Any device or element which converts an input signal into an output signal of a different form. Examples include the microphone, phonographic pickup, loudspeaker, barometer, photoelectric cell, automobile horn, doorbell, and underwater sound transducer. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Transducers that are activated by pressure changes, e.g., blood pressure.
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.
Photosensory rhodopsins found in microorganisms such as HALOBACTERIA. They convert light signals into biochemical information that regulates certain cellular functions such as flagellar motor activity.
A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.
The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.
A cytokine receptor that acts through the formation of oligomeric complexes of itself with a variety of CYTOKINE RECEPTORS.
A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues.
A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
The major protein constituents of milk are CASEINS and whey proteins such as LACTALBUMIN and LACTOGLOBULINS. IMMUNOGLOBULINS occur in high concentrations in COLOSTRUM and in relatively lower concentrations in milk. (Singleton and Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed, p554)
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. SOCS proteins contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-4. Stat6 has been shown to partner with NF-KAPPA B and CCAAT-ENHANCER-BINDING PROTEINS to regulate GENETIC TRANSCRIPTION of interleukin-4 responsive GENES.
Methods of creating machines and devices.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
Light driven chloride ion pumps that are ubiquitously found in halophilic archaea (HALOBACTERIALES).
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
The use of focused, high-frequency sound waves to produce local hyperthermia in certain diseased or injured parts of the body or to destroy the diseased tissue.
A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
The branch of physics that deals with sound and sound waves. In medicine it is often applied in procedures in speech and hearing studies. With regard to the environment, it refers to the characteristics of a room, auditorium, theatre, building, etc. that determines the audibility or fidelity of sounds in it. (From Random House Unabridged Dictionary, 2d ed)
Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.
A genus of rod-shaped, extremely halophilic HALOBACTERIACEAE which grows in alkaline conditions. They are strictly aerobic and some strains are motile. Natronobacterium is found in soda lakes, alkaline salterns, and soda soils.
The use of focused, high-frequency sound waves to destroy tissue. It is sometimes used in conjunction with but is distinct from INTERVENTIONAL ULTRASONOGRAPHY.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitogen-activated B-LYMPHOCYTES, and peripheral MONOCYTES. The receptors are heterodimers of the INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.
A cell line derived from cultured tumor cells.
A species of halophilic archaea found in salt lakes. Some strains form a PURPLE MEMBRANE under anaerobic conditions.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Established cell cultures that have the potential to propagate indefinitely.
Proteins found in any species of archaeon.
The design or construction of objects greatly reduced in scale.
A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
A Janus kinase subtype that is predominantly expressed in hematopoietic cell. It is involved in signaling from a broad variety of CYTOKINE RECEPTORS including ones that utilize the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT.
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics.
Processes that stimulate the GENETIC TRANSCRIPTION of a gene or set of genes.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Non-invasive imaging methods based on the mechanical response of an object to a vibrational or impulsive force. It is used for determining the viscoelastic properties of tissue, and thereby differentiating soft from hard inclusions in tissue such as microcalcifications, and some cancer lesions. Most techniques use ultrasound to create the images - eliciting the response with an ultrasonic radiation force and/or recording displacements of the tissue by Doppler ultrasonography.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
The movement of cells or organisms toward or away from a substance in response to its concentration gradient.
Small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
A semi-synthetic aminoglycoside antibiotic that is used in the treatment of TUBERCULOSIS.
Fenestra of the cochlea, an opening in the basal wall between the MIDDLE EAR and the INNER EAR, leading to the cochlea. It is closed by a secondary tympanic membrane.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
Cell surface proteins that bind interleukins and trigger intracellular changes influencing the behavior of cells.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)
The lymph fluid found in the membranous labyrinth of the ear. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Investigative and diagnostic methods and procedures based on the photoacoustic effect, which is the generation of SOUND WAVES from the absorption of ELECTROMAGNETIC RADIATION.
An implant used to replace one or more of the ear ossicles. They are usually made of plastic, Gelfoam, ceramic, or stainless steel.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Elements of limited time intervals, contributing to particular results or situations.
Specific molecular sites or structures on or in cells with which interferons react or to which they bind in order to modify the function of the cells. Interferons exert their pleiotropic effects through two different receptors. alpha- and beta-interferon crossreact with common receptors, while gamma-interferon initiates its biological effects through its own specific receptor system.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behavior of cells.
Electronic devices that increase the magnitude of a signal's power level or current.
A genus of HALOBACTERIACEAE whose growth requires a high concentration of salt. Binary fission is by constriction.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the COCHLEA. Towards the cochlear apex, the length of hair cell bodies and their apical STEREOCILIA increase, allowing differential responses to various frequencies of sound.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
A class of devices combining electrical and mechanical components that have at least one of the dimensions in the micrometer range (between 1 micron and 1 millimeter). They include sensors, actuators, microducts, and micropumps.
Proteins prepared by recombinant DNA technology.
Transport proteins that carry specific substances in the blood or across cell membranes.
Rhodopsins found in the PURPLE MEMBRANE of halophilic archaea such as HALOBACTERIUM HALOBIUM. Bacteriorhodopsins function as an energy transducers, converting light energy into electrochemical energy via PROTON PUMPS.
Glycoproteins found on the membrane or surface of cells.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
Hearing loss due to damage or impairment of both the conductive elements (HEARING LOSS, CONDUCTIVE) and the sensorineural elements (HEARING LOSS, SENSORINEURAL) of the ear.
Proteins found in any species of bacterium.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Use of reflected ultrasound in the diagnosis of intracranial pathologic processes.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Cell surface receptors formed from the dimerization of LIF RECEPTOR ALPHA SUBUNIT with CYTOKINE RECEPTOR GP130. Although originally described as receptors for LEUKEMIA INHIBITORY FACTOR these receptors also bind the closely-related protein ONCOSTATIN M and are referred to as both LIF receptors and type I oncostatin M receptors.
Gated transport mechanisms by which proteins or RNA are moved across the NUCLEAR MEMBRANE.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
LIGHT, it's processes and properties, and the characteristics of materials interacting with it.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
An interferon regulatory factor that recruits STAT1 PROTEIN and STAT2 PROTEIN heterodimers to interferon-stimulated response elements and functions as an immediate-early protein.
The motor activity of the GASTROINTESTINAL TRACT.
Rhodopsin molecules found in microorganisms such as ARCHAEA and PROTEOBACTERIA.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
The aggregation of soluble ANTIGENS with ANTIBODIES, alone or with antibody binding factors such as ANTI-ANTIBODIES or STAPHYLOCOCCAL PROTEIN A, into complexes large enough to fall out of solution.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.
Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.
Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.
Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Endogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= PLANT GROWTH REGULATORS).
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Imaging the temperatures in a material, or in the body or an organ. Imaging is based on self-emanating infrared radiation (HEAT WAVES), or on changes in properties of the material or tissue that vary with temperature, such as ELASTICITY; MAGNETIC FIELD; or LUMINESCENCE.
A neurotrophic factor that promotes the survival of various neuronal cell types and may play an important role in the injury response in the nervous system.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Triterpenes that derive from LANOSTEROL by a shift of the C19 methyl to the C9 position. They are found in seeds and roots of CUCURBITACEAE and other plants and are noted for intense bitterness.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.
An electrophoretic technique for assaying the binding of one compound to another. Typically one compound is labeled to follow its mobility during electrophoresis. If the labeled compound is bound by the other compound, then the mobility of the labeled compound through the electrophoretic medium will be retarded.
Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Enzymes that oxidize certain LUMINESCENT AGENTS to emit light (PHYSICAL LUMINESCENCE). The luciferases from different organisms have evolved differently so have different structures and substrates.
Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells' physiological response to that hormone. Mammary casein synthesis is one of the responses. The receptors are also found in placenta, liver, testes, kidneys, ovaries, and other organs and bind and respond to certain other hormones and their analogs and antagonists. This receptor is related to the growth hormone receptor.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
Restoration, reconstruction, or improvement of a defective or damaged LARYNX.
Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest.
The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The process by which two molecules of the same chemical composition form a condensation product or polymer.
CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CERCOPITHECUS AETHIOPS).)
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Projection of near-IR light (INFRARED RAYS), in the 700-1000 nm region, across an object in parallel beams to an array of sensitive photodetectors. This is repeated at various angles and a mathematical reconstruction provides three dimensional MEDICAL IMAGING of tissues. Based on the relative transparency of tissues to this spectra, it has been used to monitor local oxygenation, brain and joints.
Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons consisting of a polyisoprene backbone.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
Cell surface receptors with specificity for ONCOSTATIN M. Two subtypes of receptors have been identified and are defined by their subunit composition.
Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.
A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.
Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures. (1/1232)

We studied phasic right coronary blood flow in well trained normal dogs and dogs with pulmonic stenosis. We installed electromagnetic flow transducers and pressure tubes under anesthesia to monitor right coronary blood flow, cardiac output, central aortic blood pressure, and right ventribular pressure. In normotensive dogs, systolic flow amplitude equaled early diastolic flow levels. The ratio of systolic to diastolic flow at rest was substantially greater in the right coronary bed (36+/-1.3%) than in the left circumflex bed (13+/-3.6%). Right diastolid flow runoff, including the cove late in diastole, resembled left circumflex runoff. Blood flow to the normotensive right (37+/-1.1 ml/min 100(-1) g) and the left (35+/-1.0 ml/min(-1) g) ventricular myocardium indicated equal perfusion of both cardiac walls. Throttling of systolic flow was related directly to the right ventricular systolic pressure level in the dogs with pulmonic stenosis. Retrograde systolic flow occurred in severe right ventricular hypertension. The late diastolic runoff pattern in dogs with pulmonic stenosis appeared the same as for the normotensive dogs. We obtained systolic to diastolic flow ratios of 1/3 the value of normotensive hearts in high and severe pulmonic hypertension. Electrocardiograms and studies of pathology suggested restricted blood flow to the inner layers of the right myocardium in the dogs with severe and high right ventricular hypertension. Normotensive and hypertensive peak hyperemic flow responses were similar, except for an increased magnitude of diastolic flow, with proportionately less systolic flow in hypertensive states.  (+info)

Evaluation of the force-frequency relationship as a descriptor of the inotropic state of canine left ventricular myocardium. (2/1232)

The short-term force-frequency characteristics of canine left ventricular myocardium were examined in both isolated and intact preparations by briefly pertubing the frequency of contraction with early extrasystoles. The maximum rate of rise of isometric tension (Fmas) of the isolated trabeculae carneae was potentiated by the introduction of extrasystoles. The ratio of Fmas of potentiated to control beats (force-frequency ratio) was not altered significantly by a change in muscle length. However, exposure of the trabeculae to isoproterenol (10(-7)M) significantly changed the force-frequency ratio obtained in response to a constant frequency perturbation. Similar experiments were performed on chronically instrumented conscious dogs. Left ventricular minor axis diameter was measured with implanted pulse-transit ultrasonic dimension transducers, and intracavitary pressure was measured with a high fidelity micromanometer. Atrial pacing was performed so that the end-diastolic diameters of the beats preceding and following the extrasystole could be made identical. Large increases in the maximum rate of rise of pressure (Pmas) were seen in the contraction after the extrasystole. The ratio of Pmax of the potentiated beat to that of the control beat was not changed by a 9% increase in the end-diastolic diameter, produced by saline infusion. Conversely, isoproterenol significantly altered this relationship in the same manner as in the isolated muscle. Thus, either in vitro or in situ, left ventricular myocardium exhibits large functional changes in response to brief perturbations in rate. The isoproterenol and length data indicate that the force-frequency ratio reflects frequency-dependent changes in the inotropic state, independent of changes in length.  (+info)

Investigation of the theory and mechanism of the origin of the second heart sound. (3/1232)

To investigate further the origin of the second heart sound we studied human subjects, dogs, and a model in vitro of the cardiovascular system. Intra-arterial sound, pressure, and, where possible, flow and high speed cine (2,000 frames/sec) were utilized. The closure sound of the semilunar valves was of higher amplitude in be ventricles than in their respective arterial cavities. The direction of inscription of the main components of intra-arterial sound were opposite in direction to the components of intraventricular sound. Notches, representative of pressure increments, were noted on the ventricular pressure tracings and were coincident with the components of sound. The amplitude of the closure sound varied with diastolic pressure, but remained unchanged with augmentation of forward and retrograde aortic flow. Cines showed second sound to begin after complete valvular closure, and average leaflet closure rate was constant regardless of pressure. Hence, the semilunar valves, when closed, act as an elastic membrane and, when set into motion, generate compression and expansion of the blood, producing transient pressure changes indicative of sound. The magnitude of the initial stretch is related to the differential pressure between the arterial and ventricular chambers. Sound transients which follow the major components of the second sound appear to be caused by the continuing stretch and recoil of the leaflets. Clinically unexplained findings such as the reduced or absent second sound in calcific aortic stenosis and its paradoxical presence in congenital aortic stenosis may be explained by those observations.  (+info)

Filter-based coded-excitation system for high-speed ultrasonic imaging. (4/1232)

We have recently presented a new algorithm for high-speed parallel processing of ultrasound pulse-echo data for real-time three-dimensional (3-D) imaging. The approach utilizes a discretized linear model of the echo data received from the region of interest (ROI) using a conventional beam former. The transmitter array elements are fed with binary codes designed to produce distinct impulse responses from different directions in ROI. Image reconstruction in ROI is achieved with a regularized pseudoinverse operator derived from the linear receive signal model. The reconstruction operator can be implemented using a transversal filter bank with every filter in the bank designed to extract echoes from a specific direction in the ROI. The number of filters in the bank determines the number of image lines acquired simultaneously. In this paper, we present images of a cyst phantom reconstructed based on our formulation. A number of issues of practical significance in image reconstruction are addressed. Specifically, an augmented model is introduced to account for imperfect blocking of echoes from outside the ROI. We have also introduced a column-weighting algorithm for minimizing the number of filter coefficients. In addition, a detailed illustration of a full image reconstruction using subimage acquisition and compounding is given. Experimental results have shown that the new approach is valid for phased-array pulse-echo imaging of speckle-generating phantoms typically used in characterizing medical imaging systems. Such coded-excitation-based image reconstruction from speckle-generating phantoms, to the best of our knowledge, have not been reported previously.  (+info)

Use of high-intensity focused ultrasound to control bleeding. (5/1232)

OBJECTIVE: High-intensity focused ultrasound (HIFU) has been shown to be effective in controlling hemorrhage from punctures in blood vessels. The objective of the current study was to investigate the capability of HIFU to stop bleeding after a more severe type of vascular injury, namely longitudinal incisions of arteries and veins. METHODS: The superficial femoral arteries, common femoral arteries, carotid arteries, and jugular veins of four anesthetized pigs were exposed surgically. A longitudinal incision, 2 to 8 mm in length, was produced in the vessel. HIFU treatment was applied within 5 seconds of the onset of the bleeding. The HIFU probe consisted of a high-power, 3.5-MHz, piezoelectric transducer with an ellipsoidal focal spot that was 1 mm in cross section and 9 mm in axial dimension. The entire incision area was scanned with the HIFU beam at a rate of 15 to 25 times/second and a linear displacement of 5 to 10 mm. A total of 76 incisions and HIFU treatments were performed. RESULTS: Control of bleeding (major hemosatsis) was achieved in all 76 treatments, with complete hemostasis achieved in 69 treatments (91%). The average treatment times of major and complete hemostasis were 17 and 25 seconds, respectively. After the treatment, 74% of the vessels in which complete hemostasis was achieved were patent with distal blood flow and 26% were occluded. The HIFU-treated vessels showed a consistent coagulation of the adventitia surrounding the vessels, with a remarkably localized injury to the vessel wall. Extensive fibrin deposition at the treatment site was observed. CONCLUSION: HIFU may provide a useful method of achieving hemostasis for arteries and veins in a variety of clinical applications.  (+info)

Laparoscopy-assisted intrapelvic sonography with a high-frequency, real-time miniature transducer for assessment of the Fallopian tube: a preliminary report. (6/1232)

Our purpose was to visualize normal and abnormal Fallopian tubes using laparoscopy-assisted intrapelvic sonography with a specially developed 20 MHz flexible catheter-based high-resolution, real-time miniature (2.4 mm outer diameter) ultrasound transducer in infertile women. A total of 21 women (20 infertile, one with unilateral hydrosalpinx, and one tubal pregnancy) were studied with pelvic saline effusion under laparoscopy. Fimbriae were clearly depicted with a cockscomb-like form in 95% of patients. All ampullae were visualized, and mucosal layers were clearly distinguished from muscle layers in 70% of patients. Scanty intratubal effusion was noted in 50% of patients, and tubal spastic findings were found in 10% of patients. In all, 60% of isthmuses were detected, and mucosal layers were distinguished from muscle layers in 30%. In the subject with hydrosalpinx, the tubal wall was thinner, and it was not possible to distinguish between muscle and mucosal layers. In the subject with a tubal pregnancy, the amniotic membrane and decidua were depicted more clearly than by transvaginal sonography. In conclusion, laparoscopy-assisted intrapelvic sonography with a high-frequency, real-time miniature transducer may be useful in the assessment of tubal texture and function in tubal disorders, possibly in infertility practice.  (+info)

Metabolic cost of generating horizontal forces during human running. (7/1232)

Previous studies have suggested that generating vertical force on the ground to support body weight (BWt) is the major determinant of the metabolic cost of running. Because horizontal forces exerted on the ground are often an order of magnitude smaller than vertical forces, some have reasoned that they have negligible cost. Using applied horizontal forces (AHF; negative is impeding, positive is aiding) equal to -6, -3, 0, +3, +6, +9, +12, and +15% of BWt, we estimated the cost of generating horizontal forces while subjects were running at 3.3 m/s. We measured rates of oxygen consumption (VO2) for eight subjects. We then used a force-measuring treadmill to measure ground reaction forces from another eight subjects. With an AHF of -6% BWt, VO2 increased 30% compared with normal running, presumably because of the extra work involved. With an AHF of +15% BWt, the subjects exerted approximately 70% less propulsive impulse and exhibited a 33% reduction in VO2. Our data suggest that generating horizontal propulsive forces constitutes more than one-third of the total metabolic cost of normal running.  (+info)

Lumbar intradiscal pressure after posterolateral fusion and pedicle screw fixation. (8/1232)

In vitro biomechanical testing was performed in single-functional spinal units of fresh calf lumbar spines, using pressure needle transducers to investigate the effect of posterolateral fusion (PLF) and pedicle screw constructs (PS) on intradiscal pressure (IDP), in order to elucidate the mechanical factors concerned with residual low back pain after PLF. IDP of 6 calf lumbar spines consisting of L4 and L5 vertebrae and an intervening disc was measured under axial compression, flexion-extension and lateral bending in the intact spine, PS, PLF and the destabilized spine. Relative to the intact spines, the destabilized spines showed increased IDP in all of lordings and moments. IDP under PS and PLF were significantly decreased in axial compression, extension and lateral bending loads (p<0.05). In flexion, IDP under PS and PLF increased linearly proportional to the magnitude of flexion moment and reached as high as IDP of the intact spines. These results demonstrated that despite an increase in the stiffness of motion segments after PLF and PS, significant high disc pressure is still generated in flexion. Flexibility of PS and PLF may cause increased axial load sharing of the disc in flexion and increased IDP. This high IDP may explain patients' persisting pain following PS and PLF.  (+info)

In the last two decades, capacitive micromachined ultrasonic transducers (CMUTs) have proven themselves to be promising for various ultrasound imaging and chemical sensing applications. Although holding many benefits for ultrasound imaging, CMUTs have certain weaknesses such as the relatively low output pressure at transmission, which hinder their development in the diagnostic imaging application. In the sensing area, CMUTs have shown attractive features such as high mass sensitivity, miniaturized array configuration, and ease of functionalization. However, their potential for humidity sensing is less explored. The objectives of this thesis lie in two aspects. One is to offer a solution to overcome the limitation of low output pressure, and the other is to develop CMUTs as resonant gravimetric humidity sensors. The major efforts are made on the second task. For the first objective, a novel dual-element ultrasonic transducer is proposed. It incorporates two transducer technologies by using a ...
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Photoacoustic imaging combines the contrast advantage of pure optical imaging and the resolution advantage of pure ultrasonic imaging. It has become a popular research subject at present. A fast photoacoustic imaging system based on multi-element linear transducer array and phase-controlled focus method was developed and tested on phantoms and tissues. A Q switched Nd:YAG laser operating at 532nm was used in our experiment as thermal source. The multi-element linear transducer array consists of 320 elements. By phase-controlled focus method, 64 signals, one of which gathered by 11-group element, make up of an image. Experiment results can map the distribution of the optical absorption correctly. The same transducer array also can operate as a conventional phase array and produced ultrasound imaging. Compared to other existing technology and algorithm, the PA imaging based on transducer array was characterize by speediness and convenience. It can provide a new approach for tissue functional ...
In this thesis a design of a CMOS transimpedance amplifier (TIA) for a capacitive micro-machined ultrasonic transducer (CMUT) is presented. CMUTs have a high electrical impedance when used as receivers. Any capacitance between the CMUT and a high impedance amplifier will degrade the frequency response. So, we need to amplify the current rather than the voltage. This approach requires a transimpedance amplifier. The designed TIA has a 30 MHz bandwidth and 400 kΩ transimpedance gain. The total input referred current noise of the TIA is 270 fA/√Hz at 10 MHz. The noise figure of the TIA is 2.7 dB at 10 MHz when connected to the CMUT with 200 kΩ source resistance. The power consumption of the TIA is 10.5 mW and the size of the TIA layout is 133µm x 45µm. The TIA chip will be fabricated in AMS C35B4C3 (0.35µm) process ...
A miniature piezoelectric transducer element is provided, comprising: (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter. When used as a transmitter, the electrodes are electrically connected to an electrical circuit including a switching element for modulating the reflected
According to the present invention, there is provided an ultrasound therapy system comprising: an annular array ultrasound transducer having a plurality of ring transducer elements arranged concentrically, for transmitting an ultrasound beam in response to drive signals applied thereto, and for outputting echo signals in response to an ultrasound beam as received; transmitting/receiving means for generating and supplying drive signals to said transducer elements to cause said ultrasound transducer to transmit an ultrasound beam for imaging and an ultrasound beam for treatment, and for processing echo signals from said transducer elements corresponding to the received ultrasound beam; and beam pattern control means, provided in said transmitting/ receiving means, comprising means for delaying at least one of the drive signals for driving said transducer elements and the echo signals output from said transducer elements in accordance with a selected one of predetermined delay patterns, thereby ...
An improved method for fabrication of a multiple-element piezoelectric transducer and the transducer produced thereby. A green precursor tape is produced by doctor-blade tape-casting of a slurry containing lead zirconate-titanate (PZT) powder. After drying, individual strips of the tape are stacked between flat plates of previously sintered PZT, and sintered to form PZT strips; Pb from the previously sintered PZT plates makes up any Pb lost from the surfaces of the tape strips during sintering. The PZT strips are stacked interposed by layers of a thermoplastic polymer, and heated to a temperature above the melting point of the polymer, forming a laminate block. This block is then sliced perpendicular to the plane of the layers, forming slabs of alternate PZT and polymer layers; the slabs are then sliced perpendicular to the first slicing planes, forming strips of alternating PZT and polymer material. Electrodes are then added to complete the transducer assembly.
1D model of piezoelectric transducers based on a piezoelectric element vibrating in thickness mode with a backing block and a stack of impedance matching layers on the radiating surface . The model calculates the electrical impedance, the electrical response when a plane wave impignes on the transducer surface and the surface displacement when the transducer…
Frequency characteristics of ultrasound detectors used in optoacoustic tomography have a major impact on imaging performance. It is common practice to select transducers based on their sensitivity at the central frequency and under normal incidence. However, the bandwidth and angular sensitivity play an equally important role in establishing the quality and accuracy of the reconstructed images. Here, we developed a calibrated optoacoustic characterization method specifically tailored for broadband measurements of the angular transducer sensitivity (directivity). Ultrawideband omnidirectional optoacoustic responses were generated by uniformly illuminating thin absorbing sutures with nanosecond laser pulses and characterized with a needle hydrophone. This calibrated optoacoustic source was used to characterize the frequency dependence of the angular response by a conventional piezoelectric transducer (PZT) and a capacitive micromachined ultrasonic transducer (cMUT) with similar size and central ...
TY - JOUR. T1 - Advances in energy harvesting using low profile piezoelectric transducers. AU - Priya, Shashank. N1 - Funding Information: Acknowledgement The author is grateful for the support from Texas ARP grant 003656-0010-2006.. PY - 2007/9. Y1 - 2007/9. N2 - The vast reduction in the size and power consumption of sensors and CMOS circuitry has led to a focused research effort on the on-board power sources which can replace the batteries. The concern with batteries has been that they must always be charged before use. Similarly, the sensors and data acquisition components in distributed networks require centralized energy sources for their operation. In some applications such as sensors for structural health monitoring in remote locations, geographically inaccessible temperature or humidity sensors, the battery charging or replacement operations can be tedious and expensive. Logically, the emphasis in such cases has been on developing the on-site generators that can transform any available ...
2. The ultrasound diagnostic apparatus according to claim 1, comprising:the cap whose outer periphery contacts the cavity wall directly or via the medium outside the cap;the ultrasound transducer including the electromechanical transducer element and the lens in a concave shape provided on the electromechanical transducer element, rotatable or swingable around a center axis of the cap, capable of transmitting ultrasound with the electromechanical transducer element as the sound source and/or receiving echo from the subject area via the cap, and provided in the cap; andan acoustic medium which is filled between an inner surface of the cap and the ultrasound transducer in the cap, and a sound velocity in the acoustic medium is lower than that in the medium outside the cap,whereinthe acoustic lens focuses the ultrasound transmitted from the electromechanical transducer element, and includes a shape in which a first focal length of a first lens surface on a section parallel with the ultrasound ...
A string instrument pickup system sensitive to 360 of transverse string movement, which is substantially immune from microphonics, and which has a substantially equal or balanced response to all of the strings. In one form of the invention a piezoelectric transducer is compressively associated with vertical movement components of each string of the instrument, but is laterally offset from a centered position under the string for compressive association of the transducer also with the horizontal string movement components; and halves of the total piezoelectric transducer area are oppositely polarized so as to cancel out microphonics. In a modular form of the invention a plurality of the piezoelectric transducers are supported in an elongated array by means of a flexible body of electrically insulative material and a pliable outer wrapping of metal foil so that the transducer is conformable to distortions and deformations in string saddle and bridge elements of the instrument between which the modular
TY - JOUR. T1 - CMUT Electrode Resistance Design: Modelling and Experimental Verification by a Row-Column Array. AU - Havreland, Andreas Spandet. AU - Engholm, Mathias. AU - Tomov, Borislav Gueorguiev. AU - Jensen, Jørgen Arendt. AU - Hansen, Ole. AU - Thomsen, Erik Vilain. PY - 2019. Y1 - 2019. N2 - This paper addresses the importance of having control over the resistivity of the electrodes for capacitive micromachined ultrasonic transducers (CMUT) devices. The electrode resistivity can vary depending on the fabrication technology used, and resistivity control becomes especially important in the cases where metal electrodes can not be used. This raises the question: When is the resistivity of an electrode sufficiently low? To answer this question we have developed a simple design criterion. The criterion describes the attenuation of AC signals along a CMUT element. It is shown that the non-dimensional product between angular excitation frequency, resistance, and capacitance ωRC of an element ...
Capacitive micromachined ultrasonic transducers (CMUT) are typically used as arrays consisting of separate cells or interconnected sub arrays, and these cells have several operation modes. Design procedure and measurements were presented for an airborne CMUT cell without a DC bias. In unbiased mode, the plate motion spans the entire gap without collapsing. The frequency of sinusoidal electrical input signal is half of the resulting acoustical output signal. A large plate swing can be obtained at low excitation voltages using the entire remaining gap. In this work, a design procedure of arrays with unbiased operation mode is derived. Designs are validated by means of simulations and measurements on fabricated CMUTs. The problems associated with beamforming are resolved. Use of this operation mode in an array configuration enables larger acoustical power output. A better transmitted signal waveform definition is obtained when pulse width modulation (PWM) is employed.. In the design process of ...
Stanford University Oral Defense - Department of Electrical Engineering Speaker: Amin Nikoozadeh Title: Intracardiac Ultrasound Imaging Using Capacitive Micromachined Ultrasonic Transducer (CMUT) Arrays Advisor: Professor B. T. Khuri-Yakub Date: Friday, June 04, 2010 Time: 09:30 AM (Refreshments at 9:15 AM) Location: Clark Center Auditorium (Basement, entrance across from Nexus) Map: http://ucomm.stanford.edu/map/?q=Clark%20Center ,http://ucomm.stanford.edu/map/?q=Clark%20Center&sf=a.BLDG_NAME, &sf=a.BLDG_NAME ABSTRACT Atrial fibrillation, the most common type of cardiac arrhythmia, now affects more than 2.2 million adults in the US alone. Currently, electrophysiological interventions are performed under fluoroscopic guidance, which does not provide adequate soft-tissue resolution and exposes the patient and the operator to harmful ionizing radiation. Intracardiac echocardiography (ICE) provides real-time anatomical information that has proven valuable in reducing the fluoroscopy time and ...
Piezoelectric ultrasonic transducers are available in a wide range of shapes like disks, plates or tubes, and different performance levels.
This press release contains forward-looking statements within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, projections about our business and our future revenues, expenses and profitability. Forward-looking statements may be, but are not necessarily, identified by the use of forward-looking terminology such as may, anticipates, estimates, expects, intends, plans, believes, and words and terms of similar substance. Forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause the actual events, results, performance, circumstances or achievements of the Company to be materially different from any future events, results, performance, circumstances or achievements expressed or implied by such forward-looking statements. Such forward-looking statements include statements relating to the Company exploring strategic ...
Forward-Looking Statements The information in this press release contains forward-looking statements and information within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the safe harbor created by those sections. These forward-looking statements include, but are not limited to, statements concerning the anticipated launch of DecisionDx-SCC. The words anticipates, believes, estimates, expects, intends, may, plans, projects, will, would and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. We may not actually achieve the plans, intentions, or expectations disclosed in our forward-looking statements and you should not place undue reliance on our forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations ...
Cautionary Statement on Forward-looking Information. Certain statements in this press release that are forward-looking and not statements of historical fact are forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are forward-looking information within the meaning of Canadian securities laws (collectively forward-looking statements). The company cautions that such statements involve risks and uncertainties that may materially affect the companys results of operations. Such forward-looking statements are based on the beliefs of management as well as assumptions made by and information currently available to management. Actual results could differ materially from those contemplated by the forward-looking statements as a result of certain factors, including but not limited to the ability to establish that potential products are efficacious or safe in preclinical or clinical trials; the ability to establish or ...
This release may contain forward-looking statements. Forward-looking statements are all statements other than statements of historical fact. Statements contained in this release that are not historical facts may be deemed to be forward-looking statements. The words anticipate, may, can, plans, believes, estimates, expects, projects, targets, intends, likely, will, should, to be, potential and any similar expressions are intended to identify those assertions as forward-looking statements.. Investors are cautioned that forward-looking statements are inherently uncertain. Actual performance and results may differ materially from that projected or suggested herein due to certain risks and uncertainties. In evaluating forward-looking statements, you should consider the various factors which may cause actual results to differ materially from any forward-looking statements including those listed in the Risk Factors section of our latest 10-K report. Further, the Company ...
This press release includes forward-looking statements and forward-looking information within the meaning of United States securities laws, including statements regarding CytoDyns current and proposed trials and studies and their results, costs and completion. These statements and information represent CytoDyns intentions, plans, expectations, and beliefs and are subject to risks, uncertainties and other factors, many beyond CytoDyns control. These factors could cause actual results to differ materially from such forward-looking statements or information. The words believe, estimate, expect, intend, attempt, anticipate, foresee, plan, and similar expressions and variations thereof identify certain of such forward-looking statements or forward-looking information, which speak only as of the date on which they are made.. CytoDyn disclaims any intention or obligation to publicly update or revise any forward-looking statements or forward-looking information, whether as a result of ...
Certain statements in this website may constitute forward-looking statements as defined in Section 27A of the Securities Act of 1933, as amended (the Securities Act), Section 21E of the Securities Exchange Act of 1934 (the Exchange Act), the Private Securities Litigation Reform Act of 1995 (the PSLRA) or in releases made by the Securities and Exchange Commission (SEC), all as may be amended from time to time. Such forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause the actual results, performance or achievements of GBS, Inc. and its affiliates (GBS) or industry results, to differ materially from any future results, performance or achievements expressed or implied by such forward-looking statements. Statements that are not historical fact are forward-looking statements. Forward-looking statements can be identified by, among other things, the use of forward-looking language, such as the words plan, believe, ...
This press release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, with respect to CNBs financial condition, liquidity, results of operations, future performance and business. These forward-looking statements are intended to be covered by the safe harbor for forward-looking statements provided by the Private Securities Litigation Reform Act of 1995. Forward-looking statements are those that are not historical facts. Forward-looking statements include statements with respect to beliefs, plans, objectives, goals, expectations, anticipations, estimates and intentions that are subject to significant risks and uncertainties and are subject to change based on various factors (some of which are beyond CNBs control). Forward-looking statements often include the words believes, expects, anticipates, estimates, forecasts, intends, plans, targets, ...
This site may contain statements, estimates or projections that constitute forward-looking statements as defined under U.S. federal securities laws. These forward-looking statements generally can be identified by the context of the statement or the use of forward-looking terminology, such as believes, estimates, anticipates, intends, expects, plans, is confident that or words of similar meaning. Similarly, statements that describe AECOMs future operating performance, financial results, financial position, plans, objectives, strategies or goals are forward-looking statements. These forward-looking statements are based on AECOMs current expectations. Known and unknown internal and external risks and uncertainties may cause the actual results to be materially different from those expressed in or implied by the forward-looking statements. Such risks and uncertainties include, but are not limited to, the risk factors noted in AECOMs filings with the Securities and Exchange ...
This news release contains forward-looking statements, which are based on managements expectations and are subject to uncertainties and changes in circumstances. Words and expressions reflecting something other than historical fact are intended to identify forward-looking statements, and these statements may include terminology such as may, will, should, expect, plan, anticipate, believe, estimate, future, predict, potential, intend, or continue, and similar expressions. We base our forward-looking statements on our current expectations and projections about future events or future financial performance. Our forward-looking statements are subject to known and unknown risks, uncertainties and assumptions about ETC and its subsidiaries that may cause actual results to be materially different from any future results implied by these forward-looking statements. We caution you not to place undue reliance on these forward-looking statements. ...
This news release contains forward-looking statements, which are based on managements expectations and are subject to uncertainties and changes in circumstances. Words and expressions reflecting something other than historical fact are intended to identify forward-looking statements, and these statements may include terminology such as may, will, should, expect, plan, anticipate, believe, estimate, future, predict, potential, intend, or continue, and similar expressions. We base our forward-looking statements on our current expectations and projections about future events or future financial performance. Our forward-looking statements are subject to known and unknown risks, uncertainties and assumptions about ETC and its subsidiaries that may cause actual results to be materially different from any future results implied by these forward-looking statements. We caution you not to place undue reliance on these forward-looking statements. ...
Sanofi Forward-Looking Statements. This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words expects, anticipates, believes, intends, estimates, plans and similar expressions. Although Sanofis management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond ...
These statements constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words anticipate, believe, estimate, expect, intend, may, plan, predict, project, target, potential, will, would, could, should, possible, continue and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release, and we undertake no obligation to update any forward-looking statement except as required by law. These forward-looking statements are based on estimates and assumptions by our management that, although believed to be reasonable, are inherently uncertain and subject to a number of risks. The following represent some, but not ...
This press release contains statements that are not historical fact and constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements can be identified by words like believes, expects, anticipates, intends, plans, estimates, may, will, would, could, should, potential, target, depends, or similar expressions, or discussions of strategies, plans or intentions. These forward-looking statements represent our estimates and assumptions only as of the date of this news release. We assume no obligation to update or revise any forward-looking statement as a result of new information, future events or other factors. Forward-looking statements are not guarantees of performance. They involve risks, uncertainties and assumptions. Future results may differ materially from those expressed in the forward-looking statements. Forward-looking statements are necessarily based upon various assumptions involving judgments ...
President & CEO. This news release contains forward-looking information within the meaning of applicable Canadian securities legislation. Generally, forward-looking information can be identified by the use of forward-looking terminology such as anticipate, believe, plan, expect, intend, estimate, forecast, project, budget, schedule, may, will, could, might, should or variations of such words or similar words or expressions. Forward-looking information is based on reasonable assumptions that have been made by Mission Ready Services Inc. as at the date of such information and is subject to known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, performance or achievements of Mission Ready Services Inc. to be materially different from those expressed or implied by such forward-looking information.. Forward-looking statements are based on assumptions management believes to be reasonable. Although Mission Ready ...
Email: [email protected] CAUTIONARY STATEMENT ON FORWARD-LOOKING INFORMATION. Certain information contained or incorporated by reference in this Fourth Quarter and Year-End Report 2014, including any information as to our strategy, projects, plans or future financial or operating performance, constitutes forward-looking statements. All statements, other than statements of historical fact, are forward-looking statements. The words believe, expect, anticipate, contemplate, target, plan, intend, continue, budget, estimate, may, will, schedule and similar expressions identify forward-looking statements. Forward-looking statements are necessarily based upon a number of estimates and assumptions that, while considered reasonable by the company, are inherently subject to significant business, economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forward-looking ...
If one or more of the factors affecting the Companys forward-looking information and statements renders forward-looking information or statements incorrect, the Companys actual results, performance or achievements could differ materially from those expressed in, or implied by, the forward-looking information and statements. Therefore, the Company cautions the reader not to place undue reliance on any forward-looking information or statements herein. The effect of these factors is difficult to predict. Factors other than these also could adversely affect the Companys results, and the reader should not consider these factors to be a complete set of all potential risks or uncertainties as new factors emerge from time to time. Management cannot assess the impact of any such factor on the Companys business or the extent to which any factor, or combination of factors, may cause results to differ materially from those contained in any forward-looking statement. Any forward-looking statements only ...
For more information, please visit www.x4pharma.com. Forward-Looking Statements. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. The words may, will, could, would, should, expect, plan, anticipate, intend, believe, estimate, predict, project, potential, continue, target and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Forward-looking statements include, but are not limited to, statements regarding X4s business strategy, including its clinical development plans. These statements are subject to various risks and uncertainties, actual results could differ materially from those projected, and X4 cautions investors not to place undue reliance on the forward-looking statements in this press release. These risks and uncertainties include, without limitation, the risk that ...
Certain statements contained in this press release constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are predictions based on expectations and projections about future events, and are not statements of historical fact. You can identify forward-looking statements by the use of forward-looking terminology such as plan, continue, expect, anticipate, intend, predict, project, estimate, likely, believe, might, seek, may, remain, potential, can, should, could, future and similar expressions, or the negative of those expressions. These forward-looking statements include the Companys beliefs or expectations relating to the Companys expectations relating to the filing of the Form 10-K, the expected timing of its earnings release and conference call and the results of the ongoing review. Such forward-looking statements involve known and unknown risks, uncertainties, and ...
medicines and help patients recover stronger and live longer. Words such as to be, will, commitment, potential, plan, mission, or other similar expressions identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward-looking. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements are based upon Exelixis current plans, assumptions, beliefs, expectations, estimates and projections. Forward-looking statements involve risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of these risks and uncertainties, which include, without limitation: risks and uncertainties related to regulatory review and approval processes and Exelixis compliance with applicable legal and regulatory ...
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates regarding the clinical development of and potential marketing approvals for the product. Forward-looking statements are generally identified by the words expects, anticipates, believes, intends, estimates, plans, would be and similar expressions. Although Sanofis management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements, other than statements of historical fact, including statements regarding our plans and prospects regarding ZIKV-VLA1601, and any other statements containing the words believes, expects, anticipates, intends, plans, estimates and similar expressions, are forward-looking statements. These forward-looking statements are based on our current intentions, beliefs and expectations regarding future events. We cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from our expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement. Any forward-looking statement speaks only as of the date of this press release, and, except as ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements, other than statements of historical fact, including statements regarding our plans and prospects regarding ZIKV-VLA1601, and any other statements containing the words believes, expects, anticipates, intends, plans, estimates and similar expressions, are forward-looking statements. These forward-looking statements are based on our current intentions, beliefs and expectations regarding future events. We cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from our expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement. Any forward-looking statement speaks only as of the date of this press release, and, except as ...
IMPORTANT INFORMATION REGARDING FORWARD-LOOKING STATEMENTS. Certain information set out in this news release constitutes forward-looking information. Forward-looking statements are often, but not always, identified by the use of words such as seek, anticipate, plan, continue, estimate, expect, may, will, intend, could, might, should, believe, schedule and similar expressions. Forward-looking statements are based upon the opinions and expectations of management of the Company as at the effective date of such statements and, in certain cases, information received from or disseminated by third parties. Although the Company believes that the expectations reflected in such forward-looking statements are based upon reasonable assumptions and that information received from or disseminated by third parties is reliable, it can give no assurance that those expectations will prove to have been correct. Forward-looking statements are subject to certain risks and uncertainties ...
A semi-invasive ultrasound imaging system for imaging biological tissue includes a transesophageal probe or a transnasal, transesophageal probe connected to a two-dimensional ultrasound transducer array, a transmit beamformer, a receive beamformer, and an image generator. The two-dimensional transducer array is disposed on a distal portion of the probes elongated body. The transmit beamformer is connected to the transducer array and is constructed to transmit several ultrasound beams over a selected pattern defined by azimuthal and elevation orientations. The receive beamformer is connected to the transducer array and is constructed to acquire ultrasound data from the echoes reflected over a selected tissue volume. The tissue volume is defined by the azimuthal and elevation orientations and a selected scan range. The receive beamformer is constructed to synthesize image data from the acquired ultrasound data. The image generator is constructed to receive the image data and generate images that
This hand held vibration instrument for gum massage and removal of tartar formation is based on the piezo-electric effect. It comprises a high frequency oscillator which drives a set of piezo-electric wafers acting as transducers. The high frequency oscillator (18) which derives its power from the low voltage secondary of a mains transformer, drives a set of piezoelectric wafers (9,10) attached to the metallic vibrator (3). This extends via a vibration transformer (6), which transforms short sharp amplitudes into greater more gentle vibrations, to a rod (7), at the end of which is a bulb shaped tool (26). A central channel (22) is provided for a cleansing fluid.
Press Release issued Feb 13, 2017: Market Research Hub (MRH) has recently announced the inclusion of a new study to its market intelligence database, which is entitled as Label-free Array Systems Market- Global Industry Analysis 2016-2024. The report analyzes the global market with an in-depth investigation of some of the major regions including North America, Asia-Pacific, Latin America, Europe and Middle East & Africa. Moreover, this report studies the current scenario as well as the future market potential for label-free array systems globally.
Phone: 1-888-593-8995. Forward-Looking Information. Certain information presented in this news release may constitute forward-looking information within the meaning of applicable securities laws regarding MINDCURE and its business. Forward-looking information inherently entails known and unknown risks and uncertainties about the future and actual results, performance or achievements contemplated by forward-looking statements made may be materially different from the results anticipated or implied by such forward-looking information. Forward-looking information generally can be identified by the use of terms and phrases such as anticipate, believe, could, estimate, expect, feel, intend, may, plan, predict, project, subject to, will, would, and similar terms and phrases. Some of the specific forward-looking information in this news release includes, but is not limited to, statements with respect to: the companys ability to successfully develop, manufacture and ...
The radiation pattern of shaded single element piezoelectric transducers and transducer arrays has reduced side lobe levels. Shading to reduce the intensity of emitted ultrasound at the edges of the transducer relative to the center is realized by varying the electric/acoustic conversion efficiency or polarization of the piezoelectric material, by having different mechanical element lengths, by selectively poling the piezoelectric material to produce poled and unpoled regions, and by control of electrode geometry. The shading of a phased array ultrasonic transducer is described in both lateral dimensions.
Pressure transducers are transducers that convers pressure into an analog electrical signal. Pressure transducers are devices used to control pressure systems as for instance in air pressure installation. Besides, pressure transducers can be also used to control pressure in boilers and direct them by means of a control system. Pressure transducers can be connected to any control system due to their ability to emit a standard signal so customers can use pressure transducers for many different applications.
The reproduction number R and the growth rate r are critical epidemiological quantities. They are linked by generation intervals, the time between infection and onward transmission. Because generation intervals are difficult to observe, epidemiologists often substitute serial intervals, the time between symptom onset in successive links in a transmission chain. Recent studies suggest that such substitution biases estimates of R based on r. Here we explore how these intervals vary over the course of an epidemic, and the implications for R estimation. Forward-looking serial intervals, measuring time forward from symptom onset of an infector, correctly describe the renewal process of symptomatic cases and therefore reliably link R with r. In contrast, backward-looking intervals, which measure time backward, and intrinsic intervals, which neglect population-level dynamics, give incorrect R estimates. Forward-looking intervals are affected both by epidemic dynamics and by censoring, changing in ...
Statements in this press release that are not statements of historical or current fact constitute forward-looking statements within the meaning of the U.S. securities laws and Canadian securities laws. Such forward-looking statements involve known and unknown risks, uncertainties, and other unknown factors that could cause the actual results of Neptune to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. In addition to statements which explicitly describe such risks and uncertainties, readers are urged to consider statements labeled with the terms believes, belief, expects, intends, projects, anticipates, will, should, likely or plans to be uncertain and forward-looking. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release.. The forward-looking statements contained in this press release are expressly ...
Statements in this press release that are not statements of historical or current fact constitute forward-looking statements within the meaning of the U.S. securities laws and Canadian securities laws. Such forward-looking statements involve known and unknown risks, uncertainties, and other unknown factors that could cause the actual results of Neptune to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. In addition to statements which explicitly describe such risks and uncertainties, readers are urged to consider statements labeled with the terms believes, belief, expects, intends, projects, anticipates, will, should or plans to be uncertain and forward-looking. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release.. The forward-looking statements contained in this press release are expressly qualified in ...
Certain information on this Site contains certain forward-looking statements, which are subject to risks and uncertainties and speak only as of the date on which they are made. The words believe, estimate, expect, target, intend, may, plan or similar expressions are intended to identify forward-looking statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date on which they are made. GWG Holdings undertakes no obligation to update publicly or revise any forward-looking statements. Actual results may differ materially from the expectations disclosed in the forward-looking statements made. Important factors that could cause actual results to differ materially from the companys forward-looking statements are described in GWG Holdings periodic reports, including the Annual Report on Form 10-K, quarterly reports on Form 10-Q and other reports filed with the Securities and Exchange Commission. Please click here to ...
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. Therapeutic Ultrasound Devices Market is expected to witness growth of international market with respect to advancements and innovations including development history, competitive analysis and regional development forecast.. The report starts with a basic Therapeutic Ultrasound Devices market overview. In this introductory section, the research report incorporates analysis of definitions, classifications, applications and industry chain structure. Besides this, the report also consists of development trends, competitive landscape analysis, and key regions development status.. Browse Detailed TOC, Tables, Figures, Charts and Companies Mentioned in Therapeutic Ultrasound Devices Market Research [email protected] https://www.360marketupdates.com/europe-therapeutic-ultrasound-devices-market-report-2017-10462799. Therapeutic Ultrasound Devices Market Key Players Analysis:. ...
Experience the amazing image quality delivered by the Vevo MD high frequency ultrasound system. View clinical ultrasound image examples.
This communication contains forward-looking statements within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In this context, forward-looking statements often address expected future business and financial performance and financial condition, and often contain words such as expect, anticipate, intend, plan, believe, seek, see, will, would, target, similar expressions, and variations or negatives of these words. Forward-looking statements by their nature address matters that are, to different degrees, uncertain, such as statements about the consummation of the proposed transaction and the anticipated benefits thereof. Forward-looking statements are not guarantees of future performance and are based on certain assumptions and expectations of future events which may not be realized. Forward-looking statements also involve risks and uncertainties, ...
ReSolve Asset Management Inc. (ReSolve). is registered as an investment fund manager in Ontario and Newfoundland and Labrador, and as a portfolio manager and exempt market dealer in Ontario, Alberta, British Columbia and Newfoundland and Labrador. In the U.S. ReSolve is registered with the United States Securities and Exchange Commission as a Non-Resident Investment Adviser.. Forward-Looking Information. The contents hereof may contain forward-looking information within the meaning of the Securities Act (Ontario) and equivalent legislation in other provinces and territories. Because such forward-looking information involves risks and uncertainties, actual performance results may differ materially from any expectations, projections or predictions made or implicated in such forward-looking information. Prospective investors are therefore cautioned not to place undue reliance on such forward-looking statements. In addition, in considering any prior performance information contained herein, ...
In some cases, forward-looking statements can be identified by terminology such as will, may, should, could, expects, intends, plans, aims, anticipates, believes, estimates, predicts, potential, continue, or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Modernas control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others: the fact that there has never been a commercial product utilizing mRNA technology approved for use; the fact that the rapid response technology in use by ...
This press release contains forward-looking statements about ORIC as that term is defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, statements regarding ORICs development plans; the ability of ORIC-101 to overcome resistance in cancer models; plans underlying ORIC-101 clinical trials and development; plans to report interim data from the two ongoing clinical trials of ORIC-101; and the potential advantages of ORICs product candidates. Words such as believes, anticipates, plans, expects, intends, will, goal, potential and similar expressions are intended to identify forward-looking statements. The forward-looking statements contained herein are based upon ORICs current expectations and involve assumptions that may never materialize or may prove to be incorrect. ...
Air-coupled ultrasonic techniques are being increasingly used for material characterization, non-destructive evaluation of composite materials using guided waves as well as for distance measurements. Application of those techniques is mainly limited by the big losses of ultrasonic signals due to attenuation and mismatch of the acoustic impedances of ultrasonic transducers and air. One of the ways to solve this problem is by application of novel more efficient piezoelectric materials like lead magnesium niobate-lead titanate (PMN-PT) type crystals. The objective of this research was the development and investigation of low frequency (<50 kHz) wide band air-coupled ultrasonic transducers and arrays with an improved performance using PMN-32%PT crystals. Results of finite element modelling and experimental investigations of the developed transducers and arrays are presented. For improvement of the performance strip-like matching elements made of low acoustic impedance, materials such as polystyrene foams
Discover Vevo® MD, the worlds first Ultra High Frequency ultrasound system for clinical use. Vevo® MD delivers the highest resolution possible in medical ultrasound when imaging the first 3cm of the body.
Cool new(er) technology might speed the time it takes to perform catheter ablation of atrial fibrillation: the high frequency ultrasound balloon. It has a fluid-filled inner chamber and an outer carbon dioxide-filled balloon that helps focus the ultrasound in a ring-like pattern in an attempt to ablate (or burn) around the pulmonary veins in the left atrium (the site where its thought the atrial fibrillation comes from). Average lesion time takes 40-90 seconds and it covers LOTS of territory in the left atrium. Its just starting clinical trials.... Seems promising. Well see ...
High Frequency Ultrasound Coagulating Cutter Market Research is expecting to accrue strong growth in forecasts frame, drive By Type, End User.
You are at: Home » Products » Disabilities » Ozone High Frequency Ultrasound / Ultrasonic Facia In total 213268 number ofProductsinfo,Released today. 0 number of ...
In this study, we will deploy annular-array systems and assess their experimental and clinical utility for ophthalmic imaging. We hypothesize that a 20-MHz annular array will detect posterior vitreous detachment (PVD) more reliably than a conventional single element ultrasound system. Clinically, we will test the hypothesis that 20-MHz annular arrays improve detection of PVD, an important risk factor for disease progression in diabetic retinopathy. Diabetic retinopathy is the leading cause of blindness in the working population (25 to 65 years) and the third major cause of legal blindness in the U.S.. We propose to carry out a study of 30 human subjects, aged 60 years or above, in whom PVD is likely to be present as a consequence of normal aging. The study will compare the ability to detect PVD using a commercial ophthalmic ultrasound system equipped with 10- and 20-MHz sector scan probes (Cinescan A/B-S, Quantel Medical), and OCT (OCT/SLO, Ophthalmic Technologies, Inc.), and the 20-MHz annular ...
0037] The present invention relates to an ultrasound coupling device suitable for use with low-profile ultrasound transducers and systems. The ultrasound coupling device of the present invention is particularly suitable for use with portable ultrasound devices, systems, and methods. Further, the ultrasound coupling device of the present invention can be configured to be either disposable or re-useable, and can be used with ultrasound transducers that are either disposable or re-usable. Therefore, in one aspect, the present invention provides an entirely autonomous ultrasound coupling device for use with portable ultrasound transducers and systems. In addition, the ultrasound coupling device of the present invention can be configured so as to enable the generation of ultrasonic energy from an ultrasound transducer or system. In this configuration, the ultrasound coupling device is configured so that ultrasonic energy is only transmitted when the ultrasound transducer is properly coupled with the ...
expected network coverage to new markets, expected expansion of 4G LTE bandwidth and the expected timing of closing the transaction, are forward-looking statements. Generally, forward-looking statements may be identified by words such as anticipate, expect, suggests, plan, believe, intend, estimates, targets, views, may, will, forecast, and other similar expressions. The forward-looking statements speak only as of the date made, are based on current assumptions and expectations, and involve a number of risks and uncertainties. Important factors that could affect future results and cause those results to differ materially from those expressed in the forward-looking statements include, among others, the following: adverse conditions in the U.S. and international economies and markets; our ability to successfully integrate the MetroPCS and ...
Item 2. Management s Discussion and Analysis of Financial Condition and Results of Operations The following discussion and analysis of our financial condition and results of operations should be read in conjunction with our condensed financial statements and related notes appearing elsewhere in this Quarterly Report on Form 10-Q and our annual report on Form 10-K dated December 31, 2014. Forward-Looking Statements This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act). These forward-looking statements are based on our management s belief and assumptions and on information currently available to management. Although we believe that the expectations reflected in these forward-looking statements are reasonable, these statements relate to future events, including our clinical development plans, or our future financial performance and involve ...
Statements in articles on this blog other than purely historical information, historical estimates should not be relied upon, including statements relating to the companies future plans and objectives or expected results, are forward-looking statements. News releases contain certain Forward-Looking Statements within the meaning of Section 21E of the United States Securities Exchange Act of 1934, as amended. Forward-looking statements are based on numerous assumptions and are subject to all of the risks and uncertainties inherent in the companies business, including risks inherent in resource exploration and development. As a result, actual results may vary materially from those described in the forward-looking statements ...
This release contains forward-looking statements regarding our strategy, future plans and prospects, including statements regarding the development of the companys product candidates, the potential safety and efficacy profile of roxadustat, the potential for our Phase 3 program data to form the basis of a regulatory approval, our clinical and regulatory plans, and those of our partners. These forward-looking statements include, but are not limited to, statements about our plans, objectives, representations and contentions and are not historical facts and typically are identified by use of terms such as may, will, should, on track, could, expect, plan, anticipate, believe, estimate, predict, potential, continue and similar words, although some forward-looking statements are expressed differently. Our actual results may differ materially from those indicated in these forward-looking statements due to risks and uncertainties related to the continued progress and timing of ...
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are subject to risks, uncertainties and other factors, including the risk that Genvoya may not be approved by other regulatory authorities and the marketing applications for F/TAF and/or R/F/TAF may not be approved by the EMA, and marketing approvals, if granted, may have significant limitations on their use. These risks, uncertainties and other factors could cause actual results to differ materially from those referred to in the forward-looking statements. The reader is cautioned not to rely on these forward-looking statements. These and other risks are described in detail in Gileads Quarterly Report on Form 10-Q for the quarter ended September 30, 2015, as filed with the U.S. Securities and Exchange Commission. All forward-looking statements are based on information currently available to Gilead, and Gilead assumes no obligation to update any such ...
This press release contains certain forward-looking statements that involve risks, uncertainties and assumptions that are difficult to predict, including statements regarding the Companys upcoming meeting with the FDA to discuss the adequate number and type of evaluable patients required for efficacy and safety necessary to support the filing of a Biologic License Application and our intention to continue enrolling patients in our CD02 combination trial. Words and expressions reflecting optimism, satisfaction or disappointment with current prospects, as well as words such as believes, hopes, intends, estimates, expects, projects, plans, anticipates and variations thereof, or the use of future tense, identify forward-looking statements, but their absence does not mean that a statement is not forward-looking. Our forward-looking statements are not guarantees of performance and actual results could differ materially from those contained in or expressed by such statements. In ...
For additional information, visit avrobio.com, and follow us on Twitter and LinkedIn. Forward-Looking Statement This press release contains forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words and phrases such as aims, anticipates, believes, could, designed to, estimates, expects, forecasts, goal, intends, may, plans, possible, potential, seeks, will, and variations of these words and phrases or similar expressions that are intended to identify forward-looking statements. These forward-looking statements include, without limitation, statements regarding our business strategy for and the potential therapeutic benefits of our prospective product candidates, the design, commencement, enrollment and timing of ongoing or planned clinical trials, clinical trial results, product approvals and regulatory pathways, anticipated ...
This release contains forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements are typically preceded by words such as believes, expects, anticipates, intends, will, may, should, or similar expressions. These forward-looking statements reflect managements current knowledge, assumptions, judgment and expectations regarding future performance or events. Although management believes that the expectations reflected in such statements are reasonable, they give no assurance that such expectations will prove to be correct or that those goals will be achieved, and you should be aware that actual results could differ materially from those contained in the forward-looking statements. Forward-looking statements are subject to a number of risks and uncertainties, including, but not limited to, our ability to successfully complete research and further development and commercialization of Company drug ...
is committed to improving the health of patients with kidney and vascular diseases through the development of novel, first-in-class therapeutics. Proteons lead product candidate, vonapanitase, is an investigational drug intended to improve hemodialysis vascular access outcomes. Proteon is currently enrolling patients in PATENCY-2, a Phase 3 clinical trial evaluating vonapanitase in patients with CKD undergoing surgical creation of a radiocephalic arteriovenous fistula for hemodialysis. Proteon is also evaluating vonapanitase in a Phase 1 clinical trial in patients with PAD. For more information, please visit www.proteontx.com.. Cautionary Note Regarding Forward-Looking Statements. This press release contains statements that are, or may be deemed to be, forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. In some cases, these forward-looking statements can be identified by the use of forward-looking terminology, including the terms estimates, ...
This press release includes forward-looking statements regarding the business of Akcea Therapeutics, Inc. and Ionis Pharmaceuticals, Inc. and the therapeutic and commercial potential of WAYLIVRATM (volanesorsen). Any statement describing Akceas or Ionis goals, expectations, financial or other projections, intentions or beliefs, including the commercial potential of WAYLIVRA or other of Akceas or Ionis drugs in development is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties, particularly those inherent in the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. Akceas and Ionis forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking ...
Forward-Looking Statements Certain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. Such forward-looking statements include statements about the advancement, therapeutic indication and use, safety, efficacy, tolerability, mechanism of action and potential of lorcaserin; the significance of the PWG s re-adjudication and the CSF study, including the potential use of the results; the response to the CRL for the lorcaserin NDA, including related plans, activities and timing; the therapeutic indication of APD811; and Arena s views, focus, goals, strategy, research and development programs, and ability to develop compounds and commercialize drugs. For such statements, Arena claims the protection of the Private Securities Litigation Reform Act of 1995. Actual events or results may differ materially from Arena s expectations. Factors that could cause actual results to differ materially from the forward-looking statements include, but are ...
We offer a variety of servo gearboxes and although they may appear the same, they function differently. Kyle goes through each style of gearbox and when they would be ideal for specific projects.. Channel Gearboxes: Designed to mount inside Actobotics Channel. Great for robotic arms and projects that have limited space. 1/2 output shaft.. Top Flange Gearboxes: Designed to be flush mounted with the tabs protruding from the top plane of the gearbox. Excellent for R/C sailboats. 3/8 output shaft.. Bottom Flange Gearboxes: Designed to be mounted to a flat surface with the bottom flanges. Great for FPV antenna trackers and base gearboxes on robotic arms. 3/8 output shaft.. Square Tube Gearboxes: Sleek, rectangular profile with mounting options on the ends and sides. 1/2 output shaft (1 shaft available on some models).. ...
Piezoelectric materials are utilized for high-power ultrasonic devices such as ultrasonic motors, which are driven under high stress and strain. The nonlinear elastic vibration of piezoelectric materials is a critical problem because it degrades the output performance. (Bi,Na)TiO3-BaTiO3 (BNBT) ceramics are one of the lead-free piezoelectric materials that show outstanding characteristics under high power driving, such as stable mechanical quality factor and resonance frequency. We evaluated the high-power characteristics of BNBT ceramics by measuring complex higher-order elastic constants using a nonlinear piezoelectric vibration model. We found that the absolute value of the higher-order elastic constant of BNBT was less than 4% of Pb(Zr,Ti)O3 (PZT). Additionally, we developed a miniature ultrasonic motor using a BNBT multilayered piezoelectric transducer. This multilayered structure was utilized to enhance the piezoelectric displacement and was equipped with elastic fins, which convert the ...
A device for acquiring data and diagnosing a musculoskeletal injury. The device includes a semi-flexible housing, at least one ultrasonic transducer, a positional localizer, and a transmission system. The semi-flexible housing is positioned proximate a portion of the musculoskeletal system of a patient and supports the at least one ultrasonic transducer and the positional localizer. The at least one ultrasonic transducer is configured to acquire an ultrasonic data indicative of a bone surface. The positional localizer is positioned at a select location relative to the at least one ultrasonic transducer and tracks movement of the housing. The transmission system transmits the ultrasonic data of the at least one ultrasonic transducer and the movement data of the positional localizer to a data analyzer for analysis and diagnosis.
At O-I Glass, Inc. (NYSE: OI), we love glass and were proud to make more of it than any other glass bottle or jar producer in the world. We love that its beautiful, pure and completely recyclable. With global headquarters in Perrysburg, Ohio, we are the preferred partner for many of the worlds leading food and beverage brands. Working hand and hand with our customers, we give our passion and expertise to make their bottles iconic and help build their brands around the world. With more than 26,500 people at 78 plants in 23 countries, O-I Glass has a global impact, achieving revenues of $6.9 billion in 2018. For more information, visit o-i.com.. Forward-Looking Statements. This press release contains forward-looking statements related to O-I Glass, Inc. (O-I Glass or the Company) within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act) and Section 27A of the Securities Act of 1933. These forward-looking statements relate to a variety of ...
This press release contains forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about ADMA Biologics, Inc. (we, our or the Company). Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate, or imply future results, performance or achievements, and may contain the words estimate, project, intend, forecast, target, anticipate, plan, planning, expect, believe, will, is likely, will likely, should, could, would, may, or, in each case, their negative, or words or expressions of similar meaning. These forward-looking statements also include, but are not limited to, statements concerning our plans to develop, manufacture, market, launch and expand our own commercial infrastructure and commercialize our current products and future products, the safety, efficacy and expected timing of, and our ability to, obtain and maintain regulatory ...
This press release contains forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about ADMA Biologics, Inc. (we, our or the Company). Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate, or imply future results, performance or achievements, and may contain the words estimate, project, intend, forecast, target, anticipate, plan, planning, expect, believe, will, is likely, will likely, should, could, would, may, or, in each case, their negative, or words or expressions of similar meaning. These forward-looking statements also include, but are not limited to, statements concerning our plans to develop, manufacture, market, launch and expand our own commercial infrastructure and commercialize our current products and future products, the safety, efficacy and expected timing of, and our ability to, obtain and maintain regulatory ...
First Majestic is a mining company focused on silver production in México and is aggressively pursuing the development of its existing mineral property assets and the pursuit through acquisition of additional mineral assets which contribute to the Company achieving its corporate growth objectives.. FIRST MAJESTIC SILVER CORP.. Keith Neumeyer, President & CEO Cautionary Note Regarding Forward-Looking Statements. This press release contains forward-looking statements, within the meaning of the United States Private Securities Litigation Reform Act of 1995 and applicable Canadian securities legislation, concerning the business, operations and financial performance and condition of First Majestic Silver Corp. Forward-looking statements include, but are not limited to, statements with respect to the future price of silver and other metals, the estimation of mineral reserves and resources, the realization of mineral reserve estimates, the timing and amount of estimated future production, costs of ...
Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping, and pre-clinical nucleic acid-based therapeutic drug candidates. Applied DNA makes life real and safe by providing innovative, molecular-based technology solutions and services that can help protect products, brands, entire supply chains, and intellectual property of companies, governments and consumers from theft, counterfeiting, fraud and diversion. Visit adnas.com for more information. Follow us on Twitter and LinkedIn. Join our mailing list. Common stock listed on NASDAQ under the symbol APDN, and warrants are listed under the symbol APDNW. Forward-Looking Statements The statements made by Applied DNA in this press release may be forward-looking in nature within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe Applied DNAs future plans, projections, strategies and expectations, and ...
This news release may contain certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. These statements are based on managements current expectations and are subject to uncertainty and changes in circumstances. Actual results may vary materially from the expectations contained in the forward-looking statements. The following factors, among others, could cause actual results to differ materially from those described in any forward-looking statements: competitive pressures; the loss of one or more key customer or supplier relationships; customer defaults or insolvencies; changes in customer mix; supplier defaults or insolvencies; changes in pharmaceutical manufacturers pricing and distribution policies or practices; adverse resolution of any contract or other disputes with customers (including departments and agencies of the U.S. Government) or suppliers; regulatory changes (including increased ...
This press release contains forward-looking statements, including statements that relate to, among other things, revenue forecasts, technology development progress, plans for shipment using the Companys technology, production plans, the Companys markets, objectives, goals, strategies, intentions, beliefs, expectations and estimates, and can generally be identified by the use of words such as may, will, could, should, would, likely, possible, expect, intend, estimate, anticipate, believe, plan, objective and continue (or the negative thereof) and words and expressions of similar import. Although the Company believes that the expectations reflected in such forward-looking statements are reasonable, such statements involve risks and uncertainties, and undue reliance should not be placed on such statements. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied ...
... (MET) are a class of inertial sensors (which include accelerometers, gyroscopes, tilt meters, ... vol.31, p. 474 (1959). C. W. Larkam, "Theoretical Analysis of the Solion Polarized Cathode Acoustic Linear Transducer", J. ... meters Seismic sensors Seismometers Angular accelerometers Angular rate sensors Gyroscopes Tiltmeters Pressure transducers "MET ...
The volume near the transducer which exhibits this phenomenon is called the near field, as opposed to the far field where wave ... Acoustic waves emitted by ultrasonics transducer crystals exhibit a property known as self-focusing (or natural focusing). Note ... Dreyer, T.; Krauss, W.; Bauer, E. & Riedlinger, R.E. (October 2000). "Investigations of compact self focusing transducers using ... from the electronically controlled focusing employed in diagnostic ultrasound devices which employ arrays of transducers. The ...
A transducer is a device that converts energy from one form to another. Usually a transducer converts a signal in one form of ... Noise: All transducers add some random noise to their output. In electrical transducers this may be electrical noise due to ... Transducers can be categorized by which direction information passes through them: A sensor is a transducer that receives and ... Transducers with larger dynamic range are more "sensitive" and precise. Repeatability: This is the ability of the transducer to ...
The beam pattern of a transducer can be determined by the active transducer area and shape, the ultrasound wavelength, and the ... Ultrasonics, typically refers to piezoelectric transducers or capacitive transducers. Piezoelectric crystals change the size ... The transducer may be used in contact with the skin, as in fetal ultrasound imaging, or inserted into a body opening such as ... An ultrasonic transducer is affixed to a stainless steel pan which is filled with a solvent (frequently water or isopropanol). ...
The domain of a transducer is the domain of its semantics. Likewise, the image of a transducer is the image of its semantics. ... Roughly speaking, tree transducers extend tree automata in the same way that word transducers extend word automata. ... The main classes of tree transducers are: A TOP T is a tuple (Q, Σ, Γ, I, δ) such that: Q is a finite set, the set of states; Σ ... Consider the transducer coding the transformation f ( x ) → g ( x , x ) {\displaystyle f(x)\to g(x,x)} ; that is, duplicate the ...
If the transducer's processor is not able to respond, the bus will remain high during the read. If the transducer's processor ... enables the transducer to transmit important data to the echosounder, including transducer model, functions, frequency, power ... "Transducer wiring diagrams". 2019-06-28. Archived from the original on 2019-06-18. "Wiring Diagrams for CHIRP Transducers". ... US 2005259517, "Transducer identification", issued 2005-11-24 "Airmar Transducer ID Press Release" (PDF). Airmar Technology ...
... an input transducer). The same principle is applied to the conversion of SAW back to electric signals (an output transducer). ... An interdigital transducer (IDT) is a device that consists of two interlocking comb-shaped arrays of metallic electrodes (in ... Mamishev, A.V.; Sundara-Rajan, K.; Yang, F.; Du, Y.; Zahn, M. (2004). "Interdigital sensors and transducers" (PDF). Proceedings ... Transducers, Microtechnology, All stub articles, Electronics stubs). ...
A smart transducer is an analog or digital transducer, actuator or sensor combined with a processing unit and a communication ... "Time-triggered smart transducer networks" (PDF). IEEE Transactions on Industrial Informatics. 2 (3): 192-199. arXiv:1507.04394 ... computing IEEE 1451 Internet of things Intelligent sensor Machine to machine Sentroller SensorML System on a chip Transducer ...
A wind transducer is a device used by sailors to receive a real-time measurement of wind speed and direction. A wind transducer ... Wind transducers are usually wired to the cock or head, although 'wireless' versions are becoming steadily more popular due to ... Articles with short description, Short description matches Wikidata, Transducers, Sailing equipment). ...
Tactile transducers may augment or in some cases substitute for a subwoofer. One benefit of tactile transducers is they produce ... A tactile transducer or "bass shaker" is a device which is made on the principle that low bass frequencies can be felt as well ... Tactile transducers may be used in a home theater, a video gaming chair or controller, a commercial movie theater, or for ... For example, mounting a tactile sound transducer in a chair or couch in a home cinema or video game setup can give more of a ...
An ortho-mode transducer can be modelled as a 4-port device, 2 of these (H and V) representing the single-polarization ports ... An orthomode transducer (OMT) is a waveguide component that is commonly referred to as a polarisation duplexer. Orthomode is a ... On each dish a T-shaped ortho-mode transducer is mounted at the rear of the feed, separating the signal from the feed into two ... An ortho-mode transducer is also a component commonly found on high capacity terrestrial microwave radio links. In this ...
A log space transducer, M {\displaystyle M} , has three tapes: A read-only input tape. A read/write work tape (bounded to at ... In computational complexity theory, a log space transducer (LST) is a type of Turing machine used for log-space reductions. ...
Given a transducer T on alphabets Σ and Γ and a transducer S on alphabets Γ and Δ, there exists a transducer T ∘ S {\ ... Given transducers T and S, there exists a transducer T ∪ S {\displaystyle T\cup S} such that x [ T ∪ S ] y {\displaystyle x[T\ ... Given transducers T and S, there exists a transducer T ⋅ S {\displaystyle T\cdot S} such that x [ T ⋅ S ] y {\displaystyle x[T\ ... Given a transducer T, we want to build an equivalent transducer that has a unique initial state and such that no two ...
EMAT transducers typically produce raw signal of lower power than piezoelectric transducers. As a result, more sophisticated ... Electromagnetic acoustic transducer (EMAT) is a transducer for non-contact acoustic wave generation and reception in conducting ... Although there are EMAT transducers as small as a penny, commonly used transducers are large in size. Low-profile EMAT problems ... the relative position between the transducer and the test part, and the excitation signal for the transducer. The spatial ...
The piezoelectrochemical transducer effect (PECT) is a coupling between the electrochemical potential and the mechanical strain ... p. 3. Kading, Glen (2007). Piezo-Electrochemical Transducer Effect (PECT) Intercalated Graphite Micro-Electrochemical Actuators ... Kading, Glen (2007). Piezo-Electrochemical Transducer Effect (PECT) Intercalated Graphite Micro-Electrochemical Actuators. Ohio ...
An Exciter is an electroacoustic transducer. Exciters differ from the more common loudspeaker in that they have no cone and ...
In a pitch-catch experiment, the transducer is benchmarked using a hydrophone, and in a pulse-echo experiment, the transducer ... Most of the commercial ultrasonic transducers today are based on piezoelectricity. CMUTs are the transducers where the energy ... A capacitive micromachined ultrasonic transducer (CMUT) is a relatively new concept in the field of ultrasonic transducers. ... The properties to use in high frequency with large bandwidth makes it a good choice to use as a transducer in medical imaging, ...
... (TACSTD) is the name of two human proteins and the genes that encode them: Tumor- ... associated calcium signal transducer 1 (Epithelial cell adhesion molecule, EpCAM) Tumor-associated calcium signal transducer 2 ... This disambiguation page lists articles associated with the title Tumor-associated calcium signal transducer. If an internal ...
The HART Communication Protocol (Highway Addressable Remote Transducer) is a hybrid analog+digital industrial automation open ...
Transducers were added as a method for composing transformations. Transducers enable higher-order functions such as map and ... Hickey, Rich (2014-09-17). "Transducers". YouTube.com. Hickey, Rich (2014-08-06). "Transducers are Coming". Cognitect.com. ... While traditionally these functions operate on sequences, transducers allow them to work on channels and let the user define ... Hickey, Rich (2014-11-20). "Inside Transducers". YouTube.com. "Official EDN Spec". edn-format.org. 2022-04-27. "ClojureScript ...
TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519. Farrens, S.; Sood, S. (2008). "Wafer Level ...
Micromachined ultrasound transducers. MEMS-based loudspeakers focusing on applications such as in-ear headphones and hearing ... TRANSDUCERS '05. Vol. 2. IEEE. pp. 1118-1121. doi:10.1109/SENSOR.2005.1497272. ISBN 9780780389946. S2CID 28068644. Bustillo JM ... Hajati A (2012). "Three-dimensional micro electromechanical system piezoelectric ultrasound transducer". Appl. Phys. Lett. 101 ... Transducers, Mechanical engineering, Electrical engineering, Microtechnology, Microelectronic and microelectromechanical ...
Piezoelectric Micromachined Ultrasonic Transducers (PMUT) are MEMS-based piezoelectric ultrasonic transducers. Unlike bulk ... In comparison with bulk piezoelectric ultrasound transducers, PMUT can offer advantages such as increased bandwidth, flexible ... Muralt, Paul (December 2005). "Piezoelectric micromachined ultrasonic transducers based on PZT thin films". IEEE Trans ... Brown, Lewis (November 2000). "Design Considerations for Piezoelectric Polymer Ultrasound Transducer". IEEE Trans Ultrasonics, ...
This method works with an ultrasonic transducer scanning the wafer bond. The reflected sound signal is used for the image ... TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519. Sood, S.; Thomas, R.; Adams, T. (2008). " ... Deionized water is used as the acoustic interconnect medium between the electromagnetic acoustic transducer and the wafer. ...
TRANSDUCERS 2009. International. pp. 244-247. doi:10.1109/SENSOR.2009.5285519.{{cite conference}}: CS1 maint: multiple names: ...
Piezoceramic transducers of physical sizes.- Cherkasy: ChGTU, 2005.- 631p. Sharapov V.M. et al. Automatic control theory. ... Piezoelectric transducers. The handbook. - Cherkasy: ChGTU, 2004. - 435 p. Sharapov V.M. et al. Programmed logic controllers in ... 240 p. ISBN 9781873082096 Sharapov V.М., Minaev I.G., Sotula Zh.V., Kunitskaya L.G. Electroacoustic Transducers. - Moscow: ... Sharapov V.M., Sotula Zh.V., Kunitskaya L.G. Piezoelectric electroacoustic transducers. - Cherkasy: Vertical, 2012.-255p. ...
"Passive Radiators". Geddes, Earl; Lee, Lidia W. (2002). Acoustic Transducers. United States: GedLee. ISBN 978-0972208505. ...
The unit consists of a hollow tube that is sealed by a piezoelectric transducer on each end. The transducers are oppositely ... Finally the outputs of the individual transducers are measured, the residual voltage difference is tabulated, and the dominate ... Accelerometers based upon piezoelectricity are constructed with two piezoelectric transducers. ... As with all transducers, piezoelectric convert one form of energy into another and provide an electrical signal in response to ...
Resistive components, Transducers). ...
Magnetic ordering, Transducers). ...
With depth, speed and temp sensors in a single package, the P58 is an ideal transom mount transducer for small vessels. ... P58 Transom Mount Transducer. Urethane, 600W, Dual Frequency (50/200 kHz) for CP370 Sonar ... P58 can be adapted to work with other systems using optional transducer adapter cables, sold separately. ...
These two-wire transducers use moving-coil technology to provide a voltage output that is directly proportional to the ... Moving-coil transducers are less sensitive to impact excitation than integrating accelerometers and can be appropriate for ... Our Seismoprobe Velocity Transducer Systems measure bearing housing, casing and structural vibration. ...
Encoders and Transducers. Electrical encoders and transducers, such as shaft encoders and LEDs ... Sensors and Transducers. Analog and digital sensors, such as proximity sensors, current and voltage sensors, thermistors, shaft ...
Order today, ships today. SEN0347 - Optical Sensor 4.9 (1.50m) NPN from DFRobot. Pricing and Availability on millions of electronic components from Digi-Key Electronics.
Understanding Transducers. See README below. GitHub Gist: instantly share code, notes, and snippets. ... Understanding Transducers. Understanding transducers by building them from scratch.. Goes along with the blog post ... mapping transducer does (reducing result (f input)). But for. ;; mapcatting, we want to concatenate the collection returned ... For taking transducer. I think the state should not be maintained in the taking fn, but in the fn returned by the taking ...
Mounting Kit mounting pressure transducer GRIMECA semi-hydraulic on steering column (16mm) ... Mounting Kit mounting pressure transducer GRIMECA semi-hydraulic on steering column (16mm) ... Mounting Kit mounting pressure transducer GRIMECA semi-hydraulic on steering column (16mm) ...
ButtKicker PLUS Haptic Transducer. Weight: 2.7 lbs.. Frequency Response: 5-200 Hz. Piston Weight: 6 oz.. Nominal Impedance: 2 ... The haptic transducer is driven by the audio output, so it works instantly with everything: games, movies, music, & streaming. ... 9.8 cables with quick release connecting Gamer PLUS transducer to amplifier. - Mini Y adapters. - 6.5 RCA to mini (3.5mm) ... HaptiConnect can be used with one or more ButtKicker units and works with all models and generations of ButtKicker transducers ...
Radioear B-71 Bone Conduction Transducer Bone Conductor with usb connector ... Radioear B-71 Bone Conduction Transducer Bone Conductor with usb connector For Sale ... Radioear B-71 Bone Conduction Transducer Bone Conductor with usb connector : $100.00. ...
Transducers including the all-in-one SonarHub Sounder Module for CHIRP & StructureScan HD sonar capabilities. ... has changed the landscape of the marine electronics industry with continued sonar and transducer innovation. As sonar ...
... Forward Scan Sonar Avoid Running Aground with Premium FrontV Forward-looking ... Garmin ECHOMAP UHD 73cv US LakeVu g3 with GT24UHD-TM Transducer. Garmin ECHOMAP UHD 73sv US LakeVu g3 without Transducer. ... Garmin ECHOMAP UHD 74cv US Offshore g3 with GT24UHD-TM Transducer. Garmin ECHOMAP UHD 74sv US Offshore g3 without Transducer. ... Garmin ECHOMAP UHD 93sv US LakeVu g3 without Transducer. Garmin ECHOMAP UHD 92sv without Transducer. Garmin ECHOMAP Ultra 102sv ...
Expert Transducers, available in stationary and rotary styles, are designed for use with the Expert EXTA Torque Analyzer or ... Transducers Expert Transducers, available in stationary and rotary styles, are designed for use with Ingersoll Rands Expert ... Smart Transducers include a feature that allows them to self-identify themselves to an Expert EXTA Torque Analyzer for easy set ... Industry Standard Transducers can be used with other manufacturers equipment that conforms to the Industry standard. ...
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We report the development of an optically transparent high-frequency ultrasonic transducer using lithium niobate single-crystal ... The center frequency of the transducer was at 36.9 MHz with 33.9 %, at -6 dB fractional bandwidth. Photoacoustic imaging ... We report the development of an optically transparent high-frequency ultrasonic transducer using lithium niobate single-crystal ... Transparent High-Frequency Ultrasonic Transducer for Photoacoustic Microscopy Application, IEEE Transactions on Ultrasonics ...
Focus Study of Sensor Characteristics and design of Signal Conditioning circuits. Infrastructure. ...
A fiber quality transducer includes an inlet mixing probe, a rotating valve sleeve, a camera and a sampling cell. Slurry from a ... US7701575B2 - Fiber quality transducer - Google Patents. Fiber quality transducer Download PDF Info. Publication number. ... the fiber quality transducer 1 includes an inlet mixing probe 10, a rotating valve sleeve 12, a base block 14, a camera 16 and ... US11/697,813 2007-04-09 2007-04-09 Fiber quality transducer Expired - Fee Related US7701575B2 (en) Priority Applications (1). ...
... providing a flat transducer / vibration sensor mounting solution for any of our vibration transducers. ...
The 972B-21030 DualMag Cold Cathode Vacuum Transducer offers a measurement range from 1x10-8 Torr to atmospheric pressure and ... All Series 970B transducers have an analog pressure output of 0.5VDC/decade that can be interfaced to external analog equipment ... Vacuum Transducer, Cold Cathode-MicroPirani, NW25 ISO-KF, RS232, 3 Relays. Model: 972B-21030. ... Vacuum Transducer, Cold Cathode-MicroPirani, NW25 ISO-KF, RS232, 3 Relays. Model: 972B-21030. ...
Learn how to distinguish between force sensors and force transducers. ... Force sensors , force transducers. How do force sensors and force transducers differ from one another?. Force sensors or force ... Force transducers, on the other hand, are sensors that are based on the strain gauge principle. They are suitable for the ... Piezoelectric force sensors, force sensors or force transducers measure dynamic and quasistatic forces. There are a number of ...
Tag Archives: transducers ATLAS North America Unveils New Side Scan Sonar System. Posted on 05/06/2020. by Sea Technology ...
Where would I use a Current Transducer?. CTs are used in a wide range of industrial and commercial measurement applications. ... Current transformers or (CT s), also known as Core Balance Current Transformers or Current Transducers, are instruments that ...
Shop Garmin LiveScope XR LVS62 Fishfinder Transducer Only and other name brand Fishing Accessories Sports & Outdoors at The ... LiveScope XR LVS62 transducer. - Perspective mount (LiveScope XR LVS62 transducer only). - Trolling motor barrel mount. - Shaft ... The new XR transducer offers live scanning sonar up to 500 ft. in freshwater and up to 350 ft. in saltwater. Adjust the ... New XR transducer upgrades your system. - Sharp images at short and long range simultaneously. - Live scanning sonar up to 500 ...
Non-imaging transducer Find similar products Learn more about the Philips D2tcd PW non-imaging transducer in the specification ...
Input trigger signal 10us TTL Impulse. Detection distance 2cm~450cm. Sensor angle Not more than 15 degrees. High Quality ETL/CSA/CE/NSF/FCC - We passed every evaluation of pool products, even ASTM which for pool alarm in USA laboratory.
Echomax XPS transducers use ultrasonic technology to measure level in a wide range of liquids and solids. The transducers can ... ST-H transducers use ultrasonic technology to measure level in chemical storage and liquid tanks. The narrow design of the ST-H ... The low-cost XRS-5 transducer is compatible with a full range of Siemens controllers, from a basic system for high/low alarm or ... Siemens Echomax transducers are easy to install and require little to no maintenance, handling dust, moisture, vibrations, ...
Traditional ultrasound transducers are built from bulk piezoelectric materials, in a process that is inefficient and expensive ... High-Performance Handheld Ultrasound Based on Piezoelectric Micromachined Ultrasonic Transducers. August 20th, 2019 Kurt Yaeger ... They also plan to utilize their novel ultrasound transducer technology for enhanced 3D imaging, which may one day be performed ... Therefore, pMUTs are smaller, less expensive to manufacture, and are able to generate higher quality images than transducers ...
AC True RMS Current Transducer feature 0.25 accuracy. - Feb 02, 2006 - American Aerospace Controls, Inc. AAC ... Electrical Sensors / Detectors / Transducers AC True RMS Current Transducer feature 0.25% accuracy.. American Aerospace ... and frequency transducers, now offers an AC current transducer that provides superior accuracy over an extended frequency range ... New AC Current Transducer from American Aerospace Controls Provides Versatility, Accuracy and Durability. Farmingdale, NY, ...
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  • With depth, speed and temp sensors in a single package, the P58 is an ideal transom mount transducer for small vessels. (raymarine.com)
  • Transom Mount Kits Choose the High Speed transom mount transducer for aluminum or wood hull boats. (ultimatepassage.com)
  • Measure signal properties using sensors and transducers. (mathworks.com)
  • How do force sensors and force transducers differ from one another? (kistler.com)
  • Force sensors or force transducers are measurement elements designed for the precise measurement of compression and tensile forces. (kistler.com)
  • Force transducers, on the other hand, are sensors that are based on the strain gauge principle. (kistler.com)
  • Piezoelectric force sensors, force sensors or force transducers measure dynamic and quasistatic forces. (kistler.com)
  • Each of these electronic pressure sensors combines a pressure switch and a pressure transducer. (grainger.com)
  • Transducers are sensors that convert biological signals into electrical analog signals. (adinstruments.com)
  • These transducers are superior to infrared sensors because these ultrasonic transducers or sensors are not affected by smoke, black matter, etc. (hyzerme.com)
  • Input transducers, or sensors are classified as either active or passive. (analog.com)
  • The Panoptix multibeam thru-hull transducer with premium FrontV forward-looking sonar helps you avoid running aground by displaying the bottom ahead of your boat in real time on your chartplotter. (wmjmarine.com)
  • Raymarine RV-300 RealVision 3D Plastic Thru Hull Transducer - A80470RV-300 Plastic All-In-One 0° Thr. (yachtbits.com)
  • Raymarine RV-312 RealVision 3D Plastic Thru Hull Transducer Pack - T70320RV-312 Plastic Through Hull. (yachtbits.com)
  • We report the development of an optically transparent high-frequency ultrasonic transducer using lithium niobate single-crystal and indium-tin-oxide electrodes with up to 90 % optical transmission in the visible to near infrared spectrum. (nist.gov)
  • And for those dirty applications, ultrasonic transducers' self-cleaning faces literally shake themselves clean of dirt and buildup, giving you the reliable performance you need. (siemens.com)
  • Echomax XRS-5 ultrasonic transducer provides reliable, continuous level monitoring of liquids and slurries in narrow lift stations/ wet wells, flumes, weirs and filter beds. (siemens.com)
  • Echomax XPS transducers use ultrasonic technology to measure level in a wide range of liquids and solids. (siemens.com)
  • ST-H transducers use ultrasonic technology to measure level in chemical storage and liquid tanks. (siemens.com)
  • The company EXO Imaging out of Redwood City, CA recently emerged from stealth mode to announce the development of a novel technology called Piezoelectric Micromachined Ultrasonic Transducers (pMUT) for ultrasound imaging. (medgadget.com)
  • What are Ultrasonic Transducers And How Do They Work? (hyzerme.com)
  • An ultrasonic transducer can be defined as a transducer used to convert a type of energy into ultrasonic vibrations. (hyzerme.com)
  • Through these ultrasonic vibrations, the transducer measures the distance of the object. (hyzerme.com)
  • In this article, we'll be discussing what ultrasonic transducers are and how it works. (hyzerme.com)
  • What are ultrasonic transducers? (hyzerme.com)
  • An ultrasonic transducer is a sound-related sensor. (hyzerme.com)
  • When an electrical signal is applied to an ultrasonic transducer, it vibrates in a characteristic frequency range and produces sound waves. (hyzerme.com)
  • An ultrasonic transducer is an acoustic sensor. (hyzerme.com)
  • In Linear ultrasonic transducers, the piezoelectric crystals are arranged in a straight line, the beam shape is rectangular, and the near-field resolution is good. (hyzerme.com)
  • They also plan to utilize their novel ultrasound transducer technology for enhanced 3D imaging, which may one day be performed as an advanced point-of-care test. (medgadget.com)
  • This ultrasound transducer is suitable with the GE Logiq ultrasound systems. (strataimaging.com)
  • DualMag transducers combine cold cathode inverted magnetron and MicroPirani thermal conductivity MEMS sensor technologies. (mks.com)
  • This article will consider a variety of excitation methods that can be used in active sensor/transducer applications and will show some typical circuits. (analog.com)
  • Our Seismoprobe Velocity Transducer Systems measure bearing housing, casing and structural vibration. (bakerhughes.com)
  • Since first pioneering recreational fish-finding technology 60 years ago, Lowrance® has changed the landscape of the marine electronics industry with continued sonar and transducer innovation. (lowrance.com)
  • Here are the CHIRP transducers for use with the following compatible product lines: STRIKER™ fishfinder series, echoMAP™ CHIRP and GPSMAP® chartplotter/sonar combo series and GSD™ 25 digital sonar. (gpscentral.ca)
  • This high wide CHIRP traditional and CHIRP DownVü transducer is perfect for the freshwater fisherman who wants excellent CHIRP traditional sonar and scanning sonar with CHIRP DownVü. (gpscentral.ca)
  • Universal Sonar 2 (built-in transducer), i-Pilot Link with spot lock (interfaces with Humminbird sonar), two remote controls, wired foot pedal. (greatlakesfisherman.com)
  • Expert Transducers, available in stationary and rotary styles, are designed for use with Ingersoll Rand's Expert EXTA Torque Analyzer or other analyzers for bidirectional measurement of precisely applied torque and angle on an actual threaded joint or on a joint simulator. (ingersollrand.com)
  • The 972B-21030 DualMag Cold Cathode Vacuum Transducer offers a measurement range from 1x10 -8 Torr to atmospheric pressure and features a size NW25 ISO-KF flange fitting. (mks.com)
  • It has an RS232 digital communication interface for setup of transducer parameters and to provide real time pressure measurement. (mks.com)
  • American Aerospace Controls (AAC) offers state of the art AC and DC current, voltage, power, and frequency transducers used in a wide variety of measurement and control applications. (thomasnet.com)
  • Therefore, it is necessary to use a differential pressure transducer with 10 kPa measurement range (Fig. 8). (researchgate.net)
  • Withstanding temperatures up to 85°C, the Measurement Specialties KPSI Model 342 submersible hydrostatic level transducer provides a 4-20mA analog output. (foodengineeringmag.com)
  • The measurement principle enables the production of force transducers with very high accuracies and comparably low costs . (hbm.com)
  • Accurate measurement of low-level analog signals with a data-acquisition system generally requires more than simply wiring the output of the transducer to the signal conditioning circuitry and then to the analog to digital converter. (analog.com)
  • To maintain high-resolution and accuracy within the measurement system, the designer must exercise care in selecting the excitation source for the transducer-and in the field-wiring scheme used in conveying the low-level analog signal from the transducer to the A/D converter. (analog.com)
  • Raymarine CPT-S Plastic In-Hull CHIRP Transducer - A80691The CPT-S In-hull transducer provides a sim. (yachtbits.com)
  • Many force transducer properties are defined by the selection of the spring element material and design . (hbm.com)
  • Figure 2: Connection of a force transducer with TKzero and TCS adjustment. (hbm.com)
  • A customer reported an s7-3t model transducer displaying a tip temperature of zero degrees celsius. (fda.gov)
  • We offer a wide range of pressure and force transducers for research applications including blood pressure, telemetry, temperature and respiratory measurements. (adinstruments.com)
  • The Transducer element is temperature compensated over a large temperature range. (harvardapparatus.com)
  • Accuracy is excellent for the industrial transducer, less than ±0.3% full scale over pressure and less than ±1.0% full scale over a wide compensated temperature range. (ametekusg.com)
  • Traditional ultrasound transducers are built from bulk piezoelectric materials, in a process that is inefficient and expensive. (medgadget.com)
  • This transducer, named after the arrangement of piezoelectric crystals, called a phased array, is the most commonly used crystal. (hyzerme.com)
  • Finger Pulse Transducers use a piezo-electric element to convert force applied to the active surface of the transducer into an electrical analog signal. (adinstruments.com)
  • These transducers send electrical signals to the object, and once the signal reaches the object, it returns to the transducer. (hyzerme.com)
  • At the end of the transducer, this echo is converted into an electrical signal. (hyzerme.com)
  • Then the transducer calculates the time interval between sending the sound wave and receiving the echo signal. (hyzerme.com)
  • The Accelerometer Stroke Transducer is an accelerometer based transducer generating a real time feedback output signal proportional to machine amplitude to its control system. (syntechtron.com)
  • it is used advantageously in transducer signal-conditioning circuits to remove offset errors, average out 1/f noise and eliminate effects due to parasitic thermocouples. (analog.com)
  • Expression of T-helper 17 cells and signal transducers in patients with psoriasis vulgaris of blood-heat syndrome and blood-stasis syndrome. (bvsalud.org)
  • To investigate the levels of cytokines related to T-helper (Th) 17 cells in serum and signal transducers in the psoriatic lesions of patients with psoriasis vulgaris of blood - heat syndrome (BHS) and blood -stasis syndrome (BSS). (bvsalud.org)
  • Expression levels of signal transducer and activator of transcription 3 (STAT3), p38- mitogen-activated protein kinase (MAPK) and STAT6 in the psoriatic lesions were determined using immunohistochemistry (IHC), Western blot , and real- time quantitative reverse transcription polymerase chain reaction , respectively. (bvsalud.org)
  • Cytokines in serum and signal transducers in the psoriatic lesions alter with various CM syndromes of psoriasis . (bvsalud.org)
  • Patient 2 was an 8-year-old boy with hyperimmunoglobulin-E (Job) syndrome due to mutation in signal transducer and activator of transcription-3 in whom a right-sided pulmonary abscess developed and failed to improve after 1 month of antibacterial therapy. (cdc.gov)
  • An initial signal (pulse) is generated in the computer, sent through the transducer on the patient's neck, and then bounced off a variety of tissue boundaries. (medscape.com)
  • The transducer detects a returning signal (echo). (medscape.com)
  • Distribution of signal transducer and activator of transcription 6 gene G2964A polymorphism in Chinese patients with ulcerative colitis. (cdc.gov)
  • Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease. (cdc.gov)
  • Siemens Healthineers Ultrasound offers a wide range of innovative transducers extending the diagnostic capabilities of your ultrasound system. (siemens-healthineers.com)
  • Moving-coil transducers are less sensitive to impact excitation than integrating accelerometers and can be appropriate for certain applications. (bakerhughes.com)
  • Low-cost, strain force gauge based force transducers, suitable for measuring muscle contractions or similar forces such as in isolated tissue-organ bath experiments in teaching applications. (adinstruments.com)
  • Never use transducers with cracked or damaged housings, acoustic lens, strain relief or cable assemblies as these issues may increase cross-contamination risks and compromise electrical safety features of the transducer. (siemens-healthineers.com)
  • This Transducer can be connected to a standard strain gauge amplifier like a PLUGSYS Module type TAM-A . (harvardapparatus.com)
  • Force transducers based on strain gauges have a so-called spring element or loaded member where the forces to be measured are applied . (hbm.com)
  • Force transducers can be optimized to produce extremely good linearity through the clever selection of the spring element design and through precise positioning of the strain gauges. (hbm.com)
  • These two-wire transducers use moving-coil technology to provide a voltage output that is directly proportional to the transducer's vibration velocity. (bakerhughes.com)
  • It can also emulate analog voltage outputs from a variety of other vacuum transducers. (mks.com)
  • Farmingdale, NY, January 2006 -- American Aerospace Controls (AAC), a leading manufacturer of AC and DC current, voltage, power, and frequency transducers, now offers an AC current transducer that provides superior accuracy over an extended frequency range from 20 Hz to 2 KHz. (thomasnet.com)
  • Active transducers can be excited using a controlled current or voltage. (analog.com)
  • The transducers have been designed and tested to be able to withstand high-level disinfection as recommended by the manufacturers of the Siemens Healthineers approved disinfectant products. (siemens-healthineers.com)
  • Get a real-world, three-dimensional view of fish, structure and bottom contour that makes it easier to know where fish and structure are located in relation to your boat with the StructureScan® 3D transducer with SideScan and DownScan. (lowrance.com)
  • LSS-2 thru-hull StructureScan HD transducers deliver extreme target detail, bottom discrimination, and bait and game fish separation at depths down to 300'/92M and a wider range of 600'/183M with side-to-side coverage. (overtons.com)
  • All StructureScan HD transducers are packed with an enhanced dual-frequency element array that operates at 455 kHz and 800 kHz. (overtons.com)
  • These stainless steel transducers are available only from Navico exclusively for StructureScan HD and StructureScan systems. (overtons.com)
  • This mid-band CHIRP traditional transducer is ideal for the fisherman who wants to install the transducer inside the hull, not on the transom where cavitation could cause issues. (gpscentral.ca)
  • MPX2010 DP differential pressure transducer A) physical model and B). (researchgate.net)
  • These Differential Pressure Transducers are designed for very low differential pressure measurements. (harvardapparatus.com)
  • Setra''s Model 231 is a Multi-configurable, wet-to-wet differential pressure transducer offering the user an all-in-one device with field selectable pressure ranges and analog outputs. (mifasystems.net)
  • El uso de ecografía ha entrado en el campo de la medicina del dolor, anestesia regional y del bibliographic search, data intervencionismo analgésico durante la última década, e incluso es el estándar de la práctica, por tanto, la capacitación y analysis, writing, revision and un adecuado aprendizaje en la ecografía deben ser parte del plan de estudios de cualquier programa de anestesiología. (bvsalud.org)
  • The new 1070 Series AC true RMS current transducers enable accurate and simple comparisons of AC current measurements as well as of dynamic signals, making the transducers ideal for a wide variety of applications. (thomasnet.com)
  • The Disposable Blood Pressure (BP) Transducers are designed to give consistent and accurate readings of arterial and venous blood pressure measurements in animals of all sizes. (adinstruments.com)
  • Demonstrate clinical blood pressure measurements in a lecture, tutorial or practical class with these sphygmomanometers, each of which is coupled to a pressure transducer. (adinstruments.com)
  • Linear regression analysis comparing the Camino and Millar systems yielded a good correlation, and one way analysis of variance showed no difference between the two catheter readings, thus revealing that the recently developed Camino disposable transducer-tipped catheter provides accurate measurements of left ventricular pressure and its first derivative. (who.int)
  • Learn more about the Philips D2tcd PW non-imaging transducer in the specification table below. (philips.com)
  • Learn more about the Philips Lumify L12-4 Linear Array transducer in the specification table below. (philips.no)
  • LEAG: study conception, de datos PubMed y Cochrane, se incluyeron artículos originales, estudios aleatorizados y de revisión, en español y en inglés, manuscript design, publicados entre 2017-2021. (bvsalud.org)
  • The Precision Controls Division (Bellofram PCD) of Marsh Bellofram Corporation, a member of the Marsh Bellofram Group of Companies, has announced its Type 3110 single-loop electro-pneumatic analog circuit-card servo pressure transducer. (designworldonline.com)
  • The Accelerometer Stroke Transducer can be used on machinery operating between 50Hz and 20Hz. (syntechtron.com)
  • This transducer consistently displays clear and crisp fish arches with superior target separation as well as clear definition of structure below the boat. (gpscentral.ca)
  • VOLUME CONTROL GUITAR PICKUP - Adjustable volume level will avoid squeal,The sound clear and crisp,this self-adhesive piezo transducer pickup convenience for Acoustic Classical Guitar Ukulele Violin Cello Mandolin Banjo etc. (noboomusic.com)
  • P58 can be adapted to work with other systems using optional transducer adapter cables, sold separately. (raymarine.com)
  • The low-cost XRS-5 transducer is compatible with a full range of Siemens controllers, from a basic system for high/low alarm or simple pump control, up to advanced control systems with communications, telemetry and SCADA integration capabilities. (siemens.com)
  • Pressure switch transducer combinations monitor pressure levels and switch off systems if the pressure level is exceeded. (grainger.com)
  • These probes used in imaging systems readily incorporate multiple individual transducer assemblies into a single design. (hyzerme.com)
  • At Siemens Healthineers we've incorporated novel thermal management technology along with targeted design optimization of the acoustic stack and transducer body to enable deeper penetration and stronger signals where possible, while meeting regulatory standards. (siemens-healthineers.com)
  • Smart Torque + Angle Transducers include an encoder to measure angle. (ingersollrand.com)
  • In this process, the transducer does not measure the distance of an object by the intensity of the sound. (hyzerme.com)
  • The device uses a modified semiconductor based ultrasound and external tocometry transducers to measure fetal heart rate and maternal contractions respectively. (who.int)
  • The technician moves a transducer (wand-like device) around on your chest. (medlineplus.gov)
  • Photoacoustic imaging capability of the fabricated transducer was also demonstrated by successfully imaging a resolution target and mouse ear vasculatures in vivo, which were irradiated by a 532 nm pulse laser transmitted through the transducer. (nist.gov)
  • We offer complete solutions in all areas of imaging with application-specific transducers and settings. (siemens-healthineers.com)
  • Multi-D - High element density transducers allow dynamic elevation aperture control according to one's imaging needs. (siemens-healthineers.com)
  • The Lumify L12-4 linear array transducer provides high resolution imaging for shallow applications: Soft Tissue, Vascular, Superficial, Musculoskeletal, and Lung. (philips.no)
  • Force transducers can also be used for weighing and for determining torques. (kistler.com)
  • Weighing only 6 oz., the cost-effective transducers are housed in a durable molded plastic case that meets the 94V-O flammability rating. (thomasnet.com)
  • Weighing less than 136 grams, Lumify's battery-free transducers give you lightweight control for ease-of-use and the ultimate advantage in portability. (philips.no)
  • Continuous transducer drift compensator. (cdc.gov)
  • This special element prevents damage to the wear plate or acoustic lens and is supported by a piece of damping material that mutes the transducer after the sound pulse is generated. (hyzerme.com)
  • The internal circuitry of the new transducers are epoxy coated for increased insulation as well as for protection against moisture and foreign contaminants. (thomasnet.com)
  • Current transformers or (CT s), also known as Core Balance Current Transformers or Current Transducers, are instruments that are used to reduce or multiply the current from a high current into a lower current or vice versa. (rs-online.com)
  • Where would I use a Current Transducer? (rs-online.com)
  • AC True RMS Current Transducer feature 0.25% accuracy. (thomasnet.com)
  • ControlAir's Dahl P200 P/I transducer represents outstanding value in pneumatic to current technology. (seeautomation.com)
  • This narrative review describes the main applications of de la ultrasonografía en ultrasound in anesthesia, ultrasound-guided techniques, and current trends in the perioperative anesthetic management of anestesia the surgical patient. (bvsalud.org)
  • The center frequency of the transducer was at 36.9 MHz with 33.9 %, at -6 dB fractional bandwidth. (nist.gov)
  • [ 6 ] The American College of Radiology (ACR) recommends that breast ultrasound be performed with a high-resolution, real-time, linear-array, broad-bandwidth transducer operating at a center frequency of at least 12-MHz and preferably higher. (medscape.com)
  • Transducers, Pressure" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (musc.edu)
  • These methods included a transducer mesh barrier and a staged spray barrier system. (cdc.gov)
  • The sturdy transducer designs are resistant to the electrical forces in the environment where they will be used. (overtons.com)
  • Smart Transducers include a feature that allows them to self-identify themselves to an Expert EXTA Torque Analyzer for easy set-up. (ingersollrand.com)
  • Siemens Echomax transducers are easy to install and require little to no maintenance, handling dust, moisture, vibrations, flooding, and high temperatures without fail. (siemens.com)
  • Our ultra high-frequency transducers, with their unique core acoustic technologies and state-of-the-art design, provide exceptional details of complex areas of interest. (siemens-healthineers.com)
  • The DA Series melt pressure transducers are characterized by their high quality of workmanship and outstanding performance and are used in the plastic manufacturing and processing industries throughout the world. (exportersindia.com)
  • This high wide CHIRP traditional transducer is perfect for the shallow-water fisherman who wants clear definition of the bottom under the boat as well as crisp, clear and wide fish arches with excellent target separation. (gpscentral.ca)
  • This high wide CHIRP traditional transducer is perfect for the ice fisherman who wants clear definition and separation between their bait, fish and the bottom. (gpscentral.ca)
  • With this method, you can get high speed readings without the worry of damaging a transducer mounted on the outside of the boat. (ultimatepassage.com)
  • Ultrasound equipment with a high-resolution linear transducer is necessary. (medscape.com)
  • A range of force transducers are available. (adinstruments.com)
  • The patented technologies of our advanced transducer design accommodate a broad range of examinations and applications, offering unparalleled clinical flexibility and value. (siemens-healthineers.com)
  • Gesture-detecting technology - Advanced accelerometer technology, proprietary software, coupled with gesture-detecting technology enables Siemens Healthineers InTune™ transducers to recognize sonographer interaction. (siemens-healthineers.com)
  • Incorporating automation electronics, such as gesture-detecting technology, into transducers is just one of the many ways Siemens Healthineers is transforming healthcare delivery to improve clinical workflow, allowing clinicians more time to focus on their patients. (siemens-healthineers.com)
  • At Siemens Healthineers one of many transducer design considerations is selecting technology that is best suited for the job. (siemens-healthineers.com)
  • Siemens Healthineers Ultrasound transducers and technology empower you to capture clear, beautiful clinical images. (siemens-healthineers.com)
  • Figure 1 shows a generalized block diagram of a transducer-based data acquisition system. (analog.com)
  • Typical transducer-based data acquisition system. (analog.com)