A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
Therapy with two or more separate preparations given for a combined effect.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Substances that reduce the growth or reproduction of BACTERIA.
The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
The return of a sign, symptom, or disease after a remission.
A group of SESQUITERPENES and their analogs that contain a peroxide group (PEROXIDES) within an oxepin ring (OXEPINS).
A 4-aminoquinoline compound with anti-inflammatory properties.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A family of diphenylenemethane derivatives.
A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM). It is most prevalent in the tropics and subtropics.
A condition of substandard growth or diminished capacity to maintain normal function.
Elements of limited time intervals, contributing to particular results or situations.
A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
The ability of viruses to resist or to become tolerant to chemotherapeutic agents or antiviral agents. This resistance is acquired through gene mutation.
Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Substances that are destructive to protozoans.
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE.
Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
Arsenical used in trypanosomiases. It may cause fatal encephalopathy and other undesirable side effects.
The process of observing, recording, or detecting the effects of a chemical substance administered to an individual therapeutically or diagnostically.
A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
An anabolic steroid that has been used in the treatment of male HYPOGONADISM, delayed puberty in males, and in the treatment of breast neoplasms in women.
The quantity of measurable virus in a body fluid. Change in viral load, measured in plasma, is sometimes used as a SURROGATE MARKER in disease progression.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Drug regimens, for patients with HIV INFECTIONS, that aggressively suppress HIV replication. The regimens usually involve administration of three or more different drugs including a protease inhibitor.
A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
A republic in eastern Africa, south of SUDAN and west of KENYA. Its capital is Kampala.
A hemoflagellate subspecies of parasitic protozoa that causes Gambian or West African sleeping sickness in humans. The vector host is usually the tsetse fly (Glossina).
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
A species of gram-negative bacteria originally isolated from urethral specimens of patients with non-gonoccocal URETHRITIS. In primates it exists in parasitic association with ciliated EPITHELIAL CELLS in the genital and respiratory tracts.
An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC
Disease having a short and relatively severe course.
An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)
A metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Pathological processes involving the PHARYNX.
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.
Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Infections with bacteria of the genus STAPHYLOCOCCUS.
Voluntary cooperation of the patient in following a prescribed regimen.
A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects.
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
The giving of drugs, chemicals, or other substances by mouth.
Simultaneous resistance to several structurally and functionally distinct drugs.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis.
An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
A country consisting of the eastern half of the island of New Guinea and adjacent islands, including New Britain, New Ireland, the Admiralty Islands, and New Hanover in the Bismarck Archipelago; Bougainville and Buka in the northern Solomon Islands; the D'Entrecasteaux and Trobriand Islands; Woodlark (Murua) Island; and the Louisiade Archipelago. It became independent on September 16, 1975. Formerly, the southern part was the Australian Territory of Papua, and the northern part was the UN Trust Territory of New Guinea, administered by Australia. They were administratively merged in 1949 and named Papua and New Guinea, and renamed Papua New Guinea in 1971.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Cytochromes of the b group that have alpha-band absorption of 563-564 nm. They occur as subunits in MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
MYCOBACTERIUM infections of the lung.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs.
The practice of replacing one prescribed drug with another that is expected to have the same clinical or psychological effect.
The relationship between the dose of an administered drug and the response of the organism to the drug.
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
A broad-spectrum antimicrobial carboxyfluoroquinoline.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.
The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Proteins found in any species of protozoan.
A republic in central Africa, east of the REPUBLIC OF THE CONGO, south of the CENTRAL AFRICAN REPUBLIC and north of ANGOLA and ZAMBIA. The capital is Kinshasa.
Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Deoxyribonucleic acid that makes up the genetic material of protozoa.
Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
The ability of viruses to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance phenotype may be attributed to multiple gene mutation.
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).
1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. Often used in conjunction with iodinated organic compounds as contrast medium.
A pyrazine that is used therapeutically as an antitubercular agent.
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Infection of the lung often accompanied by inflammation.
A treatment method in which patients are under direct observation when they take their medication or receive their treatment. This method is designed to reduce the risk of treatment interruption and to ensure patient compliance.
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
A serotype of SALMONELLA ENTERICA that causes mild PARATYPHOID FEVER in humans.
A republic in eastern Africa, south of ETHIOPIA, west of SOMALIA with TANZANIA to its south, and coastline on the Indian Ocean. Its capital is Nairobi.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM.
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
The confinement of a patient in a hospital.
Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.
Non-steroidal chemical compounds with abortifacient activity.
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Formerly known as Siam, this is a Southeast Asian nation at the center of the Indochina peninsula. Bangkok is the capital city.
A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
An infant during the first month after birth.
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
A cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A republic in southern Africa, southwest of DEMOCRATIC REPUBLIC OF THE CONGO and west of ZAMBIA. Its capital is Luanda.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Tumors or cancer of the human BREAST.
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
A republic in southern Africa, south of DEMOCRATIC REPUBLIC OF THE CONGO and TANZANIA, and north of ZIMBABWE. Its capital is Lusaka. It was formerly called Northern Rhodesia.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Discontinuance of care received by patient(s) due to reasons other than full recovery from the disease.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Non-susceptibility of an organism to the action of the cephalosporins.
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Cluster survey evaluation of coverage and risk factors for failure to be immunized during the 1995 National Immunization Days in Egypt. (1/4460)

BACKGROUND: In 1995, Egypt continued to experience endemic wild poliovirus transmission despite achieving high routine immunization coverage with at least three doses of oral poliovirus vaccine (OPV3) and implementing National Immunization Days (NIDs) annually for several years. METHODS: Parents of 4188 children in 3216 households throughout Egypt were surveyed after the second round of the 1995 NIDs. RESULTS: Nationwide, 74% of children are estimated to have received both NID doses, 17% one NID dose, and 9% neither NID dose. Previously unimmunized (47%) or partially immunized (64%) children were less likely to receive two NID doses of OPV than were fully immunized children (76%) (P < 0.001). Other risk factors nationwide for failure to receive NID OPV included distance from residence to nearest NID site >10 minute walk (P < 0.001), not being informed about the NID at least one day in advance (P < 0.001), and residing in a household which does not watch television (P < 0.001). Based on these findings, subsequent NIDs in Egypt were modified to improve coverage, which has resulted in a marked decrease in the incidence of paralytic poliomyelitis in Egypt. CONCLUSIONS: In selected situations, surveys can provide important information that is useful for planning future NIDs.  (+info)


nvited commentary: vaccine failure or failure to vaccinate?  (+info)


aning of vaccine-induced immunity: is it a problem in Africa?  (+info)

Early mycological treatment failure in AIDS-associated cryptococcal meningitis. (4/4460)

Cryptococcal meningitis causes significant morbidity and mortality in persons with AIDS. Of 236 AIDS patients treated with amphotericin B plus flucytosine, 29 (12%) died within 2 weeks and 62 (26%) died before 10 weeks. Just 129 (55%) of 236 patients were alive with negative cerebrospinal fluid (CSF) cultures at 10 weeks. Multivariate analyses identified that titer of cryptococcal antigen in CSF, serum albumin level, and CD4 cell count, together with dose of amphotericin B, had the strongest joint association with failure to achieve negative CSF cultures by day 14. Among patients with similar CSF cryptococcal antigen titers, CD4 cell counts, and serum albumin levels, the odds of failure at week 10 for those without negative CSF cultures by day 14 was five times that for those with negative CSF cultures by day 14 (odds ratio, 5.0; 95% confidence interval, 2.2-10.9). Prognosis is dismal for patients with AIDS-related cryptococcal meningitis. Multivariate analyses identified three components that, along with initial treatment, have the strongest joint association with early outcome. Clearly, more effective initial therapy and patient management strategies that address immune function and nutritional status are needed to improve outcomes of this disease.  (+info)

Association of plasma fibrinogen concentration with vascular access failure in hemodialysis patients. (5/4460)

BACKGROUND: Elevated plasma fibrinogen is an important risk factor for coronary artery disease in the general population and patients with chronic renal failure. High plasma fibrinogen may trigger thrombus formation in arteriovenous fistulas. We performed a prospective, cohort study to evaluate the association of plasma fibrinogen concentration with vascular access failure in patients undergoing long-term haemodialysis. METHODS: Between September 1989 and October 1995, 144 patients underwent a vascular access operation. In March 1997, 102 patients (56 M, 46 F) who had been followed up for more than 18 months (median; 37 months, range; 18-102 months) were included in the study. The median age of the patients was 52 years (range; 19-78 years). In 35 patients, renal disease was secondary to diabetes mellitus. The type of vascular access was a polytetrafluoroethylene (PTFE) graft in 17 patients. Seventy-seven patients received recombinant human erythropoietin (r-HuEPO) therapy during the follow-up period. Plasma fibrinogen, albumin, total cholesterol, hematocrit, platelets and creatinine were measured at the time of operation. Vascular access failure was defined as the occurrence of complications requiring transluminal angioplasty, thrombolytic therapy or surgical repair. RESULTS: Thirty-eight patients had at least one vascular access failure and the incidence was 0.3 (range; 0-2.4) episodes per patient-year. The survival rate of vascular access was 78% (native fistula; 80%, PTFE graft; 71%) after 12 months and 70% (native fistula; 73%, PTFE graft; 51%) after 24 months. Older age, a PTFE graft, r-HuEPO therapy, higher hematocrit, lower albumin and higher fibrinogen levels were significantly associated with vascular access failure, whereas gender, diabetes mellitus, total cholesterol and platelet count were not. Plasma fibrinogen was inversely correlated with albumin (r=-0.38, P=0.001). The cumulative vascular access survival was significantly lower in patients with high plasma fibrinogen levels (> or = 460 mg/dl) compared with patients with low levels (< 460 mg/dl) (P=0.007). Independent risk factors for vascular access failure analysed by Cox's proportional hazards model were older age (RR; 1.36 by 10-year increment), higher fibrinogen level (RR; 1.20 by 100 mg/dl increment), PTFE graft (RR; 2.28) and r-HuEPO therapy (RR; 3.79). CONCLUSION: High plasma fibrinogen level is an independent risk factor for vascular access failure in haemodialysis patients.  (+info)

Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaounde, Cameroon. (6/4460)

The usefulness of an isotopic in vitro assay in the field was evaluated by comparing its results with the therapeutic response determined by the simplified WHO in vivo test in symptomatic Cameroonian patients treated with chloroquine. Of the 117 enrolled patients, 102 (87%) completed the 14-day follow-up, and 95 isolates obtained from these patients (46 children, 49 adults) yielded an interpretable in vitro test. A total of 57 of 95 patients (60%; 28 children and 29 adults) had an adequate clinical response with negative smears (n = 46) or with an asymptomatic parasitaemia (n = 11) on day 7 and/or day 14. The geometric mean 50% inhibitory concentration of the isolates obtained from these patients was 63.3 nmol/l. Late and early treatment failure was observed in 29 (30.5%) and 9 (9.5%) patients, respectively. The geometric mean 50% inhibitory concentrations of the corresponding isolates were 173 nmol/l and 302 nmol/l. Among the patients responding with late and early treatment failure, five isolates and one isolate, respectively, yielded a discordant result (in vivo resistance and in vitro sensitivity). The sensitivity, specificity, and predictive value of the in vitro test to detect chloroquine-sensitive cases was 67%, 84% and 86%, respectively. There was moderate concordance between the in vitro and in vivo tests (kappa value = 0.48). The in vitro assay agrees relatively well with the therapeutic response and excludes several host factors that influence the results of the in vivo test. However, in view of some discordant results, the in vitro test cannot substitute for in vivo data on therapeutic efficacy. The only reliable definition of "resistance" in malaria parasites is based on clinical and parasitological response in symptomatic patients, and the in vivo test provides the standard method to determine drug sensitivity or resistance as well as to guide national drug policies.  (+info)

Outcome and predictors of failure of highly active antiretroviral therapy: one-year follow-up of a cohort of human immunodeficiency virus type 1-infected persons. (7/4460)

The outcome and predictors of virologic treatment failure of highly active antiretroviral therapy (HAART) were determined for 271 human immunodeficiency virus (HIV)-infected protease inhibitor-naive persons. During a follow-up of 48 weeks after the initiation of HAART, 6.3% of patients experienced at least one new AIDS-defining event, and 3.0% died. Virologic treatment failure occurred in 40% (indinavir, 27%; ritonavir, 30%; saquinavir, 59%; ritonavir plus saquinavir, 32%; chi2, P=.001). Risk factors for treatment failure were baseline plasma HIV-1 RNA (odds ratio [OR], 1.70 per log10 copies increase in plasma HIV-1 RNA), baseline CD4 cell count (OR, 1. 35 per 100 CD4 cells/mm3 decrease), and use of saquinavir versus other protease inhibitors (OR, 3.21). During the first year of treatment, 53% of all patients changed (part of) their original HAART regimen at least once. This was significantly more frequent for regimens containing saquinavir (62%; 27% for virologic failure) or ritonavir (64%; 55% for intolerance) as single protease inhibitor.  (+info)

Isolated femoropopliteal bypass graft for limb salvage after failed tibial reconstruction: a viable alternative to amputation. (8/4460)

PURPOSE: Femoropopliteal bypass grafting procedures performed to isolated popliteal arteries after failure of a previous tibial reconstruction were studied. The results were compared with those of a study of primary isolated femoropopliteal bypass grafts (IFPBs). METHODS: IFPBs were only constructed if the uninvolved or patent popliteal segment measured at least 7 cm in length and had at least one major collateral supplying the calf. When IFPB was performed for ischemic lesions, these lesions were usually limited to the digits or small portions of the foot. Forty-seven polytetrafluoroethylene grafts and three autogenous reversed saphenous vein grafts were used. RESULTS: Ankle brachial pressure index (ABI) increased after bypass grafting by a mean of 0.46. Three-year primary life table patency and limb-salvage rates for primary IFPBs were 73% and 86%, respectively. All eight IFPBs performed after failed tibial bypass grafts remained patent for 2 to 44 months, with patients having viable, healed feet. CONCLUSION: In the presence of a suitable popliteal artery and limited tissue necrosis, IFPB can have acceptable patency and limb-salvage rates, even when a polytetrafluoroethylene graft is used. Secondary IFPB can be used to achieve limb salvage after failed tibial bypass grafting.  (+info)

Management of Virologic Treatment Failure. The approach to management and subsequent treatment of virologic treatment failure will differ depending on the etiology of the problem. While the causes of virologic treatment failure may be multifactorial, nonadherence plays a role in most cases. Assessment of a child with suspicion of virologic treatment failure should include evaluation of adherence to therapy and medication intolerance, confirmation that prescribed dosing is correct for all medications in the regimen, consideration of pharmacokinetic (PK) explanations of low drug levels or elevated and potentially toxic levels, and evaluation of suspected drug resistance (see Antiretroviral Drug-Resistance Testing in the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents). The main barrier to long-term maintenance of sustained virologic suppression in adults and children is incomplete adherence to medication regimens, with subsequent emergence of viral ...
Management of Virologic Treatment Failure. The approach to management and subsequent treatment of virologic treatment failure will differ depending on the etiology of the problem. While the causes of virologic treatment failure may be multifactorial, nonadherence plays a role in most cases. Assessment of a child with suspicion of virologic treatment failure should include evaluation of adherence to therapy and medication intolerance, confirmation that prescribed dosing is correct for all medications in the regimen, consideration of pharmacokinetic (PK) explanations of low drug levels or elevated and potentially toxic levels, and evaluation of suspected drug resistance (see Antiretroviral Drug-Resistance Testing in the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents). The main barrier to long-term maintenance of sustained virologic suppression in adults and children is incomplete adherence to medication regimens, with subsequent emergence of viral ...
CONTEXT: Presence of low-frequency, or minority, human immunodeficiency virus type 1 (HIV-1) drug resistance mutations may adversely affect response to antiretroviral treatment (ART), but evidence regarding the effects of such mutations on the effectiveness of first-line ART is conflicting.. OBJECTIVE: To evaluate the association of preexisting drug-resistant HIV-1 minority variants with risk of first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral virologic failure.. DATA SOURCES: Systematic review of published and unpublished studies in PubMed (1966 through December 2010), EMBASE (1974 through December 2010), conference abstracts, and article references. Authors of all studies were contacted for detailed laboratory, ART, and adherence data.. STUDY SELECTION AND DATA ABSTRACTION: Studies involving ART-naive participants initiating NNRTI-based regimens were included. Participants were included if all drugs in their ART regimen were fully active by standard HIV ...
Virologic failure occurs in a large proportion of individuals receiving treatment with combination antiretroviral therapy. Studies suggest that treatment interruption prior to initiation of a multiple-drug rescue regimen may improve virologic response in individuals who have failed several prior antiretroviral regimens. Other studies suggest there is a virologic benefit derived from using genotypic or phenotypic resistance testing in selecting salvage therapy regimens for patients failing antiretroviral therapy. This study tests the hypothesis that salvage regimens selected on the basis of HIV-1 resistance genotype, phenotype [AS PER AMENDMENT 02/19/02: virtual phenotype], and treatment history will be more effective if there is a period of treatment interruption before initiating that regimen.. Patients continue their antiretroviral therapy until randomization. Based on the results of the pre-entry genotype and phenotype [AS PER AMENDMENT 02/19/02: virtual phenotype] tests and treatment ...
Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy ...
Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy ...
1. Torres et al performed an RCT in 3 Spanish hospitals over 8 years. 120 patients with severe CAP (CRP , 150mg/l) were given intravenous bolus of 0.5 mg/kg per 12 hours of methylprednisolone or placebo for 5 days, started within 36 hours of hospital admission.Treatment failure was the primary outcome.. (Early treatment failure was development of shock, new need for mechanical ventilation , or death within 72 hours. Late treatment failure defined as worse CXR, persistence of severe respiratory failure, or any early treatment failure criteria between 72 hours and 120 hours.). There was less treatment failure in the steroid group (13 v 31%). Looking more closely it was the late treatment failure that was more affected, particularly the occurrence of septic shock. No statistically significant difference in hyperglycaemia.. Only 120 patients in 8 years raises concerns about recruitment and consequently external validity. Also there was no mortality difference between the groups - although the ...
Sputum samples from ten individuals were positive for acid-fast bacilli. Three of these individuals were HIV-positive, and one of these people was newly diagnosed with HIV thanks to the community health campaign.. Nine of the TB diagnoses were new; the other case had previously been detected at a local health centre. Six of the new cases had microscopy results suggesting their TB was highly contagious. Overall, 0.31% of people were newly diagnosed with TB. The number of people needed to screen using symptoms and microscopy to identify a single new case was 3024. The number of people with prolonged cough who required screening with microscopy to identity a new case was 320, the figure falling to 80 per case for HIV-positive people with chronic cough.. All nine people with newly detected TB were linked to care and initiated TB therapy. This treatment was completed by six people. One individual experienced treatment failure and initiated a second-line regimen; one individual was lost to follow-up; ...
Objectives: Better understanding of the dynamics of HIV reservoirs under ART is a critical step to achieve a functional HIV cure. Our objective was to assess the genetic diversity of archived HIV-1 DNA over 48 weeks in blood cells of individuals starting treatment with a dolutegravir-based regimen. Methods: Eighty blood samples were prospectively and longitudinally collected from 20 individuals (NCT02557997) including: acutely (n = 5) and chronically (n = 5) infected treatment-naive individuals, as well as treatment-experienced individuals who switched to a dolutegravir-based regimen and were either virologically suppressed (n = 5) or had experienced treatment failure (n = 5 ...
Hello and thanks for posting. Since you never really experienced treatment failure (or drug resistance), youd be considered on \
Some see admission of problems with bipolar disorder indicative of treatment failure. Bipolar pain doesnt indicate treatment failure. Breaking Bipolar blog by
High failure rate of OCZ SSDs yields answers that raise troubling questions - SSDs are like a bad drug. Theyre the best improvement one can make to a PC, but... My 4th OCZ SSD failed today at a remote site. With 4 out of 13 dr
View Notes - LAB 9 v2 from CS 1371 at Georgia Tech. LAB 9 NOTE: These labs are known for high failure rates. Therefore, if I show an example using data, a graph, etc yours may be totally different
Summer Sky Texas Inpatient Alcohol & Drug Rehabs, is relapse an Indicator of Treatment Failure, Medical Detox, 30-day rehab, 60-day rehab, 90-day rehabs
CAPE TOWN, South Africa -- The thiazolidinedione Avandia (rosiglitazone) has a more durable response than two older oral type 2 diabetes agents, but it was more expensive and had more side effects, re
We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time.Find out more ...
Many COVID drugs are failing. Natural medicine may hold the key-but can government cronyism be overcome? Action Alert! A large analysis has found that…
Another once-promising Alzheimer's drug has just been tossed on the pharmaceutical scrap heap. This time it's a drug called bapineuzumab. Like
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
I spent my morning unsuccessfully catching up on work. I was off to a good start, but then shooting pains started ripping through my left leg. At first I thought it might be a heart attack, but then I remembered...
TY - JOUR. T1 - Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy. AU - Lorch, Anja. AU - Beyer, Jörg. AU - Kramar, Andrew. AU - Einhorn, Lawrence H.. AU - Necchi, Andrea. AU - Massard, Christophe. AU - De Giorgi, Ugo. AU - Flechon, Aude. AU - Margolin, Kim A.. AU - Lotz, Jean Pierre. AU - Germa, Jose Ramon Lluch. AU - Powles, Thomas. AU - Kollmannsberger, Christian K.. AU - Bascoul-Mollevi, Caroline. PY - 2010/11/20. Y1 - 2010/11/20. N2 - Purpose: To develop a prognostic model in patients with germ cell tumors (GCT) who experience treatment failure with cisplatin-based first-line chemotherapy. Patients and Methods: Data from 1,984 patients with GCT who progressed after at least three cisplatin-based cycles and were treated with cisplatin-based conventional-dose or carboplatin-based high-dose salvage chemotherapy was retrospectively collected from 38 centers/groups worldwide. One thousand five hundred ...
Ekloef and Schmidt Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine2012, 20(Suppl 2):P10http://www.sjtrem.com/content/20/S2/P10 Community-acquired pneumonia: a comparisonof clinical treatment failure in patients treatedwith either penicillin or cefuroximeJosefin Ekloef*, Thomas A Schmidt From 4th Danish Emergency Medicine ConferenceRoskilde, Denmark. 25-26 November 2011 cefuroxime. Forty percent of the patients treated with National and local guidelines in the Emergency depart- penicillin experienced CTF compared to 17% in the ment (ED) at Holbaek hospital recommend penicillin as group treated with cefuroxime (p=0.347). Patients were first-line treatment of community-acquired pneumonia followed for 9 days. At 5 days, a survival rate without (CAP). Nevertheless, the use of cefuroxime seem to be CTF was estimated to 0,75 for cefuroxime and 0.54 for substantial when admitting patients with CAP ...
Southern Africa has the highest prevalence of HIV worldwide, and South Africa has the highest number of HIV infected people. South Africa and other resource-limited countries provide antiretroviral therapy (ART) for people with HIV, with limited, standardized regimens for first line and second line. Patients who fail first line treatment are put on second line regimens, yet options for third line are very limited. The first study looks at predictors of first line treatment failure in South Africa and develops a predictive model that can estimate absolute risk of treatment failure over 5 years on ART, given a baseline profile of clinical and demographic factors. The model was developed with accelerated failure time models, using predictors that maximized discrimination between patients. The model can be used to identify patients who need adherence interventions, and to estimate how changes in baseline parameters in the population influence long-term need for second line ART. The second study ...
Treatment failure is a serious problem facing some national tuberculosis [TB] control programmes. Irregularity of treatment is a factor that can lead to treatment failure. A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. We interviewed 119 people with treatment failure and an equal number of cured cases [controls] and their families regarding sociodemographic characteristics, information about TB, information about drugs, treatment compliance, family support and patient-family interaction. Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid ...
Our study indicates that 7% of patients with type 1 autoimmune hepatitis deteriorate during corticosteroid therapy and that treatment failure is associated with onset at an early age, acute presentation, hyperbilirubinemia, HLA DRB1*03, and a MELD score of at last 12 points. We could not ascribe the treatment failure to transition of the autoimmune hepatitis to another condition, and only 1 patient developed fatty liver disease, in whom treatment failure might have related to a superimposed or concurrent disease. Treatment failure was associated with a poor prognosis despite high-dose corticosteroid treatment, 7 patients (50%) either died of liver-related causes or required transplantation, and only 2 patients (14%) achieved remission.. Previous studies have indicated the importance of using disease severity, shown by histological pattern and laboratory features, to identify patients who have a poor prognosis if they are untreated.56 These findings, however, have not reliably identified those ...
Background: Timely detection of treatment failure with subsequent switch to second-line regimen reduces mortality among HIV infected people on antiretroviral therapy (ART). This paper aims to investigate the detection of immunological treatment failure and switch rate to second line regimen in Ethiopia. Methods: A retrospective cohort study was conducted among HIV infected patients (age > 15 years) who initiated ART between 2007 and 2009. The required data were collected from patient registers and formats. Data were entered and validated using EpiData software and then exported to SPSS version 20.0 for analysis. Odds ratio with 95 % CI was used to assess whether immunological treatment failure was associated with experiencing unfavorable treatment outcomes (death or lost to follow up). Results: Records of 293 patients were reviewed with a total of 1545 Person-Years of Observation (PYO). The median baseline CD4 count was 115 cells/mm3 (IQR: 64-176). A total of 46 (15.7 %) patients experienced ...
Good clinical activity for lenalidomide in R/R MCL patients after ibrutinib therapy failure Multicenter observational MCL-004 study
article{a788131c-c8d3-451e-9c12-43ec2f617e36, abstract = {,p,Background: Early identification of virological failure (VF) limits occurrence and spread of drug-resistant viruses in patients receiving antiretroviral treatment (ART). Viral load (VL) monitoring is therefore recommended, but capacities to comply with this are insufficient in many low-income countries. Clinical algorithms might identify persons at higher likelihood of VF to allocate VL resources. Objectives: We aimed to construct a VF algorithm (the Viral Load Testing Criteria; VLTC) and compare its performance to the 2013 WHO treatment failure criteria. Methods: Subjects with VL results available 1 year after ART start (n = 494) were identified from a cohort of ART-naïve adults (n = 812), prospectively recruited and followed 2011-2015 at Ethiopian health centres. VF was defined as VL≥1000 copies/mL. Variables recorded at the time of sampling, with potential association with VF, were used to construct the algorithm based on ...
CrossRefexternal icon PubMedexternal icon https://xo-review.com/maxalt-online-usa/ About maxalt serotonin Healthy People. Mumps Outbreaks Still OccurAfter the U. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. You should avoid travel to the extent of such systems include health department website. Testing the weathering explanation for experiencing flu symptoms for the five CDC Best Practice categories separately, we found real per capita spending on tobacco control programs and directly funded city health departments immediately if you are leaving the CDC rapid development of the 30 Days to Slow the Spread of SARS-CoV-2 viral RNA is unlikely to affect many areas.. Other common precipitating circumstances of possible clinical treatment failure is highly suspected, consider maxalt serotonin specialized testing to ensure that you are leaving the CDC website. As an alternative to colonoscopy and any venues where the people you know during the ...
Primary objective To investigate the H. pylori eradication rate obtained by each second-line regimen, stratifying these results by the first-line treatment previously used.. Secondary objectives To study the effect on the eradication success rate of different doses of the drugs used in the same type of therapy and the effect of the length of the therapies. Moreover, we will study the differences in the efficacy of treatments by sub-analysis of the following factors:. ...
Antiretroviral therapy; Immunological failure; Loss to follow-up; Malawi; Marginal structural models; Mortality; Second-line therapy; Treatment failure; Viral load monitoring; ...
The Haematology Department Protocols and Guidelines (the Red Book) are intended as a guide for registered health professionals to communicate guidelines and share best practices with supporting health professionals within New Zealand district health boards. They are not intended to be provided to or used as a reference for patients or non-registered health professionals. All health professionals must exercise their own clinical judgement and use pertinent clinical data when treating patients. The authors and editors of this publication have checked with sources believed to be reliable in their effort to provide information that is complete and in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical science, neither the authors, editors, publisher, nor any other party who has been involved in preparing or publishing this work warrants that the information contained in it is accurate or complete in every respect. ...
(2015) Teshome, Tefera. BMC Immunology. Background: Timely detection of treatment failure with subsequent switch to second-line regimen reduces mortality among HIV infected people on antiretroviral therapy (ART). This paper aims to investigate the detection of immunological treatment failure and ...
Diagnosed with leukemia this year 2010, she experienced treatment that put her in remission, only to have her cancers come back a year . 5 later, more stubborn
Health, ...TUESDAY April 19 (HealthDay News) -- About 1 in 8 children infected w...That drug failure rate is higher than in adults and highlights the cha...Virological failure occurs when drugs can no longer reduce the amount ...The study included more than 1000 HIV-positive children in several Eu...,Children,With,HIV,at,Higher,Risk,of,Drug,Resistance,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
AUTHOR = {Lehmann, Clara and D{\a}umer, Martin and Bousaad, Ibrahim and Sing, Tobias and Beerenwinkel, Niko and Lengauer, Thomas and Schmeisser, Norbert and Wyen, Christoph and F{\a}tkenheuer, Gerd and Kaiser, Rolf ...
Bamlanivimab was authorized for use in relation to the COVID-19 pandemic, in accordance with the Interim Order Respecting the Importation, Sale and Advertising of Drugs for Use in Relation to COVID-19. The CPM for bamlanivimab was updated on 14 April 2021 with information concerning SARS-CoV-2 variants of concern.
This is another Pavilion G7 model, with assorted HIGH failures encountered during certification of 12.04.2 with various tests that use fwts. I have attached the batch run log and the suspend_30_cycles log. There were also errors in the Hibernate log, but they were identical to the ones in the suspend log regaring hp_wmi ProblemType: Bug DistroRelease: Ubuntu 12.04 Package: linux-image-3.5.0-25-generic 3.5.0-25.39~precise1 ProcVersionSignature: Ubuntu 3.5.0-25.39~precise1-generic Un...
Low-level HIV viral load, above the limit of detection, is an important warning signal for future treatment failure and World Health Organization guidelines on spotting treatment failure need to be revised to encourage greater vigilance and swifter action by healthcare providers in lower- and middle-income settings, investigators report in The Lancet Infectious Diseases. The study ...
While the new treatments for hepatitis C have improved dramatically in terms of cure rates and side effects (and pharmaceutical companies bottom-line), there are still patients who do not respond, especially those with genotype 3. A recent study (Hepatology 2015; 61: 56-65) has provided some information into why this is happening. A division of the…
Exosomes have diameter within the range of 30-100nm and spherical to cup-shaped nanoparticles with specific surface molecular characteristics, such as CD9 and
North Jersey Health & Wellness specializes in treating patients with a wide variety of mental illnesses, health issues and more. With 4 convenient locations, NJHW is the perfect practice for you and your family.
This thesis will explore research done to date on Bad Therapy, in an attempt to identify what are the common causes of therapy failure and typical therapy mistakes. There is a wide body of literature and research that ...
RePosting SGP / iOptron CEM-60EC Meridian Flip Failure - posted in Mounts: I have another thread going on this enigma. I am posting again to possibly get new ideas as to the ongoing flip failure. I appreciate all the help in the other thread deeply...but it hasnt cured the problem. I am sitting at my pier with a bunch of daylight meridian targets ready to try anything before nightfall. Here is the log from the latest failure (only the flip failure section) and a link here to the oth...
Failure is a part of our life except for the lucky ones but im pretty sure that no one ever did not experience such. Experiencing it was a painful thing yet in the end when everything is already ok we realize that everything happens for a reason and that everything happens for a purpose. we might not know it that that point in time but sooner or later youll find out. Failure is just passing everything will just go as it should be. take time to reflect and discern what to do next time to avoid failure this is only one thing is for sure, through failure we will learn from our mistakes, there will be many things that we discover in our self and that somehow will know that we are strong to accept such pain. In failure there is a opportunity to improve and be better the next time ...
Having battled - unsuccessfully - with full-blown CFS for about 5 years, I hooked up with a good specialist and have managed to pull myself largely out...
After years of unsuccessfully trying to have kids, this womans sister decided to carry her baby for her. Little did they know a miracle had happened.
Revealed: The Secret of Famous People.Why Failure is Good For Success. It May Not Be The Nicest of Things That Could Ever Happen To You. Yet, Failure is Pivotal to Ones Success. Dont Believe Me? Let me Show You How Failure Turned These Ordinary People Into Extraordinary People.
Its easy to be philosophical about failure when advising someone else, but things look different when youre facing a faux pas, fumble, or f***-up of your own. Let me offer some perspective from a recent experience.
Failure to thrive means that a child is not growing as he or she should. Psychological, social, or economic problems within the family almost always play a role in this condition.
Between Failures is a slice-of-life webcomic following the (somewhat under-motivated and decidedly sarcastic) staff of a chain bookstore created by Jackie Wohlenhaus.
Between Failures is a slice-of-life webcomic following the (somewhat under-motivated and decidedly sarcastic) staff of a chain bookstore created by Jackie Wohlenhaus.
Hello all, its exactly as the title says, I feel like Im doomed to failure. Im 23 and still not entirely certain what I want ...
Sometimes trying your best isnt enough; when the situation demands it, you need to be perfect. Sometimes trying your best isnt enough; when the situation demands it, you need to be perfect. For
I started with Windows XP , Office 2007 and IE.... Firefox was not installed nor ever was. I did install it though to do the HKEY classes root\firefox\ddexec\ regsitry value clearing ideas as found...
Hey all, Some of you may have heard me before but now that I have tried EVERYTHING I know that something is just not right and I need to know if I am Alone...
Ali, S; Lally, EV (November 2009). "Treatment failure gout". Medicine and health, Rhode Island. 92 (11): 369-71. PMID 19999896. ... Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can ...
Time to treatment > 4 hours? Yes (+1) What Does This Score Mean? Prior heart failure? Yes (+2) History of atrial fibrillation? ... TIMI 10B compared the angiographic efficacy and safety of several doses of TNK with front loaded rtPA for the treatment of ST ... ASSENT I-(TIMI 10C) compared the safety of several doses of TNK-tPA with rtPA for the treatment of ST elevation myocardial ... TIMI 12 evaluated the safety and efficacy of the oral GP IIb/IIa inhibitor sibrafiban for the treatment of patients with a ...
Ali S, Lally EV (November 2009). "Treatment failure gout". Medicine and Health, Rhode Island. 92 (11): 369-71. CiteSeerX 10.1. ... There are several types of medications that are used for the treatment of arthritis. Treatment typically begins with ... Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be ... Treatment options vary depending on the type of arthritis and include physical therapy, exercise and diet, orthopedic bracing, ...
Ali, S; Lally, EV (November 2009). "Treatment failure gout". Medicine and Health, Rhode Island. 92 (11): 369-71. PMID 19999896 ... "Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: ... Without treatment, an acute attack of gout usually resolves in five to seven days; however, 60% of people have a second attack ... Without treatment, episodes of acute gout may develop into chronic gout with destruction of joint surfaces, joint deformity, ...
Once there is reduced left ventricular ejection fraction and symptoms of heart failure, the prognosis is typically poor. The ... Play media Prevention of CAV progression is important as once developed, CAV existing treatments are often ineffective. ... Hunt, Sharon A. (2017-11-27). "Cardiac Allograft Vasculopathy: It Really Has Changed Over Time". JACC: Heart Failure. 5 (12): ... The other major causes of death following heart transplantation include graft failure, organ rejection and infection. People ...
... diagnosis and treatment". Heart Failure Reviews. 20 (2): 179-191. doi:10.1007/s10741-014-9452-9. ISSN 1573-7322. PMID 25030479 ... Besides these drugs, a gene therapy treatment is in clinical trials, with the technology licensed to AvroBio. Other treatments ... End-stage kidney failure in those with Fabry disease typically occurs in the third decade of life, and is a common cause of ... The first treatment for Fabry's disease to be approved by the US FDA was Fabrazyme (agalsidase beta, or alpha-galactosidase) in ...
... heart failure management; cardiac rehabilitation; and enhanced external counterpulsation (EECP) for treatment of chest pain. In ... Lourdes is a state-certified Primary Stroke Center for rapid and effective treatment of stroke patients, from initial diagnosis ...
Kidney failure. *Shaken baby syndrome. Treatment[edit]. Treatment is supportive.[1] Mannitol may be used to help with the brain ... Treatment is supportive.[1] Mannitol may be used to help with the brain swelling.[2] ...
Treatment is first targeted at the specific metabolic disorder. Acute kidney failure prior to chemotherapy. Since the major ... Acute kidney failure after chemotherapy. The major cause of acute kidney failure in this setting is hyperphosphatemia, and the ... due to hyperuricosuria has been a dominant cause of acute kidney failure but with the advent of effective treatments for ... but TLS can be triggered in cancer patients by steroid treatment alone, and sometimes without any treatment-in this case the ...
Anand, I. S.; Florea, V. G. (2001). "High Output Cardiac Failure". Current Treatment Options in Cardiovascular Medicine. 3 (2 ... Treatment is by thiamine supplementation, either by mouth or by injection.[1] With treatment symptoms generally resolve in a ... Treatment[edit]. Many people with beriberi can be treated with thiamine alone.[42] Given thiamine intravenously (and later ... In the acute form, the baby develops dyspnea and cyanosis and soon dies of heart failure. These symptoms may be described in ...
2015). "Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea". JACC: Heart Failure. 3 (5): 360-369. doi:10.1016/j ... This provides a much better treatment of the disorder than stimulation that is based on an estimate of when the seizure might ... In practice, a medical treatment could introduce thousands of neural dust devices into human brains. The term is derived from " ... While vagal nerve stimulation is often a target area for treatment of epileptic seizures, there has been research into the ...
... multiple treatment failures...multiple times on probation...served previous jail or prison sentences...driven by their ... Her parents told her that the charges would be dropped if she agreed to check into an out-of-town drug treatment program, away ... Her parents got her into treatment programs several times, but it didn't help. She got a job at a restaurant/bar and started ... The sanctions of the judge are viewed as part of "treatment", not the imposition of a sentence. Judge Williams insisted that ...
... a heart station for diagnosis and treatment of heart disease; a heart failure clinic; heart, kidney, liver, pancreas, cornea ... University Heart for the diagnosis and treatment of heart disease; a heart failure clinic; a comprehensive stroke center; ... With a total of 1,003 beds, including Holmes County and Grenada locations, UMMC is the largest diagnostic, treatment and ... Recognized for an atypical treatment regime that functionally cured a baby born with HIV in 2010. Arthur Guyton, physiologist; ...
Torsney, P.J. (November 1973). "Treatment failure: insect desensitization. Case reports of fatalities". The Journal of Allergy ... Emergency treatment is only needed if a person is showing signs of a severe allergic reaction. Prior to calling for help, stung ... The nature of treatment for a Myrmecia sting depends on the severity of stingose, and the use of antihistamine tablets are ... However, fatal failures were reported, and this led to scientists to research for alternative methods of desensitisation. ...
Bramwell, C. (20 November 1937). "Treatment of heart failure". Br Med J. 2 (4011): 1005-1008. doi:10.1136/bmj.2.4011.1005. PMC ... with A. Morgan Jones: Bramwell, C.; Jones, A. M. (July 1944). "Acute left auricular failure". Br Heart J. 6 (3): 129-134. doi: ... Bramwell, C. (1 June 1935). "Treatment of heart disease in pregnancy". Br Med J. 1 (3882): 1132-1133. doi:10.1136/bmj.1.3882. ...
Anand, I. S.; Florea, V. G. (2001). "High Output Cardiac Failure". Current Treatment Options in Cardiovascular Medicine. 3 (2 ... Treatment is by thiamine supplementation, either by mouth or by injection. With treatment, symptoms generally resolve in a ... In the acute form, the baby develops dyspnea and cyanosis and soon dies of heart failure. These symptoms may be described in ... It is sometimes fatal, as it causes a combination of heart failure and weakening of the capillary walls, which causes the ...
"Treatment failure in osteoporosis". Osteoporosis International. 23 (12): 2769-2774. doi:10.1007/s00198-012-2093-8. hdl:11343/ ... and offer concrete advantages from the point of view of short-term follow-up of patients undergoing therapeutic treatments. ...
Golden, David B. K. (27 November 1981). "Treatment Failures With Whole-Body Extract Therapy of Insect Sting Allergy". JAMA: The ... Torsney, P.J. (November 1973). "Treatment failure: insect desensitization. Case reports of fatalities". The Journal of Allergy ... Emergency treatment is needed in a case of a severe allergic reaction. Before calling for help, laying a person down and ... Other treatments include washing the stung area with soap and water, and if continuous pain remains for several days, ...
This may require antibiotic treatment or removal of the device. Mechanical failure is uncommon. Ports placed through the ... To administer treatment or to withdraw blood, a health care professional will first locate the port and disinfect the area, ... Then, treatment will begin. The implantation procedure itself is considered minor, and is typically performed with both local ... Many patients are asymptomatic but the mechanical failure is discovered because of an inability to flush or withdraw fluids ...
New treatment methods are actively being researched in regards to the treatment of heart failure and specific cardiac ... The majority of treatment is aimed at preserving heart function and treating heart failure symptoms. Light chain (AL-CM) ... Familial (ATTRm-CM) Treatment: In recent years there have been developments in the treatment of Familial/Transthyretin cardiac ... Amyloid deposition in the heart causes restrictive diastolic heart failure that progresses to systolic heart failure. Cardiac ...
"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure" (PDF). Eur Heart J. 10 (10): 933-89. doi: ... Congestive heart failure is the most common reason for fluid overload. Blood containing excess salt and water is withdrawn from ... 2009). "2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in ... Fluid overload can be caused by many reasons, including heart failure, liver cirrhosis, hypertension and certain kidney ...
Ingelfinger, Julie R (16 November 2017). "Diuretic Treatment in Heart Failure". The New England Journal of Medicine. 377 (20): ... For those with underlying renal impairment or severe heart failure, up to 160 to 200 mg bolus dose can be given. Hypertension ... They are primarily used in medicine to treat hypertension and edema often due to congestive heart failure or chronic kidney ... Loop diuretics may also precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor-the so-called ...
... and the treatment of the condition that caused the azotemia. Kidney failure Nephrology Kumar, Vinay; Fausto, Nelson; Fausto, ... Prompt treatment of some causes of azotemia can result in restoration of kidney function; delayed treatment may result in ... In congestive heart failure (a cause of pre-renal azotemia) or any other condition that causes poor perfusion of kidneys, the ... Causes include kidney failure, glomerulonephritis, acute tubular necrosis, or other kidney disease. The BUN:Cr in renal ...
These treatments are biologically implausible and the clinical tests have shown they don't do anything at all in human beings. ... hawthorn for congestive heart failure; guar gum for diabetes. In our book More Good Than Harm? ... ethicist Kevin Smith and I ... In a review of Trick or Treatment in the New England Journal of Medicine, Donald Marcus described Ernst as "one of the best ... ISBN 978-0-593-06129-9 (The same book published in the US is called Trick or Treatment: The Undeniable Facts about Alternative ...
Leonidas and Eudoxia Mamas report six cases of premature ovarian failure. After two to six months of treatment with DHEA (Two ... Kalantaridou SN, Braddock DT, Patronas NJ, Nelson LM (July 1999). "Treatment of autoimmune premature ovarian failure". Hum. ... This treatment protocol has also reversed some cases of iatrogenic POF caused by full body radiation treatment. While the ... Variable success rate with treatment, very few controlled studies, mostly case reports. Treatment success strongly tends to ...
... failure to provide medical treatment; verbal, physical and psychological abuse; separation of family members and dangerous ... "illegal immigrants deserve the same constitutionally-mandated humane treatment of citizens and legal residents". In 1998, ... Amnesty International investigated allegations of ill-treatment and brutality by officers of the Immigration and Naturalization ...
Prevalence and treatment patterns of diastolic filling abnormalities in the elderly. Journal of Heart Failure 1997; 4(1): 110. ... Cost-effectiveness of nurse-led disease management for heart failure in a racially diverse urban community. Annals of Internal ...
Little M (2005). "Failure of magnesium in treatment of Irukandji syndrome". Anaesth Intensive Care. 33 (4): 541-2. PMID ... J.Tibballs, G. Hawdon, K. Winkel (2001). "Mechanism of cardiac failure in Irukandji syndrome and first aid treatment for stings ... Treatment[edit]. Similar to other box jellyfish stings, first aid consists of flushing the area with vinegar to neutralize the ... "Jellyfish Sting Treatment". WebMD. 2013. Archived from the original on 18 May 2015. Retrieved 10 May 2015.. ...
Treatment of chronic kidney failure is dependent on the type of kidney failure and may involve dialysis. ... Treatment of related hyperviscosity syndrome may be required to prevent neurologic symptoms or kidney failure.[69][70] ... Treatment[edit]. Treatment is indicated in myeloma with symptoms. If there are no symptoms, but a paraprotein typical of ... Supportive treatment[edit]. Adding physical exercises to the standard treatment for adult patients with haematological ...
Resistant varieties accumulate, and treatment failure finally occurs. See also[edit]. *Dysphania ambrosioides, an herb native ... Treatment with an antihelminthic drug kills worms whose phenotype renders them susceptible to the drug, but resistant parasites ... The ability of parasites to survive treatments that are generally effective at the recommended doses is a major threat to the ... This is especially true of nematodes, and has helped spur development of aminoacetonitrile derivatives for treatment against ...
The treatment of bilateral coronal synostosis shows a high degree of overlap with treatment of unilateral coronal synostosis; ... The primary failure is the absence of growth of the brain, rendering the sutures of the cranial vault useless.[16] As a ... TreatmentEdit. The primary goal of surgical intervention is to allow normal cranial vault development to occur.[42] This can be ... The treatment of pansynostosis comprises the expansion of the anterior cranial vault, as well as the posterior cranial vault.[ ...
Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA. December 2011, 306 (23): 2594-605. PMC ... Successful!) Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1. ...
Metformin is generally recommended as a first line treatment as there is some evidence that it decreases mortality;[7][25][104] ... Hyperosmolar hyperglycemic state, diabetic ketoacidosis, heart disease, strokes, diabetic retinopathy, kidney failure, ... O'Gorman DJ, Krook A (September 2011). "Exercise and the treatment of diabetes and obesity". The Medical Clinics of North ... Type 2 diabetes is largely preventable by staying a normal weight, exercising regularly, and eating properly.[1] Treatment ...
experienced a failure of an LNG tank.[120] 128 people perished in the explosion and fire. The tank did not have a dike ... The process begins with the pre-treatment of a feedstock of natural gas entering the system to remove impurities such as H2S, ... Failure to remove such acidic molecules, mercury, and other impurities could result in damage to the equipment. Corrosion of ...
The results of the study showed that the most effective treatment was the three drug treatment. After 24 weeks of treatment, 24 ... which sometimes may lead to more severe condition including kidney failure ... Furthermore, it is no longer recommended to use in the United States for initial treatments due to pill burden and risk of ... From then on, indinavir used with dual NRTIs set a new standard for treatment of HIV/AIDS. Protease inhibitors changed the ...
a) Misinterpreted natural course - the individual gets better without treatment. b) Placebo effect or false treatment effect - ... failure to use or delay in using conventional science-based medicine has caused deaths.[171][172] ... Treatment delay. Alternative medicine may discourage people from getting the best possible treatment.[169] Those having ... There are also reasons why a placebo treatment group may outperform a "no-treatment" group in a test which are not related to a ...
He suffered from aortic stenosis and no longer had access to follow-up treatment for his earlier cancer.[391] A stroke left him ... The failure of Cambodian troops in the Eastern Zone to successfully resist the Vietnamese incursion made Pol Pot suspicious of ... On 15 April 1998, Pol Pot died in his sleep, apparently of heart failure.[398] His body was preserved with ice and formaldehyde ... fearing that they would be criticised for failure.[275] The government became aware of this, and by the end of 1976 Pol Pot ...
In conclusion, HMB treatment clearly appears to be a safe potent strategy against sarcopenia, and more generally against muscle ... Muscle atrophy results from a co-morbidity of several common diseases, including cancer, AIDS, congestive heart failure, COPD ( ... In conclusion, HMB treatment clearly appears to be a safe potent strategy against sarcopenia, and more generally against muscle ... A growing body of evidence supports the efficacy of HMB as a treatment for reducing, or even reversing, the loss of muscle mass ...
Sepsis is caused by overwhelming response to an infection and leads to tissue damage, organ failure, and even death. The ... van der Poll T, Opal SM (2009). "Pathogenesis, treatment, and prevention of pneumococcal pneumonia". Lancet. 374 (9700): 1543- ... Main article: Pneumococcal infection § Treatment. Resistant Pneumococci strains are called penicillin-resistant Pneumocci (PRP) ...
While there is no approved[by whom?] treatment for Ebola as of 2019[update],[9] two treatments (REGN-EB3 and mAb114) are ... Dialysis may be needed for kidney failure, and extracorporeal membrane oxygenation may be used for lung dysfunction.[33] ... Treatment is primarily supportive in nature.[135] Early supportive care with rehydration and symptomatic treatment improves ... While there is no approved treatment for Ebola as of 2019[update],[9] two treatments (REGN-EB3 and mAb114) are associated with ...
... cancer treatment; sickle cell anemia; sepsis; congestive heart failure; chronic obstructive pulmonary disease; and ... "Journal of Substance Abuse Treatment. 89: 75-86. doi:10.1016/j.jsat.2018.04.002. PMC 5964257. PMID 29706176.. ... A 2017 study found that Medicaid expansion, by increasing treatment for substance abuse, "led to a sizeable reduction in the ... Due to the high costs associated with HIV medications, many patients are not able to begin antiretroviral treatment without ...
This is one of the points made in Lord's (1953) satirical paper On the Statistical Treatment of Football Numbers.[17] ... Lord, Frederic M. (December 1953). "On the Statistical Treatment of Football Numbers". American Psychologist. 8 (12): 750-751. ... "On the Statistical Treatment of Football Numbers" (PDF). American Psychologist. 8 (12): 750-751. doi:10.1037/h0063675 ... Accelerated failure time (AFT) model. *First hitting time. Hazard function. *Nelson-Aalen estimator ...
Treatment[edit]. The flow of blood normally stops when the blood clots, which may be encouraged by direct pressure applied by ... Heart failure (due to an increase in venous pressure). *Hematological malignancy (such as leukemia) ... Guarisco JL, Graham HD (1989). "Epistaxis in children: causes, diagnosis, and treatment". Ear Nose Throat J. 68 (7): 522, 528- ... The drugs oxymetazoline or phenylephrine are widely available in over-the-counter nasal sprays for the treatment of allergic ...
In 2010 it was approved by the European Commission for maintenance treatment after initial treatment of follicular lymphoma.[45 ... Tumor lysis syndrome, causing acute renal failure. *Infections *Hepatitis B reactivation. *Other viral infections ... 30 to 400 hours (varies by dose and length of treatment). Excretion. Uncertain: may undergo phagocytosis and catabolism in RES ... "Rituximab Treatment of Patients with Severe, Corticosteroid-Resistant Thyroid-Associated Ophthalmopathy". Archived from the ...
... s Sex Offender Treatment and Evaluation Project (SOTEP)". Sexual Abuse: A Journal of Research and Treatment. 17: 79-107. doi: ... "Failure of a Token Economy, The 38 Federal Probation 1974". Retrieved 10 July 2016. Haynes, Robert L.; Marques, Janice K. (1 ... Initial research and treatment programs aimed at understanding and reducing the risk of reoffense in sexual offenders. In the ... "Forensic treatment in the United States: A survey of selected forensic hospitals". International Journal of Law and Psychiatry ...
This results in a delay of treatment, which can be detrimental to patients in need of immediate medical attention. Most of ... Introducing breast milk substitutes to infants before age 6 months can contribute to breastfeeding failure. Substitutes, such ...
Muñoz M, Rosso M, Coveñas R (2010). "A new frontier in the treatment of cancer: NK-1 receptor antagonists". Current Medicinal ... The failure of clinical proof of concept studies, designed to confirm various preclinical predictions of efficacy, is currently ... and that NK1RAs may be useful in the treatment of several cancer types.[42][43][44][45] ... and for which current treatments are absent or in need of improvement, abrogation of the SP-NK1 system continues to receive ...
Salih, F. M. (2001). "Can sunlight replace phototherapy units in the treatment of neonatal jaundice? An in vitro study". ... ଯକୃତ ଅକ୍ଷମତା (hepatic failure) ଯୋଗୁ କାମଳ ହୋଇଛି ।. ICD-10. R17.. ICD-9. 782.4. ... Bassari, R; Koea, JB (7 February 2015). "Jaundice associated pruritis: a review of pathophysiology and treatment". World ...
Treatment of spontaneous abortions[change , change source]. Usually, no treatment is needed for a miscarriage. However, ... of those using condoms reported failure through slipping or breakage.[34] The Guttmacher Institute estimated that "most ... Breast Cancer Research and Treatment 2 (1): 5-73. doi:10.1007/BF01805718. PMID 6216933. ...
Hypothyroidism~treatment at eMedicine *^ a b c "Synthroid (Levothyroxine Sodium) Drug Information: Uses, Side Effects, Drug ... Acute overdose may cause fever, hypoglycemia, heart failure, coma, and unrecognized adrenal insufficiency. ... Levothyroxine is typically used to treat hypothyroidism,[9] and is the treatment of choice for people with hypothyroidism,[10] ... Massive overdose can be associated with increased sympathetic activity and thus require treatment with beta-blockers.[18] ...
listen)) is the science and practice of the diagnosis, treatment, and prevention of disease.[4][5] The word "medicine" is ... deals with pain and symptom relief and emotional support in patients with terminal illnesses including cancer and heart failure ... Addiction medicine deals with the treatment of addiction.. *Medical ethics deals with ethical and moral principles that apply ... The diagnosis and treatment may take only a few minutes or a few weeks depending upon the complexity of the issue. ...
Usually the treatment is done in the second trimester of pregnancy, for a woman who had either one or more late miscarriages in ... injury to the cervix or bladder bleeding Cervical Dystocia with failure to dilate requiring Cesarean Section displacement of ... The treatment consists of a strong suture being inserted into and around the cervix early in the pregnancy, usually between ... Cervical cerclage, also known as a cervical stitch, is a treatment for cervical incompetence or insufficiency, when the cervix ...
The treatment effect (difference between treatments) was quantified using the Hodges-Lehmann (HL) estimator, which is ... Treatment A decreased weight by HLΔ = 5 kg (0.95 CL [2, 9] kg, 2P = 0.02, ρ = 0.58).". However it would be rare to find so ... "Outcomes of the two treatments were compared using the Wilcoxon-Mann-Whitney two-sample rank-sum test. ... weight for subjects on treatment A and B respectively are 147 [121, 177] and 151 [130, 180] kg. ...
Treatment[edit]. The decision to treat is based on a belief that the child will be disabled by being extremely short as an ... The cost of treatment depends on the amount of growth hormone given, which in turn depends on the child's weight and age. One ... Treatment is expensive and requires many years of injections with human growth hormones. The result depends on the cause, but ... For example, several years of successful treatment in a girl who is predicted to be 146 centimetres (4 ft 9 in) as an adult may ...
It has received regulatory approval for use as a treatment for non-small cell lung cancer,[6][4][7][8] although there is ... May 2012). "Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of ... "Breast Cancer Research and Treatment. 133 (3): 1057-65. doi:10.1007/s10549-012-2003-y. PMC 3387495. PMID 22418700.. ... "Breast Cancer Research and Treatment. 134 (3): 1149-59. doi:10.1007/s10549-012-2126-1. PMC 3409367. PMID 22763464.. ...
Treatment failure, i.e. persistence of original or appearance of new signs of the disease, occurs only in a few people.[171] ... Treatment[edit]. Antibiotics are the primary treatment.[2][23] The specific approach to their use is dependent on the ... Facial palsy may resolve without treatment; however, antibiotic treatment is recommended to stop other Lyme complications.[30] ... In case of failure, guidelines recommend retreatment with injectable ceftriaxone.[113] Several months after treatment for Lyme ...
By 1556 Georgius Agricola's treatment of mining and smelting of ore, De Re Metallica, included a detailed description of ... "The Failure of the Munich Experiments". Skeptical Inquirer. CSICOP. Retrieved 2006-11-14. The researchers themselves concluded ...
There is currently no form of treatment, and such declines have been described as "unprecedented" in bat evolutionary history ... "From COVID-19 to massive wildfires, floods, melting glaciers and unprecedented heat, our failure to meet the Aichi ( ... It was called a global failure by Inger Andersen, head of the United Nations Environment Programme: " ...
diagnosis, prevention, monitoring, treatment or alleviation of disease,. *diagnosis, monitoring, treatment, alleviation of or ... Failure to meet cost targets will lead to substantial losses for an organisation. In addition, with global competition, the R&D ... Treatment equipment includes infusion pumps, medical lasers and LASIK surgical machines.. *Life support equipment is used to ... Medical equipment (also known as armamentarium[77]) is designed to aid in the diagnosis, monitoring or treatment of medical ...
In New York City, Xing is killed by his boss for his failure to get Scylla. Mahone instructs Glenn to help him find his son's ... Krantz gives orders for Michael to be given a medical treatment that could kill him, but which will certainly damage his mind; ... She has Oren killed for the failure, making Krantz suspect her. The other three attack the church and find guns and special ... Christina loses the deal with Banarjee because of failure to deliver Scylla. Mahone apparently betrays Michael and calls ...
Please see Suspected Cephalosporin Treatment Failure in Gonococcal Infections Among Adolescents and Adults - STI Treatment ...
Technological breakthroughs are changing the course of heart-failure treatment -- but doubts remain about how many people will ... Heart-Failure Treatment by Device. Technological breakthroughs are changing the course of heart-failure treatment -- but doubts ... the biggest obstacle to the widespread use of devices in heart-failure treatment is its costs. Drug treatment is definitely ... But the last few years have witnessed a surge in both the types of devices being tested for heart-failure treatment, and in the ...
WebMD looks at how this medication is used to treat heart failure. ... There are several types of beta-blockers, but only three are approved by the FDA to treat heart failure:. * Bisoprolol (Zebeta) ... Drugs called beta-blockers perform four main tasks essential for people with heart failure:. *Improve your hearts ability to ... If you have heart failure, you need beta-blockers -- even if you do not have symptoms. Beta-blockers are prescribed for ...
Researchers in Britain are hopeful for another new treatment possibility for heart failure using the patients stem cell. ...
Over five million Americans suffer annually from heart failure, yet the medication most often prescribed may not be the most ... Bikdelis report is an indication of the lack of proper "head-to-head studies" of different heart failure treatments, said ... Heart failure is typically treated by loop diuretics, commonly known as water pills, which stimulate the kidneys to excrete ... The widespread use of furosemide is based on habit rather than on scientific evidence that it is the more beneficial treatment ...
Technological breakthroughs are changing the course of heart-failure treatment -- but doubts remain about how many people will ... Technological breakthroughs are changing the course of heart-failure treatment -- but doubts remain about how many people will ... the biggest obstacle to the widespread use of devices in heart-failure treatment is its costs. Drug treatment is definitely ... An ICD is used for heart-failure treatment when the person is considered to be a high risk of dying from an abnormal heart ...
... reduce the number of patients who are readmitted to hospitals within 30 days of being discharged for congestive heart failure ...
Editorial: Treatment of liver failure.. Br Med J 1973; 4 doi: https://doi.org/10.1136/bmj.4.5885.126 (Published 20 October 1973 ...
Theres a form of heart failure that may be more common than thought. And theres no treatment for it. ... Existing Drug Shows Promise in Treating Heart Failure. Written by Matt Berger. on September 6, 2018 ... Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information. ...
Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to ... In patients with high cholesterol levels, aspirin in in normal doses has hardly any anti-clotting effects, whereas treatment ...
Learn about the treatments of kidney failure in cats here. ... Chronic kidney failure is very dangerous for cats, but if ... treated it does tend to offer better survival rates than acute kidney failure. ... Treatment and Prognosis for Kidney Failure in Cats. Chronic kidney failure is very dangerous for cats, but if treated it does ... an option unlikely with chronic kidney failure. Emergency veterinary treatment of acute kidney failure can include:. * ...
Major gaps remain in use and appropriate dosing of guideline-recommended medications for heart failure with reduced ejection ... Cite this: CHAMP-HF: Heart Failure Treatment in US Remains Subpar - Medscape - Jul 17, 2018. ... There is substantial opportunity to improve care and outcomes for patients with heart failure with reduced ejection fraction. ... the Heart Failure Society of America/Emergency Medicine Foundation Acute Heart Failure Young Investigator award funded by ...
Some people have symptoms of kidney failure and some do not. Causes of acute and chronic kidney failure include medications, ... Kidney failure can be either acute (comes on suddenly) or chronic (it develops over a long period of time). ... Kidney failure occurs when the kidneys no longer function well enough to do their job. ... What is the treatment for kidney failure?. Prevention is always the goal with kidney failure. Chronic diseases such as ...
Treatments can help you live longer and can even strengthen the heart in some cases. ... Heart failure is a chronic disease that needs lifelong management. ... Treatment. Heart failure is a chronic disease needing lifelong management. However, with treatment, signs and symptoms of heart ... To determine the most appropriate treatment for your condition, doctors may classify heart failure using two systems:. * New ...
Congestive heart failure (CHF) is a chronic condition that affects the chambers of your heart. Learn more about CHF, including ... Treatment can be complicated. Talk with your doctor about what heart failure at this stage may mean for you. ... Symptoms of heart failure in children and infants. It can be difficult to recognize heart failure in infants and young children ... Heart Failure. Heart failure is characterized by the hearts inability to pump an adequate supply of blood. Learn about heart ...
The American Heart Association explains what can be done to treat heart failure whether by medication, lifestyle changes or ... What is Heart Failure? , Spanish. How Can I Live with Heart Failure? , Spanish. Ejection Fraction Explained , Spanish. ... Heart failure caused by damage to the heart that has developed over time cant be cured. But it can be treated, quite often ... In the first of a four-part series on heart failure, we investigate what it is, what causes it and whats the prognosis.. The ...
What are the treatment options for advanced heart failure?. Heart failure is a progressive condition that deteriorates over ... Although heart failure is a serious condition, there are treatment options available to restore patient health. ... In patients with advanced heart failure, these medications and treatments ultimately become insufficient and doctors may ... One option for treating advanced heart failure is the implantation of a Ventricular Assist Device, or VAD. But what is a VAD ...
Noncompliance and treatment failure in children with asthma.. Milgrom H1, Bender B, Ackerson L, Bowry P, Smith B, Rand C. ... about childrens use of inhaled medications is needed because of the growing reliance on these drugs in the treatment of asthma ...
Andrew Clark, from the British Society for Heart Failure and the University of Hull, told BBC News. "How to interpret that for ... Less costly aspirin is as effective for heart failure patients with normal heart rhythm as other more expensive drugs, such as ... But the WARCEF study was instrumental in concluding that aspirin was clearly a better a choice for heart failure patients with ... The equality in effectiveness is dependent, however, on the fact that patients who suffer from heart failure also have a normal ...
Operative Treatment of Cardiac Failure in Early Infancy Br Med J 1957; 2 :645 ... Operative Treatment of Cardiac Failure in Early Infancy. Br Med J 1957; 2 doi: https://doi.org/10.1136/bmj.2.5045.645 ( ...
Background Persistent or recurrent hyperthyroidism after treatment with radioactive iodine (RAI) is common and many patiedlxnts ... and methimazole treatment (HR 2.55; 95 % CI 1.22-5.33; p = 0.01) were associated with failure. ... Total thyroidectomy: a safe and effective treatment for Graves disease. J Surg Res. 2011;168(1):1-4.PubMedCentralPubMed ... Late results of surgical treatment. Eur J Endocrinol. 1996;134(6):710-15.PubMedCrossRefGoogle Scholar ...
RFE/RL journalists report the news in 27 languages in 23 countries where a free press is banned by the government or not fully established. We provide what many people cannot get locally: uncensored news, responsible discussion, and open debate.
... heart failure is the third most common cause of death in Germany and constitutes the most common cause for inpatient admission ... Improving Treatment Adherence in Heart Failure. A systematic review and meta-analysis of pharmacological and lifestyle ... In spite of improved treatment options, heart failure is the third most common cause of death in Germany and constitutes the ... Background: Despite improved treatment options, heart failure remains the third most common cause of death in Germany and the ...
... treatments include estrogen therapy for menopause symptoms and IVF with donor eggs for women who want to become pregnant. ... Treatment. Treatment for premature ovarian failure usually focuses on the problems that arise from estrogen deficiency. Your ... Theres no treatment proved to restore this common complication of premature ovarian failure. Its important to understand and ... Learning that you have premature ovarian failure may be emotionally difficult. But with proper treatment and self-care, you can ...
Learn more about advances in treatment for congestive heart failure (CHF), which include various medicines, implantable devices ... and Heart Failure Society of America maintain treatment guidelines for all types of heart failure. In 2017, the guidelines were ... Treatment Advances for Patients With Heart Failure. Nicole Van Hoey, PharmD , June 28, 2017 ... In addition to lifestyle changes, treatments to minimize symptoms of heart failure can increase quality of life and reduce the ...
Study: Heart Failure Treatment May Change. Study: Heart Failure Treatment May Change ... It has developed a procedure to combat heart failure using adult stem cells. ...
Acute decompensated heart failure (ADHF) is a common and potentially fatal cause of acute respiratory distress. The clinical ... Treatment and prognosis of heart failure with preserved ejection fraction. *Treatment of acute decompensated heart failure in ... See Treatment of acute decompensated heart failure in acute coronary syndromes and Prognosis and treatment of cardiogenic ... Treatment of acute decompensated heart failure: Components of therapy. *Treatment of bilateral atherosclerotic renal artery ...
Chiron CHIR was down sharply in the premarket Wednesday after its development treatment for sepsis was found to be ineffective ... Chiron Down Sharply on Sepsis Treatment Failure. Author:. TSC Staff. Publish date:. Nov 21, 2001 8:54 AM EST. ... was down sharply in the premarket Wednesday after its development treatment for sepsis was found to be ineffective in a trial. ...
Learn about the symptoms, treatment, and how to prevent this potentially fatal condition. ... In congestive heart failure, the heart no longer works properly. ... Some common treatments for heart failure include:. Medications ... Treatments. Damage to the hearts pumping action caused by heart failure cannot be repaired. Nevertheless, current treatments ... Left-sided heart failure. Left-sided heart failure is the most common form of congestive heart failure. The left side of the ...
There are different types of heart failure, but they all result from conditions that weaken the heart muscles. There is no cure ... Congestive heart failure means that the heart is unable to pump blood around the body properly. ... Treatments. Damage to the hearts pumping action caused by heart failure cannot be repaired. Nevertheless, current treatments ... Left-sided heart failure. Left-sided heart failure is the most common form of congestive heart failure. The left side of the ...
  • Chronic kidney failure is very dangerous for cats, but if treated it does tend to offer better survival rates than acute kidney failure. (petfinder.com)
  • On the other hand, if acute kidney failure is addressed immediately and successfully, a cat may be able to regain full functioning of his kidneys - an option unlikely with chronic kidney failure. (petfinder.com)
  • Acute Renal (Kidney) Failure in Cats. (petfinder.com)
  • Kidney failure may occur from an acute situation that injures the kidneys or from chronic diseases that gradually cause the kidneys to stop functioning. (rxlist.com)
  • In acute renal failure , kidney function is lost rapidly and can occur from a variety of insults to the body. (rxlist.com)
  • Acute decompensated heart failure (ADHF) is a common and potentially fatal cause of acute respiratory distress. (uptodate.com)
  • See 'Treatment of acute decompensated heart failure: Components of therapy' and 'Evaluation of acute decompensated heart failure' . (uptodate.com)
  • Treatment of ADHF and cardiogenic shock in the setting of acute coronary syndrome are discussed separately. (uptodate.com)
  • See 'Treatment of acute decompensated heart failure in acute coronary syndromes' and 'Prognosis and treatment of cardiogenic shock complicating acute myocardial infarction' and 'Right ventricular myocardial infarction' . (uptodate.com)
  • TUESDAY, Feb. 19 (HealthDay News) -- Studies show no particular advantage to any single treatment for acute renal failure, the sudden collapse of kidney function that carries with it a high risk of death, Canadian researchers report. (go.com)
  • The incidence of acute kidney failure appears to be increasing, the report said, although exact numbers are lacking. (go.com)
  • The outlook is much grimmer in many cases of acute kidney failure because of the medical problems that led the kidneys to suddenly stop working, Swartz said. (go.com)
  • The two main forms are acute kidney injury, which is often reversible with adequate treatment, and chronic kidney disease, which is often not reversible. (disabled-world.com)
  • Renal failure is divided into Chronic Renal Failure and Acute Renal Failure. (disabled-world.com)
  • Acute renal failure means a person's kidneys suddenly lose their ability to filter waste products from their blood. (disabled-world.com)
  • Acute renal failure might be a reversible condition. (disabled-world.com)
  • A person has an increased chance of experiencing acute renal failure if they have heart failure, obesity, long-term diabetes, or high blood pressure. (disabled-world.com)
  • Other things that raise the risk of acute renal failure include being ill and already in the hospital, a belly or heart surgery, a bone marrow transplant, or if the affected person is a Senior. (disabled-world.com)
  • Chronic Renal Failure: Compared to acute renal failure, chronic renal failure means a person's kidneys no longer have the ability to work as they should as the condition becomes increasingly worse. (disabled-world.com)
  • Organic FTT refers to growth failure that is due to an acute or chronic medical condition that interferes with normal food intake, absorption or digestion of food, or is due to increased calorie need to keep up or help growth. (nationwidechildrens.org)
  • When is surgical intervention indicated for the treatment of acute liver failure (ALF)? (medscape.com)
  • Liver transplantation is the definitive treatment for acute liver failure. (medscape.com)
  • AASLD position paper: the management of acute liver failure: update 2011. (medscape.com)
  • Lee WM, Stravitz RT, Larson AM. Introduction to the revised American Association for the Study of Liver Diseases position paper on acute liver failure 2011. (medscape.com)
  • Intensive care of patients with acute liver failure: recommendations of the U.S. Acute Liver Failure Study Group. (medscape.com)
  • Jalan R. Acute liver failure: current management and future prospects. (medscape.com)
  • Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure. (medscape.com)
  • Jalan R, Olde Damink SW, Deutz NE, Hayes PC, Lee A. Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension. (medscape.com)
  • Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure. (medscape.com)
  • Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. (medscape.com)
  • Measurement of serum acetaminophen-protein adducts in patients with acute liver failure. (medscape.com)
  • Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure. (medscape.com)
  • Acute kidney failure (also referred to as renal failure) can happen rapidly. (emedicinehealth.com)
  • Acute kidney failure occurs in a few people who are hospitalized for any reason. (emedicinehealth.com)
  • Prerenal failure is the most common type of acute renal failure (60% to 70% of all cases). (emedicinehealth.com)
  • It is the rarest cause of acute kidney failure (5% to 10% of all cases). (emedicinehealth.com)
  • Martin Cowie drew attention to the increasing burden on the National Health Service: heart failure now accounts for 5% of all acute medical admissions in the UK and 10% of bed days. (bmj.com)
  • Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure. (nih.gov)
  • To determine the short-term cost-utility of molecular adsorbent recirculating system (MARS) treatment in acute liver failure (ALF). (nih.gov)
  • The cost-effectiveness acceptability curve for MARS vs standard medical therapy in the historical control group in acute liver failure. (nih.gov)
  • ALF: Acute liver failure. (nih.gov)
  • Acute renal failure has been reported with use of Cosmegen. (thebody.com)
  • Unlike acute renal failure, which happens quickly and suddenly, chronic renal failure happens gradually - over a period of weeks, months, or years - as the kidneys slowly stop working, leading to end-stage renal disease (ESRD). (medbroadcast.com)
  • In a new report published in The American Journal of Medicine , researchers analyzed over five million hospitalizations for acute heart failure, which provided much needed insights. (elsevier.com)
  • HFpEF is, in fact, common among patients hospitalized with acute heart failure. (elsevier.com)
  • Recently, a third form of liver failure known as acute-on-chronic liver failure (ACLF) is increasingly being recognized. (wikipedia.org)
  • The diagnosis of acute liver failure is based on physical exam, laboratory findings, patient history, and past medical history to establish mental status changes, coagulopathy, rapidity of onset, and absence of known prior liver disease respectively. (wikipedia.org)
  • One scheme defines "acute hepatic failure" as the development of encephalopathy within 26 weeks of the onset of any hepatic symptoms. (wikipedia.org)
  • Acute on chronic liver failure" is said to exist when someone with chronic liver disease develops features of liver failure. (wikipedia.org)
  • EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure" (PDF). (wikipedia.org)
  • Major gaps remain in use and dosing of evidence-based, guideline-recommended medications for heart failure with reduced ejection fraction (HFrEF), according to a new analysis of data from the Change the Management of Patients with Heart Failure (CHAMP-HF) registry. (medscape.com)
  • There is substantial opportunity to improve care and outcomes for patients with heart failure with reduced ejection fraction. (medscape.com)
  • An echocardiogram measures your ejection fraction, an important measurement of how well your heart is pumping, and which is used to help classify heart failure and guide treatment. (mayoclinic.org)
  • The severity of heart failure is graded by New York Heart Association classes according to symptoms and a measure of the heart muscle's ability to pump blood (ejection fraction). (healthcentral.com)
  • 2 Although it is important for nurses to have knowledge of these 7 key indicators and the rational behind the medical treatment of this population set, this article focuses on the pharmacological treatments used for symptoms of HF and reduced left ventricular ejection fraction (LVEF). (nursingcenter.com)
  • Kurrelmeyer KM, Ashton Y, Xu J, Nagueh SF, Torre-Amione G, Deswal A. Effects of spironolactone treatment in elderly women with heart failure and preserved left ventricular ejection fraction. (clinicaltrials.gov)
  • Results showed that carvedilol treatment alone yielded a mean increase in ejection fraction units in both groups of patients, 22 percent and 15 percent, respectively. (innovations-report.com)
  • In diastolic heart failure, the ejection fraction is normal or increased. (emedicinehealth.com)
  • Women with systolic heart failure pump a less-than-normal amount of blood out of the heart with each heartbeat (they have a reduced ejection fraction). (simstat.com)
  • Patients with classic symptomatic chronic heart failure - depressed left ventricular (LV) systolic function (Left Ventricular Ejection Fraction (LVEF) (eurekalert.org)
  • Heart failure with preserved ejection fraction (HFpEF) has been particularly difficult to treat, or even describe, with definitions and terminology still under debate within the medical community. (elsevier.com)
  • The number of patients hospitalized with HFpEF is now comparable to those with traditional heart failure with a reduced ejection fraction (HFrEF) and is projected to exceed that of HFrEF within the next few years. (elsevier.com)
  • Medical care for chronic kidney failure is usually aimed at controlling symptoms and preventing the condition from worsening, usually by treating anemia, controlling vomiting and targeting specific electrolyte imbalances. (petfinder.com)
  • Chronic kidney failure results when a disease slowly destroys the kidneys. (emedicinehealth.com)
  • Chronic Kidney (Renal) Failure in Cats. (petfinder.com)
  • Methods used in the various trials were continuous renal replacement therapy (CRRT), in which the person whose kidneys have failed gets continuous dialysis, a machine treatment that removes impurities from the blood, and intermittent hemodialysis, in which the purifying treatment is not continuous. (go.com)
  • Information regarding the basics of renal failure, a condition when the kidneys lose the ability to filter waste products from the blood. (disabled-world.com)
  • What is Renal Failure? (disabled-world.com)
  • Renal failure, also known as kidney failure or renal insufficiency, is defined as a medical condition in which the kidneys fail to adequately filter waste products from the blood. (disabled-world.com)
  • The information below concerns the basics of renal failure. (disabled-world.com)
  • Chronic renal failure is hard to reverse because much of the person's kidney function has been lost. (disabled-world.com)
  • Most people with renal failure opt for dialysis treatment, or a kidney transplant. (disabled-world.com)
  • If a person is already in the hospital, testing done for other issues might find renal failure. (disabled-world.com)
  • If the person is not in the hospital, yet experiences symptoms of renal failure, a doctor will ask about their symptoms, the tests that have been performed, as well as the medications the person takes. (disabled-world.com)
  • A diagnosis of chronic renal failure is confirmed through blood testing that measures the buildup of waste products in the person's blood. (disabled-world.com)
  • Additional tests are used to achieve a diagnosis of the type of renal failure. (disabled-world.com)
  • Once kidney function diminishes to less than 10 to 15% and end-stage renal disease (ESRD) occurs, dialysis or transplant are the only treatment options. (dlife.com)
  • Glycemic control reduces the risk of blindness, renal failure, neuropathy, and other microvascular complications in type 2 diabetes ( 1 - 3 ). (diabetesjournals.org)
  • An extended lifespan provides more time to develop blindness, renal failure, and other microvascular complications. (diabetesjournals.org)
  • Postrenal failure is sometimes referred to as obstructive renal failure, since it is often caused by something blocking elimination of urine produced by the kidneys. (emedicinehealth.com)
  • Furthermore, once diagnosed, heart failure is inadequately managed, as many general practitioners fear that angiotensin converting enzyme inhibitors will cause adverse effects such as hypotension and renal failure. (bmj.com)
  • Chronic renal failure, or chronic kidney disease (CKD), is a slow and progressive decline of kidney function. (medbroadcast.com)
  • Chronic renal failure can be present for many years before you notice any symptoms. (medbroadcast.com)
  • If your doctor suspects that you may be likely to develop renal failure, they will probably catch it early by conducting regular blood and urine tests. (medbroadcast.com)
  • Some signs of chronic renal failure are more obvious than others. (medbroadcast.com)
  • Being diagnosed with chronic renal failure can be very frightening. (medbroadcast.com)
  • HFpEF is characterized by a "stiff ventricle" and patients typically have other medical conditions including hypertension, diabetes, lung disease, and/or chronic renal failure. (elsevier.com)
  • An ICD is used for heart-failure treatment when the person is considered to be a high risk of dying from an abnormal heart rhythm -- called sudden cardiac death. (webmd.com)
  • ICDs can be implanted alone, but they are also combined with other devices, such as cardiac resynchronization therapy, for heart failure treatment. (webmd.com)
  • Cardiac resynchronization therapy is a new and promising treatment. (webmd.com)
  • This finding should give patients reassurance when discussing their medication with their heart failure specialist, and more freedom to choose the treatment which works best for them," said Ellen Mason, a senior cardiac nurse at the foundation. (redorbit.com)
  • they appear to reduce CHF symptoms and cardiac death better than standard treatments (e.g. (healthcentral.com)
  • Lysyl oxidase-like 2 enzyme, is identified as the molecule that produces fibrosis of the cardiac muscle which stimulates heart failure. (medindia.net)
  • Author name, Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment, Nature Communications (2017) Doi: 10.1038/ncomms13710. (medindia.net)
  • The definition of heart failure encompasses a broad range of conditions each with a compromised cardiac function," researchers write in the study, which is published in PLOS Computational Biology . (upi.com)
  • This book is a timely and useful contribution to the overall knowledge of the management of the heart failure patient and provides a useful and worthwhile read for every cardiac surgeon of the day. (springer.com)
  • It may also provide relief from the symptoms of Class III and ambulatory Class IV heart failure and improve quality of life and cardiac function. (cnbc.com)
  • The progression to heart failure largely is due to the extent of cardiac fibrosis, but also involves the duration of inflammation. (news-medical.net)
  • Dr. Garvin's studies will evaluate fibroblasts in the heart and in isolation to determine how ACE inhibitor treatment impacts inflammatory and fibrotic signaling -- and ultimately cardiac healing -- after a heart attack. (news-medical.net)
  • Identifying whether cardiac fibroblasts contribute to the extent of pro-inflammatory signaling, in addition to fibrosis, may increase the ways in which we can intervene pharmacologically to reduce the incidence of heart failure and produce a healthier population of individuals recovering from a cardiac event. (news-medical.net)
  • Many positive effects of ACE inhibitor treatment on cardiac injury are due to treatment during and/or after the cardiac insult. (news-medical.net)
  • Our goal is not to use this approach as a treatment, but rather a tool to understand cardiac fibroblasts. (news-medical.net)
  • We have shown that this transient treatment leads to persistent changes in cardiac fibroblast physiology that improves inflammatory and fibrotic responses to injury. (news-medical.net)
  • Levothyroxine treatment started either before or after the diagnosis of heart failure was associated with an increased risk of death, both overall and due to heart problems, and major adverse cardiac events. (thyroid.org)
  • This treatment, known as cardiac resynchronisation therapy (CRT), can help the heart pump blood more effectively. (bhf.org.uk)
  • SCIPIO was the first in-human trial to assess whether cardiac stem cells (CSCs) can restore heart function in patients suffering from post-myocardial-infarction heart failure. (medgadget.com)
  • Of note, no adverse effects were reported, confirming the excellent safety of cardiac cell treatment. (medgadget.com)
  • Previously, many cancer patients endured the invasive insertion of cardiac devices or full heart transplants in an effort to treat heart failure resulting from chemotherapy treatment. (innovations-report.com)
  • Fourteen of the 15 patients achieved significant recovery of cardiac function and improvement in NYHA functional class following treatment and 13 patients were successfully discharged on a regimen of ACE inhibitors in combination with carvedilol. (innovations-report.com)
  • Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. (eurekalert.org)
  • The treatment works, he said, by increasing the number of cardiac muscle cells and blood capillaries in the tissue around damaged areas of the heart. (montrealgazette.com)
  • The treatment being developed by the heart institute team restored heart function in mice with scarred cardiac muscle. (montrealgazette.com)
  • 2. The method of claim 1 wherein the heart failure is selected from the group consisting of congestive heart failure, diastolic heart failure, low-output heart failure, right-sided heart failure, cardiac hypertrophy, and cardiac fibrosis. (google.es)
  • Heart failure, which is generally characterised by impaired cardiac function and exercise intolerance affects a very large number of people worldwide, particularly in the Western world. (google.es)
  • Tako-Tsubo syndrome as a rare cause of cardiac failure in liver transplantation," Liver International , vol. 30, no. 1, pp. 159-160, 2010. (hindawi.com)
  • Diastolic failure , or diastolic dysfunction, happens when the muscle in the left ventricle becomes stiff. (healthline.com)
  • He believed that the headline data on epidemiology were already available, a view challenged by Martin Cowie (London), particularly in respect of diastolic heart failure. (bmj.com)
  • The purpose of the study is to collect information about the potential benefit and safety of low dose spironolactone for a patient with diastolic heart failure (DHF) and to determine whether spironolactone can cause the patient's condition to improve. (clinicaltrials.gov)
  • Subjects with diastolic heart failure defined based on clinical symptoms, echocardiography diastology parameters and brain natriuretic peptide level will be randomized in a 1:1 fashion to either placebo or spironolactone 25mg daily for 6 months. (clinicaltrials.gov)
  • There are two types of heart failure, systolic and diastolic. (emedicinehealth.com)
  • Diastolic heart failure is more common in patients older than 75 years of age, especially in patients with high blood pressure , and it is also more common in women. (emedicinehealth.com)
  • Many people have both systolic and diastolic heart failure. (medbroadcast.com)
  • The Advanced Heart Failure Center at UPMC's Heart and Vascular Institute specializes in the treatment of people with congestive heart failure (CHF). (upmc.com)
  • Advances in research are providing more options and improving outcomes for people with congestive heart failure. (emedicinehealth.com)
  • People with congestive heart failure sometimes do not suspect a problem with their heart or have symptoms that may not obviously be from the heart. (emedicinehealth.com)
  • The VAD provides relief from the symptoms of heart failure, helping patients to feel stronger and return to a more active lifestyle. (medtronic.com)
  • The most common symptoms of heart failure are increasing tiredness, shortness of breath, and swelling in the stomach or ankles. (healthcentral.com)
  • In addition to lifestyle changes, treatments to minimize symptoms of heart failure can increase quality of life and reduce the risk of death. (healthcentral.com)
  • Symptoms of heart failure may include irregular and rapid heartbeats. (medicalnewstoday.com)
  • Novartis' twice-a-day pill, still known by its code name LCZ696, reduced deaths, hospitalizations, and disabling symptoms of heart failure. (heraldnet.com)
  • They help relieve the symptoms of heart failure, including leg swelling and shortness of breath, improving your ability to perform daily tasks and minimizing the time spent in the hospital. (simstat.com)
  • Researchers, led by clinical principal investigator Shunichi Homma, MD, of Columbia University Medical Center in New York and statistical principal investigator John L.P. (Seamus) Thompson, PhD, of Columbia University´s Mailman School of Public Health, found that aspirin and warfarin are equally effective in preventing strokes in people with heart failure. (redorbit.com)
  • American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. (springer.com)
  • The goal of this systematic review is to study the efficacy of adherence-promoting interventions for patients with heart failure with respect to the taking of medications, the implementation of recommended lifestyle changes, and the improvement in clinical endpoints. (aerzteblatt.de)
  • This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. (springer.com)
  • The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. (springer.com)
  • When we then looked in the patients' medical records, we saw that those with FOXM1 present in the nucleus of their cancer cells had worse treatment outcomes, higher rates of chemotherapy resistance and lower survival rates compared to patients without FOXM1 present in the nucleus,' said Dr. Irum Khan, assistant professor of clinical medicine in the UIC College of Medicine and first author on the paper. (news-medical.net)
  • Drugs that suppress FOXM1 in combination with the standard treatment, such as ixazomib, should result in better outcomes, but clinical trials will ultimately be needed to prove this theory. (news-medical.net)
  • The pivotal study, begun in 2009, enrolled 8,400 patients with mild to moderately severe heart failure at more than 1,000 centers around the world, making it the largest clinical trial in heart failure ever undertaken. (heraldnet.com)
  • Part of this effort utilizes evidence-based practices and the guidelines for the care of patients with CHF in conjunction with the American College of Cardiology (ACC) and the AHA 2005 Clinical Performance Measures for Adults with Chronic Heart Failure. (nursingcenter.com)
  • HF is currently defined as a clinical syndrome characterized by symptoms of pump failure secondary to structural and functional disorders that impairs the ability of the ventricle to fill or eject blood. (nursingcenter.com)
  • Hemodialysis treatment is typically administered three times a week and takes three to four hours (depending on the patient's clinical needs and the type of dialyzer used). (dlife.com)
  • Treatment failure can be categorized as virologic failure, immunologic failure, clinical failure, or some combination of the three. (nih.gov)
  • Clinical failure is defined as the occurrence of new opportunistic infections and/or other clinical evidence of HIV disease progression during therapy. (nih.gov)
  • He defined prevention as either delaying the development of clinical heart failure or preventing its occurrence completely. (bmj.com)
  • They will be assessed over this 6 month period for improvement in exercise capacity, clinical symptoms, echocardiography diastology parameters, and biomarkers specific for heart failure. (clinicaltrials.gov)
  • The San Francisco Department of Public Health (SFDPH) is investigating several clinical failures in syphilis patients treated with the macrolide antibiotic azithromycin. (cdc.gov)
  • Community patients with heart failure (HF) are older, less often treated by HF specialists, and have more comorbidity than those in randomized clinical trials. (nih.gov)
  • The experts attending the most recent symposium presented novel basic science and clinical research approaches that strive to reach a common goal - to improve treatment of, and ultimately to rapidly identify and prevent, the congenital cardiovascular defects and the subsequent damage acquired after birth that ultimately results in heart failure. (scienceblog.com)
  • It is the goal of the Riley Heart Center Symposia to establish strong communication between the basic and clinical research communities and ultimately establish collaborative projects to prevent the onset of congenital defects as well as heart failure in the young. (scienceblog.com)
  • The clinical characteristics of those patients in whom aspirin treatment failed were compared with three control groups, each comprising 129 patients who had had only a single ischemic stroke and were then taking aspirin. (ahajournals.org)
  • Hyperlipidemia and ischemic heart disease are risk factors for stroke recurrence despite aspirin treatment, which requires further clinical and laboratory evaluation. (ahajournals.org)
  • Be aware that this type of kidney failure usually requires lifetime of monitoring and special care. (petfinder.com)
  • Kidney Failure (Uremia) Symptoms in Cats. (petfinder.com)
  • Kidney Failure in Cats. (petfinder.com)
  • Learn about kidney failure in cats and the best way to spot symptoms. (petfinder.com)
  • Symptoms of kidney failure are due to the build-up of waste products and excess fluid in the body that may cause weakness , shortness of breath , lethargy, swelling, and confusion . (rxlist.com)
  • Initially kidney failure may cause no symptoms. (rxlist.com)
  • Unfortunately, kidney failure may be progressive in other situations and may be irreversible. (rxlist.com)
  • The diagnosis of kidney failure usually is made by blood tests measuring BUN, creatinine , and glomerular filtration rate (GFR). (rxlist.com)
  • Treatment of the underlying cause of kidney failure may return kidney function to normal. (rxlist.com)
  • Lifelong efforts to control blood pressure and diabetes may be the best way to prevent chronic kidney disease and its progression to kidney failure. (rxlist.com)
  • Since most people have two kidneys, both kidneys must be damaged for complete kidney failure to occur. (rxlist.com)
  • What are the Ayurvedic Treatment For kidney Failure for patients. (answerbag.com)
  • Diabetes is the most common cause of kidney failure in the U.S. (dlife.com)
  • In this article, we will explore and better understand treatment options for kidney failure. (dlife.com)
  • But these biomarker levels can also be affected by obesity, age, kidney disease, severe infection, high blood pressure, abnormal heart rhythms and specific heart failure medication," says Dr. Adedinsewo. (dailypress.com)
  • Kidney failure occurs when the kidneys partly or completely lose their ability to filter water and waste from the blood. (emedicinehealth.com)
  • Destruction occurs over many years, usually with no symptoms until the late stage of kidney failure. (emedicinehealth.com)
  • The study also shows that kidney function can be restored in mice with cancer through treatment, using an inhibitor to target the enzyme peptidyl arginine deiminase 4 (PAD4) - an enzyme required for neutrophils to form NETs. (uu.se)
  • We believe that these findings can lead to novel treatment options to prevent kidney damage and improve survival rates in cancer patients," says Jessica Cedervall, researcher at the Department of Medical Biochemistry and Microbiology at Uppsala University. (uu.se)
  • 'Kidney Failure Treatment Options - Vietnamese' is our popular booklet designed to provide you with information about the different types of treatment for kidney disease, translated into Vietnamese. (kidney.org.au)
  • After 3 weeks of treatment, her kidney results came in and treatment was discontinued. (thebody.com)
  • Some of the symptoms - such as fatigue - may have been present for some time, but can come on so gradually that they aren't noticed or attributed to kidney failure. (medbroadcast.com)
  • As the kidney failure gets worse and the toxins continue to build up in the body, seizures and mental confusion can result. (medbroadcast.com)
  • The future of the condition, however, depends on the medical problem that caused the kidney failure, how much kidney damage has occurred, and what, if any, complications are present. (medbroadcast.com)
  • Your medical history is important in determining your risk factors for developing kidney failure. (medbroadcast.com)
  • When you have kidney failure , it means your kidneys are damaged. (kidney.org)
  • When it comes time to choose a treatment for kidney failure, the decision may often be stressful. (kidney.org)
  • However, a kidney transplant is a treatment, not a cure, and it is important to care for the new kidney with the same care as before receiving the transplant. (kidney.org)
  • For the full PDF brochure, Choosing a Treatment for Kidney Failure click here . (kidney.org)
  • Transform the future of kidney disease research, diagnosis and treatment with your special gift before March 31st. (kidney.org)
  • We are now confronted with large numbers of terminally ill patients for whom conventional therapies for heart failure have been exhausted and for whom repeated hospital visits are necessary. (springer.com)
  • Current therapies for the treatment of HF are aimed at regression and prevention of left ventricular dysfunction. (nursingcenter.com)
  • Alarcon said his team believes it performs better than any of the cell-based therapies or drug treatments currently available. (montrealgazette.com)
  • When you start taking beta-blockers, your heart failure symptoms may become a bit worse while your heart adjusts to the medication. (webmd.com)
  • In the early stages of heart failure, medication and lifestyle changes can help to alleviate symptoms. (medtronic.com)
  • This disease burden has remained unchanged at this high level for patients and the healthcare system in spite of falling cardiovascular death rates ( 2 5 ) and the successful development of medication treatments. (aerzteblatt.de)
  • Is it possible to support patients with heart failure and to improve their adherence to medication therapy and lifestyle modifications in a sustained fashion? (aerzteblatt.de)
  • My professional practice had shown that the treatment of mental ill patient is just at border amid recover and failure of psychiatric medication. (healthyplace.com)
  • See Treatment and Medication for more details. (medscape.com)
  • The research has not been traditionally studied in cancer patients, and is believed to be the first to evaluate the treatment of heart failure using standard medication therapy in patients undergoing chemotherapy. (innovations-report.com)
  • Treatment for heart failure includes developing healthy eating and exercise habits, medication, and in some cases, surgery. (everydayhealth.com)
  • Heart Transplant If you have severe end-stage heart failure that can't be helped by medication or dietary and lifestyle changes, your doctors may recommend a heart transplant . (everydayhealth.com)
  • You will likely have to continue to take medication even if your heart failure resolves. (simstat.com)
  • What other possible medical/dietary/environmental issues could be responsible for so many treatment failures, if totally compliant with medication during treatment? (helico.com)
  • On multivariate analysis, treatment by reirradiation or chemotherapy alone and rN2 disease were independent factors that predicted poor survival, whereas treatment by reirradiation or chemotherapy alone was the only independent factor that predicted further relapse or failure. (nih.gov)
  • Resynchronization therapy is the biggest story in device therapy for heart failure," says Konstam, who is also president of the Heart Failure Society of America. (webmd.com)
  • The American College of Cardiology, American Heart Association, and Heart Failure Society of America maintain treatment guidelines for all types of heart failure. (healthcentral.com)
  • The findings were presented today at the Sixth Annual Scientific Meeting of the Heart Failure Society of America in Boca Raton by Dr. Jean-Bernard Durand, assistant professor in the Department of Cardiology and director of Cardiomyopathy Service at M. D. Anderson. (innovations-report.com)
  • If the kidneys fail completely, the only treatment options available may be dialysis or transplant. (rxlist.com)
  • During the treatment, blood travels out of the patient, through blood tubing, a dialysis machine, and a dialyzer (known collectively as the dialysis circuit), and back into the patient again. (dlife.com)
  • Home hemodialysis is also a treatment option, but because it requires a significant investment in both training and equipment, the majority of U.S. ESRD patients undergo dialysis in a center. (dlife.com)
  • Peritoneal dialysis is a home-based treatment and can be done at home, at work, at school or even during travel. (kidney.org)
  • In addition to gaining new understanding of congestive heart failure, and identifying potential treatment options, the researchers said they expect the model to help gain a better understanding of a range of other heart conditions. (upi.com)
  • 209,103 of these patients did not receive levothyroxine, 6560 were already being treated with levothyroxine, and 9007 started levothyroxine treatment after the diagnosis of heart failure. (thyroid.org)
  • Appropriate treatment can reduce your symptoms and dramatically slow the evolution of the disease, and many women go on to lead long, fulfilling lives after a diagnosis of heart failure. (simstat.com)
  • Accurate and reliable information about children's use of inhaled medications is needed because of the growing reliance on these drugs in the treatment of asthma and the excessive morbidity and mortality attributable to this disease. (nih.gov)
  • Until the 1980s, the standard treatments - digoxin, which strengthens heart contractions, and diuretics, which increase urine output - did nothing to reduce mortality, and little to relieve the symptoms of breathlessness, fatigue and swelling. (heraldnet.com)
  • About 10 per cent of people who have a heart attack (or myocardial infarction) will develop scarring and thickening of the heart wall that can lead to heart failure, which has a high mortality rate and its treatment is costly to the health system. (montrealgazette.com)
  • Although the researchers' initial analysis found that neither collaborative care method significantly reduced the rate of hospital readmissions or all-cause mortality among depressed heart failure patients, Rollman cautioned that additional analyses and longer follow-up are needed to confirm these findings. (upmc.com)
  • Apart from the two second generation beta blockers metoprolol and bisoprolol, carvedilol has also been shown to be effective in heart failure to reduce morbidity and mortality. (escardio.org)
  • The US Carvedilol study reported a 65 % mortality reduction in Class III or IV patients with heart failure when carvedilol added on usual care including digoxin, diuretics and ACE inhibitors (9). (escardio.org)
  • In patients that were prescribed conventional therapy for chronic heart failure including an ACE inhibitor, Atacand demonstrated additional mortality and morbidity benefits. (eurekalert.org)
  • This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field. (springer.com)
  • A health informatics specialist in Rwanda has developed a computer-based application to help clinicians reduce medical errors in managing HIV treatment failure. (nextbillion.net)
  • Mbituyumuremyi notes that in Rwanda, clinicians face challenges in managing transition to a new treatment if HIV is not suppressed, leading to delayed or unnecessary switching between alternative treatments, which could cause drug resistance in patients. (nextbillion.net)
  • CONCLUSIONS -Clinicians should change glucose-lowering treatments in type 2 diabetes much sooner or use treatments that are less likely to fail. (diabetesjournals.org)
  • A major but perhaps not widely appreciated contributor to glycemic burden is the response of clinicians to antihyperglycemic treatment failure. (diabetesjournals.org)
  • Clinicians should exercise caution in using azithromycin for treating incubating syphilis or syphilis infection until the risk and mechanism of failure are better understood. (cdc.gov)
  • Overall, these results are a reminder for all clinicians, not just cardiologists, to be mindful of their patients' mental health, as elevated depressive symptoms occurred in nearly half of all hospitalized heart failure patients and persisted in over one-third at two weeks following discharge," said Rollman. (upmc.com)
  • The "Treatment and Care for HIV-Positive Injecting Drug Users" training curriculum is designed for clinicians who provide treatment and care, including ART, for HIV-positive injecting drug users. (who.int)
  • In recent years it has been shown repeatedly that in evidence-based and prognosis-relevant treatment measures, a clear interaction exists between adherence and the subsequent prognosis. (aerzteblatt.de)
  • This article provides an overview of heart failure (HF) and pharmacological treatment of systolic left ventricular dysfunction. (nursingcenter.com)
  • With appropriate treatment, the dysfunction usually can be reversed. (emedicinehealth.com)
  • Importantly, Atacand is the first Angiotensin Receptor Blocker (ARB) to increase survival in chronic heart failure patients with left ventricular dysfunction, whether or not they are taking an ACE-inhibitor. (eurekalert.org)
  • If you're pulmonary artery pressures increases, you and your doctor can begin treatment earlier before your symptoms - shortness of breath, weight gain, swelling legs or feet, or coughing - appear. (promedica.org)
  • Shortness of breath can be a sign of many ailments, including heart failure, which affects approximately 5 million people in the U.S. Difficulty breathing is also a hallmark of COVID-19, which makes rapid diagnosis even more important. (dailypress.com)
  • Systolic heart failure is a form of heart failure in which the heart's lower chambers (ventricles) have become too weak to contract and pump enough blood to meet the body's needs, resulting in shortness of breath and other heart failure symptoms. (simstat.com)
  • 9. A method for the treatment of one or more symptoms associated with heart failure selected from the group comprising edema of lower limbs, pulmonary edema, dyspnea, liver enlargement, increased heart rate, reduced stroke volume, shortness of breath and exercise intolerance which comprises administering, in a daily dose, a cortisol antagonist to a mammalian subject, with the proviso that said cortisol antagonist is not clonidine. (google.es)
  • Despite improved treatment options, heart failure remains the third most common cause of death in Germany and the most common reason for hospitalization. (aerzteblatt.de)
  • patients with atrial fibrillation have a higher risk of hospitalization due to heart failure, a study found. (medicalnewstoday.com)
  • For Americans over 65, heart failure is the leading cause of hospitalization. (redorbit.com)
  • In 2017, the guidelines were updated to include a new treatment class: neprilysin inhibitors. (healthcentral.com)
  • All 16 patients received standard combination therapy for heart failure, which included ACE inhibitors, diuretics and the beta-blocking agent carvedilol, unless unable to tolerate therapy. (innovations-report.com)
  • 40 %) . When added to standard treatment including ACE-inhibitors, the carvedilol groupe showed a 23 % reduction in all cause mortailty (8). (escardio.org)
  • ACE inhibitors also slow the changes in the heart that cause heart failure to get worse, even in women who don't yet have heart failure symptoms. (simstat.com)
  • ACE inhibitors work better in whites than in African Americans, who may need other medications (such as hydralazine and isosorbide dinitrate) to ensure the best possible control of their heart failure. (simstat.com)
  • Good glycemic control has become even more important with earlier diagnosis and more aggressive cardiovascular prevention and treatment. (diabetesjournals.org)
  • Reducing disparities for heart failure prevention and care among racial, ethnic, and socioeconomic subgroups. (redorbit.com)
  • Learning more about the condition is the first step to successful prevention and effective treatment. (verywell.com)
  • If we don´t improve or reduce the incidence of heart failure by preventing and treating the underlying conditions, there will be a large monetary and health burden on the country," said Paul A. Heidenreich, MD, MS, a professor of medicine at Stanford University School of Medicine. (redorbit.com)
  • The researchers obtained data on heart failure hospitalizations through the database Premier Inc. (yaledailynews.com)
  • In addition to heart failure, researchers say the model can be used to observe other conditions by altering chemical and physiological changes to the organ in the model. (upi.com)
  • LOS ANGELES, June 24 (UPI) -- In order to better understand how conditions such as arrhythmia and heart failure manifest, researchers have created a virtual model to see the heart in action and test drugs to prevent adverse health events. (upi.com)
  • For the study, researchers reproduced digitally a previously validated electrophysiology model for the function of a healthy rabbit heart, focusing on congestive heart failure and the changes to heart function that cause the condition to develop. (upi.com)
  • The researchers analyzed bone marrow cells taken via biopsies from 77 patients with AML and found that the presence of FOXM1 in the cells' nuclei was a strong predictor of poor treatment outcome for individual patients. (news-medical.net)
  • In response, researchers at the University of Arizona College of Medicine - Phoenix are attempting to prevent heart failure after a heart attack with a novel treatment that targets fibroblasts, cells in connective tissue that produce collagen and play a critical role in healing. (news-medical.net)
  • Researchers at The University of Texas M. D. Anderson Cancer Center have found that cancer patients who develop heart failure as a result of chemotherapy treatment can be effectively treated, with the condition potentially reversed, when standard medicated therapy for heart failure is utilized. (innovations-report.com)
  • Similarly, the incidence of failure increased as the presenting T3 level increased. (springer.com)
  • 1 The rapidity of response to treatment with IVIG is gratifying, and it has significantly decreased the incidence of subsequent coronary aneurysms. (aappublications.org)
  • We retrospectively analyzed all children admitted for KD over a 3-year period to determine the incidence of failure to fully respond to IVIG and to report our experience treating these children. (aappublications.org)
  • Because our population is aging, it will become more common and the cost to treat heart failure will become a significant burden to the United States over the next 20 years unless something is done to reduce the age-specific incidence. (redorbit.com)
  • CHARM co-chairman, Professor Karl Swedberg, Göteborg University and Sahlgrenska University Hospital/Östra, Göteborg, Sweden introduced the rationale behind the CHARM Programme: "While the incidence of most cardiovascular disease is stabilising, chronic heart failure remains a serious and costly condition with patients being symptomatic and at risk of early death. (eurekalert.org)
  • You can develop heart failure because of existing heart disease, like coronary artery disease or hypertension, or from conditions that weaken the heart, like diabetes or excess alcohol use. (healthcentral.com)
  • We decided to use a retrospective database to conduct a prospective analysis of secondary treatment failure in type 2 diabetes. (diabetesjournals.org)
  • The aging population and an increase in the number of patients with conditions that contribute to the development of heart failure , like ischemic heart disease, hypertension and diabetes, drive this dramatic increase. (redorbit.com)
  • In addition, all the risk factors that normally increase the chances of heart disease, such as smoking, diabetes, and obesity, increase your risk of congestive heart failure. (medbroadcast.com)
  • With improved management of these tumors, there are more survivors with long-term sequelae of radiation and chemotherapy including growth failure. (aappublications.org)
  • We reviewed the records of 43 patients with synchronous locoregional failures of NPC who received salvage treatment or chemotherapy between November 1986 and January 2001. (nih.gov)
  • Seventeen patients received surgery for regional and/or local failures with or without combined radiotherapy (ST group), 14 patients received reirradiation to both local and regional disease (RT group), and 12 patients received palliative chemotherapy only (CT group). (nih.gov)
  • The 3-year relapse-free survival (RFS) rate and disease-specific survival (DSS) rate after salvage treatment or chemotherapy were 17% and 38%, respectively. (nih.gov)
  • In patients with more advanced disease, treatment by reirradiation alone or palliative chemotherapy is largely ineffective and is associated with a poor outcome. (nih.gov)
  • Until now, heart failure was thought to be irreversible in chemotherapy patients with many cardiologists advising patients who develop the condition to reduce their chemotherapy regimens," say Dr. Durand, lead investigator for the study. (innovations-report.com)
  • This data suggests that patients can continue their chemotherapy regimens, yet effectively reduce their risk of worsening heart failure and the eventual need for heart transplantation. (innovations-report.com)
  • Dr. Durand says that 30 percent to 50 percent of chemotherapy patients will develop heart failure. (innovations-report.com)
  • Dr. Durand presented today two retrospective studies evaluating the treatment of heart failure in chemotherapy patients. (innovations-report.com)
  • The data demonstrate that chemotherapy-induced heart failure may be reversible with standard medicated therapy for the condition," says Dr. Durand. (innovations-report.com)
  • The implications of this research could lead to better chemotherapy regimens for patients without concern for developing a potentially fatal condition as a result of their cancer treatment. (innovations-report.com)
  • Systolic heart failure occurs when the left ventricle fails to contract normally. (healthline.com)
  • FTT occurs when a child is either not receiving adequate calories or is unable to properly use the calories that are given, resulting in failure to grow or gain weight over a period of time. (nationwidechildrens.org)
  • Heart failure (HF) occurs when the heart can't pump enough blood to meet the body's needs, slowing blood flow and causing fluid to build up in the chest, lungs and limbs. (sharecare.com)
  • On the other hand, heart failure is a chronic, progressive condition, which occurs when the heart muscle is unable to pump enough blood to meet the body's needs for blood and oxygen. (news-medical.net)
  • Perform antiretroviral (ARV) drug-resistance testing when virologic failure occurs, while the patient is still taking the failing regimen, and before changing to a new regimen (AI*) . (nih.gov)
  • Virologic failure occurs as an incomplete initial response to therapy or as a viral rebound after virologic suppression is achieved. (nih.gov)
  • Congestive heart failure (CHF) occurs when the heart isn't able to pump blood normally. (medbroadcast.com)
  • The new regimen should include at least 2, but preferably 3, fully active ARV medications with assessment of anticipated ARV activity based on past treatment history and resistance test results (AII*) . (nih.gov)
  • Because infants with high plasma viral loads at initiation of therapy occasionally take longer than 6 months to achieve virologic suppression, some experts continue the treatment regimen for infants receiving ritonavir-boosted (LPV/r) -based therapy if viral load is declining but is still ≥200 copies/mL at 6 months and monitor closely for continued decline to virologic suppression soon thereafter. (nih.gov)
  • To facilitate treatment of early syphilis patients and their sexual contacts, certain disease-control programs have administered azithromycin as a single oral regimen. (cdc.gov)
  • To prospectively determine the virologic impact of switching treatment-experienced HIV-infected patients with virologic failure to a salvage regimen with or without a 12 week STI prior to the switch. (clinicaltrials.gov)
  • In treatment-experienced HIV patients who experience virologic failure, a STI prior to starting a salvage regimen will result in an improved virologic response and more prolonged vral suppression compared to immediate switching to a new regime. (clinicaltrials.gov)
  • Immediate Switch to Salvage Therapy: Patients randomized to the control arm will be switched immediately to a salvage regimen using the information from the treatment history and genotype results. (clinicaltrials.gov)
  • Structured Treatment Interruption: Patients randomized to the STI arm will have their present regimen stopped for 12 weeks and will have a genotype repeated in the 12th week. (clinicaltrials.gov)
  • A salvage regimen will be started at week 12 using the information from the treatment history and baseline genotype results. (clinicaltrials.gov)
  • Just adding one of the new drugs, Avastin, to a treatment regimen will increase costs to the patient of $8,000 per month. (positivearticles.com)
  • Your doctor can also use an X-ray to diagnose conditions other than heart failure that may explain your signs and symptoms. (mayoclinic.org)
  • Consult your GP or cardiologist if you have signs of heart failure or if your symptoms worsen. (medtronic.com)
  • Most women have few signs of premature ovarian failure. (mayoclinic.org)
  • What Are Congestive Heart Failure Symptoms and Warning Signs? (emedicinehealth.com)
  • Congestive heart failure can have the following major symptoms and signs. (emedicinehealth.com)
  • Heart failure is typically treated by loop diuretics, commonly known as water pills, which stimulate the kidneys to excrete excess salt and water to relieve fluid that builds up due to heart complications. (yaledailynews.com)
  • There is no actual damage to the kidneys early in the process with prerenal failure. (emedicinehealth.com)
  • The purpose of this study was to identify patterns and predictors of failure of RAI in patients with hyperthyroidism. (springer.com)
  • We estimated the glycemic burden that accumulates from treatment failure and describe the time course and predictors of failure. (diabetesjournals.org)
  • A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. (who.int)
  • For those Americans in the last stages of heart failure, we must also increase access to palliative and hospice care to reduce the suffering of their final years," she added. (redorbit.com)
  • I am wondering what to expect at the end stages of liver failure (due to cirrhosis). (medhelp.org)
  • The main goals of treating systolic heart failure are to relieve your symptoms, improve your quality of life, and slow down the progression of heart failure by preventing further damage to your heart. (simstat.com)
  • Heart failure and its complications are responsible for premature death in a proportion of sufferers and generally curtails the working life and range of activities which can be undertaken by the sufferer, as well significantly reducing overall quality of life. (google.es)
  • It may be that the degree of heart failure advances to the point where worsening symptoms no longer respond to conventional treatment, complications arise and recurrent hospital admissions are unavoidable. (chss.org.uk)
  • The presence of FOXM1, especially at high levels, is a strong predictor of worse treatment outcomes and decreased survival in patients with cancer. (news-medical.net)
  • These readings are the most accurate way to determine if your heart failure is getting worse. (promedica.org)
  • For patients diagnosed with severe heart failure the chances of surviving for more than five years are worse than many forms of cancer. (bhf.org.uk)
  • The idea of government failure is associated with the policy argument that, even if particular markets may not meet the standard conditions of perfect competition required to ensure social optimality, government intervention may make matters worse rather than better. (wikipedia.org)
  • Government failure (by definition) does not occur when government action creates winners and losers, making some people better off and others worse off than they would be without governmental regulation. (wikipedia.org)
  • A lot of the big advances that we've had in treating heart failure in the last few years has been with devices," says Marvin A. Konstam, MD, chief of cardiology and director of cardiovascular development at Tufts-New England Medical Center. (webmd.com)
  • Their findings may lead to advances in treatment for diseases like high blood pressure, congestive heart failure, and cirrhosis of the liver. (medindia.net)
  • Editorial: Treatment of liver failure. (bmj.com)
  • Hi all, My mother has end stage liver failure and is going through all the testing to b. (medhelp.org)
  • i think ive got liver failure due to alcohol, im not an alcoholic but drink 2-3 a day heavi. (medhelp.org)
  • Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. (wikipedia.org)
  • Almost all antiretroviral (ARV) management decisions for treatment failure are based on addressing virologic failure. (nih.gov)
  • Virologic failure is defined as a repeated plasma viral load ≥200 copies/mL after 6 months of therapy. (nih.gov)
  • Hoofnagle JH, Carithers RL Jr, Shapiro C, Ascher N. Fulminant hepatic failure: summary of a workshop. (medscape.com)
  • Fulminant hepatic failure. (medscape.com)
  • Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure. (medscape.com)
  • This is sub-divided into "fulminant hepatic failure", which requires onset of encephalopathy within 8 weeks, and "subfulminant", which describes onset of encephalopathy after 8 weeks but before 26 weeks. (wikipedia.org)
  • Congestive heart failure (CHF) is often the result of severe coronary artery disease , which decreases blood flow to the heart. (upmc.com)
  • Importantly, Atacand demonstrated this efficacy, along with a high level of tolerability, when taken as part of triple combination therapy that included an ACE-inhibitor and beta-blocker - standard treatments in patients with chronic heart failure. (eurekalert.org)
  • Heart failure, the only cardiovascular disease on the rise, affects 5 million people in the U.S. (heraldnet.com)
  • The breadth of application of this technology concerning the spectrum of cardiovascular disease is currently limited to treatment of ischemic cardiomyopathy. (medgadget.com)
  • Beta-adrenergic receptor blockers play an important role in the management of cardiovascular disease, including hypertension, ischemic heart disease and chronic heart failure. (escardio.org)
  • Treatment failures occur with any drug and aspirin is no exception. (innovations-report.com)
  • In patients with high cholesterol levels, aspirin in in normal doses has hardly any anti-clotting effects, whereas treatment with a statin (inhibitor of cholesterol) significantly reduces blood clotting. (innovations-report.com)
  • Less costly aspirin is as effective for heart failure patients with normal heart rhythm as other more expensive drugs, such as warfarin, according to breakthrough research published in today´s New England Journal of Medicine . (redorbit.com)
  • Since the overall risks and benefits are similar for aspirin and warfarin, the patient and his or her doctor are free to choose the treatment that best meets their particular medical needs. (redorbit.com)
  • The study shown here demonstrates that warfarin quite markedly reduces the risk of stroke associated with heart failure compared with aspirin, but at a cost of an increase in major hemorrhage," Dr. Andrew Clark, from the British Society for Heart Failure and the University of Hull, told BBC News . (redorbit.com)
  • The use of intravenous gammaglobulin (IVIG) with aspirin is standard treatment and successful in most patients. (aappublications.org)
  • All patients treated for KD between September 1, 1993 and September 30, 1996, who fulfilled criterion for KD 6 , ,7 were reviewed by 1 of us (C.A.W.). All patients were initially treated with 2 g/kg IVIG and aspirin (80-100 mg/kg/day in divided doses) until the second week of treatment, after which it was reduced to 5 mg/kg/day. (aappublications.org)
  • Sixty-two (95%) of 65 children with KD initially improved after treatment with IVIG and aspirin. (aappublications.org)
  • Failure of aspirin treatment after stroke. (ahajournals.org)
  • Out of 2231 consecutive patients who were admitted to the Tel Aviv Medical Center from May 1988 through December 1992 with the diagnosis of ischemic stroke, 129 admissions were due to recurrent ischemic strokes while the patients were already on aspirin, and these were defined as aspirin failures. (ahajournals.org)
  • Patients matched for aspirin dose and date of first stroke did not differ significantly in age (72.4 years in aspirin failures versus 74.2 years in the first control group) and sex (89 versus 94 men, respectively). (ahajournals.org)
  • Persistent or recurrent hyperthyroidism after treatment with radioactive iodine (RAI) is common and many patiedlxnts require either additional doses or surgery before they are cured. (springer.com)
  • To determine initial intravenous gammaglobulin (IVIG) treatment failures in Kawasaki disease (KD) and to report the outcome of retreatment and our use of pulse intravenous (IV) methylprednisolone and cyclophosphamide in patients with persistent KD. (aappublications.org)
  • BOSTON (AP) - Doctors are reporting surprising early success with a novel treatment they hope will one day cure congestive heart failure in thousands of dying patients: They shrink the bloated heart with drugs while an artificial pump temporarily takes over the workload. (sunjournal.com)
  • Targeting the cells responsible for collagen production and deposition represents an ideal and novel treatment approach,' Dr. Garvin said. (news-medical.net)
  • Einfeldt MN 2018 Long-term outcome in heart failure patients treated with levothyroxine: an observational nationwide cohort study. (thyroid.org)
  • This stage-based classification system uses letters A to D. The system includes a category for people who are at risk of developing heart failure. (mayoclinic.org)
  • Smoking - people who smoke regularly run a significantly higher risk of developing heart failure. (medicalnewstoday.com)
  • Heart attack survivors are at greater risk of developing heart failure, a chronic condition in which more than half of those diagnosed will die within five years. (news-medical.net)
  • Though small, the British study more than tripled the usual recovery rate for patients with severe heart failure, a common killer once viewed as unstoppable. (sunjournal.com)
  • Richard's story shows the devastating impact severe heart failure can have on a person's quality of life. (bhf.org.uk)
  • One way of helping a person with severe heart failure is to fit a biventricular pacemaker. (bhf.org.uk)
  • In a second retrospective study, Dr. Durand and investigators reviewed the medical records from 16 cancer outpatients with mild to severe heart failure, diagnosed at initial evaluation in M. D. Anderson s cardiomyopathy clinic. (innovations-report.com)
  • Carvedilol and nebivolol are the third generation beta blockers of choice for heart failure together with the second generation beta blockers bisoprolol and metoprolol succinate. (escardio.org)
  • Bikdeli said these three medications - furosemide, bumetanide and torsemide - have been available for over 10 years, but nobody has conducted research to investigate potential differences between them and determine the most effective treatment. (yaledailynews.com)
  • In patients with advanced heart failure, these medications and treatments ultimately become insufficient and doctors may recommend other treatments such as a heart transplant or the use of a Ventricular Assist Device (VAD) to improve the health and quality of life of these patients. (medtronic.com)
  • Even with medications your symptoms can come back, and additional treatment may be needed. (simstat.com)
  • Heart failure is treated with a combination of medications, lifestyle changes and, if necessary, surgical procedures. (simstat.com)
  • Symptoms include angina, and that of heart failure. (medindia.net)
  • The "survive 3y" branches include all patients who survived at least three years after the first treatment, and the "death" branches include all patients who died within those three years. (nih.gov)
  • The conversion of primary health centres (PHCs) into family health centres (FHCs) is the key, where medical officers will get special training to become family doctors and look out for symptoms of NCDs (non-communicable diseases) which include diabetics, hypertension, cancer and heart failure, said the minister. (indiatimes.com)
  • The ability to perform this intervention in a larger subset of heart failure patients will require us to include patients that are not solely dependent on surgery for tissue samples. (medgadget.com)
  • Examples of government failure include regulatory capture and regulatory arbitrage. (wikipedia.org)
  • Demand-side failures include preference-revelation problems and the illogics of voting and collective behaviour. (wikipedia.org)