Any device or element which converts an input signal into an output signal of a different form. Examples include the microphone, phonographic pickup, loudspeaker, barometer, photoelectric cell, automobile horn, doorbell, and underwater sound transducer. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Transducers that are activated by pressure changes, e.g., blood pressure.
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
Photosensory rhodopsins found in microorganisms such as HALOBACTERIA. They convert light signals into biochemical information that regulates certain cellular functions such as flagellar motor activity.
A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.
The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.
A cytokine receptor that acts through the formation of oligomeric complexes of itself with a variety of CYTOKINE RECEPTORS.
A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues.
A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
The major protein constituents of milk are CASEINS and whey proteins such as LACTALBUMIN and LACTOGLOBULINS. IMMUNOGLOBULINS occur in high concentrations in COLOSTRUM and in relatively lower concentrations in milk. (Singleton and Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed, p554)
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. SOCS proteins contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-4. Stat6 has been shown to partner with NF-KAPPA B and CCAAT-ENHANCER-BINDING PROTEINS to regulate GENETIC TRANSCRIPTION of interleukin-4 responsive GENES.
Methods of creating machines and devices.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
Light driven chloride ion pumps that are ubiquitously found in halophilic archaea (HALOBACTERIALES).
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
The use of focused, high-frequency sound waves to produce local hyperthermia in certain diseased or injured parts of the body or to destroy the diseased tissue.
A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
The branch of physics that deals with sound and sound waves. In medicine it is often applied in procedures in speech and hearing studies. With regard to the environment, it refers to the characteristics of a room, auditorium, theatre, building, etc. that determines the audibility or fidelity of sounds in it. (From Random House Unabridged Dictionary, 2d ed)
Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.
A genus of rod-shaped, extremely halophilic HALOBACTERIACEAE which grows in alkaline conditions. They are strictly aerobic and some strains are motile. Natronobacterium is found in soda lakes, alkaline salterns, and soda soils.
The use of focused, high-frequency sound waves to destroy tissue. It is sometimes used in conjunction with but is distinct from INTERVENTIONAL ULTRASONOGRAPHY.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitogen-activated B-LYMPHOCYTES, and peripheral MONOCYTES. The receptors are heterodimers of the INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.
A cell line derived from cultured tumor cells.
A species of halophilic archaea found in salt lakes. Some strains form a PURPLE MEMBRANE under anaerobic conditions.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Established cell cultures that have the potential to propagate indefinitely.
Proteins found in any species of archaeon.
The design or construction of objects greatly reduced in scale.
A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
A Janus kinase subtype that is predominantly expressed in hematopoietic cell. It is involved in signaling from a broad variety of CYTOKINE RECEPTORS including ones that utilize the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT.
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics.
Processes that stimulate the GENETIC TRANSCRIPTION of a gene or set of genes.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Non-invasive imaging methods based on the mechanical response of an object to a vibrational or impulsive force. It is used for determining the viscoelastic properties of tissue, and thereby differentiating soft from hard inclusions in tissue such as microcalcifications, and some cancer lesions. Most techniques use ultrasound to create the images - eliciting the response with an ultrasonic radiation force and/or recording displacements of the tissue by Doppler ultrasonography.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
The movement of cells or organisms toward or away from a substance in response to its concentration gradient.
Small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
A semi-synthetic aminoglycoside antibiotic that is used in the treatment of TUBERCULOSIS.
Fenestra of the cochlea, an opening in the basal wall between the MIDDLE EAR and the INNER EAR, leading to the cochlea. It is closed by a secondary tympanic membrane.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
Cell surface proteins that bind interleukins and trigger intracellular changes influencing the behavior of cells.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)
The lymph fluid found in the membranous labyrinth of the ear. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Investigative and diagnostic methods and procedures based on the photoacoustic effect, which is the generation of SOUND WAVES from the absorption of ELECTROMAGNETIC RADIATION.
An implant used to replace one or more of the ear ossicles. They are usually made of plastic, Gelfoam, ceramic, or stainless steel.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Elements of limited time intervals, contributing to particular results or situations.
Specific molecular sites or structures on or in cells with which interferons react or to which they bind in order to modify the function of the cells. Interferons exert their pleiotropic effects through two different receptors. alpha- and beta-interferon crossreact with common receptors, while gamma-interferon initiates its biological effects through its own specific receptor system.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behavior of cells.
Electronic devices that increase the magnitude of a signal's power level or current.
A genus of HALOBACTERIACEAE whose growth requires a high concentration of salt. Binary fission is by constriction.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the COCHLEA. Towards the cochlear apex, the length of hair cell bodies and their apical STEREOCILIA increase, allowing differential responses to various frequencies of sound.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
A class of devices combining electrical and mechanical components that have at least one of the dimensions in the micrometer range (between 1 micron and 1 millimeter). They include sensors, actuators, microducts, and micropumps.
Proteins prepared by recombinant DNA technology.
Transport proteins that carry specific substances in the blood or across cell membranes.
Rhodopsins found in the PURPLE MEMBRANE of halophilic archaea such as HALOBACTERIUM HALOBIUM. Bacteriorhodopsins function as an energy transducers, converting light energy into electrochemical energy via PROTON PUMPS.
Glycoproteins found on the membrane or surface of cells.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
Hearing loss due to damage or impairment of both the conductive elements (HEARING LOSS, CONDUCTIVE) and the sensorineural elements (HEARING LOSS, SENSORINEURAL) of the ear.
Proteins found in any species of bacterium.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Use of reflected ultrasound in the diagnosis of intracranial pathologic processes.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Cell surface receptors formed from the dimerization of LIF RECEPTOR ALPHA SUBUNIT with CYTOKINE RECEPTOR GP130. Although originally described as receptors for LEUKEMIA INHIBITORY FACTOR these receptors also bind the closely-related protein ONCOSTATIN M and are referred to as both LIF receptors and type I oncostatin M receptors.
Gated transport mechanisms by which proteins or RNA are moved across the NUCLEAR MEMBRANE.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
LIGHT, it's processes and properties, and the characteristics of materials interacting with it.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
An interferon regulatory factor that recruits STAT1 PROTEIN and STAT2 PROTEIN heterodimers to interferon-stimulated response elements and functions as an immediate-early protein.
The motor activity of the GASTROINTESTINAL TRACT.
Rhodopsin molecules found in microorganisms such as ARCHAEA and PROTEOBACTERIA.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
The aggregation of soluble ANTIGENS with ANTIBODIES, alone or with antibody binding factors such as ANTI-ANTIBODIES or STAPHYLOCOCCAL PROTEIN A, into complexes large enough to fall out of solution.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.
Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.
Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.
Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Endogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= PLANT GROWTH REGULATORS).
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Imaging the temperatures in a material, or in the body or an organ. Imaging is based on self-emanating infrared radiation (HEAT WAVES), or on changes in properties of the material or tissue that vary with temperature, such as ELASTICITY; MAGNETIC FIELD; or LUMINESCENCE.
A neurotrophic factor that promotes the survival of various neuronal cell types and may play an important role in the injury response in the nervous system.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Triterpenes that derive from LANOSTEROL by a shift of the C19 methyl to the C9 position. They are found in seeds and roots of CUCURBITACEAE and other plants and are noted for intense bitterness.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.
An electrophoretic technique for assaying the binding of one compound to another. Typically one compound is labeled to follow its mobility during electrophoresis. If the labeled compound is bound by the other compound, then the mobility of the labeled compound through the electrophoretic medium will be retarded.
Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Enzymes that oxidize certain LUMINESCENT AGENTS to emit light (PHYSICAL LUMINESCENCE). The luciferases from different organisms have evolved differently so have different structures and substrates.
Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells' physiological response to that hormone. Mammary casein synthesis is one of the responses. The receptors are also found in placenta, liver, testes, kidneys, ovaries, and other organs and bind and respond to certain other hormones and their analogs and antagonists. This receptor is related to the growth hormone receptor.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
Restoration, reconstruction, or improvement of a defective or damaged LARYNX.
Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest.
The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The process by which two molecules of the same chemical composition form a condensation product or polymer.
CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CERCOPITHECUS AETHIOPS).)
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Projection of near-IR light (INFRARED RAYS), in the 700-1000 nm region, across an object in parallel beams to an array of sensitive photodetectors. This is repeated at various angles and a mathematical reconstruction provides three dimensional MEDICAL IMAGING of tissues. Based on the relative transparency of tissues to this spectra, it has been used to monitor local oxygenation, brain and joints.
Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons consisting of a polyisoprene backbone.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
Cell surface receptors with specificity for ONCOSTATIN M. Two subtypes of receptors have been identified and are defined by their subunit composition.
Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.
A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.
Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures. (1/1232)

We studied phasic right coronary blood flow in well trained normal dogs and dogs with pulmonic stenosis. We installed electromagnetic flow transducers and pressure tubes under anesthesia to monitor right coronary blood flow, cardiac output, central aortic blood pressure, and right ventribular pressure. In normotensive dogs, systolic flow amplitude equaled early diastolic flow levels. The ratio of systolic to diastolic flow at rest was substantially greater in the right coronary bed (36+/-1.3%) than in the left circumflex bed (13+/-3.6%). Right diastolid flow runoff, including the cove late in diastole, resembled left circumflex runoff. Blood flow to the normotensive right (37+/-1.1 ml/min 100(-1) g) and the left (35+/-1.0 ml/min(-1) g) ventricular myocardium indicated equal perfusion of both cardiac walls. Throttling of systolic flow was related directly to the right ventricular systolic pressure level in the dogs with pulmonic stenosis. Retrograde systolic flow occurred in severe right ventricular hypertension. The late diastolic runoff pattern in dogs with pulmonic stenosis appeared the same as for the normotensive dogs. We obtained systolic to diastolic flow ratios of 1/3 the value of normotensive hearts in high and severe pulmonic hypertension. Electrocardiograms and studies of pathology suggested restricted blood flow to the inner layers of the right myocardium in the dogs with severe and high right ventricular hypertension. Normotensive and hypertensive peak hyperemic flow responses were similar, except for an increased magnitude of diastolic flow, with proportionately less systolic flow in hypertensive states.  (+info)

Evaluation of the force-frequency relationship as a descriptor of the inotropic state of canine left ventricular myocardium. (2/1232)

The short-term force-frequency characteristics of canine left ventricular myocardium were examined in both isolated and intact preparations by briefly pertubing the frequency of contraction with early extrasystoles. The maximum rate of rise of isometric tension (Fmas) of the isolated trabeculae carneae was potentiated by the introduction of extrasystoles. The ratio of Fmas of potentiated to control beats (force-frequency ratio) was not altered significantly by a change in muscle length. However, exposure of the trabeculae to isoproterenol (10(-7)M) significantly changed the force-frequency ratio obtained in response to a constant frequency perturbation. Similar experiments were performed on chronically instrumented conscious dogs. Left ventricular minor axis diameter was measured with implanted pulse-transit ultrasonic dimension transducers, and intracavitary pressure was measured with a high fidelity micromanometer. Atrial pacing was performed so that the end-diastolic diameters of the beats preceding and following the extrasystole could be made identical. Large increases in the maximum rate of rise of pressure (Pmas) were seen in the contraction after the extrasystole. The ratio of Pmax of the potentiated beat to that of the control beat was not changed by a 9% increase in the end-diastolic diameter, produced by saline infusion. Conversely, isoproterenol significantly altered this relationship in the same manner as in the isolated muscle. Thus, either in vitro or in situ, left ventricular myocardium exhibits large functional changes in response to brief perturbations in rate. The isoproterenol and length data indicate that the force-frequency ratio reflects frequency-dependent changes in the inotropic state, independent of changes in length.  (+info)

Investigation of the theory and mechanism of the origin of the second heart sound. (3/1232)

To investigate further the origin of the second heart sound we studied human subjects, dogs, and a model in vitro of the cardiovascular system. Intra-arterial sound, pressure, and, where possible, flow and high speed cine (2,000 frames/sec) were utilized. The closure sound of the semilunar valves was of higher amplitude in be ventricles than in their respective arterial cavities. The direction of inscription of the main components of intra-arterial sound were opposite in direction to the components of intraventricular sound. Notches, representative of pressure increments, were noted on the ventricular pressure tracings and were coincident with the components of sound. The amplitude of the closure sound varied with diastolic pressure, but remained unchanged with augmentation of forward and retrograde aortic flow. Cines showed second sound to begin after complete valvular closure, and average leaflet closure rate was constant regardless of pressure. Hence, the semilunar valves, when closed, act as an elastic membrane and, when set into motion, generate compression and expansion of the blood, producing transient pressure changes indicative of sound. The magnitude of the initial stretch is related to the differential pressure between the arterial and ventricular chambers. Sound transients which follow the major components of the second sound appear to be caused by the continuing stretch and recoil of the leaflets. Clinically unexplained findings such as the reduced or absent second sound in calcific aortic stenosis and its paradoxical presence in congenital aortic stenosis may be explained by those observations.  (+info)

Filter-based coded-excitation system for high-speed ultrasonic imaging. (4/1232)

We have recently presented a new algorithm for high-speed parallel processing of ultrasound pulse-echo data for real-time three-dimensional (3-D) imaging. The approach utilizes a discretized linear model of the echo data received from the region of interest (ROI) using a conventional beam former. The transmitter array elements are fed with binary codes designed to produce distinct impulse responses from different directions in ROI. Image reconstruction in ROI is achieved with a regularized pseudoinverse operator derived from the linear receive signal model. The reconstruction operator can be implemented using a transversal filter bank with every filter in the bank designed to extract echoes from a specific direction in the ROI. The number of filters in the bank determines the number of image lines acquired simultaneously. In this paper, we present images of a cyst phantom reconstructed based on our formulation. A number of issues of practical significance in image reconstruction are addressed. Specifically, an augmented model is introduced to account for imperfect blocking of echoes from outside the ROI. We have also introduced a column-weighting algorithm for minimizing the number of filter coefficients. In addition, a detailed illustration of a full image reconstruction using subimage acquisition and compounding is given. Experimental results have shown that the new approach is valid for phased-array pulse-echo imaging of speckle-generating phantoms typically used in characterizing medical imaging systems. Such coded-excitation-based image reconstruction from speckle-generating phantoms, to the best of our knowledge, have not been reported previously.  (+info)

Use of high-intensity focused ultrasound to control bleeding. (5/1232)

OBJECTIVE: High-intensity focused ultrasound (HIFU) has been shown to be effective in controlling hemorrhage from punctures in blood vessels. The objective of the current study was to investigate the capability of HIFU to stop bleeding after a more severe type of vascular injury, namely longitudinal incisions of arteries and veins. METHODS: The superficial femoral arteries, common femoral arteries, carotid arteries, and jugular veins of four anesthetized pigs were exposed surgically. A longitudinal incision, 2 to 8 mm in length, was produced in the vessel. HIFU treatment was applied within 5 seconds of the onset of the bleeding. The HIFU probe consisted of a high-power, 3.5-MHz, piezoelectric transducer with an ellipsoidal focal spot that was 1 mm in cross section and 9 mm in axial dimension. The entire incision area was scanned with the HIFU beam at a rate of 15 to 25 times/second and a linear displacement of 5 to 10 mm. A total of 76 incisions and HIFU treatments were performed. RESULTS: Control of bleeding (major hemosatsis) was achieved in all 76 treatments, with complete hemostasis achieved in 69 treatments (91%). The average treatment times of major and complete hemostasis were 17 and 25 seconds, respectively. After the treatment, 74% of the vessels in which complete hemostasis was achieved were patent with distal blood flow and 26% were occluded. The HIFU-treated vessels showed a consistent coagulation of the adventitia surrounding the vessels, with a remarkably localized injury to the vessel wall. Extensive fibrin deposition at the treatment site was observed. CONCLUSION: HIFU may provide a useful method of achieving hemostasis for arteries and veins in a variety of clinical applications.  (+info)

Laparoscopy-assisted intrapelvic sonography with a high-frequency, real-time miniature transducer for assessment of the Fallopian tube: a preliminary report. (6/1232)

Our purpose was to visualize normal and abnormal Fallopian tubes using laparoscopy-assisted intrapelvic sonography with a specially developed 20 MHz flexible catheter-based high-resolution, real-time miniature (2.4 mm outer diameter) ultrasound transducer in infertile women. A total of 21 women (20 infertile, one with unilateral hydrosalpinx, and one tubal pregnancy) were studied with pelvic saline effusion under laparoscopy. Fimbriae were clearly depicted with a cockscomb-like form in 95% of patients. All ampullae were visualized, and mucosal layers were clearly distinguished from muscle layers in 70% of patients. Scanty intratubal effusion was noted in 50% of patients, and tubal spastic findings were found in 10% of patients. In all, 60% of isthmuses were detected, and mucosal layers were distinguished from muscle layers in 30%. In the subject with hydrosalpinx, the tubal wall was thinner, and it was not possible to distinguish between muscle and mucosal layers. In the subject with a tubal pregnancy, the amniotic membrane and decidua were depicted more clearly than by transvaginal sonography. In conclusion, laparoscopy-assisted intrapelvic sonography with a high-frequency, real-time miniature transducer may be useful in the assessment of tubal texture and function in tubal disorders, possibly in infertility practice.  (+info)

Metabolic cost of generating horizontal forces during human running. (7/1232)

Previous studies have suggested that generating vertical force on the ground to support body weight (BWt) is the major determinant of the metabolic cost of running. Because horizontal forces exerted on the ground are often an order of magnitude smaller than vertical forces, some have reasoned that they have negligible cost. Using applied horizontal forces (AHF; negative is impeding, positive is aiding) equal to -6, -3, 0, +3, +6, +9, +12, and +15% of BWt, we estimated the cost of generating horizontal forces while subjects were running at 3.3 m/s. We measured rates of oxygen consumption (VO2) for eight subjects. We then used a force-measuring treadmill to measure ground reaction forces from another eight subjects. With an AHF of -6% BWt, VO2 increased 30% compared with normal running, presumably because of the extra work involved. With an AHF of +15% BWt, the subjects exerted approximately 70% less propulsive impulse and exhibited a 33% reduction in VO2. Our data suggest that generating horizontal propulsive forces constitutes more than one-third of the total metabolic cost of normal running.  (+info)

Lumbar intradiscal pressure after posterolateral fusion and pedicle screw fixation. (8/1232)

In vitro biomechanical testing was performed in single-functional spinal units of fresh calf lumbar spines, using pressure needle transducers to investigate the effect of posterolateral fusion (PLF) and pedicle screw constructs (PS) on intradiscal pressure (IDP), in order to elucidate the mechanical factors concerned with residual low back pain after PLF. IDP of 6 calf lumbar spines consisting of L4 and L5 vertebrae and an intervening disc was measured under axial compression, flexion-extension and lateral bending in the intact spine, PS, PLF and the destabilized spine. Relative to the intact spines, the destabilized spines showed increased IDP in all of lordings and moments. IDP under PS and PLF were significantly decreased in axial compression, extension and lateral bending loads (p<0.05). In flexion, IDP under PS and PLF increased linearly proportional to the magnitude of flexion moment and reached as high as IDP of the intact spines. These results demonstrated that despite an increase in the stiffness of motion segments after PLF and PS, significant high disc pressure is still generated in flexion. Flexibility of PS and PLF may cause increased axial load sharing of the disc in flexion and increased IDP. This high IDP may explain patients' persisting pain following PS and PLF.  (+info)

In the last two decades, capacitive micromachined ultrasonic transducers (CMUTs) have proven themselves to be promising for various ultrasound imaging and chemical sensing applications. Although holding many benefits for ultrasound imaging, CMUTs have certain weaknesses such as the relatively low output pressure at transmission, which hinder their development in the diagnostic imaging application. In the sensing area, CMUTs have shown attractive features such as high mass sensitivity, miniaturized array configuration, and ease of functionalization. However, their potential for humidity sensing is less explored. The objectives of this thesis lie in two aspects. One is to offer a solution to overcome the limitation of low output pressure, and the other is to develop CMUTs as resonant gravimetric humidity sensors. The major efforts are made on the second task. For the first objective, a novel dual-element ultrasonic transducer is proposed. It incorporates two transducer technologies by using a ...
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Photoacoustic imaging combines the contrast advantage of pure optical imaging and the resolution advantage of pure ultrasonic imaging. It has become a popular research subject at present. A fast photoacoustic imaging system based on multi-element linear transducer array and phase-controlled focus method was developed and tested on phantoms and tissues. A Q switched Nd:YAG laser operating at 532nm was used in our experiment as thermal source. The multi-element linear transducer array consists of 320 elements. By phase-controlled focus method, 64 signals, one of which gathered by 11-group element, make up of an image. Experiment results can map the distribution of the optical absorption correctly. The same transducer array also can operate as a conventional phase array and produced ultrasound imaging. Compared to other existing technology and algorithm, the PA imaging based on transducer array was characterize by speediness and convenience. It can provide a new approach for tissue functional ...
In this thesis a design of a CMOS transimpedance amplifier (TIA) for a capacitive micro-machined ultrasonic transducer (CMUT) is presented. CMUTs have a high electrical impedance when used as receivers. Any capacitance between the CMUT and a high impedance amplifier will degrade the frequency response. So, we need to amplify the current rather than the voltage. This approach requires a transimpedance amplifier. The designed TIA has a 30 MHz bandwidth and 400 kΩ transimpedance gain. The total input referred current noise of the TIA is 270 fA/√Hz at 10 MHz. The noise figure of the TIA is 2.7 dB at 10 MHz when connected to the CMUT with 200 kΩ source resistance. The power consumption of the TIA is 10.5 mW and the size of the TIA layout is 133µm x 45µm. The TIA chip will be fabricated in AMS C35B4C3 (0.35µm) process ...
A miniature piezoelectric transducer element is provided, comprising: (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter. When used as a transmitter, the electrodes are electrically connected to an electrical circuit including a switching element for modulating the reflected
According to the present invention, there is provided an ultrasound therapy system comprising: an annular array ultrasound transducer having a plurality of ring transducer elements arranged concentrically, for transmitting an ultrasound beam in response to drive signals applied thereto, and for outputting echo signals in response to an ultrasound beam as received; transmitting/receiving means for generating and supplying drive signals to said transducer elements to cause said ultrasound transducer to transmit an ultrasound beam for imaging and an ultrasound beam for treatment, and for processing echo signals from said transducer elements corresponding to the received ultrasound beam; and beam pattern control means, provided in said transmitting/ receiving means, comprising means for delaying at least one of the drive signals for driving said transducer elements and the echo signals output from said transducer elements in accordance with a selected one of predetermined delay patterns, thereby ...
An improved method for fabrication of a multiple-element piezoelectric transducer and the transducer produced thereby. A green precursor tape is produced by doctor-blade tape-casting of a slurry containing lead zirconate-titanate (PZT) powder. After drying, individual strips of the tape are stacked between flat plates of previously sintered PZT, and sintered to form PZT strips; Pb from the previously sintered PZT plates makes up any Pb lost from the surfaces of the tape strips during sintering. The PZT strips are stacked interposed by layers of a thermoplastic polymer, and heated to a temperature above the melting point of the polymer, forming a laminate block. This block is then sliced perpendicular to the plane of the layers, forming slabs of alternate PZT and polymer layers; the slabs are then sliced perpendicular to the first slicing planes, forming strips of alternating PZT and polymer material. Electrodes are then added to complete the transducer assembly.
1D model of piezoelectric transducers based on a piezoelectric element vibrating in thickness mode with a backing block and a stack of impedance matching layers on the radiating surface . The model calculates the electrical impedance, the electrical response when a plane wave impignes on the transducer surface and the surface displacement when the transducer…
Frequency characteristics of ultrasound detectors used in optoacoustic tomography have a major impact on imaging performance. It is common practice to select transducers based on their sensitivity at the central frequency and under normal incidence. However, the bandwidth and angular sensitivity play an equally important role in establishing the quality and accuracy of the reconstructed images. Here, we developed a calibrated optoacoustic characterization method specifically tailored for broadband measurements of the angular transducer sensitivity (directivity). Ultrawideband omnidirectional optoacoustic responses were generated by uniformly illuminating thin absorbing sutures with nanosecond laser pulses and characterized with a needle hydrophone. This calibrated optoacoustic source was used to characterize the frequency dependence of the angular response by a conventional piezoelectric transducer (PZT) and a capacitive micromachined ultrasonic transducer (cMUT) with similar size and central ...
TY - JOUR. T1 - Advances in energy harvesting using low profile piezoelectric transducers. AU - Priya, Shashank. N1 - Funding Information: Acknowledgement The author is grateful for the support from Texas ARP grant 003656-0010-2006.. PY - 2007/9. Y1 - 2007/9. N2 - The vast reduction in the size and power consumption of sensors and CMOS circuitry has led to a focused research effort on the on-board power sources which can replace the batteries. The concern with batteries has been that they must always be charged before use. Similarly, the sensors and data acquisition components in distributed networks require centralized energy sources for their operation. In some applications such as sensors for structural health monitoring in remote locations, geographically inaccessible temperature or humidity sensors, the battery charging or replacement operations can be tedious and expensive. Logically, the emphasis in such cases has been on developing the on-site generators that can transform any available ...
2. The ultrasound diagnostic apparatus according to claim 1, comprising:the cap whose outer periphery contacts the cavity wall directly or via the medium outside the cap;the ultrasound transducer including the electromechanical transducer element and the lens in a concave shape provided on the electromechanical transducer element, rotatable or swingable around a center axis of the cap, capable of transmitting ultrasound with the electromechanical transducer element as the sound source and/or receiving echo from the subject area via the cap, and provided in the cap; andan acoustic medium which is filled between an inner surface of the cap and the ultrasound transducer in the cap, and a sound velocity in the acoustic medium is lower than that in the medium outside the cap,whereinthe acoustic lens focuses the ultrasound transmitted from the electromechanical transducer element, and includes a shape in which a first focal length of a first lens surface on a section parallel with the ultrasound ...
A string instrument pickup system sensitive to 360 of transverse string movement, which is substantially immune from microphonics, and which has a substantially equal or balanced response to all of the strings. In one form of the invention a piezoelectric transducer is compressively associated with vertical movement components of each string of the instrument, but is laterally offset from a centered position under the string for compressive association of the transducer also with the horizontal string movement components; and halves of the total piezoelectric transducer area are oppositely polarized so as to cancel out microphonics. In a modular form of the invention a plurality of the piezoelectric transducers are supported in an elongated array by means of a flexible body of electrically insulative material and a pliable outer wrapping of metal foil so that the transducer is conformable to distortions and deformations in string saddle and bridge elements of the instrument between which the modular
TY - JOUR. T1 - CMUT Electrode Resistance Design: Modelling and Experimental Verification by a Row-Column Array. AU - Havreland, Andreas Spandet. AU - Engholm, Mathias. AU - Tomov, Borislav Gueorguiev. AU - Jensen, Jørgen Arendt. AU - Hansen, Ole. AU - Thomsen, Erik Vilain. PY - 2019. Y1 - 2019. N2 - This paper addresses the importance of having control over the resistivity of the electrodes for capacitive micromachined ultrasonic transducers (CMUT) devices. The electrode resistivity can vary depending on the fabrication technology used, and resistivity control becomes especially important in the cases where metal electrodes can not be used. This raises the question: When is the resistivity of an electrode sufficiently low? To answer this question we have developed a simple design criterion. The criterion describes the attenuation of AC signals along a CMUT element. It is shown that the non-dimensional product between angular excitation frequency, resistance, and capacitance ωRC of an element ...
Stanford University Oral Defense - Department of Electrical Engineering Speaker: Amin Nikoozadeh Title: Intracardiac Ultrasound Imaging Using Capacitive Micromachined Ultrasonic Transducer (CMUT) Arrays Advisor: Professor B. T. Khuri-Yakub Date: Friday, June 04, 2010 Time: 09:30 AM (Refreshments at 9:15 AM) Location: Clark Center Auditorium (Basement, entrance across from Nexus) Map: http://ucomm.stanford.edu/map/?q=Clark%20Center ,http://ucomm.stanford.edu/map/?q=Clark%20Center&sf=a.BLDG_NAME, &sf=a.BLDG_NAME ABSTRACT Atrial fibrillation, the most common type of cardiac arrhythmia, now affects more than 2.2 million adults in the US alone. Currently, electrophysiological interventions are performed under fluoroscopic guidance, which does not provide adequate soft-tissue resolution and exposes the patient and the operator to harmful ionizing radiation. Intracardiac echocardiography (ICE) provides real-time anatomical information that has proven valuable in reducing the fluoroscopy time and ...
Piezoelectric ultrasonic transducers are available in a wide range of shapes like disks, plates or tubes, and different performance levels.
This press release contains forward-looking statements within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, projections about our business and our future revenues, expenses and profitability. Forward-looking statements may be, but are not necessarily, identified by the use of forward-looking terminology such as may, anticipates, estimates, expects, intends, plans, believes, and words and terms of similar substance. Forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause the actual events, results, performance, circumstances or achievements of the Company to be materially different from any future events, results, performance, circumstances or achievements expressed or implied by such forward-looking statements. Such forward-looking statements include statements relating to the Company exploring strategic ...
Forward-Looking Statements The information in this press release contains forward-looking statements and information within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the safe harbor created by those sections. These forward-looking statements include, but are not limited to, statements concerning the anticipated launch of DecisionDx-SCC. The words anticipates, believes, estimates, expects, intends, may, plans, projects, will, would and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. We may not actually achieve the plans, intentions, or expectations disclosed in our forward-looking statements and you should not place undue reliance on our forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations ...
Cautionary Statement on Forward-looking Information. Certain statements in this press release that are forward-looking and not statements of historical fact are forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are forward-looking information within the meaning of Canadian securities laws (collectively forward-looking statements). The company cautions that such statements involve risks and uncertainties that may materially affect the companys results of operations. Such forward-looking statements are based on the beliefs of management as well as assumptions made by and information currently available to management. Actual results could differ materially from those contemplated by the forward-looking statements as a result of certain factors, including but not limited to the ability to establish that potential products are efficacious or safe in preclinical or clinical trials; the ability to establish or ...
This release may contain forward-looking statements. Forward-looking statements are all statements other than statements of historical fact. Statements contained in this release that are not historical facts may be deemed to be forward-looking statements. The words anticipate, may, can, plans, believes, estimates, expects, projects, targets, intends, likely, will, should, to be, potential and any similar expressions are intended to identify those assertions as forward-looking statements.. Investors are cautioned that forward-looking statements are inherently uncertain. Actual performance and results may differ materially from that projected or suggested herein due to certain risks and uncertainties. In evaluating forward-looking statements, you should consider the various factors which may cause actual results to differ materially from any forward-looking statements including those listed in the Risk Factors section of our latest 10-K report. Further, the Company ...
This press release includes forward-looking statements and forward-looking information within the meaning of United States securities laws, including statements regarding CytoDyns current and proposed trials and studies and their results, costs and completion. These statements and information represent CytoDyns intentions, plans, expectations, and beliefs and are subject to risks, uncertainties and other factors, many beyond CytoDyns control. These factors could cause actual results to differ materially from such forward-looking statements or information. The words believe, estimate, expect, intend, attempt, anticipate, foresee, plan, and similar expressions and variations thereof identify certain of such forward-looking statements or forward-looking information, which speak only as of the date on which they are made.. CytoDyn disclaims any intention or obligation to publicly update or revise any forward-looking statements or forward-looking information, whether as a result of ...
Certain statements in this website may constitute forward-looking statements as defined in Section 27A of the Securities Act of 1933, as amended (the Securities Act), Section 21E of the Securities Exchange Act of 1934 (the Exchange Act), the Private Securities Litigation Reform Act of 1995 (the PSLRA) or in releases made by the Securities and Exchange Commission (SEC), all as may be amended from time to time. Such forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause the actual results, performance or achievements of GBS, Inc. and its affiliates (GBS) or industry results, to differ materially from any future results, performance or achievements expressed or implied by such forward-looking statements. Statements that are not historical fact are forward-looking statements. Forward-looking statements can be identified by, among other things, the use of forward-looking language, such as the words plan, believe, ...
This site may contain statements, estimates or projections that constitute forward-looking statements as defined under U.S. federal securities laws. These forward-looking statements generally can be identified by the context of the statement or the use of forward-looking terminology, such as believes, estimates, anticipates, intends, expects, plans, is confident that or words of similar meaning. Similarly, statements that describe AECOMs future operating performance, financial results, financial position, plans, objectives, strategies or goals are forward-looking statements. These forward-looking statements are based on AECOMs current expectations. Known and unknown internal and external risks and uncertainties may cause the actual results to be materially different from those expressed in or implied by the forward-looking statements. Such risks and uncertainties include, but are not limited to, the risk factors noted in AECOMs filings with the Securities and Exchange ...
This news release contains forward-looking statements, which are based on managements expectations and are subject to uncertainties and changes in circumstances. Words and expressions reflecting something other than historical fact are intended to identify forward-looking statements, and these statements may include terminology such as may, will, should, expect, plan, anticipate, believe, estimate, future, predict, potential, intend, or continue, and similar expressions. We base our forward-looking statements on our current expectations and projections about future events or future financial performance. Our forward-looking statements are subject to known and unknown risks, uncertainties and assumptions about ETC and its subsidiaries that may cause actual results to be materially different from any future results implied by these forward-looking statements. We caution you not to place undue reliance on these forward-looking statements. ...
This news release contains forward-looking statements, which are based on managements expectations and are subject to uncertainties and changes in circumstances. Words and expressions reflecting something other than historical fact are intended to identify forward-looking statements, and these statements may include terminology such as may, will, should, expect, plan, anticipate, believe, estimate, future, predict, potential, intend, or continue, and similar expressions. We base our forward-looking statements on our current expectations and projections about future events or future financial performance. Our forward-looking statements are subject to known and unknown risks, uncertainties and assumptions about ETC and its subsidiaries that may cause actual results to be materially different from any future results implied by these forward-looking statements. We caution you not to place undue reliance on these forward-looking statements. ...
Sanofi Forward-Looking Statements. This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words expects, anticipates, believes, intends, estimates, plans and similar expressions. Although Sanofis management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond ...
These statements constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words anticipate, believe, estimate, expect, intend, may, plan, predict, project, target, potential, will, would, could, should, possible, continue and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release, and we undertake no obligation to update any forward-looking statement except as required by law. These forward-looking statements are based on estimates and assumptions by our management that, although believed to be reasonable, are inherently uncertain and subject to a number of risks. The following represent some, but not ...
President & CEO. This news release contains forward-looking information within the meaning of applicable Canadian securities legislation. Generally, forward-looking information can be identified by the use of forward-looking terminology such as anticipate, believe, plan, expect, intend, estimate, forecast, project, budget, schedule, may, will, could, might, should or variations of such words or similar words or expressions. Forward-looking information is based on reasonable assumptions that have been made by Mission Ready Services Inc. as at the date of such information and is subject to known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, performance or achievements of Mission Ready Services Inc. to be materially different from those expressed or implied by such forward-looking information.. Forward-looking statements are based on assumptions management believes to be reasonable. Although Mission Ready ...
Email: [email protected] CAUTIONARY STATEMENT ON FORWARD-LOOKING INFORMATION. Certain information contained or incorporated by reference in this Fourth Quarter and Year-End Report 2014, including any information as to our strategy, projects, plans or future financial or operating performance, constitutes forward-looking statements. All statements, other than statements of historical fact, are forward-looking statements. The words believe, expect, anticipate, contemplate, target, plan, intend, continue, budget, estimate, may, will, schedule and similar expressions identify forward-looking statements. Forward-looking statements are necessarily based upon a number of estimates and assumptions that, while considered reasonable by the company, are inherently subject to significant business, economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forward-looking ...
If one or more of the factors affecting the Companys forward-looking information and statements renders forward-looking information or statements incorrect, the Companys actual results, performance or achievements could differ materially from those expressed in, or implied by, the forward-looking information and statements. Therefore, the Company cautions the reader not to place undue reliance on any forward-looking information or statements herein. The effect of these factors is difficult to predict. Factors other than these also could adversely affect the Companys results, and the reader should not consider these factors to be a complete set of all potential risks or uncertainties as new factors emerge from time to time. Management cannot assess the impact of any such factor on the Companys business or the extent to which any factor, or combination of factors, may cause results to differ materially from those contained in any forward-looking statement. Any forward-looking statements only ...
For more information, please visit www.x4pharma.com. Forward-Looking Statements. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. The words may, will, could, would, should, expect, plan, anticipate, intend, believe, estimate, predict, project, potential, continue, target and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Forward-looking statements include, but are not limited to, statements regarding X4s business strategy, including its clinical development plans. These statements are subject to various risks and uncertainties, actual results could differ materially from those projected, and X4 cautions investors not to place undue reliance on the forward-looking statements in this press release. These risks and uncertainties include, without limitation, the risk that ...
medicines and help patients recover stronger and live longer. Words such as to be, will, commitment, potential, plan, mission, or other similar expressions identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward-looking. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements are based upon Exelixis current plans, assumptions, beliefs, expectations, estimates and projections. Forward-looking statements involve risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of these risks and uncertainties, which include, without limitation: risks and uncertainties related to regulatory review and approval processes and Exelixis compliance with applicable legal and regulatory ...
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates regarding the clinical development of and potential marketing approvals for the product. Forward-looking statements are generally identified by the words expects, anticipates, believes, intends, estimates, plans, would be and similar expressions. Although Sanofis management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements, other than statements of historical fact, including statements regarding our plans and prospects regarding ZIKV-VLA1601, and any other statements containing the words believes, expects, anticipates, intends, plans, estimates and similar expressions, are forward-looking statements. These forward-looking statements are based on our current intentions, beliefs and expectations regarding future events. We cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from our expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement. Any forward-looking statement speaks only as of the date of this press release, and, except as ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements, other than statements of historical fact, including statements regarding our plans and prospects regarding ZIKV-VLA1601, and any other statements containing the words believes, expects, anticipates, intends, plans, estimates and similar expressions, are forward-looking statements. These forward-looking statements are based on our current intentions, beliefs and expectations regarding future events. We cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from our expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement. Any forward-looking statement speaks only as of the date of this press release, and, except as ...
IMPORTANT INFORMATION REGARDING FORWARD-LOOKING STATEMENTS. Certain information set out in this news release constitutes forward-looking information. Forward-looking statements are often, but not always, identified by the use of words such as seek, anticipate, plan, continue, estimate, expect, may, will, intend, could, might, should, believe, schedule and similar expressions. Forward-looking statements are based upon the opinions and expectations of management of the Company as at the effective date of such statements and, in certain cases, information received from or disseminated by third parties. Although the Company believes that the expectations reflected in such forward-looking statements are based upon reasonable assumptions and that information received from or disseminated by third parties is reliable, it can give no assurance that those expectations will prove to have been correct. Forward-looking statements are subject to certain risks and uncertainties ...
A semi-invasive ultrasound imaging system for imaging biological tissue includes a transesophageal probe or a transnasal, transesophageal probe connected to a two-dimensional ultrasound transducer array, a transmit beamformer, a receive beamformer, and an image generator. The two-dimensional transducer array is disposed on a distal portion of the probes elongated body. The transmit beamformer is connected to the transducer array and is constructed to transmit several ultrasound beams over a selected pattern defined by azimuthal and elevation orientations. The receive beamformer is connected to the transducer array and is constructed to acquire ultrasound data from the echoes reflected over a selected tissue volume. The tissue volume is defined by the azimuthal and elevation orientations and a selected scan range. The receive beamformer is constructed to synthesize image data from the acquired ultrasound data. The image generator is constructed to receive the image data and generate images that
This hand held vibration instrument for gum massage and removal of tartar formation is based on the piezo-electric effect. It comprises a high frequency oscillator which drives a set of piezo-electric wafers acting as transducers. The high frequency oscillator (18) which derives its power from the low voltage secondary of a mains transformer, drives a set of piezoelectric wafers (9,10) attached to the metallic vibrator (3). This extends via a vibration transformer (6), which transforms short sharp amplitudes into greater more gentle vibrations, to a rod (7), at the end of which is a bulb shaped tool (26). A central channel (22) is provided for a cleansing fluid.
Press Release issued Feb 13, 2017: Market Research Hub (MRH) has recently announced the inclusion of a new study to its market intelligence database, which is entitled as Label-free Array Systems Market- Global Industry Analysis 2016-2024. The report analyzes the global market with an in-depth investigation of some of the major regions including North America, Asia-Pacific, Latin America, Europe and Middle East & Africa. Moreover, this report studies the current scenario as well as the future market potential for label-free array systems globally.
This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements may be identified by words like anticipate, expect, project, believe, plan, estimate, intend and similar words. These forward-looking statements are based on our beliefs, assumptions and estimates using information available to us at the time and are not intended to be guarantees of future events or performance. These forward-looking statements include, among other things, statements regarding our business plans, clinical trials and the importance of their results, product performance and competitive offerings. If our underlying assumptions turn out to be incorrect, or if certain risks or uncertainties materialize, actual results could vary materially from the expectations and projections expressed or implied by our forward-looking statements. These factors, in some cases, have ...
This press release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 21E of the Securities Exchange Act of 1934, as amended. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, financial position, future revenues, projected costs, prospects, plans and objectives of management are forward-looking statements. Such forward-looking statements involve a number of risks and uncertainties and investors are cautioned not to put any undue reliance on any forward-looking statement. There are a number of important factors that could cause Cytogen s results to differ materially from those indicated by such forward-looking statements. In particular, Cytogen s business is subject to a number of significant risks, which include, but are not limited to Cytogen s ability to successfully execute strategic transactions for its technology platforms, as ...
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words expects, anticipates, believes, intends, estimates, plans and similar expressions. Although Sanofis management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could ...
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by phrases such as, Ecology Coatings (the Company), by and through its management, anticipates, believes, estimates, expects, forecasts, foresees, intends, plans, or other words of similar import. Similarly, statements herein that describe the Companys business strategy, outlook, objectives, plans, intentions or goals also are forward-looking statements. Such forward-looking statements involve known and unknown risks, uncertainties and a wide variety of other factors which may cause the actual results, performance or achievements of the Company to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Such factors include, but are not limited to, the Companys ability to: successfully commercialize its ...
The radiation pattern of shaded single element piezoelectric transducers and transducer arrays has reduced side lobe levels. Shading to reduce the intensity of emitted ultrasound at the edges of the transducer relative to the center is realized by varying the electric/acoustic conversion efficiency or polarization of the piezoelectric material, by having different mechanical element lengths, by selectively poling the piezoelectric material to produce poled and unpoled regions, and by control of electrode geometry. The shading of a phased array ultrasonic transducer is described in both lateral dimensions.
Pressure transducers are transducers that convers pressure into an analog electrical signal. Pressure transducers are devices used to control pressure systems as for instance in air pressure installation. Besides, pressure transducers can be also used to control pressure in boilers and direct them by means of a control system. Pressure transducers can be connected to any control system due to their ability to emit a standard signal so customers can use pressure transducers for many different applications.
The reproduction number R and the growth rate r are critical epidemiological quantities. They are linked by generation intervals, the time between infection and onward transmission. Because generation intervals are difficult to observe, epidemiologists often substitute serial intervals, the time between symptom onset in successive links in a transmission chain. Recent studies suggest that such substitution biases estimates of R based on r. Here we explore how these intervals vary over the course of an epidemic, and the implications for R estimation. Forward-looking serial intervals, measuring time forward from symptom onset of an infector, correctly describe the renewal process of symptomatic cases and therefore reliably link R with r. In contrast, backward-looking intervals, which measure time backward, and intrinsic intervals, which neglect population-level dynamics, give incorrect R estimates. Forward-looking intervals are affected both by epidemic dynamics and by censoring, changing in ...
Certain information on this Site contains certain forward-looking statements, which are subject to risks and uncertainties and speak only as of the date on which they are made. The words believe, estimate, expect, target, intend, may, plan or similar expressions are intended to identify forward-looking statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date on which they are made. GWG Holdings undertakes no obligation to update publicly or revise any forward-looking statements. Actual results may differ materially from the expectations disclosed in the forward-looking statements made. Important factors that could cause actual results to differ materially from the companys forward-looking statements are described in GWG Holdings periodic reports, including the Annual Report on Form 10-K, quarterly reports on Form 10-Q and other reports filed with the Securities and Exchange Commission. Please click here to ...
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. Therapeutic Ultrasound Devices Market is expected to witness growth of international market with respect to advancements and innovations including development history, competitive analysis and regional development forecast.. The report starts with a basic Therapeutic Ultrasound Devices market overview. In this introductory section, the research report incorporates analysis of definitions, classifications, applications and industry chain structure. Besides this, the report also consists of development trends, competitive landscape analysis, and key regions development status.. Browse Detailed TOC, Tables, Figures, Charts and Companies Mentioned in Therapeutic Ultrasound Devices Market Research [email protected] https://www.360marketupdates.com/europe-therapeutic-ultrasound-devices-market-report-2017-10462799. Therapeutic Ultrasound Devices Market Key Players Analysis:. ...
Experience the amazing image quality delivered by the Vevo MD high frequency ultrasound system. View clinical ultrasound image examples.
This communication contains forward-looking statements within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In this context, forward-looking statements often address expected future business and financial performance and financial condition, and often contain words such as expect, anticipate, intend, plan, believe, seek, see, will, would, target, similar expressions, and variations or negatives of these words. Forward-looking statements by their nature address matters that are, to different degrees, uncertain, such as statements about the consummation of the proposed transaction and the anticipated benefits thereof. Forward-looking statements are not guarantees of future performance and are based on certain assumptions and expectations of future events which may not be realized. Forward-looking statements also involve risks and uncertainties, ...
In some cases, forward-looking statements can be identified by terminology such as will, may, should, could, expects, intends, plans, aims, anticipates, believes, estimates, predicts, potential, continue, or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Modernas control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others: the fact that there has never been a commercial product utilizing mRNA technology approved for use; the fact that the rapid response technology in use by ...
This press release contains forward-looking statements about ORIC as that term is defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, statements regarding ORICs development plans; the ability of ORIC-101 to overcome resistance in cancer models; plans underlying ORIC-101 clinical trials and development; plans to report interim data from the two ongoing clinical trials of ORIC-101; and the potential advantages of ORICs product candidates. Words such as believes, anticipates, plans, expects, intends, will, goal, potential and similar expressions are intended to identify forward-looking statements. The forward-looking statements contained herein are based upon ORICs current expectations and involve assumptions that may never materialize or may prove to be incorrect. ...
Air-coupled ultrasonic techniques are being increasingly used for material characterization, non-destructive evaluation of composite materials using guided waves as well as for distance measurements. Application of those techniques is mainly limited by the big losses of ultrasonic signals due to attenuation and mismatch of the acoustic impedances of ultrasonic transducers and air. One of the ways to solve this problem is by application of novel more efficient piezoelectric materials like lead magnesium niobate-lead titanate (PMN-PT) type crystals. The objective of this research was the development and investigation of low frequency (<50 kHz) wide band air-coupled ultrasonic transducers and arrays with an improved performance using PMN-32%PT crystals. Results of finite element modelling and experimental investigations of the developed transducers and arrays are presented. For improvement of the performance strip-like matching elements made of low acoustic impedance, materials such as polystyrene foams
Discover Vevo® MD, the worlds first Ultra High Frequency ultrasound system for clinical use. Vevo® MD delivers the highest resolution possible in medical ultrasound when imaging the first 3cm of the body.
Cool new(er) technology might speed the time it takes to perform catheter ablation of atrial fibrillation: the high frequency ultrasound balloon. It has a fluid-filled inner chamber and an outer carbon dioxide-filled balloon that helps focus the ultrasound in a ring-like pattern in an attempt to ablate (or burn) around the pulmonary veins in the left atrium (the site where its thought the atrial fibrillation comes from). Average lesion time takes 40-90 seconds and it covers LOTS of territory in the left atrium. Its just starting clinical trials.... Seems promising. Well see ...
High Frequency Ultrasound Coagulating Cutter Market Research is expecting to accrue strong growth in forecasts frame, drive By Type, End User.
You are at: Home » Products » Disabilities » Ozone High Frequency Ultrasound / Ultrasonic Facia In total 213268 number ofProductsinfo,Released today. 0 number of ...
In this study, we will deploy annular-array systems and assess their experimental and clinical utility for ophthalmic imaging. We hypothesize that a 20-MHz annular array will detect posterior vitreous detachment (PVD) more reliably than a conventional single element ultrasound system. Clinically, we will test the hypothesis that 20-MHz annular arrays improve detection of PVD, an important risk factor for disease progression in diabetic retinopathy. Diabetic retinopathy is the leading cause of blindness in the working population (25 to 65 years) and the third major cause of legal blindness in the U.S.. We propose to carry out a study of 30 human subjects, aged 60 years or above, in whom PVD is likely to be present as a consequence of normal aging. The study will compare the ability to detect PVD using a commercial ophthalmic ultrasound system equipped with 10- and 20-MHz sector scan probes (Cinescan A/B-S, Quantel Medical), and OCT (OCT/SLO, Ophthalmic Technologies, Inc.), and the 20-MHz annular ...
0037] The present invention relates to an ultrasound coupling device suitable for use with low-profile ultrasound transducers and systems. The ultrasound coupling device of the present invention is particularly suitable for use with portable ultrasound devices, systems, and methods. Further, the ultrasound coupling device of the present invention can be configured to be either disposable or re-useable, and can be used with ultrasound transducers that are either disposable or re-usable. Therefore, in one aspect, the present invention provides an entirely autonomous ultrasound coupling device for use with portable ultrasound transducers and systems. In addition, the ultrasound coupling device of the present invention can be configured so as to enable the generation of ultrasonic energy from an ultrasound transducer or system. In this configuration, the ultrasound coupling device is configured so that ultrasonic energy is only transmitted when the ultrasound transducer is properly coupled with the ...
expected network coverage to new markets, expected expansion of 4G LTE bandwidth and the expected timing of closing the transaction, are forward-looking statements. Generally, forward-looking statements may be identified by words such as anticipate, expect, suggests, plan, believe, intend, estimates, targets, views, may, will, forecast, and other similar expressions. The forward-looking statements speak only as of the date made, are based on current assumptions and expectations, and involve a number of risks and uncertainties. Important factors that could affect future results and cause those results to differ materially from those expressed in the forward-looking statements include, among others, the following: adverse conditions in the U.S. and international economies and markets; our ability to successfully integrate the MetroPCS and ...
Item 2. Management s Discussion and Analysis of Financial Condition and Results of Operations The following discussion and analysis of our financial condition and results of operations should be read in conjunction with our condensed financial statements and related notes appearing elsewhere in this Quarterly Report on Form 10-Q and our annual report on Form 10-K dated December 31, 2014. Forward-Looking Statements This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act). These forward-looking statements are based on our management s belief and assumptions and on information currently available to management. Although we believe that the expectations reflected in these forward-looking statements are reasonable, these statements relate to future events, including our clinical development plans, or our future financial performance and involve ...
Statements in articles on this blog other than purely historical information, historical estimates should not be relied upon, including statements relating to the companies future plans and objectives or expected results, are forward-looking statements. News releases contain certain Forward-Looking Statements within the meaning of Section 21E of the United States Securities Exchange Act of 1934, as amended. Forward-looking statements are based on numerous assumptions and are subject to all of the risks and uncertainties inherent in the companies business, including risks inherent in resource exploration and development. As a result, actual results may vary materially from those described in the forward-looking statements ...
This release contains forward-looking statements regarding our strategy, future plans and prospects, including statements regarding the development of the companys product candidates, the potential safety and efficacy profile of roxadustat, the potential for our Phase 3 program data to form the basis of a regulatory approval, our clinical and regulatory plans, and those of our partners. These forward-looking statements include, but are not limited to, statements about our plans, objectives, representations and contentions and are not historical facts and typically are identified by use of terms such as may, will, should, on track, could, expect, plan, anticipate, believe, estimate, predict, potential, continue and similar words, although some forward-looking statements are expressed differently. Our actual results may differ materially from those indicated in these forward-looking statements due to risks and uncertainties related to the continued progress and timing of ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are subject to risks, uncertainties and other factors, including the risk that Genvoya may not be approved by other regulatory authorities and the marketing applications for F/TAF and/or R/F/TAF may not be approved by the EMA, and marketing approvals, if granted, may have significant limitations on their use. These risks, uncertainties and other factors could cause actual results to differ materially from those referred to in the forward-looking statements. The reader is cautioned not to rely on these forward-looking statements. These and other risks are described in detail in Gileads Quarterly Report on Form 10-Q for the quarter ended September 30, 2015, as filed with the U.S. Securities and Exchange Commission. All forward-looking statements are based on information currently available to Gilead, and Gilead assumes no obligation to update any such ...
This press release contains certain forward-looking statements that involve risks, uncertainties and assumptions that are difficult to predict, including statements regarding the Companys upcoming meeting with the FDA to discuss the adequate number and type of evaluable patients required for efficacy and safety necessary to support the filing of a Biologic License Application and our intention to continue enrolling patients in our CD02 combination trial. Words and expressions reflecting optimism, satisfaction or disappointment with current prospects, as well as words such as believes, hopes, intends, estimates, expects, projects, plans, anticipates and variations thereof, or the use of future tense, identify forward-looking statements, but their absence does not mean that a statement is not forward-looking. Our forward-looking statements are not guarantees of performance and actual results could differ materially from those contained in or expressed by such statements. In ...
For additional information, visit avrobio.com, and follow us on Twitter and LinkedIn. Forward-Looking Statement This press release contains forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words and phrases such as aims, anticipates, believes, could, designed to, estimates, expects, forecasts, goal, intends, may, plans, possible, potential, seeks, will, and variations of these words and phrases or similar expressions that are intended to identify forward-looking statements. These forward-looking statements include, without limitation, statements regarding our business strategy for and the potential therapeutic benefits of our prospective product candidates, the design, commencement, enrollment and timing of ongoing or planned clinical trials, clinical trial results, product approvals and regulatory pathways, anticipated ...
This release contains forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements are typically preceded by words such as believes, expects, anticipates, intends, will, may, should, or similar expressions. These forward-looking statements reflect managements current knowledge, assumptions, judgment and expectations regarding future performance or events. Although management believes that the expectations reflected in such statements are reasonable, they give no assurance that such expectations will prove to be correct or that those goals will be achieved, and you should be aware that actual results could differ materially from those contained in the forward-looking statements. Forward-looking statements are subject to a number of risks and uncertainties, including, but not limited to, our ability to successfully complete research and further development and commercialization of Company drug ...
is committed to improving the health of patients with kidney and vascular diseases through the development of novel, first-in-class therapeutics. Proteons lead product candidate, vonapanitase, is an investigational drug intended to improve hemodialysis vascular access outcomes. Proteon is currently enrolling patients in PATENCY-2, a Phase 3 clinical trial evaluating vonapanitase in patients with CKD undergoing surgical creation of a radiocephalic arteriovenous fistula for hemodialysis. Proteon is also evaluating vonapanitase in a Phase 1 clinical trial in patients with PAD. For more information, please visit www.proteontx.com.. Cautionary Note Regarding Forward-Looking Statements. This press release contains statements that are, or may be deemed to be, forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. In some cases, these forward-looking statements can be identified by the use of forward-looking terminology, including the terms estimates, ...
This press release includes forward-looking statements regarding the business of Akcea Therapeutics, Inc. and Ionis Pharmaceuticals, Inc. and the therapeutic and commercial potential of WAYLIVRATM (volanesorsen). Any statement describing Akceas or Ionis goals, expectations, financial or other projections, intentions or beliefs, including the commercial potential of WAYLIVRA or other of Akceas or Ionis drugs in development is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties, particularly those inherent in the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. Akceas and Ionis forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking ...
Forward-Looking Statements Certain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. Such forward-looking statements include statements about the advancement, therapeutic indication and use, safety, efficacy, tolerability, mechanism of action and potential of lorcaserin; the significance of the PWG s re-adjudication and the CSF study, including the potential use of the results; the response to the CRL for the lorcaserin NDA, including related plans, activities and timing; the therapeutic indication of APD811; and Arena s views, focus, goals, strategy, research and development programs, and ability to develop compounds and commercialize drugs. For such statements, Arena claims the protection of the Private Securities Litigation Reform Act of 1995. Actual events or results may differ materially from Arena s expectations. Factors that could cause actual results to differ materially from the forward-looking statements include, but are ...
We offer a variety of servo gearboxes and although they may appear the same, they function differently. Kyle goes through each style of gearbox and when they would be ideal for specific projects.. Channel Gearboxes: Designed to mount inside Actobotics Channel. Great for robotic arms and projects that have limited space. 1/2 output shaft.. Top Flange Gearboxes: Designed to be flush mounted with the tabs protruding from the top plane of the gearbox. Excellent for R/C sailboats. 3/8 output shaft.. Bottom Flange Gearboxes: Designed to be mounted to a flat surface with the bottom flanges. Great for FPV antenna trackers and base gearboxes on robotic arms. 3/8 output shaft.. Square Tube Gearboxes: Sleek, rectangular profile with mounting options on the ends and sides. 1/2 output shaft (1 shaft available on some models).. ...
Piezoelectric materials are utilized for high-power ultrasonic devices such as ultrasonic motors, which are driven under high stress and strain. The nonlinear elastic vibration of piezoelectric materials is a critical problem because it degrades the output performance. (Bi,Na)TiO3-BaTiO3 (BNBT) ceramics are one of the lead-free piezoelectric materials that show outstanding characteristics under high power driving, such as stable mechanical quality factor and resonance frequency. We evaluated the high-power characteristics of BNBT ceramics by measuring complex higher-order elastic constants using a nonlinear piezoelectric vibration model. We found that the absolute value of the higher-order elastic constant of BNBT was less than 4% of Pb(Zr,Ti)O3 (PZT). Additionally, we developed a miniature ultrasonic motor using a BNBT multilayered piezoelectric transducer. This multilayered structure was utilized to enhance the piezoelectric displacement and was equipped with elastic fins, which convert the ...
A device for acquiring data and diagnosing a musculoskeletal injury. The device includes a semi-flexible housing, at least one ultrasonic transducer, a positional localizer, and a transmission system. The semi-flexible housing is positioned proximate a portion of the musculoskeletal system of a patient and supports the at least one ultrasonic transducer and the positional localizer. The at least one ultrasonic transducer is configured to acquire an ultrasonic data indicative of a bone surface. The positional localizer is positioned at a select location relative to the at least one ultrasonic transducer and tracks movement of the housing. The transmission system transmits the ultrasonic data of the at least one ultrasonic transducer and the movement data of the positional localizer to a data analyzer for analysis and diagnosis.
At O-I Glass, Inc. (NYSE: OI), we love glass and were proud to make more of it than any other glass bottle or jar producer in the world. We love that its beautiful, pure and completely recyclable. With global headquarters in Perrysburg, Ohio, we are the preferred partner for many of the worlds leading food and beverage brands. Working hand and hand with our customers, we give our passion and expertise to make their bottles iconic and help build their brands around the world. With more than 26,500 people at 78 plants in 23 countries, O-I Glass has a global impact, achieving revenues of $6.9 billion in 2018. For more information, visit o-i.com.. Forward-Looking Statements. This press release contains forward-looking statements related to O-I Glass, Inc. (O-I Glass or the Company) within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act) and Section 27A of the Securities Act of 1933. These forward-looking statements relate to a variety of ...
This press release contains forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about ADMA Biologics, Inc. (we, our or the Company). Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate, or imply future results, performance or achievements, and may contain the words estimate, project, intend, forecast, target, anticipate, plan, planning, expect, believe, will, is likely, will likely, should, could, would, may, or, in each case, their negative, or words or expressions of similar meaning. These forward-looking statements also include, but are not limited to, statements concerning our plans to develop, manufacture, market, launch and expand our own commercial infrastructure and commercialize our current products and future products, the safety, efficacy and expected timing of, and our ability to, obtain and maintain regulatory ...
This press release contains forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about ADMA Biologics, Inc. (we, our or the Company). Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate, or imply future results, performance or achievements, and may contain the words estimate, project, intend, forecast, target, anticipate, plan, planning, expect, believe, will, is likely, will likely, should, could, would, may, or, in each case, their negative, or words or expressions of similar meaning. These forward-looking statements also include, but are not limited to, statements concerning our plans to develop, manufacture, market, launch and expand our own commercial infrastructure and commercialize our current products and future products, the safety, efficacy and expected timing of, and our ability to, obtain and maintain regulatory ...
First Majestic is a mining company focused on silver production in México and is aggressively pursuing the development of its existing mineral property assets and the pursuit through acquisition of additional mineral assets which contribute to the Company achieving its corporate growth objectives.. FIRST MAJESTIC SILVER CORP.. Keith Neumeyer, President & CEO Cautionary Note Regarding Forward-Looking Statements. This press release contains forward-looking statements, within the meaning of the United States Private Securities Litigation Reform Act of 1995 and applicable Canadian securities legislation, concerning the business, operations and financial performance and condition of First Majestic Silver Corp. Forward-looking statements include, but are not limited to, statements with respect to the future price of silver and other metals, the estimation of mineral reserves and resources, the realization of mineral reserve estimates, the timing and amount of estimated future production, costs of ...
Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping, and pre-clinical nucleic acid-based therapeutic drug candidates. Applied DNA makes life real and safe by providing innovative, molecular-based technology solutions and services that can help protect products, brands, entire supply chains, and intellectual property of companies, governments and consumers from theft, counterfeiting, fraud and diversion. Visit adnas.com for more information. Follow us on Twitter and LinkedIn. Join our mailing list. Common stock listed on NASDAQ under the symbol APDN, and warrants are listed under the symbol APDNW. Forward-Looking Statements The statements made by Applied DNA in this press release may be forward-looking in nature within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe Applied DNAs future plans, projections, strategies and expectations, and ...
This news release may contain certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. These statements are based on managements current expectations and are subject to uncertainty and changes in circumstances. Actual results may vary materially from the expectations contained in the forward-looking statements. The following factors, among others, could cause actual results to differ materially from those described in any forward-looking statements: competitive pressures; the loss of one or more key customer or supplier relationships; customer defaults or insolvencies; changes in customer mix; supplier defaults or insolvencies; changes in pharmaceutical manufacturers pricing and distribution policies or practices; adverse resolution of any contract or other disputes with customers (including departments and agencies of the U.S. Government) or suppliers; regulatory changes (including increased ...
This press release contains forward-looking statements, including statements that relate to, among other things, revenue forecasts, technology development progress, plans for shipment using the Companys technology, production plans, the Companys markets, objectives, goals, strategies, intentions, beliefs, expectations and estimates, and can generally be identified by the use of words such as may, will, could, should, would, likely, possible, expect, intend, estimate, anticipate, believe, plan, objective and continue (or the negative thereof) and words and expressions of similar import. Although the Company believes that the expectations reflected in such forward-looking statements are reasonable, such statements involve risks and uncertainties, and undue reliance should not be placed on such statements. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied ...
This news release contains forward-looking statements that are based upon current expectations or beliefs, as well as a number of assumptions about future events. Although we believe that the expectations reflected in the forward-looking statements and the assumptions upon which they are based are reasonable, we can give no assurance that such expectations and assumptions will prove to be correct. Forward-looking statements are generally identifiable by the use of words like may, will, should, could, expect, anticipate, estimate, believe, intend or project, or the negative of these words or other variations on these words or comparable terminology. To the extent that statements in this news release are not strictly historical, including, without limitation, statements as to our ability to improve the outcomes of cancer patients, the utility and effectiveness of our intellectual property protections, our ability to obtain additional patents in the future covering our ...
This press release contains certain forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans, objectives and future events. Theravance intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. Examples of such statements include statements relating to the status and timing of clinical studies, statements regarding the potential benefits and mechanisms of action of drug candidates, statements concerning the enabling capabilities of Theravances approach to drug discovery and its proprietary insights and statements concerning expectations for product candidates through development and commercialization. These statements are based on the current estimates and assumptions of the management of Theravance as ...
Anticipated effect is a targeted therapy envisioned to selectively destroy infectious agents or cancer cells with minimal negative effect on normal cells.. The Company cautions that COVID-19 therapeutic development is still under early-stage research and development and is not making any express or implied claims that it has the ability to treat, prevent or eliminate the COVID-19 virus at this time. The Companys scientific experts have read and approved the scientific disclosures contained in the press release.. About BriaCell. BriaCell is an immuno-oncology focused biotechnology company developing targeted and effective approaches for the management of cancer. For additional information on BriaCell, please visit: https://briacell.com/.. Cautionary Note Regarding Forward-Looking Information. Except for the statements of historical fact, this news release contains forward-looking information within the meaning of the applicable Canadian securities legislation (also known as forward-looking ...
Inductive transducers[edit]. A unique potential solution that can be exploited is the use of inductors as transducers. This ...
TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519. Farrens, S.; Sood, S. (2008). "Wafer Level ...
Micromachined ultrasound transducers. MEMS-based loudspeakers focusing on applications such as in-ear headphones and hearing ... TRANSDUCERS '05. 2. IEEE. pp. 1118-1121. doi:10.1109/SENSOR.2005.1497272. ISBN 9780780389946. S2CID 28068644. Bustillo JM, Howe ... Hajati A (2012). "Three-dimensional micro electromechanical system piezoelectric ultrasound transducer". Appl. Phys. Lett. 101 ...
TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519.CS1 maint: uses authors parameter (link) Sood, S ... This method works with an ultrasonic transducer scanning the wafer bond. The reflected sound signal is used for the image ... Deionized water is used as the acoustic interconnect medium between the electromagnetic acoustic transducer and the wafer. ...
TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519.CS1 maint: multiple names: authors list (link) ...
Piezoceramic transducers of physical sizes.- Cherkasy: ChGTU, 2005.- 631p. Sharapov V.M. et al. Automatic control theory. ... Piezoelectric transducers. The handbook. - Cherkasy: ChGTU, 2004. - 435 p. Sharapov V.M. et al. Programmed logic controllers in ... 240 p. ISBN 9781873082096 Sharapov V.М., Minaev I.G., Sotula Zh.V., Kunitskaya L.G. Electroacoustic Transducers. - Moscow: ... Sharapov V.M., Sotula Zh.V., Kunitskaya L.G. Piezoelectric electroacoustic transducers. - Cherkasy: Vertical, 2012.-255p. ...
Acoustic Transducers. United States: GedLee. ISBN 978-0972208505. Retrieved 2020-10-23. CS1 maint: discouraged parameter (link) ...
A loudspeaker (or loud-speaker or speaker) is an electroacoustic transducer;[1] which converts an electrical audio signal into ... Such transducers can cover a wide frequency range (80 Hz to 35,000 Hz) and have been promoted as being close to an ideal point ... Bending wave transducers use a diaphragm that is intentionally flexible. The rigidity of the material increases from the center ... Magnetostrictive transducers, based on magnetostriction, have been predominantly used as sonar ultrasonic sound wave radiators ...
The unit consists of a hollow tube that is sealed by a piezoelectric transducer on each end. The transducers are oppositely ... Finally the outputs of the individual transducers are measured, the residual voltage difference is tabulated, and the dominate ... Norton, Harry N.(1989). Handbook of Transducers. Prentice Hall PTR. ISBN 0-13-382599-X 'PDF Link' 'Piezoelectric Tranducers' ' ... Accelerometers based upon piezoelectricity are constructed with two piezoelectric transducers. ...
2011). "The Mechanical and Tribological Properties of Epoxy Nanocomposites with WS2 Nanotubes". Sensors & Transducers Journal. ...
Sinclair, I. (2000). Sensors and Transducers. Elsevier Science. p. 258. ISBN 978-0-08-051699-8. Retrieved 13 September 2018. v ...
To maximize efficiency, transducers are often placed in arrays: a grid of sometimes hundreds of transducers. This arrangement ... Transducers of this form also lend themselves to compensation against the hydrostatic pressures encountered in sonar, ... EP 0473480, "Electroacoustic transducer for use under water and comprising a system for automatically compensating the ... The term tonpilz or "acoustic mushroom" may refer to a certain type of underwater electro-acoustic transducer. By sandwiching ...
TRANSDUCERS & EUROSENSORS XXXIII): 523-526. doi:10.1109/TRANSDUCERS.2019.8808358. ISBN 978-1-5386-8104-6. S2CID 201620129. Ruby ... TRANSDUCERS & EUROSENSORS XXXIII): 450-453. doi:10.1109/TRANSDUCERS.2019.8808374. ISBN 978-1-5386-8104-6. S2CID 201621456. ... Dubois, M.-A.; Muralt, P. (1999). "Properties of aluminum nitride thin films for piezoelectric transducers and microwave filter ... was evaporated on a resonant piece of bulk quartz crystal which served as a transducer providing a Q factor (quality factor) of ...
He has been hailed as not just a pioneer of electroacoustics, but also as the "father of modern sonar transducer development," ... In the mid-1930s, the U.S. Navy began contracting with RCA-Victor for electroacoustic transducers that could meet stringent ... Throughout the war, Massa's team produced new acoustic transducers on an almost monthly basis for the Navy, with applications ... Massa, Frank (November 1989). "Sonar Transducers: A History". Sea Technology. Massa, Frank (April 1985). "Some personal ...
Early sonar transducers had been developed from simplistic design assumptions followed by a trial and error design modification ... NEL explored transducer theory with tensor analysis and continuum mechanics to determine viscous and hysteretic dissipative ... From 1954 to 1960 he led the NEL development team for a variable magnetic reluctance transducer intended for a low-frequency ... Martin, Gordon E. (1964). "Computer Design of Transducers". U.S. Navy Journal of Underwater Acoustics. Department of the Navy ...
CS1 maint: discouraged parameter (link) Murty, D.V.S. (2009). Transducers & Instrumentation (2nd ed.). New Delhi: Prentice-Hall ...
"MEMS Barometric Pressure Sensor". Sensors & Transducers E-Digest. 92 (4). 2008. Retrieved 13 June 2014. This Is the Samsung ...
v. ISBN 0-8247-4245-1. Bobber, R. J. (1981). "New Types of Transducers". Underwater Acoustics and Signal Processing. p. 243. ...
TRANSDUCERS & EUROSENSORS XXVII). pp. 578-581. doi:10.1109/Transducers.2013.6626832. ISBN 978-1-4673-5983-2. "EAGER: ... 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems ( ...
Transducers and Measurement Lab. Process Automation Lab. Instrumentation Software and Simulation Lab. Digital electronics and ... Transducers & Measurement and Communication for academic development of students with Wi-Fi facility & separate departmental ...
... s are a type of spray nozzle that uses high frequency vibration produced by piezoelectric transducers acting ... Carstens, James (1993). Electrical sensors and transducers. Regents/Prentice Hall. pp. 185-199. ISBN 978-0132496322. Berger, ...
TRANSDUCERS). pp. 1877-80. doi:10.1109/TRANSDUCERS.2015.7181316. ISBN 978-1-4799-8955-3. S2CID 7243537. Malone, Evan; Lipson, ... In electronic engineering, actuators are a subdivision of transducers. They are devices which transform an input signal (mainly ... 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems ( ...
p. 9. ISBN 0-7506-7269-2. Signals come from transducers... Miller, Mark R. (2002). Electronics the Easy Way. Barron's ... to an electrical signal by a transducer which converts one type of energy into another (e.g. a microphone). The signals take ...
doi:10.1109/TRANSDUCERS.2011.5969506. ISBN 978-1-4577-0157-3. Ando, B.; Baglio, S.; Marletta, V.; Pistorio, A. (2014). 2014 ...
Torsional vibration . Toughness . Trajectory . Transducer . Transformer . Trigonometric functions . Trigonometry . Trimean The ...
"transducer". Online Etymology Dictionary. Retrieved 2012-07-31. Harper, Douglas. "transduce". Online Etymology Dictionary. ...
Sherlock, R. A. (1970). "Oscillating Superleak Second Sound Transducers". Review of Scientific Instruments. 41 (11): 1603-1609 ... Oscillating superleak transducers (OST) use second sound to locate defects in superconducting accelerator cavities. Third sound ... "Response of an oscillating superleak transducer to a pointlike heat source". Physical Review Special Topics: Accelerators and ...
Acoustics: Sound Fields and Transducers. Elsevier, Oxford, First edition, 2012. ISBN 0-123-91421-3 Building 20 Beranek, Leo ( ... Sound Fields and Transducers. He was also an expert in the design and evaluation of concert halls and opera houses, and ... Sound Fields and Transducers. His famous adage was Beranek's Law about psychological effect of somebody's own design and ...
Most micromachines act as transducers; in other words, they are either sensors or actuators. Sensors convert information from ...
Molecular electronic transducers (MET) are a class of inertial sensors (which include accelerometers, gyroscopes, tilt meters, ... vol.31, p. 474 (1959). C. W. Larkam, "Theoretical Analysis of the Solion Polarized Cathode Acoustic Linear Transducer", J. ... meters Seismic sensors Seismometers Angular accelerometers Angular rate sensors Gyroscopes Tiltmeters Pressure transducers "MET ...
The volume near the transducer which exhibits this phenomenon is called the near field, as opposed to the far field where wave ... Acoustic waves emitted by ultrasonics transducer crystals exhibit a property known as self-focusing (or natural focusing). Note ... Dreyer, T.; Krauss, W.; Bauer, E. & Riedlinger, R.E. (October 2000). "Investigations of compact self focusing transducers using ... from the electronically controlled focusing employed in diagnostic ultrasound devices which employ arrays of transducers. The ...
A large amount of miniature single-channel absolute and differential pressure transducers is available as well. The transducers ... Pneumatic Transducers The lab possess three 16-channel PSI 9116 units from Pressure Systems Inc with a 500 Hz sampling ... All pressure transducers are currently incorporated into an automated data communication and measurements protocol.​ ...
Electromagnetic acoustic transducer (EMAT) is a transducer for non-contact sound generation and reception using electromagnetic ... EMAT transducers typically produce raw signal of lower power than piezoelectric transducers. As a result, more sophisticated ... Although there are EMAT transducers as small as a penny, commonly used transducers are large in size. Low-profile EMAT problems ... Comparison with piezoelectric transducers[edit]. As an ultrasonic testing (UT) method, EMAT has all the advantages of UT ...
... and an ultrasound transducer. The ultrasound transducer is configured for transmitting and receiving signals and for imaging of ... Transducer 180 is similar to transducer 22 described in conjunction with earlier Figures. Further, transducer 180 may be an ... Transducer 330 receives the electrical signal as voltage applied across opposing surfaces of transducer 330. The transducer ... In such an embodiment, transducer 22 would comprise a side-looking transducer facing side hole 12. In this manner, transducer ...
Transducers Radar Panoptix ActiveCaptain™ Entertainment Fishfinders Instruments & Instrument Packs Coastal Fishing Discontinued ... To find the right transducer for your needs, simply use the filters below. First select your product to ensure compatibility, ...
Easily navigate Digi-Keys large selection of sensors and transducers to quickly find the components needed to complete your ...
and the transducer 54. to encapsulate the transducer 54. . [0057] Application of a voltage to the transducer 54. , which in FIG ... The booster transducer 222. may be a piezoelectric transducer similar to the transducer 54. , 54. ″ or 54. ″′ respectively ... while reducing the force produced by the transducer 54. , 54. ′, 54. ″ and 54. ″′, in principle the area of the transducer 54. ... Alternatively, the booster transducer 222. may be an electromagnetic transducer, a speaker such as those used in conventional ...
... electromechanical transducer: any type of device that either converts an electrical signal into sound waves (as in a ... loudspeaker) or converts a sound wave into an electrical signal (as in the microphone). Many of the transducers used in ... In transducer. An electroacoustic transducer may convert electrical signals to acoustic signals or vice versa. An example is ... A photoelectric transducer reacts to visible light to produce electrical energy. Electromagnetic transducers form a… ...
Buy OMEGA Transducers. Newark offers fast quotes, same day shipping, fast delivery, wide inventory, datasheets & technical ...
Industry Standard Transducers can be used with other manufacturers equipment that conforms to the Industry standard.Smart ... Transducers include a feature that allows them to self identify themselves to an Expert EXTA Torque Analyzer for easy set-up. ... Smart Torque plus Angle Transducers include an encoder to measure angle. ... Expert Transducers, available in stationary and rotary styles, are designed for use with the Expert EXTA Torque Analyzer or ...
... und Sensortechnik is exhibiting the product Torque transducers at HANNOVER MESSE from 23 to 27 Apr. 2018 in Hannover, Germany. ... Rotary displacement transducers Sensors to measure rotary displacement and absolute positions. Ranges from +/-10degree to +/- ... Amplifiers with DC-excitation for transducers with strain gages or piezoresistive sensores. -Amplifiers with carrying frequency ...
48800V and 49800V Series Digital Torque Transducers from S. Himmelstein and ... Announcing the ultra-precise MCRT® 48800V and 49800V Series Digital Torque Transducers from S. Himmelstein and Company. These ... These newly-designed torque transducers are well-suited for a broad range of high-precision applications including both ...
Transducers International is top specialist in selling world-wide Brand New & Used transducers from all brands and offers ... transducer repair for all major manufactures incl. TEE repair. ... Transducers International was founded in 2007 as a Dutch family ... Transducers International is top specialist in selling world-wide Brand New, Used & Refurbished ultrasound transducers from all ... Transducers-International. Jan Ruissen, Transducers International. DOTmed user since June 2008. Dorpstraat 22. Ulvenhout, ...
Wholesale transducers UK trade directory of transducer products and stocks and closeout supplies - Find and contact UK ... Wholesale UK-Wholesale Products-Wholesale Suppliers-Wholesale Transducers-Transducer Suppliers-Trade Leads-My eSources ...
APGs PT-400 amplified output pressure transducers cover pressures from 0 to 20,000psi, high-burst pressure to 3x full scale ... The transducers weigh 10 oz. and offer standard 4-20mA, 0-5 VDC and 0-10 VDC outputs. Their integrated electronics are fully ... Suitable for static and dynamic pressure measurement where an amplified output signal is desired, the transducers are cCSAus- ... APGs PT-400 amplified output pressure transducers cover pressures from 0 to 20,000psi, high-burst pressure to 3x full scale ...
... www.ferret.com.au showcases products from suppliers of Temperature Transducers and other related products and services. ... Melt pressure transducers from Bestech Australia. 13/10/08 - Bestech Australia have introduced a range of melt pressure and ... Combination Temperature pressure transducers with USB connection from Pacific Sensor Technologies. 31/03/11 - The 9150USB ... Combination pressure and temperature transducers from Pacific Sensor Technologies. 17/08/10 - Now available from Pacific Sensor ...
Sensors and transducers are key to providing accurate control. Emerson offers retailers a complete line of sensors to augment ... Information on temperature, humidity, and light level sensors, refrigerant transducers, indoor air quality monitoring, and more ...
Because of their broadband response thin sheet PVDF transducers have been shown to be ideal for monitoring the true form of ... Underwater Acoustic Measurements on Polyvinylidene Fluoride Transducers. B. Woodward and R. C. Chandra ... Methods of making piezoelectric transducers from very thin sheets of polyvinylidene fluoride (PVDF) are discussed, together ... is also given to the dependence of receiving response on the poling fields and temperatures used in making PVDF transducers. ...
Smart Transducers. Acronym:. SMART. Version:. 1.0. Publication Date:. January 2003 Categories:. * Corba Embedded Intelligence ...
The problems of development of high-temperature ultrasonic transducers for modern science and technology applications are ... Design peculiarities of the transducers are reviewed. Commercial sensors in the meanwhile are often characterized with poor ... The problems of development of high-temperature ultrasonic transducers for modern science and technology applications are ...
EYC-Tech is exhibiting the product Temperature measuring transducers at HANNOVER MESSE from 23 to 27 Apr. 2018 in Hannover, ... Measuring transducers Measuring phasyical are including humidity, temperature, dew point, frost-point, wet-bulb temperature, ... Temperature Transducers/Transmitters. Measuring phasyical are including humidity, temperature, dew point, frost-point, wet-bulb ... Sensors for relative humidity(gas humidity) Humidity Transducers/Transmitters. Measuring phasyical are including humidity, ...
Some examples include at least one capacitive micro-electro-mechanical transducer (cMUT). For instance, the cMUT may include a ... In addition to discrete ultrasound transducers, ultrasound transducer arrays containing multiple transducers have been also ... This improves the transducer sensitivity.. (4) The transducer breakdown voltage can be improved by using a proper material for ... Micro-electro-mechanical transducers. 2012-08-21. Huang. 310/309. 7564172. Micro-electro-mechanical transducer having embedded ...
Smart Transducers. This document describes the specification for a set of smart transducer interfaces that supports the ... An encapsulation of the internal complexity of the generic smart-transducer hardware and software and the internal transducer ... configure and diagnose a generic transducer device. ... Smart Transducers. Acronym:. SMART. Version:. 1.0 Document ...
The transducer element may function as a transmitter. When used as a transmitter, the electrodes are electrically connected to ... A miniature piezoelectric transducer element is provided, comprising: (a) a cell element having a cavity; (b) a flexible ... Piezoelectric transducer. US20110190669 *. 8 Apr 2011. 4 Aug 2011. Bin Mi. Ultrasonic transducer for a metallic cavity ... The transducer element of claim 1. , wherein said transducer element is used for converting acoustic energy into electrical ...
... and transducer means responsive to differential movement between the elongate members for producing a signal in dependence upon ... A pressure transducer comprising an elongate hollow outer housing having a pressure sensor diaphragm and externally positioned ... 3. A pressure transducer according to claim 1 in which the transducer means is arranged to produce an electrical signal in ... 7. A pressure transducer according to claim 6 in which the transducer means comprises a strain gauge element which is arranged ...
NPL provides calibration and certification of force transducers, including overload and bearing pad tests, to national and ... NPL provides calibration and certification of force transducers, including overload and bearing pad tests, to national and ...
Viatran announced the availability of their new Model 511 Hammer Union Pressure Transducer. This design has addressed the needs ...
xSonic Pigtail Transducer Wiring Block Adapter xSonic Pigtail Transducer Wiring Block Adapter ... Transom-mount, 50 kHz/200 kHz Broadband and DownScan™ Transducer HDI 50/200/455/800kHz Skimmer Transducer ... Transom-mount, 50 kHz/200 kHz Broadband and DownScan™ Transducer HDI 50/200/455/800kHz Skimmer Transducer ... Transom-mount, 50 kHz/200 kHz Broadband and DownScan™ Transducer HDI 50/200/455/800kHz Skimmer Transducer ...
Force Sensors / Transducers. SWIFT® Evo Wheel Force Transducer comes with new graphical user interface.. Meeting SAE J267 and ... Force Sensors / Transducers. New AxialTQ Torque Transducer Enables Real-time Control and Data Collection. Available with analog ... Force Sensors / Transducers. New SX-4462 Hall Effect Torque Sensor Offers a Sensitivity of up to 0.4 V per Degree. The SX-4462 ... Force Sensors / Transducers. GT2-S Contact Sensors feature mounting brackets.. Available in 1 mm and 5 mm stroke lengths, GT2-S ...
  • Transducers International was founded in 2007 as a Dutch family business specialised in purchasing and selling medical ultrasound transducers. (dotmed.com)
  • Transducers International is top specialist in selling world-wide Brand New, Used & Refurbished ultrasound transducers from all brands and offers transducer repair for all major manufactures incl. (dotmed.com)
  • Transducers International matches each day continuously the demand and the availability of new, used and refurbished medical ultrasound transducers. (dotmed.com)
  • Due high capability, we are able to provide you in all your medical ultrasound transducers needs. (dotmed.com)
  • Sonosite creates ultrasound transducers with real-world customer needs in mind. (sonosite.com)
  • We're so confident in the durability of our ultrasound transducers that we created an industry-first warranty to cover them. (sonosite.com)
  • The table below lists available Fujifilm Sonosite ultrasound transducers. (sonosite.com)
  • The problems of development of high-temperature ultrasonic transducers for modern science and technology applications are analysed. (mendeley.com)
  • The present invention relates to a design and the method of constructing ultrasonic transducers and, in particular, a design and method for interconnecting elements in multiple elevation transducers. (google.com)
  • Ultrasonic transducers are used in many medical applications and, in particular, for the non-invasive acquisition of images of organs and conditions within a patient, typical examples being the ultrasound imaging of fetuses and the heart. (google.com)
  • The ultrasonic transducers used in such applications are generally hand held, and must meet stringent dimensional constraints in order to acquire the desired images. (google.com)
  • This invention relates to improving the radiation patterns of ultrasonic transducers. (google.es)
  • A liquid coupling between the piezoelectric transducer ( 54″, 54″′ ) and the diaphragm ( 82 ) or face ( 96 ) provides a mechanical impedance match for the transducer ( 54″, 54″′ ). (freepatentsonline.com)
  • 12. The device of claim 1 , wherein the transducer assembly is composed of piezoelectric transducer material with specific impedance characteristics. (google.com.au)
  • The transducer element may function as a transmitter. (google.ca)
  • 9. The transducer element of claim 1 , wherein said transducer element is used as a transmitter. (google.ca)
  • Industry Standard Transducers can be used with other manufacturers' equipment that conforms to the Industry standard.Smart Transducers include a feature that allows them to self identify themselves to an Expert EXTA Torque Analyzer for easy set-up.Smart Torque plus Angle Transducers include an encoder to measure angle. (ingersollrand.com)
  • Smart Transducers include a feature that allows them to self-identify themselves to an Expert EXTA Torque Analyzer for easy set-up. (ingersollrand.com)
  • Easily navigate Digi-Key's large selection of sensors and transducers to quickly find the components needed to complete your design or end-product. (digikey.com)
  • Sensors and transducers are key to providing accurate control. (emersonclimate.com)
  • The technology surrounding sensors and transducers is advancing at a rapid pace. (waterstones.com)
  • In this second edition of Sensors and Transducers, the latest advances are explored in a comprehensive collection of 105 recent papers, none of which were included in the book's first edition. (waterstones.com)
  • Editor Ronald Jurgen offers an informative introduction in Section I of Sensors and Transducers, clearly explaining the overall format and layout of the book. (waterstones.com)
  • Section IV, A look to the future offers a glimpse into where sensors and transducers have yet to lead us. (waterstones.com)
  • And, although there are many books on nanotechnology, recent advances in micro and nano-scale sensors and transducers are not adequately represented in most books. (routledge.com)
  • Micro- and Nano-Scale Sensors and Transducers provides a summary of the state of the art in sensor and transducer technology. (routledge.com)
  • 22/03/12 - Bestech Australia presents an innovative range of pressure temperature transducers designed to provide pressure and temperature outputs at a single process point. (ferret.com.au)
  • 31/03/11 - The 9150USB combination Pressure/Temperature transducers with direct USB 2.0 connection to data acquisition and test systems are now available from Pacific Sensor Technologies. (ferret.com.au)
  • 19/08/10 - Pacific Sensor Technologies offers the 9500 Series precision pressure and temperature transducers from Spectre Sensors. (ferret.com.au)
  • 17/08/10 - Now available from Pacific Sensor Technologies, the PST-SP1500 Pressure/Temperature Transducer incorporates all of the features the addition of a temperature output. (ferret.com.au)
  • 21/10/09 - Available from Pacific Sensor Technologies, PST-SP1500 combined pressure and temperature transducers combine all the features of the Model 1000 with the addition of a temperature output. (ferret.com.au)
  • 13/10/08 - Bestech Australia have introduced a range of melt pressure and temperature transducers, developed from strain gauge technology and with optimal price/ performance ratio. (ferret.com.au)
  • Pressure transducers suitable for monitoring such process pressures are known but known transducers tend to be somewhat inaccurate due for example to temperature dependence. (google.com)
  • The transducer can store up to 600,000 level, temperature, and time stamp measurements and is specifically designed to operate in any wireless environment, making it useful for remote installations. (manufacturing.net)
  • Temperature transducers are devices commonly used for measuring the temperature of a target object using a variety of methods. (articleinsider.com)
  • Temperature transducers, also called temperature sensors, must produce an output in correct proportion to the temperature input that they receive. (articleinsider.com)
  • Depending on their configuration, these transducers measure and display temperature in different ways. (articleinsider.com)
  • Another temperature transducer option is the thermocouple system. (articleinsider.com)
  • This transducer is based on the point where two different types of metals join and produce an electrical output in direct proportion to temperature. (articleinsider.com)
  • Temperature transducer, converts signals from resistance thermometers and resistors into 0/4-20 mA signals. (phoenixcontact.com)
  • Ex i temperature measuring transducer: Converts signals from resistance thermometers installed in Ex areas and transmits a 0/4-20 mA signal to a load in the safe area. (phoenixcontact.com)
  • Garmin's GT52HW-TM Transducer provides depth and temperature readings. (thegpsstore.com)
  • Garmin's GT23M-TM Mid-Band CHIRP Transom Mount Transducer provides depth and temperature readings. (thegpsstore.com)
  • Airmar Low Profile, 20° Tilted Element High Frequency, Wide Beam CHIRP Transducer with Depth and Temperature. (thegpsstore.com)
  • These newly-designed torque transducers are well-suited for a broad range of high-precision applications including both performance and endurance testing of engines, transmissions, drive systems, pumps, motors, servo motors, gearboxes, actuators, etc. (prweb.com)
  • Announcing the ultra-precise MCRT® 48800V and 49800V Series Digital Torque Transducers from S. Himmelstein and Company. (prweb.com)
  • BTS and WTS solutions enables torque transducers, load pins, load cells and multi-axis sensors to transmit output to a device, display, PC or other system. (thomasnet.com)
  • Groomed for aerospace hydraulic pumps and motors, the company's rotating torque transducers rely on non-contact, rotary transformers for sending excitation voltages to, and receiving measurement signals from, the strain gage sensor element. (electronicdesign.com)
  • 6. The transducer element of claim 2 , wherein said substrate includes a plurality of cell members. (google.ca)
  • A connection assembly for use in a multiple aperture ultrasonic transducer including an array of elements for transmitting and receiving wherein each element includes a plurality of segments and the connection assembly interconnects the segments of the elements and the segments to transmit/receive circuits. (google.com)
  • 3. A linear phased array ultrasonic transducer having X-axis and Y-axis shading along the array and perpendicular thereto comprising: a plurality of piezoelectric ceramic transducer elements each having electrodes on opposite surfaces, said array being generally elliptical and said elements having different mechanical lengths and elements at the ends are shorter than central elements, whereby the radiation pattern of said shaded array has reduced side lobe levels. (google.es)
  • A microelectromechanical transducer including a plurality of strips arranged in an array and maintained in a closely spaced relation by a plurality of spacers. (rti.org)
  • The waterMonitor datalogging level transducer is now available with an optional ETFE (ethylene tetrafluororethylene) jacketed cable for increased durability and corrosion resistance. (manufacturing.net)
  • 18/11/10 - Spectre Sensor's Model 9510U USB-enabled pressure transducers are available from Pacific Sensor Technologies. (ferret.com.au)
  • A pressure transducer comprising an elongate hollow outer housing having a pressure sensor diaphragm and externally positioned fixing means which facilitates pressure tight introduction of the diaphragm into a pressure sensing port provided in apparatus capable of generating pressures to be sensed, two. (google.com)
  • In Phase II we will optimize the transducer design and integrate a small preamplifier on the same chip as the sensor. (sbir.gov)
  • Teaching you how to make more informed selections of sensors or transducers for particular applications, it describes the differences between new sensor and transducer technologies based on nanotechnology and nano-fabrication and the older or "classical" sensor technologies. (routledge.com)
  • The position transducer LiView is generally suitable for all cylinder lengths and piston diameters - a state-of-the-art sensor system with smart technology for all of your cylinders. (liebherr.com)
  • Electromagnetic acoustic transducer ( EMAT ) is a transducer for non-contact sound generation and reception using electromagnetic mechanisms. (wikipedia.org)
  • was the invention of the acoustic transducer and the design of efficient acoustic projectors. (britannica.com)
  • 27/01/10 - Wago introduce their new family of 857 series transducers and relay modules available from NHP Electrical Engineering Products. (ferret.com.au)
  • These demanding applications are forcing pressure transducer manufacturers to include features in their products so that the device can operate in a hostile environment while maintaining a good price-performance ratio with excellent durability. (sae.org)
  • Innovative new products in the field of transducer development, signal conditioning and software are witness to our competence and up-to-date product know-how. (theengineer.co.uk)
  • Automation Products Group, Inc. (APG) introduces a new submersible pressure transducer, the Series PT-510W Wastewater Submersible Pressure Transducer. (environmental-expert.com)
  • Automation Products Group, Inc. (APG) introduced a new pressure transducer, the series PT-200 1% Industrial Pressure Transducer. (environmental-expert.com)
  • the only problem is to find the proper transducers to work in pulse-echo mode. (ndt.net)
  • These transducers are available in a multitude of sizes in 0.5 mm increments to ensure that the proper transducers are available for a variety of weld nugget sizes. (olympus-ims.com)
  • Our acoustic and vibration transducers are the result of our vast expertise and knowledge, backed up by meticulous testing and quality control. (bksv.com)
  • I'm planning to test very attenuative samples of plastic materials (both for flaw detection and thickness measurements), for which I should need very low frequency transducers (let's say in the range 100-250 KHz) of good performances to be used in pulse-echo mode because I have no access to both surfaces. (ndt.net)
  • Garmin Low Profile 20 degree tilt 1kW Medium Frequency CHIRP transducer. (thegpsstore.com)
  • Furuno SS75M12 Medium Frequency 12° Stainless Steel Thru-Hull CHIRP 600 Watt Transducer. (thegpsstore.com)
  • Garmin Low Profile 20 Degree 600W Medium Frequency CHIRP Bronze Thru-Hull Transducer. (thegpsstore.com)
  • Flickr: Discussing Garmin fish finder transducer question. (flickr.com)
  • Garmin fish finder transducer question. (flickr.com)
  • Garmin GT51M-TM 12-Pin 600W CHIRP (Mid-Band CHIRP 80-160kHz) and 500W (CHIRP 260/455kHz) ClearVu/SideVu Transom Mount Transducer. (thegpsstore.com)
  • Garmin's GT15M-IH In-Hull Mid-band CHIRP Transducer provides accurate depth readings and is compatible with Garmin STRIKER, echoMAP CHIRP, echoMAP Plus, echoMAP UHD, GPSMAP chartplotter/sonar combination units and GSD25. (thegpsstore.com)
  • Garmin GT8HW-IH In Hull CHIRP Transducer is designed to be mounted inside the hull of your boat. (thegpsstore.com)
  • Garmin's GT56UHD-TM Transducer pairs with specific Garmin units to provide exceptional Ultra High Definition images of fish and structure below and to the left and right of your vessel! (thegpsstore.com)
  • The PTN Analog Pressure Transducer Series features a stainless-steel housing and completely isolated sensing element for an extremely robust option for pneumatic and hydraulic applications. (norgren.com)
  • The transducers employ a flange and splined shaft design that conforms to AND 10262 and 20002, making them suitable for use in torque studies on cantilevered aerospace hydraulic motors and pumps. (electronicdesign.com)
  • The ultrasound transducer is configured for transmitting and receiving signals and for imaging of a body lumen so as. (google.ca)
  • The ultrasound transducer is configured for transmitting and receiving signals and for imaging of a body lumen so as to locate an ostium of a branch vessel and facilitate alignment of the stent side hole with the ostium. (google.ca)
  • An electroacoustic transducer may convert electrical signals to acoustic signals or vice versa. (britannica.com)
  • Available in ranges from vacuum through 0/20,000psi, the pressure transducer can be configured from a number of process connections, output signals and electrical termination options. (foodengineeringmag.com)
  • The AM4XX signal conditioning ICs and the AM337 pnp and npn interface switches process single-ended or differential output signals from a variety of transducers. (electronicproducts.com)
  • 7. A pressure transducer according to claim 6 in which the transducer means comprises a strain gauge element which is arranged to be responsive to differential movement between the elongate members to produce an electrical signal. (google.com)
  • 9. A pressure transducer according to claim 1 in which the transducer means comprises an optical detector arrangement responsive to differential movement between the elongate members, the optical detector arrangement including photo-detectors for enabling the production of an electrical signal. (google.com)
  • 7. The transducer of one of claims 1 through 3 and 4 through 6 further comprising multiple electrodes on the side thereof opposite the radiating surface, one of the multiple electrodes having a generally circular projection onto the plane. (google.co.uk)
  • Receiver-stimulators comprise a nearly isotropic transducer assembly, demodulator circuitry, and at least two tissue contacting electrodes. (google.com.au)
  • 1993). IPC No. U.S. Microelectromechanical transducer and fabrication method. (rti.org)
  • This invention relates to pressure transducers, especially to those used in processing industries such as plastics, rubber and food for sensing the pressure to which the materials are subjected during their forming processes. (google.com)
  • The present invention relates to an optoelectric transducer for converting solar energy into electric energy, and more specifically to a transducer comprising a solar cell, a heat conduction metal layer and a thermoelectric converter. (google.com.au)
  • Accordingly, an object of the present invention is to provide a novel optoelectric transducer for converting solar energy into electric energy at high efficiency. (google.com.au)
  • The present invention relates to an adaptor for a cannula guide type ultrasonic transducer probe for securing a disinfection cover on the ultrasonic transducer probe so as to prevent the probe from being contaminated. (google.co.uk)
  • Garmin's GT41-TM Transom Mount Transducer provides traditional sonar along with crisp, clear photo-like images below and to the sides of your boat. (thegpsstore.com)
  • Note that this is distinct from the electronically controlled focusing employed in diagnostic ultrasound devices which employ arrays of transducers. (wikipedia.org)
  • Providing a minimum of 10 million operating cycles with an accuracy of +/-0.25% FS in operating temperatures from -40ºF to 180ºF, APG's PT-400 amplified output pressure transducers cover pressures from 0 to 20,000psi, high-burst pressure to 3x full scale and overpressure to 2x full scale. (foodengineeringmag.com)
  • The new Rotork Fairchild T7500 range of transducers is specifically designed for these low pressure control systems with set point accuracy of 0.1%, even at pressures of less than 100 mBar. (environmental-expert.com)
  • Amplifiers with DC-excitation for transducers with strain gages or piezoresistive sensores. (hannovermesse.de)
  • Our extensive range covers everything from strain gages via measuring transducers to analog and digital amplifiers. (theengineer.co.uk)
  • Suitable for static and dynamic pressure measurement where an amplified output signal is desired, the transducers are cCSAus-certified for use in hazardous locations. (foodengineeringmag.com)
  • Meeting SAE J267 and J328 standards, SWIFT® Evo Wheel Force Transducer is suitable for use in Road Load Data Acquisition (RDLA), tire tread wear simulation, suspension dynamics characterization, durability testing, and advanced simulation and modeling. (thomasnet.com)
  • The transducer is suitable for connection to the Bridge Pod (5-pin audio connector). (adinstruments.com)
  • The transducer is suitable for connection to any ADInstruments Bridge Amp. (adinstruments.com)
  • This transducer is also available with an audio connector suitable for use with a Bridge Pod. (adinstruments.com)
  • The self-powered (three 130W amplifiers) Phoenix loudspeakers ($5400/pair) from Precision Transducer Engineering (PTE) aren't for sissies. (stereophile.com)
  • Sensors for relative humidity(gas humidity) Humidity Transducers/Transmitters. (hannovermesse.de)
  • The product overview "Pressure transmitters and pressure transducers" displays the transmitters and transducers from KELLER AG in a simple layout. (environmental-expert.com)
  • The radiation pattern of shaded single element piezoelectric transducers and transducer arrays has reduced side lobe levels. (google.es)
  • Unit supports Transducer Electronic Data Sheets (TEDS) and enhances cross talk, linearity and hysteresis performance. (thomasnet.com)
  • The TEDSdongle extends HBM's support of Transducer Electronic Data Sheet (TEDS) technology that ensures measurement chains can be automatically and securely recognised and configured. (theengineer.co.uk)
  • Viatran announced the availability of their new Model 511 Hammer Union Pressure Transducer. (spe.org)
  • Will a Airmar DST800 transducer fit in a Navman thru hull? (sailnet.com)
  • I have an old Navman speed transducer in a plastic thru hull (it can be taken out and replaced with a plug) that no longer works. (sailnet.com)
  • I'm hoping I can just replace it with an Airmar DST800 transducer - that the DST800 will fit water tight into the existing Navman thru-hull. (sailnet.com)
  • 10. A pressure transducer according to claim 9 in which the two elongate members each have a graticule secured thereto, illumination means being provided such that light shines through the graticules onto the photo-detectors whereby the electrical signal is produced consequent upon differential movement between the two elongate members. (google.com)
  • New from this company are its Models P792 and P892 low-range differential-pressure transducers, designed for use in VAV systems, fan static pressure, duct air flow, building pressurization, and filter monitoring applications. (esmagazine.com)
  • 10. The transducer element of claim 9 , further including a switching element electrically connected thereto so as to controllably change the mechanical impedance of said piezoelectric layer. (google.ca)
  • The distribution of Lorentz force is controlled by the design of magnet, and design of the electric coil, the properties of the test material, relative position between the transducer and the test part, and the excitation signal for the transducer. (wikipedia.org)
  • Design peculiarities of the transducers are reviewed. (mendeley.com)
  • I was wondering if the design of transducer has changed and that it has to be on the outside of the hull now? (flickr.com)
  • Some such organs can be reached by appropriately shaped probes inserted into body cavities and lumens, but the cavities and lumens pose size and shape restrictions on the probes that make transducer design much more difficult. (google.co.uk)
  • Our transducers have excellent signal-to-noise ratios due to broadband design, which is critical for distinguishing good welds from poor welds. (olympus-ims.com)
  • The versatile design of these spot weld transducers allows them to be used with either a soft membrane captive water column or a hard tip delay line. (olympus-ims.com)
  • R. Sklyar, "Superconducting organic and CNT FETs as a Biochemical Transducer," in Proceedings of the 14th International Symposium on Measurement and Control in Robotics (ISMCR '04) , IEEE, Houston, Tex, USA, September 2004. (hindawi.com)
  • R. Sklyar, "A SuFET based either implantable or non-invasive (Bio)transducer of nerve impulses," in Measurement and Control in Robotics , M. A. Armada, P. Gonzales de Santos, and S. Tachi, Eds. (hindawi.com)