A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
Therapy with two or more separate preparations given for a combined effect.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Substances that reduce the growth or reproduction of BACTERIA.
The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
The return of a sign, symptom, or disease after a remission.
A group of SESQUITERPENES and their analogs that contain a peroxide group (PEROXIDES) within an oxepin ring (OXEPINS).
A 4-aminoquinoline compound with anti-inflammatory properties.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A family of diphenylenemethane derivatives.
A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM). It is most prevalent in the tropics and subtropics.
A condition of substandard growth or diminished capacity to maintain normal function.
Elements of limited time intervals, contributing to particular results or situations.
A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
The ability of viruses to resist or to become tolerant to chemotherapeutic agents or antiviral agents. This resistance is acquired through gene mutation.
Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Substances that are destructive to protozoans.
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE.
Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
Arsenical used in trypanosomiases. It may cause fatal encephalopathy and other undesirable side effects.
The process of observing, recording, or detecting the effects of a chemical substance administered to an individual therapeutically or diagnostically.
A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
An anabolic steroid that has been used in the treatment of male HYPOGONADISM, delayed puberty in males, and in the treatment of breast neoplasms in women.
The quantity of measurable virus in a body fluid. Change in viral load, measured in plasma, is sometimes used as a SURROGATE MARKER in disease progression.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Drug regimens, for patients with HIV INFECTIONS, that aggressively suppress HIV replication. The regimens usually involve administration of three or more different drugs including a protease inhibitor.
A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
A republic in eastern Africa, south of SUDAN and west of KENYA. Its capital is Kampala.
A hemoflagellate subspecies of parasitic protozoa that causes Gambian or West African sleeping sickness in humans. The vector host is usually the tsetse fly (Glossina).
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
A species of gram-negative bacteria originally isolated from urethral specimens of patients with non-gonoccocal URETHRITIS. In primates it exists in parasitic association with ciliated EPITHELIAL CELLS in the genital and respiratory tracts.
An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC
Disease having a short and relatively severe course.
An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)
A metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Pathological processes involving the PHARYNX.
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.
Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Infections with bacteria of the genus STAPHYLOCOCCUS.
Voluntary cooperation of the patient in following a prescribed regimen.
A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects.
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
The giving of drugs, chemicals, or other substances by mouth.
Simultaneous resistance to several structurally and functionally distinct drugs.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis.
An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
A country consisting of the eastern half of the island of New Guinea and adjacent islands, including New Britain, New Ireland, the Admiralty Islands, and New Hanover in the Bismarck Archipelago; Bougainville and Buka in the northern Solomon Islands; the D'Entrecasteaux and Trobriand Islands; Woodlark (Murua) Island; and the Louisiade Archipelago. It became independent on September 16, 1975. Formerly, the southern part was the Australian Territory of Papua, and the northern part was the UN Trust Territory of New Guinea, administered by Australia. They were administratively merged in 1949 and named Papua and New Guinea, and renamed Papua New Guinea in 1971.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Cytochromes of the b group that have alpha-band absorption of 563-564 nm. They occur as subunits in MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
MYCOBACTERIUM infections of the lung.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs.
The practice of replacing one prescribed drug with another that is expected to have the same clinical or psychological effect.
The relationship between the dose of an administered drug and the response of the organism to the drug.
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
A broad-spectrum antimicrobial carboxyfluoroquinoline.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.
The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Proteins found in any species of protozoan.
A republic in central Africa, east of the REPUBLIC OF THE CONGO, south of the CENTRAL AFRICAN REPUBLIC and north of ANGOLA and ZAMBIA. The capital is Kinshasa.
Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Deoxyribonucleic acid that makes up the genetic material of protozoa.
Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
The ability of viruses to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance phenotype may be attributed to multiple gene mutation.
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).
1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. Often used in conjunction with iodinated organic compounds as contrast medium.
A pyrazine that is used therapeutically as an antitubercular agent.
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Infection of the lung often accompanied by inflammation.
A treatment method in which patients are under direct observation when they take their medication or receive their treatment. This method is designed to reduce the risk of treatment interruption and to ensure patient compliance.
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
A serotype of SALMONELLA ENTERICA that causes mild PARATYPHOID FEVER in humans.
A republic in eastern Africa, south of ETHIOPIA, west of SOMALIA with TANZANIA to its south, and coastline on the Indian Ocean. Its capital is Nairobi.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM.
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
The confinement of a patient in a hospital.
Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.
Non-steroidal chemical compounds with abortifacient activity.
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Formerly known as Siam, this is a Southeast Asian nation at the center of the Indochina peninsula. Bangkok is the capital city.
A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
An infant during the first month after birth.
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
A cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A republic in southern Africa, southwest of DEMOCRATIC REPUBLIC OF THE CONGO and west of ZAMBIA. Its capital is Luanda.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Tumors or cancer of the human BREAST.
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
A republic in southern Africa, south of DEMOCRATIC REPUBLIC OF THE CONGO and TANZANIA, and north of ZIMBABWE. Its capital is Lusaka. It was formerly called Northern Rhodesia.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Discontinuance of care received by patient(s) due to reasons other than full recovery from the disease.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Non-susceptibility of an organism to the action of the cephalosporins.
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Cluster survey evaluation of coverage and risk factors for failure to be immunized during the 1995 National Immunization Days in Egypt. (1/4460)

BACKGROUND: In 1995, Egypt continued to experience endemic wild poliovirus transmission despite achieving high routine immunization coverage with at least three doses of oral poliovirus vaccine (OPV3) and implementing National Immunization Days (NIDs) annually for several years. METHODS: Parents of 4188 children in 3216 households throughout Egypt were surveyed after the second round of the 1995 NIDs. RESULTS: Nationwide, 74% of children are estimated to have received both NID doses, 17% one NID dose, and 9% neither NID dose. Previously unimmunized (47%) or partially immunized (64%) children were less likely to receive two NID doses of OPV than were fully immunized children (76%) (P < 0.001). Other risk factors nationwide for failure to receive NID OPV included distance from residence to nearest NID site >10 minute walk (P < 0.001), not being informed about the NID at least one day in advance (P < 0.001), and residing in a household which does not watch television (P < 0.001). Based on these findings, subsequent NIDs in Egypt were modified to improve coverage, which has resulted in a marked decrease in the incidence of paralytic poliomyelitis in Egypt. CONCLUSIONS: In selected situations, surveys can provide important information that is useful for planning future NIDs.  (+info)


nvited commentary: vaccine failure or failure to vaccinate?  (+info)


aning of vaccine-induced immunity: is it a problem in Africa?  (+info)

Early mycological treatment failure in AIDS-associated cryptococcal meningitis. (4/4460)

Cryptococcal meningitis causes significant morbidity and mortality in persons with AIDS. Of 236 AIDS patients treated with amphotericin B plus flucytosine, 29 (12%) died within 2 weeks and 62 (26%) died before 10 weeks. Just 129 (55%) of 236 patients were alive with negative cerebrospinal fluid (CSF) cultures at 10 weeks. Multivariate analyses identified that titer of cryptococcal antigen in CSF, serum albumin level, and CD4 cell count, together with dose of amphotericin B, had the strongest joint association with failure to achieve negative CSF cultures by day 14. Among patients with similar CSF cryptococcal antigen titers, CD4 cell counts, and serum albumin levels, the odds of failure at week 10 for those without negative CSF cultures by day 14 was five times that for those with negative CSF cultures by day 14 (odds ratio, 5.0; 95% confidence interval, 2.2-10.9). Prognosis is dismal for patients with AIDS-related cryptococcal meningitis. Multivariate analyses identified three components that, along with initial treatment, have the strongest joint association with early outcome. Clearly, more effective initial therapy and patient management strategies that address immune function and nutritional status are needed to improve outcomes of this disease.  (+info)

Association of plasma fibrinogen concentration with vascular access failure in hemodialysis patients. (5/4460)

BACKGROUND: Elevated plasma fibrinogen is an important risk factor for coronary artery disease in the general population and patients with chronic renal failure. High plasma fibrinogen may trigger thrombus formation in arteriovenous fistulas. We performed a prospective, cohort study to evaluate the association of plasma fibrinogen concentration with vascular access failure in patients undergoing long-term haemodialysis. METHODS: Between September 1989 and October 1995, 144 patients underwent a vascular access operation. In March 1997, 102 patients (56 M, 46 F) who had been followed up for more than 18 months (median; 37 months, range; 18-102 months) were included in the study. The median age of the patients was 52 years (range; 19-78 years). In 35 patients, renal disease was secondary to diabetes mellitus. The type of vascular access was a polytetrafluoroethylene (PTFE) graft in 17 patients. Seventy-seven patients received recombinant human erythropoietin (r-HuEPO) therapy during the follow-up period. Plasma fibrinogen, albumin, total cholesterol, hematocrit, platelets and creatinine were measured at the time of operation. Vascular access failure was defined as the occurrence of complications requiring transluminal angioplasty, thrombolytic therapy or surgical repair. RESULTS: Thirty-eight patients had at least one vascular access failure and the incidence was 0.3 (range; 0-2.4) episodes per patient-year. The survival rate of vascular access was 78% (native fistula; 80%, PTFE graft; 71%) after 12 months and 70% (native fistula; 73%, PTFE graft; 51%) after 24 months. Older age, a PTFE graft, r-HuEPO therapy, higher hematocrit, lower albumin and higher fibrinogen levels were significantly associated with vascular access failure, whereas gender, diabetes mellitus, total cholesterol and platelet count were not. Plasma fibrinogen was inversely correlated with albumin (r=-0.38, P=0.001). The cumulative vascular access survival was significantly lower in patients with high plasma fibrinogen levels (> or = 460 mg/dl) compared with patients with low levels (< 460 mg/dl) (P=0.007). Independent risk factors for vascular access failure analysed by Cox's proportional hazards model were older age (RR; 1.36 by 10-year increment), higher fibrinogen level (RR; 1.20 by 100 mg/dl increment), PTFE graft (RR; 2.28) and r-HuEPO therapy (RR; 3.79). CONCLUSION: High plasma fibrinogen level is an independent risk factor for vascular access failure in haemodialysis patients.  (+info)

Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaounde, Cameroon. (6/4460)

The usefulness of an isotopic in vitro assay in the field was evaluated by comparing its results with the therapeutic response determined by the simplified WHO in vivo test in symptomatic Cameroonian patients treated with chloroquine. Of the 117 enrolled patients, 102 (87%) completed the 14-day follow-up, and 95 isolates obtained from these patients (46 children, 49 adults) yielded an interpretable in vitro test. A total of 57 of 95 patients (60%; 28 children and 29 adults) had an adequate clinical response with negative smears (n = 46) or with an asymptomatic parasitaemia (n = 11) on day 7 and/or day 14. The geometric mean 50% inhibitory concentration of the isolates obtained from these patients was 63.3 nmol/l. Late and early treatment failure was observed in 29 (30.5%) and 9 (9.5%) patients, respectively. The geometric mean 50% inhibitory concentrations of the corresponding isolates were 173 nmol/l and 302 nmol/l. Among the patients responding with late and early treatment failure, five isolates and one isolate, respectively, yielded a discordant result (in vivo resistance and in vitro sensitivity). The sensitivity, specificity, and predictive value of the in vitro test to detect chloroquine-sensitive cases was 67%, 84% and 86%, respectively. There was moderate concordance between the in vitro and in vivo tests (kappa value = 0.48). The in vitro assay agrees relatively well with the therapeutic response and excludes several host factors that influence the results of the in vivo test. However, in view of some discordant results, the in vitro test cannot substitute for in vivo data on therapeutic efficacy. The only reliable definition of "resistance" in malaria parasites is based on clinical and parasitological response in symptomatic patients, and the in vivo test provides the standard method to determine drug sensitivity or resistance as well as to guide national drug policies.  (+info)

Outcome and predictors of failure of highly active antiretroviral therapy: one-year follow-up of a cohort of human immunodeficiency virus type 1-infected persons. (7/4460)

The outcome and predictors of virologic treatment failure of highly active antiretroviral therapy (HAART) were determined for 271 human immunodeficiency virus (HIV)-infected protease inhibitor-naive persons. During a follow-up of 48 weeks after the initiation of HAART, 6.3% of patients experienced at least one new AIDS-defining event, and 3.0% died. Virologic treatment failure occurred in 40% (indinavir, 27%; ritonavir, 30%; saquinavir, 59%; ritonavir plus saquinavir, 32%; chi2, P=.001). Risk factors for treatment failure were baseline plasma HIV-1 RNA (odds ratio [OR], 1.70 per log10 copies increase in plasma HIV-1 RNA), baseline CD4 cell count (OR, 1. 35 per 100 CD4 cells/mm3 decrease), and use of saquinavir versus other protease inhibitors (OR, 3.21). During the first year of treatment, 53% of all patients changed (part of) their original HAART regimen at least once. This was significantly more frequent for regimens containing saquinavir (62%; 27% for virologic failure) or ritonavir (64%; 55% for intolerance) as single protease inhibitor.  (+info)

Isolated femoropopliteal bypass graft for limb salvage after failed tibial reconstruction: a viable alternative to amputation. (8/4460)

PURPOSE: Femoropopliteal bypass grafting procedures performed to isolated popliteal arteries after failure of a previous tibial reconstruction were studied. The results were compared with those of a study of primary isolated femoropopliteal bypass grafts (IFPBs). METHODS: IFPBs were only constructed if the uninvolved or patent popliteal segment measured at least 7 cm in length and had at least one major collateral supplying the calf. When IFPB was performed for ischemic lesions, these lesions were usually limited to the digits or small portions of the foot. Forty-seven polytetrafluoroethylene grafts and three autogenous reversed saphenous vein grafts were used. RESULTS: Ankle brachial pressure index (ABI) increased after bypass grafting by a mean of 0.46. Three-year primary life table patency and limb-salvage rates for primary IFPBs were 73% and 86%, respectively. All eight IFPBs performed after failed tibial bypass grafts remained patent for 2 to 44 months, with patients having viable, healed feet. CONCLUSION: In the presence of a suitable popliteal artery and limited tissue necrosis, IFPB can have acceptable patency and limb-salvage rates, even when a polytetrafluoroethylene graft is used. Secondary IFPB can be used to achieve limb salvage after failed tibial bypass grafting.  (+info)

Management of Virologic Treatment Failure. The approach to management and subsequent treatment of virologic treatment failure will differ depending on the etiology of the problem. While the causes of virologic treatment failure may be multifactorial, nonadherence plays a role in most cases. Assessment of a child with suspicion of virologic treatment failure should include evaluation of adherence to therapy and medication intolerance, confirmation that prescribed dosing is correct for all medications in the regimen, consideration of pharmacokinetic (PK) explanations of low drug levels or elevated and potentially toxic levels, and evaluation of suspected drug resistance (see Antiretroviral Drug-Resistance Testing in the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents). The main barrier to long-term maintenance of sustained virologic suppression in adults and children is incomplete adherence to medication regimens, with subsequent emergence of viral ...
Management of Virologic Treatment Failure. The approach to management and subsequent treatment of virologic treatment failure will differ depending on the etiology of the problem. While the causes of virologic treatment failure may be multifactorial, nonadherence plays a role in most cases. Assessment of a child with suspicion of virologic treatment failure should include evaluation of adherence to therapy and medication intolerance, confirmation that prescribed dosing is correct for all medications in the regimen, consideration of pharmacokinetic (PK) explanations of low drug levels or elevated and potentially toxic levels, and evaluation of suspected drug resistance (see Antiretroviral Drug-Resistance Testing in the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents). The main barrier to long-term maintenance of sustained virologic suppression in adults and children is incomplete adherence to medication regimens, with subsequent emergence of viral ...
CONTEXT: Presence of low-frequency, or minority, human immunodeficiency virus type 1 (HIV-1) drug resistance mutations may adversely affect response to antiretroviral treatment (ART), but evidence regarding the effects of such mutations on the effectiveness of first-line ART is conflicting.. OBJECTIVE: To evaluate the association of preexisting drug-resistant HIV-1 minority variants with risk of first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral virologic failure.. DATA SOURCES: Systematic review of published and unpublished studies in PubMed (1966 through December 2010), EMBASE (1974 through December 2010), conference abstracts, and article references. Authors of all studies were contacted for detailed laboratory, ART, and adherence data.. STUDY SELECTION AND DATA ABSTRACTION: Studies involving ART-naive participants initiating NNRTI-based regimens were included. Participants were included if all drugs in their ART regimen were fully active by standard HIV ...
Virologic failure occurs in a large proportion of individuals receiving treatment with combination antiretroviral therapy. Studies suggest that treatment interruption prior to initiation of a multiple-drug rescue regimen may improve virologic response in individuals who have failed several prior antiretroviral regimens. Other studies suggest there is a virologic benefit derived from using genotypic or phenotypic resistance testing in selecting salvage therapy regimens for patients failing antiretroviral therapy. This study tests the hypothesis that salvage regimens selected on the basis of HIV-1 resistance genotype, phenotype [AS PER AMENDMENT 02/19/02: virtual phenotype], and treatment history will be more effective if there is a period of treatment interruption before initiating that regimen.. Patients continue their antiretroviral therapy until randomization. Based on the results of the pre-entry genotype and phenotype [AS PER AMENDMENT 02/19/02: virtual phenotype] tests and treatment ...
Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy ...
Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy ...
1. Torres et al performed an RCT in 3 Spanish hospitals over 8 years. 120 patients with severe CAP (CRP , 150mg/l) were given intravenous bolus of 0.5 mg/kg per 12 hours of methylprednisolone or placebo for 5 days, started within 36 hours of hospital admission.Treatment failure was the primary outcome.. (Early treatment failure was development of shock, new need for mechanical ventilation , or death within 72 hours. Late treatment failure defined as worse CXR, persistence of severe respiratory failure, or any early treatment failure criteria between 72 hours and 120 hours.). There was less treatment failure in the steroid group (13 v 31%). Looking more closely it was the late treatment failure that was more affected, particularly the occurrence of septic shock. No statistically significant difference in hyperglycaemia.. Only 120 patients in 8 years raises concerns about recruitment and consequently external validity. Also there was no mortality difference between the groups - although the ...
Sputum samples from ten individuals were positive for acid-fast bacilli. Three of these individuals were HIV-positive, and one of these people was newly diagnosed with HIV thanks to the community health campaign.. Nine of the TB diagnoses were new; the other case had previously been detected at a local health centre. Six of the new cases had microscopy results suggesting their TB was highly contagious. Overall, 0.31% of people were newly diagnosed with TB. The number of people needed to screen using symptoms and microscopy to identify a single new case was 3024. The number of people with prolonged cough who required screening with microscopy to identity a new case was 320, the figure falling to 80 per case for HIV-positive people with chronic cough.. All nine people with newly detected TB were linked to care and initiated TB therapy. This treatment was completed by six people. One individual experienced treatment failure and initiated a second-line regimen; one individual was lost to follow-up; ...
Objectives: Better understanding of the dynamics of HIV reservoirs under ART is a critical step to achieve a functional HIV cure. Our objective was to assess the genetic diversity of archived HIV-1 DNA over 48 weeks in blood cells of individuals starting treatment with a dolutegravir-based regimen. Methods: Eighty blood samples were prospectively and longitudinally collected from 20 individuals (NCT02557997) including: acutely (n = 5) and chronically (n = 5) infected treatment-naive individuals, as well as treatment-experienced individuals who switched to a dolutegravir-based regimen and were either virologically suppressed (n = 5) or had experienced treatment failure (n = 5 ...
Hello and thanks for posting. Since you never really experienced treatment failure (or drug resistance), youd be considered on \
Some see admission of problems with bipolar disorder indicative of treatment failure. Bipolar pain doesnt indicate treatment failure. Breaking Bipolar blog by
High failure rate of OCZ SSDs yields answers that raise troubling questions - SSDs are like a bad drug. Theyre the best improvement one can make to a PC, but... My 4th OCZ SSD failed today at a remote site. With 4 out of 13 dr
View Notes - LAB 9 v2 from CS 1371 at Georgia Tech. LAB 9 NOTE: These labs are known for high failure rates. Therefore, if I show an example using data, a graph, etc yours may be totally different
Summer Sky Texas Inpatient Alcohol & Drug Rehabs, is relapse an Indicator of Treatment Failure, Medical Detox, 30-day rehab, 60-day rehab, 90-day rehabs
CAPE TOWN, South Africa -- The thiazolidinedione Avandia (rosiglitazone) has a more durable response than two older oral type 2 diabetes agents, but it was more expensive and had more side effects, re
Use the machine learning power of Sauce Failure Analytics to uncover errors and inefficiencies in your tests to improve your testing process.
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Many COVID drugs are failing. Natural medicine may hold the key-but can government cronyism be overcome? Action Alert! A large analysis has found that…
Another once-promising Alzheimer's drug has just been tossed on the pharmaceutical scrap heap. This time it's a drug called bapineuzumab. Like
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Definition for Trend Analysis: The process of analysing data to identify underlying longer-term trends (e.g., failure patterns). Used in Incident and Problem Management, it is also
I spent my morning unsuccessfully catching up on work. I was off to a good start, but then shooting pains started ripping through my left leg. At first I thought it might be a heart attack, but then I remembered...
TY - JOUR. T1 - Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy. AU - Lorch, Anja. AU - Beyer, Jörg. AU - Kramar, Andrew. AU - Einhorn, Lawrence H.. AU - Necchi, Andrea. AU - Massard, Christophe. AU - De Giorgi, Ugo. AU - Flechon, Aude. AU - Margolin, Kim A.. AU - Lotz, Jean Pierre. AU - Germa, Jose Ramon Lluch. AU - Powles, Thomas. AU - Kollmannsberger, Christian K.. AU - Bascoul-Mollevi, Caroline. PY - 2010/11/20. Y1 - 2010/11/20. N2 - Purpose: To develop a prognostic model in patients with germ cell tumors (GCT) who experience treatment failure with cisplatin-based first-line chemotherapy. Patients and Methods: Data from 1,984 patients with GCT who progressed after at least three cisplatin-based cycles and were treated with cisplatin-based conventional-dose or carboplatin-based high-dose salvage chemotherapy was retrospectively collected from 38 centers/groups worldwide. One thousand five hundred ...
Ekloef and Schmidt Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine2012, 20(Suppl 2):P10http://www.sjtrem.com/content/20/S2/P10 Community-acquired pneumonia: a comparisonof clinical treatment failure in patients treatedwith either penicillin or cefuroximeJosefin Ekloef*, Thomas A Schmidt From 4th Danish Emergency Medicine ConferenceRoskilde, Denmark. 25-26 November 2011 cefuroxime. Forty percent of the patients treated with National and local guidelines in the Emergency depart- penicillin experienced CTF compared to 17% in the ment (ED) at Holbaek hospital recommend penicillin as group treated with cefuroxime (p=0.347). Patients were first-line treatment of community-acquired pneumonia followed for 9 days. At 5 days, a survival rate without (CAP). Nevertheless, the use of cefuroxime seem to be CTF was estimated to 0,75 for cefuroxime and 0.54 for substantial when admitting patients with CAP ...
Southern Africa has the highest prevalence of HIV worldwide, and South Africa has the highest number of HIV infected people. South Africa and other resource-limited countries provide antiretroviral therapy (ART) for people with HIV, with limited, standardized regimens for first line and second line. Patients who fail first line treatment are put on second line regimens, yet options for third line are very limited. The first study looks at predictors of first line treatment failure in South Africa and develops a predictive model that can estimate absolute risk of treatment failure over 5 years on ART, given a baseline profile of clinical and demographic factors. The model was developed with accelerated failure time models, using predictors that maximized discrimination between patients. The model can be used to identify patients who need adherence interventions, and to estimate how changes in baseline parameters in the population influence long-term need for second line ART. The second study ...
Treatment failure is a serious problem facing some national tuberculosis [TB] control programmes. Irregularity of treatment is a factor that can lead to treatment failure. A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. We interviewed 119 people with treatment failure and an equal number of cured cases [controls] and their families regarding sociodemographic characteristics, information about TB, information about drugs, treatment compliance, family support and patient-family interaction. Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid ...
Our study indicates that 7% of patients with type 1 autoimmune hepatitis deteriorate during corticosteroid therapy and that treatment failure is associated with onset at an early age, acute presentation, hyperbilirubinemia, HLA DRB1*03, and a MELD score of at last 12 points. We could not ascribe the treatment failure to transition of the autoimmune hepatitis to another condition, and only 1 patient developed fatty liver disease, in whom treatment failure might have related to a superimposed or concurrent disease. Treatment failure was associated with a poor prognosis despite high-dose corticosteroid treatment, 7 patients (50%) either died of liver-related causes or required transplantation, and only 2 patients (14%) achieved remission.. Previous studies have indicated the importance of using disease severity, shown by histological pattern and laboratory features, to identify patients who have a poor prognosis if they are untreated.56 These findings, however, have not reliably identified those ...
Background: Timely detection of treatment failure with subsequent switch to second-line regimen reduces mortality among HIV infected people on antiretroviral therapy (ART). This paper aims to investigate the detection of immunological treatment failure and switch rate to second line regimen in Ethiopia. Methods: A retrospective cohort study was conducted among HIV infected patients (age > 15 years) who initiated ART between 2007 and 2009. The required data were collected from patient registers and formats. Data were entered and validated using EpiData software and then exported to SPSS version 20.0 for analysis. Odds ratio with 95 % CI was used to assess whether immunological treatment failure was associated with experiencing unfavorable treatment outcomes (death or lost to follow up). Results: Records of 293 patients were reviewed with a total of 1545 Person-Years of Observation (PYO). The median baseline CD4 count was 115 cells/mm3 (IQR: 64-176). A total of 46 (15.7 %) patients experienced ...
Good clinical activity for lenalidomide in R/R MCL patients after ibrutinib therapy failure Multicenter observational MCL-004 study
article{a788131c-c8d3-451e-9c12-43ec2f617e36, abstract = {,p,Background: Early identification of virological failure (VF) limits occurrence and spread of drug-resistant viruses in patients receiving antiretroviral treatment (ART). Viral load (VL) monitoring is therefore recommended, but capacities to comply with this are insufficient in many low-income countries. Clinical algorithms might identify persons at higher likelihood of VF to allocate VL resources. Objectives: We aimed to construct a VF algorithm (the Viral Load Testing Criteria; VLTC) and compare its performance to the 2013 WHO treatment failure criteria. Methods: Subjects with VL results available 1 year after ART start (n = 494) were identified from a cohort of ART-naïve adults (n = 812), prospectively recruited and followed 2011-2015 at Ethiopian health centres. VF was defined as VL≥1000 copies/mL. Variables recorded at the time of sampling, with potential association with VF, were used to construct the algorithm based on ...
CrossRefexternal icon PubMedexternal icon https://xo-review.com/maxalt-online-usa/ About maxalt serotonin Healthy People. Mumps Outbreaks Still OccurAfter the U. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. You should avoid travel to the extent of such systems include health department website. Testing the weathering explanation for experiencing flu symptoms for the five CDC Best Practice categories separately, we found real per capita spending on tobacco control programs and directly funded city health departments immediately if you are leaving the CDC rapid development of the 30 Days to Slow the Spread of SARS-CoV-2 viral RNA is unlikely to affect many areas.. Other common precipitating circumstances of possible clinical treatment failure is highly suspected, consider maxalt serotonin specialized testing to ensure that you are leaving the CDC website. As an alternative to colonoscopy and any venues where the people you know during the ...
Primary objective To investigate the H. pylori eradication rate obtained by each second-line regimen, stratifying these results by the first-line treatment previously used.. Secondary objectives To study the effect on the eradication success rate of different doses of the drugs used in the same type of therapy and the effect of the length of the therapies. Moreover, we will study the differences in the efficacy of treatments by sub-analysis of the following factors:. ...
Antiretroviral therapy; Immunological failure; Loss to follow-up; Malawi; Marginal structural models; Mortality; Second-line therapy; Treatment failure; Viral load monitoring; ...
The Haematology Department Protocols and Guidelines (the Red Book) are intended as a guide for registered health professionals to communicate guidelines and share best practices with supporting health professionals within New Zealand district health boards. They are not intended to be provided to or used as a reference for patients or non-registered health professionals. All health professionals must exercise their own clinical judgement and use pertinent clinical data when treating patients. The authors and editors of this publication have checked with sources believed to be reliable in their effort to provide information that is complete and in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical science, neither the authors, editors, publisher, nor any other party who has been involved in preparing or publishing this work warrants that the information contained in it is accurate or complete in every respect. ...
(2015) Teshome, Tefera. BMC Immunology. Background: Timely detection of treatment failure with subsequent switch to second-line regimen reduces mortality among HIV infected people on antiretroviral therapy (ART). This paper aims to investigate the detection of immunological treatment failure and ...
Diagnosed with leukemia this year 2010, she experienced treatment that put her in remission, only to have her cancers come back a year . 5 later, more stubborn
Health, ...TUESDAY April 19 (HealthDay News) -- About 1 in 8 children infected w...That drug failure rate is higher than in adults and highlights the cha...Virological failure occurs when drugs can no longer reduce the amount ...The study included more than 1000 HIV-positive children in several Eu...,Children,With,HIV,at,Higher,Risk,of,Drug,Resistance,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
AUTHOR = {Lehmann, Clara and D{\a}umer, Martin and Bousaad, Ibrahim and Sing, Tobias and Beerenwinkel, Niko and Lengauer, Thomas and Schmeisser, Norbert and Wyen, Christoph and F{\a}tkenheuer, Gerd and Kaiser, Rolf ...
Bamlanivimab was authorized for use in relation to the COVID-19 pandemic, in accordance with the Interim Order Respecting the Importation, Sale and Advertising of Drugs for Use in Relation to COVID-19. The CPM for bamlanivimab was updated on 14 April 2021 with information concerning SARS-CoV-2 variants of concern.
This is another Pavilion G7 model, with assorted HIGH failures encountered during certification of 12.04.2 with various tests that use fwts. I have attached the batch run log and the suspend_30_cycles log. There were also errors in the Hibernate log, but they were identical to the ones in the suspend log regaring hp_wmi ProblemType: Bug DistroRelease: Ubuntu 12.04 Package: linux-image-3.5.0-25-generic 3.5.0-25.39~precise1 ProcVersionSignature: Ubuntu 3.5.0-25.39~precise1-generic Un...
Low-level HIV viral load, above the limit of detection, is an important warning signal for future treatment failure and World Health Organization guidelines on spotting treatment failure need to be revised to encourage greater vigilance and swifter action by healthcare providers in lower- and middle-income settings, investigators report in The Lancet Infectious Diseases. The study ...
While the new treatments for hepatitis C have improved dramatically in terms of cure rates and side effects (and pharmaceutical companies bottom-line), there are still patients who do not respond, especially those with genotype 3. A recent study (Hepatology 2015; 61: 56-65) has provided some information into why this is happening. A division of the…
Exosomes have diameter within the range of 30-100nm and spherical to cup-shaped nanoparticles with specific surface molecular characteristics, such as CD9 and
North Jersey Health & Wellness specializes in treating patients with a wide variety of mental illnesses, health issues and more. With 4 convenient locations, NJHW is the perfect practice for you and your family.
This thesis will explore research done to date on Bad Therapy, in an attempt to identify what are the common causes of therapy failure and typical therapy mistakes. There is a wide body of literature and research that ...
RePosting SGP / iOptron CEM-60EC Meridian Flip Failure - posted in Mounts: I have another thread going on this enigma. I am posting again to possibly get new ideas as to the ongoing flip failure. I appreciate all the help in the other thread deeply...but it hasnt cured the problem. I am sitting at my pier with a bunch of daylight meridian targets ready to try anything before nightfall. Here is the log from the latest failure (only the flip failure section) and a link here to the oth...
Failure is a part of our life except for the lucky ones but im pretty sure that no one ever did not experience such. Experiencing it was a painful thing yet in the end when everything is already ok we realize that everything happens for a reason and that everything happens for a purpose. we might not know it that that point in time but sooner or later youll find out. Failure is just passing everything will just go as it should be. take time to reflect and discern what to do next time to avoid failure this is only one thing is for sure, through failure we will learn from our mistakes, there will be many things that we discover in our self and that somehow will know that we are strong to accept such pain. In failure there is a opportunity to improve and be better the next time ...
Having battled - unsuccessfully - with full-blown CFS for about 5 years, I hooked up with a good specialist and have managed to pull myself largely out...
After years of unsuccessfully trying to have kids, this womans sister decided to carry her baby for her. Little did they know a miracle had happened.
We take a look at the failure rates of 91,243 hard drives used in the Backblaze data centers in 2017 and compare the performance by manufacturer and model.
Revealed: The Secret of Famous People.Why Failure is Good For Success. It May Not Be The Nicest of Things That Could Ever Happen To You. Yet, Failure is Pivotal to Ones Success. Dont Believe Me? Let me Show You How Failure Turned These Ordinary People Into Extraordinary People.
When you think of forms of market failure, what comes to mind? Have you ever identified a market failure that has affected your job or industry? What about
Its easy to be philosophical about failure when advising someone else, but things look different when youre facing a faux pas, fumble, or f***-up of your own. Let me offer some perspective from a recent experience.
Failure to thrive means that a child is not growing as he or she should. Psychological, social, or economic problems within the family almost always play a role in this condition.
Between Failures is a slice-of-life webcomic following the (somewhat under-motivated and decidedly sarcastic) staff of a chain bookstore created by Jackie Wohlenhaus.
Between Failures is a slice-of-life webcomic following the (somewhat under-motivated and decidedly sarcastic) staff of a chain bookstore created by Jackie Wohlenhaus.
Hello all, its exactly as the title says, I feel like Im doomed to failure. Im 23 and still not entirely certain what I want ...
Sometimes trying your best isnt enough; when the situation demands it, you need to be perfect. Sometimes trying your best isnt enough; when the situation demands it, you need to be perfect. For
I started with Windows XP , Office 2007 and IE.... Firefox was not installed nor ever was. I did install it though to do the HKEY classes root\firefox\ddexec\ regsitry value clearing ideas as found...
Hey all, Some of you may have heard me before but now that I have tried EVERYTHING I know that something is just not right and I need to know if I am Alone...
Ervin, Kathleen A. "The Treatment Trap". Failure Magazine. Retrieved 22 August 2013. Prometheus: "Millions of Americans are ... The Treatment Trap - How the Overuse of Medical Care is Wrecking your Health and what you can do to Prevent it is a 2010 book ... The Treatment Trap: How the Overuse of Medical Care is Wrecking Your Health and What You Can Do to Prevent It" by Rosemary ...
Ali S, Lally EV (November 2009). "Treatment failure gout". Medicine and Health, Rhode Island. 92 (11): 369-71. CiteSeerX 10.1. ... There are several types of medications that are used for the treatment of arthritis. Treatment typically begins with ... Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be ... Treatment options vary depending on the type of arthritis and include physical therapy, exercise and diet, orthopedic bracing, ...
Ali, S; Lally, EV (November 2009). "Treatment failure gout". Medicine and Health, Rhode Island. 92 (11): 369-371. PMID 19999896 ... "Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: ... Without treatment, an acute attack of gout usually resolves in five to seven days; however, 60% of people have a second attack ... Without treatment, episodes of acute gout may develop into chronic gout with destruction of joint surfaces, joint deformity, ...
Ali, S; Lally, EV (November 2009). "Treatment failure gout". Medicine and Health, Rhode Island. 92 (11): 369-71. PMID 19999896 ... Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can ...
Torsney, P.J. (November 1973). "Treatment failure: insect desensitization. Case reports of fatalities". The Journal of Allergy ... Emergency treatment is only needed if a person is showing signs of a severe allergic reaction. Prior to calling for help, stung ... The nature of treatment for a Myrmecia sting depends on the severity of stingose, and the use of antihistamine tablets are ... However, fatal failures were reported, and this led to scientists to research for alternative methods of desensitisation. ...
Bramwell, C. (20 November 1937). "Treatment of heart failure". Br Med J. 2 (4011): 1005-1008. doi:10.1136/bmj.2.4011.1005. PMC ... with A. Morgan Jones: Bramwell, C.; Jones, A. M. (July 1944). "Acute left auricular failure". Br Heart J. 6 (3): 129-134. doi: ... Bramwell, C. (1 June 1935). "Treatment of heart disease in pregnancy". Br Med J. 1 (3882): 1132-1133. doi:10.1136/bmj.1.3882. ...
"Treatment failure in osteoporosis". Osteoporosis International. 23 (12): 2769-2774. doi:10.1007/s00198-012-2093-8. hdl:11343/ ... and offer concrete advantages from the point of view of short-term follow-up of patients undergoing therapeutic treatments. ...
Golden, David B. K. (27 November 1981). "Treatment Failures With Whole-Body Extract Therapy of Insect Sting Allergy". JAMA: The ... Torsney, P.J. (November 1973). "Treatment failure: insect desensitization. Case reports of fatalities". The Journal of Allergy ... Emergency treatment is needed in a case of a severe allergic reaction. Before calling for help, laying a person down and ... Other treatments include washing the stung area with soap and water, and if continuous pain remains for several days, ...
"Government Failure". tutor2u. "Policy Myopia:causes and treatment". VOX Ukraine. • Blanchard, Olivier Jean (2008). "crowding ... However, Government failure often arises from an attempt to solve market failure. The idea of government failure is associated ... As with a market failure, government failure is not a failure to bring a particular or favoured solution into existence but is ... Government failure can be on both the demand side and the supply side. Demand-side failures include preference-revelation ...
Time to treatment > 4 hours? Yes (+1) What Does This Score Mean? Prior heart failure? Yes (+2) History of atrial fibrillation? ... TIMI 10B compared the angiographic efficacy and safety of several doses of TNK with front loaded rtPA for the treatment of ST ... ASSENT I-(TIMI 10C) compared the safety of several doses of TNK-tPA with rtPA for the treatment of ST elevation myocardial ... TIMI 12 evaluated the safety and efficacy of the oral GP IIb/IIa inhibitor sibrafiban for the treatment of patients with a ...
Mortality with treatment is 50%. O'Grady JG, Schalm SW, Williams R (1993). "Acute liver failure: redefining the syndromes". ... a third form of liver failure known as acute-on-chronic liver failure (ACLF) is increasingly being recognized. Acute liver ... Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal ... One scheme defines "acute hepatic failure" as the development of encephalopathy within 26 weeks of the onset of any hepatic ...
The type of treatment depends on the severity of the patient's bone marrow failure disease. Blood transfusion is one treatment ... Bone marrow failure in both children and adults can be either inherited or acquired. Inherited bone marrow failure is often the ... Bone marrow failure occurs in individuals who produce an insufficient amount of red blood cells, white blood cells or platelets ... "Bone Marrow Failure In Children - What You Need to Know". www.drugs.com. Retrieved 2017-01-31. Kitchen, Rose. "Signs & Symptoms ...
Treatment of acute failure depends on the underlying cause. Treatment of chronic failure may include hemodialysis, peritoneal ... Kidney failure can be divided into two categories: acute kidney failure or chronic kidney failure. The type of renal failure is ... Acute failure is often reversible while chronic failure often is not. With appropriate treatment many with chronic disease can ... The treatment of acute kidney injury depends on the cause. The treatment of chronic kidney failure may include renal ...
Ingelfinger, Julie R (16 November 2017). "Diuretic Treatment in Heart Failure". The New England Journal of Medicine. 377 (20): ... For those with underlying renal impairment or severe heart failure, up to 160 to 200 mg bolus dose can be given. Hypertension ... They are primarily used in medicine to treat hypertension and edema often due to congestive heart failure or chronic kidney ... Loop diuretics may also precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor-the so-called ...
Cruickshank JM (2010). "Beta-blockers and heart failure". Indian Heart J. 62 (2): 101-10. PMID 21180298. "Amitriptyline: Side ... Preventive treatments can be sub-divided into non-drug treatments, and treatment with medication. Non-drug treatment, when ... Ditans are a class of abortive medication for the treatment of migraines. Recommended initial treatment for those with mild to ... ONS for the treatment of medically intractable headaches was introduced by Weiner and Reed ONS is typically performed with the ...
... failure to provide medical treatment; verbal, physical and psychological abuse; separation of family members; and dangerous ... In some cases the asylum officers apologized to the migrants for the treatment they had received from the Border Patrol. ... Shear, Michael D.; Rogers, Katie (September 24, 2021). "Biden Condemns Border Patrol Treatment of Haitian Migrants as ... "illegal immigrants deserve the same constitutionally-mandated humane treatment of citizens and legal residents". In 1998, ...
Anand, I. S.; Florea, V. G. (2001). "High Output Cardiac Failure". Current Treatment Options in Cardiovascular Medicine. 3 (2 ... Treatment is by thiamine supplementation, either by mouth or by injection. With treatment, symptoms generally resolve in a few ... In the acute form, the baby develops dyspnea and cyanosis and soon dies of heart failure. These symptoms may be described in ... It is sometimes fatal, as it causes a combination of heart failure and weakening of the capillary walls, which causes the ...
Treatment of HH is usually with hormone replacement therapy, consisting of androgen and estrogen administration in males and ... Syndromes in Organ Failure. 53 (3): 395-405. doi:10.1016/j.cnur.2018.04.006. PMID 30100005. S2CID 51966781. Viswanathan V, ... However, it is important to note that testosterone treatment does not restore fertility in men. There are many infertility ... Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism or primary gonadal failure, is a ...
Treatment depends on severity and case. For people with chronic, stable, mild heart failure, treatment usually consists of ... heart failure/pulmonary hypertension, heart failure/diabetes, heart failure/kidney failure, etc. Whether the problem is ... Heart failure, American Heart Association - information and resources for treating and living with heart failure Heart Failure ... There are different types of heart failure: right-sided heart failure, which affects the right heart, left-sided heart failure ...
Eysenck, Hans J. (1986a). "Failure of treatment - failure of theory?". Behavioral and Brain Sciences. 9 (2): 236. doi:10.1017/ ... He faulted his treatment of The Interpretation of Dreams and The Psychopathology of Everyday Life, arguing that he ignored ... He summarizes its two premises as being that "only the psychoanalytic method of interpretation and treatment can yield or ... He criticized Grünbaum for giving insufficient attention to Freud's use of cocaine and his treatment of Emma Eckstein. The ...
"Improving heart failure treatment through research , BHF". "Charities fined over 'wealth screening' data breaches". BBC News ... 7.5 million over four years to fund scientists looking for new treatments for heart failure. The British Heart Foundation ... They wanted to fund extra research into the causes, diagnosis, treatment, and prevention of heart and circulatory diseases. It ...
... this method is prone to failure. Also, the underlying condition can still become symptomatic if the nail grows back within a ... Surgical treatments of ingrown toenails include a number of different options. If conservative treatment of a minor ingrown ... If the ingrown toenail recurs despite this treatment, destruction of the germinal matrix with phenol is recommended. As an ... Ozdemir, Esin; Bostanci, S; Ermekci, P; Gurgey, E (2004). "Chemical matricectomy with 10% sodium hydroxide for the treatment of ...
"Premature Ovarian Failure, POF Treatment & Diagnosis , IVF Clinic". (Menstrual disorders). ... Resistant ovary syndrome, previously known as Savage syndrome, is a cause of ovarian failure that can lead to secondary ...
... multiple treatment failures...multiple times on probation...served previous jail or prison sentences...driven by their ... Her parents told her that the charges would be dropped if she agreed to check into an out-of-town drug treatment program, away ... Her parents got her into treatment programs several times, but it didn't help. She got a job at a restaurant/bar and started ... The sanctions of the judge are viewed as part of "treatment", not the imposition of a sentence. Judge Williams insisted that ...
Administration of recombinant factor VIIa has shown promise; however, this treatment approach requires further study. The use ... Phrases subfulminant hepatic failure and late onset hepatic failure were coined for onset between 2 weeks to 3 months and for 8 ... Wilson's disease (hereditary copper accumulation) may infrequently present with acute liver failure. Acute liver failure also ... multiorgan failure, sepsis, cardiac arrhythmia or arrest and respiratory failure. The median time to death after admission was ...
These treatments are biologically implausible and the clinical tests have shown they don't do anything at all in human beings. ... hawthorn for congestive heart failure; guar gum for diabetes. In our book More Good Than Harm? ... ethicist Kevin Smith and I ... In a review of Trick or Treatment in the New England Journal of Medicine, Donald Marcus described Ernst as "one of the best ... ISBN 978-0-593-06129-9, 416 pages (The same book published in the US is called Trick or Treatment: The Undeniable Facts about ...
"Heart Failure (Congestive Heart Failure): Symptoms & Treatment". Cleveland Clinic. Retrieved 2022-04-06. "Is It Congestive ... "Heart Failure in Women". Cleveland Clinic. Retrieved 2022-04-06. "Heart Attack: What Is It, Causes, Symptoms & Treatment". ... Congestive heart failure (CHF) is where the heart muscle is unable to pump blood efficiently or at its normal capacity, ... Because of the location of the heart in relation to the breasts, breast cancer treatments have shown to cause the increased ...
Leonidas and Eudoxia Mamas report six cases of premature ovarian failure. After two to six months of treatment with DHEA (Two ... This treatment protocol has also reversed some cases of iatrogenic POF caused by full body radiation treatment. While the ... Variable success rate with treatment, very few controlled studies, mostly case reports. Treatment success strongly tends to ... "Successful pregnancies after combined pentoxifylline-tocopherol treatment in women with premature ovarian failure who are ...
The STICH trial (Surgical Treatment for IschemiC Heart Failure) will examine the role of medical treatment, coronary artery ... CCM is particularly suitable for the treatment of heart failure patients with normal QRS complex duration (120 ms or less) and ... Newly emerging evidence showed that glucocorticoids could be used in the treatment of decompensated heart failure to potentiate ... December 2007). "The rationale and design of the Surgical Treatment for Ischemic Heart Failure (STICH) trial". J. Thorac. ...
Heart failure drug treatment: the fantastic four. Dr. Johann Bauersachs was awarded the Oskar-Lapp Award (2001) and the Albert- ... Bauersachs, Johann (2021-02-11). "Heart failure drug treatment: the fantastic four". European Heart Journal. 42 (6): 681-683. ... A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology". ... A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology". ...
... relating to the treatment of slaves. 1836. pp. 32-35. Stone, Asa A. (1836). "The General Treatment of Slaves at the South-west ... "Such an institution would undoubtedly attract many of Weld's associates who had been disappointed in the failure to establish ... They were subject to discriminatory treatment in everyday life. The original "remedy" for this problem was to help them go " ... relating to the treatment of slaves. pp. 15-32. Getz, Lynne Marie (2006). "Partners in Motion: Gender, Migration, and Reform in ...
Chelsea's failure to clear the loose ball gave Michael Carrick the chance to extend his side's lead, but Čech was again equal ... resulting in both players being booked and Scholes having to leave the field for treatment to a bloody nose. The first goal of ...
The construction of a provincially-funded $101 million mental health and addiction treatment facility on the Riverview grounds ... would commit suicide shortly after discharge due to failure to properly medicate from lack of professional supervision. Andrew ... Regional clinics began drawing patients from Riverview, and both advances in treatment and eventual cutbacks in funding ... 218 staff FTEs for case management/outpatient treatment duties, resulting in 4,360 additional units of care being available to ...
... when he warns of the likelihood of brutal treatment by the authorities. On the day of the meeting, thousands of people march ... "Peterloo marks a rare failure for Film4". Sharpe's Justice "Peterloo". Venice International Film Festival 2018. Venice Biennale ...
Heavey, Susan; White, Lawrence; Roantree, Anne Marie (26 August 2020). "U.S. slams HSBC over treatment of Hong Kong customers, ... Lai attributed this business failure to overconfidence and a lack of viable business strategy. In 2011, Next Media reportedly ...
Consequently, inhibiting PTGS2 (COX-2) may have benefit in the prevention and treatment of these types of cancer. COX-2 ... such as heart failure, myocardial infarction, and stroke. Studies with human pharmacology and genetics, genetically manipulated ... EntrezGene 5743 Menter DG, Schilsky RL, DuBois RN (March 2010). "Cyclooxygenase-2 and cancer treatment: understanding the risk ...
I want to say in the most forceful way I can: I certainly hope so." In the wake of the Lincoln failure, former FHLBB chair Gray ... Fred Wertheimer, president of Common Cause, which had initially demanded the investigation, thought the treatment of the ... The U.S. savings and loan crisis of the 1980s and early 1990s was the failure of 747 savings and loan associations in the ... Gives best explanation for House treatment of Keating reimbursements. Carlson, Margaret (1991-03-11). "Then There Was One". ...
... they may reject medical treatment and advice, especially, they may reject less-critical wellness treatments such as birth ... looked to the US for guidance and were not willing to arm the enemies of the US with more propaganda about its failures in ...
His lack of influential allies in Whitehall led to the failure of this mission.[citation needed] At this time, many members of ... more than a bourgeois commercialism tricked out in shallow utilitarian moralisms and Owen Aldridge's sympathetic 1967 treatment ...
... "inhuman and degrading treatment". In 2006 the court decided that Article 3 of the European Convention on Human Rights ( ... where he attended a meeting of senior PFLP officials to justify his failure to execute two senior OPEC hostages - the finance ... prohibition of inhuman and degrading treatment) had not been violated; however, Article 13 (right to an effective remedy) had ...
The INC, which has received bad, and in some cases malicious treatment, from the State Department and intelligence community ... The Anatomy of Failure in War, Free Press, 1990, ISBN 0-02-906060-5. With Thomas A. Keaney, Gulf War Air Power Survey Summary ...
No person may be tried in absence, unless the court is satisfied that the charged person's failure to attend the trial is ... freedom from cruel or degrading treatment. All forms of physical, mental, and emotional torture are prohibited, as are "cruel, ... nobody may be subjected to scientific or medical treatment without informed consent, or the consent of a lawful guardian. ... inhumane, degrading or disproportionately severe treatment or punishment." Similarly, ...
Rajagopalachari, C. V. Failure of Gandhism and Communism. C.V. Rajagopalachari, 1972. Ward, Gabriele Ebert ; foreword by Alan ... Guruswami Mudaliar never treated anyone for free as he believed free treatment would be deemed valueless. He charged a very ... However, many city doctors were highly critical of Mudaliar for prescribing a branded tablet as treatment which they felt ... he kept his left hand on her back and began his percussion treatment. Suddenly he stopped at one spot and taking out a copying ...
Common problems among the other browsers included the failure to properly render the URLs in the tab title bar and failing to ... For this reason, the UASG commissioned a report on the performance of major browsers in the treatment and acceptance of 17 ...
In most schools targeted, a ban on beating students for wrongdoings or failure has been enforced. In one case, flogging of ... Inhuman or Degrading Treatment or Punishment, and the Convention on the Rights of the Child. The 2003 peace agreement that ... and that the failure of Sirleaf to deal with this issue has led to "the perception that the president lacks the will to address ... Inhuman or Degrading Treatment or Punishment. New York, 10 December 1984". Archived from the original on 8 November 2010. ...
Though these games are anti-violent, however, failure on the part of the player leads to violence. Thus the goal of the game is ... Gender-marketers have designed strategy games for both male and female audiences, however gender-linked treatment of violence ...
These benefits not only include tax-free cash payments but can also include free or low-cost mental health treatment and other ... Failure to Adopt the Federal Rules of Evidence Allows the VA to Rely on Incompetent Examiners and Inadequate Medical ... change VA disability benefits for PTSD include urging the VA to place more emphasis on vocational rehabilitation and treatment ...
This is primarily caused by instantaneous kidney failure, liver failure, and failure of various other organs.[dubious - discuss ... field measurements in wastewater treatment plants, surface waters, and lake sediments". Environ Sci Technol. 36 (23): 4998-5004 ...
Treatment centres around the symptoms. The intestinal atresia is usually surgically correctable in infancy with anastomosis. ... A 2021 case report reported the successful use of a kidney transplant for renal failure in one late adolescent patient. The ... Treatment targets the symptoms. The intestinal atresia is usually surgically correctable in infancy with anastomosis; however, ... Although one was found to have normal kidneys on examination at birth, he later developed kidney failure in late adolescence ...
He is not counted among the traditional seven, and theologians of their religions are ambivalent in their treatment of him. At ... Rhodar (deceased by obesity and heart failure): King of Drasnia, husband of Porenn, father of Kheva, and uncle of Silk. Porenn ...
Two wins at Snetterton helped him to close the gap on Giovanardi, but a mechanical failure in race 3 was a precursor to a ... He was taken from the scene by former BTCC driver Phil Bennett and after treatment at three hospitals, including Stoke ...
experienced a failure of an LNG tank. 128 people perished in the explosion and fire. The tank did not have a dike retaining ... The process begins with the pre-treatment of a feedstock of natural gas entering the system to remove impurities such as H2S, ... Failure to remove much or all of such acidic molecules, mercury, and other impurities could result in damage to the equipment. ...
The treatment is dependent on the severity of respiratory impairment and the underlying etiology of the disorder. In most cases ... Bilateral pulmonary agenesis is highly rare and it is caused by the complete failure in the development of respiratory ... If the defect is extensive but there is a chance for the fetus to live, an exo-utero intrapartum treatment (EXIT) may be ... The main focus of the treatment procedure is to preserve the remaining functional tissue and prevent significant ...
... the Enron scandal undoubtedly is the biggest audit failure causing the dissolution of Arthur Andersen, which at the time was ... "the researcher gathered by administering treatments to subjects"; analytical research, which is "based on the act of formally ...
Another common drug treatment is the alpha-agonist midodrine. Non-drug treatments include "head-up tilt" (elevating the head of ... MSA is also different from multiple organ dysfunction syndrome, sometimes referred to as multiple organ failure, and from ... Bensimon G, Ludolph A, Agid Y, Vidailhet M, Payan C, Leigh PN (January 2009). "Riluzole treatment, survival and diagnostic ... Hardy J (2008). "Multiple system atrophy: pathophysiology, treatment and nursing care". Nursing Standard. 22 (22): 50-6, quiz ...
The other most common categories of malpractice include negligent treatment and failure to warn. Thus, when a patient claims ... Failure to warn: a medical professional is alleged to have treated the patient without first warning the patient of known risks ... Negligent treatment: a medical professional is alleged to have made a mistake that a reasonably competent professional in the ... A duty was owed: a legal duty exists whenever a hospital or health care provider undertakes care or treatment of a patient. A ...
... who were unwilling to wait for tests to determine if current treatments were effective, or discard treatments if they were ... An Anatomy of Failure, A Blueprint for the Future. Springer Science+Business Media. pp. 102. ISBN 978-1-4020-8620-5. Porter TM ... Louis acknowledged his own research included too few cases for absolute certainty in the treatment methods, and his student ... He eventually wrote studies on the treatment of tuberculosis and typhoid fever, and produced the "numerical method" for ...
... such as component failure and general wear and tear, should not be considered "extraordinary circumstances"". Therefore, ... British courts may deviate from these previous rulings under the same principles that guide their treatment of earlier ...
A Colombian Air Force CASA CN-235 carrying Colombian military personnel suffers engine failure and crashes at Codazzi, Colombia ... and a water treatment plant in Syria since the Russian intervention there began on 30 September. 2 December A U.S. airstrike in ... Raghavan, Sudarsan, "U.S. cites errors and technical failures in report on Afghan hospital attack," washingtonpost.com, 25 ... "Another major rocket failure for a space industry out to prove itself," washingtonpost.com, 28 June 2015, 8:05 p.m. EDT. Quiano ...
His childhood was marred by the failure of his parents' marriage and his father's business. Originally staying with his father ... Visiting cattle stations and private properties to give medical treatment, Michod was aware of the difficulties faced in the ...
Table 2. Comorbid Conditions Most Strongly Associated With Treatment Failure Comorbid Condition Odds Ratio 95% Confidence ... Table 1. Follow-up Required After Treatment Failure for Community-Acquired Pneumonia ... Treatment for community-acquired pneumonia was more likely to fail if patients had at least one other medical condition. ... It is important to get national data on antibiotic failure, but "you cant make guidelines based on the national database," Dr ...
Evaluation of factors associated with failure of tuberculosis treatment under DOTS in northern Islamic Republic of Iran  ... ART failure and strategies for switching ART regimens in the WHO European Region : report of the WHO expert consultation, ... ART failure and strategies for switching ART regimens in the WHO European Region: report of the WHO expert consultation: ... The value of treatment: early intervention to reduce the burden of brain disorders  ...
Evaluation of factors associated with failure of tuberculosis treatment under DOTS in northern Islamic Republic of Iran  ... ART failure and strategies for switching ART regimens in the WHO European Region : report of the WHO expert consultation, ... ART failure and strategies for switching ART regimens in the WHO European Region: report of the WHO expert consultation: ... The value of treatment: early intervention to reduce the burden of brain disorders  ...
Treatment failure was well documented in three patients with ulcers (two penile and one oral). After treatment of each patient ... This report describes the use of azithromycin for syphilis treatment, recent treatment failures in San Francisco, and CDC ... In April 2003, SFDPH became aware of an azithromycin failure in the treatment of primary syphilis in one patient and ... Brief Report: Azithromycin Treatment Failures in Syphilis Infections --- San Francisco, California, 2002--2003. ...
Decompensated heart failure is severe heart failure that requires immediate medical attention. Symptoms include breathlessness ... Treatment. Decompensated heart failure treatment helps stabilize symptoms and protect kidney function. Treatment will depend on ... Acute decompensated heart failure. Acute decompensated heart failure is the most common form of acute heart failure and occurs ... Heart failure during pregnancy. A 2016 article mentions diuretics as the first treatment the medical community recommends for ...
This study provides valuable information on treatment patterns after an initial hospitalization for HF. ... Pharmacological treatment patterns in heart failure: a population-based cohort study Eur J Clin Pharmacol. 2020 Jan;76(1):97- ... Objectives: To describe the treatment initiation patterns and the subsequent treatment changes among HF patients, in the first ... During the follow-up, 24.4% died, 20% were not exposed to any HF treatment, 48.3 to 43.2% had diuretics, one third had BB or ...
Are you aware of the latest research into diabetes treatment failure, including the ability of medications other than metformin ... Are you aware of the latest research into diabetes treatment failure, including predictors of metformin monotherapy efficacy ... Cite this: Rapid Review Quiz: Type 2 Diabetes Treatment Failure - Medscape - Apr 12, 2023. ... Metformin is not the only treatment for T2D, but the importance of finding treatment that works is essential. ...
Johns Hopkins scientists shed light on different forms of heart failure seen in men and women that may require the development ... Men, Women may Need Gender-Specific Heart Failure Treatment Personalised Printable Document (PDF). Please complete this form ... 23-Year-Old With End Stage Heart Failure Gets a New Lease of Life After a Heart Transplant. Doctors had no other go than heart ... Higher Level of Physical Activity Lowers the Risk of Developing Heart Failure. Walking 30 minutes a day might not be enough for ...
Acute renal failure results from physical damage to the kidneys, blood loss or toxins. Reviewed by a board-certified internal ... Treatment The treatment of acute renal failure depends on the cause of the problem, as well as the severity of the situation. ... Stopping the use of toxins: If acute renal failure is caused by a medication or supplement, the treatment should include ... Many people improve with treatment and do not experience long-term problems or chronic renal failure. ...
Increased thirst is often the first sign of kidney failure in cats. ... Chronic Renal Failure in cats also known as Kidney disease. ... Treatment of Chronic Renal Failure. Chronic kidney failure is ... This is the least intrusive and most beneficial treatment you can give your cat. Cats in chronic renal failure drink a lot of ... Kidney disease, in the form of chronic renal failure (CRF), is a common problem in older cats. I have seen kidney failure in ...
Our experts offer personalized care plans for patients with congestive heart failure, offering medications, therapy, education ... Heart failure treatment program in San Antonio. At Methodist Healthcare, we offer a heart failure program that provides medical ... Heart failure treatment. With the information received from your tests, your doctor will determine the appropriate treatment ... In the case of advanced heart failure, inpatient treatment includes intravenous medications. Mostly, heart failure is a chronic ...
... and therapies which reduce mortality in people with heart failure and reduced ejection fraction (HFrE ... Treatment is even more challenging in people with heart failure and preserved ejection fraction (HFpEF), with currently no ... Are SGLT-2 Inhibitors the Future of Heart Failure Treatment? The EMPEROR-Preserved and EMPEROR-Reduced Trials. *David M. ... Williams, D.M., Evans, M. Are SGLT-2 Inhibitors the Future of Heart Failure Treatment? The EMPEROR-Preserved and EMPEROR- ...
... experienced reduced rates of treatment failure when adding azithromycin to their standard of care. ... was reduced treatment failure compared with standard of care alone. Rates of treatment failure were under 50% for patients ... Azithromycin May Reduce Treatment Failure in Patients With Acute Exacerbation of COPD. ... which found that the antibiotic can reduce treatment failure in patients hospitalized with acute exacerbation of the disease. ...
Know all possible symptoms and book an online appointment for liver failure. ... Get liver failure treatment at Max Hospital in Delhi NCR. ... Liver Failure Treatment If detected early enough, acute liver ... Liver Failure Symptoms The initial symptoms of liver failure can be due to many conditions. Because of this, liver failure may ... More commonly, liver failure develops slowly over the course of years. But in acute liver failure, liver failure develops in a ...
Heart Failure: Treatment. Piedmont Augustas Advanced Heart Failure Center. 1350 Walton Way. Augusta, GA 30901-2629. Phone: ... home / services / heart and vascular / hvi clinics and centers / heart failure and lvad / treatment ... You may get palliative care when heart failure is diagnosed, throughout treatment, during follow-up, and at the end of life. ... Learn more about Piedmont Augustas LVAD Treatment. Lifestyle Changes. Up to half of patients hospitalized for heart failure ...
Heart Failure News Article Heart Failure Treatment Guidelines 2013. June 05, 2013. CardioSmart News ... While you are feeling well, it is important to think about what treatments you would want if your heart failure were to worsen ... Knowing the type of heart failure you have will help your doctor select the best treatment for you. ... Your Treatment Plan. To keep you healthy your doctor may recommend:. Medications to improve your hearts function and prevent ...
Learn where to get help paying for kidney failure care and medicine. Read about Medicare coverage, private health insurance, ... Learn key terms about kidney failure costs, insurance, and financial aid.. Kidney failure treatment is costly, but there are ... You may also be able to get help paying for your kidney failure treatment from one or more programs that are run jointly by the ... Kidney failure treatment-hemodialysis, peritoneal dialysis, and kidney transplantation-is expensive. Many people with kidney ...
Tag Archive: treatment failure. CBC TV, Ottawa : Lyme Disease advocate calls for stronger treatment Advocates for people with ...
Care and treatments for people with kidney failure. If you have been told that you have advanced kidney disease or end-stage ... between different treatment centres in the proportion of patients receiving different types of treatment for kidney failure. ... This type of treatment does not replace the work of the kidneys. You may be at a stage in your life where you feel that the ... This type of treatment aims to manage the symptoms of your kidney disease and keep your kidneys working for as long as possible ...
Artificial intelligence-enhanced ECGs may speed heart failure diagnosis and treatment. Circulation: Arrhythmia and ... newsroom.heart.org/news/artificial-intelligence-enhanced-ecgs-may-speed-heart-failure-diagnosis-and-treatment?preview= ... These biomarkers are elevated in the blood when heart failure is present. However, these biomarker levels are also affected by ... "An abnormal ECG raises concern about underlying cardiac abnormalities but are not specific for heart failure," Adedinsewo said. ...
Robustness of Male Treatment Failure with I-131 in Hyperthyroidism Message Subject (Your Name) has sent you a message from ... Robustness of Male Treatment Failure with I-131 in Hyperthyroidism. Megan Zare, David Lewis and Michael Richardson ... Conclusions The results of our series indicate that men have a higher likelihood of treatment failure following radioiodine ... Therefore, identifying factors leading to variable outcomes are of utmost importance to reduce treatment failure. Prior studies ...
Contemporary Heart Failure Treatment Based on Improved Knowledge and Personalized Care of Comorbidities: 10.4018/978-1-5225- ... "Contemporary Heart Failure Treatment Based on Improved Knowledge and Personalized Care of Comorbidities." Healthcare Policy and ... "Contemporary Heart Failure Treatment Based on Improved Knowledge and Personalized Care of Comorbidities." In Healthcare Policy ... Contemporary Heart Failure Treatment Based on Improved Knowledge and Personalized Care of Comorbidities. Kostas Giokas ( ...
If the heart remains weak with standard heart failure treatments, advanced treatment options for severe heart failure include ... Another advanced treatment for severe heart failure is a heart transplant. If you have advanced heart failure, your surgeon ... Please watch the entire video to learn about the surgeries for heart failure. Surgeries for advanced heart failure include ... This video will help you understand the main surgical procedures done to treat heart failure. ...
Conversion to THA: A Treatment Path or a Treatment Failure?. Hip Preservation in 2021 - Can We Prevent Hip Arthritis Across the ... Home / 2021 Congress / Conversion to THA: A Treatment Path or a Treatment Failure? ...
Treatment with 75 nM of ixazomib for 24 hours is associated with markedly increased apoptosis, as shown by a representative ... Our results underscore the importance of FOXM1 in AML progression and treatment, and they suggest that targeting it may have ... Acute myeloid leukemia (AML) patients with NPM1 mutations demonstrate a superior response to standard chemotherapy treatment. ... following 24-hour treatment in liquid culture, as assessed by quantitative PCR. Data are expressed as the mean ± SEM (. n. = 11 ...
Treatment of intestinal failure: intestinal transplantation. Journal Article (Journal Article;Review) Over the past 15 years, ... intestinal transplantation for the treatment of intestinal failure has changed from a desperate last-ditch effort into a ...
... treatment from the Merck Manuals - Medical Consumer Version. ... Drug Treatment for Heart Failure - Learn about the causes, ... In systolic heart failure (heart failure with reduced ejection fraction Types of heart failure Heart failure is a disorder in ... In diastolic heart failure (heart failure with preserved ejection fraction Types of heart failure Heart failure is a disorder ... Heart failure Heart Failure (HF) Heart failure is a disorder in which the heart is unable to keep up with the demands of the ...
Treatment of severe heart failure: quantity or quality of life? A trial of enoximone. Enoximone Investigators. ... Treatment of severe heart failure: quantity or quality of life? A trial of enoximone. Enoximone Investigators. ...
  • Congestive heart failure (CHF) occurs when excess fluid starts to leak into the lungs and/or other surrounding parts of the body. (sahealth.com)
  • The heart will go into congestive failure as it attempts to compensate for the inadequate number of circulating red blood cells. (sahealth.com)
  • Low-frequency blood flow oscillations in congestive heart failure and after β1-blockade treatment. (lancs.ac.uk)
  • Laser Doppler flowmetry (LDF) of forearm skin blood flow, combined with iontophoretically-administered acetylcholine and sodium nitroprusside and wavelet spectral analysis, was used for noninvasive evaluation of endothelial function in 17 patients newly diagnosed withNewYork Heart Association class II-III congestive heart failure (CHF). (lancs.ac.uk)
  • Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive heart failure secondary to myxomatous mitral valve disease. (umassmed.edu)
  • Acute decompensated congestive heart failure is a condition in which chronic heart failure rapidly becomes worse. (healthguideinfo.com)
  • Congestive heart failure is a major public health issue, and a leading cause of hospitalization in people over the age of 65. (healthguideinfo.com)
  • Beta blockers are often part of the treatment regime for someone who is hospitalized after a heart attack, or for treatment of acute decompensated congestive heart failure. (healthguideinfo.com)
  • Overview of Acutely Decompensated Congestive Heart Failure (ADHF): A Report from the ADHERE Registry. (healthguideinfo.com)
  • Increasing body mass index, neck circumference, Epworth Sleepiness Scale score, hypertension, congestive heart failure, and type 2 diabetes correlated with increasing OSA severity. (cdc.gov)
  • Heart failure-also known as congestive heart failure, or CHF-is a chronic but manageable condition that affects nearly 6 million Americans. (hopkinsmedicine.org)
  • A leaky heart valve , whether in humans or dogs, is one of the first signs that congestive heart failure may be imminent if corrective action isn't taken. (vetinfo.com)
  • This process is called congestive heart failure. (vetinfo.com)
  • This medicine is also used in the treatment of angina and congestive heart failure. (internationaldrugmart.com)
  • The strategy entails associated with a 10-fold increase in the regular daily observation of the treatment in occurrence of poor treatment outcomes the first 2 months in the initial phase. (who.int)
  • Previous cardiovascular outcome trials for sodium-glucose co-transporter-2 (SGLT-2) inhibitors have demonstrated significant favourable outcomes for cardiovascular disease, heart failure hospitalisation and all-cause mortality. (springer.com)
  • The aim of the nearly completed EMPEROR-preserved and EMPEROR-reduced trials is to determine the impact of empagliflozin on cardiovascular and heart failure outcomes in people with HFpEF or HFrEF with or without diabetes. (springer.com)
  • Cardiovascular outcome trials have shown considerable improvement in heart failure hospitalisation and other cardiovascular outcomes in people using sodium-glucose co-transporter-2 (SGLT-2) inhibitors. (springer.com)
  • People with diabetes and heart failure have poorer clinical outcomes, thought to be a consequence of greater cardiovascular risk factors and poor glycaemic control [ 5 ]. (springer.com)
  • Therefore, identifying factors leading to variable outcomes are of utmost importance to reduce treatment failure. (snmjournals.org)
  • A univariable logistic regression analysis was performed, followed by a multivariable regression analysis for significant outcomes between groups on univariable analysis, to determine risk factors for treatment failure. (cam.ac.uk)
  • We now need to kickstart clinical trials in patients with COVID-19 to see if these drugs can improve outcomes and help people overcome their diagnosis more quickly and without the need for more intensive treatment. (timesnownews.com)
  • The recent publication on Carillon in the European Journal of Heart Failure - Treating symptoms and reversing remodelling: clinical and echocardiographic 1-year outcomes with percutaneous mitral annuloplasty for mild to moderate secondary mitral regurgitation - was particularly enlightening. (cardiacdimensions.com)
  • Paraendodontic surgery comprehends a set of procedures recommended in periapical diseases treatment, when traditional endodontic therapy does not obtain favorable outcomes. (bvsalud.org)
  • Using incident reports to assess communication failures and patient outcomes. (ahrq.gov)
  • The treatment of TB using a cocktail of drugs over a period of six months under the directly observed treatment short-course strategy has led to a reduction in cases but is plagued by some challenges that leads to unsuccessful or poor outcomes, which can ultimately result in spread of infections, development of drug resistance and increase in morbidity and mortality. (who.int)
  • The objectives of this study are to determine outcomes of TB treatment in Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria and the factors that may be associated with the outcomes. (who.int)
  • Data from TB registers including demographic and relevant clinical information, and treatment outcomes, were extracted into a structured data extraction format, and analysed with SPSS version 21.0 software package. (who.int)
  • Eight hundred and seven (61.5%) patients had successful treatment, and 34% (n=446) had unsuccessful outcomes made of `loss to follow-up' 25.8% (n=339), deaths 7.8% (n=102) and treatment failure 0.4% (n=5), while 2.3% (n=30) were transferred out and 2.3% (n=30) removed from TB register. (who.int)
  • High rates of `loss to follow- up' and deaths in this study is a wake-up call to all stakeholders in the facility and the State to put in place measures to reduce poor outcomes of TB treatment. (who.int)
  • We develop new diagnostic tools, research treatments and track outcomes. (uclahealth.org)
  • Outcomes analysed in the research were overall survival, transplant failure, risk of infections and rebound in HIV viral load. (aidsmap.com)
  • S2 Episode 3: Psychiatric Comorbidities and Schizophrenia Drs John M. Kane and Christoph U. Correll discuss the importance of ongoing assessment of psychiatric comorbidities in patients with schizophrenia and its impact on outcomes and treatment decisions. (medscape.com)
  • Decompensated chronic heart failure affects individuals who already have a diagnosis of heart failure. (medicalnewstoday.com)
  • Once European Commission approves Entresto, it will be available for the treatment of adult patients with symptomatic chronic reduced ejection fraction (HFrEF). (medindia.net)
  • Kidney disease, in the form of chronic renal failure (CRF), is a common problem in older cats. (catsofaustralia.com)
  • Long-term feeding of an all-dry-food diet is also suspected as a factor in Chronic Renal Failure. (catsofaustralia.com)
  • Chronic kidney failure is progressive and incurable. (catsofaustralia.com)
  • Diabetes increases the risk of developing heart failure by more than twofold in men and fivefold in women, with an estimated 25% of people with diabetes suffering chronic heart failure [ 3 ]. (springer.com)
  • A randomized controlled trial found that patients hospitalized for an acute exacerbation of chronic obstructive poulmonary disease (COPD) experienced reduced rates of treatment failure when adding azithromycin to their standard of care. (ajmc.com)
  • Azithromycin may offer relief for patients with chronic obstructive pulmonary disease (COPD), according to a randomized controlled trial, which found that the antibiotic can reduce treatment failure in patients hospitalized with acute exacerbation of the disease. (ajmc.com)
  • New perspectives in the treatment of chronic heart failure. (bvsalud.org)
  • Dr. Heyka's specialty interests include chronic and acute renal failure, dialysis, hypertension, renal bone disease, cardiovascular disease in kidney patients, and vascular access for dialysis. (clevelandclinic.org)
  • Having this treatment available for some patients provides an alternative for managing this chronic condition," said Farley. (medscape.com)
  • However, a recent analysis of healthcare records in the United States found that more than 40% of patients experienced some degree of metformin failure. (medscape.com)
  • At Methodist Healthcare, we offer a heart failure program that provides medical and surgical therapies for heart failure, including optimal medication management, infusion therapy, mechanical assistive devices and heart transplantation. (sahealth.com)
  • For more information about our heart failure program, please call Methodist Healthcare HealthLine at (210) 575-0355 . (sahealth.com)
  • Find out what patients have to say about their treatment, recovery, and overall experience at Max Healthcare. (maxhealthcare.in)
  • Improvements in treatment at the onset of symptoms could have a great benefit on easing the burdens on healthcare systems globally. (timesnownews.com)
  • All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. (ehealthme.com)
  • healthcare providers can order Chagas disease treatment drugs for their patients directly from pharmacies instead of going through CDC. (cdc.gov)
  • In these cases, children can be fed intravenously via a process called parenteral nutrition, however this is associated with severe complications such as line infections and liver failure. (technologynetworks.com)
  • Fracture Related Infections and Their Risk Factors for Treatment Failure-A Major Trauma Centre Perspective. (cam.ac.uk)
  • Risk Factors for Treatment Failure in Skin and Soft Tissue Infections Caused by Nontuberculous Mycobacteria. (bvsalud.org)
  • This study investigated the characteristics of patients with skin and soft tissue infections (SSTIs) caused by nontuberculous mycobacteria (NTM) and identified the risk factors for treatment failure in these patients . (bvsalud.org)
  • Six patients had recurrent infections (13%) after the treatment course was completed, and 3 patients (6.4%) died of NTM-related infection . (bvsalud.org)
  • Unfortunately, 14 patients did not clear their infections, meaning that they did not get cured for malaria using this three day dihydroartemisinin-piperaquine treatment. (cdc.gov)
  • This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)
  • The symptoms of acute renal failure occur because these substances accumulate in the body when the kidney does not work the way it should. (verywellhealth.com)
  • Acute kidney failure can be temporary or may be the sign of a larger problem. (verywellhealth.com)
  • This describes causes of kidney failure that begin before blood reaches the kidneys. (verywellhealth.com)
  • I have seen kidney failure in cats as young as 4 years, but far more frequently in much older cats. (catsofaustralia.com)
  • The kidneys have a very large reserve capacity, and symptoms of kidney failure are not seen until approximately 75% of kidney tissue is non-functional. (catsofaustralia.com)
  • In my experience, kidney failure is the most common cause of death in older cats. (catsofaustralia.com)
  • A cat with kidney disease or kidney failure should not be vaccinated at all. (catsofaustralia.com)
  • No conventional or alternative medical treatment can reverse its course, since the disease involves the loss of kidney cells and replacement by scar tissue. (catsofaustralia.com)
  • You may have heard that restricting protein is recommended for cats in kidney failure. (catsofaustralia.com)
  • Restricted protein does not prevent kidney failure in a healthy cat. (catsofaustralia.com)
  • What is Kidney Failure? (nih.gov)
  • Kidney failure treatment - hemodialysis , peritoneal dialysis , and kidney transplantation -is expensive. (nih.gov)
  • Many people with kidney failure need help paying for their care. (nih.gov)
  • For many people with kidney failure, the Federal Government-through Medicare -helps pay for much of the cost of their treatment. (nih.gov)
  • The U.S. Congress passed the Social Security Amendments of 1972 that guarantee Medicare coverage for most people with kidney failure-even those under age 65. (nih.gov)
  • You can also find financial help for kidney failure treatment from other sources, such as joint federal-state programs , private health insurance , private organizations , and medication assistance programs . (nih.gov)
  • You can live for years with kidney failure, so it's important that you get help to pay for your treatment. (nih.gov)
  • Learn key terms about kidney failure costs, insurance, and financial aid. (nih.gov)
  • Kidney failure treatment is costly, but there are many ways to get help paying for your care. (nih.gov)
  • How can I get Medicare for kidney failure? (nih.gov)
  • Most people with kidney failure are not allowed to join a Medicare Advantage plan. (nih.gov)
  • If kidney failure is the only reason you are signing up for Medicare, your Medicare start date will depend on the type of kidney failure treatment you receive. (nih.gov)
  • If kidney failure is the only reason you have Medicare, your coverage end date will depend on whether you had a kidney transplant or dialysis treatment. (nih.gov)
  • Where can I get more information about Medicare's kidney failure treatment coverage? (nih.gov)
  • If you have been told that you have advanced kidney disease or end-stage kidney failure you may have been advised to start thinking about how you would like your kidney disease managed in the future. (kidneyresearchuk.org)
  • This type of treatment aims to manage the symptoms of your kidney disease and keep your kidneys working for as long as possible, but without kidney replacement therapy. (kidneyresearchuk.org)
  • Haemodialysis can be done at a kidney unit or in your own home and usually involves at least three four-hour sessions of treatment each week. (kidneyresearchuk.org)
  • Kidney transplant operations and the treatment required to prevent rejection of the kidney transplant involve risks, and kidneys from donors who have died are in short supply, so you will be asked to have tests to assess your suitability for a transplant. (kidneyresearchuk.org)
  • It can be extremely daunting to consider such major decisions but your kidney doctor or nurse will be on hand to explain the treatments available to you and help you to plan. (kidneyresearchuk.org)
  • It has been specially developed to give clear information about the types of treatments generally available to people with kidney failure, particularly on the choice of different types of dialysis. (kidneyresearchuk.org)
  • However, these biomarker levels are also affected by obesity, age, kidney disease, severe infection, high blood pressure in the vessels that bring blood to the lungs (pulmonary hypertension), abnormal heart rhythms and a specific heart failure medication. (heart.org)
  • Acute kidney failure is the rapid (less than 2 days) loss of your kidneys' ability to remove waste and help balance fluids and electrolytes in your body. (medlineplus.gov)
  • Other blood tests may be done to find the underlying cause of kidney failure. (medlineplus.gov)
  • Contact your provider if your urine output slows or stops or you have other symptoms of acute kidney failure. (medlineplus.gov)
  • 10 mo old pup with kidney failure. (pets.ca)
  • In 1995, approximately 27,900 people initiated treatment for end-stage renal disease (kidney failure) because of diabetes. (coastalcourier.com)
  • Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid condition. (who.int)
  • According to the American Diabetes Association (ADA), metformin monotherapy is the first-line treatment for most patients recently diagnosed with type 2 diabetes (T2D). (medscape.com)
  • Are you aware of the latest research into diabetes treatment failure, including predictors of metformin monotherapy efficacy and the ability of other medications to lower glucose? (medscape.com)
  • Cite this: Rapid Review Quiz: Type 2 Diabetes Treatment Failure - Medscape - Apr 12, 2023. (medscape.com)
  • Heart failure is frequently associated with diabetes, and therapies which reduce mortality in people with heart failure and reduced ejection fraction (HFrEF) are often limited to drugs which modulate the renin-angiotensin-aldosterone system or heart rate control and occasionally to device therapy. (springer.com)
  • Contrariwise, in one study 45.5% of people with heart failure and preserved ejection fraction (HFpEF) and 41.8% with heart failure and reduced ejection fraction (HFrEF) were diagnosed with diabetes, respectively [ 4 ]. (springer.com)
  • Indeed, the CHARM programme investigators reported that diabetes was an independent predictor of morbidity and mortality in people with heart failure and that the relative risk of cardiovascular death or hospitalisation for heart failure (HHF) associated with diabetes was greater in participants with HFpEF than HFrEF [ 7 ]. (springer.com)
  • As a result, superior treatments for heart failure, particularly in patients with HFpEF with underlying diabetes, are needed. (springer.com)
  • Given that FRI treatment in 24 patients (23.5%) ended up in failure, future management need to take into account the predictive variables analysed in this study, redirect efforts to improve management and incorporate adjuvant technologies for patients at higher risk of failure, and implement a multidisciplinary team approach to optimise risk factors such as diabetes and obesity. (cam.ac.uk)
  • Background Coexistent heart failure (HF) and diabetes mellitus (DM) are associated with marked morbidity and mortality. (bmj.com)
  • In addition to their utility in the treatment of CHF, beta blockers are also often used to treat cardiac problems due to vascular disease, coronary artery disease, high blood pressure, and diabetes. (healthguideinfo.com)
  • The guidelines point out the treatment of comorbidities like diabetes, iron deficiency or tumors . (bvsalud.org)
  • Health care and other costs directly related to diabetes treatment, as well as the costs of lost productivity, run $98 billion annually. (coastalcourier.com)
  • This was a randomized, double-blind, placebo-controlled, Phase 2/3 trial to evaluate the safety and efficacy of dociparsat sodium in adults patients with severe COVID-19 who were at high risk of respiratory failure. (clinicaltrials.gov)
  • Age is a risk factor for treatment failure in adults who have mild to moderate asthma, according to a large, retrospective cohort study published online June 11 in the American Journal of Respiratory and Critical Care Medicine . (medscape.com)
  • Phosphine is a respiratory tract irritant that attacks primarily the cardiovascular and respiratory systems causing peripheral vascular collapse, cardiac arrest and failure, and pulmonary edema. (cdc.gov)
  • Management of respiratory failure. (cdc.gov)
  • Various aspects of respiratory failure are discussed. (cdc.gov)
  • Acute respiratory failure is defined. (cdc.gov)
  • Physical symptoms and causes of respiratory failure are described. (cdc.gov)
  • Complications of respiratory failure are considered. (cdc.gov)
  • This study describes a high-frequency oscillatory ventilation (HFOV) protocol for term and near-term infants with acute respiratory failure (ARF) and reports results of its prospective application. (unboundmedicine.com)
  • The patient presented to his local hospital 1 week after RUX treatment discontinuation with acute hypoxemic respiratory failure and hypotension. (ajmc.com)
  • Mycobacterium tuberculosis treatment regimens of bedaquiline and clofazimine had failed. (cdc.gov)
  • It has adequate regimens and/or shortened peri- been shown that patients treated without ods of treatment are prescribed [ 6 ]. (who.int)
  • If the heart remains weak with standard heart failure treatments, advanced treatment options for severe heart failure include insertion of a pump for your heart. (doereport.com)
  • Another advanced treatment for severe heart failure is a heart transplant. (doereport.com)
  • Treatment of severe heart failure: quantity or quality of life? (bmj.com)
  • The greatest benefit is seen in those patients with the most severe heart failure. (nps.org.au)
  • However, despite the improved survival, the prognosis of moderate-to -severe heart failure remains poor. (nps.org.au)
  • Since their introduction in the mid-1980s, angiotensin converting enzyme (ACE) inhibitors have become well established for the treatment of hypertension and heart failure. (nps.org.au)
  • Polymorphisms of the adducin genes have been demonstrated to be associated with hypertension and progression of the renal failure. (justia.com)
  • The most recent guidelines on heart failure of the European Society of Cardiology were published in 2021. (bvsalud.org)
  • Treatment is even more challenging in people with heart failure and preserved ejection fraction (HFpEF), with currently no approved therapy demonstrating a mortality-improving effect, limiting treatment to diuretics for the alleviation of the symptoms of fluid overload and risk factor management. (springer.com)
  • There are currently no treatments demonstrating mortality benefit for people with heart failure and preserved ejection fraction (HFpEF). (springer.com)
  • In heart failure with mildly reduced ejection fraction (HFmrEF), ARNIs, and SGLT2 inhibitors may be helpful. (merckmanuals.com)
  • The purpose of the authors' investigation was to determine the effects of percutaneous mitral annuloplasty on symptoms, 6-minute walk distance, and left ventricular (LV) structure and function in patients with mild or moderate SMR in heart failure with reduced ejection fraction. (cardiacdimensions.com)
  • The guidelines of the American Society of Cardiology set the treatment by gliflozins regardless of ejection fracion. (bvsalud.org)
  • Always seek the advice of a qualified physician for medical diagnosis and treatment. (medindia.net)
  • If diagnosis and treatment take place shortly after birth, the outlook for infants with RDS is good. (medicalnewstoday.com)
  • During a Dec. 8 chat, experts explain how Temple helps patients gain back their quality of life through diagnosis and treatment of advanced heart failure. (6abc.com)
  • In this chat, we will discuss how Temple helps patients gain back their quality of life through diagnosis and treatment of advanced heart failure. (6abc.com)
  • I have seen many important and positive changes around Chagas disease awareness, diagnosis, and treatment over the past few years, b ut there is still much to do. (cdc.gov)
  • SHIFT study contributed to a shift in the way we see the heart failure to show us that we have more than the intervention on the renin-angiotensin-aldosterone and the adrenergic system that is highly beneficial for our patients and our health system. (scielo.org.ar)
  • At a second time, the testimonies are drawn from the research project and intervention Aleph, about the Etiologies of the School Failure, developed in the postgraduation course of The Federal University of Rio De Janeiro. (bvsalud.org)
  • Patients identified with treatment failure rect economic burden attributed to absence have more localized disease as shown on from work and inability to work. (who.int)
  • Of the 251,947 cases identified, 55,741 patients (22.1%) needed further antibiotic treatment or ended up in the hospital. (medscape.com)
  • Failure rates were similar, regardless of the class of antibiotic used. (medscape.com)
  • The San Francisco Department of Public Health (SFDPH) is investigating several clinical failures in syphilis patients treated with the macrolide antibiotic azithromycin. (cdc.gov)
  • Tuberculosis treatment failure associated with evolution of antibiotic resilience. (harvard.edu)
  • Delayed treatment for more than 2 months and antibiotic -alone treatment were 2 independent risk factors for treatment failure of NTM SSTIs. (bvsalud.org)
  • Delayed treatment for more than 2 months and antibiotic -alone treatment were associated with a higher failure rate in patients with NTM SSTIs. (bvsalud.org)
  • Early identification of causative NTM species and appropriate antibiotic treatment may lower the risk of treatment failure . (bvsalud.org)
  • Genotypic and and clofazimine resistant (MIC = 2 mg/L). A deletion phenotypic bedaquiline susceptibility testing displayed was found in Rv0678 different from those identified variable results over time and ultimately were not predic- in S1: deletion at position 293 (N98fs) (97%), whereas tive of treatment outcome. (cdc.gov)
  • Treatment failure is a health treatment failure accounts for 3%-5% and economic burden as the patient re- of the treatment outcome of new smear- mains a source of infection in the commu- positive cases and 13%-17% of re-treated nity and it may lead to the development of cases [ 4 ]. (who.int)
  • One of direct observation have a substantially the most important causes of unsuccessful higher risk of adverse outcome than those treatment is irregularity and loss to follow- treated under direct observation [ 1 ]. (who.int)
  • Euthyroid outcome as an ultimate goal for treatment is favored, nonetheless hypothyroidism is a widely acceptable outcome. (snmjournals.org)
  • Results Logistic regression analysis shows a statistically significant effect of gender on treatment outcome following radioiodine therapy. (snmjournals.org)
  • Over the past 15 years, intestinal transplantation for the treatment of intestinal failure has changed from a desperate last-ditch effort into a standard therapy for which a good outcome is expected. (duke.edu)
  • During the follow-up, 24.4% died, 20% were not exposed to any HF treatment, 48.3 to 43.2% had diuretics, one third had BB or ACEI, 9% had ARB or AA, 6% had digoxin, and 2% had ivabradine. (nih.gov)
  • Since the buildup of fluids can cause heart failure, diuretics are the first things to be prescribed. (vetinfo.com)
  • Liver transplant as treatment for cardiac failure secondary to hereditary hemorrhagic telangiectasia. (scielo.cl)
  • PHESGO administration can result in subclinical and clinical cardiac failure. (gene.com)
  • with cardiac failure undergoing deferoxamine Tx. (medscape.com)
  • The 2013 article suggests that acute decompensated heart failure generally causes pulmonary congestion but does not usually affect blood volume. (medicalnewstoday.com)
  • ACE inhibitors thus help limit fluid retention and are one of the mainstays of systolic heart failure treatment. (merckmanuals.com)
  • The drugs prolong life better than ACE inhibitors or ARBs alone in people with systolic heart failure. (merckmanuals.com)
  • PERRONE, Sergio V . SHIFT trial (Systolic Heart failure treatment with the I f inhibitor ivabradine Trial): A SHIFT in the treatment of heart failure. (scielo.org.ar)
  • A 2015 article states that this type of heart failure has a high mortality rate and requires frequent hospitalizations. (medicalnewstoday.com)
  • Despite the progress made in the treatment of heart failure, it remains associated with high morbidity and mortality. (scielo.org.ar)
  • Although any degree of secondary mitral regurgitation (SMR) is known to further complicate heart failure symptoms and mortality, a treatment paradigm for patients with mild and moderate SMR is lacking. (cardiacdimensions.com)
  • Studies show a mortality rate of 2-10% in developed countries when treatment begins right away. (medicalnewstoday.com)
  • Incidence and hospital mortality due to heart failure. (scielo.cl)
  • Because BVPs help the heart's left and chambers to beat in a more coordinated fashion, this treatment is called cardiac resynchronization therapy (CST). (universityhealth.org)
  • BVPs are recommended for patients with heart failure that is not controlled with medication therapy and who have evidence of left-bundle branch block on their EKG. (universityhealth.org)
  • Objectives Radioactive iodine therapy has been used as a first-line treatment for hyperthyroidism as a result of Graves' disease, Toxic adenoma and multinodular goiter, however efforts to achieve the best treatment dose have never been ideal. (snmjournals.org)
  • Therapy using a fixed dose versus treatment base upon calculated dose has been debated. (snmjournals.org)
  • Conclusions The results of our series indicate that men have a higher likelihood of treatment failure following radioiodine therapy. (snmjournals.org)
  • Nevertheless, largely because of the potential survival benefit, most cardiologists now believe that an ACE inhibitor should be added to diuretic therapy in all patients with overt heart failure, even if the heart failure is only mild. (nps.org.au)
  • The addition of an ACE inhibitor to diuretic therapy improves the control of heart failure, an important symptomatic benefit. (nps.org.au)
  • If you've had repeated implantation failure following IVF or recurrent miscarriages, we offer a form of supportive treatment called Quad Therapy. (manchesterfertility.com)
  • We may recommend Quad Therapy to you if you've had repeated failed cycles of infertility treatment before, despite having good quality embryos, or repeated miscarriage. (manchesterfertility.com)
  • We will identify first whether Quad Therapy could help increase your chances of successful pregnancy and birth, as it's important to remember that not all patients benefit from it due to the varying causes of implantation failure and miscarriage. (manchesterfertility.com)
  • When it came to the type of therapy, age was a strong risk factor for failure on inhaled corticosteroids. (medscape.com)
  • For the treatment of falciparum malaria, WHO is recommending the use of a type of drug called artemisinin-based combination therapy, or ACTs. (cdc.gov)
  • PHESGO TM is indicated for use in combination with docetaxel for the treatment of adult patients with HER2-positive metastatic breast cancer (MBC) who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease. (gene.com)
  • A wide array of treatment options for HCC exist and include surgery, catheter-based therapies, radiation and systemic therapy. (intechopen.com)
  • Topical therapy with podophyllin resin 25% solution usually achieves resolution after 1-2 treatment applications. (medscape.com)
  • Episode 4: How to Mix Touch and Tech in Advanced Heart Failure Drs Michelle Kittleson and Jason N. Katz discuss how to navigate uncertain terrain using a few rules to balance choices, risks, and goals in managing device therapy for individuals with heart failure. (medscape.com)
  • Clinicians should exercise caution in using azithromycin for treating incubating syphilis or syphilis infection until the risk and mechanism of failure are better understood. (cdc.gov)
  • Several small studies have documented the efficacy of a single oral dose of azithromycin in the treatment of incubating and early syphilis infection in patients who were not infected with the human immunodeficiency virus (HIV) ( 1 ). (cdc.gov)
  • However, a 2-gram dose of azithromycin may be considered for penicillin-allergic patients, but only with close follow-up because treatment efficacy is not well documented and has not been studied in persons with HIV infection ( 2 ). (cdc.gov)
  • FRI treatment failure was defined by infection recurrence or amputation. (cam.ac.uk)
  • Therefore, the differential diagnosis of NTM infection should always be considered when the treatment course is prolonged but not effective. (bvsalud.org)
  • Because of the failure of hematologic components- white blood cells , red blood cells , and platelets -to develop, the body's capabilities to fight infection , deliver oxygen, and form clots are all diminished. (wikipedia.org)
  • Lifestyle changes and medication are popular treatment plans to combat heart failure. (sahealth.com)
  • Overall, 13.7% of the patients had a treatment failure, defined as an asthma exacerbation requiring steroids or an emergency department visit, a worsening of lung function, increased use of asthma rescue medication, or failure as judged by the physician. (medscape.com)
  • REHOVOT, ISRAEL-October 27, 2020- Acute liver failure is a devastating, rapidly progressing disease that results in death in 80% of cases, unless an emergency liver transplant is performed. (weizmann-usa.org)
  • This was a retrospective study using the medical records of patients who were registered for TB treatment over a five-year period between 2016 to 2020. (who.int)
  • Delayed treatment can lead to complications in treatment. (maxhealthcare.in)
  • However, as further studies were conducted, the drug was not only found to not help in the treatment of COVID but also had various side effects that could lead to further complications and even prove fatal for patients. (timesnownews.com)
  • Treatment Treatment of latent syphilis is intended to prevent occurrence or progression of late complications. (cdc.gov)
  • Without treatment, this can cause short- and long-term complications. (medicalnewstoday.com)
  • Without treatment, it can lead to serious complications, such as a stroke. (uclahealth.org)
  • MEDICAL ANIMATION TRANSCRIPT: This video will help you understand the main surgical procedures done to treat heart failure. (doereport.com)
  • Surgical treatment can be unsuccessful, and it is necessary to determine the predictive variables associated with FRI treatment failure, allowing one to optimise them prior to treatment and identify patients at higher risk. (cam.ac.uk)
  • Traditional mitral annuloplasty is an important treatment option for patients with FMR, but surgical risk and durability are important limitations. (cardiacdimensions.com)
  • Prompt surgical treatment is suggested if available. (bvsalud.org)
  • In the study, earlier menopause was associated with increased risk of heart failure, and this link was stronger in women who had natural rather than surgical menopause. (webmd.com)
  • Surgical resection, or partial hepatectomy (PH), is a potentially curative surgical treatment option for up to 15-20% of patients with HCC. (intechopen.com)
  • Treatment of intestinal failure: intestinal transplantation. (duke.edu)
  • Pioneering scientists at the Francis Crick Institute, Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (ICH) have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalised transplants for children with intestinal failure, according to a study published in Nature Medicine on Monday 7th September. (technologynetworks.com)
  • Children with intestinal failure cannot absorb the nutrients that are essential for their overall health and development. (technologynetworks.com)
  • The researchers took small biopsies of intestine from 12 children who either had intestinal failure or were at risk of developing the condition. (technologynetworks.com)
  • Acute renal failure is caused by damage to the kidneys, which can occur as a result of blood loss, toxins, or physical damage to the kidneys . (verywellhealth.com)
  • This type of treatment does not replace the work of the kidneys. (kidneyresearchuk.org)
  • Once the cause is found, the goal of treatment is to help your kidneys work again and prevent fluid and waste from building up in your body while they heal. (medlineplus.gov)
  • This is a treatment that does what healthy kidneys normally do -- rid the body of harmful wastes, extra salt, and water. (medlineplus.gov)
  • Symptoms of acute renal failure develop quickly, over several hours or days. (verywellhealth.com)
  • Acute decompensated heart failure is the most common form of acute heart failure and occurs in people with no previous heart failure symptoms. (medicalnewstoday.com)
  • Heart failure symptoms show up in a variety of ways. (sahealth.com)
  • The Centers for Disease Control and Prevention (CDC) estimate that there are 6.2 million adults with heart failure in the United States. (medicalnewstoday.com)
  • Sexually transmitted diseases treatment guidelines 2002. (cdc.gov)
  • This certification provides a framework for evaluating palliative/hospice agencies against the American Heart Association® evidence-based guidelines for heart failure patients. (heart.org)
  • Are SGLT-2 Inhibitors the Future of Heart Failure Treatment? (springer.com)
  • The trials will add substantially to our understanding of SGLT-2 inhibitors in the treatment of HFrEF and may have major implications for the treatment of people with HFpEF. (springer.com)
  • In this article we discuss the rationale for using SGLT-2 inhibitors in people with heart failure and explore the potential findings and importance of the ongoing EMPEROR-preserved and EMPEROR-reduced trials. (springer.com)
  • The EMPEROR trials will considerably add to our understanding of the future role for SGLT-2 inhibitors in people with heart failure, particularly HFpEF. (springer.com)
  • ACE inhibitors are among the most important drugs for treating patients with heart failure. (universityhealth.org)
  • Angiotensin receptor/neprilysin inhibitors (ARNIs) are a newer combination drug for the treatment of heart failure. (merckmanuals.com)
  • Beta-blockers are often used with ACE inhibitors to treat heart failure and are another mainstay of heart failure treatment. (merckmanuals.com)
  • Angiotensin converting enzyme inhibitors (ACE) and angiotensin receptor blockers (ARB) are standard heart failure treatments. (medicalxpress.com)
  • Fletcher P. ACE inhibitors in the treatment and prevention of heart failure. (nps.org.au)
  • There have now been several major studies investigating the role of ACE inhibitors in heart failure including the SAVE, SOLVD and AIRE studies. (nps.org.au)
  • ACE inhibitors improve survival in heart failure when added to conventional treatment. (nps.org.au)
  • ACE inhibitors started within 1-2 weeks of the infarction improve survival, reduce the chance of developing overt heart failure and reduce the need for hospitalisation. (nps.org.au)
  • Although the efficacy and safety of existing therapies of heart failure (HF) have been demonstrated in clinical trials, little is known about the treatment patterns in clinical practice, especially in France. (nih.gov)
  • According to the researchers, even after HCQ has not worked in the treatment of COVID-19, other drugs for malaria can still be used to treat COVID-19, and their efficacy should be assessed in clinical trials. (timesnownews.com)
  • Our finding that a shorter total reproductive duration was associated with a modestly increased risk of heart failure might be due to the increased coronary heart disease risk that accompanies early menopause," senior author Dr. Nisha Parikh said in a journal news release. (webmd.com)
  • Research also shows that even very high protein diets do not make renal failure worse in cats (although high protein does worsen the disease in dogs and humans). (catsofaustralia.com)
  • Depending on the severity of a patient's heart failure, one or more drinks may suddenly worsen symptoms. (universityhealth.org)
  • If the underlying problem causing the heart failure does not respond to treatment, then symptoms of heart failure can worsen over time. (healthguideinfo.com)
  • The present invention relates to 17-β-(3-furyl) and (4-pyridazinyl)-5-β, 14-β-androstane derivatives, as useful agents for preparing a medicament for the prevention and treatment of proteinuria, glomerulosclerosis and renal failure. (justia.com)
  • Watch and listen to Johns Hopkins cardiologists discuss prevention and treatment of heart failure. (hopkinsmedicine.org)
  • 5 allows us to reach millions of people globally with accurate and reliable resources about HIV prevention and treatment. (aidsmap.com)
  • New guidance from WHO aims to help countries identify groups at highest risk of TB so people can receive services for prevention and treatment. (bvsalud.org)
  • In April 2003, SFDPH became aware of an azithromycin failure in the treatment of primary syphilis in one patient and subsequently collected case information on this and seven other apparent treatment failures occurring during September 2002--July 2003. (cdc.gov)
  • A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. (who.int)
  • Une étude cas-témoins a été réalisée en Egypte dans les centres de traitement de la tuberculose entre avril 2001 et décembre 2002 afin de déterminer les facteurs prédictifs de l'échec du traitement. (who.int)
  • Various drugs and treatments used for other diseases such as malaria, HIV, or even for treatment of SARS and MERS, which were caused by genetic cousins of the novel coronavirus, have been repurposed and tested in the fight against COVID-19. (timesnownews.com)
  • Although chloroquine (CQ) monotherapy is now generally inadequate for the treatment of Plasmodium falciparum malaria in northern Ghana - recently, 58% of 225 children failed treatment by day 14 - use of the drug continues because of its low cost and wide availability. (elsevier.com)
  • In the current transition phase to alternative first-line treatment for P. falciparum malaria, it should be possible to provide estimates of the level of CQ resistance by monitoring the prevalences of these mutations. (elsevier.com)
  • Health Organization, about drug resistant malaria treatment in Vietnam. (cdc.gov)
  • In Vietnam, the recommended treatment for falciparum malaria has long been the ACT dihydroartemisinin-piperaquine. (cdc.gov)
  • Charlotte Rasmussen] The treatment for falciparum malaria in this area of Vietnam has now been changed to another ACT--artesunate-mefloquine. (cdc.gov)
  • IMSEAR at SEARO: Treatment of fulminant hepatic failure. (who.int)
  • Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia. (nih.gov)
  • Acute lymphoblastic leukemia causing hepatic failure. (scielo.cl)
  • These drugs improve survival and reduce hospitalization in people with heart failure. (merckmanuals.com)
  • Likewise, if a virus causes liver failure, supportive care can be given at a hospital to treat the symptoms until the virus runs its course. (maxhealthcare.in)
  • A traditional treatment for heart failure appears to be equally protective in preventing death or hospitalization among African-American patients, as compared to white patients, according to a study at Henry Ford Hospital in Detroit. (medicalxpress.com)
  • The retrospective study looked at insured patients who were hospitalized for heart failure at Henry Ford Hospital between January 2000 and June 2008, and who primarily received care through the Henry Ford Medical Group. (medicalxpress.com)
  • People who are hospitalized with this condition also have a very high rate of readmission within six months of initial hospital treatment. (healthguideinfo.com)
  • Usually, you will have to stay overnight in the hospital for treatment. (medlineplus.gov)
  • Data of patients with NTM SSTIs who received treatment between January 2014 and December 2019 at Taipei Veterans General Hospital were collected retrospectively. (bvsalud.org)
  • Patients with heart failure often go to the hospital when they are experiencing a noticeable increase in symptoms. (6abc.com)
  • Eman Hamad, MD is Director of the Advanced Heart Failure and Transplant Program, Director of the Cardio-Oncology Program, and Medical Director of the Mechanical Circulatory Support Program at Temple University Hospital. (6abc.com)
  • An analysis of liver tissue from human patients with acute liver failure revealed a molecular pattern strikingly similar to the one identified in mice in the study, raising hopes that the findings may in the future be translated into a treatment for humans. (weizmann-usa.org)
  • Indications for treatment include symptoms attributable to the lesion, or a patient's desire to eliminate the lesion for cosmetic reasons. (medscape.com)
  • Shared Decision-Making in Heart Failure Heart failure treatment can significantly affect a patient's quality of life. (medscape.com)
  • Acute renal failure occurs rapidly, causing generalized symptoms, such as nausea and confusion. (verywellhealth.com)
  • Acute liver failure occurs when your liver rapidly loses its ability to function. (maxhealthcare.in)
  • Decompensation occurs when the body is no longer able to compensate for the physical problems caused by heart failure. (healthguideinfo.com)
  • 4 Additionally, tolerance tends to develop slowly over time, whereas the increased pain resulting from opioid treatment in the OIH patient occurs relatively quickly. (uspharmacist.com)
  • Optimizing treatment strategies can reduce the number and severity of events. (bmj.com)
  • Only 59% of treated patients reported good adherence to treatment with positive airway pressure, and response to treatment correlated with OSA severity. (cdc.gov)
  • Patients with Epidermolysis Bullosa (EB) have a broad spectrum of need for pain and wound treatment, varying with the type of EB, the severity within that type, and the particular physical, emotional, and psychological milieu of each individual. (hrb.ie)
  • The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
  • Preventive health checkups can provide you with an early diagnosis of medical conditions, giving your treatment a headstart. (maxhealthcare.in)
  • They are helpful for diagnosing heart failure, determining how severe it is, and predicting your future health. (cardiosmart.org)
  • Dr. Kolodziejczyk and her colleagues began their investigation by creating gene expression profiles of 45,000 individual mouse liver cells, ultimately generating a comprehensive liver-cell atlas in conditions of health and acute failure. (weizmann-usa.org)
  • After Successful Congenital Heart Failure Surgery in India , She is now healthy and doing well in her studies, all thanks to the doctor, his team, Indian health guru consultants, and my family. (indianhealthguru.com)
  • Suspected gonorrhea cephalosporin treatment failure or any N. gonorrhoeae specimen with decreased cephalosporin susceptibility should be reported directly to CDC by either clinicians or health departments by completing the Suspected Gonorrhea Treatment Failure Consultation Form. (cdc.gov)
  • Call 310-582-6350 to learn more about vasculitis treatment at UCLA Health. (uclahealth.org)
  • The UCLA Health Vasculitis Program is the first comprehensive, multispecialty program dedicated to vasculitis treatment in Southern California. (uclahealth.org)
  • and second, the need for adequate mental health treatment is often unmet among. (hrb.ie)
  • However, treatment can only be prescribed if the provider thinks a bout Chagas disease as a health concern for their patient and knows how to diagnose and treat it. (cdc.gov)
  • Our results underscore the importance of FOXM1 in AML progression and treatment, and they suggest that targeting it may have therapeutic benefit in combination with standard AML therapies. (jci.org)
  • It can develop in people with preexisting heart failure and those without signs of the condition. (medicalnewstoday.com)
  • Signs of Renal failure in cats. (catsofaustralia.com)
  • 40-45%, in the absence of symptoms or signs of heart failure. (nps.org.au)
  • Watch for signs that your heart failure is getting worse, such as shortness of breath, or swelling in the legs or abdomen. (hopkinsmedicine.org)