LeukopeniaDrug Evaluation: Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Cisplatin: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.Infusions, Intravenous: The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.Hematologic Diseases: Disorders of the blood and blood forming tissues.Paclitaxel: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.Doxorubicin: Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.Antineoplastic Agents, Phytogenic: Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.Blood Cell Count: The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.Cyclophosphamide: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Lung Neoplasms: Tumors or cancer of the LUNG.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.Carboplatin: An organoplatinum compound that possesses antineoplastic activity.Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.Cellophane: A generic name for film produced from wood pulp by the viscose process. It is a thin, transparent sheeting of regenerated cellulose, moisture-proof and sometimes dyed, and used chiefly as food wrapping or as bags for dialysis. (Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Gastric Fistula: Abnormal passage communicating with the STOMACH.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Vinblastine: Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Taxoids: A group of diterpenoid CYCLODECANES named for the taxanes that were discovered in the TAXUS tree. The action on MICROTUBULES has made some of them useful as ANTINEOPLASTIC AGENTS.Leukocytes: White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).Bone Marrow DiseasesBone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.Phlebovirus: A genus of the family BUNYAVIRIDAE comprising many viruses, most of which are transmitted by Phlebotomus flies and cause PHLEBOTOMUS FEVER. The type species is RIFT VALLEY FEVER VIRUS.Granulocyte Colony-Stimulating Factor: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.Menogaril: A semisynthetic anthracycline with the amino sugar on the D ring. It displays broad-spectrum antineoplastic activity against a variety of tumors.Ehrlichia: Small, often pleomorphic, coccoid to ellipsoidal organisms occurring intracytoplasmically in circulating LYMPHOCYTES. They are the etiologic agents of tick-borne diseases of humans; DOGS; CATTLE; SHEEP; GOATS; and HORSES.DeoxycytidineSurvival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Camptothecin: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.Levamisole: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)Aminopterin: A folic acid derivative used as a rodenticide that has been shown to be teratogenic.Antimetabolites, Antineoplastic: Antimetabolites that are useful in cancer chemotherapy.Ehrlichiosis: A tick-borne disease characterized by FEVER; HEADACHE; myalgias; ANOREXIA; and occasionally RASH. It is caused by several bacterial species and can produce disease in DOGS; CATTLE; SHEEP; GOATS; HORSES; and humans. The primary species causing human disease are EHRLICHIA CHAFFEENSIS; ANAPLASMA PHAGOCYTOPHILUM; and Ehrlichia ewingii.Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.Mycophenolic Acid: An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Leucovorin: The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Alopecia: Absence of hair from areas where it is normally present.Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)Nogalamycin: An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.Carcinoma, Non-Small-Cell Lung: A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.Remission Induction: Therapeutic act or process that initiates a response to a complete or partial remission level.Stomatitis: INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP.Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Bunyaviridae Infections: Virus diseases caused by the BUNYAVIRIDAE.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Maximum Tolerated Dose: The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)Rickettsiaceae Infections: Infections with bacteria of the family RICKETTSIACEAE.Immunosuppressive Agents: Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.Antineoplastic Agents, Alkylating: A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)Ifosfamide: Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.Erythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Pneumonia, Staphylococcal: Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.Methotrexate: An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.Granulocytes: Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Recurrence: The return of a sign, symptom, or disease after a remission.Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Mechlorethamine: A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.Salvage Therapy: A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.Tegafur: Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Neoplasm Recurrence, Local: The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.Breast Neoplasms: Tumors or cancer of the human BREAST.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Infusions, Parenteral: The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.Recombinant Proteins: Proteins prepared by recombinant DNA technology.6-Mercaptopurine: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.Vincristine: An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Interferon-alpha: One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Ehrlichia chaffeensis: A species of gram-negative bacteria that is the causative agent of human EHRLICHIOSIS. This organism was first discovered at Fort Chaffee, Arkansas, when blood samples from suspected human ehrlichiosis patients were studied.Epirubicin: An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.Platinum: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".Epothilones: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).Organoplatinum Compounds: Organic compounds which contain platinum as an integral part of the molecule.Radiotherapy Dosage: The total amount of radiation absorbed by tissues as a result of radiotherapy.Endotoxins: Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.Guanine
  • The targeted therapy Verzenio (chemical name: abemaciclib) was approved by the U.S. Food and Drug Administration (FDA) on Sept. 28, 2017 to be used in combination with Faslodex (chemical name: fulvestrant) to treat women diagnosed with hormone-receptor-positive, HER2-negative, metastatic or advanced-stage breast cancer if the cancer progressed after hormonal therapy treatment. (breastcancer.org)
  • White blood cells are essential for proper immune system function, so it's important that a low white blood cell count is diagnosed and treated before a serious infection develops. (brighthub.com)
  • Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection. (news-medical.net)
  • EN is a hypersensitivity reaction resulting from exposure to a variety of infectious agents (especially recent streptococcal infection), drugs (including oral contraceptives), or systemic inflammatory disorders (eg, sarcoidosis, inflammatory bowel disease). (medscape.com)
  • In contrast to placebo treated controls, cats successfully treated with PMEA contained viral infection, developed neutralizing antibody, and resisted a second virulent virus challenge without further therapy. (nih.gov)
  • Not to be confused with the cancer leukemia, leukopenia is a condition in which the number of white blood cells (leukocytes) decreases, lowering the body's defenses and increasing the risk of infection ( 26 ). (healthline.com)
  • Phase II trial to study the effectiveness of combination chemotherapy in treating patients with newly diagnosed metastatic Ewing's sarcoma or primitive neuroectodermal tumor. (clinicaltrials.gov)
  • I. Evaluate the response rate and duration of response of patients with newly diagnosed, metastatic Ewing's sarcoma or primitive neuroectodermal tumor treated with maximally intensified VAdrC (vincristine, doxorubicin, cyclophosphamide) alternating with IE (ifosfamide, etoposide). (clinicaltrials.gov)
  • Verzenio also was approved to be used alone to treat women and men diagnosed with hormone-receptor-positive, HER2-negative, metastatic or advanced-stage breast cancer if the cancer progressed after hormonal therapy treatment and chemotherapy if the cancer is metastatic. (breastcancer.org)
  • The study found that women diagnosed with metastatic, hormone-receptor-positive, HER2-negative breast cancer that had grown while being treated with hormonal therapy other than Faslodex had 7 months longer progression-free survival if they were treated with Verzenio and Faslodex compared to women treated with Faslodex alone. (breastcancer.org)
  • If you've been diagnosed with advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that has grown while being treated with hormonal therapy, you may want to talk to your doctor about Verzenio and ask if it makes sense for your unique situation. (breastcancer.org)
  • Cisplatin is a prescription medicine used to treat the symptoms of cancer in the testicles (Metastatic Testicular Tumors), bladder (Advanced Bladder Cancer ) and ovaries (Metastatic Ovarian Carcinoma). (rxlist.com)
  • This study evaluates the clinical benefit of pegylated liposomal doxorubicin (PLD) in patients with metastatic breast cancer (MBC), previously treated with conventional anthracyclines. (nature.com)
  • All patients were previously treated with chemotherapy and 30% of patients had ⩾ 3 prior chemotherapies for metastatic disease. (nature.com)
  • ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that ERBITUX(R) (cetuximab) has received marketing authorization in Japan for use in treating patients with advanced or metastatic colorectal cancer (mCRC). (redorbit.com)
  • On Feb. 3, 2015, the U.S. Food and Drug Administration (FDA) granted accelerated approval for using the targeted therapy Ibrance (chemical name: palbociclib) in combination with Femara (chemical name: letrozole) to treat locally advanced-stage or metastatic, estrogen-receptor-positive, HER2-negative breast cancer that hadn't been treated with hormonal therapy before in postmenopausal women. (breastcancer.org)
  • The first is as monotherapy for patients with HR+/HER2- advanced breast cancer previously treated with endocrine therapy and chemotherapy for metastatic disease. (curetoday.com)
  • The study, Chemosaturation with percutaneous hepatic perfusion of melphalan for liver dominant metastatic uveal melanoma: a single center experience , by Dr. Christoph Artzner, et al, evaluated the safety and efficacy of PHP ® Therapy in 16 patients with unresectable liver metastases from ocular melanoma treated with CHEMOSAT between June 2015 and December 2018. (yahoo.com)
  • Nivolumab (Opdivo) to treat patients with metastatic non-small-cell lung cancer whose disease progressed during or after platinum-based chemotherapy. (acpinternist.org)
  • In a study of 582 participants with metastatic non-small cell-lung cancer, those treated with nivolumab lived an average of 12.2 months, compared to an average of 9.4 months in those who were treated with docetaxel. (acpinternist.org)
  • Pre-menopausal patients also have been treated with hormone therapy and CDK4/6 inhibitors, in addition to drugs that suppress ovarian production of estrogen, but there previously was a lack of data to confirm the utility of this approach, explained Tripathy. (mdanderson.org)
  • 1 Patients with non-deforming psoriatic arthritis without any radiographic changes, loss of range of motion, or interference with tasks of daily living should not automatically be treated with tumor necrosis factor (TNF) inhibitors. (aad.org)
  • Any drug used to treat cancer (including tyrosine kinase inhibitors or TKIs) can be considered chemo, but here chemo is used to mean treatment with conventional cytotoxic (cell-killing) drugs that mainly kill cells that are growing and dividing rapidly. (cancer.org)
  • 96%) patients was the most common haematological clinical manifestation, followed by leukopenia found in 166(25. (thefreedictionary.com)
  • "With this approval, treating PAD in the U.S. will begin to undergo the same revolution that drug elution did for treating coronary artery disease," added Gary Ansel, M.D., director for the Center for Critical Limb Care at Riverside Methodist Hospital in Columbus, Ohio, and an assistant clinical professor of medicine in the Department of Internal Medicine at the University of Toledo Medical Center in Toledo, Ohio. (cookmedical.com)
  • Clinical outcomes of locally advanced esophageal neuroendocrine carcinoma treated with chemoradiotherapy. (bioportfolio.com)
  • Lactate dehydrogenase and baseline markers associated with clinical outcomes of advanced esophageal squamous cell carcinoma patients treated with camrelizumab (SHR-1210), a novel anti-PD-1 antibody. (bioportfolio.com)
  • One large clinical trial suggested a specific echinacea formulation was as effective as a prescription drug to treat influenza, with fewer side effects. (mskcc.org)
  • Zhao P. Rheumatic arthritis treated with acupuncture: clinical observation of 368 cases. (healthy.net)
  • At the time of data collection, 12 patients were enrolled in the clinical trial at six centers in the U.S., and nine patients were treated with ALLO-501 at three dose levels. (mdanderson.org)
  • This case may suggest the existence of a subtype of T-CLL/PLL with leukopenia and an indolent clinical course. (springer.com)
  • Increased incidence of cerebrovascular adverse events (e.g., stroke, transient ischemic attack), including fatalities, have been reported in clinical trials of elderly patients with dementia-related psychosis treated with oral aripiprazole. (biospace.com)
  • [ 79 ] Positive clinical improvement was obtained when voriconazole at 200 mg was combined with terbinafine at 250 mg in treating one patient with refractory chromoblastomycosis. (medscape.com)
  • The efficacy of Latuda as adjunctive therapy was established in a 6-week study in adult patients with bipolar depression who were treated with lithium or valproate [see Clinical Studies ]. (healthyplace.com)
  • A drug that is used to treat chronic lymphocytic leukemia (CLL) and slow-growing B-cell non-Hodgkin's lymphomas (NHL) such as Waldenstrom's macroglobulinemia. (iwmf.com)
  • For over 30 years cyclophosphamide (CYC) and chlorambucil (CHL) have been used to treat children with relapsing steroid-sensitive nephrotic syndrome (SSNS). (nih.gov)
  • Seventy-nine women with MBC previously treated with anthracyclines received PLD 50 mg m −2 every 4 weeks. (nature.com)
  • Among the 85 previously treated patients, the median interval since onset of illness was 24 months. (cdc.gov)
  • We conducted an exploratory case-control study of patients previously treated for HGE to assess health status, symptoms, and changes in serologic status. (cdc.gov)
  • Millions of adults and children are developing serious health problmes by living in homes previously treated with the now banned pesticide chloridane. (chem-tox.com)
  • Chlordane contaminates the air of over 30 million U.S. homes by diffusion through concrete flooring - ceiling drywall - or outgassing from previously treated indoor areas. (chem-tox.com)
  • They then tested these cells against non-enriched stem cells to determine their benefit to the treated mice. (medindia.net)
  • AGAF was evaluated to ease the leukopenia in CT26-colon-cancer-bearing mice treated with 5-fluorouracil (5-FU). (hindawi.com)
  • In vivo examination showed that the oral administration of AGAF mitigated the side effects of leukopenia caused by 5-FU in colon-cancer-bearing mice. (hindawi.com)
  • There are also reports of leukopenia caused by divalproex sodium or valproic acid (Depakote), a drug used for epilepsy (seizures), mania (with bipolar disorder) and migraine. (wikipedia.org)
  • Another complication of oral prednisone, mg/kg/d, may be used to treat the underlying disorder. (visitmayberry.com)
  • An adolescent boy aged 14 years ( Table ) had ILI symptoms on December 26, 2006, and was taken to a local ED, where he was treated with clarithromycin and penicillin for atypical pneumonia and pharyngitis. (cdc.gov)
  • This is a Clonazepam side effect report of a 19-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Clonazepam (dosage:NA, start time: NS), combined with: NA. (patientsville.com)
  • Patients receiving intrathecal cytarabine should be treated concurrently with dexamethasone to mitigate symptoms of chemical arachnoiditis. (thefreedictionary.com)
  • A side-effect of some forms of chemotherapy or radiotherapy used to treat leukaemia and other cancers. (leukaemia.org.au)
  • Melphalan/HDS has not been approved by the U.S. Food & Drug Administration (FDA) for sale in the U.S. In Europe, our system is marketed under the trade name Delcath Hepatic CHEMOSAT® Delivery System for Melphalan (CHEMOSAT) and has been used at major medical centers to treat a wide range of cancers of the liver. (yahoo.com)
  • A medicine used to treat advanced breast cancer in postmenopausal women. (lbbc.org)
  • The FDA approval is based on results from the PALOMA-1 trial, which was a phase II trial that involved 165 women, which found that postmenopausal women diagnosed with advanced-stage, estrogen-receptor-positive, HER2-negative breast cancer treated with the combination of Ibrance and Femara lived twice as long without the cancer growing compared to women who got only Femara. (breastcancer.org)
  • Subsequent evaluation discovered this patient had coronary artery occlusion which was successfully treated. (yahoo.com)
  • OBJECTIVE: To evaluate the efficacy and safety of sodium copper chlorophyllin (trademarked as "Yebaike Tablet which is abbreviated as YBK in treating leukopenia. (lifeextension.com)
  • SAN ANTONIO Results of the GeparQuinto study, randomized Phase III efficacy data on the use of bevacizumab plus chemotherapy to treat women with early breast cancer will be presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium. (bio-medicine.org)