement in the management of HYPERCHOLESTEROLEMIA. It is used also in cooking, as a salad oil, and as a vehicle for medicines, paints, varnishes, etc. (Dorland, 28th ed & Random House Unabridged Dictionary, 2d ed)
Mice, Transgenic
Phosphatidylcholine-Sterol O-Acyltransferase
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43.
Obesity, Abdominal
Disease Models, Animal
Quantitative aspects in the assessment of liver injury. (1/12738)
Liver function data are usually difficult to use in their original form when one wishes to compare the hepatotoxic properties of several chemical substances. However, procedures are available for the conversion of liver function data into quantal responses. These permit the elaboration of dose-response lines for the substances in question, the calculation of median effective doses and the statistical analysis of differences in liver-damaging potency. These same procedures can be utilized for estimating the relative hazard involved if one compares the liver-damaging potency to the median effective dose for some other pharmacologie parameter. Alterations in hepatic triglycerides, lipid peroxidation, and the activities of various hepatic enzymes can also be quantitiated in a dose-related manner. This permits the selection of equitoxic doses required for certain comparative studies and the selection of doses in chemical interaction studies. The quantitative problems involved in low-frequency adverse reactions and the difficulty these present in the detection of liver injury in laboratory animals are discussed. (+info)Serum triglyceride: a possible risk factor for ruptured abdominal aortic aneurysm. (2/12738)
BACKGROUND: We aimed to determine the relationship between ruptured abdominal aortic aneurysm (AAA) and serum concentrations of lipids and apolipoproteins. METHODS: A cohort of 21 520 men, aged 35-64 years, was recruited from men attending the British United Provident Association (BUPA) clinic in London for a routine medical examination in 1975-1982. Smoking habits, weight, height and blood pressure were recorded at entry. Lipids and apolipoproteins were measured in stored serum samples from the 30 men who subsequently died of ruptured AAA and 150 matched controls. RESULTS: Triglyceride was strongly related to risk of ruptured AAA. In univariate analyses the risk in men on the 90th centile of the distribution relative to the risk in men on the 10th (RO10-90) was 12 (95% confidence interval [CI] : 3.8-37) for triglyceride, 5.5 (95% CI: 1.8-17) for apolipoprotein B (apoB) (the protein component of low density lipoprotein [LDL]), 0.15 (95% CI : 0.04-0.56) for apo A1 (the protein component of high density lipoprotein [HDL]), 3.7 (95% CI: 1.4-9.4) for body mass index and 3.0 (95% CI: 1.1-8.5) for systolic blood pressure. Lipoprotein (a) (Lp(a)) was not a significant risk factor (RO10-90 = 1.6, 95% CI: 0.6-3.0). In multivariate analysis triglyceride retained its strong association. CONCLUSION: Triglyceride appears to be a strong risk factor for ruptured AAA, although further studies are required to clarify this. If this and other associations are cause and effect, then changing the distribution of risk factors in the population (by many people stopping smoking and adopting a lower saturated fat diet and by lowering blood pressure) could achieve an important reduction in mortality from ruptured AAA. (+info)Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats. (3/12738)
The effects of garlic supplementation on triglyceride metabolism were investigated by measurements of the degree of thermogenesis in interscapular brown adipose tissue (IBAT), and noradrenaline and adrenaline secretion in rats fed two types of dietary fat. In Experiment 1, rats were given isoenergetic high-fat diets containing either shortening or lard with or without garlic powder supplementation (8 g/kg of diet). After 28 d feeding, body weight, plasma triglyceride levels and the weights of perirenal adipose tissue and epididymal fat pad were significantly lower in rats fed diets supplemented with garlic powder than in those fed diets without garlic powder. The content of mitochondrial protein and uncoupling protein (UCP) in IBAT, and urinary noradrenaline and adrenaline excretion were significantly greater in rats fed a lard diet with garlic powder than in those fed the same diet without garlic. Other than adrenaline secretion, differences due to garlic were significant in rats fed shortening, also. In Experiment 2, the effects of various allyl-containing sulfides present in garlic on noradrenaline and adrenaline secretion were evaluated. Administration of diallyldisulfide, diallyltrisulfide and alliin, organosulfur compounds present in garlic, significantly increased plasma noradrenaline and adrenaline concentrations, whereas the administration of disulfides without allyl residues, diallylmonosulfide and S-allyl-L-cysteine did not increase adrenaline secretion. These results suggest that in rats, allyl-containing sulfides in garlic enhance thermogenesis by increasing UCP content in IBAT, and noradrenaline and adrenaline secretion. (+info)The food matrix of spinach is a limiting factor in determining the bioavailability of beta-carotene and to a lesser extent of lutein in humans. (4/12738)
Carotenoid bioavailability depends, amongst other factors, on the food matrix and on the type and extent of processing. To examine the effect of variously processed spinach products and of dietary fiber on serum carotenoid concentrations, subjects received, over a 3-wk period, a control diet (n = 10) or a control diet supplemented with carotenoids or one of four spinach products (n = 12 per group): whole leaf spinach with an almost intact food matrix, minced spinach with the matrix partially disrupted, enzymatically liquefied spinach in which the matrix was further disrupted and the liquefied spinach to which dietary fiber (10 g/kg wet weight) was added. Consumption of spinach significantly increased serum concentrations of all-trans-beta-carotene, cis-beta-carotene, (and consequently total beta-carotene), lutein, alpha-carotene and retinol and decreased the serum concentration of lycopene. Serum total beta-carotene responses (changes in serum concentrations from the start to the end of the intervention period) differed significantly between the whole leaf and liquefied spinach groups and between the minced and liquefied spinach groups. The lutein response did not differ among spinach groups. Addition of dietary fiber to the liquefied spinach had no effect on serum carotenoid responses. The relative bioavailability as compared to bioavailability of the carotenoid supplement for whole leaf, minced, liquefied and liquefied spinach plus added dietary fiber for beta-carotene was 5.1, 6.4, 9.5 and 9.3%, respectively, and for lutein 45, 52, 55 and 54%, respectively. We conclude that the bioavailability of lutein from spinach was higher than that of beta-carotene and that enzymatic disruption of the matrix (cell wall structure) enhanced the bioavailability of beta-carotene from whole leaf and minced spinach, but had no effect on lutein bioavailability. (+info)Improvement of factor VII clotting activity following long-term NCPAP treatment in obstructive sleep apnoea syndrome. (5/12738)
Obstructive sleep apnoea syndrome (OSAS) is a very common disorder. Patients with OSAS are at an increased risk for cardiovascular events. It has also been reported that a 25% rise in factor VII clotting activity (FVIIc) is associated with a 55% increase in ischaemic heart disease death during the first 5 years. We examined the effects of nasal continuous positive airway pressure (NCPAP) treatment on FVIIc in patients with OSAS. FVIIc was investigated prospectively in 15 patients with OSAS before (mean +/- SEM apnoea and hypopnoea index (AHI) 61.5 +/- 4.2 and after (AHI 3.0 +/- 0.9) NCPAP treatment for immediate relief, at 1 month after treatment and at over 6 months. FVIIc levels gradually decreased after NCPAP treatment. After 6 months of NCPAP treatment, FVIIc levels had decreased significantly (before 141.1 +/- 11.7% vs. after 6 months 110.7 +/- 6.2%; p < 0.01). Six of the seven patients whose FVIIc levels were over 140% before the NCPAP treatment had FVIIc levels below 130% after 6 months or 1 year of NCPAP treatment. This decrease in FVIIc after long-term NCPAP treatment could improve mortality in OSAS patients. If patients, especially obese ones, present with high FVIIc of unknown origin, it would be prudent to check for OSAS. (+info)Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. (6/12738)
OBJECTIVE: To study possible associations between coronary heart disease and serological evidence of persistent infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus. DESIGN: Population based, case-control study, nested within a randomised trial. SETTING: Five general practices in Bedfordshire, UK. INDIVIDUALS: 288 patients with incident or prevalent coronary heart disease and 704 age and sex matched controls. RESULTS: High concentrations of serum IgG antibodies to H pylori were present in 54% of cases v 46% of controls, with corresponding results for C pneumoniae seropositivity (33% v 33%), and cytomegalovirus seropositivity (40% v 31%). After adjustments for age, sex, smoking, indicators of socioeconomic status, and standard risk factors, the odds ratios (95% confidence intervals) for coronary heart disease of seropositivity to these agents were: 1.28 (0.93 to 1.75) for H pylori, 0.95 (0.66 to 1.36) for C pneumoniae, and 1.40 (0.96 to 2. 05) for cytomegalovirus. CONCLUSIONS: There is no good evidence of strong associations between coronary heart disease and serological markers of persistent infection with H pylori, C pneumoniae, or cytomegalovirus. To determine the existence of moderate associations between these agents and disease, however, larger scale studies will be needed that can keep residual confounders to a minimum. (+info)Dietary control of triglyceride and phospholipid synthesis in rat liver slices. (7/12738)
1. The effect of dietary manipulation on the synthesis of triglycerides and phospholipids was investigated by determining the incorporation of labeled long-chain fatty acid or glycerol into these lipids in liver slices derived from normally fed, fasted, and fat-free refed rats. 2. Triglyceride synthesis was affected markedly by the dietary regime of the animal; the lowest rates were measured with fasted rats, and the highest ones with fat-free refed rats. 3. In contrast to triglyceride synthesis, phospholipid synthesis occured at virtually constant rates regardless of the dietary conditions. 4. Addition of large amounts of fatty acid to the incubation mixture resulted in a marked stimulation of triglyceride synthesis, whereas phospholipid synthesis was affected to a much smaller extent. 5. These results indicate that the synthesis of triglycerides and that of phospholipids are controlled independently, and that the availability of fatty acid in the cell contributes to the control of triglyceride synthesis. (+info)Extremely low values of serum leptin in children with congenital generalized lipoatrophy. (8/12738)
Congenital generalized lipoatrophy (CGL) is a syndrome with multiple clinical manifestations and complete atrophy of adipose tissue. The exact mechanism of this disease remains unknown. One hypothesis presupposes an abnormal development of adipocytes. Leptin, the adipocyte-specific product of the ob gene, acts as a regulatory factor of body weight. In children, as in adults, leptin levels are correlated with body mass index (BMI) and body fat mass. Some authors have demonstrated that adults with congenital or acquired generalized lipoatrophy have decreased leptin concentrations. In order to study serum leptin profile during childhood in this disease, we measured serum leptin concentrations in six children aged 5.5-11 years suffering from CGL, and investigated the relationship between metabolic parameters and the variations in leptin levels. Serum leptin concentrations (1.19+/-0.32 ng/ml (+/- S.D.)) were extremely low compared with those observed in normal children. No significant correlation was found with BMI, which is known to be one of the major determinants of serum leptin. Serum leptin values were significantly correlated with fasting insulin levels (r=0.83, P=0.024). In conclusion, extremely low leptin values measured in children with CGL could be regarded as one among other diagnostic parameters. However, the detectable levels observed in all of these children support the evidence that a small amount of body fat is likely to be present in these patients, despite complete subcutaneous lipoatrophy. Our data suggest that this small amount of adipose tissue could be metabolically active and, at least in part, sensitive to insulin. Further investigations are required to uncover the pathophysiological mechanisms of this syndrome, known to be commonly associated with insulin resistance. (+info)
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To Compare Mean Triglyceride, HDL And LDL Levels in Controlled Type-II Diabetes Mellitus Patients Using Oral Hypoglycemic Drugs...
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Thoracentesis
Triglyceride and cholesterol[edit]. Chylothorax (fluid from lymph vessels leaking into the pleural cavity) may be identified by ... A triglyceride level over 110 mg/dl and the presence of chylomicrons indicate a chylous effusion. The appearance is generally ... determining triglyceride and cholesterol levels, which are relatively high in lymph. ...
Vegetable oil
Uses of triglyceride vegetable oil[edit]. Uses in antiquity[edit]. Oils extracted from plants have been used since ancient ... Like animal fats, vegetable fats are mixtures of triglycerides.[1] Soybean oil, grape seed oil, and cocoa butter are examples ... Other significant triglyceride oils include: *Corn oil, one of the most common cooking oils. As of 2006, the US produced about ... The following triglyceride vegetable oils account for almost all worldwide production, by volume. All are used as both cooking ...
Lipid profile
This test is used to identify dyslipidemia (various disturbances of cholesterol and triglyceride levels), many forms of which ... Typically the laboratory measures only three quantities: total cholesterol; HDL; Triglycerides. From these three data LDL may ... According to Friedewald's equation: LDL = Total cholesterol - HDL - Triglycerides/5 Other calculations of LDL from those same ... Then Friedewald's equation mentioned above yields: VLDL = Triglycerides/5 The alternative calculations mentioned above may ...
Caprylic acid
Some studies have shown that medium-chain triglycerides (MCTs) can help in the process of excess calorie burning, and thus ... Rego Costa AC, Rosado EL, Soares-Mota M (2012). "Influence of the dietary intake of medium chain triglycerides on body ... St-Onge, MP; Jones, PJ (2002). "Physiological effects of medium-chain triglycerides: potential agents in the prevention of ... Clegg, M. E. (2010). "Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise ...
Alcohol (drug)
monographs.iarc.fr "Triglycerides". American Heart Association. Archived from the original on 27 August 2007. Retrieved 4 ... Frequent drinking of alcoholic beverages is a major contributing factor in cases of elevated blood levels of triglycerides. ...
Hypertriglyceridemia
... is the presence of high amounts of triglycerides in the blood. Triglycerides are the most abundant fatty ... The word hypertriglyceridemia uses combining forms of hyper- + triglyceride + -emia, thus corresponding to "high triglyceride ... that hydrolyzes triglycerides in lipoproteins, leads to elevated levels of triglycerides in the blood. Lysosomal acid lipase ... The normal triglyceride level is less than 150 mg/dL (1.7 mmol/L). Once diagnosed, other blood tests are usually required to ...
Melon (cetacean)
triglycerides 47-51. 41-46. 45 Sperm whale[edit]. The analogous structure in the sperm whale is traditionally called "the junk ... The melon of pilot whales (Globicephala) is a mixture of wax esters and triglycerides. The inner core of the melon is about 33 ... The melon is a mixture of triglycerides and wax esters. The exact composition varies throughout the melon. Typically, the inner ... Litchfield, Carter; Ackman, R. G.; Sipos, J. C.; Eaton, C. A. (September 1971). "Isovaleroyl triglycerides from the blubber and ...
Short-term effects of alcohol consumption
Alcohol and postprandial triglyceridesEdit. Alcohol taken with a meal increases and prolongs postprandial triglyceridemia. This ... meaning that fasting triglycerides concentration is lower in people who drink 10-20 g/alcohol a day compared to people who ...
Nile red
In triglycerides (a neutral lipid), Nile red has an excitation maximum of about 515 nm (green), and emission maximum of about ... "Fluorescence SpectraViewer - Nile Red triglycerides". Thermo Fisher Scientific. 17 May 2017. Retrieved 6 March 2020. " ...
Fatty acid ester
Dietary fats are chemically triglycerides. Glycerol esters of fatty acids occur as colorless to brown powders, flakes, coarse ... When the alcohol component is glycerol, the fatty acid esters produced can be monoglycerides, diglycerides, or triglycerides. ...
Glossary of biology
Cholesterol and triglycerides are lipids. lipoprotein A biochemical assembly that contains both proteins and lipids, bound to ...
Isotretinoin
The compound 13-cis retinoic acid was first studied in the 1960s at Roche Laboratories in Switzerland by Werner Bollag as a treatment for skin cancer. Experiments completed in 1971 showed that the compound was likely to be ineffective for cancer and, surprisingly, that it could be useful to treat acne. However, they also showed that the compound was likely to cause birth defects, so in light of the events around thalidomide, Roche abandoned the product. In 1975, Gary Peck and Frank Yoder independently rediscovered the drug's use as a treatment of cystic acne while studying it as a treatment for lamellar ichthyosis, and published that work. Roche resumed work on the drug. In clinical trials, subjects were carefully screened to avoid including women who were or might become pregnant. Roche's New Drug Application for isotretinoin for the treatment of acne included data showing that the drug caused birth defects in rabbits. The FDA approved the application in 1982. Scientists involved in the ...
Prediabetes
It also is necessary for transport of amino acids, glycogen formation in the liver and skeletal muscles, triglyceride formation ... dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension."[2] It is thus a metabolic diathesis or ...
Congenital generalized lipodystrophy
... and high serum levels of triglycerides. Genetic testing can also confirm the disease, as mutations in the AGPAT2 gene is ...
Backbone chain
ISBN 978-1-118-91840-1.V Cox RA, García-Palmieri MR (1990). "31 Cholesterol, Triglycerides, and Associated Lipoproteins". In ...
Butterfat
... is mainly composed of triglycerides. Each triglyceride contains three fatty acids. Butterfat triglycerides contain ... by lowering total LDL and triglyceride levels. A study by the US Department of Agriculture showed that vaccenic acid raises ...
Feline cognitive dysfunction
ISBN 978-1-4649-6435-0. "Cats and Dietary Medium-Chain Triglycerides". Retrieved 2018-12-16. Curtis W. Dewey; Ronaldo C. da ... medium-chain triglycerides (can improve brain energy metabolism and decrease the amyloid protein buildup that results in brain ...
Hyperlipidemia
The elevated triglyceride levels (>5 mmol/l) are generally due to an increase in very low density lipoprotein (VLDL), a class ... Triglyceride level is an independent risk factor for cardiovascular disease and/or metabolic syndrome. Food intake prior to ... This form is due to high triglyceride level. Other lipoprotein levels are normal or increased a little. Treatment include diet ... The high VLDL levels are due to overproduction of substrates, including triglycerides, acetyl-CoA, and an increase in B-100 ...
Diglyceride
Because triglycerides cannot be absorbed by the digestive system, triglycerides must first be enzymatically digested into ... triglyceride), which is formed in the addition of a third fatty acid to the diacylglycerol under the catalysis of diglyceride ... transport in the blood and storage Lipid Monoglyceride Triglyceride IUPAC, Compendium of Chemical Terminology, 2nd ed. (the " ... Industrial production is primarily achieved by a glycerolysis reaction between triglycerides and glycerol. The raw materials ...
Coronary artery disease
High blood triglycerides may play a role. High levels of lipoprotein(a), a compound formed when LDL cholesterol combines with a ... Kannel WB, Vasan RS (July 2009). "Triglycerides as vascular risk factors: new epidemiologic insights". Current Opinion in ...
Grace Oladunni Taylor
Taylor, G. O. (1971). Serum triglycerides and fatty acids in kwashiorkor. The American journal of clinical nutrition, 24(10), ... Taylor, Grace Oladunni (1971-10-01). "Serum triglycerides and fatty acids in kwashiorkor". The American Journal of Clinical ...
Ucuhuba seed oil
ISBN 0-8493-9688-3, p. 86 Culp, T. W.; Harlow, R. D.; Litchfield, Carter; Reiser, Raymond (1965). "Analysis of triglycerides by ...
Fish oil
There are various prescription fish oil products that have been approved and permitted by the FDA for increasing triglyceride ... Prescription fish oil products having DHA raise up the LDL-C levels to reduce triglycerides, like fibrates. Heart experts ... 2018). "Assessment of omega-3 carboxylic acids in statin-treated patients with high levels of triglycerides and low levels of ... Prescription fish oils might only help when triglycerides reach a specific upper level. Prescription fish oil pills, capsules ...
Alcoholic liver disease
Subsequently, the higher levels of fatty acids signal the liver cells to compound it to glycerol to form triglycerides. These ... triglycerides accumulate, resulting in fatty liver. Alcoholic hepatitis is characterized by the inflammation of hepatocytes. ...
Fish oil (medical use)
Fish oil triglycerides was approved for use in the United States on July 27, 2018, and is available to patients on the US ... Although the use of fish oil triglycerides in children in the United States is experimental, the use of it in adults in Europe ... Fish oil triglycerides have also been associated with reduced mortality and antibiotic use during hospital stays. ... In European studies, fish oil triglycerides have been associated with a reduction in psoriasis, when contrasted to ...
Hypocholesterolemia
Marini A, Carulli G, Azzarà A, Grassi B, Ambrogi F (1989). "Serum cholesterol and triglycerides in hematological malignancies ...
Saltwater soap
Fats and oils are composed of triglycerides; three molecules of fatty acids are attached to a single molecule of glycerol. The ... In this reaction, the triglyceride fats are first hydrolyzed into free fatty acids, and then these combine with the alkali to ...
List of vegetable oils
Vegetable oils are triglycerides extracted from plants. Some of these oils have been part of human culture for millennia. ... Of interest as sources of medium chain triglycerides. Cupuaçu butter is closely analogous to cocoa, and is used to make white ...
Desvenlafaxine
... is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar.[5] It works by blocking the "reuptake" transporters for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotransmitters affected are serotonin (5-hydroxytryptamine) and norepinephrine (noradrenaline). It is approximately 10 times more potent at inhibiting serotonin uptake than norepinephrine uptake.[6]. ...
HRASLS3
Jaworski K, Sarkadi-Nagy E, Duncan RE, Ahmadian M, Sul HS (July 2007). "Regulation of triglyceride metabolism. IV. Hormonal ... AdPLA deficiency also demonstrated adverse effects, increasing ectopic triglyceride storage and insulin resistance. Liver ...
Medium Chain Triglycerides (MCTs) | Nutrition Review
MD and Jim English Medium Chain Triglycerides (MCTs) are a unique form of dietary fat that ... Medium-chain triglycerides (or MCTs) are fats that contain a few fatty acid tails of 6-12 carbon atoms in length. MCTs have ... Medium-chain triglycerides do not accumulate as fat in your body. How is this possible? This is because of their chain length. ... The medium-chain triglycerides that are found in coconut oil have a reduced length, and this allows them to be absorbed more ...
Triglycerides Test: MedlinePlus Medical Test
High triglyceride levels may put you at risk for heart disease. Learn more. ... A triglycerides test measures the amount of triglycerides in your blood. ... What is a triglycerides test?. A triglycerides test measures the amount of triglycerides in your blood. Triglycerides are a ... Very high triglyceride range: 500 mg/dL and above. Higher than normal triglyceride levels may put you at risk for heart disease ...
What Are Triglycerides? | Live Science
Triglycerides are the most common type of fat in the body. They are necessary for health but in excess amounts, they may be ... Normal triglyceride levels. You need some triglycerides to live healthily. Here are Wrights guidelines to triglyceride levels ... Triglycerides are a type of fat found in the blood. They are the most common type of fat in the body. Triglycerides are ... Dangers of high triglyceride levels. "If triglyceride levels are too high in the blood, they can cause plaque buildup in the ...
Triglycerides and Cholesterol
Question: Will fish oil lower triglycerides but increase bad cholesterol?. Dr. Hibberds Answer: Generally, fish oil is a ... Often triglycerides are reduced, and the HDL (good) cholesterol actually improves and LDL cholesterol decreases when fish oil ... I recommend that your cholesterol (HDL and LDL) and triglycerides be monitored for changes when fish oil is added as a ... At present, the American Heart Association recommends that people with high triglycerides take an omega-3 fatty acid supplement ...
Cholesterol and Triglycerides Blood Test Types
Cholesterol and triglyceride tests are blood tests that measure the total amount of fatty substances (cholesterol and ... Cholesterol and Triglycerides Tests. Test Overview. Cholesterol and triglyceride tests are blood tests that measure the total ... They carry triglycerides to your muscles for immediate use. Or they carry triglycerides to fat tissue for storage. ... Triglycerides are a type of fat the body uses to store energy and give energy to muscles. Only small amounts are found in the ...
Lowering Triglycerides - Mayo Clinic
4 Ways to Lower Triglycerides Quickly - wikiHow
Elevated triglycerides are worrisome because they can lead to an increased risk of heart disease and stroke. If you want to ... lower triglycerides quickly, you should make dietary changes like cutting out... ... Foods to Eat and Avoid and Exercises to Lower Triglycerides. Foods to Eat to Lower Triglycerides Quickly ... "Good advice on lowering triglycerides. Learned what to eat, take and do in lowering my triglycerides. Very helpful. Thank you." ...
How to Lower Your Triglycerides
... and learn about the drawbacks of having high triglyceride levels, along with what steps you can do to address this issue. ... and learn about the drawbacks of having high triglyceride levels, along with what steps you can do to address this issue. ... Q: What are foods high in triglycerides?. A: High-triglyceride foods you shouldnt include in your diet are alcohol,96 sugar,97 ... What are triglycerides?. Triglycerides are glycerol molecules found in your blood, with three fatty acids bound to them,3 and ...
What are triglycerides? | Reference.com
The body changes any calories it doesnt need immediately into triglycerides, which go into the fat cells for... ... Triglycerides are a form of fat appearing in the bloodstream, according to Mayo Clinic. ... Triglycerides generally respond quickly to changes in lifestyle and diet. People who fail to lower their high triglyceride ... Triglycerides are a form of fat appearing in the bloodstream, according to Mayo Clinic. The body changes any calories it ...
How to Lower High Triglycerides
Learn the range of normal triglyceride levels, what causes high triglycerides, how to reduce triglycerides and how to avoid ... Triglyceride levels need to be kept in check for good health, but you need to know how to lower triglycerides first. ... What Are Normal Triglyceride Levels? Triglyceride Ranges. Getting the right amount of triglycerides is important to your ... Learn Your Triglyceride Range: Go to the Doctor.. Its hard to know how much you need to do to reduce triglycerides if you ...
Triglycerides - Celiac.com
My triglycerides are practically non-existant and I see from a search of the site that others have commented on both low and ... Yes, very low triglycerides, in the absence of a super low-carb diet, is a sign that you are still not absorbing well. A year ... Triglycerides By [email protected], August 21, 2012. in Post Diagnosis, Recovery & Treatment of Celiac Disease ... My triglycerides are practically non-existant and I see from a search of the site that others have commented on both low and ...
Triglycerides - definition of triglycerides by The Free Dictionary
triglycerides synonyms, triglycerides pronunciation, triglycerides translation, English dictionary definition of triglycerides ... triglycerides. Translations. English: triglycerides n., pl. triglicéridos, combinación que resulta de una molécula de glicerol ... triglycerides. Also found in: Thesaurus, Medical, Financial, Acronyms, Encyclopedia, Wikipedia.. Related to triglycerides: ... Triglycerides - definition of triglycerides by The Free Dictionary https://www.thefreedictionary.com/triglycerides ...
How to Lower Cholesterol and Triglycerides (with Pictures)
How to Lower Cholesterol and Triglycerides. Many people try to lower their cholesterol at some point. To improve your ... Your HDL level should be 60 mg/dL or higher while your normal triglyceride blood levels should be less than 200 mg/dL.[32][33] ... Avoid trans fats in your diet. Trans fats are artificially produced fats that raise LDL cholesterol and triglyceride levels. ... Include an omega-3 supplement. To lower your LDL and triglycerides while increasing your HDL, take a supplement (if you dont ...
EWG Skin Deep® | What is C10-18 TRIGLYCERIDES
What causes high triglycerides? | Reference.com
High triglyceride levels are caused by lifestyle and health conditions, including obesity, poorly controlled diabetes, ... Triglycerides are a kind of fat in the bloodstream that are usually used to provide energy, but too many can cause health ... Triglyceride levels of less than 150 are normal, less than 200 are borderline high, less than 500 are high and levels 500 and ... What are some ways to lower triglycerides?. A: Exercise, weight loss, and reducing saturated fats and alcohol consumption can ...
Triglycerides and HDL Cholesterol | Diabetes Care
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 98: ... TRIGLYCERIDES, HDL CHOLESTEROL, AND CARDIOVASCULAR RISK. *DO WE NEED DRUGS TO REDUCE TG AND/OR INCREASE HDL CHOLESTEROL LEVELS? ... Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 1997; 40: 454- 462. ... Role of triglyceride-rich lipoproteins and hepatic lipase in determining the particle size and composition of high density ...
Triglycerides - Understand the Test & Your Results
A triglycerides test is used as part of a lipid profile to predict your risk of developing heart disease and to help make ... Triglycerides are a form of fat and a major source of energy for the body. ... Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in ... In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides ...
Triglyceride level: MedlinePlus Medical Encyclopedia
The triglyceride level is a blood test to measure the amount of triglycerides in your blood. Triglycerides are a type of fat. ... The triglyceride level is a blood test to measure the amount of triglycerides in your blood. Triglycerides are a type of fat. ... Your body makes some triglycerides. Triglycerides also come from the food you eat. Extra calories are turned into triglycerides ... Triglycerides are usually measured together with other blood fats. Often it is done to help determine your risk of developing ...
RhymeZone: triglyceride definitions
Articles, tagged with "triglycerides"
How to lower high triglycerides: Calories, fats, and carbs
Triglycerides are essential for health, but high levels increase the risk of certain diseases. Learn how to lower triglyceride ... Humans store extra calories in the form of triglycerides, which are the most common type of fat in the body. ... Importance of triglyceride levels. If a person's triglyceride levels are too high, they have a higher risk of certain ... to develop high triglyceride levels under certain circumstances.. If tests show that a person's triglyceride levels are ...
How to lower high triglycerides: Calories, fats, and carbs
Triglycerides are essential for health, but high levels increase the risk of certain diseases. Learn how to lower triglyceride ... Humans store extra calories in the form of triglycerides, which are the most common type of fat in the body. ... Triglyceride levels can also rise during pregnancy.. 9. Drugs to lower triglycerides. If other measures do not work, a doctor ... Importance of triglyceride levels. If a persons triglyceride levels are too high, they have a higher risk of certain diseases ...
Cooking For High Triglycerides by Jonathan Campbell (Paperback) - Lulu
Buy Cooking For High Triglycerides by Jonathan Campbell (Paperback) online at Lulu. Visit the Lulu Marketplace for product ... Cooking For High Triglycerides What are high triglycerides? What foods are sate to eat? What foods are not safe to eat? Inside ... According to the latest dietary information the follow are the requirments for a triglyceride friendly diet. Less then 200mg of ... along with 160 recipes aimed at lowering your cholesterol triglycerides, LDL cholesterol, as well as raising your HDL ...
Triglyceride Assessment - Are You Taking Care of Your Triglycerides?
Take this WebMD assessment to learn how triglyceride levels can affect your heart health and what you can do to lower your risk ... of Your Triglycerides?. Get Started Answer a few questions about. your lifestyle and health history.. Youll get:. *A ... Medscape: "What are the Causes of Increased Triglycerides?". West Virginia Department of Health and Human Services: "Obesity ... Palo Alto Medical Foundation: "Dietary Guidelines for Reducing Triglycerides.". National Institute on Alcohol and Alcoholism: " ...
Decrease Sugar Intake to Lower Triglycerides - Cholesterol
Sugar has a direct impact on triglyceride levels. Elevated triglycerides can cause your total cholesterol to be greater than ... Limiting sugar intake is essential if you are working to lower triglycerides . ... Limiting sugar intake is essential if you are working to lower triglycerides . Sugar has a direct impact on triglyceride levels ... Elevated triglycerides can cause your total cholesterol to be greater than 200 mg/dl. ...
Elevated Triglycerides, Medication Issue?? - Heart Disease - MedHelp
Triglycerides: About, Normal & High Levels, Risks & Treatment
Learn what causes high triglyceride levels and how to lower them. ... If the level of triglycerides in your blood is elevated, it ... Are low triglyceride levels a cause for concern?. Because low triglycerides are typically not cause for concern, theres not a ... Learn more about triglycerides, including what causes high triglyceride levels and how to lower them. ... Being concerned about high triglyceride levels isnt uncommon. But should you be worried if you have low triglycerides? Well ...
High Triglycerides Linked to Stroke | Medpage Today
Elevated nonfasting triglycerides -- but not cholesterol levels -- were associated with an increased risk of ischemic stroke, a ... High Triglycerides Linked to Stroke. Elevated nonfasting triglycerides -- but not cholesterol levels -- were associated with an ... And for men, the hazard ratio for those with the highest levels of triglycerides was 2.3 (95% CI 1.2 to 4.3, P for trend =0.001 ... Elevated nonfasting triglycerides -- but not cholesterol levels -- were associated with an increased risk of ischemic stroke, a ...
Cholesterol: High Triglyceride Foods to Avoid
Lower triglyceride levels and reduce cholesterol by eating foods that promote heart health. Reduce your intake of fat and sugar ... High triglycerides increase the risk of heart disease. ... Cholesterol: High Triglyceride Foods to Avoid. Sources: IMAGES ... Lower triglycerides by steering clear of sugar-sweetened beverages. Have some water with a squeeze of lemon juice or a splash ... Table sugar is not the only kind of sugar you need to be wary of when you have high triglycerides. Honey and maple syrup can ...
Triglyceride | Define Triglyceride at Dictionary.com
Triglyceride definition, an ester obtained from glycerol by the esterification of three hydroxyl groups with fatty acids, ... triglyceride. in Science. triglyceride. [trī-glĭs′ə-rīd′]. *Any of a class of organic compounds that are esters consisting of ... triglyceride. in Medicine. triglyceride. (trī-glĭs′ə-rīd′). n.. *. .css-10rk44a{font-size:15px;line-height:24px;}.css-10rk44a . ... triglyceride. noun. *any ester of glycerol and one or more carboxylic acids, in which each glycerol molecule has combined with ...
Elevated triglyceride levelsFatsMedium Chain TriglycLevelsLipidsHypertriglyceridemiaFatty acidsAlcoholBloodstreamLiverTreatment for high triglyceridesDietReduce triglyceridesCoronary heart dCaloriesLipid panelBorderlineCirculate in the bAtherosclerosisMetabolic syndromeLevelLess than 150BloodObesityLipoproteinsExcessStrokeGlycerolCardiovascular diseaseDiabetesPancreatitisHeart disease2017Raise triglyceridesSerum triglyceridesBodyHigh triglycerides and lowWays to lower triglyceridesCauses of high triglyceridesHealthyRiskCarbohydratesHelp lower your triglyceridesAmount of triglyceridesHelps lower triglycerides
Elevated triglyceride levels11
- Overall, the treatment of elevated triglyceride levels focuses on increased exercise and changes in the diet. (medlineplus.gov)
- Very recently, other researchers have also shown that some people with elevated triglyceride levels carry mutations in their GPIHBP1 gene. (redorbit.com)
- Elevated triglyceride levels may be a risk factor for atherosclerosis . (rxlist.com)
- Highly elevated triglyceride levels may also cause fatty liver disease and pancreatitis . (rxlist.com)
- Elevated triglyceride levels are a risk factor for atherosclerosis, the narrowing of arteries with the buildup of fatty plaques that may lead to heart attack , stroke , and peripheral artery disease . (rxlist.com)
- What do elevated triglyceride levels mean? (rxlist.com)
- About one−third of U.S. adults have elevated triglyceride levels. (thedoctorwillseeyounow.com)
- While elevated triglyceride levels may occur due to metabolic reasons, they're most often caused by diet. (thedoctorwillseeyounow.com)
- Elevated triglyceride levels may lead to pancreatitis, or inflammation of the pancreas. (chemocare.com)
- There are often times no symptoms of hypertriglyceridemia, unless you develop pancreatitis from your elevated triglyceride levels. (chemocare.com)
- Our results indicate that those participants with progressing diabetic neuropathy exhibited significantly elevated triglyceride levels and deficits in peroneal motor NCV at baseline. (diabetesjournals.org)
Fats45
- If you eat more calories than you burn off, especially calories from carbohydrates and fats, you may get high triglyceride levels in your blood. (medlineplus.gov)
- A lipid profile is a test that measures the level of fats in your blood, including triglycerides and cholesterol , a waxy, fatty substance found in every cell of your body. (medlineplus.gov)
- A diet that includes monounsaturated fats found in plants, such as olive oil, and fish high in omega-3 fatty acids, such as salmon, can help reduce triglyceride levels. (livescience.com)
- Most of the fats we eat, such as natural oils - both polyunsaturated and monounsaturated - animal fats and trans fats, are triglycerides. (livescience.com)
- While both healthy and unhealthy fats contribute to triglyceride levels, trans fats like margarine and saturated fats like fatty red meats, poultry skin, lard and some full-fat dairy products can elevate triglyceride levels more than leaner cuts of meat and unsaturated fats like olive oil, avocados, nuts and low-fat dairy products. (livescience.com)
- Healthy fats are also a great dietary addition as these help to stabilize blood sugar and can in turn help to lower triglycerides. (wikihow.com)
- People who generally eat more calories than they burn, particularly such calories as fats and carbohydrates, commonly end up suffering from high triglycerides. (reference.com)
- These triglycerides are fats that are important for your body, but too many of them can hurt your heart and lead to other health problems. (rxlist.com)
- Triglyceride fats can come from the food we eat. (rxlist.com)
- Trans fats are artificially produced fats that raise LDL cholesterol and triglyceride levels. (wikihow.com)
- These monounsaturated fats can lower bad cholesterol and triglycerides. (wikihow.com)
- Exercise, weight loss, and reducing saturated fats and alcohol consumption can lower triglyceride levels. (reference.com)
- Triglycerides are usually measured together with other blood fats. (medlineplus.gov)
- When a person eats more calories than their body needs, it stores these extra calories in the form of triglyceride fats. (medicalnewstoday.com)
- Choosing healthful fats may help reduce triglyceride levels. (medicalnewstoday.com)
- Trans fats and saturated fats raise triglyceride levels, so people should try to replace them wherever possible. (medicalnewstoday.com)
- Unsaturated fats , especially polyunsaturated fats (PUFAs), can help lower triglyceride levels. (medicalnewstoday.com)
- Doctors recommend that you watch your intake of fat when you have high triglycerides, especially saturated and trans fats. (medicinenet.com)
- You will get all the benefits of omega-3 fatty acids in fish without the downside of additional fats that may contribute to high triglyceride levels. (medicinenet.com)
- In addition to increasing triglycerides, diets high in saturated fats such as those found in coconut products increase total cholesterol and bad LDL cholesterol. (medicinenet.com)
- Triglycerides are the chief lipids constituting fats and oils and function to store chemical energy in plants and animals. (dictionary.com)
- Although triglycerides are stored in fats, they can be seen as stored energy sources. (home-remedies-for-you.com)
- When diets are too high on fats, the triglyceride levels become too high. (home-remedies-for-you.com)
- Your body gets triglycerides from fats in the foods you eat and also makes them from other types of foods, like carbohydrates. (drugs.com)
- Triglycerides are molecules found in vegetable and animal fats. (livestrong.com)
- Medium-chain triglycerides are fats that come from coconut oil, palm oil, and butter. (epnet.com)
- Most natural fats contain a complex mixture of individual triglycerides. (wikipedia.org)
- Triglycerides are the main ingredient in vegetable oils and animal fats . (rxlist.com)
- Triglycerides (TG) are fats found in the blood. (pcna.net)
- If you have very high or extremely high triglycerides, you may need to keep your total fat intake very low or eat only certain kinds of fats. (pcna.net)
- However, if you consume excess calories regardless from any source - carbohydrates, fats or protein - our body will transform these excess calories into triglycerides for storage as body fat. (healthcastle.com)
- The body creates triglycerides by breaking down oil and fats with digestive enzymes. (home-remedies-for-you.com)
- Triglycerides are a type of glyceride that make up the main component of both animal fats and vegeta. (home-remedies-for-you.com)
- A. Triglycerides are fats (lipids) that move through the bloodstream and can be stored in body tissues. (harvard.edu)
- In this Minireview, we evaluate the use of biobased sources, particularly fatty acids and triglycerides from seed oils and animal fats, as fuels. (wiley.com)
- Fatty acids are simply chains of carbon and hydrogen that can join together to form larger molecules such as triglycerides, sterols, saturated and unsaturated fats which will interact in our bodies. (fitday.com)
- The days when you only needed to know your total cholesterol level are gone," says Danya L. Dinwoodey, MD, a cardiologist at the Lahey Clinic in Burlington, Mass. "Think of your triglyceride level as one part of the total fats in your blood. (everydayhealth.com)
- To get the whole picture, you need to break down the total fats into good cholesterol, bad cholesterol, and triglycerides. (everydayhealth.com)
- Triglycerides are the form in which most fats exist in the body, including in your blood. (everydayhealth.com)
- Triglycerides are fats that circulate in the blood. (scienceblog.com)
- Healthy lifestyle choices, such as getting regular physical activity, losing weight, avoiding sugar and refined carbohydrates, limiting alcohol as well as choosing healthier fats from plants in place of saturated fats can help reduce triglycerides. (scienceblog.com)
- Fats exist in foods-and are usually stored in the body-as Triglycerides. (jrank.org)
- Here are two quick things to know about triglycerides: 1) The word is pronounced try-glis-er-ides and 2) they are fats, plain and simple. (davita.com)
- Following a kidney-friendly diet that is low in unhealthy fats and sugars is important for dialysis patients to maintain their triglycerides in a safe range. (davita.com)
- The purpose of this small, short pilot study is to determine the feasibility (e.g., recruitment, dose acceptance, retention) of a future longer trial comparing the effects of two types of omega-3 fats from fish oil on plasma triglycerides. (clinicaltrials.gov)
Medium Chain Triglyc11
- Medium Chain Triglycerides (MCTs) are a unique form of dietary fat that impart a wide range of positive health benefits. (nutritionreview.org)
- According to The Journal of Nutrition, medium-chain triglycerides (MCTs) have six to 12 carbon fatty acids, while long-chain triglycerides (LCTs) have more than a dozen carbon fatty acids. (mercola.com)
- Medium-chain triglycerides can be taken as an oil, pill, or powder. (epnet.com)
- There are no advised doses for medium-chain triglycerides. (epnet.com)
- It is likely safe to take medium-chain triglycerides in small doses for a short time, but stomach upset may happen. (epnet.com)
- Medium Chain Triglycerides (coconut fat) increase cognitive performance in Alzheimer's disease. (greenmedinfo.com)
- Omega-3 fatty acids and medium-chain triglycerides ameloriate high triglycerides in human subjects. (greenmedinfo.com)
- Dietary medium-chain triglycerides attenuate liver fat deposits in growing rats with protein malnutrition. (greenmedinfo.com)
- Medium-chain triglycerides (MCTs) are triglycerides with two or three fatty acids having an aliphatic tail of 6-12 carbon atoms, i.e., medium-chain fatty acids (MCFAs). (wikipedia.org)
- Medium-chain triglycerides are generally considered a good biologically inert source of energy that the human body finds reasonably easy to metabolize. (wikipedia.org)
- Due to their ability to be absorbed rapidly by the body, medium-chain triglycerides have found use in the treatment of a variety of malabsorption ailments. (wikipedia.org)
Levels223
- If you have high levels of both LDL (bad) cholesterol and triglycerides, you may be at an increased risk for a heart attack or stroke. (medlineplus.gov)
- Higher than normal triglyceride levels may put you at risk for heart disease. (medlineplus.gov)
- For this reason, scientists think that triglyceride levels may be an important measure of metabolic health. (livescience.com)
- Refined, simple carbohydrates and alcohol can also increase triglyceride levels, said Wright. (livescience.com)
- High triglyceride levels can also be a side effect of medications like beta blockers, birth control pills, steroids and diuretics, according to the Mayo Clinic . (livescience.com)
- If triglyceride levels are too high in the blood, they can cause plaque buildup in the arteries," explained Wright. (livescience.com)
- Scientists are not sure how or why triglycerides cause plaque buildup, but they do know that people with high levels of triglycerides are more likely to have high LDL levels. (livescience.com)
- According to the National Institutes of Health (NIH), women are especially at risk of heart disease if they have high triglyceride levels. (livescience.com)
- Scientists think that high triglyceride levels can also indicate other conditions that increase the risk of these diseases, such as obesity and metabolic syndrome. (livescience.com)
- Extremely high triglyceride levels can lead to acute pancreatitis, according to the Mayo Clinic. (livescience.com)
- The American Heart Association notes that more research is needed to be sure that high triglyceride levels are an independent risk for heart and other diseases. (livescience.com)
- Furthermore, a 2007 study published in Annals of Internal Medicine found that young men with the highest triglyceride levels had a four times greater risk of developing heart disease or having a stroke than similarly aged patients with the lowest triglyceride levels. (livescience.com)
- Lipoprotein analysis (lipoprotein profile or lipid profile ) measures blood levels of total cholesterol , LDL cholesterol , HDL cholesterol , and triglycerides . (webmd.com)
- This, in turn, is helpful to lower blood sugars as well as to lower blood "lipid" levels (including triglycerides). (wikihow.com)
- Although they act as energy reservoirs, 2 there are some health issues that may develop if your triglyceride levels are too high. (mercola.com)
- What causes high triglyceride levels? (mercola.com)
- Conventional medicine has led many to believe that increased fat intake is a precursor for high triglyceride levels 16 or hypertriglyceridemia. (mercola.com)
- He stresses that high triglyceride levels aren't caused by fat consumption, but rather by excessive sugar from net carbohydrates you consume. (mercola.com)
- To check if you have normal triglyceride levels or not, you'll need to take a blood test. (mercola.com)
- If your triglyceride levels are in the borderline high category or above, consult a doctor. (mercola.com)
- Exercise more often - Working out allows you to burn calories, 38 utilizing stored triglycerides and depleting their levels. (mercola.com)
- For people who need to reduce triglyceride levels, lifestyle alterations such as losing weight, increasing physical activity and starting a diet are the most common recommendations. (reference.com)
- People who fail to lower their high triglyceride levels run the risk of heart disease over the long term, states Mayo Clinic. (reference.com)
- In the following medically reviewed slides, we explain the role of triglycerides in the body and how you can work to reduce high triglyceride levels. (rxlist.com)
- When triglyceride levels are high, one of the major dangers is the threat of metabolic syndrome. (rxlist.com)
- But the wrong foods can send those triglyceride levels soaring. (rxlist.com)
- We'll take a detailed look at some of the foods to choose-and the ones to avoid - to make it easier for you to keep triglyceride levels in check. (rxlist.com)
- Although statins are effective in reducing heart attack risk, many users still often have high levels of triglycerides and go on to have heart attacks. (thefreedictionary.com)
- There is less evidence to support categorizing levels from 150 mg/dL to 1,000 mg/dL, as the exact level at which serum triglycerides may confer risk for cardiovascular disease is unknown. (thefreedictionary.com)
- Awareness and monitoring of triglycerides should occur right along with control of LDL and HDL cholesterol levels to help protect individual's cardiovascular health and minimize the risk for stroke," Dr. (thefreedictionary.com)
- High levels of triglycerides carry an increased risk of metabolic abnormalities, heart disease, and premature death. (thefreedictionary.com)
- High triglyceride levels are caused by lifestyle and health conditions, including obesity, poorly controlled diabetes, hypothyroidism, kidney disease, eating more calories than are burned and excessive alcohol consumption, according to WebMD. (reference.com)
- Triglyceride levels of less than 150 are normal, less than 200 are borderline high, less than 500 are high and levels 500 and over are very high, according to WebMD. (reference.com)
- Current guidelines call for an aggressive treatment strategy to reduce LDL cholesterol, blood pressure, and glucose levels in diabetic patients, but data concerning the management of high triglyceride (TG) levels and low HDL cholesterol levels remains inconclusive. (diabetesjournals.org)
- High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD) , although the reason for this is not well understood. (labtestsonline.org)
- Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and having medical conditions such as diabetes and kidney disease . (labtestsonline.org)
- Drugs to lower triglyceride levels may be used to prevent pancreatitis for levels above 500 mg/dL. (medlineplus.gov)
- The next time you reach into the fridge for a midnight snack - take heed: New research by Weizmann Institute scientists has shown that the time at which you eat your meals might have a profound effect on your liver triglyceride levels. (scienceblogs.com)
- Gemfibrozil Lopid - when administered together with a special diet - is effective in treating really high serum triglycerides levels that may lead to inflammation of the pancreas (a condition known as pancreatitis). (articlealley.com)
- The food that people eat, whether it is from animal or plant sources, can affect the levels of triglycerides in the blood. (medicalnewstoday.com)
- They all contribute to triglyceride levels in the body but do so in different ways. (medicalnewstoday.com)
- Triglycerides are important for health, but high levels increase the risk of heart disease , which is the leading cause of death in the United States. (medicalnewstoday.com)
- Lowering triglyceride levels and reducing other risk factors can decrease a person's likelihood of developing heart disease. (medicalnewstoday.com)
- There are many ways to reduce triglyceride levels safely. (medicalnewstoday.com)
- The best method may depend on the cause of the high triglyceride levels. (medicalnewstoday.com)
- One way to lower triglyceride levels in the blood is to consume fewer calories each day. (medicalnewstoday.com)
- According to the American Heart Association (AHA), a 5-10 percent weight loss can decrease triglyceride levels by 20 percent. (medicalnewstoday.com)
- A rise in triglyceride levels seems to accompany diets with a carbohydrate intake above 60 percent. (medicalnewstoday.com)
- Foods that contain a lot of simple sugars, especially refined fructose, can raise triglyceride levels. (medicalnewstoday.com)
- People should avoid added sugars to help reduce their triglyceride levels. (medicalnewstoday.com)
- A 24-year-old newly diagnosed male patient with diabetes presented with diabetic ketoacidosis (DKA) (pH 7.16, HCO3 6.0) and extreme hypertriglyceridemia (239.35 mmol/L). The diagnosis of DKA was delayed because of the apparent depression of the true serum glucose (to 11 mmol/L). He was treated with intravenous (IV) insulin and rehydration, which normalized his pH, HCO3, and triglyceride levels. (nih.gov)
- Sugar has a direct impact on triglyceride levels. (healthcentral.com)
- I have had some upper abdominal pressure and discomfort and was concerned for pancreatitis due to the Triglyceride levels. (medhelp.org)
- Learn more about triglycerides, including what causes high triglyceride levels and how to lower them. (healthline.com)
- High triglyceride levels (hypertriglyceridemia) are considered a high-risk factor for narrowing of the arteries ( atherosclerosis ) which can lead to stroke , heart attack , and peripheral arterial disease (PAD) . (healthline.com)
- If your triglyceride levels are high, you could be at high risk for pancreatitis (inflammation of the pancreas) and liver disease . (healthline.com)
- What are the causes and risks of high triglyceride levels? (healthline.com)
- Higher than normal triglyceride levels may put you at risk for arteriosclerosis (hardening of the arteries or thickening of the artery walls), heart attack, stroke, and heart disease. (healthline.com)
- If your triglyceride levels are high, you're at risk for pancreatitis and liver disease. (healthline.com)
- What's the best way to lower high triglyceride levels? (healthline.com)
- Are low triglyceride levels a cause for concern? (healthline.com)
- Elevated nonfasting triglycerides -- but not cholesterol levels -- were associated with an increased risk of ischemic stroke, a large Danish study found. (medpagetoday.com)
- Note that in this study, elevated nonfasting triglyceride levels were associated with increased risk of ischemic stroke in both women and men. (medpagetoday.com)
- Point out that the authors suggest that levels of nonfasting triglycerides should be included in guidelines. (medpagetoday.com)
- And for men, the hazard ratio for those with the highest levels of triglycerides was 2.3 (95% CI 1.2 to 4.3, P for trend =0.001) compared with those with the lowest levels, the researchers reported online in the Annals of Neurology . (medpagetoday.com)
- Yet, Benn and colleagues pointed out, "Elevated nonfasting triglycerides are markers of elevated levels of cholesterol in lipoprotein remnants thought to be atherogenic in the same way as low-density lipoprotein (LDL) cholesterol, by accumulation in the arterial wall. (medpagetoday.com)
- Analysis of the ischemic stroke outcome according to levels of nonfasting triglycerides revealed that, compared with levels below 1 mmol/L, risk rose increasingly beginning with levels from 1 to 1.99 mmol/L, when for women the hazard ratio was 1.2 (95% CI 0.9 to 1.7). (medpagetoday.com)
- The researchers acknowledged that it was "difficult to explain" why cholesterol did not appear to be associated with risk of ischemic stroke except in men with the highest levels, since increases in both cholesterol and triglycerides increase the risk of other disorders such as myocardial infarction. (medpagetoday.com)
- Our findings suggest that levels of nonfasting triglycerides should be included in guidelines as a marker of elevated levels of remnant lipoprotein cholesterol," they advised. (medpagetoday.com)
- The type and amount of carbohydrates you eat have a direct effect on your triglyceride levels. (medicinenet.com)
- These increase triglyceride levels. (medicinenet.com)
- Alcohol contains sugar and excess sugar increases triglyceride levels. (medicinenet.com)
- If you need to lower your blood triglyceride levels, ask your doctor if you can safely consume coconut and if so, how much. (medicinenet.com)
- Triglycerides in the body are not a bad thing unless their levels are high. (home-remedies-for-you.com)
- There are several factors which can cause high levels of triglycerides in the body. (home-remedies-for-you.com)
- diabetes and hyperthyroidism are also some of the factors which could affect the levels of triglycerides in the body. (home-remedies-for-you.com)
- If the triglyceride levels are too high, it is best to consult your doctor or health lower high triglycerides,high triglyceride treatment,high triglycerides symptoms,foods high triglycerides,care provider. (home-remedies-for-you.com)
- This is advised because very high levels of triglycerides can cause serious health complications such as a heart disease. (home-remedies-for-you.com)
- Even when the triglyceride levels are under control , it is best advised to follow a balanced diet, daily exercise, control over alcohol consumption as well as control over one's smoking habits. (home-remedies-for-you.com)
- Some of the assist is unrelated to triglycerides specifically, but good for cholesterol levels overall. (healthcentral.com)
- Is it any surprise that in a Stanford University study, the cholesterol levels of middle-age male runners were significantly lower (triglycerides included) than that of peers who didn't move their bodies much? (healthcentral.com)
- Avoiding sugary snacks and baked goods can help, too, by keeping your blood sugar levels more even, says Robert Greenfield, M.D., medical director of non-invasive cardiology and cardiac rehabilitation at MemorialCare Heart & Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA. "In fact, uncontrolled blood sugar is a major factor in causing high triglycerides. (healthcentral.com)
- As with cholesterol, triglyceride levels are measured in numbers. (drugs.com)
- Along with belly fat, high blood pressure, low levels of good cholesterol, and higher-than-normal levels of fasting blood sugar, triglyceride levels are one of the indicators of metabolic syndrome, according to the U.S. National Heart, Lung, and Blood Institute. (drugs.com)
- New findings reported in the July issue of Cell Metabolism, a Cell Press publication, are offering new leads as to why some people might suffer from high levels of triglycerides. (redorbit.com)
- Many patients with very high triglyceride levels don't have mutations in any of the genes with known links to the condition and some have no obvious abnormalities in LPL levels either. (redorbit.com)
- Being able to calculate triglyceride levels can help you know how to control your own. (livestrong.com)
- The Friedman formula is only reliable for triglyceride levels less than 400 mg/dL. (livestrong.com)
- What Is the Meaning of High Triglyceride Levels? (livestrong.com)
- High triglyceride levels can also contribute to health problems. (livestrong.com)
- Usually, triglycerides are tested in the form of a lipid panel that includes total cholesterol, HDL and LDL levels. (livestrong.com)
- High triglycerides are 201 mg/dl and up, and very high levels are anything over 500 mg/dl. (livestrong.com)
- There is no timetable to show when or if someone will have a heart attack, but having high levels of triglycerides is strongly associated with atherosclerosis, although high LDL cholesterol levels are believed to be the main cause of it. (livestrong.com)
- In addition, problems with uncontrolled type 2 diabetes, obesity and increased risks for heart disease are all associated with increased triglyceride levels. (livestrong.com)
- Women with triglyceride levels around 443 mg/dl were four times as likely to suffer a stroke as the women with the lower-than-89 mg/dl levels. (livestrong.com)
- The risk in men was similar for the mildly increased levels, but only showed two times the risk level for stroke as the triglyceride levels rose. (livestrong.com)
- While triglycerides lower than 150 mg/dl are normal, this study found the lowest risk levels were in those with triglycerides lower than 89 mg/dl. (livestrong.com)
- Studies done with laboratory rats suggest that supplementation of their diet with lipoic acid had a significant effect in lowering triglycerides, which along with cholesterol levels and blood pressure are one of the key risk factors in cardiovascular disease. (innovations-report.com)
- In the lab animals, supplements of lipoic acid lowered triglyceride levels up to 60 percent. (innovations-report.com)
- Until about 10 years ago, Moreau said, high blood levels of triglycerides - basically a form of fat - were not thought to be as significant as cholesterol at predicting atherosclerosis and heart disease. (innovations-report.com)
- That perspective has changed, he added, and most experts now see triglycerides as a third important risk factor for atherosclerosis, along with levels of "good" HDL and "bad" LDL cholesterol. (innovations-report.com)
- In this research, it was found that supplements of lipoic acid appeared to affect triglyceride levels through two pathways. (innovations-report.com)
- This is the first study that has identified the molecular targets by which lipoic acid can lower triglyceride levels, the researchers said, and to show the effect on liver enzymes resulting in less production of triglycerides. (innovations-report.com)
- Lipoic acid supplements have in various studies been shown to be an appetite suppressant, but control groups of laboratory animals were used in this research to ensure that lower triglyceride levels were not the result simply of less food intake. (innovations-report.com)
- The rats used in the experiment were obese to begin with, and developed higher triglyceride levels as the experiment proceeded and they aged - but the animals given lipoic acid fared much better. (innovations-report.com)
- As they grew from five weeks of age to nine weeks, the blood triglyceride levels doubled in rats given the supplement, but went up more than 400 percent in the other group not given supplements. (innovations-report.com)
- Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease. (innovations-report.com)
- Normal triglyceride levels are below 150. (fpnotebook.com)
- Triglyceride levels are decreased in hyperthyroidism, use of certain lipid-lowering drugs and malabsorption syndrome. (cdc.gov)
- High levels of serum triglycerides help determine the risk for coronary heart disease (CHD) and peripheral atherosclerosis. (cdc.gov)
- Triglycerides were recommended as a "secondary target" if levels exceeded 200 mg/dl, with nicotinic acid and fibrates useful pharmacologic approaches, and specific HDL cholesterol targets were not recommended ( 3 ). (diabetesjournals.org)
- High triglyceride levels can also be associated with diabetes , kidney disease , and the use of some medications. (rxlist.com)
- Normal triglyceride levels in the blood are less than 150 mg per deciliter (mg/dL). (rxlist.com)
- Triglyceride levels can be controlled to some extent by lifestyle modifications and, when necessary, medications. (rxlist.com)
- Alcohol consumption can raise triglyceride blood levels by causing the liver to produce more fatty acids. (rxlist.com)
- How are triglyceride levels measured? (rxlist.com)
- Triglyceride levels in the blood are measured by a simple blood test. (rxlist.com)
- Triglyceride and cholesterol levels are measured in the blood to provide a method of screening for this risk. (rxlist.com)
- High levels of triglycerides (greater than 200 mg/dl) are associated with an increased risk of atherosclerosis and therefore coronary artery disease and stroke . (rxlist.com)
- Returning triglyceride levels to normal may decrease the risk of heart attack, stroke , and peripheral artery disease. (rxlist.com)
- This may be all that is needed, but some people additionally require medications to lower triglyceride levels in the blood. (rxlist.com)
- Although your body needs cholesterol and triglycerides to keep you healthy, if you have abnormal levels of either in your bloodstream, it can lead to problems such as coronary heart disease and stroke. (thebody.com)
- HIV docs should test your cholesterol and triglycerides before prescribing an HIV regimen, repeat the tests within three to six months after you start the regimen, and then take new tests every year as long as your levels stay near normal. (thebody.com)
- Our rising triglyceride levels are not a good sign. (thedoctorwillseeyounow.com)
- High blood triglyceride levels dramatically increase a person's risk of stroke. (thedoctorwillseeyounow.com)
- In a recent Danish study, persons with the highest triglyceride levels were three to four times more likely to suffer an ischemic stroke than those with the lowest levels. (thedoctorwillseeyounow.com)
- Eating less total fat and exercising more are generally the best way to lower triglyceride levels. (thedoctorwillseeyounow.com)
- The U.S. National Health and Nutrition Surveys (NHANES) have shown that average triglyceride levels have risen about five fold in the last twenty−five years. (thedoctorwillseeyounow.com)
- The study also relied on a different way to measure triglyceride levels. (thedoctorwillseeyounow.com)
- Regular exercise at moderate to high levels helps to lower triglycerides. (pcna.net)
- If you take any of the triglyceride-lowering medicines, you will have a complete lipid panel blood test each year to check your cholesterol and triglyceride levels. (pcna.net)
- It is normal that our blood contains some levels of triglycerides, as they are often the by-products of fat being broken down and digested after a meal. (healthcastle.com)
- Age - your triglyceride levels will increase with age. (chemocare.com)
- Genetics - Increased triglyceride levels in the blood may be associated with certain genetic diseases or disorders, such as familial combined hyperlipidemia. (chemocare.com)
- However, there are some individuals that may never develop pancreatitis with high triglyceride levels, or some may develop pancreatitis with lower levels. (chemocare.com)
- Exercise, avoiding alcohol, fatty foods, and restricting calories are the primary treatments for elevated blood triglyceride levels. (chemocare.com)
- With higher levels, triglyceride-lowering medications may be used. (chemocare.com)
- Alcohol use will further increase your triglyceride levels, and may cause interactions with medications. (chemocare.com)
- A low-fat, high fiber diet may be suggested to lower triglyceride levels, and reduce your weight. (chemocare.com)
- Gemfibrozil - This medication will decrease cholesterol levels in your blood, and decrease the production of triglycerides from your liver. (chemocare.com)
- In some people with hyperlipidemia, however, high triglyceride levels are the primary problem. (stdavids.com)
- Furthermore, if triglyceride levels get high enough, the pancreas may become inflamed, causing a dangerous condition called pancreatitis. (stdavids.com)
- Diet, except when weight loss occurs, may not help, as a low-fat, high-carbohydrate diet can actually raise triglyceride levels. (stdavids.com)
- More than 2,000 people have participated in well-designed studies of fish oil for reducing triglyceride levels. (stdavids.com)
- Although not all studies have been positive, in a detailed review of 47 randomized trials, researchers concluded that fish oil is capable of significantly reducing triglyceride levels with no change in total cholesterol levels and only slight increases in HDL ("good") cholesterol and LDL ("bad") cholesterol. (stdavids.com)
- Fish oil has been studied for reducing triglyceride levels specifically in people with diabetes , and it appears to do so safely and effectively. (stdavids.com)
- According to some, but not all, studies, EPA may be more important than DHA for reducing triglyceride levels. (stdavids.com)
- In this video, Dr. Oz explains how your body accumulates triglycerides and why having higher than normal levels of triglycerides can increase your risk of heart disease. (sharecare.com)
- The most notable blood chemistry changes were in triglyceride levels in patients taking GS-0976. (medscape.com)
- At 12 weeks, triglyceride levels had dropped below 500 mg/dL in the four patients treated with fibrates or fish oil and in seven of the 12 patients not treated. (medscape.com)
- If you have prediabetes or diabetes, it's important to monitor your triglyceride level regularly because triglycerides will increase when you aren't properly maintaining your blood sugar levels. (healthline.com)
- Because of that, the numbers for triglycerides tends to be much higher than for HDL or LDL levels. (bellaonline.com)
- Usually the things that lower LDL levels also lower triglyceride levels. (bellaonline.com)
- In fact, the measurement of cardiovascular disease by tests uses the levels of triglyceride as a measure. (home-remedies-for-you.com)
- Since the brain uses carbohydrate sources as fuel, these two factors can cause the triglyceride levels to remain high and clog arteries of the heart. (home-remedies-for-you.com)
- Now, researchers from the Weizmann Institute of Science in Israel and the Sanford-Burnam Medical Resarch Institute in Florida have shown in mice that the timing of meals affects the levels of triglycerides in the liver. (the-scientist.com)
- Binge drinking of alcohol can cause dangerous spikes in triglyceride levels that can trigger inflammation of the pancreas ( pancreatitis ). (uwhealth.org)
- Estrogen therapy , which may be used for menopause symptoms, may also raise triglyceride levels. (uwhealth.org)
- In rare cases, people who have very high triglyceride levels may develop inflammation of the pancreas ( pancreatitis ), which can cause sudden, severe abdominal (belly) pain, loss of appetite, nausea and vomiting, and fever. (uwhealth.org)
- In many cases, people don't know that they have high triglycerides until they have a blood test called a lipoprotein analysis to check their cholesterol levels. (uwhealth.org)
- If your triglyceride levels are high, your doctor will also check for and treat other associated conditions that may be linked to high triglycerides. (uwhealth.org)
- You can use diet and lifestyle changes to lower triglyceride levels. (uwhealth.org)
- You may also take medicines to lower triglyceride levels. (uwhealth.org)
- Diet and lifestyle changes are the first steps you will take to lower triglyceride levels. (uwhealth.org)
- Pancreatitis in ethnic minorities is linked to very high levels of triglycerides and the risk is further increased by alcohol abuse and gallstones, according to a study published in the journal Endocrine Practice. (news-medical.net)
- Previous studies have found that severe levels of triglycerides are associated with pancreatitis, but the cutoff level has not been confirmed and there has been limited research on minority populations. (news-medical.net)
- The new study is the first to report on pancreatitis, due to severe levels of triglycerides, in a U.S. multiethnic minority population. (news-medical.net)
- Researchers performed a retrospective study of 1,157 adult patients in the Cook County Health & Hospitals System who had triglyceride levels higher than 1,000 mg/dL. (news-medical.net)
- Among patients with triglyceride levels higher than 2,000 mg/dL, there was a 4.3-fold increase in pancreatitis compared to patients with triglyceride levels between 1,000 and 1,999 mg/dL. (news-medical.net)
- Only 2 percent of patients with triglyceride levels below 2,000 mg/dL had pancreatitis, compared to 33.6 percent of patients who had triglyceride levels higher than 2,000 mg/dL and one other risk factor. (news-medical.net)
- The study's findings may help physicians assess the pancreatitis risk among patients with severe levels of triglycerides and decide on the urgency and intensity of managing the risk. (news-medical.net)
- This will modestly reduce triglyceride levels. (thebody.com)
- Reducing triglycerides cholesterol levels is a preoccupation with many of us nowadays, as basically, it is the key to heart health. (articleinsider.com)
- So you only need to think about reducing triglycerides cholesterol levels if you exceed the category for you personally. (articleinsider.com)
- Diet and exercise are definitely the best ways of all for reducing triglycerides cholesterol levels. (articleinsider.com)
- In addition to the measures listed on our other pages for reducing triglycerides cholesterol levels, you could also try green tea extract and grape seed extract. (articleinsider.com)
- A doctor can test the triglyceride levels in your blood to be sure they are at healthy levels. (fitday.com)
- Although treatment strategies for high triglyceride levels in the blood are well established, new clinical practice guidelines from the Endocrine Society released today in the Journal of Clinical Endocrinology and Metabolism recommend that more attention should be paid to the ways each person's unique history, physiology and lifestyle interact to affect risk. (ucdavis.edu)
- High triglyceride levels in the blood, or hypertriglyceridemia, greatly increase the likelihood of heart disease, but the causes of elevated levels and the degree of risk they pose can differ from person to person, the researchers stress. (ucdavis.edu)
- Berglund chaired the task force that assessed the current state of diagnosis and treatment for high blood triglyceride levels to set the new guidelines. (ucdavis.edu)
- Fatty foods, smoking and poor exercise, for example, all clearly contribute to risk for high triglyceride and high LDL cholesterol levels. (ucdavis.edu)
- But a diet high in simple sugars, such as from eating lots of white bread or sugary sodas, boosts triglyceride levels without affecting cholesterol. (ucdavis.edu)
- Similarly, alcohol is a boon to healthy levels of HDL ― the "good" cholesterol ― but alcohol consumption leads to higher triglyceride counts, the task force reports. (ucdavis.edu)
- Certain inherited genetic mutations also can contribute to overall risk, but lifestyle, diet and other factors appear to account for more cases of high triglyceride levels than do genetics, Berglund said. (ucdavis.edu)
- The task force pointed out that statins are effective against high triglyceride levels, but unusually high levels call for stronger medicines. (ucdavis.edu)
- Drugs known as fibrates are the first line of defense against excessive triglyceride levels, which can cause pancreatitis, an inflammation that poses severe health problems and is often fatal. (ucdavis.edu)
- A concern that is often under the radar is how drugs prescribed to treat other medical conditions can interact to raise blood triglyceride levels, the report stresses. (ucdavis.edu)
- For example, a drug called a bile acid sequestrant, prescribed for high LDL, can raise borderline triglyceride to potentially dangerous levels. (ucdavis.edu)
- Cholesterol levels have long been the focus of heart health, but high triglycerides affect about one-third of Americans. (everydayhealth.com)
- A recent article published in the Archives of Internal Medicine revealed that one-third of adults in the United States have borderline high triglyceride levels, and one in five have high triglyceride levels. (everydayhealth.com)
- Though high triglyceride levels have increased dramatically over the past 30 years, only 1.3 percent of people with high triglycerides are taking medication approved to lower triglyceride levels. (everydayhealth.com)
- These findings suggest that triglyceride levels need to get more attention. (everydayhealth.com)
- High triglyceride levels often go along with low HDL levels. (everydayhealth.com)
- The CDC researchers found that people with high triglyceride levels tended to be older and overweight, smoked more, and got less than 150 minutes of exercise per week. (everydayhealth.com)
- Many children and adolescents with high triglyceride levels also have other risk factors, such as high LDL levels or low HDL levels, or carry excess weight. (childrenshospital.org)
- Rarely, very high triglyceride levels are seen in children with genetic lipid disorders such as lipoprotein lipase deficiency. (childrenshospital.org)
- Prescription omega-3 fatty acid medication reduces triglyceride levels by 20-30% among the majority of people who require treatment for high triglyceride levels, according to a science advisory from the American Heart Association. (scienceblog.com)
- From our review of the evidence from 17 randomized, controlled clinical trials on high triglyceride levels, we concluded that treatment with 4 grams daily of any of the available prescription choices is effective and can be used safely in conjunction with statin medicines that lower cholesterol," said Ann Skulas-Ray, Ph.D., an author of the new science advisory published in the American Heart Association journal Circulation . (scienceblog.com)
- Some studies have shown that elevated levels of triglycerides (above 200 mg/dL) can lead to atherosclerosis (narrowing of the arteries) which increases the risk of heart attack and stroke. (scienceblog.com)
- In addition to cardiovascular risk, very high levels of triglycerides (above 500 mg/dL) can also cause pancreatitis, an inflammation of the pancreas. (scienceblog.com)
- Skulas-Ray points out that people with high triglyceride levels should not try to treat the condition themselves with non-prescription, omega-3 fatty acid fish oil supplements. (scienceblog.com)
- Currently, the FDA has approved prescription omega-3 fatty acid medications only for treating very high triglyceride levels above 500 mg/dL. (scienceblog.com)
- It is also important to treat or eliminate conditions such as poorly controlled type 2 diabetes, hypothyroidism and obesity that may contribute to high triglyceride levels before turning to medication. (scienceblog.com)
- Contrary to common perception, the formula that contains both EPA and DHA does not increase the "bad" form of cholesterol (LDL-C) among most people with high triglyceride levels (200-499 mg/dL). (scienceblog.com)
- However, when the drug is given to people with very high triglyceride levels at 500 mg/dL or greater, LDL-C may increase. (scienceblog.com)
- The panel's review found that the prescription omega-3 drugs are effective in reducing triglyceride levels regardless of whether people are on statin therapy. (scienceblog.com)
- Both of those conditions raise triglyceride levels. (scienceblog.com)
- Hypertriglyceridemia usually doesn't cause symptoms until triglycerides levels become excessively high-typically between 1,000 milligrams per deciliter (mg/dL) and 2,000 mg/dL. (verywellhealth.com)
- As levels near or exceed 5,000 mg/dL, which typically only occurs in people with genetic disorders such as familial dysbetalipoproteinemia and familial chylomicronemia, both of which cause extreme elevations in triglyceride and cholesterol levels. (verywellhealth.com)
- Elevated levels of triglycerides are a risk factor for developing metabolic syndrome and heart disease , the leading cause of death in the industrialized world. (nutritionfacts.org)
- Consuming processed sugars , especially in liquid form ( soda or juice ), may also cause a spike in triglyceride levels. (nutritionfacts.org)
- Beans and other legumes appear to be particularly effective at lowering triglyceride levels, though whether this is due to their fiber content or to specific phytonutrients has not yet been determined. (nutritionfacts.org)
- Decreasing stress through regular exercise and meditation and decreasing the intake of saturated fat, cholesterol, and processed sugars are lifestyle interventions that may help lower triglyceride levels. (nutritionfacts.org)
- Patients with very high triglyceride levels (above 1000 mg/dL) may develop pancreatitis . (emedicinehealth.com)
- A lipid panel measures total cholesterol , HDL cholesterol , LDL cholesterol , and triglyceride levels in the blood. (emedicinehealth.com)
- Lifestyle changes that include a healthy diet can help to lower both triglycerides and your cholesterol levels. (everydayhealth.com)
- In a 26-patient Phase II trial, patients with severely high levels of triglycerides taking Isis' drug alongside fibrates experienced 64% drop in triglycerides, and a 70% drop in apolipoprotein C-III (apoC-III), a component of 'bad' low-density lipoprotein. (pharmatimes.com)
- The findings are particularly pertinent given that high levels of triglycerides put patients at significant risk for serious conditions such as cardiovascular disease, diabetes and pancreatitis. (pharmatimes.com)
- The data comes hot on the heels of that released last month, showing that the drug cut levels of apoC-III by 88% and triglycerides by 77% in patients with high levels of triglycerides and diabetes. (pharmatimes.com)
- Recent research relating levels of triglycerides in the blood stream to heart attacks in human presents a sometime confusing picture but a mounting level evidence suggests that, along with other indicators, triglyceride levels can be used to predict heart attack risk, especially in women and diabetics. (jrank.org)
- Should carbohydrate intake be restricted in patients with hypertriglyceridemia (high triglyceride levels)? (medscape.com)
- Does Nutropin affect Cholesterol and Triglyceride levels in pediactric patients? (drugs.com)
- I want to know how Percocet affect my Triglyceride and Cholesterol levels? (drugs.com)
Lipids10
- Triglycerides and cholesterol both belong to the "fat family" (also called lipids) but have different functions, said Wright. (livescience.com)
- There are many types of lipids that have been discovered, 1 but one that has amassed interest is triglycerides. (mercola.com)
- It does not matter if it is carbohydrates, protein or fat -- if it's not immediately used for energy, it is stored and saved for a later time in the form of lipids, or triglycerides. (livestrong.com)
- Because they are insoluble in water, the triglycerides are transported with other more polar lipids. (cdc.gov)
- In triglyceride form, lipids cannot be absorbed by the duodenum. (wikipedia.org)
- Triglycerides belong to a group of fat-related substances called lipids. (stdavids.com)
- They found that 27 of the lipids exhibited circadian oscillations, and that of those lipids, the majority were phosphoinositides and triglycerides (TAG), which peaked around eight hours after "sunrise. (the-scientist.com)
- A variety of healthy foods will provide you with the lipids including fatty acids, sterols and triglycerides you need for health. (fitday.com)
- Although you may know what your total cholesterol level is and be aware of the difference between bad cholesterol and good cholesterol, you may not know that your triglyceride level is an equally important part of your blood lipids profile. (everydayhealth.com)
- Triglyceride-rich lipoproteins (TRLs) transport lipids in the bloodstream, where the fatty acid moieties are liberated by the action of lipoprotein lipase (LPL). (nih.gov)
Hypertriglyceridemia5
- The study met its primary objective showing CaPre to be safe and effective in reducing triglycerides in patients with mild to severe hypertriglyceridemia. (thefreedictionary.com)
- Furthermore, alcohol increases the synthesis of large VLDL particles in the liver, which is the main source of triglycerides in the hypertriglyceridemia associated with chronic excessive alcohol intake. (hindawi.com)
- Hypertriglyceridemia may be described as an excess of triglycerides in the blood. (chemocare.com)
- In addition, a slightly modified form of fish oil (ethyl-omega-3 fatty acids) has been approved by the FDA as a treatment for hypertriglyceridemia (high triglycerides). (stdavids.com)
- High triglycerides, (hypertriglyceridemia) is a medical condition in which more triglycerides than can be burned off or stored accumulate in the bloodstream. (verywellhealth.com)
Fatty acids22
- Triglycerides are glycerol molecules found in your blood, with three fatty acids bound to them, 3 and are considered the most common type of body fat. (mercola.com)
- C10-18 Triglycerides is a triester of glycerin and a mixture of normal and branched chainC10-18 fatty acids. (ewg.org)
- A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from tri- and glyceride). (wikipedia.org)
- In triglycerides, the hydroxyl groups of the glycerol join the carboxyl groups of the fatty acid to form ester bonds: HOCH2CH(OH)CH2OH + RCO2H + R′CO2H + R″CO2H → RCO2CH2CH(O2CR′)CH2CO2R″ + 3H2O The three fatty acids (RCO2H, R′CO2H, R″CO2H in the above equation) are usually different, as many kinds of triglycerides are known. (wikipedia.org)
- The chain lengths of the fatty acids in naturally occurring triglycerides vary, but most contain 16, 18, or 20 carbon atoms. (wikipedia.org)
- The simplest triglycerides are those where the three fatty acids are identical. (wikipedia.org)
- Fatty acids, monoglycerides (one glycerol, one fatty acid), and some diglycerides are absorbed by the duodenum, once the triglycerides have been broken down. (wikipedia.org)
- In the intestine, following the secretion of lipases and bile, triglycerides are split into monoacylglycerol and free fatty acids in a process called lipolysis. (wikipedia.org)
- When the body requires fatty acids as an energy source, the hormone glucagon signals the breakdown of the triglycerides by hormone-sensitive lipase to release free fatty acids. (wikipedia.org)
- As the brain cannot utilize fatty acids as an energy source (unless converted to a ketone), the glycerol component of triglycerides can be converted into glucose, via gluconeogenesis by conversion into dihydroxyacetone phosphate and then into glyceraldehyde 3-phosphate, for brain fuel when it is broken down. (wikipedia.org)
- Special enzymes on the walls of blood vessels called lipoprotein lipases must break down triglycerides into free fatty acids and glycerol. (wikipedia.org)
- The triglyceride molecule is a form of the chemical glycerol (tri=three molecules of fatty acid + glyceride=glycerol) that contains three fatty acids . (rxlist.com)
- Triglyceride molecules are esters of glycerol (a trihydric alcohol) with a range of different long chain fatty acids . (nationalgallery.org.uk)
- A 'drying' oil has a high proportion of triglyceride molecules containing unsaturated fatty acids . (nationalgallery.org.uk)
- The physical and chemical properties of these fatty acids and triglycerides are discussed, including the link to their sources and current availability to meet fuel demands. (wiley.com)
- Fatty acids are small building blocks that create types of fat such as sterols and triglycerides. (fitday.com)
- Fatty acids, sterols and triglycerides all fall under the category of lipid. (fitday.com)
- A triglyceride is a lipid formed from three fatty acids attached to a glycerol molecule. (fitday.com)
- This specification covers two grades of burner fuel consisting of triglycerides and naturally occurring constituents of triglycerides including monoglycerides, diglycerides, and free fatty acids and distinguished by the pour point. (astm.org)
- These dietary changes such as avoiding sugars, refined carbohydrates, and alcohol, plus adding more omega-3 fatty acids to the diet may lower triglycerides more quickly. (emedicinehealth.com)
- Coldwater fish oils, such as those in salmon, are high in omega-3 fatty acids that help lower triglycerides,' says Dinwoodey. (everydayhealth.com)
- Some fatty acids comprising a given triglyceride have one or more double bonds between their carbon atoms. (jrank.org)
Alcohol18
- 6 Excess calories, alcohol, 7 carbohydrates and simple sugars 8 , 9 that you consume are transformed into triglycerides and kept in your fat cells or liver 10 so they can be utilized as energy in the future. (mercola.com)
- However, the lit does say that people who drink alcohol and eat a lot of carbs have higher triglycerides. (celiac.com)
- When you eat, the extra calories, sugar, and alcohol that your body doesn't need right away is converted into triglycerides and stored in fat cells. (healthline.com)
- Beer, liquor, and wine all contain sugar, so all types of alcohol may be a problem for those with high triglycerides. (medicinenet.com)
- In addition to increasing triglycerides, alcohol consumption is linked to an increased risk of head and neck cancer, esophageal cancer, breast cancer, liver cancer, and colorectal cancer. (medicinenet.com)
- Being overweight , not getting enough exercise, smoking and drinking too much alcohol can all increase your triglyceride level. (drugs.com)
- Alcohol has a significant additive effect on the postprandial triglyceride peak when it accompanies a meal containing fat, especially saturated fat. (hindawi.com)
- This paper will focus on triglycerides after the consumption of such mixed meals as well as on the observation that alcohol may induce a very severe form of HT, which may be of clinical relevance with an increased risk of pancreatitis [ 4 ]. (hindawi.com)
- 11 ] studied triglyceride turnover in white adipose tissue and showed that chronic alcohol consumption inhibits the antilipolytic action of insulin. (hindawi.com)
- However, there are some beneficial aspects of moderate alcohol consumption, defined as one alcoholic beverage per day (a glass of wine, a bottle of beer, or an ounce of hard liquor), that may balance this triglyceride rise. (rxlist.com)
- Alcohol can raise triglycerides. (pcna.net)
- If you have high triglycerides, you may be asked to limit or avoid alcohol completely. (pcna.net)
- The problem is, triglycerides cannot be lowered overnight, and are usually caused by multiple factors such as obesity, excessive alcohol consumption, or poorly-managed diabetes. (healthcastle.com)
- Excess calories from alcohol will also cause your liver to make more triglycerides, which in turn causes less fat to be removed from your blood stream. (chemocare.com)
- If you are overweight and are not active, you may have high triglycerides, especially if you eat a lot of carbohydrate or sugary foods or drink a lot of alcohol. (uwhealth.org)
- Too much alcohol can raise triglycerides, so while moderate use may be safe for some people, others may need to avoid alcohol. (aicr.org)
- Alcohol is full of empty calories that are particularly bad for high triglycerides,' warns Dinwoodey. (everydayhealth.com)
- A heart-healthy diet to lower triglycerides includes lowering sugar, lowering fat, and limiting alcohol. (everydayhealth.com)
Bloodstream8
- When your body needs energy, triglycerides are released into your bloodstream to provide fuel for your muscles to work. (medlineplus.gov)
- Lipoproteins move cholesterol and triglycerides throughout the bloodstream. (livescience.com)
- Triglycerides are a form of fat appearing in the bloodstream, according to Mayo Clinic. (reference.com)
- Triglycerides are a kind of fat in the bloodstream that are usually used to provide energy, but too many can cause health problems, including metabolic syndrome when paired with other factors. (reference.com)
- After eating, lipoic acid supplementation increased the rate of disappearance of triglycerides in the bloodstream. (innovations-report.com)
- When you eat, the fat in your food is digested, and triglycerides are released into your bloodstream. (chemocare.com)
- Triglycerides are another class of fat found in the bloodstream, and they make up the bulk of your child's fat tissue. (childrenshospital.org)
- Triglycerides are a type of fat that play a key role in metabolism: Calories from food that aren't used are stored in fat cells as triglycerides where they can be called upon when energy is needed and released into the bloodstream. (verywellhealth.com)
Liver10
- The main purpose of VLDL is to distribute the triglyceride produced by your liver . (webmd.com)
- Avoiding added sugars (sweet crystalline carbohydrates like glucose and sucrose) in foods is important to lowering triglycerides because excess sugar can be converted by the liver into triglycerides, but often these foods sneak into our diets without our knowing. (rxlist.com)
- This helps lower triglycerides and reduces the risk of coronary heart disease, fatty liver disease, and diabetes. (medicinenet.com)
- And supplements also reduced the genetic expression of enzymes in the liver that synthesize triglycerides. (innovations-report.com)
- Liver cells can synthesize and store triglycerides. (wikipedia.org)
- Your liver produces triglycerides. (chemocare.com)
- After the presentation, a member of the audience asked how liver fat content could decrease while fat in the blood (triglycerides) increased. (medscape.com)
- a question fatty liver with inflammation from high cholesterol and triglycerides (NASH)? (yahoo.com)
- This is believed to be mediated by an increase in the hormone cortisol during stress, which acts upon the liver to increase the production of triglycerides. (nutritionfacts.org)
- APOIIIRx uses Isis' antisense technology - which inhibits a cell's production of disease-causing proteins - to target apoC-III, a gene produced in the liver that plays a central role in the regulation of serum triglycerides. (pharmatimes.com)
Treatment for high triglycerides3
- For most people, lifestyle changes are the main treatment for high triglycerides, according to the American Heart Association. (drugs.com)
- This is far less evidence than usually required for drug approval, and also substantially less than the body of evidence supporting standard fish oil as a treatment for high triglycerides. (stdavids.com)
- What Is the Treatment for High Triglycerides? (emedicinehealth.com)
Diet17
- Triglycerides generally respond quickly to changes in lifestyle and diet. (reference.com)
- As part of a balanced diet emphasizing soluble fiber and reduced processed sugar consumption, Cheerios can help reduce bad cholesterol and triglyceride lev. (reference.com)
- According to the latest dietary information the follow are the requirments for a triglyceride friendly diet. (lulu.com)
- Fruit is part of a healthy diet, but too much fruit may hinder your ability to lower your triglycerides. (medicinenet.com)
- You may be able to lower your triglycerides with a combination of losing weight, diet, and exercise. (fpnotebook.com)
- Effects of diet on muscle triglyceride and endurance performance. (springer.com)
- The good news is, diet and healthy eating habits can aid lowering triglycerides. (healthcastle.com)
- Any extra calories in your diet can be changed into triglycerides. (chemocare.com)
- People with extreme elevations in blood triglycerides, which is relatively uncommon, may need a very low-fat diet. (aicr.org)
- my triglyceride is at 1100mg, my doctor subscribed tricor, I don't want to take it, can I lower my level with diet and excercise? (thebody.com)
- Diet can have an important effect on triglycerides. (thebody.com)
- An improved diet, exercise, and prescription medications are among the steps you can take to lower high triglycerides. (verywellhealth.com)
- For example, lifestyle choices (like diet) paired with medications (such as beta-blockers) can complicate a person's genetic predisposition for high triglycerides. (verywellhealth.com)
- A healthy diet to lower triglycerides is an important part of getting your triglycerides under control. (everydayhealth.com)
- As a matter of fact, according to the American Heart Association, healthy choices in diet and exercise are even more important than medication to lower triglycerides for most people. (everydayhealth.com)
- A diet to lower triglycerides is about striving not to take in more calories than your body can use. (everydayhealth.com)
- However, if you have a very high triglycerides or a combination of high triglycerides and low HDL (good) cholesterol or high LDL (bad) cholesterol, you may need medication along with diet to lower triglycerides. (everydayhealth.com)
Reduce triglycerides2
- Because extra calories are converted to triglycerides and stored as fat, if you reduce your calories, you will reduce triglycerides. (healthline.com)
- It's impossible to put a number to just how much exercise you need to reduce triglycerides, but a smart approach is to aim for some kind of moderately intense exercise for at least 2.5 hours each week, says the American Heart Association. (healthcentral.com)
Coronary heart d2
- Cullen, P. "Evidence that Triglycerides are an Independent Coronary Heart Disease Risk Factor. (jrank.org)
- Are you sure you want to remove Triglyceride, high density lipoprotein, and coronary heart disease from your list? (openlibrary.org)
Calories15
- If you eat more calories than you need, the extra calories are changed into triglycerides. (medlineplus.gov)
- When you eat more calories than you need, the body stores those calories in the form of triglycerides, which can be used later by the body for energy," said Dr. Lauri Wright, a registered dietitian, member of the Academy of Nutrition and Dietetics , and an assistant professor of nutrition at the University of South Florida. (livescience.com)
- This is because sugars are often unneeded calories that are converted to triglycerides (a form of fat) for storage in the body. (wikihow.com)
- The body changes any calories it doesn't need immediately into triglycerides, which go into the fat cells for storage. (reference.com)
- Triglycerides can start to inch up whenever you eat more calories than you burn. (rxlist.com)
- Extra calories are turned into triglycerides and stored in fat cells for later use. (medlineplus.gov)
- If you eat more calories than your body needs, your triglyceride level may be high. (medlineplus.gov)
- Regularly consuming more calories than the body can burn off will result in an excessive number of triglycerides in the body. (medicalnewstoday.com)
- There's evidence that your triglycerides can go up if you get more than 60 percent of your daily calories from carbohydrates. (drugs.com)
- All excess calories are stored in the body as triglycerides. (livestrong.com)
- When consuming more calories than burned on a regular basis, this leads to an excess of triglycerides. (livestrong.com)
- Weight gain- People who are extremely overweight (obese), will have more calories converted into cholesterol and triglycerides. (chemocare.com)
- The body stores calories that it doesn't use right away as triglycerides. (healthline.com)
- Triglycerides are a type of fat found in the blood, created by the body after eating to store calories it does not need to use right away. (nutritionfacts.org)
- When you take in more calories than you need, your body changes those calories into triglycerides and they get stored in your fat cells. (everydayhealth.com)
Lipid panel4
- Often, triglycerides are measured as part of a lipoprotein panel ( lipid panel) in which triglycerides, cholesterol, HDL (high-density lipoprotein), and LDL (low-density lipoprotein) are measured at the same time. (rxlist.com)
- The machine collects a very small sample of blood from a finger stick and analyzes your triglycerides as part of a lipid panel. (healthline.com)
- In addition to triglycerides, the lipid panel will measure the major forms of cholesterol- total cholesterol , high-density lipoprotein cholesterol (HDL) , and low-density lipoprotein cholesterol (LDL) . (verywellhealth.com)
- High blood triglycerides are diagnosed with a routine blood test called a lipid panel. (emedicinehealth.com)
Borderline2
- About 25% of adults in the U.S. have a triglyceride level above 150 mg/dL, which is considered borderline high. (scienceblog.com)
- Borderline triglycerides are between 150 and 199 mg/dL. (everydayhealth.com)
Circulate in the b4
- Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. (labtestsonline.org)
- Triglycerides (TG), the main form of dietary fat, continuously circulate in the blood, but if their concentration elevates the risk of atherosclerosis and subsequently heart disease increases. (innovations-report.com)
- These triglycerides circulate in the blood to provide energy for your muscles to work. (healthline.com)
- Triglycerides are fatty molecules that circulate in the blood as a natural result of the breakdown of food in the gut. (ucdavis.edu)
Atherosclerosis5
- A high triglyceride level may lead to atherosclerosis , which increases your risk for heart attack and stroke. (medlineplus.gov)
- High triglycerides are a risk factor for atherosclerosis and cardiovascular disease. (redorbit.com)
- The potential is good that this could become another way to lower blood triglycerides and help reduce the risk of atherosclerosis. (innovations-report.com)
- Elevated triglycerides place an individual at risk for atherosclerosis. (rxlist.com)
- But like LDL cholesterol, excess triglycerides can lodge in arterial walls and increase the risk for atherosclerosis and other cardiac diseases. (ucdavis.edu)
Metabolic syndrome3
- But high triglycerides might raise your risk of heart disease and may be a sign of metabolic syndrome . (uwhealth.org)
- Metabolic syndrome is the combination of high blood pressure, high blood sugar, too much fat around the waist, low HDL ("good") cholesterol, and high triglycerides. (uwhealth.org)
- High triglycerides are a part of metabolic syndrome , a group of medical problems that increase your risk of heart attack, stroke, and diabetes. (uwhealth.org)
Level37
- Having a high triglyceride level along with a high LDL cholesterol may increase your chances of having heart disease more than having only a high LDL cholesterol level. (webmd.com)
- I hate to ask this question at the risk of sounding whiny over something that most people struggle at the opposite end of the spectrum, but I can't find anything saying whether an extremely low triglyceride level indicates a poor/unhealthy fat absorption. (celiac.com)
- So is it better to view a low triglyceride level as more than just a fat intake issue? (celiac.com)
- After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. (labtestsonline.org)
- The triglyceride level is a blood test to measure the amount of triglycerides in your blood. (medlineplus.gov)
- A very high triglyceride level may also cause swelling of your pancreas (called pancreatitis). (medlineplus.gov)
- To the authors' knowledge, this is both the highest triglyceride level recorded and the first report of a high triglyceride level as the apparent cause of a factitiously low glucose level. (nih.gov)
- If the level of triglycerides in your blood is elevated, it could mean you're at high risk for health problems. (healthline.com)
- If you typically consume more high-carbohydrate foods than you burn, you could have a high triglyceride level. (healthline.com)
- Median level of nonfasting triglycerides at baseline was 1.3 mmol/L in women and 1.7 mmol/L in men. (medpagetoday.com)
- For men, the hazard ratio at that level of triglycerides also was 1.2 (95% CI 0.8 to 1.7). (medpagetoday.com)
- The ideal level of triglycerides is 150 and below. (home-remedies-for-you.com)
- Example: Triglyceride level 270mg/dl = too high Discuss results with your health care professional. (livestrong.com)
- There is no set level at which triglycerides suddenly become dangerous. (livestrong.com)
- In a meta-analysis of 17 population-based prospective studies of 46,413 men and 10,864 women, adjusting for HDL cholesterol and other risk factors, there were increases of 16 and 42% in CVD end points in men and in women, respectively, for every 100-mg/dl increase in triglyceride level ( 2 ). (diabetesjournals.org)
- The National Cholesterol Education Program Adult Treatment Panel III (ATP III) recommended use of non-HDL cholesterol as a target of therapy if the triglyceride level exceeded 200 mg/dl. (diabetesjournals.org)
- Extremely high triglyceride level s (greater than 500mg/dl) may cause pancreatitis ( inflammation of the pancreas ). (rxlist.com)
- There was a guy who posted on this site that at one point he had a Triglyceride level of 4000, yes 4000. (healthboards.com)
- Therefore it is more common to see high triglyceride blood level in overweight or obese individuals. (healthcastle.com)
- High triglyceride level is associated with increased risk of heart disease. (healthcastle.com)
- Why is it bad to have high triglyceride level? (healthcastle.com)
- What is the triglyceride level test? (healthline.com)
- The triglyceride level test helps measure the amount of triglycerides in your blood. (healthline.com)
- VLDL measurements can be helpful information to have if you and your doctor are talking about ways to lower your triglyceride level. (healthline.com)
- Why do I need the triglyceride level test? (healthline.com)
- If you're receiving treatment for a high triglyceride level, your doctor will order this test more frequently to monitor the effectiveness of your treatment. (healthline.com)
- How is the triglyceride level test performed? (healthline.com)
- What are the risks associated with the triglyceride level test? (healthline.com)
- Triglycerides can be saturated (contain double bonds on a chemical level) and unsaturated (do not contain double bonds), meaning either solid at room temperature or liquid at room temperature due to their unique chemical structure. (fitday.com)
- Lifestyle modification is the best way to lower your bad cholesterol, increase your good cholesterol, and lower your triglyceride level," says Dinwoodey. (everydayhealth.com)
- A high triglyceride level combined with high LDL (bad) cholesterol or low HDL (good) cholesterol is linked with fatty buildups within the artery walls, which increases the risk of heart attack and stroke. (heart.org)
- Knowing your triglyceride level is as important as knowing your good and bad cholesterol numbers ,' says Danya L. Dinwoodey, MD, a cardiologist at the Lahey Clinic in Burlington, Mass. "In many cases, high triglycerides and low 'good' cholesterol numbers go together, and these risks may run in families. (everydayhealth.com)
- What should triglycerides level be? (davita.com)
- The most desirable level of triglycerides should be less than 150 mg/dL. (davita.com)
- How can people on dialysis manage their triglyceride level? (davita.com)
- When you weigh too much and sit too much you windup with Triglycerides overload, that doubles your risk for stroke and makes you six times more likely to have a heart attack, ideally your Triglyceride level should be under 100. (sharecare.com)
- Log an extra 5000 steps a day to slash your triglycerides level 19% in just 6 weeks. (sharecare.com)
Less than 1501
- Normal triglycerides are less than 150 mg/dL. (everydayhealth.com)
Blood39
- A triglycerides test measures the amount of triglycerides in your blood. (medlineplus.gov)
- A triglycerides test is a blood test. (medlineplus.gov)
- Triglycerides are usually measured in milligrams (mg) of triglycerides per deciliter (dL) of blood. (medlineplus.gov)
- Triglycerides are a type of fat found in the blood. (livescience.com)
- According to the Cleveland Clinic , cholesterol and triglycerides in their pure forms cannot mix with blood. (livescience.com)
- Cholesterol and triglyceride tests are blood tests that measure the total amount of fatty substances ( cholesterol and triglycerides ) in the blood . (webmd.com)
- Your yearly blood tests probably reflects an increase in triglycerides. (rxlist.com)
- Doctors use the following triglycerides ranges found in the blood to make determinations about your overall health risks. (rxlist.com)
- Triglycerides move via the blood from the gut to adipose tissue for storage. (labtestsonline.org)
- Most triglycerides are carried in the blood by lipoproteins called very low-density lipoproteins (VLDL) . (labtestsonline.org)
- National Cholesterol Education Program: "Step Nine: Treat Elevated Triglycerides," "Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). (webmd.com)
- The results shown in this table are based on a fasting state and are measured as milligrams of triglycerides per deciliter of blood (mg/dl). (healthline.com)
- The reasons doctors start to worry when triglycerides, which are a type of blood fat, inch their way up: The extra fat can begin to deposit along artery walls, contributing to an increased risk profile for heart disease and stroke (along with abnormal HDL, LDL, and diabetes which often occur in people with high TGs. (healthcentral.com)
- Quick aside: Triglycerides and cholesterol are both types of blood fat, but they're not the same. (healthcentral.com)
- LPL is required for normal metabolism of triglycerides in blood," Fong said. (redorbit.com)
- Testing for triglycerides is done with a fasting blood test. (livestrong.com)
- A blood test measures your triglycerides along with your cholesterol . (fpnotebook.com)
- If you have risk factors for heart disease, such as high blood pressure, smoking or diabetes, your doctor may recommend that you maintain lower than normal LDL cholesterol and triglycerides. (thebody.com)
- Conventionally, blood triglycerides are measured after an eight to twelve hour fast. (thedoctorwillseeyounow.com)
- High triglycerides contribute to hardening of blood vessels, which increases the risk of heart attack and stroke. (healthcastle.com)
- Triglycerides are fatty substances in your blood and body that get their name from their chemical structure. (chemocare.com)
- To test for hyperlipidemia, physicians rely on blood tests called lipid profiles that measure triglycerides as well as two types of the lipid cholesterol: low-density lipoprotein (LDL) or "bad" cholesterol, and high-density lipoprotein (HDL) or good cholesterol. (stdavids.com)
- Extra triglycerides enter your blood after you eat. (healthline.com)
- Very low-density lipoproteins (VLDLs) carry triglycerides through your blood. (healthline.com)
- Another way to monitor your triglycerides at home is to mail a sample of blood to a laboratory using a prepared kit. (healthline.com)
- Triglycerides are the least understood of the blood lipid components. (bellaonline.com)
- To learn more about triglycerides and how they work with your blood system, follow the links at the bottom of this article. (bellaonline.com)
- A blood test that measures your cholesterol also measures your triglycerides. (uwhealth.org)
- Q: Does someone with high blood triglycerides need to eat less fat? (aicr.org)
- Triglycerides are fat, but excess triglycerides in the blood usually come from over-production within the body, not from food itself. (aicr.org)
- Experts now say that high blood triglycerides are a sign of heart disease risk and also of an environment within the body likely to promote risk of diabetes and even some cancers. (aicr.org)
- Moderate walking 30 to 60 minutes a day can substantially lower blood triglycerides for many people through its effects on body hormones. (aicr.org)
- Genetic disorders, as well as certain diseases and drugs, can also cause high blood triglycerides. (aicr.org)
- The task force pointed out that the causes of excess triglycerides in the blood are not fully understood, but that many aspects of diagnosis and treatment are well established. (ucdavis.edu)
- Triglycerides are particles in the blood that transport fat. (medicinenet.com)
- Triglycerides are a type of fat-like substance in the blood that the body uses for energy. (emedicinehealth.com)
- Although the exact mechanisms are not fully known, elevated triglycerides allow increased blood clot formation and may slow the natural deterioration of clots once formed. (jrank.org)
- A blood test can be done to measure your triglycerides. (davita.com)
- His cholesterol was 132 in July 2013 / 173 Aug 2014 and triglycerides 107 in July 2013 / 250 Aug 2014 both are numbers from fasting blood tests. (drugs.com)
Obesity4
- Hence understanding the regulatory mechanisms underlying the storage and mobilization of triglycerides is essential to understanding the pathophysiology of obesity, diabetes, and related metabolic disorders. (diabetesjournals.org)
- The most common causes of high triglycerides are obesity and poorly controlled diabetes. (uwhealth.org)
- Elevated triglycerides are relatively common among people in the United States, and the prevalence is increasing due to growing rates of obesity and diabetes. (scienceblog.com)
- Activation of BAT might be a therapeutic approach to reduce elevated triglyceride concentrations and combat obesity in humans. (nih.gov)
Lipoproteins1
- High triglycerides are associated with increased risk for coronary artery disease (CAD) inpatients with other risk factors, such as low high-density lipoproteins (HDL)-cholesterol, some patient groups with elevated apolipoprotein B, and patients with forms of low-density lipoproteins (LDL) that maybe particularly atherogenic. (cdc.gov)
Excess4
- Triglycerides are necessary for health but in excess amounts, they may be harmful and may increase the risk of heart disease. (livescience.com)
- Your body turns excess carbohydrates that are not used for energy into triglycerides. (medicinenet.com)
- Excess fructose increases triglycerides. (medicinenet.com)
- But sometimes, too much carbohydrate (especially as sweets, soft drinks, large portions of juice and refined grains) is what's behind excess weight and over-production of triglycerides. (aicr.org)
Stroke12
- High triglycerides may put you at greater risk for a heart attack or stroke . (medlineplus.gov)
- Elevated triglycerides are worrisome because they can lead to an increased risk of heart disease and stroke. (wikihow.com)
- Just like cholesterol, high triglycerides can clot arteries, which can lead to heart attacks and stroke. (rxlist.com)
- Current stroke prevention guidelines provide advice on target cholesterol, but not nonfasting triglycerides. (medpagetoday.com)
- To explore a possible association between nonfasting triglycerides and ischemic stroke, the researchers analyzed data from the Copenhagen City Heart Study, which included 7,579 women and 6,372 men who had measurements of cholesterol and triglycerides at baseline between 1976 and 1978. (medpagetoday.com)
- In both men and women, those who averaged a higher overall triglyceride profile had a much higher risk of stroke. (livestrong.com)
- Triglycerides are a type of fat, and ischemic stroke is the most common type of stroke. (thedoctorwillseeyounow.com)
- Smoking can raise your triglycerides, lower "good" cholesterol, and is a major risk factor for heart attack and stroke. (pcna.net)
- In a recent large, randomized placebo-controlled study called REDUCE-IT, researchers found that the EPA-only medication combined with statin medication resulted in a 25% reduction in major cardiovascular events (heart attack, stroke and cardiovascular death) among people with high triglycerides. (scienceblog.com)
- Some triglycerides are needed but too much of them can put people at higher risk for heart attack , stroke , inflammation of the pancreas , and other health problems. (emedicinehealth.com)
- Research suggests that high triglycerides may increase the risk of heart attack and stroke. (everydayhealth.com)
- In this Health Smarts video, Dr. Oz explains why you should watch your triglycerides to lower your heart attack and stroke risk. (sharecare.com)
Glycerol5
- The second reaction is driven by the reagents from bottle 1, with lipase added in reagent 2 to convert triglycerides to glycerol, and 4-aminophenzone added to react with the hydrogen peroxide produced in the last reaction. (cdc.gov)
- Triglycerides are fatty acid esters of glycerol that have three hydroxyl groups. (cdc.gov)
- Triglycerides are measured enzymatically in serum using a series of coupled reactions in which triglycerides are hydrolyzed to produce glycerol. (cdc.gov)
- Triglycerides are tri-esters consisting of a glycerol bound to three fatty acid molecules. (wikipedia.org)
- Cocoa butter is unusual in that it is composed of only a few triglycerides, derived from palmitic, oleic, and stearic acids in the 1-, 2-, and 3-positions of glycerol, respectively. (wikipedia.org)
Cardiovascular disease3
- Anthony Gotto (New York, NY) gave an overview of the "evolving story" of HDL and triglycerides in cardiovascular disease (CVD) prevention. (diabetesjournals.org)
- Elevated plasma triglyceride concentrations and prolonged circulation of cholesterol-rich remnants, especially in diabetic dyslipidemia, are risk factors for cardiovascular disease. (nih.gov)
- Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. (medscape.com)
Diabetes1
- CONCLUSIONS In this cohort of participants with mild to moderate diabetic neuropathy, elevated triglycerides correlated with MFD loss independent of disease duration, age, diabetes control, or other variables. (diabetesjournals.org)
Pancreatitis2
- Very high triglycerides can result in pancreatitis. (cdc.gov)
- Very high triglycerides (over 500 mg/dl) can lead to pancreatitis, which is inflammation of the pancreas. (harvard.edu)
Heart disease10
- Triglycerides have been strongly linked to the occurrence of coronary artery disease or heart disease, as well as the occurrence of strokes and peripheral vascular disease. (livestrong.com)
- High triglycerides may increase your risk for heart disease. (pcna.net)
- A 2011 study found that feeding healthy study volunteers high fructose corn syrup increased their triglycerides and heart disease risk in just 2 weeks! (healthcastle.com)
- People with high triglycerides tend to have a much higher rate of heart disease and heart attack. (bellaonline.com)
- Triglycerides, a type of fat the body uses for energy, can increase the risk of heart disease. (news-medical.net)
- In fact, high triglycerides are as dangerous as bad cholesterol when it comes to your risk for heart disease . (everydayhealth.com)
- Unlike triglycerides, not all cholesterol contributes to heart disease. (everydayhealth.com)
- Some studies have shown a link between triglycerides and heart disease but other data in adults is less clear. (childrenshospital.org)
- High triglycerides can have just as much of an impact on your heart as other heart disease risks , such as high cholesterol . (everydayhealth.com)
- Do Triglycerides Provide Meaningful Information about Heart Disease Risk? (jrank.org)
20171
- WEDNESDAY, Oct. 25, 2017 -- Cholesterol might get all the attention on test results, but triglycerides are also part of the picture of good health. (drugs.com)
Raise triglycerides1
- Certain medicines may also raise triglycerides. (uwhealth.org)
Serum triglycerides2
- Serum triglycerides are generally increased maximally 3-6hrs after a meal particularly in diabetics. (thefreedictionary.com)
- Serum triglycerides are fatty compounds. (articlealley.com)
Body26
- Triglycerides are a type of fat in your body. (medlineplus.gov)
- Triglycerides are a type of fat the body uses to store energy and give energy to muscles. (webmd.com)
- Whether you eat triglycerides or your body makes them, the energy is either used or stored. (rxlist.com)
- When your body can't use all the triglycerides it consumes or produces, triglycerides are stored as fat cells. (rxlist.com)
- The good news is that there are many ways to start lowering your triglycerides and bringing your body back to good health. (rxlist.com)
- [1] Triglycerides are a form of fat that you get from food and are used by your body to store energy. (wikihow.com)
- [2] While it may be tricky to control the cholesterol your body makes, you can control the cholesterol and triglycerides you get from food. (wikihow.com)
- Triglycerides are a form of fat and a major source of energy for the body. (labtestsonline.org)
- In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. (labtestsonline.org)
- Your body makes some triglycerides. (medlineplus.gov)
- Insulin is a hormone your body produces to help you turn sugar from food into en. (articlealley.com)
- Triglycerides are the most common type of fat in the body. (medicalnewstoday.com)
- Triglycerides are the most common form of fat in the body. (healthline.com)
- So yeah: Having high triglycerides isn't great for your body. (healthcentral.com)
- The only way triglycerides can leave the body is by burning up the energy contained within them. (livestrong.com)
- It is necessary for the body to have some stores of triglycerides, giving the body enough energy to function even while asleep. (livestrong.com)
- Triglycerides are the main constituents of body fat in humans and other vertebrates, as well as vegetable fat. (wikipedia.org)
- Triglycerides are chemical compounds digested by the body to provide it with the energy for metabolism . (rxlist.com)
- HIV medications, as well as HIV itself, can also hurt your ability to process two key types of chemicals inside your body: cholesterol and triglycerides. (thebody.com)
- Losing 5-10 percent of your body weight may lower your triglycerides by 20 percent. (pcna.net)
- As with nearly all substances in our body, too much of anything causes health problems and this holds true with triglycerides as well. (home-remedies-for-you.com)
- Triglyceride is another form of fat that is most common in the human body and is transported to your. (home-remedies-for-you.com)
- In the most basic of terms, triglycerides are nothing but the fat contained within the body. (home-remedies-for-you.com)
- Triglycerides are how the body stores energy. (fitday.com)
- Triglycerides are a form of energy storage for the body and can be broken down easily for fuel. (fitday.com)
- Your body also makes triglycerides from the carbohydrates you eat and may send triglycerides to fat cells where they are stored for energy. (everydayhealth.com)
High triglycerides and low1
- Studies find it hard to separate out people who have high triglycerides and low LDL, so it could be that the two simply go together. (bellaonline.com)
Ways to lower triglycerides1
- What are some ways to lower triglycerides? (reference.com)
Causes of high triglycerides1
- Other causes of high triglycerides include hypothyroidism , kidney disease, and certain inherited lipid disorders . (uwhealth.org)
Healthy8
- Healthy adults should get a lipid profile, which includes a triglycerides test, every four to six years. (medlineplus.gov)
- University of Massachusetts Medical School: "Healthy Heart: What You Can Do to Lower Your Triglycerides. (webmd.com)
- If healthy lifestyle changes aren't enough to control high triglycerides, your doctor might recommend prescription medications, including statins , such as rosuvastatin calcium (Crestor) and atorvastatin calcium (Lipitor) or fibrates, such as gemfibrozil (Lopid) and fenofibrate (TriCor, Fenoglide). (healthline.com)
- Getting your triglycerides back into a healthy range often requires a one-two punch: healthier habits plus medication. (healthcentral.com)
- In a healthy individual, triglycerides should be under 150 mg/dl. (livestrong.com)
- Healthy food choices can help lower your triglycerides. (pcna.net)
- According to the American Heart Association, healthy lifestyle changes to counter those bad habits are the most important steps you can make to control high triglycerides, even more important than medication. (everydayhealth.com)
- Make a heart-healthy choice by trimming triglycerides. (davita.com)
Risk7
- These diseases have other risk factors, such as high cholesterol, so the role of triglycerides is still being determined. (livescience.com)
- Several case studies have shown that triglycerides could be an independent disease risk factor, however. (livescience.com)
- Omega-3 fatty acid supplementation derived from fish oil has earned a place in the management of lipid disorders and is now approved for decreasing risk in patients who have elevated triglycerides. (newsmax.com)
- I recommend that your cholesterol (HDL and LDL) and triglycerides be monitored for changes when fish oil is added as a supplement for cardiac and vascular disease risk reduction. (newsmax.com)
- The investigators suggested that a likely reason for the risk associated with nonfasting triglycerides is that they "are a marker of elevated lipoprotein remnant cholesterol. (medpagetoday.com)
- He noted that statins only reduce clinical events by approximately one-third (although subsequent speakers suggested that with more aggressive LDL targets events may be reduced by half), and recommended targeting HDL and triglyceride in addition to LDL cholesterol to achieve greater degrees of risk reduction. (diabetesjournals.org)
- Triglyceride was a risk factor for CVD among UKPDS participants after adjustment for age and sex but was not a significant factor when the other variables were included. (diabetesjournals.org)
Carbohydrates3
- If your doctor suspects that this might be an issue for you, reducing your carbohydrates can have a quick impact on your triglycerides. (wikihow.com)
- Complex carbohydrates offer more fiber, which can increase your HDL while lowering LDL and triglycerides. (wikihow.com)
- In cases in which dietary intake of sugar and white flour products is substantial, restricting simple carbohydrates and increasing dietary fiber are important adjuncts that can lower triglycerides substantially. (medscape.com)
Help lower your triglycerides1
- You also may need medicine to help lower your triglycerides. (uwhealth.org)
Amount of triglycerides1
- Getting the right amount of triglycerides is important to your sustained health. (rxlist.com)
Helps lower triglycerides1
- It also helps lower triglycerides. (rxlist.com)