Praziquantel: An anthelmintic used in most schistosome and many cestode infestations.Anthelmintics: Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.Schistosomicides: Agents that act systemically to kill adult schistosomes.Parasite Egg Count: Determination of parasite eggs in feces.Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.Schistosoma haematobium: A species of trematode blood flukes of the family Schistosomatidae which occurs at different stages in development in veins of the pulmonary and hepatic system and finally the bladder lumen. This parasite causes urinary schistosomiasis.Schistosomiasis haematobia: A human disease caused by the infection of parasitic worms SCHISTOSOMA HAEMATOBIUM. It is endemic in AFRICA and parts of the MIDDLE EAST. Tissue damages most often occur in the URINARY TRACT, specifically the URINARY BLADDER.Schistosoma mansoni: A species of trematode blood flukes of the family Schistosomatidae. It is common in the Nile delta. The intermediate host is the planorbid snail. This parasite causes schistosomiasis mansoni and intestinal bilharziasis.Clonorchiasis: Infection of the biliary passages with CLONORCHIS SINENSIS, also called Opisthorchis sinensis. It may lead to inflammation of the biliary tract, proliferation of biliary epithelium, progressive portal fibrosis, and sometimes bile duct carcinoma. Extension to the liver may lead to fatty changes and cirrhosis. (From Dorland, 27th ed)Oxamniquine: An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martindale, The Extra Pharmacopoeia, 31st ed, p121)Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.Albendazole: A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)Trematode Infections: Infections caused by infestation with worms of the class Trematoda.Platyhelminths: A phylum of acoelomate, bilaterally symmetrical flatworms, without a definite anus. It includes three classes: Cestoda, Turbellaria, and Trematoda.Schistosomiasis japonica: Schistosomiasis caused by Schistosoma japonicum. It is endemic in the Far East and affects the bowel, liver, and spleen.Schistosoma japonicum: A species of trematode blood flukes belonging to the family Schistosomatidae whose distribution is confined to areas of the Far East. The intermediate host is a snail. It occurs in man and other mammals.Schistosoma: A genus of trematode flukes belonging to the family Schistosomatidae. There are over a dozen species. These parasites are found in man and other mammals. Snails are the intermediate hosts.Methoprene: Juvenile hormone analog and insect growth regulator used to control insects by disrupting metamorphosis. Has been effective in controlling mosquito larvae.Antiparasitic Agents: Drugs used to treat or prevent parasitic infections.Cestode Infections: Infections with true tapeworms of the helminth subclass CESTODA.Clonorchis sinensis: A species of trematode flukes of the family Opisthorchidae. Many authorities consider this genus belonging to Opisthorchis. It is common in China and other Asiatic countries. Snails and fish are the intermediate hosts.Anticestodal Agents: Agents used to treat tapeworm infestations in man or animals.Paragonimiasis: Infection with TREMATODA of the genus PARAGONIMUS.Diphyllobothrium: A genus of tapeworm containing several species which occurs in the intestine of fish, birds, and mammals including man. Infection in humans is usually by eating uncooked fish. The larval stage is known as SPARGANUM.Ivermectin: A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.Diphyllobothriasis: Infection with tapeworms of the genus Diphyllobothrium.Paragonimus: A genus of lung flukes of the family Troglotrematidae infecting humans and animals. This genus consists of several species one of which is PARAGONIMUS WESTERMANI, a common lung fluke in humans.Heterophyidae: A family of intestinal flukes of the class Trematoda which occurs in animals and man. Some of the genera are Heterophyes, Metagonimus, Cryptocotyle, Stellantchasmus, and Euryhelmis.Opisthorchiasis: Infection with flukes of the genus Opisthorchis.Antibodies, Helminth: Immunoglobulins produced in a response to HELMINTH ANTIGENS.Echinococcosis: An infection caused by the infestation of the larval form of tapeworms of the genus Echinococcus. The liver, lungs, and kidney are the most common areas of infestation.Cysticercosis: Infection with CYSTICERCUS, the larval form of the various tapeworms of the genus Taenia (usually T. solium in man). In humans they penetrate the intestinal wall and invade subcutaneous tissue, brain, eye, muscle, heart, liver, lung, and peritoneum. Brain involvement results in NEUROCYSTICERCOSIS.Cestoda: A subclass of segmented worms comprising the tapeworms.Antigens, Helminth: Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.Opisthorchis: A genus of trematode liver flukes of the family Opisthorchidae. It consists of the following species: O. felineus, O. noverca (Amphimerus noverca), and O. viverrini. The intermediate hosts are snails, fish, and AMPHIBIANS.Echinostomiasis: Infection by flukes of the genus Echinostoma.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Parasitic Diseases, Animal: Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.Trematoda: Class of parasitic flukes consisting of three subclasses, Monogenea, Aspidogastrea, and Digenea. The digenetic trematodes are the only ones found in man. They are endoparasites and require two hosts to complete their life cycle.Taenia: A genus of large tapeworms.Toxascariasis: Infections with nematodes of the genus TOXASCARIS.Zimbabwe: A republic in southern Africa, east of ZAMBIA and BOTSWANA and west of MOZAMBIQUE. Its capital is Harare. It was formerly called Rhodesia and Southern Rhodesia.Toxascaris: An ascarid nematode found primarily in the small intestine of the larger Felidae as well as dogs and cats. It differs from TOXOCARA in that the larvae do not migrate through the lungs. It does occasionally produce visceral larva migrans (LARVA MIGRANS, VISCERAL) in man, although more rarely than does Toxocara.LaosArtemisinins: A group of SESQUITERPENES and their analogs that contain a peroxide group (PEROXIDES) within an oxepin ring (OXEPINS).Taeniasis: Infection with tapeworms of the genus Taenia.Helminthiasis: Infestation with parasitic worms of the helminth class.Metastrongyloidea: A superfamily of nematodes of the order STRONGYLIDA. Characteristics include a fluid-filled outer layer of cuticle and a reduced mouth and bursa.Intestinal Diseases, Parasitic: Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.Echinococcus granulosus: A species of hydatid tapeworm (class CESTODA) in the family Taeniidae, whose adult form infects the DIGESTIVE TRACT of DOGS, other canines, and CATS. The larval form infects SHEEP; PIGS; HORSES; and may infect humans, where it migrates to various organs and forms permanent HYDATID CYSTS.Uganda: A republic in eastern Africa, south of SUDAN and west of KENYA. Its capital is Kampala.Hymenolepiasis: Infection with tapeworms of the genus Hymenolepis.Echinostoma: A genus of intestinal flukes of the family Echinostomatidae which consists of many species. They occur in man and other vertebrates. The intermediate hosts are frequently mollusks.Neuroschistosomiasis: SCHISTOSOMIASIS of the brain, spinal cord, or meninges caused by infections with trematodes of the genus SCHISTOSOMA (primarily SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; and SCHISTOSOMA HAEMATOBIUM in humans). S. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. S. mansoni and S. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (From Joynt, Clinical Neurology, 1998, Ch27, pp61-2)Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.Cote d'Ivoire: A republic in western Africa, south of MALI and BURKINA FASO, bordered by GHANA on the east. Its administrative capital is Abidjan and Yamoussoukro has been the official capital since 1983. The country was formerly called Ivory Coast.Taenia solium: Species of tapeworm in the genus TAENIA, that infects swine. It is acquired by humans through the ingestion of cured or undercooked pork.
Praziquantel; however, is often the preferred treatment. It is given by mouth and used as a single dose. Common side effects ... It is more expensive than praziquantel. Oxamniquine is used for treatment of schistosomiasis. According to one systematic ... 026: Chapter 2: Bayer & E. Merck: Discovery and development of praziquantel*: Competing drugs for schistosomiasis treatment". ... "International Strategies for Tropical Disease Treatments - Experiences with Praziquantel - EDM Research Series No. ...
Praziquantel treatment is ineffective. There are case reports of nitazoxanide being successfully used in human fasciolosis ... In addition antibody concentration quickly drops post treatment and no antibodies are present one year after treatment, which ... Praziquantel is not effective, and older drugs such as bithionol are moderately effective but also cause more side effects. ... "CDC - Fasciola - Treatment". www.cdc.gov. Retrieved 2015-07-17. Mas-Coma, S; Bargues MD; Esteban JG (1999). "Human fasciolosis ...
For children there are treatment 3 options. Praziquantel given once, 25mg/kg. Nitazoxanide given at a dose of 100 mg for 3 days ... For children there are treatment 2 options. Praziquantel is given once, 25mg/kg. Niclosamide given for one day at 1 gram ... Praziquantel given once, 25mg/kg. Nitazoxanide given at a dose of 500 mg for 3 days. Niclosamide given for one day at 2 grams ... Praziquantel given once, 25mg/kg. Niclosamide given for one day at 2 grams followed by six days at 1 gram. ...
This infection can be treated with praziquantel. It's been noted that another possible treatment is with fenbendazole. Alaria ...
Praziquantel is generally administered in an oral form in one or two doses from 40-60 mg/kg body weight. Combination treatment ... If both praziquantel and artemether can be used together, the entire lifespan of S. japonicum would be covered in the ... Praziquantel is most active against adult worms. However, it has been found that artemether prevents the development of adult ... The therapy of choice is praziquantel, a quinolone derivative. ...
Treatment. Main article: Deworming. Tapeworms are treated with medications taken by mouth, usually in a single dose. The ... drug of choice for tapeworm infections is praziquantel. Niclosamide can also be used. ... Symptoms vary widely, as do treatment options, and these issues are discussed in detail in the individual articles on each worm ...
Treatment. The prescription drug Praziquantel is usually prescribed in a single dose to patients suffering from infection ... Research has shown that the cysticercoid phase of H.nana's life cycle is the most susceptible to the Praziquantel treatment. ... "Praziquantel Treatment in Trematode and Cestode Infections: An Update". Infection & Chemotherapy. 45 (1): 32-43. doi:10.3947/ic ... This research fully indicated the paralyzing and deadly nature of Praziquantel on H. nana, H. diminuta, H. microstoma. ...
Treatments containing antimony, known as antimonials, are used as emetics. Antimony compounds are used as antiprotozoan drugs. ... It was subsequently replaced by praziquantel. Antimony and its compounds are used in several veterinary preparations, such as ... Antimony-based drugs, such as meglumine antimoniate, are also considered the drugs of choice for treatment of leishmaniasis in ...
Treatment with praziquantel proved to be effective again. None of the human cases of infection with either the North American ... This time, praziquantel was the effective treatment of choice. In 1990, the first case of human infection with N. salmincola ... 1989) Praziquantel for treatment of human Nanophyetus salmincola (Troglotrema salmincola) infection. 160(5):896-9. RE Milleman ... Praziquantel, 20 mg/kg body weight, three times a day. Praziquantel causes immobilized contraction of the worm, such that it ...
Praziquantel is the drug of choice for treatment. Treatment is effective in early or light infections. Heavy infections are ... Rabbani GH, Gilman RH, Kabir I, Mondel G (1985). "The treatment of Fasciolopsis buski infection in children: a comparison of ... Studies of the effectiveness of various drugs for treatment of children with F. buski have shown tetrachloroethylene as capable ... and treatment. 1. Sydenham society. pp. 433-7. Odhner TH (1902). "Fasciolopsis Buski (Lank.)[= Distomum crassum Cobb.], ein ...
Treatment recommendations for subcutaneous cysticercosis includes surgery, praziquantel and albendazole. Skin. In ... "Albendazole versus Praziquantel in the Treatment of Neurocysticercosis: A Meta-analysis of Comparative Trials". PLOS Neglected ... Praziquantel (PZQ) is the drug of choice. In neurocysticercosis praziquantel is widely used. Albendazole appears to be more ... Treatment of those with neurocysticercosis may be with the medications praziquantel or albendazole. These may be required ...
Other treatments that have seen positive results are Praziquantel and Albendazole. Praziquantel causes cell membranes of worms ... She received proper treatment and made a full recovery. In all of these recent cases, the infected individuals had been exposed ... The most common and widely recognized treatment for this disease is surgical removal of the cysts. However, this is not always ... The man was treated with praziquantel. The drug successfully killed the larvae and his infection never returned. The cyst ...
Control of opisthorchiasis relies predominantly on antihelminthic treatment with praziquantel. The single dose of praziquantel ... the short-term treatment of Opisthorchis viverrini-infected hamsters with praziquantel (400 mg per kg of live weight) induced a ... "Opisthorchiasis - Treatment Information". CDC - DPDx. 2013-11-29. Retrieved 2015-09-07. Soukhathammavong, P.; Odermatt, P.; ... Keiser, J.; Utzinger, J. R. (2007). "Artemisinins and synthetic trioxolanes in the treatment of helminth infections". Current ...
International Strategies for Tropical Disease Treatments: Experiences with Praziquantel (1998) • The Health Insurance ...
However, drugs like praziquantel can be administered to treat the infection. A study was conducted on free-range Florida ... In the study, the intensity of infection of S. mansonoides increased 6 months after treatment instead of decreasing. Lee SU, ... and the efficacy of the current anthelmintic treatment protocol." Journal of Wildlife Diseases. 2006 Apr;42(2):402-6. ... panthers on the effectiveness of anthelmintic treatment. ...
Treatment of opisthorchiasis is generally with a single dose of praziquantel. List of parasites (human) Blanchard, R. (1895). ... Patient outcome is dependent on early detection and treatment. Human cases of opisthorchiasis may affect the liver, pancreas, ...
Oxamniquine is listed for use when praziquantel treatment fails. *^ Only for the presumptive treatment of epidemic meningitis ... To be used for the treatment of Trypanosoma brucei gambiense infection *^ To be used for the treatment of the initial phase of ... To be used for the treatment of T. b. gambiense infection *^ Only to be used in combination with eflornithine, for the ... For the treatment of cytomegalovirus retinitis (CMVr). *^ For severe illness due to confirmed or suspected influenza virus ...
... in general praziquantel is considered the first option for treatment. The treatment objective is to cure the disease and to ... Other possible treatments include a combination of praziquantel with metrifonate, artesunate, or mefloquine. A Cochrane ... There are two drugs available, praziquantel and oxamniquine, for the treatment of schistosomiasis. They are considered ... Praziquantel is also the treatment recommended by the World Health Organization for those who are known to be infected. ...
Anti-parasitic medicines like Praziquantel and mebendazole. Some infectious diseases have no treatments that work well. For ...
Drugs commonly used for treatment of hymenolepiasis are praziquantel, niclosamide, and paromomycin. Vasyl Tkach (1 June 2010 ...
Albendazole may also be an effective drug for treatment, but literature backing its efficacy is lacking. Chang-Min CHO, Won- ... Echinostome infections can be successfully eradicated through the use of praziquantel (PZQ). It is recommended that patients ...
Oral anti-parasitic drugs such as praziquantel are the treatment of choice. Treatment with praziquantel has been approved by ... Usual treatments are with praziquantel (5-10 mg/kg, single-administration) or niclosamide (adults and children over 6 years: 2 ... "Signs, symptoms and treatment of taeniasis/cysticercosis". Retrieved 13 March 2014. Flisser, A.; Avila G; Maravilla P; ... dosages and treatment schemes, against Taenia saginata cysticercus in cattle experimentally infected". Experimental ...
The standard treatment is an anthelmintic such as Praziquantel, Triclabendazole, or Mirazid. Dicrocoeliasis is believed to be ... Treatment can be difficult due to the fluke's complex life-cycle. Various antihelminths, especially Netobimin, have been shown ... Because human infections with Dicrocoelium dendriticum are so rare, there are multiple suggestions for treatment. ... "A review of dicrocoeliosis of ruminants including recent advances in the diagnosis and treatment". Veterinary Parasitology. 107 ...
Praziquantel is an effective treatment for tapeworm infection, and is preferred over the older niclosamide. Cestodes can also ... Certain medicines are used to remove it, such as praziquantel or albendazole. Physicians also give enema treatment to the ... Symptoms vary widely, as do treatment options, and these issues are discussed in detail in the individual articles on each worm ... Scholar, Eric M.; Pratt, William B. (2000). "Treatment of Parasitic Infection". The Antimicrobial Drugs. Oxford University ...
Praziquantel is an effective treatment against all species of Schistosoma that infect humans. Administering treatment at the ... Oxaminiquine is another treatment for schistosomiasis, but it is not widely available, nor is it routinely used. Tchuem ...
Use in treatment of aspergillosis has been reported. It is also used in anti-fungal wallboards as a mixture with ... Upon treatment with base, this undergoes a nitrene insertion reaction (4) to produce tiabendazole (5). ... it is also used as a prophylactic treatment for Dutch elm disease. ... "Efficacy and safety of ivermectin and thiabendazole in the treatment of strongyloidiasis". Expert Opin Pharmacother. 5 (12): ...
Efficacy of oxamniquine and praziquantel in treatment of Schistosoma mansoni infection: a controlled trial. ... Oxamniquine or praziquantel cause death of the adult worm decreasing the inflammatory response being used in non CNS S.. ... Alternatives to praziquantel include oxamniquine for S.. This is an ancient disease that may have had historical consequences ... A drug used in the treatment of SCHISTOSOMIASIS. It is on the WHO official list.. ...
Purchase Praziquantel Best Price Praziquantel. a7ek. The successful treatment would seem to be the radical operative correction ... Buy Praziquantel For Humans praziquantel mg praziquantel biltricide praziquantel buy praziquantel buy praziquantel online ... Praziquantel Price buy cheap praziquantel praziquantel price buy praziquantel online order praziquantel online Cleocin Costco ... praziquantel tablets praziquantel uk moxidectin praziquantel praziquantel price order praziquantel online purchase praziquantel ...
Treatment. Therapy for infection with D latum consists of either praziquantel or niclosamide (Box 2). Follow-up examinations of ... stool should be performed 1 and 3 months after treatment.. Prognosis. Since the disease is not commonly associated with severe ...
Your vet might prescribe praziquantel, marketed under the trade name Droncit and Drontal, to eradicate the worms. Praziquantel ... Diagnosis and Treatment. Your veterinarian will request that you bring in a fecal sample so she can perform a fecal flotation ...
... and the two main ones used are ni-closamide and praziquantel, both of which are highly effective. A single dose of praziquantel ... The control cure of this infection is absence of eggs in the feces one month after treatment. ... A single dose of praziquantel 600 mg was given, and the patients feces were found to be egg-free after one month. ... A single dose of praziquantel (600 mg) was sufficient to cure the infection. ...
Additionally, antibacterial and antifungal agents that can also be used for treatment of protozoal infections, such as the 5- ... Most helminth infections in humans can be treated with one of five drugs, namely, albendazole, mebendazole, praziquantel, ... Additionally, antibacterial and antifungal agents that can also be used for treatment of protozoal infections, such as the 5- ... Additionally, antibacterial and antifungal agents that can also be used for treatment of protozoal infections, such as the 5- ...
Treatment is with bithionol. Preventive measures include adequate cooking of crustaceans used as food and protection of waters ... and their symptoms resolved after therapy with praziquantel. ... of two single-day regimens of triclabendazole for the treatment ...
Paragonimiasis cases were treated with praziquantel (3 x 25mg/kg/day for 3 days). ... motivation to participate will increase with the subsequent successful management of chronic cough patients and TB treatment. ■ ...
The journal welcomes articles describing research on pathogenesis, epidemiology of infection, diagnosis and treatment, ... Praziquantel Failure in the Treatment of Fasciola hepatica. David Michael Patrick and Judith Isaac-Renton ... David Michael Patrick and Judith Isaac-Renton, "Praziquantel Failure in the Treatment of Fasciola hepatica," Canadian Journal ...
... *Download PDF Copy ... No previous study has examined whether praziquantel treatment at 12-16 weeks gestation improves pregnancy outcomes or whether ... Despite World Health Organization recommendations to offer pregnant women treatment with praziquantel, many nations continue to ... Deferring treatment only exacerbates the morbidity of the patients.. Nearly 40 million women of reproductive age are infected ...
Initial treatment with bithionol failed. The patient was then treated with praziquantel 75 mg/kg body weight a day for 2 days ... A concurrent asymptomatic Clonorchis infection was also cured following praziquantel treatment. Side effects were minor. ... Successful Praziquantel Treatment of Paragonimiasis Following Bithionol Failure A Case Report* * Richard J. Johnson†, Steven B ... Initial treatment with bithionol failed. The patient was then treated with praziquantel 75 mg/kg body weight a day for 2 days ...
International Strategies for Tropical Disease Treatments - Experiences with Praziquantel - EDM Research Series No. 026. (1998; ... Chapter 6: Demand for praziquantel and national distribution*. * By Michael R. Reich and Ramesh Govindaraj, with assistance ... This chapter provides an assessment of the global demand for praziquantel, and describes national distribution of the drug in ... The chapter also discusses the impact of praziquantels high cost on the operation of schistosomiasis control programmes. The ...
Impact of praziquantel treatment on CD4+,CD4+/CD8+, HIV-1 viral loads haemoglobin level, reversibility of liver pathology and ... A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes. The recruitment ... Also, treatment of helminth infections using praziquantel and albendazole among HIV-1 infected individuals will lead to ... The study will also assess the impact of praziquantel treatment on S. mansoni related morbidities in co-infected HIV positive ...
The therapeutic potential of praziquantel for the treatment of S. mansoni infections was first explored by Andrews and Gönnert ... International Strategies for Tropical Disease Treatments - Experiences with Praziquantel - EDM Research Series No. 026. (1998; ... Discovery process and initial testing of praziquantel. At the beginning of the 1970s, the search for effective tranquilizers ... The tests found no mutagenic, carcinogenic, embryotoxic, or teratogenic activity of praziquantel (WHO, 1985). ...
B. L. Webster, O. T. Diaw, M. M. Seye et al., "Praziquantel treatment of school children from single and mixed infection foci ... N. B. Kabatereine, J. Kemijumbi, J. H. Ouma et al., "Efficacy and side effects of praziquantel treatment in a highly endemic ... The Efficacy of Single-Dose versus Double-Dose Praziquantel Treatments on Schistosoma mansoni Infections: Its Implication on ... B. Gryseels, L. Nkulikyinka, and M. H. Coosemans, "Field trials of praziquantel and oxamniquine for the treatment of ...
... as a potential partner for praziquantel in a combination treatment. Finally, we demonstrated that this praziquantel-omeprazole ... Praziquantel is the drug of choice for treatment of at-risk populations; however, evolution of resistant worms under repeated ... treatment is of great concern. Combining praziquantel with another drug could not only increase efficacy of praziquantel, but ... Our study reports the global praziquantel-induced transcriptional changes of Schistosoma mansoni adult worms in vitro, in the ...
In order to assess the efficacy and toxicity of praziquantel in the treatment of Schistosoma mekongi, 11 infected Laotian ... After 2.5 months the patients were re-evaluated and subjected to the opposite treatment, and final follow-up took place 5-7 ... All but one person was cured (91%). This patient failed to show a decrease in egg excretion 2.5 weeks after praziquantel ... Initially, one group of five received praziquantel 60 mg/kg body weight in three divided doses orally while the remainder ...
... treatment with mebendazole, emetine with mebendazole and praziquantel ... Mebendazole in the treatment of the acute and chronic stages of helminthiases. II. Mebendazole (Vermox) in the treatment of ... Mebendazole in treatment of the acute and chronic stage of helminthiasis part 1 mebendazole treatment of acute and chronic ... Mebendazole in the treatment of acute and chronic helminthiasis 2. mebendazole vermox in the treatment of alveococcosis and ...
... of repeated praziquantel chemotherapy on subclinical morbidity related to Schistosoma japonicum infection. We repeated stool ... were benefits of repeated treatments. Further research is needed to understand why some patients developed fibrosis despite ... Five-year impact of repeated praziquantel treatment on subclinical morbidity due to Schistosoma japonicum in China Li, Y.S. ; ... Five-year impact of repeated praziquantel treatment on subclinical morbidity due to Schistosoma japonicum in China ...
The use of height versus weight in determining praziquantel dose for treatment of Schistosomiasis in children * MO Swar ... Background: Praziquantel (PZQ) is currently the drug of choice in treatment of Schistosomiasis because of its high efficacy, ...
Despite treatment with praziquantel (PZQ) at 40 mg/kg in food, several chimpanzees on Ngamba Island Chimpanzee Sanctuary (NICS ... Praziquantel, Schistosoma mansoni, Schistosomiasis mansoni, Treatment Outcome, Uganda, Urine ... schistosome genetic diversity and praziquantel treatment. Parasitology, 140 (3). pp. 285-295. ... management plan is required which should combine active case-detection with an insistent treatment regime with praziquantel for ...
Praziquantel treatment during pregnancy boosted anti-worm IgG isotypes and to a lesser extent IgE, but these boosts were less ... At six weeks after praziquantel treatment during pregnancy S. mansoni infection was not detectable in 81.9% of the women and ... We have therefore evaluated the effects on infection intensity and the immunological effects of praziquantel treatment against ... Infection intensity after treatment was assessed by a single Kato-Katz examination of stool samples with duplicate slides and ...
Used for the Treatment of External and Internal Parasites Flukes Flatworms and Tapeworms Praziquantel is known to be one of the ... Praziquantel is known to be one of the safest most effective pond fish medications available for treating a vast array of ... One of the biggest advantages in large ponds is that water changes are not necessary and it only takes one treatment. ... Used for the Treatment of External and Internal Parasites, Flukes, Flatworms and Tapeworms ...
Professional guide for Praziquantel. Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse ... Treatment (CDC 2018c; Red Book [AAP 2018]): Note: Repeat treatment may be needed in 2 to 4 weeks to increase effectiveness ... Clinical experience suggests the utility of praziquantel in the treatment of a broad range of trematode and cestode infections ... Based on the IDSA/ASTMH guidelines for the diagnosis and treatment of neurocysticercosis, praziquantel, in combination with ...
Easy-to-read patient leaflet for Praziquantel. Includes indications, proper use, special instructions, precautions, and ... This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data ... What do I need to tell my doctor BEFORE I take Praziquantel?. *If you have an allergy to praziquantel or any other part of ... How is this medicine (Praziquantel) best taken?. Use praziquantel as ordered by your doctor. Read all information given to you ...
SchistosomaAlbendazoleInfectionsIvermectinInfectionControlled drugTreat schistosomiasisSide effects of praziquantelAnthelminticSingle-DoseWeeks after praziquantelToxicity of praziquantelMebendazole and praziquantelDose of praziquantelEffect of praziquantelAllergy to praziquantelChemotherapyParasitesDosesTapewormsDiagnosisSchistosomiasis during prAnthelminthicFlukesOxamniquineBiltricidePregnancyAntiparasiticDosagePlaceboEmodepsideParagonimiasisSchool-aged childrenAntigensFormulationHumansOutcomesVersusTherapeuticEchinococcosisInfectious DiseasesSevereMedicationsWormsSpeciesClinicalNeglected TropicalTrialsAdverseLiver fibrosisMorbidityEffective
- Epidemiology of Human Immunodeficiency Virus (HIV-1) and Schistosoma Mansoni Co-infections and Its Impact on Anthelminthic Treatment Outcome Among HIV-1 Infected Individuals in Fishing Communities in Mwanza Region, Northwestern Tanzania. (clinicaltrials.gov)
- In order to assess the efficacy and toxicity of praziquantel in the treatment of Schistosoma mekongi , 11 infected Laotian refugees, all belonging to a single extended family, were treated in a double-blind crossover trial with praziquantel and placebo. (ajtmh.org)
- The therapeutic potential of praziquantel for the treatment of S. mansoni infections was first explored by Andrews and Gönnert in 1977 at the Research Centre Wuppertal using the schistosoma/mouse model (Andrews et al. (who.int)
- Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger," Acta Tropica , vol. 128, no. 2, pp. 334-344, 2013. (hindawi.com)
- Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania," American Journal of Tropical Medicine and Hygiene , vol. 83, no. 4, pp. 951-957, 2010. (hindawi.com)
- We report the 5-year impact (1996-2001) of repeated praziquantel chemotherapy on subclinical morbidity related to Schistosoma japonicum infection. (rero.ch)
- Despite treatment with praziquantel (PZQ) at 40 mg/kg in food, several chimpanzees on Ngamba Island Chimpanzee Sanctuary (NICS) continue to excrete eggs of Schistosoma mansoni. (surrey.ac.uk)
- We have therefore evaluated the effects on infection intensity and the immunological effects of praziquantel treatment against Schistosoma mansoni during pregnancy, compared with treatment after delivery. (biomedcentral.com)
- 2007). In particular, we describe the results of a sub-study designed to examine the immunological effects of treating Schistosoma mansoni with praziquantel during pregnancy, compared with the effects of treatment after delivery. (biomedcentral.com)
- Praziquantel (PZQ) efficacy and immune responses to schistosome antigens following cure were investigated in Schistosoma mansoni infected adult fishermen resident in Kisumu, Kenya with or without human immunodeficiency virus (HIV) co-infection. (ac.ke)
- The efficacy of taking two doses of oral PZQ for the treatment of Schistosoma haematobium was examined among school children in Nigeria. (biomedcentral.com)
- Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ). (biomedcentral.com)
- Efficacy and side effects of praziquantel treatment against Schistosoma haematobium infection among primary school children in Zimbabwe. (ac.zw)
- We examined the efficacy of praziquantel against Schistosoma haematobium among primary school children during a school-based deworming programme in the Burma Valley commercial farming area and the Nyamaropa rural areas in Zimbabwe, where the disease is highly endemic. (ac.zw)
- An association study of a cohort of one hundred seventy seven Sudanese patients infected with Schistosoma mansoni (82 males 46%, 95 females 54%) was conducted to evaluate the factors controlling the regression of liver fibrosis 39 months after treatment with PZQ using ultrasound evaluation. (edu.sd)
- This study aims to determine the efficacy of repeated PZQ treatments against Schistosoma mansoni infection in school-aged children in Côte d'Ivoire using the traditional KK technique, as well as more sensitive antigen- and DNA-detection methods. (springer.com)
- This study aimed to evaluate the role of praziquantel (PZQ) and artemether (ART) as anti-angiogenic and anti-lymphangiogenic drugs in Schistosoma mansoni induced experimental hepatic model through immunohistochemical and serological studies, this can be used as a potential novel prophylactic approach in hepatic malignancy prevention and possible management. (degruyter.com)
- Based on above mentioned tools, we decided to assess the accuracy of CAA measurement to determine the Schistosoma infection in two specific conditions: A) as a diagnostic tool for S. haematobium to prepare for the future implementation of a PZQ test-and-treat strategy and B) as a diagnostic tool to measure efficacy of praziquantel in schistosomiasis and pregnancy intervention trials. (clinicaltrials.gov)
- Also, treatment of helminth infections using praziquantel and albendazole among HIV-1 infected individuals will lead to reduction in HIV-1 viral loads, improvement of CD4+ counts, CD4+/CD8+ ratio and Hb levels, improved weight gain and reduction of episodes of HIV-1 related opportunistic infections. (clinicaltrials.gov)
- Data from the phase II and phase III portions of a randomized, double blind, placebo-controlled study supports the use of praziquantel (in combination with albendazole) in the treatment of parenchymal neurocysticercosis [Garcia , [Garcia . (drugs.com)
- A randomised multicentre study to compare the safety and efficacy of albendazole and metronidazole in the treatment of giardiasis in children. (ijtmgh.com)
- Albendazole chemotherapy was found to be the primary pharmacological treatment to consider in the medical management of CE. (springer.com)
- Nevertheless, combined treatment with albendazole plus praziquantel resulted in higher scolicidal and anti-cyst activity and was more likely to result in cure or improvement relative to albendazole alone. (springer.com)
- Four treatment options are currently available: i) surgery, ii) PAIR, iii) chemotherapy with albendazole, mebendazole or other anthelmintic drugs, and iv) watch and wait for inactive or silent cysts. (springer.com)
- iii) Should albendazole be administered alone or in combination with praziquantel? (springer.com)
- Treatment is typically with albendazole or praziquantel, which kill the worm. (infoplease.com)
- 1983). The drug was first developed for veterinary use and later tested for the treatment of helminthic infections in humans. (who.int)
- Praziquantel is the drug of choice against all schistosome infections and has shown reliable therapeutic effectiveness. (biomedcentral.com)
- Clinical experience suggests the utility of praziquantel in the treatment of a broad range of trematode and cestode infections [Liu . (drugs.com)
- One hundred and twenty-one children were egg negative at four weeks post treatment, among which 1 (6.3) and 120 (52.4%) had heavy and light infections, respectively. (biomedcentral.com)
- See Guidelines for Overseas Presumptive Treatment of Strongyloidiasis, Schistosomiasis, and Soil-Transmitted Helminth Infections . (cdc.gov)
- PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats. (medi-vet.com)
- Randomised Open-label Trial Testing Presumptive Anthelminthic Treatment on Progression of HIV in ART-naïve HIV-positive Patients in a Rural African Setting With Presumed High Prevalence of Helminth Infections. (nih.gov)
- The purpose of this study was 2-fold 1) to investigate the prevalence of gastrointestinal parasite infection in cats reared in Daegu, Republic of Korea and 2) to assess the efficacy and safety of a topical emodepside/praziquantel formulation for cats with parasitic infections. (bvsalud.org)
- Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and growing concerns of PZQ resistance have revealed the limitations of this strategy. (springer.com)
- The drug of choice for tapeworm infections is praziquantel . (wikipedia.org)
- before treatment, is associated with higher efficacy of praziquantel in the treatment of S. mansoni infections. (biomedcentral.com)
- Fungicide treatments and water changes are essential for fungal infections. (reference.com)
- According to one systematic review, praziquantel is the standard treatment for S. mansoni infections and oxamniquine also appears effective. (wikipedia.org)
- For the single dose treatment of infections with cestodes (tapeworms) of the species Anoplocephala perfoliata sensitive to praziquantel. (viovet.co.uk)
- In horses with severe infections, treatment may result in mild, transient colic and loose faeces due to the destruction of the tapeworms. (viovet.co.uk)
- It was determined also that the Praziquantel was effective at killing and stopping Fluke (monogenetic trematode) infections. (koivet.com)
- Ivermectin is not administered to refugees who have resided or traveled in Loa loa -endemic countries due to risk of encephalopathy associated with ivermectin treatment in a person with Loa loa infection. (cdc.gov)
- Equimax contains ivermectin for routine worm control and praziquantel one of the world's most effective tapeworm treatments. (horsewormers.com)
- It contains three active ingredients, Ivermectin, Pyrantel and Praziquantel, all proven to prevent and kill various parasites. (petside.com)
- Ivermectin 1.87%/praziquantel 14.03% - Anthelmintic and Boticide. (smartpakequine.com)
- A concurrent asymptomatic Clonorchis infection was also cured following praziquantel treatment. (ajtmh.org)
- Praziquantel treatment of school children from single and mixed infection foci of intestinal and urogenital schistosomiasis along the Senegal River Basin: monitoring treatment success and re-infection patterns," Acta Tropica , vol. 128, no. 2, pp. 292-302, 2013. (hindawi.com)
- Reduction of prevalence and intensity of infection, and improvement of subclinical morbidity, were benefits of repeated treatments. (rero.ch)
- Infection intensity after treatment was assessed by a single Kato-Katz examination of stool samples with duplicate slides and categorised as undetected, light (1-99 eggs per gram (epg)), moderate (100-399 epg) or heavy (≥400 epg). (biomedcentral.com)
- At six weeks after praziquantel treatment during pregnancy S. mansoni infection was not detectable in 81.9% of the women and prevalence and intensity had decreased to 11.8% light, 4.7% moderate and 1.6% heavy a similar reduction when compared with those first treated after delivery (undetected (88.5%), light (10.6%), moderate (0.9%) and heavy (0%), p = 0.16). (biomedcentral.com)
- We investigated the effect of chronic S. japonicum infection, PZQ chemotherapy, and soluble egg antigen (SEA) treatment on whole-body metabolic homeostasis and hepatic insulin sensitivity in mouse models. (biomedcentral.com)
- This study indicated that chronic S. japonicum infection with PZQ chemotherapy and SEA treatment can regulate metabolic homeostasis and protect against metabolic syndrome by promoting Th2 and regulatory responses in the liver. (biomedcentral.com)
- Seventy-two individuals remained infected at 6 weeks post treatment, among which 3 and 69 individuals had heavy and light infection, respectively. (ac.zw)
- Our study demonstrates that praziquantel is efficacious against S. haematobium in Zimbabwe, although low levels of persistent infection warrant further investigation. (ac.zw)
- Ideally this would lead to a prolongation of the chronic phase of HIV infection and to a delay in the time when anti-retroviral treatment needs to be started. (nih.gov)
- The primary outcome of the study will be the difference in CR of intense versus standard treatment with PZQ on individuals with a confirmed S. mansoni infection measured by KK. (springer.com)
- Treatment for tapeworm infection should be aimed at both the active tapeworm load and controlling the intermediate host (usually fleas). (petplace.com)
- With treatment, the tapeworm infection goes away. (medlineplus.gov)
- Our study suggests that neither a S. mansoni infection nor praziquantel administration triggers a significant effect on the microbial composition and that a higher abundance of Fusobacterium spp. (biomedcentral.com)
- This medication is an anthelminthic and immunomodulator, prescribed for cancer treatment and also used for roundworm infection. (medindia.net)
- As tapeworm infection is unlikely to occur in horses before two months of age, treatment of foals below this age is not considered necessary. (viovet.co.uk)
- However, the treatment window should be reconsidered to reduce the risk of re-infection: a general rule is to treat as close as possible to entry into a non-infected country. (europa.eu)
- Most immunodiagnostic tests detect infection with very high sensitivity, and as concentration drops after treatment, it is a very good diagnostic method. (wikipedia.org)
- 17. Cañete R, Escobedo AA, Elena González M, Almirall P, Cantelar N. A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children. (ijtmgh.com)
- Effects of single-dose praziquantel on morbidity and mortality resulting from intestinal schistosomiasis. (edu.sd)
- The patient was given a single dose of praziquantel: 15 mg/kg body weight. (ispub.com)
- Group 2 and 3 were seperately given mebendazole and praziquantel, with single 60 mg/kg and 20 mg/kg doses, respectively, and Parasitological cure was documented when stool examination for Giardia lambilia was negative for 3 times within 7-10 days after therapy. (ijtmgh.com)
- Mebendazole and praziquantel were not as effective as metronidazole in the treatment of Giardiasis. (ijtmgh.com)
- No previous study has examined whether praziquantel treatment at 12-16 weeks gestation improves pregnancy outcomes or whether the use of a higher dose of praziquantel recommended to treat Asian schistosomiasis can be safely administered without adverse newborn or maternal outcomes. (news-medical.net)
- The recommended dose of Praziquantel is 2 milligrams per liter of water. (koivet.com)
- The present investigation was extended to include the effect of praziquantel administration on the liver and spleen of non infected and schistosome infected mice. (edu.qa)
- 1-To evaluate the effect of Praziquantel (PZQ) therapy on the regression of liver fibrosis in an endemic population. (edu.sd)
- Effect of praziquantel and liposome-incorporated praziquantel on peritoneal macrophage activation in mice infected with Mesocestoides corti tetrathyridia (Cestoda). (semanticscholar.org)
- Chemotherapy with praziquantel (PZQ) has been the cornerstone of schistosomiasis control over the last two decades. (biomedcentral.com)
- Mass drug administration (MDA) is a means of delivering safe and inexpensive essential medicines based on the principles of preventive chemotherapy, where populations or sub-populations are offered treatment without individual diagnosis. (royalsocietypublishing.org)
- Praziquantel is known to be one of the safest most effective pond fish medications available for treating a vast array of external and internal parasites. (best-planet.com)
- The fourth column lists recommended presumptive treatment for parasites (including malaria). (cdc.gov)
- Treatments include praziquantel for parasites, antibiotics and antifungal medicines. (reference.com)
- Initially, one group of five received praziquantel 60 mg/kg body weight in three divided doses orally while the remainder received an identically appearing placebo. (ajtmh.org)
- This study demonstrated the efficacy of taking two doses of oral PZQ for the treatment of urinary schistosomiasis among school children in Nigeria. (biomedcentral.com)
- and praziquantel (for schistosomiasis), 40 mg/kg divided in 2 doses for adults and children ≥ 4 yo. (cdc.gov)
- Two single oral doses of 40mg/kg praziquantel were given 6 weeks apart. (ac.zw)
- This 8-week trial includes four two-weekly standard doses of PZQ in the "intense treatment" intervention group and one standard dose of PZQ in the "standard treatment" control group. (springer.com)
- Fish tapeworms can be removed with a single treatment dose. (medlineplus.gov)
- Developed for superb results against all variants of Tapeworms, Equitape Horse Wormer uses the active ingredient Praziquantel to create a highly powerful and effective anti-Tapeworm treatment with no effects against other types of worms. (viovet.co.uk)
- It is an effective medication, exclusively meant for the treatment of tapeworms in cats . (petcarerx.com)
- Long tapeworms are sometimes found on the bottom of the treatment tank. (koivet.com)
- Patient Comments are not a substitute for professional medical advice, diagnosis, or treatment. (medicinenet.com)
- The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. (medlineplus.gov)
- A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. (medlineplus.gov)
- E granulosus is discussed separately from the other 3 species, notably Echinococcus multilocularis, which causes alveolar echinococcosis, because of marked differences in epidemiology, clinical features, diagnosis, and treatment. (medscape.com)
- The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
- Always seek the advice of a qualified physician for medical diagnosis and treatment. (medindia.net)
- Regulatory approval is being sought to use praziquantel (PZQ) to treat flukes infecting yellowtail kingfish (YTK), but accurate safety data were not available. (edu.au)
- What it is: Praziquantel is a bitter tasting powder which shows good absorption directly from the treated water, and then admirable clearance of various surface and internal flukes (trematodes) and internal worms in fish. (koivet.com)
- What it's good at: Because it's gentle, Praziquantel is, and always has been, the 'treatment of choice' for Flukes (trematodes) in fish. (koivet.com)
- It is entirely conceivable that the flukes can be eradicated with only one treatment. (koivet.com)
- Pros: The advantages are that Praziquantel is entirely benign to plants, fish and filter while clearing the Flukes and intestinal worms out rapidly and completely, even with fry. (koivet.com)
- Millions of women, many of whom are in a multi-year, cyclical pattern of pregnancy and breast-feeding, are denied praziquantel,' said Friedman. (news-medical.net)
- hence the effects of treatment during pregnancy are not fully known. (biomedcentral.com)
- Women were randomised to receive praziquantel or placebo during pregnancy. (biomedcentral.com)
- Praziquantel treatment during pregnancy boosted anti-worm IgG isotypes and to a lesser extent IgE, but these boosts were less pronounced than in women whose treatment was delayed until after delivery. (biomedcentral.com)
- S mansoni antigen-specific antibody levels and praziquantel-induced boosts in antibody levels were broadly suppressed during pregnancy, but this was not associated with major reduction in the efficacy of praziquantel. (biomedcentral.com)
- However, since the benefits and risks of treatment during pregnancy had not been studied, a WHO scientific working group in 2005 called for randomised, placebo-controlled trials of treatment during pregnancy for all species of human schistosomes in both low and high transmission areas [ 4 ]. (biomedcentral.com)
- Since 2006, two randomized controlled trials on the use of praziquantel during pregnancy have been conducted: one against S. mansoni in Uganda and the other against S. japonicum in the Philippines. (who.int)
- What is the efficacy of treatment for schistosomiasis (bilharzia) during pregnancy? (medscape.com)
- A retrospective study of 88 women with schistosomiasis who received praziquantel during pregnancy, in a mass treatment campaign, did not show an increase in the rate of abortion, preterm deliveries, or congenital abnormalities compared with untreated women. (medscape.com)
- The formulation and dosage schedule is designed to provide a minimum of 1.36 mg/lb (3 mg/kg) emodepside and 5.45 mg/lb (12 mg/kg) praziquantel based on body weight. (medi-vet.com)
- Standard treatment guidelines should be consulted for information on appropriate dosage forms. (who.int)
- Some meds however linger for a long time so be very careful in weighing your options which treatment to use and plan ahead your dosage schedule. (aquariacentral.com)
- PROFENDER Topical Solution [1.98% emodepside/7.94% praziquantel] is a clear yellow ready-to-use solution packaged in single unit dosing applicator tubes for topical (dermal) treatment of cats 8 weeks of age and older and weighing at least 2.2 lbs (1 kg). (medi-vet.com)
- The recommended minimum dose is 1.36 mg/lb (3 mg/kg) emodepside + 5.45 mg/lb (12 mg/kg) praziquantel as a single topical dose. (medi-vet.com)
- People with known hypersensitivity to butylhydroxyanisole, emodepside or praziquantel should administer the product with caution. (medi-vet.com)
- One hundred cases of paragonimiasis from Saraburi province, Thailand were studied with respect to epidemiology, clinical manifestations, radiography and treatment. (eurekamag.com)
- Antibody responses in serum and cerebrospinal fluid (CSF) samples from patients with active and chronic paragonimiasis and in sera from patients on whom follow-up studies were done after praziquantel treatment were analyzed using antigens of Paragonimus westermani prepared from eggs, metacercariae, juveniles of 4- and 7-week old, adult worms and recombinant protein of 28 kDa cruzipain-like cysteine protease (rPw28CCP). (parasitol.kr)
- The second was to enhance our understanding of schistosomiasis and its treatment with praziquantel in pre-school and school-aged children with a clinical dose-finding trial and complementary metabonomic investigations. (unibas.ch)
- Treatment currently focuses on adults and school-aged children, but many preschool children are also infected. (astellas.com)
- A newly established international public-private partnership (PPP) between TI Pharma, Merck KGaA (Darmstadt, Germany), Astellas Pharma Inc. and the Swiss Tropical and Public Health Institute ("Swiss TPH") has been launched to develop a new pediatric formulation of praziquantel to combat schistosomiasis - commonly known as bilharzia - in preschool children. (astellas.com)
- A pediatric formulation is desperately needed to develop an adequate treatment for the most vulnerable age group. (astellas.com)
- The objective of this partnership is to develop a formulation of praziquantel more suited to young children. (astellas.com)
- Astellas Pharma Inc. contributes to the development of the first ever pediatric formulation of praziquantel by utilizing its innovative pharmaceutical technologies that help improve convenience of use and functionality through the removal of praziquantel's bitter taste. (astellas.com)
- Treatment outcomes are better when surgery or PAIR ( Puncture, Aspiration, Injection of protoscolicidal agent and Reaspiration ) is combined with benzimidazole drugs given pre- and/or post-operation. (springer.com)
- Secondary outcomes include the difference in CR and intensity reduction rate between the intense and standard treatment groups as measured by the other diagnostic tests, as well as the accuracy of the different diagnostic tests, and the safety of PZQ. (springer.com)
- Clinically relevant drug resistance has not yet been described, but there is considerable heterogeneity in treatment outcomes, ranging from cure to only moderate egg reduction rates. (biomedcentral.com)
- Regular treatment of populations in endemic areas alleviates severe morbidity [ 5 ]. (biomedcentral.com)
- Like praziquantel, it promotes more severe damage of the dorsal tegument than of the ventral surface. (wikipedia.org)
- Treatment before significant damage or severe complications occur usually produces good results. (healthtap.com)
- In vivo it was more potent than praziquantel with an ED50 of 14.6 and 138.9 mg/kg against adult and juvenile stage worms respectively. (unibas.ch)
- Treatment for bladder worms is generally not recommended unless your cat is experiencing symptoms. (cat-world.com.au)
- Circulating anodic antigen (CAA) and circulating cathodic antigen (CCA) have levels correlating with the number of worms and have also been shown to clear within a few days or weeks after successful treatment. (clinicaltrials.gov)
- While you may not be able to determine which type of intestinal worms your dog has, keeping an eye out for these symptoms can help you determine if your dog may need treatment for intestinal worms. (wikihow.com)
- citation needed] Treatment with triclabendazole has been highly effective against the adult worms as well as various developing stages. (wikipedia.org)
- Authored by Jennifer F. Friedman, M.D., Ph.D., MPH, director of clinical studies for the Center for International Health Research at Rhode Island Hospital, the study found that praziquantel does not lead to adverse events for the pregnant woman or her newborn. (news-medical.net)
- The patient showed dramatic clinical improvement with high-dose praziquantel treatment. (ekjm.org)
- The aim of this work is to analyse the available data to answer clinical questions regarding medical treatment of CE. (springer.com)
- The aim of this study is to analyse available data to answer the following clinical questions regarding the medical treatment of CE: i) Could pharmacological treatment improve the results of surgical interventions? (springer.com)
- In 2006, WHO also stated the need for randomized controlled trials to assess the safety and efficacy of such treatment. (who.int)
- In these trials, praziquantel treatment of pregnant women had no significant effect on birth weight, appeared safe and caused minimal side-effects that were similar to those seen in treated non-pregnant subjects. (who.int)
- Having summarized the encouraging data, on efficacy, pharmacokinetics and safety, from these two trials and reviewed the safety data from non-interventional human studies, we recommend that all countries include pregnant women in praziquantel treatment campaigns. (who.int)
- A systematic search of PubMed (Medline), Cochrane Central Register of Controlled Trials (CENTRAL), BioMed, DARE (Database of Abstracts of Reviews of Effects), and Cochrane Plus databases was conducted without language restrictions to identify studies that assessed the efficacy of medical treatment of CE and had been published up to February 1, 2017. (springer.com)
- This recommendation was based on animal studies, as well as case reports of inadvertent or necessary treatment of pregnant women, which showed no evidence of adverse effects. (biomedcentral.com)
- No adverse effects of praziquantel administration during lactation have been reported. (medscape.com)
- If signs or symptoms of congestive heart failure occur or worsen during administration of TOLSURA, reassess the benefit and risk of continuing treatment [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS ]. (rxlist.com)
- Praziquantel is a newly developed drug effective in the treatment of schistosomiasis. (ajtmh.org)
- Using a step-by-step procedure, the most effective substance, praziquantel, was chosen from a total of approximately 400 compounds. (who.int)
- Praziquantel 25 my/kg body weight three times a day for 2 days gave a cure rate of 90%, mebendazole plus emetine hydrochloride gave a cure rate of 70% and mebendazole alone was not effective. (eurekamag.com)
- The treatment is safe and effective but carries important drawbacks such as its lack of efficacy against juvenile worm stages and its child-unfriendly bitter taste. (unibas.ch)
- A single treatment is effective and a second treatment should not be necessary. (medi-vet.com)
- What treatment has been effective for your bladder cancer? (medicinenet.com)
- Priority conditions are selected on the basis of current and estimated future public health relevance, and potential for safe and cost effective treatment. (who.int)
- Praziquantel is also an effective treatment for gill mites. (reference.com)
- What are some effective soil treatments against tomato blight? (reference.com)
- This is a monthly treatment, meaning to be effective, it has to be administered every month throughout the entire year, winter included. (petside.com)
- Praziquantel is not effective, and older drugs such as bithionol are moderately effective but also cause more side effects. (wikipedia.org)