Individuals connecting by family, work or other interests. It also includes connectivity facilitated by computer-based communications.
How information is gathered in personal, academic or work environments and the resources used.
The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.
The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Research that involves the application of the natural sciences, especially biology and physiology, to medicine.
Financial support of research activities.
Usually refers to planned scientific data-gathering excursions.
The moral obligations governing the conduct of research. Used for discussions of research ethics as a general topic.
Those individuals engaged in research.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.
The use of humans as investigational subjects.
A formal process of examination of patient care or research proposals for conformity with ethical standards. The review is usually conducted by an organized clinical or research ethics committee (CLINICAL ETHICS COMMITTEES or RESEARCH ETHICS COMMITTEES), sometimes by a subset of such a committee, an ad hoc group, or an individual ethicist (ETHICISTS).
Time period from 1901 through 2000 of the common era.
Human experimentation that is not intended to benefit the subjects on whom it is performed. Phase I drug studies (CLINICAL TRIALS, PHASE I AS TOPIC) and research involving healthy volunteers are examples of nontherapeutic human experimentation.
Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Difficult or labored breathing.
Organized groups serving in advisory capacities related to health planning activities.
Research carried out by nurses, generally in clinical settings, in the areas of clinical practice, evaluation, nursing education, nursing administration, and methodology.
Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.
The integration of epidemiologic, sociological, economic, and other analytic sciences in the study of health services. Health services research is usually concerned with relationships between need, demand, supply, use, and outcome of health services. The aim of the research is evaluation, particularly in terms of structure, process, output, and outcome. (From Last, Dictionary of Epidemiology, 2d ed)
Hospital or other institutional committees established to protect the welfare of research subjects. Federal regulations (the "Common Rule" (45 CFR 46)) mandate the use of these committees to monitor federally-funded biomedical and behavioral research involving human subjects.
Persons who are enrolled in research studies or who are otherwise the subjects of research.
Human experimentation that is intended to benefit the subjects on whom it is performed.
An international agreement of the World Medical Association which offers guidelines for conducting experiments using human subjects. It was adopted in 1962 and revised by the 18th World Medical Assembly at Helsinki, Finland in 1964. Subsequent revisions were made in 1975, 1983, 1989, and 1996. (From Encyclopedia of Bioethics, rev ed, 1995)
Disease involving the RADIAL NERVE. Clinical features include weakness of elbow extension, elbow flexion, supination of the forearm, wrist and finger extension, and thumb abduction. Sensation may be impaired over regions of the dorsal forearm. Common sites of compression or traumatic injury include the AXILLA and radial groove of the HUMERUS.
Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Committees established by professional societies, health facilities, or other institutions to consider decisions that have bioethical implications. The role of these committees may include consultation, education, mediation, and/or review of policies and practices. Committees that consider the ethical dimensions of patient care are ETHICS COMMITTEES, CLINICAL; committees established to protect the welfare of research subjects are ETHICS COMMITTEES, RESEARCH.
A publication issued at stated, more or less regular, intervals.
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
Time period from 2001 through 2100 of the common era.
Informed consent given by a parent on behalf of a minor or otherwise incompetent child.
Administrative units of government responsible for policy making and management of governmental activities.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Committees of professional personnel who have responsibility for determining policies, procedures, and controls related to professional matters in health facilities.
The principles of professional conduct concerning the rights and duties of the physician, relations with patients and fellow practitioners, as well as actions of the physician in patient care and interpersonal relations with patient families.
Confidence in or reliance on a person or thing.
The study of the social determinants and social effects of health and disease, and of the social structure of medical institutions or professions.
Occupations of medical personnel who are not physicians, and are qualified by special training and, frequently, by licensure to work in supporting roles in the health care field. These occupations include, but are not limited to, medical technology, physical therapy, physician assistant, etc.
Individual's rights to obtain and use information collected or generated by others.
A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Any type of research that employs nonnumeric information to explore individual or group characteristics, producing findings not arrived at by statistical procedures or other quantitative means. (Qualitative Inquiry: A Dictionary of Terms Thousand Oaks, CA: Sage Publications, 1997)
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
Facilities that collect, store, and distribute tissues, e.g., cell lines, microorganisms, blood, sperm, milk, breast tissue, for use by others. Other uses may include transplantation and comparison of diseased tissues in the identification of cancer.
An enduring, learned predisposition to behave in a consistent way toward a given class of objects, or a persistent mental and/or neural state of readiness to react to a certain class of objects, not as they are but as they are conceived to be.
Research carried out by nurses in the clinical setting and designed to provide information that will help improve patient care. Other professional staff may also participate in the research.
Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.
An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
The branch of mathematics dealing with the purely logical properties of probability. Its theorems underlie most statistical methods. (Last, A Dictionary of Epidemiology, 2d ed)
Experimentation on STEM CELLS and on the use of stem cells.
The study of natural phenomena by observation, measurement, and experimentation.
The privacy of information and its protection against unauthorized disclosure.
Multiple symptoms associated with reduced oxygen at high ALTITUDE.
The study of laws, theories, and hypotheses through a systematic examination of pertinent facts and their interpretation in the field of dentistry. (From Jablonski, Illustrated Dictionary of Dentistry, 1982, p674)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Time period from 1701 through 1800 of the common era.
Health care professionals, technicians, and assistants staffing LABORATORIES in research or health care facilities.
A situation in which an individual might benefit personally from official or professional actions. It includes a conflict between a person's private interests and official responsibilities in a position of trust. The term is not restricted to government officials. The concept refers both to actual conflict of interest and the appearance or perception of conflict.
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.

Is translational research compatible with preclinical publication strategies? (1/1209)

The term "translational research" is used to describe the transfer of basic biological knowledge into practical medicine, a process necessary for motivation of public spending. In the area of cancer therapeutics, it is becoming increasingly evident that results obtained in vitro and in animal models are difficult to translate into clinical medicine. We here argue that a number of factors contribute to making the translation process inefficient. These factors include the use of sensitive cell lines and fast growing experimental tumors as targets for novel therapies, and the use of unrealistic drug concentrations and radiation doses. We also argue that aggressive interpretation of data, successful in hypothesis-building biological research, does not form a solid base for development of clinically useful treatment modalities. We question whether "clean" results obtained in simplified models, expected for publication in high-impact journals, represent solid foundations for improved treatment of patients. Open-access journals such as Radiation Oncology have a large mission to fulfill by publishing relevant data to be used for making actual progress in translational cancer research.  (+info)

Telomerase immunity from bench to bedside: round one. (2/1209)

Telomerase, a reverse transcriptase primarily devoted to the elongation of telomeres in mammalian cells, is also the first bona fide common tumor antigen. In fact, telomerase is over-expressed in > 85% of tumor cells irrespective of origin and histological type. In the past seven years, there has been considerable interest in assessing telomerase as substrate for vaccination in cancer patients to induce CD8 T cell responses. Because the activation of T cells is restricted by the MHC molecules on antigen presenting cells or tumor cells, the identification of telomerase peptides immunogenic for humans is tightly linked with HLA types. To date, a handful of peptides have been identified through a variety of screening procedures, including bioinformatics prediction, in vivo immunization of HLA transgenic mice, in vitro immunization of PBMC from normal donors and cancer patients, and processing in human tumor cells. Currently, there exist putative peptides for five major HLA types (A2, A1, A3, A24 and B7). Due to the complexity of the HLA system, trials have been performed focusing on the most prevalent HLA type, HLA-A2. Here, we summarize this collective effort and highlight results obtained in Phase 1 trials including a Phase 1 trial performed at the UCSD Cancer Center.  (+info)

In support of descriptive studies; relevance to translational research. (3/1209)

The contemporary scientific establishment equates hypothesis testing to good science. This stance bypasses the preliminary need to identify a worthwhile hypothesis through rigorous observation of natural processes. If alleviation of human suffering is claimed as the goal of a scientific undertaking, it would be unfair to test a hypothesis whose relevance to human disease has not been satisfactorily proven. Here, we argue that descriptive investigations based on direct human observation should be highly valued and regarded essential for the selection of worthwhile hypotheses while the pursuit of costly scientific investigations without such evidence is a desecration of the cause upon which biomedical research is grounded.  (+info)

Supporting the design of translational clinical studies through the generation and verification of conceptual knowledge-anchored hypotheses. (4/1209)

The ability to generate hypotheses based upon the contents of large-scale, heterogeneous data sets is critical to the design of translational clinical studies. In previous reports, we have described the application of a conceptual knowledge engineering technique, known as constructive induction (CI) in order to satisfy such needs. However, one of the major limitations of this method is the need to engage multiple subject matter experts to verify potential hypotheses generated using CI. In this manuscript, we describe an alternative verification technique that leverages published biomedical literature abstracts. Our report will be framed in the context of an ongoing project to generate hypotheses related to the contents of a translational research data repository maintained by the CLL Research Consortium. Such hypotheses will are intended to inform the design of prospective clinical studies that can elucidate the relationships that may exist between biomarkers and patient phenotypes.  (+info)

Discovering synergistic qualities of published authors to enhance translational research. (5/1209)

Translational research is the process of bringing together basic scientific research and improvements in patient care. This process, by its very nature, requires a wide range of skills and resources, typically not found within any single individual. This project investigates the synergistic features of published researchers at the Oregon Clinical and Translational Research Institute(OCTRI) to see how scientists with different specializations can be brought together to improve translational research.The investigated features were author connectivity and complementarity of research subjects. Author connectivity was measured by taking the Average Path Length (APL) and cluster coefficients [1] over an OCTRIcoauthor network. A high degree of connectivity, or low APL value, would indicate that a researcher has participated in many collaborations and published many papers with other OCTRI researchers. This would imply that they have some experience we could leverage to build teams for translational research. Subject complementarity was established by using pairs of frequently co-occurring MeSH terms. Those terms were then used to bridge researchers together through indirect Swanson matching [2] and present evidence of topic synergy, or potential collaborative synergy.Our initial investigation supports the development of a collaborative browsing tool to assist the creation of new translational research teams. Such a tool is being developed at the OCTRI and will include a user-centric evaluation in the near future.  (+info)

Translational research into gut microbiota: new horizons in obesity treatment. (6/1209)

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Lost in translation: what is limiting cardiomyoplasty and can tissue engineering help? (7/1209)

Heart failure accounts for more deaths in the United States than any other detrimental human pathology. Recently, repairing the heart after seemingly irreversible injury leading to heart failure appears to have come within reach. Cellular cardiomyoplasty, transplanting viable cell alternatives into the diseased myocardium, has emerged as a promising possible solution. Translating this approach from the laboratory to the clinic, however, has been met with several challenges, leaving many questions unanswered. This review assesses the state of investigation of several progenitor cell sources, including induced pluripotent stem cells, embryonic stem cells, bone marrow stem cells, adipose-derived adult stem cells, amniotic fluid stem cells, skeletal muscle progenitors, induced pluripotent stem cells and cardiac progenitors. Several current roadblocks to maximum success are discussed. These include understanding the need for cardiomyocyte differentiation, appreciating the role of paracrine factors, and addressing the low engraftment rates using current techniques. Tissue engineering strategies to address these obstacles and to help maximize cellular cardiomyoplasty success are reviewed.  (+info)

Blast-related brain injury: imaging for clinical and research applications: report of the 2008 st. Louis workshop. (8/1209)

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Despite increased emphasis on evidence based practice in recent years a gap remains between evidence and practice, particularly in resource poor countries. Few studies to date have examined the use of knowledge translation strategies to improve health care outcomes in low income countries. However, given that the majority of health care in these settings is provided by workers with less training and limited resources, the theoretical potential for knowledge translation strategies to improve health care delivery and outcomes by integrating best evidence into routine practice may be greatest in these settings.. Knowledge translation (KT) is an approach to changing health care provider behavior to reduce the gap between evidence and practice in health care delivery. There has been a tendency for knowledge translation interventions to employ generic, off the shelf, strategies, and apply them to deal with specific issues. This generic approach, fails to recognize the variability in the specific ...
Despite increased emphasis on evidence based practice in recent years a gap remains between evidence and practice, particularly in resource poor countries. Few studies to date have examined the use of knowledge translation strategies to improve health care outcomes in low income countries. However, given that the majority of health care in these settings is provided by workers with less training and limited resources, the theoretical potential for knowledge translation strategies to improve health care delivery and outcomes by integrating best evidence into routine practice may be greatest in these settings.. Knowledge translation (KT) is an approach to changing health care provider behavior to reduce the gap between evidence and practice in health care delivery. There has been a tendency for knowledge translation interventions to employ generic, off the shelf, strategies, and apply them to deal with specific issues. This generic approach, fails to recognize the variability in the specific ...
An intensive, week-long introduction to translational cancer research - including cancer medicine, the clinical cancer research environment and collaborative team science - for basic scientists who are predoctoral students and postdoctoral fellows, early-career scientists and senior scientists in transition to translational research. This workshop is hosted in close collaboration with the Dana-Farber Cancer Institute/Harvard Cancer Center, comprised of Beth Israel Deaconess Medical Center, Brigham and Womens Hospital, Childrens Hospital Boston, Dana-Farber Cancer Institute, Harvard Medical School, Harvard School of Public Health and Massachusetts General Hospital.. The Translational Cancer Research for Basic Scientists Workshop will provide basic research scientists with a better understanding of translational research, teach them how to adapt their research for maximum clinical impact and help them transition into a new career in translational cancer medicine. This innovative workshop ...
Translational Cancer Research publishes the results of novel research investigations including risk assessment, cellular and prevention, detection, diagnosis and treatment of human cancers.
The Translational Cancer Research for Basic Scientists Workshop will provide basic research scientists with a better understanding of translational research, teach them how to adapt their research for maximum clinical impact, and help them transition into a new career in translational cancer medicine. This innovative workshop addresses many aspects of translational research including leading multidisciplinary teams, working collaboratively and effectively with industry partners, recognizing the unique needs and environment of the clinic and clinical laboratories, dealing with the regulatory and compliance issues in translational science, and understanding the perspective of the patient in order to place research questions into a broader context. During the course of the week, attendees will gain perspective and background knowledge of the disease from translational scientists in academia and industry, clinicians, and patients, while learning about the latest methods and approaches in ...
Clinical and translational medicine plays a unique and critical role in fostering the flow of bidirectional information between basic and clinical scientists, optimizing new biotechnologies, improving clinical application of new therapeutic concepts, and ultimately improving the quality of life for patients. The term Clinical and Translational Medicine (CMT) is defined here as clinical potential and application of translational research and science to improve the understanding of mechanisms and therapies of human diseases, a new and important concept for the development of disease-specific biomarkers and therapeutic strategies to monitor and cure disease. Clinical and Translational Medicine as an international open-access journal publish articles focused on novel advances in clinical, translational, and clinically-relevant basic science, to accelerate the transition from preclinical research to clinical applications and the communication between basic and clinical scientists. Clinical and ...
Although treatment success rates were higher in both intervention arms than in the control and highest in the PALM PLUS and LHW intervention group, the differences did not reach statistical significance. While this may represent a true finding, a number of other factors may be responsible for our failure to detect a significant effect of the intervention.. First, the lack of a significant difference may be an artefact as our projected sample size was not attained due to the loss of four health centers and decreased TB case notification rate during the trial period. The resultant loss of statistical power may have reduced our ability to detect an effect of the intervention. Second, it is possible that the trials pragmatic design contributed to the lack of effectiveness where a more intensively supported program may have been more successful. However, a heavily supported program would not be feasible in the resource-constrained Malawi health care system. Third, it is possible that a significant ...
Centre for Translational Cancer Research news archive, read more news stories about cancer research by our researchers and colleagues at the University of Otago.
Translational Cancer Research (Transl Cancer Res TCR; Print ISSN: 2218-676X; Online ISSN 2219-6803; www.theTCR.org) is an Open Access, peer-reviewed journal, published by Pioneer Bioscience Publishing Company (PBPC), publishes the results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients.
Translational Cancer Research (Transl Cancer Res TCR; Print ISSN: 2218-676X; Online ISSN 2219-6803; www.theTCR.org) is an Open Access, peer-reviewed journal, published by Pioneer Bioscience Publishing Company (PBPC), publishes the results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients.
|p||i|Clinical and Translational Medicine|/i| plays an important and recognized role in reporting knowledge that contributes towards the understanding of molecular mechanisms of disease. |i|Clinical and Translational Medicine|/i| aims to foster a predictive, preventive, personalized and practical approach towards precision medicine, leading to improved patient prognosis. The journal provides a forum for exchange of ideas between basic and clinical scientists on molecular and cellular mechanisms of disease and potential therapies.|/p||p|The journal covers all areas of clinical and translational medicine but also has several special sections:|/p||ul||li|Clinical and translational cardiovascular medicine - Edited by Yong-Xiao Wang|/li||li|Clinical biostatistics - Edited by Christian Baumgartner and Xiangdong Wang|/li||li|Clinical genomics - Edited by Olaf A. Bodamer and Gilbert S. Omenn|/li||li|Stem cell therapies Edited by Mariusz Z. Ratajczak|/li||li|Translational respiratory medicine - Edited by Chunxue
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Basic and Translational Research on Decision Making in Aging and Alzheimers Disease (R01 - Clinical Trial Optional) PAR-18-544. NIA
Biomedical and translational research on sex-drug-gene interactions: what are the trends, gaps, and barriers? Does Canada have the capacity to be a leader in this space ...
Translational Research on the Mechanism of Water and Electrolyte Movements into the Cell Reviewer and Curator: Larry H. Bernstein, MD, FACP Introduction This article is the first in a three part curation covering work that has great importance to our understanding of hydration and possibly the effects of dehydration in cell physiology, and studied effects on…
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Roybal Centers for Translational Research on Aging (P30) RFA-AG-14-004. NIA
Implementation science is the study of methods to promote the adoption and integration of evidence-based practices, interventions and policies into routine health care and public health settings. Implementation research plays an important role in identifying barriers to, and enablers of, effective global health programming and policymaking, and leveraging that knowledge to develop evidence-based innovations in effective delivery approaches.. As outlined in the Centers Strategic Plan, Fogarty aims to support research and research training in implementation science using a distributed approach across its programs. Also, projects coordinated by the Center for Global Health Studies (CGHS) at Fogarty support implementation science research methods and frameworks, and use innovative approaches to supporting implementation science. These projects address a wide variety of critical global health research areas, such as HIV prevention, transmission and treatment; household air pollution; mobile health; ...
This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of compounds interacting with these targets. The rest of book covers the whole downstream pipeline after the identification of lead compounds, such as bioavailability issues, identification of appropriate drug delivery venues, production and scaling issues and preclinical trials. As has been the case with other works in the encyclopedia, the book is made up of long, comprehensive and authoritative chapters, written by outstanding researchers in the field ...
The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) was founded in 2006 to enhance clinical and translational research across the five University of Massachusetts campuses (Amherst, Boston, Dartmouth, Lowell, UMass Medical School) and our clinical partner, UMass Memorial Health Care. With the receipt of an NIH Clinical and Translational Science Award (CTSA) in 2010, and its successful renewal in 2015, the UMCCTS joined a network of 62 NIH-funded centers collaborating to transform the conduct of clinical and translational research across the U.S. The goals of the UMCCTS are to 1) To accelerate the translation of basic discoveries into practical, cost effective solutions that improve human health; and 2) To develop and support the next generation of leaders in clinical and translational research. This collection showcases publications that are the result of UMCCTS supported research.
The Graduate Program in Molecular and Translational Medicine (GPMTM) at Boston University is an interdepartmental, interdisciplinary program based in the Department of Medicine. The mission of the Molecular and Translational Medicine Program is to provide state-of-the-art didactic and research training that produces PhD and MD/PhD scientists who will become leaders in the field of clinically based research.. The program strives to create research opportunities that take full advantage of the wealth of resources available through clinical reagents,clinical expertise, and diverse patient populations at the Boston University Medical Center. At completion of the program each student will have the training and understanding of biomedical systems required to successfully conduct integrative translational research.. ...
FOX CHASE CANCER CENTER has hired Attila Seyhan, PhD, for the newly created position of Director of Translational Medicine Operations. Dr. Seyhan will work closely with Wafik S. El-Deiry, MD, PhD, FACP, Deputy Cancer Center Director for Translational Research, to manage and promote multiple initiatives, including development of investigator-initiated clinical trials and other translational protocols, protocol writing and manuscript preparation, organization of translational medicine events, support for translational requests for application, and grant preparation and submissions. He also will work with industry to follow through on investigator-initiated basic and translational letters of intent and concepts. This work will involve collaboration with clinicians, scientists, regulatory personnel, administrators, tech transfer office staff, the grants management office, institutional review board, institutional advancement, and external entities. A trained molecular biologist, Dr. Seyhan has more ...
The capabilities being gathered into NCATS will offer researchers unparalleled opportunities for intense focus on the reengineering of the translational process, from initial target identification to first-in-human application of small molecules, biologics, diagnostics, and devices. Taking care to avoid a top-down management approach, NCATS will count on the scientific community to conceive highly innovative ideas and propose potential implementation projects. The most promising programs will be funded through NIHs highly respected, peer-reviewed grant- and contract-awarding process. Early discussions with a variety of stakeholders have identified several components of translational science that are ripe for the new scientific approach offered by NCATS and will likely be the subject of early targeted funding opportunities.. Therapeutic target validation. Translational science is awash with newly discovered but unvalidated therapeutic targets. NCATS will support broadly applicable rather than ...
Rotating students interested in the Program in Translational Medicine may find it helpful to know which laboratories on campus have hosted Translational Medicine Trainees in the past. The lists below show the basic science mentors and the clinical co-mentors of all current and past trainees.. ...
High Throughput Sequencing A Pilot Study By Sameek Roychowdhury Matthew K Iyer Dan R Robinson Robert J Lonigro Yi Mi Wu Xuhong Cao Shanker Kalyana Sundaram Lee Sam O Alejandro Balbin Michael J Quist Terrence Barrette Jessica Everett Javed Siddiqui Lakshmi P Kunju Nora Navone John C Araujo Patricia Troncoso Christopher J Logothetis Jeffrey W Innis David C Smith Christopher D Lao Scott Y Kim J Scott Roberts Stephen B Gruber Kenneth J Pienta Moshe Talpaz Arul M Chinnaiyan Science Translational Medicine 30 Nov 2011 111ra121 The mutations present in advanced cancers can be identified by integrative high throughput sequencing to enable biomarker driven clinical trials and ultimately treatment Editor s Summary Abstract Full Text PDF Editors Choice PPAR for the Course in Type 2 Diabetes By Diane Gesty Palmer Science Translational Medicine 30 Nov 2011 111ec192 Targeting adipocyte specific PPARγ may be a new strategy for treating type 2 diabetes Full Text Genetic Screening to Beat Cancer By Carrie M ...
In order to accomplish these objectives open discussion and cooperation among companies, academic, and other institutions will be increasingly important. For all of these reasons, we have created a new subsection of the Journal of Translational Medicine.. Why should a Subsection of the Journal of Translational Medicine be dedicated to combination strategies? Because we want to stimulate discussion over this hot topic. In recent years, several compounds have been developed to treat a broad number of diseases targeting a specific mechanism. However, vast majority of common diseases are multi-factorial and cannot realistically be controlled by targeting a single or few pathways.. Tuberculosis treatment is a classic example of combination therapy [1]. After the discovery of Streptomycin in 1944, improvement in the effectiveness of therapy was observed with the addition of Isoniazid, the first oral mycobactericidal drug in 1952 and Rifamycins in 1957. The introduction of Rifampicin in 1970 further ...
Summary of Translational Medicine - e-Series A: Cardiovascular Diseases, Volume Four - Part 1 Author and Curator: Larry H Bernstein, MD, FCAP and Curator: Aviva Lev-Ari, PhD, RN Part 1 of Volume 4 in the e-series A: Cardiovascular Diseases and Translational Medicine, provides a foundation for grasping a rapidly developing surging scientific endeavor that…
Translational Medicine Communications is an interdisciplinary forum for all scientifically valid research from across translational medicine. We are committed ...
Annals of Translational Medicine&Epidemiology is an open access journal committed to publish articles in all areas of Translational Medicine&Epidemiology.
Fishpond Australia, Carotenoids and Vitamin A in Translational Medicine (Oxidative Stress and Disease) by Werner Siems (Edited ) Olaf Sommerburg (Edited ). Buy Books online: Carotenoids and Vitamin A in Translational Medicine (Oxidative Stress and Disease), 2013, ISBN 1439855269, Werner Siems (Edited by) Olaf Sommerburg (Edited by)
Mayo Clinic Center for Clinical and Translational Science (CCaTS):Graduates of the Ph.D. track in clinical and translational science.
We support translational studies and cross-disciplinary investigation in epidemiology, behavioral health, clinical trials, and public health. The Core will expand its longitudinal database from the existing clinical cohorts to include neuropsychiatric and neurocognitive assessment of a large well-characterized urban minority patient population. The core assists in the development, design, and performance of studies that transition basic research to the bedside and at the same time foster the transition of clinical observations and hypotheses to the laboratory. This Core further interacts with the International HIV Medicine and Research Core to provide training in advanced HIV care and neurocognitive assessment that can be used at the international site to both improve the quality of patient care and also to perform meaningful neurocognitive assessment that benefits patients as well as the research community.. ...
Access a targeted collection of scientific application notes, case studies, videos, webinars, and white papers for clinical and translational research.
The aim of this research topic is to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life. CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial, but commonly involves hypoxia in premature babies, or perinatal strokes. Corticospinal axons have just invaded the spinal grey matter and thalamic afferents the upper layers of the neocortex, and these systems are undergoing activity dependent development. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry including heteronymous and hyperexcitable reflexes, and uprated ipsilateral corticospinal inputs that are not functionally useful. CP may be viewed
NIMH held this multidisciplinary workshop to identify major trends, gaps, and opportunities in clinical and basic research on repetitive behavior and resistance to change in autism.
Imaging genomics has increasingly moved towards a GWAS approach, using large-scale collaborations to improve power for the detection of variants with small independent effects [29]. Examples of such consortia include the Enhancing Neuro-imaging through Meta-analysis (ENIGMA) consortium [37], Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium [36], Alzheimers Disease Neuroimaging Initiative (ADNI), IMAGEN, which is focused on adolescents [38], and the Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement (UNIVRSE) consortium [39]. The growing number of GWAS of brain phenotypes and of neuropsychiatric disorders has, on occasion, lent support to previously reported candidate variants [40], but importantly has identified many new variants of interest [41].. An early study by the ENIGMA consortium consisted of approximately 8000 participants, including healthy controls and cases with psychiatric disorders [42]. This study identified significant associations between ...
Cerebral palsy (CP) is defined as a group of permanent disorders of the development of movement and posture, causing activity limitation, attributed to non-progressive disturbances occurring in the developing fetal or infant brain(1). Lesions to the sensorimotor cortex, subcortical axon tracts and subplate are often implicated, with other motor and non-motor areas frequently also affected. The aetiology is complex and often multifactorial (2); causes include hypoxia(3), stroke(4) , infection(5), trauma and genetic factors(6). By the end of the second trimester, corticospinal axons have invaded the spinal grey matter and thalamic afferents the upper layers of the neocortex (7, 8). These systems undergo activity-dependent development (9, 10). After early brain injury, descending pathways are disrupted, with abnormal development of reflex and corticospinal circuitry (11, 12). Movement abnormalities are initially subtle but develop subsequently (13, 14). Aberrant post-lesional plasticity undoubtedly
Preterm labour continues to be a major contributor to neonatal and infant morbidity. Recent data from the USA indicate that the number of preterm deliveries (including those associated with preterm labour) has risen in the last 20 years by 30%. This increase is despite considerable efforts to introduce new therapies for the prevention and treatment of preterm labour and highlights the need to assess research in this area from a fresh perspective. In this paper we discuss i) the limitations of our knowledge concerning prediction, prevention and treatment of preterm labour and ii) future multidisciplinary strategies for improving our approach.
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder with monogenic mutations setting the stage for successful gene therapy treatment. We have completed a study that directly deals with the following key issues that can be directly adapted to a gene therapy clinical trial using rAAV considering the following criteria: 1) A regional vascular delivery approach that will protect the patient from widespread dissemination of virus; 2) an approach to potentially facilitate safe passage of the virus for efficient skeletal muscle transduction; 3) the use of viral doses to accommodate current limitations imposed by vector production methods; 4) and at the same time, achieve a clinically meaningful outcome by transducing multiple muscles in the lower limb to prolong ambulation. The capacity of AAV1, AAV6 or AAV8 to cross the vascular endothelial barrier carrying a micro-dystrophin cDNA was compared under identical conditions with delivery through a catheter placed in the femoral artery of the mdx
Objectives: Toll like receptor (TLR) signaling emerged as a significant pathway in our whole genome peripheral blood study of ischemic stroke patients. In our dataset, TLR signaling is associated with stroke severity, can predict outcome and is influenced by age. The age-mediated effects on TLR expression and kinase signaling in response to cerebral ischemia are not well-characterized. The objective of this project was to confirm and further characterize our clinical findings in a preclinical aged stroke model by analyzing TLR gene expression and the kinase proteome.. Methods: An SaBiosciences rat TLR PCR array was used to compare brain and blood gene expression in 3 (n=3) and 18 (n=3) month old rats that underwent embolic middle cerebral artery occlusion (MCAO) with tPA reperfusion and sacrificed at 24 hours. Blood samples were collected via femoral artery in Qiagen RNA protect tubes. Rats were perfused and then Brain tissue was collected in RNA later. A Kinetworks Protein Kinase Screen 1.2 was ...
Research funding agencies, industry and academic institutions have placed increased attention to the issue of ensuring research methods and results are reproducible. Irreproducible data poses a danger to the fundamental mission and promise of translational science, and data reproducibility should be considered as integral to the translational research process. This session will present approaches, tools and best practices to integrate data reproducibility and rigor into translational research programs. Additionally, key federal policies and initiatives impacting data quality and rigor will be discussed ...
The Institute for Translational Medicine and Therapeutics (ITMAT) supports research at the interface of basic and clinical research focusing on developing new and safer therapeutics. ITMAT includes faculty, basic research space, and the Clinical and Translational Research Center (CTRC), which derives from the integration of the former General Clinical Research Center (GCRC) of both Penn and the Childrens Hospital of Philadelphia (CHOP). ITMAT also offers research cores, educational programs (including a Masters in Translational Research), and research programs and centers. These are designed to facilitate training and research from proof of concept in cellular and animal model systems across the translational divide to proof of concept and dose selection in humans.
The Institute for Translational Medicine and Therapeutics (ITMAT) supports research at the interface of basic and clinical research focusing on developing new and safer therapeutics. ITMAT includes faculty, basic research space, and the Clinical and Translational Research Center (CTRC), which derives from the integration of the former General Clinical Research Center (GCRC) of both Penn and the Childrens Hospital of Philadelphia (CHOP). ITMAT also offers research cores, educational programs (including a Masters in Translational Research), and research programs and centers. These are designed to facilitate training and research from proof of concept in cellular and animal model systems across the translational divide to proof of concept and dose selection in humans.
Accelerating Research to Improve Health. The UCSF Clinical and Translational Science Institute (CTSI) is part of the Clinical and Translational Science Award (CTSA) program funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) (Grant Number UL1 TR991872). The content of this website is solely the responsibility of CTSI and does not necessarily represent the official views of the NIH.. Cite CTSI NIH Funding Acknowledgment: Important - All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH Funding acknowledgment and must comply with NIH Public Access Policy.. ...
This Clinical and Translational Science Awards (CTSA) Consortium website is funded by the U.S. National Institutes of Health, grant 1U54RR032646-01 ...
Malignant mesothelioma is a cancer refractory to current therapies. Imatinib Mesylate (STI571, GlivecTM) is a selective inhibitor of tyrosine kinases as bcr-abl, c-Kit, c-Fms and Platelet Derived Growth Factor Receptorβ (PDGFRβ). PDGFRβ is often overexpressed in mesothelioma cells and is a therapeutic target for Imatinib in some solid tumors. The aim of this study is to assess whether Imatinib alone or combined with chemotherapeutic agents may be successful for mesothelioma therapy. Cultures from mesothelioma MMP, REN and ISTMES2 cell lines, were treated with Imatinib alone or in combination with chemotherapeutic. We show here that Imatinib induces cytotoxicity and apoptosis selectively on PDGFRβ positive mesothelioma cells, via blockade of receptor phosphorylation and interference with the Akt pathway. Among chemotherapeutics tested in combination, Imatinib synergizes with Gemcitabine and Pemetrexed. We provide a rationale for a novel translational approach to mesothelioma therapy, relying ...
Exciting opportunity in Nashville, TN for Vanderbilt Health as a Clinical Translational Research Coordinator II - Cognitive/Behavioral Neurology
Rockefeller Universitys Center for Clinical and Translational Science, established a decade ago to accelerate the pace of translating scientific discoveries into interventions shown to improve health, has received $27 million from the National Institutes of Health to fund ongoing and expanded work over the next five years. The Clinical and Translational Science Award (CTSA), which has funded the center since its inception, is designed to improve the translational research process and foster innovation in research methods, training, and career development.. The award maintains CTSA funding that began in 2006, when Rockefeller was selected as one of the first 12 institutions to receive it, and then continued through the universitys successful renewal in 2011. With this award, which is technically not a renewal, Rockefeller has received more than $115 million in CTSA funding.. Im delighted that we will continue to be funded through the CTSA, says Center for Clinical and Translational Science ...
http://sig3perspectives.pubs.asha.org/article.aspx?articleid=1777062 From Bench to Bedside: Translational Research on Vocal Fold Hydration The importance of well-hydrated vocal folds in maintaining optimal voice function is widely acknowledged. In this article, we summarize findings from recent bench and bedside research and highlight how use of these experimental techniques has improved our understanding of the physiological mechanisms that regulate vocal fold hydration. ... 2008-11-01T00:00:00 Article Mahalakshmi Sivasankar ...
W Michael Foster Jiurong Liang Eric B Meltzer Dianhua Jiang Robert J Lefkowitz Paul W Noble Science Translational Medicine 16 Mar 2011 74ra23 The signaling molecule β arrestin is required for the fibroblast invasion of extracellular matrix and thus for the development of pulmonary fibrosis Editor s Summary Abstract Full Text PDF The Δ F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis Like Disease in Pigs By Lynda S Ostedgaard David K Meyerholz Jeng Haur Chen Alejandro A Pezzulo Philip H Karp Tatiana Rokhlina Sarah E Ernst Robert A Hanfland Leah R Reznikov Paula S Ludwig Mark P Rogan Greg J Davis Cassie L Dohrn Christine Wohlford Lenane Peter J Taft Michael V Rector Emma Hornick Boulos S Nassar Melissa Samuel Yuping Zhang Sandra S Richter Aliye Uc Joel Shilyansky Randall S Prather Paul B McCray Jr Joseph Zabner Michael J Welsh David A Stoltz Science Translational Medicine 16 Mar 2011 74ra24 A common mutation in human cystic fibrosis CFTR ΔF508 results in misprocessed CFTR and a ...
The universitys new Clinical and Translational Science Institute plans to add clinician-scientists and cooperate with other core research centers with the aim of becoming a member of NIHs Clinical and Translational Science Awards consortium.
The vaginal distention (VD) translational model for postpartum stress urinary incontinence (SUI) is potentially biased for use in evaluating animals with increasing phenotypic size (obesity) due to a fixed VD volume. Our study had three principle and two secondary aims. First, to examine both ex vivo and in vivo catheter pressure changes during volume distention. Secondly, to determine mean pressure at current volume standard for use as target pressure (TP) for VD under isobaric (IB) conditions. Thirdly, to demonstrate feasibility and equivalence of VD at TP versus isovolumetric (IV) standard. Secondary aims were to demonstrate decreased variability (IB vs. IV) and to review the effect of weight. ...
The Clinical Research Education and Career Development Program (CRECD) at MSM is pleased to announce that a record number of six scholars were sponsored to attend and present their research at the Association of Clinical Research Training/Society of Clinical and Translational Science (ACRT/SCTS) Joint Annual Scientific Sessions this week in Washington DC. Two scholars, Djana Harp, MD, MS and Baraka Floyd (MD and MS candidate) were research award winners and Lilly Immergluck, MD was a travel award winner. According to Alexander Quarshie, MD, who participated as a poster judge, this was a very competitive process and award winners had to be judged as excellent by three independent judges. Congratulations to these scholars and their mentors, and to the research award winners:. ...
The Community-Based Clinical Research Centers are supported by the William T. Dahms, MD Clinical Research Unit (DCRU) and utilize the research network of the Cleveland Clinical & Translational Science Collaborative of Cleveland (CTSC), UL1TR000439, from the National Center of Advancing Translational Sciences (NCATS) component of the National Institutes of Health, to expand clinical/translational research resources available to both academic and community-based research programs. The Dahms Clinical Research Unit is a joint effort with the Case Western Reserve University School of Medicine ...
Supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under Award number UL1TR002378. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. KL2 Scholars should also list KL2TR002381 and TL1 Trainees should also list TL1TR002382 ...
Dr. Cellucci is an Associate Professor in the Department of Pediatrics, Division of Rheumatology. She completed her medical degree and subsequent fellowships in Rheumatology at the University of Toronto and The Hospital for Sick Children, and pursued her postgraduate training in pediatrics at Western University. While completing her research fellowship at Sick Kids, she worked as a locum physician in pediatric rheumatology at Albertas Childrens Hospital in Calgary.. As an investigator, Dr. Celluccis interests are in the field of childhood inflammatory brain diseases. Her most recent study focuses on developing a knowledge translation intervention to build physician knowledge about childhood CVS vasculitis, and promote practice change.. In addition to her research, she is currently completing a Masters of Science in Community Health in the Health Practitioner Teacher Education Program at the University of Toronto, with a focus on knowledge translation for rare diseases. Recently, she led a key ...
The CTRC provides infrastructure, resources, and dedicated space to conduct clinical research. Available resources include a staff physician, research nursing, exercise physiologist, bionutritionist, pharmacy services, statistics, and adverse event management. Our services are provided on a fee for service basis. You can find a price list of our most common procedures below. Some procedures are subject to change based on protocol specifics. Please contact the CTRC Administrator for more information.. In compliance with University policy we conduct a price assessment every fiscal year, our current prices are valid until June 30th. When budgeting for a new project it is recommended that you add 6% to account for any inflation that may occur.. ...
Other authors of the paper (Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling) were lead author and postdoctoral fellow Kyle Timmerman, medical student Jessica Lee, assistant professor Hans Dreyer, research scientist Shaheen Dhanani, graduate students Erin Glynn and Christopher Fry, assistant professor Micah Drummond, associate professor Melinda Sheffield Moore, and professor Blake Rasmussen. Specialized metabolic studies were conducted by the staff of the UTMB Clinical Research Center, part of the universitys Institute for Translational Sciences. The National Institute on Aging, the UTMB Claude D. Pepper Center Older Americans Independence Center, the National Institute of Child Health and Human Development and the UTMB Clinical Translational Sciences Award supported this study. ...
Although the CTSA program is young, there have already been examples that show how partnering with CTSA researchers can benefit pharmaceutical companies. One is the Yale Clinical trial network, which should streamline and improve the clinical trials process for the companies that are part of it. Among other goals, the network will remove barriers to clinical trials and promote trial participation. There is also at least one example of a cross licensing agreement between a CTSA funded researcher and industry. Dr. Daniel Rader, at the University of Pennsylvania, took advantage of his universitys CTSA to develop an MTP inhibitor that was very effective in treating a rare disease called familial hypercholesterolemia. Seeing the potential of lower doses of the drug to treat patients at risk of heart disease, Aegerion Pharmaceuticals is developing the drug for this purpose.. ...
Supported by US National Institutes of Health Clinical Translational Science Award 1 KL2 RR024151-01 (Mayo Clinic Center for Clinical and Translational Research), and the resources and facilities at the Birmingham VA Medical Center, Alabama, USA. The original study was supported by unrestricted grants to scientific societies (Osteoarthritis Research Society International and Outcome Measures in Rheumatology) from pharmaceutical companies: Pfizer, Expansciences, Novartis, Negma Lerads, Rottapharm, Fidia, and Pierre Fabre Santé laboratories, and a research grant from the European League Against Rheumatism. Dr. Suarez-Almazor is the recipient of a K24 award from the National Institute for Arthritis, Musculoskeletal, and Skin Disorders (AR053593). Dr. Singh has received research and travel grants from Takeda and Savient, and consultant fees from Savient, Regeneron, Takeda, and Allergan. ...
Professor Jacob George and his team are committed to reducing the burden of liver cancer on NSW. He says there is still a long way to go, but there are promising signs.. Modelling from the Kirby institute demonstrates that in NSW, since the introduction of the new hepatitis C treatments, the increasing burden of liver cancer has plateaued.. Projections show liver cancer incidence state-wide will decline over the next few years with increasing treatment coverage, Professor George explains.. To help achieve this goal, Western Sydney Local Health District has officially launched a mobile van to make hepatitis C testing much easier and faster.. The van is offering free blood collection and blood spot testing for hepatitis C by specialist staff, along with HIV testing.. The van will be in Paramatta for two furter dates in June and August, and Castle Hill in September. See the Liver Wellness Program for more information.. ...
Current list of Benefactor-Funded Research Career Development Awards available through Mayo Clinics Center for Clinical and Translational Science (CCaTS).
The Translational Science of Rare Diseases - From Rare to Care III , Endo-ERN, The Translational Science of Rare Diseases - From Rare to Care III symposium, hosted by the BMBF-funded German Research for Rare network, will take place from April 11 to 13,
Despite phenomenal progress in basic science, we still lack effective treatments for far too many diseases, and this translational pipeline to get there is long, 14 years on the average, and its leaky, said NIH Director Dr. Francis Collins during congressional testimony on March 20. Both Collins and NCATS Acting Director Dr. Thomas Insel testified on the Presidents FY 2013 budget request before the U.S. House of Representatives Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies, chaired by Rep. Denny Rehberg (R-MT).. The hearing focused on both the NIH and NCATS budgets and featured panel discussions about the many opportunities that exist for NCATS to work in synergy with private industry to improve the translation process. Collins also restated NIHs commitment to fund basic biomedical research as its highest priority. Insel showcased NIHs Clinical and Translational Science Awards program, saying 80 percent of [the NCATS] budget is the CTSA ...
Columbia University Medical Centers (CUMC) CTSA and Irving Institute for Clinical and Translational Research (IICTR), using the expertise and commitment of fac...
Rajita Sinha, Ph.D. is the Foundations Fund Professor in the Department of Psychiatry at Yale University and also Professor of Neurobiology and Child Study. She is Chief of the Psychology section in Psychiatry and Co-Director of Education at the Yale Center for Clinical Investigation (the Yale Clinical Translational Science Award). She is the Founding Director of the Yale Stress Center, a university-wide center that focuses on understanding the effects of stress on emotions, mood and behavior, in order to improve health outcomes relating to choices and maladaptive behaviors. She is internationally known for her pioneering research on the mechanisms linking stress, emotions to addictive behaviors and health outcomes. Her research is making discoveries on the link between stress, mechanisms like glucocorticoids, immune adaptations and effects on brain structure, function and its impact on bheaviors, decisions and chronic disease risk. She is also developing and testing new pharmacological and ...
The Community-Based Clinical Research Centers are supported by the William T. Dahms, MD Clinical Research Unit (DCRU) and utilize the research network of the Cleveland Clinical & Translational Science Collaborative of Cleveland (CTSC), UL1TR000439, from the National Center of Advancing Translational Sciences (NCATS) component of the National Institutes of Health, to expand clinical/translational research resources available to both academic and community-based research programs. The Dahms Clinical Research Unit is a joint effort with the Case Western Reserve University School of Medicine ...
The Department of Biostatistics is responsible for the development and delivery of the postgraduate statistics teaching programme for PhD students in the Faculty of Health and Life Sciences, a new research strand, Biostatistics and Bioinformatics, in the MRes in Biomedical Sciences and Translational Medicine Master Course, a new MSc in Clinical Research Administration in partnership with Laureate Online Education (http://www.liv.ac.uk/study/online/index) and a number of CPD courses that are designed to provide healthcare professionals with basic statistical research skills.. ...
TY - JOUR. T1 - Adding Social Determinant Data Changes Childrens Hospitals Readmissions Performance. AU - Sills, Marion R.. AU - Hall, Matthew. AU - Cutler, Gretchen J.. AU - Colvin, Jeffrey D.. AU - Gottlieb, Laura M.. AU - Macy, Michelle L.. AU - Bettenhausen, Jessica L.. AU - Morse, Rustin B.. AU - Fieldston, Evan S.. AU - Raphael, Jean L.. AU - Auger, Katherine A.. AU - Shah, Samir S.. N1 - Funding Information: M.S. supported by the National Heart, Lung, and Blood Institute (5R21HL123589-02), the Health Resources and Services Administration, Maternal Child Health Research Program (R40-111810) and the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program (UL1 TR001082). G.C. supported by Childrens Hospitals and Clinics of Minnesota, the Medica Research Institute and National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program (UL1TR000114). E.F. Funded by the Agency for Healthcare Research and Quality (1R01HS023538-A1). ...
TY - JOUR. T1 - Defining disease, diagnosis, and translational medicine within a homeostatic perturbation paradigm. T2 - The National Institutes of Health undiagnosed diseases program experience. AU - Gall, Timothy. AU - Valkanas, Elise. AU - Bello, Christofer. AU - Markello, Thomas. AU - Adams, Christopher. AU - Bone, William P.. AU - Brandt, Alexander J.. AU - Brazill, Jennifer M.. AU - Carmichael, Lynn. AU - Davids, Mariska. AU - Davis, Joie. AU - Diaz-Perez, Zoraida. AU - Draper, David. AU - Elson, Jeremy. AU - Flynn, Elise D.. AU - Godfrey, Rena. AU - Groden, Catherine. AU - Hsieh, Cheng Kang. AU - Fischer, Roxanne. AU - Golas, Gretchen A.. AU - Guzman, Jessica. AU - Huang, Yan. AU - Kane, Megan S.. AU - Lee, Elizabeth. AU - Li, Chong. AU - Links, Amanda E.. AU - Maduro, Valerie. AU - Malicdan, May Christine V.. AU - Malik, Fayeza S.. AU - Nehrebecky, Michele. AU - Park, Joun. AU - Pemberton, Paul. AU - Schaffer, Katherine. AU - Simeonov, Dimitre. AU - Sincan, Murat. AU - Smedley, ...
BioSiteHistos services were acknowledged and made the front cover of the March Issue of Stem Cells Translational Medicine. Of special note is that two of our reliable Optibodies™ were used for the histology part of the study.. Improved quality of life is a major goal for treatment of pelvic floor disorders such as anal incontinence that can be a result of sphincter injury. In the study it was observed that the functional measurements showed improvement in treated groups as compared with controls. In the original article, from authors at Tampere University Hospital, University of Tampere and Tampere University of Technology the functional outcomes of human adipose stem cell (hASC) injections in a rat model were studied. It was also found that Bulkamid is a suitable carrier for stem cells and that a novel method of micro-computed tomography was useful for targeting the histological slides.. The article is available as open access and you can read the full article here. References ...
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We are seeking a highly motivated and enthusiastic associate to join our pre-sampling team in the Translational Medicine group. The position will involve direct handling and processing of highly valuable clinical specimens from our external collaborators as well as tracking work in a laboratory inventory management system (LIMS). This contractor will also be required to store samples appropriately, potentially assist with nucleic acid extractions, and assist in a variety of other lab organizational tasks to ensure efficient and organized processing of patient samples ...
The UR CTSI is dedicated to engaging the community at all stages of research. Community engagement helps health research address community needs and is a philosophy that supports partnership between community and academics to develop strategies that address those needs. At the UR CTSI, we train researchers and community members to work together and provide funding to support and advance these partnerships.. ...
The Knowledge Translation for Employment Research Center (KTER) develops and tests knowledge translation strategies designed to help vocational rehabilitation agencies and businesses find, understand, and use research related to employing people with disabilities.
Introduction TRECARD promises to respect any personal data you share with us, or that we get from other organisations and keep it safe. We aim to be clear when we collect your data and not do anything you wouldnt reasonably expect. Developing a better understanding of our supporters through their personal data allows us…
TY - JOUR. T1 - Patient and physician views of shared decision making in cancer. AU - Tamirisa, Nina P.. AU - Goodwin, James S.. AU - Kandalam, Arti. AU - Linder, Suzanne K.. AU - Weller, Susan. AU - Turrubiate, Stella. AU - Silva, Colleen. AU - Riall, Taylor S.. N1 - Funding Information: Funding information Cancer Prevention Research Institute of Texas Grant # RP140020, UTMB Clinical and Translational Science Award # UL1TR000071, NIH T-32 Grant # T32DK007639, AHRQ Grant # 1R24HS022134, and NIH Grant # K05-CA 134923 This study is dedicated to the memory of Suzanne Kneuper Linder, Ph.D. (8 January 1977-9 October 2014). She was a major contributor to this study. Her passion for qualitative research and dedication to improving physician?patient communication served as an example to all who worked with her. Funding Information: Cancer Prevention Research Institute of Texas Grant # RP140020, UTMB Clinical and Translational Science Award # UL1TR000071, NIH T-32 Grant # T32DK007639, AHRQ Grant # ...
The NIH Broadening Experiences in Scientific Training (BEST) program is designed to develop innovative approaches to prepare students and postdocs for a range of careers. As part of the University of Rochester (UR BEST) Science and Technology Policy Pathway, trainees interested in the Regulatory Science and Personalized Medicine Track will learn key competencies in Regulatory Science and Personalized Medicine through internships and experiential opportunities that prepare them for careers at the FDA, NIH, Centers for Disease Control and Prevention (CDC), pharmaceutical and medical device industry, academic institutions and a range of other government agencies and NGOs. Participants interested in the management and oversight of science can explore opportunities in the Regulatory Affairs Compliance and Review Pathway.. ...
Translational Research in Medical Imaging. Second International Workshop, CLIP 2013, Held in Conjunction with MICCAI 2013, ... computer vision health informatics image classification image processing image segmentation interventional planning medical ...
Previous CME Translational Pain Research Forum Speakers and Topics. May 25, 2011 ... Paul Dougherty, D.C.: Chiropractic Research: Ongoing Federally Funded Chiropractic Research in the Rochester Area ... Harvard Medical School); Donna Thomas, M.D. (SUNY Upstate); Robert Dworkin, Ph.D. (URMC); Babak Jahromi, M.D. (URMC); Melanie ...
5th Anniversary Celebration of the Translational Research Unit. November 7, 2018 , 1:00 pm-3:00 pm iCAL ... Research * Basic Science Research Our scientists are discovery-drivers, working to develop cutting-edge treatments. ... Medical School Choose from a three or four-year MD program at various campus locations, our anesthesiologist assistant or a ... Pancreatic Cancer Translational Science Symposium. A Return to the ABCs October 25, 2019 , 9:00 am-5:00 pm ...
THS Plenary Research Seminars. Translational Health Sciences runs a programme of research talks each year from a blend of up- ... Translational Health Sciences staff can contact Moth Broyles to arrange transport to the venue. (Tel: 0117 33 11831 or e-mail: ... We hope the seminars will be informative and inspirational to all staff and students in Translational Health Sciences, and also ... Members of the public welcome - e-mail ths-research@bristol.ac.uk for information about venues and access. ...
Dementia Research Group. The Dementia Research Group conducts laboratory-based (preclinical) research that translates into ... Our laboratory-based research is almost exclusively undertaken in the Learning & Research building, at Southmead Hospital, ... Dementia Research Group. University of Bristol. Level 1, Learning & Research. Southmead Hospital. Bristol, BS10 5NB ... It is also a member of the Bristol and Bath Alzheimers Research UK Network Centre, one of the main partners in the Brains for ...
The Translational Pain Research Program conducts leading edge clinical research across the spectrum of acute, peri-operative, ... The program draws on the resources of the university to conduct investigator- initiated research designed to address key ...
The most promising areas of translational medical research, including CAR-T cancer therapies and stem cell-based regenerative ... Quad introduces MagCloudz Streptavidin Cell Separation Kit to redefine translational medical research. *Download PDF Copy ... The most promising areas of translational medical research, including CAR-T cancer therapies and stem cell-based regenerative ... Medical Research, Medicine, Research, Stem Cells, T-Cell, Tumor ... News-Medical.Net provides this medical information service in ...
T1 TO T3 MEDICAL EDUCATION RESEARCH. Medical education research at the T1 level-the most common form of such research-involves ... Medical Education Research As Translational Science Message Subject. (Your Name) has forwarded a page to you from Science ... Medical education research is T1 translational science when its results show trainee skill and knowledge improvement in ... Research on medical education is translational science when rigorous studies on trainee clinical skill and knowledge ...
The Medical Center for Translational and Clinical Research supports the clinical application of these new treatment methods at ... the research stage, and also promotes the development of new therapies. Currently, we are conducting studies on ...
Based at the UCD Clinical Research Centre. Course Overview. The MSc in Clinical and Translational Research aims to train the ... Develops core research competencies and clinical and translational research principles. *Instructs students in the principles ... Director, UCD Clinical Research Centre. UCD School of Medicine & Medical Science. Catherine McAuley Education & Research Centre ... which you can use to develop your own research activities. To complete the UCD MSc in Clinical & Translational Research you ...
... - Apr 28, 2006 - ... Erasmus University Medical Center Uses SGI Technology for Groundbreaking Translational Medicine Research Silicon Graphics ... Translational Medicine. The research application of I-space with the Silicon Graphics system deals with genomics data mining ... I-space at Erasmus Medical Center. At Erasmus MC, I-space is used for two reasons: research and clinical diagnostics. The ...
... physician-scientists at UH Cleveland Medical Center are advancing medical care through education and innovative research that ... Research and Development. Overview. At University Hospitals Translational Laboratory we aim for the development of assays based ... University Hospitals Cleveland Medical Center is the flagship academic medical center at the core of UHs 18 hospital health ... Through faculty appointments at Case Western Reserve University School of Medicine and through research conducted with support ...
Research Fellowship is one of several long and short term oncology fellowships from the European Society for Medical Oncology ... Global Curriculum in Medical Oncology *Curriculum in Translational Research in Breast Cancer ... Medical Oncologist, General Public Hospital Spittal/Drau, Austria *Clinical Research Fellow, Sarah Cannon Research Institute, ... Recognition and Status of Medical Oncology. Medical oncology is included among the medical specialities covered by the European ...
... in medical imaging. The report, published in the May 28, 2019, Journal of the American College of Radiology. ... with contributions from NIBIB provides a roadmap for translational research on artificial intelligence (AI) ... NIH and radiology societies map path for translational research on AI in medical imaging Share:. ... NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is ...
At Lahey Hospital & Medical Center, medical advances continue to develop, thanks to the enterprising efforts of our clinicians ... Continuing medical research is the key to the future of patient care. ... https://www.lahey.org/lhmc/research-residencies/research/translational-research/. *https://www.lahey.org/lhmc/research- ... At Lahey Hospital & Medical Center, scientists and physicians collaborate on translational research paving the way for future ...
Research Research. Garvans medical research will transform healthcare. We explore the full spectrum of disease so that ... Disease-focused research activities. The Translational Genomics Informatics Team conducts research in the following disease- ... Translational Bone group, Andreas Zankl. Genomic determinants of bone mineral density. Osteoporosis & Translational Research ... The Garvan Institute of Medical Research (ABN 62 330 391 937) and the Garvan Research Foundation (ABN 91 042 722 738) are ...
Read on to understand how the Department of Surgery at OSU uses translational research. ... Translational research is important to understand and treat medical challenges. ... Basic and Translational Research. Building the bridge from development to treatment. Translational research is a key component ... Highlights in translational research. Regenerative medicine for vital organ injury. The focus of Dr. Jianjie Mas research ...
Our research is focused on the epidemiology of osteoporosis, defining optimal treatment pathways and identifying novel genetic ... Research Research. Garvans medical research will transform healthcare. We explore the full spectrum of disease so that ... The Garvan Institute of Medical Research (ABN 62 330 391 937) and the Garvan Research Foundation (ABN 91 042 722 738) are ... Osteoporosis and Translational Research Lab https://www.garvan.org.au/research/healthy-ageing/osteoporosis-and-translational- ...
Advances in machine learning in medical imaging are occurring at a rapid pace in research laboratories both at academic ... A Road Map for Translational Research on Artificial Intelligence in Medical Imaging: From the 2018 National Institutes of ... Advances in machine learning in medical imaging are occurring at a rapid pace in research laboratories both at academic ... publications that identify and prioritize initiatives to accelerate foundational and translational research in AI for medical ...
Translational Research Unit, 575863106 in Los Angeles, CA. View job details and apply for the job. ... Los Angeles Medical Centers has a job for RN-Clinical & ... RN-Clinical & Translational Research Unit UCLA Title: Clin ... RN-Clinical & Translational Research Unit This job is no longer active. View similar jobs.. POST DATE 8/12/2016 END DATE 1/27/ ... To provide patient care for research subject in the CTRC, required to follow all UC, State and GCP policies as applied to the ...
... bietet Stelle als Head of Division Translational Medical Oncology / Advanced Clinician Scientist (m/f/d) in ... The German Cancer Re-search Center is the largest bio-medi-cal re-search insti-tu-tion in Germany. With approx-imate-ly 3,000 ... Head of Division "Translational Medical Oncology". (Advanced Clinician Scientist; DKFZ-University Medical Center Mannheim). ( ... Head of Division Translational Medical Oncology / Advanced Clinician Scientist (m/f/d) Veröffentlicht am 22.03.2019 ...
... is responsible for ensuring strong continued support for translational research across the MRC. ... Translational Research Group. The Translational Research Group (TRG) is responsible for ensuring strong continued support for ... translational research across the MRC. We support translational research across our funding Boards and Panels, through ... UK Dementia Research Institute (DRI) - Call for DRI Centre proposals * UK Dementia Research Institute: Selecting a world- ...
Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and ... A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she has successfully ... A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she has successfully ... The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses ...
Oncology with University of Michigan Medical Center. Apply Today. ... University of Michigan Medical Center Location Ann Arbor, ... Sarcoma Translational Research Oncology Faculty Position in Permanent, Hematology / ... Successful candidates will have a strong background in translational research, particularly in lab-based research focused on ... A generous start up package and protected time will be provided to pursue research interests and develop a clinical research ...
Research and development of Next Generation Endoscopic Intervention extra medical equipment based on industry-academia ... Research and Development Department. Common Fundamental Technology Department. Research Support Department Projects. ... Research and development of novel drug screening and stem cell culture systems for heart disease treatments. ... Research and development to increase the availability of treatments for critical limb ischemia through regenerative medicine ...
... NACIF, Lucas Souto ; KIM, Vera ; GALVAO, Flavio ; ... All the selected studies on the management of translational medical research in liver transplantation (LT) were analyzed. ... In conclusions, this review demonstrates the application of scientific research with translation medical benefits regarding the ... Translational medicine has become a priority, but there is still a big difference between the arrival of new treatments and ...
The Translational Research Grants Scheme funds NSW Health employees to build research capability and accelerate evidence ... The research directory lists all TRGS and other research projects and devices that Office for Health and Medical Research have ... descriptive research (i.e. research that is idea generation or monitoring as described in the Translational Research ... Office for Health and Medical Research, NSW Ministry of Health , Translational Health Research Institute, Western Sydney ...
Translational trials. PStudies that test whether basic science advances are applicable to patient care ... Clinical research Confused by clinical research methods? Get a clue!. 03.08.2017 An interactive learning tool that will turn ... Readers of medical journals are not spared. Articles are full of jargon, and its not medical Latin like in the old days. ... Swiss Medical Weekly. EMH Swiss Medical Publishers Ltd.. Farnsburgerstrasse 8. CH-4132 Muttenz. Tel. +41 (0)61 467 85 55. Fax + ...
... and fundamental technology research with application in dermatology, oncology, hematology, and other specialties. ... Clinical Translational Research. 3D, colorimetric, and hyperspectral imaging of rashes. Wang et al., Proceedings of SPIE ... Vanderbilt Dermatology Translational Research Clinic (VDTRC) Making skin measurements for clinical impact.. ... The Vanderbilt Dermatology Translational Research Clinic (VDTRC) was founded in 2016 (then as the Vanderbilt Cutaneous Imaging ...
Journal of Medical Internet Research, 20 (6). e204. doi:10.2196/jmir.9779 ... Items where Department is "Faculty of Medicine , Warwick Medical School , Biomedical Sciences , Translational & Experimental ...
  • The American Journal of Translational Research is an open-access medical journal published by e-Century Publishing Corporation. (wikipedia.org)
  • Since 2009, the field has had specialized journals, the American Journal of Translational Research and Translational Research dedicated to translational research and its findings. (wikipedia.org)
  • The next intake for the MSc in Clinical & Translational Research (Full Time) is September 2018. (ucd.ie)
  • This report and a companion report published last month summarize conclusions from an August 2018 workshop co-organized by the NIH, the Radiologic American College of Radiology (ACR), the Radiological Society of North America (RSNA), and The Academy for Radiology and Biomedical Imaging Research (The Academy). (nih.gov)
  • The New Jersey Autism Center of Excellence (NJACE) at Rutgers University partnered with the Children's Specialized Hospital to create the NJACE funded by the Governor's Council for Medical Research and Treatment of Autism (Council) in 2018. (nj.us)
  • She joined the faculty at the University of Arkansas for Medical Sciences (UAMS) in 1998, where she held the position of Professor and Vice Chair for Academic Affairs until January of 2017. (uscap.org)
  • Jaroslaw Aronowski, Ph.D., professor, vice-chair and the Roy M. and Phyllis Gough Huffington Chair in Neurology at McGovern Medical School has been awarded the prestigious 2017 Thomas Willis Award for significant translational contributions to clinical stroke research by the American Heart Association. (uth.edu)
  • BMC Medical Ethics 2017, 18 (1), 24. (ncl.ac.uk)
  • Translational Health Sciences runs a programme of research talks each year from a blend of up-and-coming research stars and world-leading established researchers. (bristol.ac.uk)
  • We hope the seminars will be informative and inspirational to all staff and students in Translational Health Sciences, and also to those from other schools and departments. (bristol.ac.uk)
  • Some of this research has been extended and the findings tested in human patients and normal volunteers, in cognitive, neuroimaging and molecular epidemiological studies conducted in collaboration with our colleagues in the ReMeMBr Group and the Bristol Medical School: Population Health Sciences . (bristol.ac.uk)
  • Northwestern University Feinberg School of Medicine and the Northwestern University Clinical and Translational Sciences (NUCATS) Institute, Chicago, IL 60611, USA. (sciencemag.org)
  • T1 science seeks to move basic laboratory discoveries in the biomedical sciences to clinical research. (sciencemag.org)
  • Radiology has transformed the practice of medicine in the past century, and AI has the potential to radically impact radiology in positive ways," said Krishna Kandarpa, M.D., Ph.D., co-author of the report and director of research sciences and strategic directions at NIBIB. (nih.gov)
  • 13 Research Sciences & Strategic Directions, Office of the Director, National Institute of Biomedical Imaging and Bioengineering, The National Institutes of Health, Bethesda, Maryland. (nih.gov)
  • Professor Anna Dominiczak, Institute of Cardiovascular & Medical Sciences, University of Glasgow, chairs the Group. (ukri.org)
  • We must reinvigorate the federal-academic partnership for research across all sciences," the authors write. (eurekalert.org)
  • The pre-clinical research units in the Fraunhofer Group for Life Sciences, working in compliance with GLP guidelines, contribute with their innovative research approaches to substantial reduction of the cost and time required for developing novel diagnostics and medications. (fraunhofer.de)
  • For some indication areas, the Fraunhofer Group for Life Sciences has the expertise to cover the whole process from the molecule up to the patient, regarding both research and registration. (fraunhofer.de)
  • The Distinguished Faculty Lectureship Award in Biomedical Research is the highest honor bestowed upon a faculty member in the biomedical sciences by the Medical School. (umich.edu)
  • Our research degrees are open to students from a broad range of backgrounds, and range from basic sciences to clinical research. (edu.au)
  • ALa N, JCNa A, DSb N, TILa A, ETa K. Research & Reviews: Journal of Medical and Health Sciences. (omicsonline.org)
  • The Medical Sciences Summer Schools in 2021 will be organized online. (rug.nl)
  • The Medical Sciences Summer School program of the University Medical Center Groningen (UMCG), University of Groningen, consists of several Summer Schools encompassing a wide range of medical disciplines. (rug.nl)
  • The Medical Sciences Summer School Groningen is an initiative of the Graduate School of Medical Sciences (GSMS). (rug.nl)
  • The program provides a structured education in basic neuroscience to medical students and trains students of the natural and life sciences in medical topics concerning the central and peripheral nervous system. (gradschools.com)
  • 1 Clinical Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA. (nih.gov)
  • He became a Reader at the Institute of Cardiovascular and Medical Sciences in 2011 and is currently Professor of Cardiovascular Prevention and Deputy Director of the BHF Centre of Excellence. (gla.ac.uk)
  • As a result, there is substantial expertise within the department for specific cancers and oncogenes, as well as for interdisciplinary areas such as molecular and cellular oncology, precision cancer medicine, early drug development, immuno-oncology, population sciences and genetics, and research and clinical informatics. (dana-farber.org)
  • In a two-stage model, T1 research, refers to the "bench-to-bedside" enterprise of translating knowledge from the basic sciences into the development of new treatments and T2 research refers to translating the findings from clinical trials into everyday practice. (wikipedia.org)
  • In life-sciences, this was evidenced by a citation pattern between the applied and basic sides in cancer research that appeared around 2000. (wikipedia.org)
  • Because the prototype model at Erasmus MC surpassed even the highest expectations of researchers and clinicians, the medical center spun off a Rotterdam-based company, Crosslinks, which is now beginning to market I-space to hospitals and medical centers throughout Europe in collaboration with SGI and Barco. (thomasnet.com)
  • An important goal of the resulting road map is to grow an ecosystem, facilitated by professional societies, industry, and government agencies, that will allow robust collaborations between practicing clinicians and AI researchers to advance foundational and translational research relevant to medical imaging. (nih.gov)
  • With a focus on two main research areas - diabetes and cancer, researchers at this Institute focus on the importance of tailoring treatment protocols specifically for each patient according to their own unique personal genetics, lifestyle, and environment. (healthmagazine.ae)
  • Additionally, TIPMTR will serve as a central hub for researchers, clinicians, faculty and students interested in medical research. (healthmagazine.ae)
  • Acknowledging and addressing this mismatch of approach and lack of common language in a systematic way facilitates a more effective "translation" handoffs of academic project concepts into meaningful clinical solutions help translational researchers more efficiently develop and progress new and better medical products which address validated needs. (mdpi.com)
  • To get exposure to key research laboratories and researchers within the Harvard community and to obtain user feedback on the performance of our technology is highly valuable for us. (mynewsdesk.com)
  • The Harvard Clinical and Translational Science Center brings together the intellectual force, technologies, and clinical expertise at Harvard University and its academic, health care, and community partners to create connections, enable research at the cutting edge of discovery, and nurture clinical and translational researchers with the goal of improving human health. (mynewsdesk.com)
  • The clinical and translational research community at MMCRI is a closely-linked, multi-disciplinary scientific enterprise in which basic, clinical and translational researchers plan and conduct studies as collaborators and scientific colleagues. (mmcri.org)
  • We have established core facilities to enhance and facilitate translational research being performed by an assembled group of basic and clinical researchers at MMCRI. (mmcri.org)
  • Many of our research themes are recognized national referral centres and the clinicians and researchers are national and international leaders in their field. (lumc.nl)
  • The department provides a framework in which basic scientists, translational researchers, clinical investigators, and clinicians can pool their efforts as a team to make significant advances in understanding the pathogenesis and pathophysiology of different cancers, and on designing novel therapies for cancer. (dana-farber.org)
  • The Department of Medical Oncology recruits disease-oriented researchers who can conduct outstanding basic or clinical research as well as participate in the clinical activities of a particular clinical center. (dana-farber.org)
  • This webinar will be ideal for academic or pharmaceutical researchers who are interested in using antibody enrichment for mass spectrometry-based proteomics to study how post-translational modifications (PTMs) influence cellular growth, development, and disease biology and treatment. (xtalks.com)
  • The most promising areas of translational medical research, including CAR-T cancer therapies and stem cell-based regenerative medicine, require the isolation and purification of large numbers of viable, functional cells. (news-medical.net)
  • Quad Technologies Inc ('Quad'), developer of a novel cell separation technology, has secured a substantial amount of capital from its Series A round to accelerate development of disruptive cell processing technologies for translational medicine applications. (news-medical.net)
  • UCD School of Medicine and Medical Science. (ucd.ie)
  • MOUNTAIN VIEW, Calif., April 10 / -- To greatly enhance clinical treatment and medical research capabilities, with special emphasis on genomics data mining, proteomics data mining and translational medicine, Erasmus Medical Center added server and visualization systems from Silicon Graphics to its hospital and research facility in Rotterdam, The Netherlands. (thomasnet.com)
  • Through faculty appointments at Case Western Reserve University School of Medicine and through research conducted with support from UH's Harrington Discovery Institute, physician-scientists at UH Cleveland Medical Center are advancing medical care through education and innovative research that brings the latest treatment options to patients regionally and around the world. (uhhospitals.org)
  • You will bring a doctor of medicine (MD) and excellent research achievements to be proven by publications to the role. (zeit.de)
  • Therefore, a German medical license, board certification in internal medicine, hematology and medical oncology (or equi-valent specialist medical training), high competence and leadership experience in patient care as well as the willingness and ability to cooperate and work inter-disciplinarily are expected. (zeit.de)
  • Translational medicine has become a priority, but there is still a big difference between the arrival of new treatments and investment. (usp.br)
  • The purpose of this literature review was to analyze the translational medicine in the liver transplant field: liver ischemia-reperfusion injury (IRI), immunosuppression, clinical and surgical complications, small-for-size syndrome (SFSS), rejection, and ongoing innovations (liver machine, liver preservation, artificial livers, and regenerative medicine). (usp.br)
  • Methodological viewing and analysis of the articles, followed by the application of scientific models, including translational medicine in the liver transplant field. (usp.br)
  • In conclusions, this review demonstrates the application of scientific research with translation medical benefits regarding the LT. The literature has a great tendency, improvements and investments in the study of translational medicine in LT. Innovative studies and technologies from basic science help to clarify clinical doubts. (usp.br)
  • Through a collaboration between the University of Puerto Rico (UPR) School of Medicine and Mayo Clinic, the Center for Clinical and Translational Science (CCaTS) offers a small number of UPR medical students an opportunity to take part in a two-month clinical and translational research experience (project) with an established investigator on the Mayo Clinic campus in Rochester, Minnesota. (mayo.edu)
  • While recipients of the UPR School of Medicine Research Award receive a stipend, transportation to and housing in Rochester are not provided, though Mayo Clinic staff will assist participants in locating travel and lodging options. (mayo.edu)
  • Read more about the UPR School of Medicine Research Award's eligibility requirements and application process . (mayo.edu)
  • Health met with Dr. P. K. Menon, director of the Thumbay Institute of Precision Medicine and Translational Research (TIPMTR) who reveals cutting edge Diagnostic and research innovations within precision medicine that will Enable future wellness and optimal health. (healthmagazine.ae)
  • described translational research in medicine very well when they said: "TM [Translational medicine] as an interdisciplinary branch of the biomedical field supported by three main pillars: bench, bedside and community. (mdpi.com)
  • Unstable funding is threatening the viability of academic biomedical research in this country, according to a new paper published this week in the journal Science Translational Medicine . (eurekalert.org)
  • The University of Maryland School of Medicine was chartered in 1807 and is the first public medical school in the United States and continues today as an innovative leader in accelerating innovation and discovery in medicine. (eurekalert.org)
  • Located on the University of Maryland's Baltimore campus, the School of Medicine works closely with the University of Maryland Medical Center and Medical System to provide a research-intensive, academic and clinically based education. (eurekalert.org)
  • With 43 academic departments, centers and institutes and a faculty of more than 3,000 physicians and research scientists plus more than $400 million in extramural funding, the School is regarded as one of the leading biomedical research institutions in the U.S. with top-tier faculty and programs in cancer, brain science, surgery and transplantation, trauma and emergency medicine, vaccine development and human genomics, among other centers of excellence. (eurekalert.org)
  • The study, published in Science Translational Medicine , is the first to show how our internal body clocks regulate wound healing by skin cells and optimise healing during the day. (eurekalert.org)
  • To enable quick interaction between basic research and the clinical sector, optimal conditions for state-of-the-art translational medicine and personalized therapy are being created. (fraunhofer.de)
  • The University of Michigan Medical Innovation Center's (MIC) Fellowship Program assembles a team of talented post-graduates in medicine, engineering and business to develop medical technology ideas that will significantly impact human health. (umich.edu)
  • In support of improving patient care, Indiana University School of Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. (cloud-cme.com)
  • Translational medicine is highly qualified at our University Medical Center. (rug.nl)
  • In addition to Charité scientists, research laboratories of the Max-Delbrück-Center for Molecular Medicine, the Leibniz Institute for Molecular Pharmacology and the Max Plack Institute for Human Development contribute to the program. (gradschools.com)
  • UCD School of Medicine and Medical Science is a recognised leader in the delivery of undergraduate and specialist graduate healthcare education. (ucd.ie)
  • The 2008 Institute of Medicine report "Retooling for an Aging America: Building the Health Care Workforce" ( http://www.iom.edu/Reports/2008/Retooling-for-an-Aging-America-Building-the-Health-Care-Workforce.aspx ) emphasized the emergent need for additional health care personnel to address the medical needs of a growing population of older Americans with complex medical problems. (nih.gov)
  • In bioscience, translational research is a term often used interchangeably with translational medicine or translational science or bench to bedside. (wikipedia.org)
  • In the field of biomedicine, it is often called "translational medicine", defined by the European Society for Translational Medicine (EUSTM) as "an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, bedside and community", from laboratory experiments through clinical trials, to therapies, to point-of-care patient applications. (wikipedia.org)
  • The end point of translational research in medicine is the production of a promising new treatment that can be used clinically. (wikipedia.org)
  • Together, we are driving forward the most innovative technologies in neurosurgery - from cutting-edge neuroscience research and clinical trials to the widespread clinical implementation of our discoveries. (stanford.edu)
  • Furthermore, we have close ties to other neuroscience programs in Berlin such as the Berlin School of Mind and Brain, the Bernstein Center for Computational Neuroscience's graduate program, the International Helmholtz Research School Molecular Neurobiology and various Research Training Groups (GRK). (gradschools.com)
  • Medical Neuroscience students thus have access to a large number of research laboratories in both basic as well as in clinical research, headed by internationally acknowledged scientists. (gradschools.com)
  • Excellent basic research in neuroscience 3. (gradschools.com)
  • Within the Medical Research Profile 'Translational Neuroscience', innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles. (lumc.nl)
  • Translational Neuroscience is one of the few medical research centres in the Netherlands with a very strong patient-oriented (translational) neuroscientific research focus. (lumc.nl)
  • New building will house state-of-the-art translational research facility for obesity and diabetes. (prweb.com)
  • The Vanderbilt Dermatology Translational Research Clinic (VDTRC) was founded in 2016 (then as the Vanderbilt Cutaneous Imaging Clinic) as a platform for direct clinical translation of engineering for clinical impact in dermatology, oncology, and related specialties. (vanderbilt.edu)
  • The list of Fiscal Year 2016 Lung Cancer Research Program Investigator-Initiated Translational Research Award applications recommended for funding is for informational purposes only. (army.mil)
  • In the beginning of 2016, Dr. Menon explains that Founder President Mr. Thumbay Moideen was the key to initiate the setting up of an advanced medical innovation center. (healthmagazine.ae)
  • The report, published in the May 28, 2019, Journal of the American College of Radiology, identifies research priorities that leverage big data, the cloud, and machine learning for augmenting clinicians' image planning and use to make diagnoses or assess patients' responses to therapy. (nih.gov)
  • The first report published April 16, 2019, maps a path forward for foundational research in AI and this second report focuses on translational research necessary to deliver AI to clinical practice. (nih.gov)
  • Applications including the usual documents (curriculum vitae, copies of diplo-mas and degrees, a list of publications, external funding, proof of previous teaching activities, research concept) should be sent to Prof. Dr. Michael Baumann, Chairman and Scientific Director of the German Cancer Research Center (DKFZ) by 12.04.2019 via our online application portal. (zeit.de)
  • The annual MRC Festival of Medical Research takes place from 13-23 June 2019. (ukri.org)
  • But in recent years, this partnership has come under pressure, they say, because of decreased and variable federal funding, and because academic medical centers face shrinking revenues from clinical care. (eurekalert.org)
  • The authors note that many academic medical centers must treat the most complex and challenging patients, and often must care for patients with little means to pay for the treatment they receive. (eurekalert.org)
  • Comprised of 60 neurosurgeons and research faculty, and performing over 4000 neurosurgical operations covering the full spectrum of neurological conditions every year, we are consistently ranked among the best centers in the nation for neurosurgery. (stanford.edu)
  • Research in academic medical centers: Two threats to sustainable support. (upenn.edu)
  • citation needed] It is for these reasons that translational research is more effective in dedicated university science departments or isolated, dedicated research centers. (wikipedia.org)
  • We are a multidisciplinary team of clinicians and engineers whose mission is to seamlessly integrate patient care, clinical investigation, and fundamental technology research with application in dermatology, oncology, hematology, and other specialties. (vanderbilt.edu)
  • The program funds joint research between biomedical engineering investigators and clinicians, and supports the most promising technologies that can progress towards commercial development and enter the clinical practice. (vixiar.com)
  • Montefiore clinicians work with Wilf Family Cardiovascular Research Institute scientists to translate findings into day-to-day patient care activities with the goal of identifying novel approaches that will save and improve the lives of patients. (montefiore.org)
  • The TRI will bring scientists, clinicians, and the procedures necessary to facilitate translational research together under one roof. (prweb.com)
  • BETHESDA, MD August 16, 2011 The world's top scientists and clinicians in the human genetics field will gather to present their latest research findings at the 12th International Congress of Human Genetics (ICHG) / 61st Annual Meeting of the American Society of Human Genetics (ASHG), which will be held on October 11-15, 2011, in Montreal (Quebec), Canada, at the Montreal Convention Center. (bio-medicine.org)
  • A hub focused on population health, biostatistics, bioethics and epidemiology research. (mcw.edu)
  • Our research is focussed on the epidemiology of osteoporosis, defining optimal treatment pathways and identifying novel genetic pathways that influence osteoporosis risk. (garvan.org.au)
  • He is an internationally recognised ophthalmic clinician and scientist, with special interests in glaucoma, retinal cell biology, neuroprotection, ophthalmic epidemiology and translational ophthalmic research. (edu.au)
  • UWM Innovation Campus - World-class public-private research park that spurs strong and enduring partnerships between academia and industry leading to new products, and spinoff businesses. (mcw.edu)
  • Thus the Center for Advanced Biomedical Research and Innovation (CABRI) was inaugurated in 2014. (healthmagazine.ae)
  • This bill, which is now being developed by members of Congress, would authorize regular increases in biomedical research funding, and would include measures to reward innovation in research. (eurekalert.org)
  • An international business plan competition highlighting Michigan as a robust venue for innovation and business opportunity, the Accelerate Michigan Innovation Competition was hosted December 9-11, 2010 at the UM North Campus Research Complex. (umich.edu)
  • The topics of these curriculum units span the broad set of issues that a successful medical technology innovation must understand: regulatory approval, reimbursement strategies, intellectual property protection, marketing and distribution, animal and human subject trials, venture creation and financing. (umich.edu)
  • The Dementia Research Group is part of the University of Bristol's Institute of Clinical Neurosciences . (bristol.ac.uk)
  • Medical Neurosciences focuses on translational research. (gradschools.com)
  • Translational scientists turn science and research into improved treatments. (mcw.edu)
  • Proof of successful promotion of young scientists (especially at different levels of training of clini-cian scientists and medical scientists) is desired. (zeit.de)
  • Strong research and attractive study programmes attract scientists and students from around the world. (kdphd.com)
  • If the current trends in funding continue, both established investigators and early-career scientists could leave academic research, the authors warn. (eurekalert.org)
  • This could have implications for medical procedures such as surgery and provides targets for developing drugs that improve wound healing, according to the study led by scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, UK. (eurekalert.org)
  • The Costas T. Lambrew Research Retreat will be held on May 1, at Maine Medical Center's Dana Center, bringing together more than 200 physicians, nurses, scientists and trainees from across MaineHealth for a day-long multi-disciplinary biomedical research symposium. (mmcri.org)
  • This week's research roundup features research that detected elevated serum levels of DNAJB9 in fibrillary glomerulonephritis patients in addition to several other research articles published last week by Mayo Clinic physicians and scientists. (medpagetoday.com)
  • Cell Signaling Technology (CST) is a private, family-owned company, founded by scientists and dedicated to providing high quality research tools to the biomedical research community. (xtalks.com)
  • The National Institute on Aging (NIA) offers this initiative to promote research conducted by early stage physicians trained in medical or surgical specialties who are entering careers as clinician-scientists in aging-related aspects of their specialty. (nih.gov)
  • Effective approaches to this impending health care crisis involve not only increasing the number of practicing physicians trained in geriatrics and in specialty fields related to the health problems of elders, but also fostering the development of the next generation of physician-scientists whose clinical research will lead to improved care and more effective treatment options for older patients with complex medical conditions. (nih.gov)
  • A pivotal point in the development of clinician-scientists is the completion of training in a medical or surgical specialty and the first faculty appointment. (nih.gov)
  • Thus, mechanisms that allow these physicians to begin research projects and establish a research track record are a priority for cultivating the next generation of clinician-scientists, particularly at the interface of aging and medical/surgical specialties. (nih.gov)
  • To accomplish this goal, NIA will provide two years of support for small research projects to physicians trained in medical or surgical specialties who seek to become clinician-scientists in aging-related aspects of their specialty. (nih.gov)
  • The MSc in Clinical and Translational Research aims to train the next generation of investigators who will lead cutting edge clinical research into the future. (ucd.ie)
  • We deliver our programme through a blend of on-line learning followed by time in an active Clinical Research Centre, thereby ensuring students are taught by and gain experience alongside expert staff and internationally renowned investigators. (ucd.ie)
  • The model utilized at HC-LITT, where leading-edge technologies are put to use in the hands of investigators from diverse disciplines with the goal of addressing questions with human translational impact, will ultimately facilitate the acceptance of the Stabilizor technology. (mynewsdesk.com)
  • Investigators at the level of Assistant Professor, Instructor, or Assistant Research Professor (or equivalent) and less than 10 years from a terminal degree (excluding time spent in medical residency or family medical leave) at the time of application submission deadline are eligible. (army.mil)
  • And most clinical investigators have ties to one or more basic research laboratories or disease programs within Dana-Farber/Harvard Cancer Center (DF/HCC). (dana-farber.org)
  • The UCSF Clinical Research Center at Parnassus opened its doors on Aug. 10, providing investigators with 2,500 square feet of new adult outpatient clinical research space. (ucsf.edu)
  • The new facility has been designed specifically to support outpatient clinical research visits, providing better service to investigators in a setting that patients find comfortable. (ucsf.edu)
  • The award will provide an opportunity to gain skills and experience in aging research and help investigators establish an independent program of research in their clinical field relevant to geriatric or gerontologic science. (nih.gov)
  • Welcome to the EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY , the leading European professional organisation for medical oncology. (esmo.org)
  • The overall goal is to develop innovative clinical translational therapy concepts in personalized oncology using Investigator Initiated Trials (IITs). (zeit.de)
  • The UMCCC has a large clinical practice in sarcoma oncology, with a well-established multidisciplinary clinic and tumor board and an established track record in sarcoma clinical and basic research. (nejmcareercenter.org)
  • Excellent clinical skills appropriate for a tertiary level subspecialty sarcoma medical oncology practice are required, as well as effective communication and leadership skills, and a commitment to service excellence. (nejmcareercenter.org)
  • Applicants (who must be either U.S. citizens or resident aliens) must be board certified or eligible in medical oncology. (nejmcareercenter.org)
  • The clinician-scientist model results in increased academic productivity for Medical Oncology. (dana-farber.org)
  • The clinical research of the ReMeMBr Group is conducted in the adjacent Brain Centre. (bristol.ac.uk)
  • It is also a member of the Bristol and Bath Alzheimer's Research UK Network Centre , one of the main partners in the Brains for Dementia Research (BDR) Initiative , a member of the GW4 Aging and Dementia (GW4AD) Consortium , and a member of the European Alzheimer's Disease Consortium (EADC) . (bristol.ac.uk)
  • Affords participants the opportunity to spend time with the research teams in the UCD Clinical Research Centre to observe clinical trials in action. (ucd.ie)
  • You will be based at the UCD Clinical Research Centre, Ireland's leading centre for patient focused clinical and translational research, situated at St Vincent's and Mater Misericordiae University Hospitals. (ucd.ie)
  • There is close collaboration with the Clinical Research Facility at the Queen Elizabeth University Hospital and Prof. Delles leads the Vascular Core which is an integral part of the BHF Centre of Excellence. (gla.ac.uk)
  • The Medical College of Wisconsin is a unique free-standing medical school with 1,450 faculty and $142 million of external research support. (mcw.edu)
  • Translational Pharmacology, University of Bonn Medical Faculty, Germany. (nih.gov)
  • With approx-imate-ly 3,000 em-ployees, we operate an exten-sive scien-tific program in the field of cancer research. (zeit.de)
  • With the "DKFZ Leadership Program in Cancer Research" we aim to increase the number of highly qualified scientist (m/f/d) in leadership positions. (zeit.de)
  • Cancer Research. (elsevier.com)
  • The medical oncologists in my team are experts in specific cancer types and lead major research efforts across many cancer types, including colorectal , pancreas , prostate, breast and brain tumours. (edu.au)
  • A collaborative research program has been created to identify new treatments for patients with pancreatic cancer. (edu.au)
  • The paper notes that since World War II, the federal government and academic research institutions have formed a "remarkable collaboration" that has fostered many important research and clinical advances in many areas, including cancer, cardiovascular and neurodegenerative diseases, mental illness and infectious disease. (eurekalert.org)
  • To evaluate the impact of the National Breast Cancer Foundation's (NBCF's) research investment. (mja.com.au)
  • In 2011, Australia's total federal, state and non-government organisation spending on cancer research projects, programs and infrastructure was $300 million, of which $83 million was awarded by major national cancer research funding charities, including $9 million by the National Breast Cancer Foundation (NBCF). (mja.com.au)
  • The NBCF seeks to invest in breast cancer research that will have the greatest impact, aiming to reduce the burden of a breast cancer diagnosis for all those living with or at high risk of developing breast cancer, and their families. (mja.com.au)
  • 5 , 6 In early 2012, the NBCF's board of directors sought an independent evaluation of its total investment in breast cancer research to identify and communicate the impacts of that research to the Australian community, and to use the findings as an evidence base to inform and guide the NBCF's future funding strategies. (mja.com.au)
  • The FY17 Defense Appropriations Act provides $10 million (M) to the Department of Defense Kidney Cancer Research Program (KCRP) to support United States Army Medical Research Acquisition Activity (USAMRAA). (army.mil)
  • Supports new ideas that represent innovative, high-risk/high-gain approaches to kidney cancer research, and have the potential to make an important contribution to kidney cancer. (army.mil)
  • The synergy among basic investigation, clinical research, translational development, and cancer care is a fundamental characteristic of the department - connecting basic research to significant clinical challenges, and allowing clinical observation to inform the work at the lab bench. (dana-farber.org)
  • The Dementia Research Group conducts laboratory-based (preclinical) research that translates into clinical research in dementia. (bristol.ac.uk)
  • Our laboratory-based research is almost exclusively undertaken in the Learning & Research building, at Southmead Hospital, Bristol. (bristol.ac.uk)
  • Downstream goals of medical education research are to demonstrate that educational interventions contribute to physician competence measured in the classroom, educational laboratory, and patient care setting. (sciencemag.org)
  • i) These interventions focus on learning objectives grounded in behavioral descriptions of expert clinical performance derived from experience or laboratory research ( 2 ). (sciencemag.org)
  • iii) The educational interventions use a medical simulation center or laboratory to allow deliberate practice with feedback in a controlled, forgiving environment using devices that vary in fidelity depending on target learning objectives ( 5 , 6 ). (sciencemag.org)
  • At University Hospitals Translational Laboratory we aim for the development of assays based on the latest technology. (uhhospitals.org)
  • By working across the spectrum, from small animals to human subjects, this area of research transforms laboratory observations into actual treatments for individuals and the public. (osu.edu)
  • Translational research for new drugs, medical devices, and diagnostics encompasses aspects of both basic science and clinical research, requiring multidisciplinary skills and resources that are not all readily available in either a basic laboratory or clinical setting alone. (mdpi.com)
  • Laboratory for Innovative Translational. (mynewsdesk.com)
  • A central component of Harvard Catalyst, a primary goal of HC-LITT is to provide the Harvard research community with early access to new, enabling, leading-edge technologies, LITT hope to accelerate the translation of laboratory research in therapeutics and diagnostics into the clinic. (mynewsdesk.com)
  • The Clinical Glaucoma Research and Ophthalmic Research Laboratory undertakes groundbreaking research on retinal cell biology and glaucoma, with translation into clinical trials. (edu.au)
  • Tumors of the Bones and Joints and 4th edition of the WHO Classification of Tumours of Soft Tissue and Bone ) and directs a research laboratory focused on molecular profiling of solid tumors and molecular test development. (uscap.org)
  • Based on their genotypes, subjects are invited to participate at all levels of research, from basic laboratory ex vivo cell phenotyping experiments that require viable tissue to in vivo observational studies and clinical trials. (nih.gov)
  • In turn, the findings gained through clinical research help to take laboratory investigations in new directions. (bidmc.org)
  • The adjective "translational" refers to the "translation" (the term derives from the Latin for "carrying over") of basic scientific findings in a laboratory setting into potential treatments for disease. (wikipedia.org)
  • T0 is laboratory (before human) research. (wikipedia.org)
  • The Research Park will nurture technology-based companies, strengthen Milwaukee County's business base, create new employment opportunities, and facilitate technology commercialization. (mcw.edu)
  • The EPR is a phenotype-by-genotype resource designed to facilitate translational studies of environmental disease. (nih.gov)
  • The Transition Support pilot scheme will help facilitate the transition of existing intermediate MRC fellows to research leadership positions. (ukri.org)
  • The Translational Pain Research Program conducts leading edge clinical research across the spectrum of acute, peri-operative, and chronic pain conditions. (rochester.edu)
  • The program draws on the resources of the university to conduct investigator- initiated research designed to address key roadblocks to the development of new pain relievers and conducts Phase I - IV clinical studies in collaboration with industry partners. (rochester.edu)
  • Transplant surgeon Ginny Bumgardner, MD, PhD, conducts transplant immunology research, motivated by the power of transplantation to transform the lives of patients with end-stage organ failure. (osu.edu)
  • Our 19 clinical divisions and programs deliver compassionate care informed by the most advanced standards of care and multidisciplinary research. (dana-farber.org)
  • This transition stage may be particularly difficult for a specialty-trained physician focusing on aging-related aspects of his/her specialty, as multidisciplinary research entails training that is rarely available in conventional programs. (nih.gov)
  • This Commentary covers features of medical education interventions and environments that contribute to translational outcomes, reviews selected research studies that advance translational science in medical education at all three levels, and presents pathways to improve medical education translational science. (sciencemag.org)
  • Improved patient outcomes linked directly to educational events are the ultimate goal of medical education research. (sciencemag.org)
  • These investigations address skill and knowledge acquisition and maintenance by individual physicians and health care teams chiefly in simulation laboratories that provide postgraduate education and in continuing medical education (CME) programs, the application and transfer of acquired skill and knowledge to patient care, and improved patient outcomes that occur as a result of educational practices ( Table 1 ). (sciencemag.org)
  • Contributions of medical education interventions to T1, T2, and T3 outcomes. (sciencemag.org)
  • thereby defining the new standard of patient care by improving outcomes and reducing costs at Lahey Hospital & Medical Center. (lahey.org)
  • Further research into the link between body clocks and wound healing may help us to develop drugs that prevent defective wound healing or even help us to improve surgery outcomes. (eurekalert.org)
  • This research is awarded by the Patient Centered Outcomes Research Institute (PCORI). (mmcri.org)
  • The mission of the research is to further our understanding of cystic fibrosis and develop therapies to improve outcomes for CF patients. (mmcri.org)
  • 1 With growing competition for the charity dollar, it is becoming increasingly important for medical research charities to demonstrate the outcomes or benefits of the research that they fund and to identify research strategies that are most likely to produce future benefits. (mja.com.au)
  • The goal of the Autism Health Needs Medical Homes Pilot Projects, under the direction of the NJACE Children's Specialized Hospital, is to improve the overall health outcomes of children with autism by improving the quality of and access to services for children and their families. (nj.us)
  • Montefiore's Comprehensive Heart Valve Repair Program is advancing the treatment of complex valve disease through groundbreaking clinical and translational research. (montefiore.org)
  • As a member of the prestigious Cardiothoracic Surgical Trials Network (CTSN) the Heart Valve Repair Program plays a leading role in national proof-of-concept and translational research trials. (montefiore.org)
  • All patients in the Heart Valve Repair Program are evaluated for inclusion in clinical trials that explore promising new medical therapies or devices. (montefiore.org)
  • MMC's Cystic Fibrosis Research Program directed by Dr. Ana Cairns (Pediatrics) and Dr. Jonathan Zuckerman (Adult) currently has 10 active clinical trials, which comprise a blend of industry, federal, and foundation-funded studies. (mmcri.org)
  • At a minimum, each MIC Fellows exits the program with a strong understanding of all the aspects of medical technology development and commercialization. (umich.edu)
  • Throughout the program, the Fellows develop personal relationships with industry leaders and mentors who comprise a medical technology ecosystem upon which they can draw in the future. (umich.edu)
  • As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA) J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. (army.mil)
  • The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP). (army.mil)
  • In addition to supporting research and treatment of autism, the Department of Health assists families affected by autism through its Early Intervention Services program . (nj.us)
  • Besides in depth theoretical training, the MSc program emphasizes practical lab experience, preparing graduates for continued research as PhD students. (gradschools.com)
  • The program is very research driven. (gradschools.com)
  • Intense theoretical training combined with extensive practical lab work, preparing you perfectly for a PhD program and subsequent research career 4. (gradschools.com)
  • This program is intended for early career physicians trained in medical or surgical specialties to establish a research track record in aging-related aspects of their specialty. (nih.gov)
  • The goal of the Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) program is to promote future leaders in clinical aging research across the range of medical and surgical specialties. (nih.gov)
  • Beth Israel Deaconess Medical Center (BIDMC) is home to a preeminent academic research program where scientific discoveries are helping to transform medical care. (bidmc.org)
  • BIDMC's research program is truly translational. (bidmc.org)
  • Knopp RH: Test of the Lipid Hypothesis: The Coronary Primary Prevention Trial (CPPT) of the Lipid Research Clinics Program. (clinicaltrials.gov)
  • The mission of the NIOSH Small Business Assistance Program is to decrease occupational diseases, injuries, and fatalities in smaller business es by encouraging and supporting research, outreach, and prevention activities. (cdc.gov)
  • The Translational Genome Informatics team is working on improved methods for comprehensive genome characterisation. (garvan.org.au)
  • BMC Medical Informatics and Decision Making. (elsevier.com)
  • Future research investigating the role of host genetics on gut microbiota might therefore lead to identification of diagnostic and therapeutic targets for MetS. (nature.com)
  • To assist clinical laboratories with the validation of next-generation sequencing methods and platforms, the ongoing monitoring of next-generation sequencing testing to ensure quality results, and the interpretation and reporting of variants found using these technologies, the American College of Medical Genetics and Genomics has developed the following professional standards and guidelines. (nih.gov)
  • The Society's Annual Meeting is the world's largest gathering of human genetics professionals and a forum for renowned experts in the field to share their latest research results. (bio-medicine.org)
  • With more than 300 platform and plenary presentations, 3,500 posters, 24 invited sessions, special symposia and panel debate sessions, as well as onsite press briefing events that will be webcast to the media, the ICHG/ASHG 2011 Meeting will provide journalists with information on the most important and recent developments in human genetics and genomics research. (bio-medicine.org)
  • Dr. Bridge earned her MD from the University of Nebraska Medical Center and completed her pathology residency at the University of Kansas Medical Center followed by clinical cytogenetic and molecular fellowships at the University of Nebraska Medical Center and the Southwest Biomedical Research Institute in Scottsdale Arizona. (uscap.org)
  • The Medical Center for Translational and Clinical Research supports the clinical application of these new treatment methods at the research stage, and also promotes the development of new therapies. (hiroshima-u.ac.jp)
  • Erasmus University Medical Center (Erasmus MC) has developed 3D volume rendering software, capable of converting 2D medical images to 3D. (thomasnet.com)
  • For the commercial launch of the I-space model, the medical center selected Barco projectors and Silicon Graphics Prism(TM) visualization systems as image generators to create the four-sided, 3x3x3- metre, 3D world intended for multidisciplinary collaboration. (thomasnet.com)
  • University Hospitals Cleveland Medical Center is the flagship academic medical center at the core of UH's 18 hospital health system that serves patients across northern Ohio. (uhhospitals.org)
  • Its campus research partners include Froedtert Hospital, Children's Hospital Health System of Wisconsin, VA Medical Center, and the Blood Research Institute, and the major academic institutions in southeast Wisconsin: Marquette University, University of Wisconsin-Milwaukee, and Milwaukee School of Engineering. (mcw.edu)
  • Vixiar Medical, Inc. announced today that Robert Storey, Maryland Managing Director of VIC Technology Venture Development™ and the Chairman of Vixiar Medical, was a presenter at the Coulter Foundation Investor Forum held at Stanford University's Francis C. Arrillaga Alumni Center in Palo Alto, California. (vixiar.com)
  • Albert Einstein College of Medicine's Wilf Family Cardiovascular Research Institute is a school-wide center created to unite and integrate cardiovascular research at Einstein and Montefiore. (montefiore.org)
  • The Harvard Clinical and Translational Science Center that will give the Harvard research community access to the company's StabilizorTM system for stabilizing biological samples. (mynewsdesk.com)
  • Harvard Catalyst is supported by a Clinical and Translational Science Award from the National Center for Research Resources, a component of the National Institutes of Health, as well as commitments from its partner organizations. (mynewsdesk.com)
  • With the tripod of research, education and patient care as the center of our endeavor, we are forging the interdisciplinary divide between clinical, translational, and basic research. (mmcri.org)
  • Interested in Cedars-Sinai Medical Center? (petersons.com)
  • Cedars-Sinai Medical Center / Graduate Programs is located in Los Angeles, CA, in an urban setting. (petersons.com)
  • Phoenix AZ) and the University of Nebraska Medical Center. (uscap.org)
  • The GSMS is the largest Graduate School of the University of Groningen, it is responsible for all Research Masters and PhD education programmes within the University Medical Center Groningen (UMCG). (rug.nl)
  • Boxer has four active research protocols supported at the UCSF Clinical Research Center at Parnassus focused on experimental treatments for a variety of neurodegenerative diseases. (ucsf.edu)
  • UCSF Medical Center and Clinical Research Services (CRS) partnered to open the clinic. (ucsf.edu)
  • The companion reports-co-authored by government, industry, academia and radiology specialty society leaders-have identified and prioritized initiatives to accelerate foundational and translational research in AI for medical imaging. (nih.gov)
  • The conclusions of that meeting are summarized in two publications that identify and prioritize initiatives to accelerate foundational and translational research in AI for medical imaging. (nih.gov)
  • The Scheme is designed to build research capability and accelerate evidence translation within the NSW public health system. (nsw.gov.au)
  • Their research is a combination of bioinformatic method development, applied to a number of rare conditions, including renal, cardiac, mitochondrial, epilepsy and movement disorders. (garvan.org.au)
  • MG53 is a key component of the cell membrane repair machinery - research and development efforts support the therapeutic potential for MG53 in treatment of degenerative diseases. (osu.edu)
  • The Milwaukee County Research Park Corporation (MCRPC) is a non-profit organization created to manage the development of a university-related research park on 175 acres of Milwaukee County owned land in Wauwatosa, Wisconsin. (mcw.edu)
  • Vixiar Medical, Inc, is involved in the development of innovative technologies for the treatment and monitoring of cardiopulmonary disease. (vixiar.com)
  • To provide next-generation health care solutions," the authors write, "we require 21st-century policies that support modern scientific research and development. (eurekalert.org)
  • Review concepts around translational research development of biomarkers of AKI. (mcw.edu)
  • Whether or not research should be continued can thus be decided at an early stage of drug development. (fraunhofer.de)
  • The medical member of the Fellowship Class typically returns to his/her practice area, but with skills that will enable the identification and development of medical technology ideas to impact human health. (umich.edu)
  • Research impact on knowledge production, the research system, informing policy, product development and broader health and economic benefits. (mja.com.au)
  • Protein post-translational modifications (PTMs) regulate all aspects of cellular growth, development, and disease biology. (xtalks.com)
  • The Steven P. Gygi lab is located at Harvard Medical School in Boston, MA and is a leader in the development and application of quantitative mass spectrometry methods for the analysis of biological systems. (xtalks.com)
  • You will provide medical and scientific leadership and expertise in a role that significantly impacts the entire Novartis Dermatology drug development pipeline. (novartis.com)
  • Communicate clinical team matters to Global Project Teams, relevant Novartis Institutes of BioMedical Research and Global Drug Development boards, and other Novartis Boards as required. (novartis.com)
  • Based on your own research projects as well as within multidisciplinary teams, you will be responsible for translating innovative research approaches into clinical translational trials which will be carried out in the newly established trial unit. (zeit.de)
  • Traditional approaches to evaluating the benefits of health and medical research focus on impacts on knowledge production and the research system. (mja.com.au)
  • His interests are focussed on the pathophysiology of cardiovascular diseases where he uses clinical and translational approaches in his research. (gla.ac.uk)
  • The team at TIPMTR focuses on the major health concerns facing the UAE for which Dr. Menon explains, "Diabetes was a big area which required its own designated diagnostic and research lab. (healthmagazine.ae)
  • Additionally, research focuses on disorders such as Huntington and Parkinson disease, with progressive movement impairments caused by a dysfunction of the central brain control. (lumc.nl)
  • For instance, basic biomedical research focuses on studies of disease processes using, for example, cell cultures or animal models without consideration of the potential utility of that information. (wikipedia.org)
  • While I-space, in theory, could be used for various virtual reality applications the proprietary software is specifically targeted to the medical and biology fields. (thomasnet.com)
  • The focus of Dr. Jianjie Ma's research group is simple: They want to understand the biology behind the repair of injured tissues of vital organs and translate their basic findings into treatment of human diseases. (osu.edu)
  • Successful candidates will have a strong background in translational research, particularly in lab-based research focused on sarcoma biology and therapeutics, as well as a track record of peer-reviewed publications and extramural funding reflecting an emphasis on translational accomplishments. (nejmcareercenter.org)
  • From 1999 - 2009, Sanford-Burnham ranked #1 worldwide among all types of organizations in the fields of biology and biochemistry for the impact of its research publications, defined by citations per publication, according to the Institute for Scientific Information. (prweb.com)
  • Our research groups have developed cutting edge models for neuronal and muscle (patho)biology. (lumc.nl)
  • At both places, he conducted lab and animal research, showing a keen interest in liver biology. (wikipedia.org)
  • Although advances in foundational research are occurring rapidly, translation to routine clinical practice has been slower. (nih.gov)
  • Moreover, evidence increases the importance of scientific research in quality of clinical practice care. (usp.br)
  • A hallmark of all Summer Schools is the combination of clinical practice and research. (rug.nl)
  • Stakeholders throughout the biopharmaceutical, academic, scientific research, advocacy, and clinical practice communities are welcome to participate in the survey . (nih.gov)
  • Dedicated to patient quality and clinical effectiveness, UT Physicians is the clinical practice of McGovern Medical School. (uth.edu)
  • In the field of education, it is defined for school-based education by the Education Futures Collaboration (www.meshguides.org) as research which translates concepts to classroom practice. (wikipedia.org)
  • where in it aims to "translate" findings in fundamental research into practice. (wikipedia.org)
  • DehydroalanylGly, a new post translational modification resulting from" by Michael G. Friedrich, Zhen Wang et al. (edu.au)
  • A new report , with contributions from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the National Institutes of Health, provides a roadmap for translational research on artificial intelligence (AI) in medical imaging. (nih.gov)
  • Discover our science and take a tour of the Institute: hear about our breakthroughs, journey inside the body, and understand the latest in medical research. (garvan.org.au)
  • The Garvan Institute of Medical Research has pioneered insights into some of the most widespread diseases affecting our community today. (garvan.org.au)
  • The Garvan Institute of Medical Research (ABN 62 330 391 937) and the Garvan Research Foundation (ABN 91 042 722 738) are registered charities. (garvan.org.au)
  • The Methodology Research Programme , in partnership with the National Institute for Health Research (NIHR). (ukri.org)
  • TIPMTR is an extremely scientific and focused diagnostic precision medical institute and Dr. Menon stresses that this is a very niche emerging area for research and diagnosis. (healthmagazine.ae)
  • As the prevalence of diabetes continues to increase at alarming rates affecting more than 24 million Americans, the creation of the Florida Hospital - Sanford Burnham Translational Research Institute for Metabolism and Diabetes (TRI) will take the prevention, diagnosis, and treatment of diabetes and obesity to the next level. (prweb.com)
  • The Florida Hospital-Sanford-Burnham Translational Research Institute for Metabolism and Diabetes (TRI) is the product of an innovative affiliation between Florida Hospital and Sanford-Burnham Medical Research Institute. (prweb.com)
  • Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. (prweb.com)
  • The Institute ranks among the top independent research institutions nationally for NIH grant funding and among the top organizations worldwide for its research impact. (prweb.com)
  • 1 William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, United Kingdom. (nih.gov)
  • 3 Translational Research Institute, Brisbane, QLD. (mja.com.au)
  • Medical education at all levels aims to equip physicians with the knowledge, skills, and attributes of professionalism needed to deliver quality patient care. (sciencemag.org)
  • The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. (mcw.edu)
  • Basic science should not be neglected because the translation from basic research is not sustained in the absence of basic research. (usp.br)
  • It is here that much of the cardiovascular-related basic, translational and population-based research takes place. (montefiore.org)
  • We propose that, to be successful, "translational" research ought to be understood as a defined process from basic science through manufacturing, regulatory, clinical testing all the way to market. (mdpi.com)
  • By linking one of the largest not-for-profit hospitals in the country with a nationally renowned basic science leader, the TRI bridges the gap between the research bench and the patient's bedside. (prweb.com)
  • The Purpose of this conference is to provide attendees with access to cutting edge clinical and basic science research in the fields of clinical nephrology and transplantation, renal physiology and pharmacology, and renal pathology and immunology. (mcw.edu)
  • The NBCF's research investment strategy supports a commitment to funding across the research continuum from basic to applied research, and the translation of research into clinical settings. (mja.com.au)
  • The work carried out at the NJACE supports the Council's commitment to advance and disseminate the understanding, treatment, and management of Autism Spectrum Disorder (ASD) by (1) supporting and stimulating basic and clinical ASD research and (2) providing a statewide system of training and continuing education programs for health care professionals to improve the clinical care of children, adolescents and adults with ASD. (nj.us)
  • From basic science to clinical research, we are constantly pushing scientific boundaries and earning worldwide recognition for our discoveries. (ucsf.edu)
  • Basic research to study fundamental life processes at the molecular level routinely informs clinic research. (bidmc.org)
  • In a five-stage scheme, T1 involves basic research, T2 involves pre-clinical research, T3 involves clinical research, T4 involves clinical implementation, and T5 involves implementation in the public health sphere. (wikipedia.org)
  • Basic research is the systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena and is performed without thought of practical ends. (wikipedia.org)
  • Critics of translational medical research (to the exclusion of more basic research) point to examples of important drugs that arose from fortuitous discoveries in the course of basic research such as penicillin and benzodiazepines, and the importance of basic research in improving our understanding of basic biological facts (e.g. the function and structure of DNA) that go on to transform applied medical research. (wikipedia.org)
  • You will undertake modules that will give you important skills in research, which you can use to develop your own research activities. (ucd.ie)
  • You will develop a clinical trial protocol and gain experience in critically appraising clinical research. (ucd.ie)
  • Their goal is to translate their research into effective treatments for large populations, who might otherwise develop blindness or flow-obstructing vascular diseases. (osu.edu)
  • A generous start up package and protected time will be provided to pursue research interests and develop a clinical research portfolio. (nejmcareercenter.org)
  • They can choose from a very broad spectrum of research fields ranging from molecular neurobiology to cognition and neurodegenerative diseases and develop their individual focus accordingly. (gradschools.com)
  • Research on medical education aims to make the enterprise more effective, efficient, and economical. (sciencemag.org)
  • A growing body of medical education research expands the definition of T1 to T3 translational science. (sciencemag.org)
  • This Commentary describes educational interventions that contribute to translational science, presents a selected set of T1 to T3 medical education research reports, and concludes with suggestions about ways to increase the quality of medical education translational science. (sciencemag.org)
  • Medical education interventions that contribute to T1 to T3 clinical translational science have several key features. (sciencemag.org)
  • Excellence in Education & Research. (ucd.ie)
  • We support translational research across our funding Boards and Panels, through partnerships with other funders and major Higher Education Institutions and through dedicated funding schemes. (ukri.org)
  • The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. (kdphd.com)
  • The Medical College of Wisconsin designates this activity for up to 1.0 hours of participation for continuing education for allied health professionals. (mcw.edu)
  • She was recognized at graduation seven times by the UAMS fourth year medical students for her contributions to education. (uscap.org)
  • The NJACE is creating an innovative collaborative network across New Jersey using existing programs and leveraging the leadership's extensive network to build and disseminate new innovative initiatives for research, education and service serving individuals with autism across their lifespans. (nj.us)
  • 3 Meeting these demands and expectations will be possible only with substantial effort in research and education as part of health service delivery. (mja.com.au)
  • Separation of funding for research and education from the delivery of patient care diminishes the opportunity for mutually enhancing integration, and for expenditure efficiencies. (mja.com.au)
  • Examples of translational research are commonly found in education subject association journals and in the MESHGuides which have been designed for this purpose. (wikipedia.org)
  • The Heart Valve Repair Program's commitment to advancing medical technologies gives patients access to innovative treatments that are not yet offered by other heart programs. (montefiore.org)
  • These staggering statistics call for decisive action and that includes innovative research. (prweb.com)
  • Our highly innovative research covers a number of areas. (edu.au)
  • Many departments within our Medical Research Profile perform research in the pharmacology arena, either by identifying novel drug targets or conducting clinical trials with "conventional" or "biological" drugs. (lumc.nl)
  • All the selected studies on the management of translational medical research in liver transplantation (LT) were analyzed. (usp.br)
  • Here, specialists supported by major government agencies including the National Institutes of Health (NIH), the U.S. Department of Defense and the National Aeronautics and Space Administration, apply decades of research experience to national multicenter trials and industry-funded studies. (montefiore.org)
  • Proposed research studies should have a high probability of revealing new avenues of investigation. (umaryland.edu)
  • Responsible for implementing studies during the Proof of Concept phase by providing medical and scientific leadership and expertise to all line functions on the project team. (novartis.com)
  • Sanford-Burnham, with operations in California and Florida, is one of the fastest-growing research institutes in the country. (prweb.com)
  • The Netherlands-based Intravacc is one of the world's leading institutes for translational vaccinology. (pharmiweb.com)
  • Translational science progresses from bench to bedside in at least three seamless phases. (sciencemag.org)
  • The CTSI is supported by an NIH Clinical and Translational Science Award grant. (mcw.edu)
  • Starzl attended Northwestern University Medical School in Chicago , where in 1950 he received a Master of Science degree in anatomy and in 1952 earned both a Ph.D. in neurophysiology and an M.D. with distinction. (wikipedia.org)
  • Borda A, Gray K, Fu Y. Research data management in health and biomedical citizen science: practices and prospects. (jmir.org)
  • Science Translational Magazine 7(289): 1-3, May 2015. (upenn.edu)
  • The journal covers translational research of medical science and the relevant biomedical research areas. (wikipedia.org)
  • Applied research is a form of systematic inquiry involving the practical application of science. (wikipedia.org)
  • Equips participants with the knowledge, skills and competencies to allow them to complete programmes of clinical investigation and translational research. (ucd.ie)
  • Research, including clinical investigation, is a core mission of UCSF, and providing services and facilities is essential to ensure that we achieve that mission. (ucsf.edu)
  • Biomedical translational research adopts a scientific investigation/ enquiry into a given problem facing medical/health practices to surmount such problems. (wikipedia.org)
  • Department members lead fellowship and training programs, Harvard Medical School clerkships and courses, and professional tutorials. (dana-farber.org)
  • Christopher Rose is a postdoctoral research fellow at Harvard Medical School in the lab of Steven P. Gygi, where he works on developing and applying the latest quantitative mass spectrometry methods. (xtalks.com)
  • A 30 credit research project is included in year 2 of the programme). (ucd.ie)
  • Throughout the programme you will gain significant practical experience and real world understanding of clinical research in action. (ucd.ie)
  • Fill in your personal details, and when asked about the "Programme Choice", select Masters in Clinical & Translational Research X789. (ucd.ie)
  • The Biomedical Catalyst , an integrated translational funding programme jointly operated with Innovate UK (formerly the Technology Strategy Board). (ukri.org)
  • The new clinic is ideal because it is optimized for conducting clinical research. (ucsf.edu)
  • The recipient of this award is an exceptional leader in research, whose landmark contributions are recognized both nationally and internationally. (umich.edu)
  • Driven by dedication to excellent medical care, compassion for our patients, and advancing fundamental and translational research. (stanford.edu)
  • Artificial intelligence has an expanding role to play in medical imaging. (nih.gov)
  • This roadmap is a timely survey and analysis by experts at federal agencies and among our industry and professional societies that will help us take the best advantage of AI technologies as they impact the medical imaging field. (nih.gov)
  • While most attention is drawn to the power of computers to aid in interpreting images, there is ongoing research on AI applications that address every aspect of the imaging process, according to the report. (nih.gov)
  • Advances in machine learning in medical imaging are occurring at a rapid pace in research laboratories both at academic institutions and in industry. (nih.gov)
  • Furthermore, we are working on multi-scale biomedical data fusion methods, bridging the molecular using omics data, cellular using pathology data and tissue using medical imaging data. (stanford.edu)
  • CTLA-4 blockade in tumor models: an overview of preclinical and translational research. (nih.gov)

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