The transference of a complete HAND, as a composite of many tissue types, from one individual to another.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster's New Geographical Dictionary, 1988, p842 & Room, Brewer's Dictionary of Names, 1992, p378)
A group of islands in the southwest central Pacific, divided into AMERICAN SAMOA and the INDEPENDENT STATE OF SAMOA (Western Samoa). First European contact was made in 1722 by Jacob Roggeveen, a Dutchman. In 1768 they were named Navigators Islands by Louis de Bougainville. The present name may derive from that of a local chieftain or from a local word meaning place of the moa, a now-extinct island bird. (From Webster's New Geographical Dictionary, 1988, p1061 & Room, Brewer's Dictionary of Names, 1992, p481)
The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.
The transference of a part of or an entire liver from one human or animal to another.
Pathological processes of the LIVER.
Non-cadaveric providers of organs for transplant to related or non-related recipients.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.
Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.
The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
A publication issued at stated, more or less regular, intervals.
Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
A shaker subfamily that is prominently expressed in NEURONS and are necessary for high-frequency, repetitive firing of ACTION POTENTIALS.
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
The transference of a kidney from one human or animal to another.
Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).
Transplantation of STEM CELLS collected from the fetal blood remaining in the UMBILICAL CORD and the PLACENTA after delivery. Included are the HEMATOPOIETIC STEM CELLS.
Transference of an organ between individuals of the same species or between individuals of different species.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).
Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.

Organ transplantation--then and now. (1/498)

The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation. Our distinguished authors focus on these developments and discuss how the momentum seen during the last quarter century can be accelerated.  (+info)

Transplant surgeons in training: is anybody out there? (2/498)

There is a long-standing recognition that there is an organ donor shortage in the United Kingdom and Ireland (UK&E) that limits transplant activity. However, the fact that, at present, there are several unfilled consultant vacancies would suggest that a shortage of trained surgeons may soon be an equally important limiting factor. The aim of this current study was to identify all transplant trainees in the UK&E and to determine their career aspirations. A list of all trainees intending to practice as transplant surgeons was compiled. A combination of postal questionnaire and telephone interview was used to construct a database on past and present training in transplantation, and preferred type of consultancy was assessed both by direct questioning and by using a visual analogue scale to grade desirability of various posts. Of 110 potential trainees identified, 50 (45%) replied and indicated a desire to pursue a career in transplant surgery. Thirty-one intended practising in the UK&E (19 UK&E graduates and 12 overseas). The preferred consultancy (27/31) was transplantation (Tx) together with a second specialty while only four wanted a multivisceral practice. The mean score (0-10) for desirability of a multivisceral transplant post was 4.7, for renal transplant and vascular access it was 3.6 and for transplantation and a second specialty it was 8.4. We conclude that the majority of trainees do not wish to apply for pure transplant posts, either single organ or multivisceral, and that the majority wish to practice transplantation with a second specialty. In addition, there is still a major shortage of trainees and further studies are required to identify reasons why trainees fail to pursue a career in transplantation.  (+info)

Gene targeting: applications in transplantation research. (3/498)

Gene targeting, the manipulation of gene in the mouse genome using homologous recombination in embryonic stem cells, is a powerful experimental tool that has been widely utilized in a number of disciplines. The ability to precisely alter genes in this way provides an avenue for investigating the role of a gene product in normal and pathological processes in the intact animal, with a precision and efficacy not possible using pharmacological agents, antibodies or engineered proteins. In transplant research, gene targeting provides a unique tool for discriminating the contributions of gene expression in donor versus recipient tissues. This review focuses on several areas in transplantation research where gene targeting has made useful contributions. These include studies of the role of donor and recipient multiple histocompatibility complex antigens in regulating rejection responses, the role of CD4+ T cell in mediating acute rejection, and the functions of cytokines during rejection and tolerance induction. These studies highlight the unique advantages of gene targeting in studies of complex processes in whole animals and illustrate the contributions of this technique to understanding the pathogenesis of allograft rejection.  (+info)

Gene therapy in transplantation in the year 2000: moving towards clinical applications? (4/498)

Transplantation faces several major obstacles that could be overcome by expression of immunomodulatory proteins through application of gene therapy techniques. Gene therapy strategies to prolong graft survival involve gene transfer of immunosuppressive or graft-protecting molecules. Very promising results have been obtained in small animal experimental models with inhibitors of co-stimulatory signals on T cells, immunosuppressive cytokines, donor major histocompatibility antigens and regulators of cell apoptosis or oxidative stress. The application of gene therapy techniques to transplantation offers a great experimental and therapeutic potential. Local production of immunosuppressive molecules may increase their therapeutic efficiency and reduce their systemic effects. When compared with other clinical situations, gene therapy in transplantation offers several potential advantages. Gene transfer into the graft can be performed ex vivo, during the transit between the donor and the recipient, thus avoiding many of the hurdles encountered with in vivo gene transfer. Furthermore, the difficulties associated with immune responses to the gene transfer vectors and transient gene expression may be easier to overcome when gene therapy protocols are applied to transplantation than when applied to other clinical situations. The next century should witness a rapid increase in the application of gene therapy techniques to large animal pre-clinical models of transplantation and later to clinical trials. Gene Therapy (2000) 7, 14-19.  (+info)

The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. (5/498)

Whereas the standard immunosuppressive agents foster development of posttransplant lymphoproliferative disorders (PTLDs), the impact of RAD, a macrolide with potent immunosuppressive properties, and other immunosuppressive macrolides on these disorders remains undetermined. We found that RAD had a profound inhibitory effect on in vitro growth of six different PTLD-like Epstein-Barr virus+ lymphoblastoid B cell lines. Similar to normal T cells, RAD blocked cell-cycle progression in PTLD-like B cells in the early (G(0)/G(1)) phase. Furthermore, RAD increased the apoptotic rate in such cells. The drug also had a profound inhibitory effect on the growth of PTLD-like Epstein-Barr virus+ B cells xenotransplanted s.c. into SCID mice. The degree of the RAD effect varied among the three B cell lines tested and was proportional to its effects on the cell lines in vitro. In this in vivo xenotransplant model, RAD markedly delayed growth or induced regression of the established tumors. In one line, it was able to eradicate the tumor in four of eight mice. When RAD treatment was initiated before tumor cell injection, a marked inhibition of tumor growth was seen in all three lines. In two of them, the drug prevented tumor establishment in approximately 50% of mice (5/11 and 5/8). In summary, RAD is a potent inhibitor of PTLD-like cells in vitro and in vivo. These findings indicate that, in contrast to the standard immunosuppressive agents, macrolides such as RAD may be effective in prevention and treatment of PTLDs.  (+info)

Comparison of quantitative cytomegalovirus (CMV) PCR in plasma and CMV antigenemia assay: clinical utility of the prototype AMPLICOR CMV MONITOR test in transplant recipients. (6/498)

The correlation between the prototype AMPLICOR CMV MONITOR test (Roche Molecular Systems), a quantitative PCR assay, and the cytomegalovirus (CMV) pp65 antigenemia assay was evaluated in transplant recipients. Sequential blood specimens were collected on 29 patients (491 specimens), the leukocyte fraction was tested by CMV antigenemia, and quantitative PCR was performed on plasma specimens. None of the 15 patients (242 specimens) who were antigenemia negative were positive for CMV DNA by PCR, and none of these patients developed active CMV disease. There were 14 antigenemia-positive patients, 8 of whom developed active CMV disease. In all patients, there was a good association between the antigenemia and PCR assays. Ganciclovir-resistant virus was isolated from three patients with active CMV disease. These three patients had persistently elevated levels of antigenemia and CMV DNA by PCR when resistance to ganciclovir developed. This standardized, quantitative CMV PCR assay on plasma has clinical utility for the diagnosis of active disease and in monitoring the response to antiviral therapy in transplant recipients.  (+info)

Transcatheter implantation of a bovine valve in pulmonary position: a lamb study. (7/498)

BACKGROUND: Pulmonary regurgitation can lead to severe right ventricular dysfunction, which is a delicate postoperative problem in the long-term follow-up of patients who had surgery for congenital heart diseases. Clinical conditions of patients suffering from pulmonary valve incompetence are improved by valve replacement with a prosthetic valve. To date, the surgical approach is the only option to replace a pulmonary valve. We report the first experience of percutaneous pulmonary valve implantation. METHODS AND RESULTS: A fresh bovine jugular vein containing a native valve was sutured into a vascular stent and then cross-linked with a 0.6% glutaraldehyde solution for 36 hours. After being hand-crimped onto a balloon catheter, the device was inserted percutaneously according to standard stent-placing techniques. The valved stent was finally deployed in the position of the native pulmonary valve of the lamb. Hemodynamic evaluation was carried out before and 2 months after implantation. Anatomic evaluation was finally performed. Percutaneous pulmonary valve replacement was successful in 5 lambs. No complications were noted. Early and late angiographic and hemodynamic studies confirmed a good position of the stents with a competent valve at the end of the protocol. One stent was slightly stenotic, with macroscopically visible calcifications. CONCLUSIONS: Nonsurgical implantation of pulmonary valves is possible in the lamb. This new technique is similar to standard stent implantation. Thus, it should be feasible in humans, in whom it will lead to a significant reduction of reoperations in patients in need of pulmonary valve replacement.  (+info)

Therapeutic surgery in failures of medical treatment for fungal keratitis. (8/498)

Medical treatment failure necessitated surgery in nine cases of fungal keratitis. Therapeutic surgery eliminated fungal infection in seven cases, and useful vision was retained in five out of six penetrating keratoplasties. In three cases Natamycin (Pimaricin) therapy rendered fungi non-viable, but two were demonstrable by histopathology. These results suggest that antifungal treatment should be applied for as long as possible before therapeutic surgery in order to improve the final visual outcome.  (+info)

American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Avoidance of long-term immunosuppression is a desired goal in organ transplantation. Mixed chimerism offers a promising approach to tolerance induction, and we have aimed to develop low-toxicity,.... ...
The American Society of Transplantation is dedicated to advancing the field of transplantation and improving patient care by promoting research, education, advocacy, organ donation, and service to the community.. ...
SOUTH SAN FRANCISCO, Calif., May 09, 2016-- Atara Biotherapeutics, Inc., a biopharmaceutical company focused on developing meaningful therapies for patients with severe and life-threatening diseases that have been underserved by scientific innovation, today announced that an oral presentation, entitled
Submit Late Breaking Abstract This site is available for late breaking data only. Abstracts submitted for late breaking consideration that do not include research conducted after December 2, 2017, will not be considered for presentation. Deadline: January 26, 2018, 11:59 PST
S. Park1, C. Baek2, M. Yu3, Y. Kim1, J. Moon1, H. Go2, Y. Kim2, J. Lee4, S. Min1, J. Ha1, K. Moon1, Y. Kim1, C. Ahn1, S. Park2, H. Lee1. ...
I. Revuelta,1,2,3,4 V. Tubita,2 D. Cucchiari,1,2 E. De Sousa,1 P. Piselli,5 M. Lozano,6 J. Cid,6 E. Palou,7 J. Martorell,7 F. Oppenheimer,1,2,3,4 F. Diekmann,1,2,3,4 J. Campistol.1,2,3,4. ...
Teleflex Incorporated (NYSE:TFX) , a leading global provider of medical devices for critical care, urology and surgery, will showcase its range of interventional products at the 52nd European Renal, Dialysis and Transplant Congress in London on May 28 - 31, 2015. During the event, Teleflex will highlight its Arrow(R) chronic hemodialysis catheter portfolio, which offers both split-tip and step-tip catheters for both retrograde and antegrade insertion techniques. The Arrow(R) NextStep(R) Retrograde and Antegrade product family consists of step-tip catheters that can easily be inserted and tunneled using retrograde or antegrade technique, respectively. These step-tip catheters also have the advantage of split-tip high flow characteristics. The step-tip on these catheters is designed for smooth, over-the-wire transitions during insertions and exchanges. The Arrow(R) Cannon(R) II Plus and Arrow Edge(R) products are split-tip catheters that can be tunneled using retrograde or antegrade technique, ...
The Healthcare-Associated Infections Surveillance Network (HAI-Net) is a European network for the surveillance of healthcare-associated infections (HAI). The network is coordinated by the ECDC.. Activities of the Healthcare-associated Infections Surveillance Network (HAI-Net) are:. ...
Dr. Manikkam Suthanthiran pursues research in transplantation immunology and molecular biology to improve outcomes following organ transplantation.. Molecular Medicine. Dr. Suthanthirans laboratory has pioneered the development of noninvasive gene-based assays to ascertain kidney transplant status, which had previously required an invasive kidney biopsy procedure. The original study, first conducted at Weill Cornell, led to an NIH-sponsored multicenter Cooperative Clinical Trial in Transplantation comprised of 500 subjects from major transplant centers in the United States. Results of the molecular studies of transplant recipients were presented at the plenary sessions of the 2011 American Transplant Congress Annual Meeting and the 2011 International Transplantation Society Meeting. Based on the bench-to-bedside approach, this study has led to state-of-the-art, individualized care (personalized medicine) of kidney transplant recipients. Recently, Dr. Suthanthiran and his research team have ...
Patients who receive transplanted kidneys from deceased donors (DDs) age 60 and older with acute kidney injury (AKI) have worse allograft outcomes than some other DD kidney recipients, according to new research discussed at the 2019 American Transplant Congress in Boston.. A team led by J. Kim, MD, of Daejeon St. Marys Hospital at the Catholic University of Korea, examined clinical outcomes for 709 kidney transplant recipients (KTRs) receiving kidneys from 569 DDs at 4 transplant centers. For analyses, KTRs were stratified by donor age (younger or older than 60 years) and the presence of donor AKI. Allograft function deteriorated significantly more in recipients of AKI kidneys from older versus younger DDs: Estimated glomerular filtration rate (eGFR) was 46.8 vs 56.0; 45.3 vs 56.0; and 46.7 vs 61.4 mL/min/1.73 m2 at 3, 6, and 12 months after transplant, respectively, by the Modification of Diet in Renal Disease equation. At 12 months, grafts from AKI-young DDs fared similarly to those from ...
The research interests of Sadia Shah, M.D., are in Interstitial Lung Disease, Lung Transplant and Larynx-Trachea Transplant. She is a member of International Society of Heart and Lung Transplantation and American Transplant Congress. She is part of Mayo Clinic Transplant Convergence Group which collaborates between Mayo Clinic Arizona, Minnesota and Florida Transplant Division to ensure that all sites provide the latest and best care to lung transplant patients that the world has to offer.. Dr. Shah is currently the Interim Medical Director for Lung Transplant Program at Mayo Clinic Arizona and has been involved with re-launching of the program. She is also the Medical Director for Larynx-Trachea Transplant Program at Mayo Clinic, Arizona.. Focus areas. ...
As Professor of Surgery and Director of the Abdominal Transplant Fellowship Program at UCSF, Dr. Sandy Feng performs liver, kidney and pancreas transplants and teaches surgical fellows, residents, and medical students. She received a doctorate in molecular biology from Cambridge University with her Marshall Scholarship and earned her medical degree at Stanford University School of Medicine. She then completed general surgery residency at the Brigham and Womens Hospital in Boston and a transplant fellowship at the University of California, San Francisco.. Dr. Feng has numerous leadership roles, including Councilor for the American Society of Transplant Surgeons, Deputy Editor for the American Journal of Transplantation, former Co-Chair of the Executive Planning Committee for the American Transplant Congress, and current Chair of the Kidney Pancreas Advisory Committee of the American Society of Transplantation. She has been an invited organizer or participant in several national consensus ...
TY - JOUR. T1 - Clinical and economic consequences of first-year urinary tract infections, sepsis, and pneumonia in contemporary kidney transplantation practice. AU - Naik, Abhijit S.. AU - Dharnidharka, Vikas R.. AU - Schnitzler, Mark A.. AU - Brennan, Daniel C.. AU - Segev, Dorry L.. AU - Axelrod, David. AU - Xiao, Huiling. AU - Kucirka, Lauren. AU - Chen, Jiajing. AU - Lentine, Krista L.. N1 - Funding Information: The data reported here have been supplied by the United States Renal Data System (USRDS). The interpretation and reporting of these data are the responsibility of the authors and in no way should be seen as an official policy or interpretation of the United States government. This work was supported by a grant from the National Institutes of Health (NIH)/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R0-1DK102981. An abstract describing portions of this work was presented at the 2015 American Transplant Congress in Philadelphia, PA, May 3, 2015. Support ...
Nov 2011 - May 2015: Community Relations Coordinator, Donor Alliance. Jan 2009 - Dec 2013: Board Member, Colorado Healthcare Communicators. Jan 2011 - Sep 2011: Communication and Special Event Consultant, American Transplant Foundation. May 2008 - Sep 2010: Outreach & External Affairs Coordinator, American Transplant Foundation. Jan 2008 - Apr 2008: Communications Intern, American Transplant Foundation. - Denver, CO
Over the past forty years, the use of increasingly effective immunosuppressive drugs has decreased the risk for organ rejection (acute rejection, AR) considerably, and improved short-term outcomes. However, these costly and complicated life-long treatment regimens also cause serious complications in the long-term.. While transplant recipients live significantly longer lives than patients on dialysis, transplant recipients still have much shorter life spans than their healthy counterparts. Among reasons for this difference in life-expectancy are the immunosuppressive-drug related side effects that can lead to complications such as life threatening infections, malignancies, high blood pressure, heart disease, and diabetes. Additionally, certain drugs used to prevent organ rejection are known to contribute to renal damage, leading many patients to experience graft loss within 15 years. To that end, many children undergoing successful kidney transplantation require re-transplantation as adults. ...
Ajay Sharma, MD, Department of Paediatrics, University of Western Ontario, Childrens Hospital, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario, Canada N6A 5W9 Tel.: +1 519 685 8500 (ext. 58379) Fax: +1 519 685 8156 E-mail ...
ERN TransplantChild awards this grants to healthcare professionals who are currently dedicated to paediatric transplantation and wish to pursue a short-term training stay in any of the 25 health care providers (HCPs) members or affiliated partners of TransplantChild.. Get more information here.. ...
Kunzler de Oliveira Maia, F., Tekin, A., Nicolau-Raducu, R., Beduschi, T., Selvaggi, G., Vianna, R., Ammar Al Nuss, M., González, J., Gaynor, J. J. & Ciancio, G., Jan 1 2019, (Accepted/In press) In : Pediatric Transplantation. e13596.. Research output: Contribution to journal › Article ...
Alam, Z., VanderBrink, B. A., Brewer, N., Hooper, D., Tiao, G., Alonso, M., Nathan, J., DeFoor, W. R., Sheldon, C. & Reddy, P. P., Jan 1 2019, In : Pediatric Transplantation. 23, 5, e13453.. Research output: Contribution to journal › Article ...
TY - JOUR. T1 - Indoleamine 2,3-dioxygenase inhibition alters the non-coding RNA transcriptome following renal ischemia-reperfusion injury. AU - Merchen, Todd D.. AU - Boesen, Erika I.. AU - Gardner, John R.. AU - Harbarger, Rachel. AU - Kitamura, Eiko. AU - Mellor, Andrew. AU - Pollock, David M.. AU - Ghaffari, Arina. AU - Podolsky, Robert. AU - Nahman, N. Stanley. N1 - Funding Information: No conflicts. Supported by the Carlos and Marguerite Mason Trust (AM, TDM), a Clinical Investigator Award (TDM) and seed grant (TDM) from the Cardiovascular Discovery Institute, Georgia Regents University , a seed grant from the Immunotherapy Center, Georgia Regents University (NSN), and a research grant from the Augusta Biomedical Research Corporation, Augusta, Georgia (NSN). Portions of this work were previously presented at the 2012 American Transplant Congress 2012 and published in the American Journal of Transplantation: 13 (S5):385, 2013 and 13 (S5):386, 2013. Copyright: Copyright 2014 Elsevier B.V., ...
Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50-60 brain-dead donor organ transplants performed annually in Japan, however, very few (0-4 per year) are performed in children. Again, while those receiving liver, heart, and kidney transplants are reported to fare better than their counterparts in the rest of the world, organ shortage is becoming a matter of great concern. Very few organs become available from brain-dead donors or are transplanted to adults if made available at all, with some children dying while on the brain-dead organ waiting list. Against this background, living-donor transplants, split-liver transplants, domino transplants, and hepatocyte transplants represent alternative modalities, each of which is shown to be associated with favorable outcomes. Challenges exist, include streamlining the existing framework for promoting organ donation for children and between children.
1. Therapeutic options in hypertrophic cardiomyopathy: a pediatric perspective. Rhee EK. Nigro JJ. Pophal SG. Current Treatment Options in Cardiovascular Medicine. 10(5):433-41, 2008. 2. Left hemitruncus associated with tetralogy of fallot: fetal diagnosis and postnatal echocardiographic and cardiac computed tomographic confirmation. Diab K. Richardson R. Pophal S. Alboliras E. Pediatric Cardiology. 31(4):534-7, 2010. 3. Improved exercise performance in pediatric heart transplant recipients after home exercise training. Patel JN. Kavey RE. Pophal SG. Trapp EE. Jellen G. Pahl E. Pediatric Transplantation. 12(3):336-40, 2008. 4. Case-control study of risk factors for the development of post-transplant lymphoproliferative disease in a pediatric heart transplant cohort. Katz BZ. Pahl E. Crawford SE. Kostyk MC. Rodgers S. Seshadri R. Proytcheva M. Pophal S. Pediatric Transplantation. 11(1):58-65, 2007. 5. Ryan J1, Gregg C, Frakes D, Pophal S. Three-dimensional printing: changing clinical care or just ...
At least 32 young children have died since 2000 after failing to receive a heart transplant - a sign of South Africas faltering organ donation and transplantation programmes.. In one hospital in a five-year period from 2010 to 2014, two children received heart transplants while 10 died while wait-listed for a transplant.. These figures are directly linked to government policy, the nations poor commitment to organ donation generally and the difficulty of matching a young recipient to a small donor heart.. Only 80 children have received a heart transplant in this country in the 40 years that programmes have been operating, an average of two procedures a year.. According to figures presented by cardiothoracic surgeon Dr Susan Vosloo of the Christiaan Barnard Memorial Hospital at the Heart Transplant Society congress in Gordons Bay last week, the transplant programme for children started at Red Cross Childrens Hospital in association with Groote Schuur Hospital in Cape Town in 1980.. In the ...
The Pediatric Transplantation Program at Yale New Haven Childrens Hospital leads the way in providing expert, comprehensive and compassionate care to children with acute and chronic liver and kidney failure
Transplant-Associated and Blood Transfusion-Associated Tropical and Parasitic Infections: Blood transfusion and transplantation may represent efficient mechanis
M. J. Osorio, A. Bonow, G. J. Bond, et al. Abernethy malforma- tion complicated by hepatopulmonary syndrome and a liver mass successfully treated by liver transplantation. Pediatric Transplantation, 2011, 15(7): E149-E151.
Suresh, S., Upton, J., Green, M., Pham-Huy, A., Posfay-Barbe, K. M., Michaels, M. G., Top, K. A., Avitzur, Y., Burton, C., Chong, P. P. E., Danziger-Isakov, L., Dipchand, A. I., Hébert, D., Kumar, D., Morris, S. K., Nalli, N., Ng, V. L., Nicholas, S. K., Robinson, J. L., Solomon, M. & 4 others, Tapiero, B., Verma, A., Walter, J. E. & Allen, U. D., Jan 1 2019, (Accepted/In press) In : Pediatric Transplantation. e13571.. Research output: Contribution to journal › Article ...
Abcam provides specific protocols for Anti-HLA Class I antibody [W6/32] (ab22432) : Flow cytometry protocols, Immunoprecipitation protocols…
Rejection and infection are primary causes of morbidity and mortality in solid organ transplant recipients. Current clinical practice relies on immunosuppressive drug levels measured in plasma to reflect the peripheral immune response in solid organ transplant recipients. Direct measurement of the number and functions of the immune cells themselves using multi-parameter flow cytometry may enable individualized immunosuppression management for organ transplant recipients. Multi-parameter flow cytometry will be used to compare levels and functional capabilities of multiple lymphocyte subsets between cohorts of patients receiving depletion induction and those receiving a non-depletion regimen. The activation state, cytotoxic potential and the functional capabilities of these cells will be examined within patients over the first six months post transplant ...
TY - JOUR. T1 - Graft failure after infant heart transplantation. T2 - Impact of extracorporeal membrane oxygenation on outcomes. AU - Mettler, B.. N1 - Copyright: Copyright 2014 Elsevier B.V., All rights reserved.. PY - 2014/2. Y1 - 2014/2. UR - UR - U2 - 10.1111/petr.12199. DO - 10.1111/petr.12199. M3 - Editorial. C2 - 24384044. AN - SCOPUS:84891756807. VL - 18. SP - 1. EP - 2. JO - Pediatric Transplantation. JF - Pediatric Transplantation. SN - 1397-3142. IS - 1. ER - ...
BACKGROUND: The incidence and epidemiology of invasive fungal infections (IFIs), a leading cause of death among hematopoeitic stem cell transplant (HSCT) recipients, are derived mainly from single-institution retrospective studies. METHODS: The Transplant Associated Infections Surveillance Network, a network of 23 US transplant centers, prospectively enrolled HSCT recipients with proven and probable IFIs occurring between March 2001 and March 2006. We collected denominator data on all HSCTs preformed at each site and clinical, diagnostic, and outcome information for each IFI case. To estimate trends in IFI, we calculated the 12-month cumulative incidence among 9 sequential subcohorts. RESULTS: We identified 983 IFIs among 875 HSCT recipients. The median age of the patients was 49 years; 60% were male. Invasive aspergillosis (43%), invasive candidiasis (28%), and zygomycosis (8%) were the most common IFIs. Fifty-nine percent and 61% of IFIs were recognized within 60 days of neutropenia and ...
In a study reported in JAMA Oncology, Acuna et al found a nearly threefold increased risk of cancer mortality in solid-organ transplant recipients compared with the general population in Ontario, Canada.. Study Details. The population-based cohort study included data from 11,061 patients who underwent solid- organ transplantation in Ontario between 1991 and 2010, including 6,516 kidney, 2,606 liver, 929 heart, and 705 lung transplantations, representing 85,557 person-years of follow-up through December 2011. Recipients had a median age of 49 years, and 64% were male.. Increased Risk. Of 3,068 deaths in the cohort, 603 (20%) were cancer-related. Cancer mortality was significantly higher in transplant recipients than in the general population (standardized mortality ratio [SMR] = 2.84, 95% confidence interval [CI] = 2.61-3.07). Risk remained higher (SMR = 1.93, 95% CI = 1.75-2.13) in analysis, excluding patients with pretransplantation cancers (n = 1,124). Increased risk was observed for all types ...
Heart transplantation (HT) is an acceptable method of treating severe heart diseases in children when all other options have been exhausted. It is primarily intended for children suffering from cardiomyopathies, less often for children with severe arrhythmias and congenital heart defects. This method of treating children requires a multidisciplinary specialist cooperation and support in the childs home surroundings. Goal: The main goal is to present the development of Croatian paediatric transplantation cardiology. The secondary goal is to raise awareness of heart transplantations in children in order to motivate organ donations, it being the most limiting factor of the method. Results of study: The first heart transplantation in a child in Croatia was performed in 2011. Transplantation preparations were performed in eleven children. Two of the children died while on the waiting list, one child was removed from the waiting list due to recovery, and in eight of the children a transplantation was ...
Gras, Jeremie ; Latinne, Dominique ; Reding, Raymond ; Otte, Jean-Bernard ; Wieers, Grégoire ; et. al. IL-10 as a potential marker of graft acceptance in pediatric liver transplantation: Outcomes of a prospective immunologic monitoring in 40 recipients..In: Pediatric Transplantation, Vol. 9, p. 49-49 (2005 ...
article{3004d42f-c464-4188-bf60-ba0491925d72, author = {Bennhagen, Rolf and Sörnmo, Leif and Pahlm, Olle and Pesonen, Erkki}, issn = {1399-3046}, language = {eng}, number = {6}, pages = {773--779}, publisher = {Wiley-Blackwell}, series = {Pediatric Transplantation}, title = {Serial signal-averaged electrocardiography in children after cardiac transplantation.}, url = {}, volume = {9}, year = {2005 ...
Cell Markers include Diagnostic Immunophenotyping, Stem Cell Transplantation, and Immune Deficiency.. Diagnostic Immunophenotyping. We provide a comprehensive flow cytometry service for malignancy diagnosis and disease monitoring for the greater Auckland and Northland areas. The majority of our work involves leukaemia and lymphoma diagnosis in partnership with our Haematologists and Pathologists.. We also perform Immunocytochemical staining. We are involved with clinical trials for these patient populations. Samples processed include peripheral blood, bone marrow, CSF, FNAs, tissues and other body fluids.. Stem Cell Transplantation. Our laboratory is an integral part of the FACT accredited adult and paediatric Transplantation service for Auckland City Hospital and Starship hospital. We monitor CD34 levels and evaluate the quality of cells for transplantation on both fresh and post cyropreserved samples. Our service handles transplantation of mobilised stem cells, bone marrow and cord blood from ...
Dr. Gross was one of the most highly esteemed leaders in the field of hematology/oncology. Among his over 200 manuscripts were papers advancing our understanding of neonatal hematology, sickle cell disease, hemophilia, management of children with leukemia and neuroblastoma, and the use of bone marrow transplantation as a therapeutic modality for children with cancer. Dr. Grosss work in the areas of stem cell biology, Vitamin E and its role in hemolysis, clinical transplantation and the role of marrow purging in pediatric transplantation formed the basis of our current understanding of these areas. His work even resulted in a patent for a new Hematopoietic growth factor-Uteroferrin, derived from porcine uterus. Dr. Gross received an undergraduate degree in Biology and Chemistry at Bowdin College, a masters in Experimental Embryology at Amherst and his MD degree at University of Rochester. After a stint in the Marines during WWII, Dr. Gross began his career at Rainbow Childrens Hospital, Case ...
AFP February 1, 2016 - 50% of transplant-related deaths are due to immunosuppressive drugs, mostly infections - Most immunosuppressive drugs are metabolized via cytochrome P450 3A4 - so lots of interactions - Transplant recipients have increased risk of CAD and cardiovascular death HTN - goal (expert recommendation) is less than 130/80 mmHg - CCB reduce…
The American Society of Transplantation is dedicated to advancing the field of transplantation and improving patient care by promoting research, education, advocacy, organ donation, and service to the community.. ...
HIV Solid Organ Transplant Candidate/Recipient answers are found in the Johns Hopkins HIV Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Officials with the Department of Motor Vehicles teamed up with organ transplant recipients to encourage people to volunteer to become organ donors - when getting their drivers licenses.
Submit clotted, unspun red top tubes (preferred); serum is also acceptable.. Specimens must arrive within 2 hours of collection.. Copy of requisition MUST accompany specimen(s).. ...
The coronavirus pandemic has affected all areas of medical care, and a new study finds it has delayed potentially life-saving organ transplants.
Two short months free from an oxygen tank were enough time to complete what Charles W. Bud Groft Jr. wanted to do.Family members say the 51-year-old Manchester resident never regretted the
Transplant Research Review features key medical articles from global Transplant journals with commentary from ******. Covering topics such as bone marrow transplant, kidney transplant, liver transplant, heart transplant, transplantation, stem cell transplant, lung transplant, corneal transplant, organ transplant, bone marrow transplant, pancreas transplant, organ harvesting, islet cell transplant, allogeneic transplant, orthotopic heart transplant, organ rejection, intestine transplant, transplantation immunology, cadaveric renal transplant, orthotopic liver transplant, skin transplant, cord blood transplant, cell transplant, paediatric transplantation, bladder transplantation, ovarian transplant, transplant surgery complications, tissue transplant, transplantation ethics, transplantation medicine, autotransplantation, autograft, allotransplantation, allograft, isotransplantation, isograft, xenotransplantation, xenograft, domino transplantation, ABO-incompatible transplantation, regenerative medicine,
Three clusters of organ transplant-associated lymphocytic choriomeningitis virus (LCMV) transmissions have been identified in the United States; 9 of 10 recipients died. In February 2011, we identified a fourth cluster of organ transplant-associated LCMV infections. Diabetic ketoacidosis developed in the organ donor in December 2010; she died with generalized brain edema after a short hospitalization. Both kidneys, liver, and lung were transplanted to 4 recipients; in all 4, severe posttransplant illness developed; 2 recipients died. Through multiple diagnostic methods, we identified LCMV infection in all persons, including in at least 1 sample from the donor and 4 recipients by reverse transcription PCR, and sequences of a 396-bp fragment of the large segment of the virus from all 5 persons were identical. In this cluster, all recipients developed severe illness, but 2 survived. LCMV infection should be considered as a possible cause of severe posttransplant illness ...
Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoid neoplasms associated with immunosuppression following solid organ transplantation or allogeneic hematopoietic stem cell transplantation. Mismatch...
Post-transplant lymphoproliferative disorder (PTLD) is a potentially life-threatening complication of immunosuppression and oncogenic viral infections.
After the cytomegalovirus vaccine Astellas licensed from Vical failed in a kidney transplant phase 2 study, hopes for the shot rested on a phase 3 trial in hematopoietic stem cell transplant recipients. But that hope has just been shattered too.
Legislation tackles disability-based discrimination of organ transplant recipients WASHINGTON, D.C. - U.S. Representatives Jaime Herrera Beutler (WA-03) and Katie Porter (CA-45) today reintroduced the Charlotte Woodward Organ Transplant Discrimination Prevention Act, which will prohibit using an individuals mental or physical disability as the sole basis of determining their eligibility for an organ transplant.. The bill, named after Charlotte Woodward, an advocate fighting against discrimination who has Down syndrome and received a heart transplant in 2012, clarifies that doctors, hospitals, transplant centers and other health care providers are prohibited from denying access to organ transplants solely based on a qualified individuals disability.. If an individual needs access to a life-saving organ transplant, they shouldnt be denied based on their disability - either physical or mental, Herrera Beutler said. Im proud to reintroduce this important legislation today named after ...
Solid Organ Transplant Recruiting Phase 2 Trials for Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) (DB10791 ...
Browse top heart transplant surgeons. CPMC Heart and Vascular Center. San Francisco, CA. Among the best heart transplant doctors in the United States.
Washington [US], May 7 (ANI): Researchers at Johns Hopkins have found that two doses of a vaccine against SARS-CoV-2 -- the virus that causes COVID-19 -- confers some protection for people who have received solid organ transplants, its still not enough to enable them to dispense with COVID safety measures including masks and physical distancing.
Dr Anant Kumar, Indias most reputed kidney transplant surgeon for organ transplant & robotic surgery for kidney cancer, organ transplant etc.
Panacea Global Hair Services provides Best Hair Transplant in Jagadhri at a reasonable cost. We are one of the leading Clinics that have the team of Best Hair Transplant Surgeon in Jagadhri.
Last year, there were a record number of organ transplants in the country, and in Maryland. Experts believe the increase is in part due to the growing heroin epidemic.
At 61, Irene Schneider has undergone three kidney transplants, several bouts of dialysis and endured a lifetime of hospital visits.
2 people had to die for me to still be here - Transplant recipient now transplant surgeon. Transplant recipient now transplant surgeon
OMER said that patients will initially receive 12 weekly intravenous doses of the drug and additional weekly dosing can be administered for partial responders as well as relapsers. The primary endpoint of the treatment is a reduction in proteinuria at 24 weeks after the start of dosing. Of course, Omeros Corporation has been informed by the FDA that this primary endpoint could suffice for approval. In a statement, Gregory A. Demopulos, M.D., Chairman and CEO at OMER, had the following to offer:. Were pleased to have received agreement from FDA for our OMS721 Phase 3 protocol in IgA nephropathy… Final preparations to begin the trial can now be completed and enrollment is expected to open in early February. To our OMS721 Phase 3 programs in IgA nephropathy and aHUS, we have recently added a third Phase 3 program in stem cell transplant-associated TMA. We look forward to ongoing discussions with both the FDA and EMA regarding the HCT-TMA Phase 3 trial as well as breakthrough and PRIME ...
theodp writes The Commercial Appeal reports that Dr. James Eason, the surgeon who performed Steve Jobs liver transplant, found himself grilled at length Monday by Shelby County Commission members. The Univ. of Tennessee-Methodist Transplant Institute, which Eason heads, is in a bitter dispute over...
- No evidence of CMX001-associated kidney toxicity was seen in stem cell transplant recipients who were enrolled in a 230-patient Phase 2 study to evaluate CMX0
Giving Hope … Making Miracles. Transplant Financial Coordinators Association Conference October 22, 2009 San Diego, California. Childrens Organ Transplant Association ®. Mission. Slideshow 535441 by mayes
Surgeons in Sweden have performed the worlds first synthetic organ transplant - an artificial windpipe transplanted in a cancer patient.
Illegal organ transplants are on the rise as the gap between demand and supply widens- heres a look at what law can do to protect people.
Today there are more than 119,000 people waiting for organ transplants in the U.S. Only a small fraction of them will get the organs they need. Weve discovered its not just how sick you are, but where you live can determine whether you get a lifesaving organ or not.
... (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived ... Biology of blood and marrow transplantation. American Society for Blood and Marrow Transplantation. 2 (1): 3-14. PMID 9078349. ... Wikimedia Commons has media related to Hematopoietic stem cell transplantation.. *Bone marrow transplant - How it is performed ... a b Memorial Sloan-Kettering Cancer Center , Blood & Marrow Stem Cell Transplantation , The Graft-versus-Tumor Effect Archived ...
Neural transplantation. Since early in the 1980s, fetal, porcine, carotid or retinal tissues have been used in cell transplants ...
Hematopoietic cell transplantation[edit]. On January 13, 2011, City of Hope performed its 10,000th hematopoietic stem cell ... Association of Community Cancer Centers, National Bone Marrow Transplantation Research Network, National Gene Vector Laboratory ... transplantation, which includes transplants of bone marrow, peripheral blood stem cells collected by apheresis, and umbilical ...
Transplantation[edit]. Because the beta cells in the pancreatic islets are selectively destroyed by an autoimmune process in ... Chatenoud L (2008). "Chemical immunosuppression in islet transplantation-friend or foe?". New England Journal of Medicine. 358 ... Islet transplantation for type 1 diabetes currently requires potent immunosuppression to prevent host rejection of donor islets ... Hogan A, Pileggi A, Ricordi C (2008). "Transplantation: current developments and future directions; the future of clinical ...
Kidney transplantation. Kidney transplants are the treatment of choice for end-stage kidney disease, which is one of the ... "Disease recurrence in paediatric renal transplantation". Pediatr. Nephrol. 24 (11): 2097-108. doi:10.1007/s00467-009-1137-6 ...
Islet cell transplantation[edit]. Main article: Islet cell transplantation. Islet cell transplantation may be an option for ... Pancreas transplantation[edit]. Main article: Pancreas transplantation. In some cases, a pancreas transplant can restore proper ... "Pancreas Transplantation: Indications and Consequences". Archived from the original on 15 July 2012. ... Hatipoglu, B (December 2016). "Islet Cell Transplantation and Alternative Therapies". Endocrinology and Metabolism Clinics of ...
Bone, muscle, and nerve transplantation experiments. From about September 1942 to about December 1943 experiments were ... and bone transplantation from one person to another.[9] Sections of bones, muscles, and nerves were removed from the subjects ...
Stem cell transplantation[edit]. In 2007, Timothy Ray Brown,[12] a 40-year-old HIV-positive man, also known as "the Berlin ... Schneider, Thomas (2011-03-10). "Evidence for the cure of HIV infection by CCR532/32 stem cell transplantation". Blood. 117 (10 ... One supposed cure to HIV-1 involves the creation of a disease-resistant immune system through transplantation of autologous, ... This study demonstrated the efficacy of a transplantation approach that ultimately allows for an enriched population of HSPCs ...
... , also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced ... Corneal transplantation. Cornea transplant approximately one week after surgery. Multiple light reflections indicate folds in ... The corneal transplantation is performed when medicines, keratoconus conservative surgery and cross-linking cannot heal the ... Different types of contact lenses may be used to delay or eliminate the need for corneal transplantation in corneal disorders. ...
... has taken place since the 1960s, and is one of the largest organ transplant programmes in the ... "Human organ and tissue transplantation". WHO. Retrieved 23 September 2010.. *^ "Draft guiding principles on human organ ... a b HUMAN ORGAN TRANSPLANTATION - A Report on Developments Under the Auspices of WHO (1987-1991), page 7, World Health ... Peking University People's Hospital Liver Transplantation Center executed two cases of living related liver transplantation ...
Thymus transplantation[edit]. Thymus transplantation may be said to be able to cause a special type of GvHD because the ... Biology of Blood and Marrow Transplantation: Journal of the American Society for Blood and Marrow Transplantation. 22 (5): 910- ... "Biology of Blood and Marrow Transplantation. 11 (12): 945-956. doi:10.1016/j.bbmt.2005.09.004. PMC 4329079. PMID 16338616.. ... "Transplantation tolerance and autoimmunity after xenogeneic thymus transplantation". Journal of Immunology. 166 (3): 1843-1854 ...
Hair transplantation is a surgical technique that moves individual hair follicles from a part of the body called the donor site ... Hair transplantation differs from skin grafting in that grafts contain almost all of the epidermis and dermis surrounding the ... Rose, P. (2011). "The Latest Innovations in Hair Transplantation". Facial Plastic Surgery. 27 (4): 366-377. doi:10.1055/s-0031- ... "Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model". Science Advances. 2 (4 ...
During transplantation[edit]. While during infection T cell exhaustion can develop following persistent antigen exposure after ... Wells AD, Li XC, Strom TB, Turka LA (May 2001). "The role of peripheral T-cell deletion in transplantation tolerance". ... bone marrow transplantation, and HIV-1 infection". Annu. Rev. Immunol. 18: 529-60. doi:10.1146/annurev.immunol.18.1.529. PMID ... Biology of Blood and Marrow Transplantation. 24 (3): 618-622. doi:10.1016/j.bbmt.2017.11.022. PMID 29197679.. ...
a b c ABO Incompatible Heart Transplantation in Young Infants. (2009, July 30). ABO Incompatible Heart Transplantation in Young ... West, L. J. (2011). "ABO-incompatible hearts for infant transplantation". Current Opinion in Organ Transplantation. 16 (5): 548 ... "Pediatric Transplantation. 16 (1): 4-11. doi:10.1111/j.1399-3046.2011.01633.x. PMID 22248250.. ... "Nephrology, Dialysis, Transplantation. 16 (2): 355-60. doi:10.1093/ndt/16.2.355. PMID 11158412.. .mw-parser-output cite. ...
H-13, a new histocompatibility locus in the fifth linkage group". Transplantation. 5 (3): 492-503. doi:10.1097/00007890- ...
Patients after hematopoietic stem cell transplantation (HSCT) are at a higher risk for oral squamous cell carcinoma. Post-HSCT ... December 2010). "Oral cancer in patients after hematopoietic stem-cell transplantation: long-term follow-up suggests an ... increased risk for recurrence". Transplantation. 90 (11): 1243-4. doi:10.1097/TP.0b013e3181f9caaa. PMID 21119507. "Routine HPV ...
Transplantation. 17 (4): 346-354. doi:10.1097/00007890-197404000-00003. ISSN 0041-1337.. ...
... contain high levels of alpha GST and serum alpha GST has been found to be an indicator of hepatocyte injury in transplantation ... enables the measurement of urinary GSTs to be used to quantify and localise renal tubular injury in transplantation, ... to evaluate the clinical benefits of serum alpha-glutathione S-transferase concentration monitoring after liver transplantation ...
"Cause of atrioventricular block in patients after heart transplantation". Transplantation journal. "USC AGSA Dinner Dance and ... He co-authored a research article in the peer-reviewed journal Transplantation on "Cause of Atrioventricular Block in Patients ... After Heart Transplantation.". Margarian continued his education at the USC Marshall School of Business and received his MBA in ...
2019-03-19: Cell Transplantation. *2019-03-14: Journal of Speech, Language, and Hearing Research ...
"Calcineurin inhibitors in HLA-identical living related donor kidney transplantation". Nephrology, dialysis, transplantation : ... antibodies against human T cells which is used in the treatment of acute rejection in organ transplantation. Its use was first ... Transplantation Surgery. Springer Science & Business Media. p. 11. ISBN 9781447136897. Verghese, PS; Dunn, TB; Chinnakotla, S; ... "A comparison between ALG and bone marrow transplantation in treatment of severe aplastic anemia". Thymus. 10 (1-2): 147-58. ...
Yoshikawa, T (2003). "Human Herpesvirus-6 and -7 Infections in Transplantation". Pediatric Transplantation. 7 (1): 11-17. doi: ... American Journal of Transplantation. Blackwell Munksgaard. 4 Suppl 10: 66-71. 2004. doi:10.1111/j.1600-6135.2004.00697.x. PMID ...
Ultraviolet radiation is invisible to the human eye, but illuminating certain materials with UV radiation causes the emission of visible light, causing these substances to glow with various colors. This is called fluorescence, and has many practical uses. Black lights are required to observe fluorescence, since other types of ultraviolet lamps emit visible light which drowns out the dim fluorescent glow. Black light is commonly used to authenticate oil paintings, antiques and banknotes. Black lights can be used to differentiate real currency from counterfeit notes because, in many countries, legal banknotes have fluorescent symbols on them that only show under a black light. In addition, the paper used for printing money does not contain any of the brightening agents which cause commercially available papers to fluoresce under black light. Both of these features make illegal notes easier to detect and more difficult to successfully counterfeit. The same security features can be applied to ...
"Pancreas Transplantation". American Diabetes Association. Archived from the original on 13 April 2014. Retrieved 9 April 2014. ... sometimes requiring dialysis or kidney transplantation.[29] Damage to the nerves of the body, known as diabetic neuropathy, is ... including end stage kidney disease requiring kidney transplantation.[95] ...
Lung transplantation. Decortication of lung. Heart-lung transplant. Chest wall, pleura,. mediastinum,. and diaphragm. pleura/ ...
Schilsky ML (2013). "Hepatitis B "360"". Transplantation Proceedings. 45 (3): 982-985. doi:10.1016/j.transproceed.2013.02.099. ... Kerkar N (2005). "Hepatitis B in children: complexities in management". Pediatric transplantation. 9 (5): 685-691. doi:10.1111/ ... Terrault N, Roche B, Samuel D (July 2005). "Management of the hepatitis B virus in the liver transplantation setting: a ... Liver transplantation is sometimes used for cirrhosis.[1] ...
Zand, Martin S. (July 2013). "Tofacitinab in Renal Transplantation". Transplantation Reviews. 27 (3): 85-89. doi:10.1016/j.trre ... Myrvang, H (26 June 2012). "Transplantation: Tofacitinib safe and effective in renal transplant recipients". Nature Reviews. ... 245-. ISBN 978-1-118-88962-6. Wojciechowski, D; Vincenti, F (September 2013). "Tofacitinib in kidney transplantation". Expert ... World Journal of Transplantation. 2 (4): 51-68. doi:10.5500/WJT.v2.i4.51. PMC 3782235 . PMID 24175197. "FDA approves Xeljanz ...
Organ transplantation in different countries. *Organ transplantation in China. *Organ transplantation in Israel ...
Liver transplantation may be a valid option if no improvement occurs. If liver damage has progressed into fibrosis, ... Liver Transplantation. 12 (12): 1888-91. doi:10.1002/lt.21007. PMID 17133567. Gundermann KJ, Kuenker A, Kuntz E, Droździk M ( ...
... have been recognized by the National Library of Medicine as an authoritative source of patient information on transplantation, ... The American Society of Transplantation is an organization of professionals dedicated to advancing the field of transplantation ... Pediatric Kidney Transplantation: A Guide for Patients and Families (also available in Spanish version) ... Copyright © 2015 American Society of Transplantation. All Rights Reserved.. This website redesign was made possible in part by ...
28-З on transplantation of human organs and tissues of 4 March 1997 vis-à-vis its compliance with the Council of Europe ... The Additional Protocol to the Convention on Human Rights and Biomedicine, concerning Transplantation of Organs and Tissues of ... Additional Protocol to the Convention on Human Rights and Biomedicine, concerning Transplantation of Organs and Tissues of ... Human Origin contains general principles and specific provisions concerning transplantation. The Additional Protocol has been ...
2008). "Hand Transplantation: The Innsbruck Experience". Transplantation of Composite Tissue Allografts. pp. 234-250. doi: ... Hand transplantation is a surgical procedure to transplant a hand from one human to another. The "donor" hand usually comes ... On October 26, 2016, the Director of hand transplantation at UCLA, Dr. Kodi Azari, and his team,[14] performed a hand ... "Hand transplantation" - news · newspapers · books · scholar · JSTOR (April 2017) (Learn how and when to remove this template ...
The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update. J ... "A brief history of cross-species organ transplantation". Proc (Bayl Univ Med Cent). 25: 49-57. PMC 3246856. PMID 22275786.. ... Heart transplantation. Diagram illustrating the placement of a donor heart in an orthotopic procedure. Notice how the back of ... "LUNG TRANSPLANTATION". JAMA. 186: 1088. 1963. doi:10.1001/jama.1963.03710120070015.. in same issue. ...
Organ Donation and Transplantation Statistics (National Kidney Foundation) * The SRTR/OPTN Annual Data Report (Scientific ... Organ Transplantation: Frequently Asked Questions (United Network for Organ Sharing) * Partnering with Your Transplant Team: ... Organ Donation and Transplantation for Older Donors and Recipients: Resources from the U.S. Government (National Institute on ... Talking about Transplantation: What Every Patient Needs to Know (United Network for Organ Sharing) - PDF ...
Summary Table for Balamuthia Outbreaks Asociated with Organ Transplantation. Year(s). Donor. Transplant Recipients. Symptomatic ... Transmission of Balamuthia infection has occurred via organ transplantation from infected donors on three documented occasions ... Summary Table for Balamuthia Outbreaks Associated with Organ Transplantation in the United States. ...
Figure 1 , Bone Marrow Transplantation. Figure 1. From: Outcome after reduced-intensity conditioning allogeneic SCT for AML in ...
Demand for organ transplantation is increasing all over the world, but there are not enough organs available to meet the demand ... Demand for organ transplantation is increasing all over the world, but there are not enough organs available to meet the need. ... Find out all about donation and transplantation in your country and talk about your choice with your family, friends and ... The European Day for Organ Donation and Transplantation (EODD) aims to stimulate dialogue and encourage European citizens to ...
Lung Transplantation Lung transplantation research such as mechanisms of acute cellular and antibody-mediated rejection; ...
As a result of their input, we clarified several areas of the article relating to the outcomes of pancreas transplantation and ... 1Division of Transplantation Surgery, Mayo Clinic and Foundation, 200 First Street SW, Rochester, Minnesota 55902, USA. ... Successful pancreas transplantation provides durable glycemic control and improves survival for patients with diabetes. ... This review focuses on the outcomes of pancreas transplantation for patients with and without end stage renal disease. It ...
Definition Liver transplantation [2] is a surgery that removes a diseased liver and replaces it with a healthy donor liver. ... The disease reduces the livers ability to… Pancreas Transplantation , Pancreas Transplantation Definition Purpose Demographics ... Liver transplantation. Definition. Liver transplantation is a surgery that removes a diseased liver and replaces it with a ... Liver Transplantation. Definition. Liver transplantation is a surgery that removes a diseased liver and replace it with a ...
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The basic indication for a transplant is loss of vision due to corneal opacification - the inability to see through an injured or diseased cornea....
Transplantation of human organs and tissues, which saves many lives and restores essential functions for many otherwise ... Transplantation of human organs and tissues, which saves many lives and restores essential functions for many otherwise ... Ethics, access and safety in tissue and organ transplantation. Meeting report (2004). ...
... peer-reviewed journal covering all aspects of clinical and basic haemopoietic stem cell transplantation. ... Stem cell transplantation from identical twins in patients with myelodysplastic syndromes FREE. N Kröger, R Brand, A van Biezen ... Successful transplantation of peripheral blood stem cells mobilized by chemotherapy and a single dose of pegylated G-CSF in ... Hematopoietic stem cell transplantation in severe congenital neutropenia: experience of the French SCN register FREE. C Ferry, ...
Organ transplantation: an historical perspective. In: Hakim NS, Danovitch GM, editors. Transplantation surgery. London: ... International liver transplantation society 2009 presidential address: the internationalization of liver transplantation. Liver ... and transplantation of the kidney that preceded successful liver transplantation, and will describe the further evolution of ... The use of UW solution in clinical transplantation: a 4-year experience. Ann Surg. 1992;215(6):579-85.CrossRefGoogle Scholar ...
... handbook provides answers to important questions that may arise during the retrieval of multiple organs for transplantation and ... living donor kidney transplantation living donor liver transplantation multiple organ retrieval non-heart-beating donor organ ... Transplantation Bench Surgery of the Abdominal Organs Sguinzi Raffaella, Riccardo De Carlis, Maurizio Vertemati, Ornella ... Right Hemihepatectomy for Living Donor Liver Transplantation in Adults (Open Technique) Luciano De Carlis, Paolo Aseni, Stefano ...
We focus on immunology research and aim to develop new diagnostic tools and therapeutic interventions for immune-related diseases. ...
Central Concepts Underlying Islet Transplantation. The main idea of islet transplantation is to process the organ donors ... Pancreatic islet transplantation.. Naftanel MA1, Harlan DM.. Author information. 1. National Institute of Diabetes and ...
Survival After Islet Transplantation in Subjects With Type 1 Diabetes: Twenty-Year Follow-Up Joana R.N. Lemos, David A. Baidal ... Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. Diabetes Care 2016;39:1072-1074 David M. ... Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation in the United Kingdom Petros ... Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, ...
... number of transplantations carried out globally, access to transplantation, outcomes of transplantation. ... National transplantation organizations, as well as scientific and professional societies involved in transplantation, are ... Transplantation of human cells, tissues and organs. Service Delivery and Safety Health Systems and Innovation. World Health ... The provision of transplantation information is the proof of transparency and is essential in fostering public trust in the ...
Title: Handbook of Kidney Transplantation, Author: champmails32538, Name: Handbook of Kidney Transplantation, Length: 2 pages, ... E-book download Handbook of Kidney Transplantation {fulll,online,unlimite) KWH. E-book download Handbook of Kidney ...
PRNewswire/ -- announces that a new market research report is available in its catalogue: Transplantation ... Transplantation Global Clinical Trials Review, H1, 2013. Summary. GlobalDatas clinical trial report, Transplantation Global ... Transplantation Therapeutics Clinical Trials, Middle East and Africa, Top Five Countries, 2013* 14. Transplantation ... Transplantation Therapeutics Clinical Trials Market, Global, Clinical Trials by Kiadis Pharma B.V., 2013* 90. Transplantation ...
American Society of Transplantation. Screening of donor and recipient prior to solid organ transplantation. Am J Transplant ... Organ Procurement and Transplantation Network. Transplant data [Database]. Richmond, VA: Organ Procurement and Transplantation ... When transplantation-transmitted TB is suspected, health-care providers should alert the associated OPO, tissue bank, and ... Transplantation-Transmitted Tuberculosis --- Oklahoma and Texas, 2007. Approximately 28,000 organ transplants were performed in ...
Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts and will be automatically unlocked in 30 mins. For immediate assistance, contact Customer Service: 800-638-3030 (within USA), 301-223-2300 (international) [email protected] ...
International Liver Transplantation Society. Transplantation is proud to publish the Abstracts​ from the 27th International ... Global Transplantation COVID Report. Access the Global Transplantation COVID Report for global and regional updates on the ... Transplantations open access companion journal, Transplantation Direct, is open for submissions! ... Renal Transplantation in Mansoura, Egypt. Bakr, Mohamed A.; Shehab El-Dein, Ahmed B.; Refaie, Ayman F.; More ...
This policy statement is archived and no longer considered active ASAM policy. Archived statements are available for historical purposes upon request. Please email Susan Awad at [email protected] to request a copy of an archived policy statement ...
Source for information on Transplantation Genetics and Immunology: World of Microbiology and Immunology dictionary. ... Transplantation genetics and immunology There are several different types of transplantation. An autograft is a graft from one ... Transplantation genetics and immunology. There are several different types of transplantation. An autograft is a graft from one ... This is what is tested for when tissues are typed for transplantation. Most transplantation occurs with allogeneic organs, ...
Current research in Stem Cell Transplantation (SCT) focuses on improving transplant outcome through immune manipulations using ...
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  • Liver transplantation is a surgery that removes a diseased liver and replaces it with a healthy donor liver. (
  • Patients with advanced heart and lung disease, who are human immunodeficiency virus (HIV) positive, and who abuse drugs and alcohol are poor candidates for liver transplantation. (
  • Cirrhosis, a disease that kills healthy liver cells, replacing them with scar tissue, is the most common reason for liver transplantation in adults. (
  • Cirrhosis is the most common reason for liver transplantation in adults and is often a result of alcoholism. (
  • During a liver transplantation the sick liver is removed and subsequently replaced with a healthy donor liver. (
  • A liver transplantation team consists of gastroenterologists, transplantation surgeons, anaesthetists, nurse specialists and physician assistants. (
  • When the team recommends a liver transplantation and you agree, you will be put on a Eurotransplant waiting list. (
  • After the liver transplantation you stay at the LUMC for about three weeks. (
  • If you decide to get a liver transplantation, you will be put on the Eurotransplant waiting list. (
  • Liver transplantation has evolved rapidly from an experimental procedure to standard therapy for patients with end-stage liver disease. (
  • The relative shortage of donor organs provides the basis for many of the ethical issues associated with liver transplantation. (
  • Liver Transplantation is the official journal of AASLD. (
  • The next Liver Transplantation Journal Club Twitter chat is Tuesday, December 11 at 7 pm EST. (
  • To participate, follow the Liver Transplantation journal on Twitter. (
  • By visiting Liver Transplantation one can find the latest research findings, relevant scientific data, and the Journals EarlyView (articles in advance of print). (
  • Readers may view the full-text articles in Liver Transplantation Online including an electronic back-file dating back to 1995. (
  • Members - As an AASLD member subscriber to HEPATOLOGY and/or Liver Transplantation , a Wiley InterScience (WIS) account has been created for you to access the journal(s) online. (
  • Direct all comments about Liver Transplantation to Karey Martinez at [email protected] . (
  • The Liver Transplantation Journal Club kicks off on August 15 with a moderated Twitter discussion on the pros and cons of steroid weaning in transplant recipients with autoimmune hepatitis. (
  • The National Institutes of Health announced the launch of the HOPE in Action Multicenter Liver Study, designed to evaluate liver transplantation outcomes in patients with HIV, according to a recent press release. (
  • This unique characteristic has made the living donor liver transplant as an alternative to deceased donor liver transplantation. (
  • The first part comprises of the risk due to liver transplantation surgery itself while the other part includes the risk and side effects due to potent medications. (
  • Types of Liver Transplantation in India. (
  • The Liver Transplantation SIG provides a forum within AASLD for the exploration of topics of common interest to hepatologists, surgeons and other health care professionals with a primary interest in liver transplantation and hepatobiliary surgery. (
  • The authors present an extremely challenging case of en bloc heart and liver transplantation in a patient with severe heart and liver failure due to failing Fontan circulation. (
  • Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. (
  • As a result, although the risk of transmission of Naegleria fowleri by donor organs is still unknown, it is unlikely to be zero so the risks of transplantation with an organ possibly harboring Naegleria fowleri should be carefully weighed for each individual organ recipient against the potentially greater risk of delaying transplantation while waiting for another suitable organ. (
  • Use of organs for transplantation from a donor with primary meningoencephalitis due to Naegleria fowleri . (
  • Heterotrophic transplantation- The addition of a donor liver at another site, while the diseased liver is left intact. (
  • Nonetheless, the replacement of diseased organs by transplantation of healthy tissues has frustrated medical science because the immune system of the recipient recognizes that the donor organ is not "self" and rejects the new organ. (
  • Organ transplantation is surgery in which a diseased or damaged organ is removed from a patient and replaced with a healthy organ from an organ donor. (
  • Although rejection of the transplanted organ by the immune system of the recipient (immunologic rejection) is a major problem in the field of organ transplantation, an even bigger challenge is the shortage of donor organs. (
  • Graft rejection occurs in 5-30% of patients, a complication possible with anyprocedure involving tissue transplantation from another person (allograft).Allograft rejection results from a reaction of the patient's immune system tothe donor tissue. (
  • In patients withthese conditions, careful testing of both donor and recipient is performed just as in transplantation of other organs and tissues such as hearts, kidneys,and bone marrow. (
  • Increasing numbers of patients are referred for transplantation, but there has been no concomitant increase in the supply of kidneys from the traditional cadaveric donor pool. (
  • Clearly, therefore, the full potential of renal transplantation will be realised only if other donor sources can be developed. (
  • [ 4 ] However, the rate of living-donor transplants began to decline in 2004 and has reached a plateau representing approximately 30% of all kidney transplantations. (
  • Heart transplantation is considered the gold-standard therapy for end-stage systolic heart failure but the shortage of donor hearts in Germany and other countries has led to widespread use of left ventricular assist devices (LVAD). (
  • While the graft-versus-tumor effect provided by the donor graft can be very powerful in controlling the disease, disease relapse is still the primary reason that patients do not do well after an allogeneic transplantation. (
  • Transplantation is a progressive process requiring hundreds of micro-grafts, each of which will generally contain from one to three hairs mini-grafted from a donor site on the side or back of the head. (
  • The Eye Bank Association of America procures, prepares, and distributes donor corneal tissue for transplantation. (
  • A small number of people with Type 1 diabetes can benefit from islet transplantation, a procedure in which an individual's destroyed islet cells are replaced using cells harvested from donor pancreases. (
  • Allogeneic stem cell transplantation (infusion of donor stem cells into a patient) is the best-documented curative treatment for select patients with CML at this time. (
  • Paired donor exchange kidney transplantation is a process in which unrelated kidney donors are matched to recipients so that compatible transplants can be performed. (
  • To investigate this, scientists can use a classic technique known as transplantation, which involves tissue from a donor embryo being excised and grafted into a host embryo. (
  • Finally, some specific developmental studies utilizing this technique are discussed, which examine the effect of tissue transplantation on the fate of donor and host tissue. (
  • The aim of this review is to outline a contemporary perspective on cardiac transplantation with respect to recipient and donor management, as well as an appropriate organisational policy. (
  • The other trend is that outcomes after cardiac transplantation have not consistently improved, due to listing of more critically ill patients, use of so-called marginal donor hearts from an extended donor pool, 1 and the initiation of new heart transplantation centres with an inevitable learning phase. (
  • Kidney transplantation is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantation depending on the source of the donor organ. (
  • Until the routine use of medications to prevent and treat acute rejection, introduced in 1964, deceased donor transplantation was not performed. (
  • GKT1 activities and practices in allogeneic transplantation: number of transplantations carried out globally, access to transplantation, outcomes of transplantation. (
  • GKT2 legal framework and organizational structures of allogeneic transplantation. (
  • Most transplantation occurs with allogeneic organs, which by definition are those that do not share the same MHC locus. (
  • Please go to NICE interventional procedure guidance 257 to view the full guidance on allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus and to NICE interventional procedure guidance 274 to view the full guidance on autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy issued to the NHS in England, Wales, Scotland and Northern Ireland. (
  • While allogeneic transplantation can be life saving for patients with hematologic malignancies, or inherited disorders such as several forms of immuno-deficiency, the transplant-related side effects and complications remain the biggest hurdles. (
  • The decision to pursue allogeneic transplantation has become more complicated because many patients have very good responses to TKIs. (
  • A doctor will consider many important factors when deciding if an allogeneic transplantation is the preferred choice of treatment for a patient. (
  • This review focuses on the outcomes of pancreas transplantation for patients with and without end stage renal disease. (
  • Formal seminars and journal clubs in renal transplantation have been incorporated into the year-round schedule. (
  • The resident should be able to discuss the relative and absolute contraindications to renal transplantation. (
  • Renal transplantation has become a victim of its own success. (
  • Kidney transplantation is the treatment of choice for a minority of patients with end-stage renal disease (ESRD). (
  • Indications for kidney transplantation include chronic kidney disease (CKD) and renal tumors. (
  • Background: Simultaneous pancreas- kidney transplantation (SPK) is an established therapy for diabetes mellitus (DM) patients with associated end stage renal disease. (
  • Updated to reflect todays practice guidelines, the new edition of this comprehensive text remains the definitive resource on all aspects of renal transplantation, including immunological, pathological, psychological and ethical considerations. (
  • There are comprehensive chapters on pediatric renal transplantation and on renal transplantation in the developing world. (
  • Kidney transplantation or renal transplantation is the organ transplant of a kidney into a patient with end-stage renal disease . (
  • In this chapter I sketch relevant aspects of the landscape that formed the background for my ethnographic field research in the Institute on live, related, renal transplantation in 2002. (
  • The study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and follows the launch of a similar study for kidney transplantation outcomes in patients with HIV launched in 2018. (
  • There have been many advances in solid organ transplantation over the years that have made these medications quite tolerable. (
  • Transmission of Balamuthia mandrillaris through solid organ transplantation: utility of organ recipient serology for guide clinical management. (
  • Cite this: Palliative Care in Solid Organ Transplantation - Medscape - Dec 08, 2015. (
  • The most sensitive type of transplantation with respect to this are those involving the bone marrow (Haematopoietic Stem Cell Transplantation) HLA matching is an absolute requirement so its use is limited to HLA-matched donors, usually a brother or sister. (
  • The main idea of islet transplantation is to process the organ donor's pancreas so as to remove the 95% of the gland responsible for its exocrine functions (secretion of digestive enzymes) and isolate the 5% of the gland responsible for the endocrine hormone secretion- the so-called pancreatic islets. (
  • Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. (
  • Islet cell transplantation is an attractive alternative therapy to conventional insulin treatment or vascularized whole pancreas transplantation for type 1 diabetic patients. (
  • Improved control of glycated HbA1c, reduced risk of recurrent hypoglycemia and of diabetic complications are also seen as important benefits of islet cell transplantation, irrespective of the status of insulin independence. (
  • NICE's guidance on pancreatic islet cell transplantation has now been replaced. (
  • Islet transplantation can temporarily cure type 1 diabetes mellitus (T1DM) but requires simultaneous immunosuppression to avoid allograft rejection. (
  • Clinical islet transplantation is gaining acceptance as a potential therapy, particularly for subjects who have labile diabetes or problems with hypoglycemic awareness. (
  • We have performed 54 islet transplantation procedures on 30 subjects and have detailed follow-up in 17 consecutive Edmonton protocol-treated subjects who attained insulin independence after transplantation of adequate numbers of islets. (
  • Our results, with a maximum follow-up of 34 months, indicate that prolonged insulin independence can be achieved after islet transplantation. (
  • Islet transplantation is a reasonable option in those with severe problems with glycemic lability or hypoglycemia. (
  • Interest in islet transplantation has increased enormously, because of the improved success rates with newer immunosuppressive regimens and islet preparation techniques ( 1 , 2 ). (
  • The early promise of islet transplantation is now a reality, but the process still carries potential risks. (
  • Islet cell transplantation can be life-changing for a small number of people with Type 1 diabetes and getting it to this stage would not have been possible without the collaborative efforts of all the dedicated researchers and doctors involved. (
  • Although the clinical practice of organ transplantation is only a few decadesold, attempts to replace a failing organ with a healthy one have occurred for centuries, and mythic literature often describes it as a cure for disease.The first successful organ transplant was a kidney transplant performed in 1954 in Boston, Massachusetts. (
  • The University of Alberta has an active multi-organ transplant program resulting in the transplantation of approximately 70 kidney, 5-8 simultaneous pancreas-kidney, 45 liver, 40 heart, heart-lung, or lung transplants each year. (
  • This includes all adult patients admitted for kidney transplantation and patients readmitted with transplant-specific complications. (
  • Belatacept May Change Kidney Transplantation Medicine - Medscape - Mar 30, 2010. (
  • Kidney transplantation is the treatment of choice for most patients with stage five chronic kidney disease (CKD). (
  • The journal aims to bring to its readers essential experienced insights and reviews regarding liver, kidney, bone marrow, heart and lung transplantations. (
  • Marked improvements in early graft survival and long-term graft function have made kidney transplantation a more cost-effective alternative to dialysis. (
  • Before the advent of immunosuppression , kidney transplantation was limited to identical twins and was not applicable to the vast majority of patients with ESRD. (
  • Studies show that kidney transplantation prolongs patient lifespan compared with dialysis. (
  • This 6th edition remains the balanced reference you need to stay apprised of issues important to successful kidney transplantation. (
  • The major barrier to organ transplantation between genetically non-identical patients lay in the recipient's immune system, which would treat a transplanted kidney as a "non-self" and immediately or chronically reject it. (
  • In March 1993, NIH published interim guidelines for research involving human fetal tissue transplantation. (
  • These guidelines were based on the recommendations of the 1988 Human Fetal Tissue Transplantation Research Panel and were designed to ensure that Federal funding of human fetal tissue transplantation research would not encourage the choice of abortion. (
  • On June 10, 1993, the NIH Revitalization Act of 1993 (Public Law 103-43) was enacted, and, because of the superseding provisions contained in the law regarding fetal tissue transplantation, the interim guidelines were withdrawn. (
  • [2] Heart transplantation is not considered to be a cure for heart disease but a life-saving treatment intended to improve the quality of life for recipients. (
  • Organ transplantation from donors infected by Naegleria fowleri has occurred on at least five occasions in the U.S. and none of the organ recipients became infected 1-3 . (
  • The GKT will be a source of information for all involved from the lay public, whose willingness to donate relies on an understanding of the value of transplantation and who might some day benefit as a recipient, to health professionals and health authorities responsible for the success, safety and quality of cell, tissue and organ transplantation, while maintaining the dignity of donors and recipients. (
  • In a report from the U.S. Department of Health and Human Services in December 1997, the one-year and three-year survival rates for organ transplantation recipients had reached an all-time high. (
  • Lung transplant recipients have the highest incidence of infections and present the greatest diagnostic challenges among organ transplantation patients. (
  • This and several other studies revealed that survival rates vary between transplantation centers. (
  • The LUMC is one of the three Dutch university medical centers where liver transplantations are performed. (
  • While solid-organ transplants are common at UCLA and other major medical centers, reconstructive transplantation -- a complex surgery involving a variety of tissues (including bones, tendons, arteries and nerves) -- marks a new direction for the field. (
  • The preferred preparative regimen for specific diseases and the approaches to prevention of the other major complications of hematopoietic cell transplantation (eg, graft-versus-host disease) are discussed separately. (
  • See 'Hematopoietic cell transplantation for primary immunodeficiency' . (
  • The Meyer Lab studies how T-cells and invariant NKT facilitate immune tolerance and graft-versus-leukemia effects in the setting of hematopoietic cell transplantation. (
  • To receive news and publication updates for Journal of Transplantation, enter your email address in the box below. (
  • Indian Journal of Transplantation is the official journal of the Indian Society of Organ Transplantation with Editorial Office situated at Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow. (
  • The European Day for Organ Donation and Transplantation (EODD) aims to stimulate dialogue and encourage European citizens to say yes to organ, tissue and cell donation. (
  • Find out all about donation and transplantation in your country and talk about your choice with your family, friends and colleagues! (
  • Through the GKT, the World Health Organization aims to bring together in one database information on organ, tissue and cell donation and transplantation from around the world. (
  • The first two components, GKT1 and 2 lead to a global database that is in the Global Observatory on Donation and Transplantation (GODT). (
  • Successful pancreas transplantation provides durable glycemic control and improves survival for patients with diabetes. (
  • It describes the current state of pancreas transplantation, gaps in knowledge, and future studies needed to enable more patients to benefit from this treatment. (
  • A common theme that emerges is the need for multicenter randomized trials in pancreas transplantation to define clearly the efficacy, risks, and long term benefits. (
  • They were asked about how they came to consider pancreas transplantation and their perceptions of insulin therapy compared with pancreas transplantation. (
  • As a result of their input, we clarified several areas of the article relating to the outcomes of pancreas transplantation and alternative therapies. (
  • Details how the factors that drove clinical use of high-dose chemotherapy with autologous bone marrow transplantation (HDC/ABMT)-patient demand, physician enthusiasm, media reporting, litigation, and administrative mandates-converged to propel the procedure forward despite a lack of proven clinical effectiveness. (
  • Transplantation of human organs and tissues, which saves many lives and restores essential functions for many otherwise untreatable patients, both in developing and developed countries, has been a topic for ethical scrutiny and health care policy-making for more than thirty years. (
  • The second stage of infectious risk following transplantation extends from 1 to 6 months, which is the period of maximum sustained immunosuppression in order to minimize acute allograft rejection.6 The patients are often discharged into their normal environment and the risk of bacterial pneumonia subsides. (
  • Most adult patients with ESRD are never referred for evaluation for transplantation, and have a 70% 5-year mortality on dialysis. (
  • however, no previous report has addressed, in a large and appropriately annotated and followed multicenter population, potential distinct survival profiles of transplant glomerulopathy patients with different underlying pathogeneses," Olivier Aubert, MD, PhD, of the Paris Translational Research Center for Organ Transplantation, and colleagues wrote. (
  • Objective: To evaluate the effects of an early-based cardiac rehabilitation program on the functional capacity, inspiratory muscular strength and clinical outcomes in hospitalized heart failure patients before and after heart transplantation. (
  • Patients undergoing cardiac transplantation will be enrolled in the study after giving a written, signed informed consent. (
  • Following heart transplantation patients will undergo HCV antibody, virus PCR, and liver function testing. (
  • This means that a substantial fraction of patients transplanted during childhood fail to survive to adulthood, or require heart re-transplantation, because of complications related to heart transplant. (
  • The UCLA face transplantation team recognizes the sensitivity required when it comes to working with patients who have experienced a severe facial disfigurement. (
  • Meniscal transplantation (replacement or reconstruction) is gaining popularity in the treatment of patients under age 50 with early evidence of post-traumatic arthritis. (
  • At Cleveland Clinic, we reserve meniscal transplantation for minimally to moderately symptomatic patients with large, irreparable tears. (
  • Appropriate candidates for transplantation include patients with stable, well-aligned knees and minimal to moderate symptomatic, post-traumatic arthritis. (
  • After transplantation, patients are monitored for about 3-4 weeks, during which time they receive antibiotics and transfusions to aid recovery. (
  • Physically severely ill patients associate their organ transplantation procedure with their hopes for health and wellbeing. (
  • Studies have shown that stem cell transplantation could aid in the restoration of brain function in patients with medical conditions such as Parkinson's and Huntington's diseases, and stroke. (
  • On the one hand, transplantation has a proven curative track record for some CML patients. (
  • The death rates of advanced heart failure patients on the waiting list of the United Network for Organ Sharing (UNOS), the US organisation in charge of organ transplantation ( ), have decreased dramatically over time, from 432.2 per 1000 patient years in 1990 to 172.4 per 1000 patient years in 1999. (
  • Genomic screening and complications of hematopoietic stem cell transplantation: has the time come? (
  • Current research in Stem Cell Transplantation (SCT) focuses on improving transplant outcome through immune manipulations using cell therapy and lymphocyte growth factors. (
  • What is hematopoietic stem cell transplantation? (
  • Hematopoietic stem cell transplantation was first used as a treatment for some types of cancer but is now widely used as a therapy for various autoimmune diseases. (
  • It is important to note, however, that while the United States Food and Drug Administration (FDA) have approved hematopoietic stem cell transplantation (HSCT) for use against cancer , it is not yet approved for wider use. (
  • Features peer-reviewed articles covering all aspects of clinical and basic hemopoietic stem cell transplantation. (
  • Cell Transplantation publishes original, peer-reviewed research and review articles on the subject of cell transplantation and its application to human diseases. (
  • To provide complete coverage of this revolutionary field, Cell Transplantation will report on relevant technological advances, and ethical and regulatory considerations of cell transplants. (
  • Cell Transplantation is now an Open Access journal starting with volume 18 in 2009, and therefore there will be an inexpensive publication charge, which is dependent on the number of pages, in addition to the charge for color figures. (
  • Cell Transplantation is now being published by SAGE. (
  • This finding sheds light on how the body responds to injury and has implications for blood cell transplantation. (
  • Meloxicam in combination with G-CSF may improve the success rates of blood stem cell transplantation by making it easier to obtain sufficient numbers of cells for transplant. (
  • All aspects of organ, tissue and cell transplantation clinically and experimentally. (
  • Create healthcare diagrams like this example called Leukemia - Stem Cell Transplantation in minutes with SmartDraw. (
  • The purpose of the CIRM Stem Cell Transplantation Immunology Awards is to fund transformative research leading to the development of immune tolerance of pluripotent stem cell derivatives and potential correction of autoimmunity. (
  • Submission of an application for the Stem Cell Transplantation Immunology RFA involves a two-step process in which an applicant first submits a Letter of Intent (LOI). (
  • The application for the Stem Cell Transplantation immunology Award consists of four parts: Part A: Application Information Form, Part B: Stem Cell Transplantation Immunology Award Research Proposal, Part C: Biographical Sketches for Key Personnel, and Part D: Related Business Entities Disclosure Form. (
  • All four parts of the application for Stem Cell Transplantation Awards must be submitted together and received by CIRM no later than 5:00pm PST on January 26, 2010 , in both electronic form and in hard copy (a signed original and five copies). (
  • Could stem cell transplantation yield a cure for MS? (
  • The groundbreaking treatment being trialed is called autologous hematopoietic stem cell transplantation (AHSCT) - a procedure that is currently used to treat cancers of the bone and blood, such as leukemia and multiple myeloma . (
  • Unfortunately, the problem of the practice of unsupervised and/or untrained hair transplantation is increasing at a rapid pace. (
  • This is a natural evolution,' said Steve Stickney, Hair Club's vice president of the Central Region, 'Hair Club has been offering cutting-edge services for 32 years, and now we've reached a level of technological advancement where hair transplantation offers phenomenal results. (
  • With the hair transplantation option, area customers will save a lot of time. (
  • We have a very seasoned, experienced group of professionals there, most capable of helping clients with whatever solution they choose for their hair loss, whether it's hair transplantation surgery, Non-Surgical Bio-Matrix® hair replacement, or EXT (Extreme Hair Therapy),' Steve Stickney said. (
  • Micro-hair transplantation is a state-of-the-art hair transplantation technique that has replaced 'plugs' or larger grafts of hair. (
  • One of the first mentions of the possibility of heart transplantation was by American medical researcher Simon Flexner , who declared in a reading of his paper on "Tendencies in Pathology" in the University of Chicago in 1907 that it would be possible in the then-future for diseased human organs substitution for healthy ones by surgery - including arteries, stomach, kidneys and heart. (
  • Transplantation surgery is performed with general anesthesia, using an incision on the side of the chest for single lung transplantation or across the sternum or breastbone for double and heart-lung transplantation. (
  • Dr. Gerald Lipshutz , medical director of the new face transplantation program and associate professor of surgery and medicine at the Geffen School of Medicine, noted that face transplantation is still considered experimental and is not without risk. (
  • Bivalirudin resistance during heart transplantation surgery. (
  • In the United States alone, greater than 20,000 organ transplantations are performed annually, and approximately 2,300 of these are heart transplants. (
  • By the late 1990s, more than 2,300 heart transplants were performed annuallyin the United States alone, not to mention the transplantation of other organs. (
  • The Additional Protocol to the Convention on Human Rights and Biomedicine, concerning Transplantation of Organs and Tissues of Human Origin contains general principles and specific provisions concerning transplantation. (
  • This is what is tested for when tissues are typed for transplantation. (
  • We also study T cell immune reconstitution following transplantation and in graft-versus host disease with emphasis on clinical trial biomonitoring. (
  • I thought you might be interested in this item at Title: Bone marrow transplantation. (
  • Add tags for "Bone marrow transplantation. (
  • Bone marrow transplantation (BMT) using HSC is an increasingly common. (
  • We investigated the graft-protective effect of a kind of statin, Pravastatin, in the survival of fully MHC-mismatched murine cardiac allograft transplantation. (
  • This video demonstrates a "split-graft technique" for heart transplant following a hybrid bridge to transplantation approach in a neonate with an underlying diagnosis of aortic atresia and hypoplastic arch. (
  • In this interview, Shruti Jayakumar speaks with Kumud Dhital about advances in cardiac transplantation. (
  • In parallel, research w2-5 has led to the concept of cardiac replacement by transplantation. (
  • 300 in the UK, it is evident that cardiac transplantation will continue to play only a very limited quantitative role in the treatment of the advanced heart failure syndrome. (
  • One of the biggest obstacles yet to be overcome in organ transplantation is immunologic rejection, an automatic response by the immune system of the recipient that attacks and destroys the "foreign" tissue of the new organ. (
  • Although this therapy improved the results of transplantation, acute rejection and complications associated with steroid therapy persisted. (
  • The HMG-CoA reductase inhibitor (Statin), which reduces serum cholesterol has been demonstrated in the control of immune responses and may potential play an important role in the regulation of acute and chronic rejection in organ transplantations. (
  • After a transplantation procedure, the fear of transplant rejection and failure is a stressor that can trigger anxiety related and depressive adjustment disorders after the operation. (
  • In autologous transplantation, doctors usually collect, or harvest, stem cells that circulate in the bloodstream. (
  • The timing and site of transplantation can affect the stem cells' migration and differentiation, however. (
  • Researchers have demonstrated MR imaging of stem cells labeled with superparamagnetic iron oxide nanocomposites to track the cells after transplantation to aid in the restoration of brain function. (
  • For more information, see About Corneal Transplantation , American Academy of Ophthalmology. (
  • The least sensitive are corneal lens transplantation, probably because of lack of vascularisation in the cornea and its relative immunological privilege. (
  • TABLE 1 lists common conditions that cause corneal blindness and may necessitate corneal transplantation. (
  • Corneal transplantation involves removing the diseased cornea and replacing it with a new cornea (from a cadaver). (
  • Corneal transplantation is common in the United States, with about 40,000 procedures done each year. (
  • Performed when the eye disease cannot be treated noninvasively, corneal transplantation is usually indicated to restore vision. (
  • The American Society of Transplantation is an organization of professionals dedicated to advancing the field of transplantation and improving patient care by promoting research, education, advocacy, and organ donation. (
  • In this paper we review the current body of literature regarding the use of this biological agent in the field of transplantation. (
  • Transplantation raises a number of bioethical issues, including the definition of death, when and how consent should be given for an organ to be transplanted, and payment for organs for transplantation. (
  • This work is based on a selected review of the relevant medical and scientific literature, with emphasis on lung transplantation experience gained during 2 decades of practice. (
  • Lung transplantation has been provided at Cedars-Sinai Medical Center since 1988, when the Center was the first of its kind in the western United States. (
  • There are recommended age limitations: single lung transplantation is recommended for individuals who are under 75 years of age, double lung transplantation for those under 65 and heart-lung transplantation for those under 60. (
  • Therefore, to optimize clinical transplantation paradigms, researchers will need to monitor the cells' migration over time to determine the optimal parameters for transplantation. (
  • Hand transplantation is a surgical procedure to transplant a hand from one human to another. (
  • LOS ANGELES , May 25, 2012 /PRNewswire-USNewswire/ --The UCLA Health System has launched the UCLA Face Transplantation Program, the first surgical program of its kind in the western United States and one of only a handful in the nation. (
  • Following the first successful heart transplantation in 1967 in the Groote-Schuur-Hospital, Kapstadt, South Africa, w6 the first successful US heart transplant was performed in 1968 at Stanford University. (
  • These brochures have been recognized by the National Library of Medicine as an authoritative source of patient information on transplantation, . (
  • In addition to the organ pathology following organ transplantation that is described in the article, allotransplantation may be associated with a multitude of psychological stress reactions and disorders. (