Transcriptome. Medical search

The pattern of GENE EXPRESSION at the level of genetic transcription in a specific organism or under specific circumstances in specific cells.

The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.

The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.

A multistage process that includes cloning, physical mapping, subcloning, sequencing, and information analysis of an RNA SEQUENCE.

Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.

Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.

A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.

Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium.

The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.

A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.

A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.

The functional hereditary units of PLANTS.

Ribonucleic acid in plants having regulatory and catalytic roles as well as involvement in protein synthesis.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Databases devoted to knowledge about specific genes and gene products.

Overlapping of cloned or sequenced DNA to construct a continuous region of a gene, chromosome or genome.

The simultaneous analysis, on a microchip, of multiple samples or targets arranged in an array format.

A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.

The systematic study of the complete DNA sequences (GENOME) of organisms.

The protein complement of an organism coded for by its genome.

Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.

Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.

The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.

The genetic complement of a plant (PLANTS) as represented in its DNA.

The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.

A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.

Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.

The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different.

Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.

Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)

The relationships of groups of organisms as reflected by their genetic makeup.

Methods used for detecting the amplified DNA products from the polymerase chain reaction as they accumulate instead of at the end of the reaction.

RNA which does not code for protein but has some enzymatic, structural or regulatory function. Although ribosomal RNA (RNA, RIBOSOMAL) and transfer RNA (RNA, TRANSFER) are also untranslated RNAs they are not included in this scope.

A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

The different gene transcripts generated from a single gene by RNA EDITING or ALTERNATIVE SPLICING of RNA PRECURSORS.

The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.

Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.

The reproductive organs of plants.

Sets of enzymatic reactions occurring in organisms and that form biochemicals by making new covalent bonds.

The parts of the messenger RNA sequence that do not code for product, i.e. the 5' UNTRANSLATED REGIONS and 3' UNTRANSLATED REGIONS.

The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.

A plant genus of the family FABACEAE known for the edible beans.

A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).

The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.

The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.

A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)

Characteristic restricted to a particular organ of the body, such as a cell type, metabolic response or expression of a particular protein or antigen.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi.

Any method used for determining the location of and relative distances between genes on a chromosome.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Sequential operating programs and data which instruct the functioning of a digital computer.

In eukaryotes, a genetic unit consisting of a noncontiguous group of genes under the control of a single regulator gene. In bacteria, regulons are global regulatory systems involved in the interplay of pleiotropic regulatory domains and consist of several OPERONS.

Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.

The interactions between a host and a pathogen, usually resulting in disease.

RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.

Mathematical procedure that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components.

Databases containing information about NUCLEIC ACIDS such as BASE SEQUENCE; SNPS; NUCLEIC ACID CONFORMATION; and other properties. Information about the DNA fragments kept in a GENE LIBRARY or GENOMIC LIBRARY is often maintained in DNA databases.

Annual cereal grass of the family POACEAE and its edible starchy grain, rice, which is the staple food of roughly one-half of the world's population.

A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).

Diseases of plants.

The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or other functional RNA.

A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.

Proteins that originate from plants species belonging to the genus ARABIDOPSIS. The most intensely studied species of Arabidopsis, Arabidopsis thaliana, is commonly used in laboratory experiments.

Short RNA, about 200 base pairs in length or shorter, that does not code for protein.

Prolonged dry periods in natural climate cycle. They are slow-onset phenomena caused by rainfall deficit combined with other predisposing factors.

A physiochemical process which occurs in a wide range of organisms which unlike BASAL METABOLISM is not required for or essential to short-term survivability but to long-term general well-being of the organism.

The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.

The genetic complement of a helminth (HELMINTHS) as represented in its DNA.

Proteins found in any species of bacterium.

A plant genus of the family MALVACEAE. It is the source of COTTON FIBER; COTTONSEED OIL, which is used for cooking, and GOSSYPOL. The economically important cotton crop is a major user of agricultural PESTICIDES.

Techniques using a laser to cut away and harvest a specific cell or cluster of cells from a tissue section while viewing it under the microscope.

The systematic study of the complete complement of proteins (PROTEOME) of organisms.

Degree of saltiness, which is largely the OSMOLAR CONCENTRATION of SODIUM CHLORIDE plus any other SALTS present. It is an ecological factor of considerable importance, influencing the types of organisms that live in an ENVIRONMENT.

Proteins found in any species of insect.

The functional hereditary units of INSECTS.

The genetic complement of a BACTERIA as represented in its DNA.

The complete gene complement contained in a set of chromosomes in a fungus.

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

A large order of insects characterized by having the mouth parts adapted to piercing or sucking. It is comprised of four suborders: HETEROPTERA, Auchenorrhyncha, Sternorrhyncha, and Coleorrhyncha.

The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.

The fruiting 'heads' or 'caps' of FUNGI, which as a food item are familiarly known as MUSHROOMS, that contain the FUNGAL SPORES.

A subset of various vascular plants (also known as the Tracheophyta) which include seed-bearing and non seed-bearing species.

Any of the hormones produced naturally in plants and active in controlling growth and other functions. There are three primary classes: auxins, cytokinins, and gibberellins.

A plant genus of the family SALICACEAE. Balm of Gilead is a common name used for P. candicans, or P. gileadensis, or P. jackii, and sometimes also used for ABIES BALSAMEA or for COMMIPHORA.

The first nucleotide of a transcribed DNA sequence where RNA polymerase (DNA-DIRECTED RNA POLYMERASE) begins synthesizing the RNA transcript.

A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event.

Very young plant after GERMINATION of SEEDS.

Commonly observed BASE SEQUENCE or nucleotide structural components which can be represented by a CONSENSUS SEQUENCE or a SEQUENCE LOGO.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.

Ribonucleic acid in helminths having regulatory and catalytic roles as well as involvement in protein synthesis.

The relationship between two different species of organisms that are interdependent; each gains benefits from the other or a relationship between different species where both of the organisms in question benefit from the presence of the other.

A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Proteins obtained from species of fish (FISHES).

A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE).

Deoxyribonucleic acid that makes up the genetic material of plants.

Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.

Nucleotide sequences located at the ends of EXONS and recognized in pre-messenger RNA by SPLICEOSOMES. They are joined during the RNA SPLICING reaction, forming the junctions between exons.

The continuous sequence of changes undergone by living organisms during the post-embryonic developmental process, such as metamorphosis in insects and amphibians. This includes the developmental stages of apicomplexans such as the malarial parasite, PLASMODIUM FALCIPARUM.

A plant genus of the family FABACEAE that is used for food in NIGERIA.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.

The joining of RNA from two different genes. One type of trans-splicing is the "spliced leader" type (primarily found in protozoans such as trypanosomes and in lower invertebrates such as nematodes) which results in the addition of a capped, noncoding, spliced leader sequence to the 5' end of mRNAs. Another type of trans-splicing is the "discontinuous group II introns" type (found in plant/algal chloroplasts and plant mitochondria) which results in the joining of two independently transcribed coding sequences. Both are mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells are also capable of trans-splicing.

Plants that can grow well in soils that have a high SALINITY.

The chromosomal constitution of a cell containing multiples of the normal number of CHROMOSOMES; includes triploidy (symbol: 3N), tetraploidy (symbol: 4N), etc.

The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

Knobbed structures formed from and attached to plant roots, especially of LEGUMES, which result from symbiotic infection by nitrogen fixing bacteria such as RHIZOBIUM or FRANKIA. Root nodules are structures related to MYCORRHIZAE formed by symbiotic associations with fungi.

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.

The body of a fungus which is made up of HYPHAE.

The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.

A multistage process that includes the determination of a sequence (protein, carbohydrate, etc.), its fragmentation and analysis, and the interpretation of the resulting sequence information.

Genotypic differences observed among individuals in a population.

The functional hereditary units of BACTERIA.

DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.

Biological activities and function of the whole organism in human, animal, microorgansims, and plants, and of the biosphere.

A species of the family Ranidae which occurs primarily in the eastern half of the United States and Canada. Two subspecies exist, commonly referred to as green frog (R. c. melanota) and bronze frog (R. c. clamitans).

Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.

PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.

A cell line derived from cultured tumor cells.

Adaptation to a new environment or to a change in the old.

The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.

A plant species of the family POACEAE. It is a tall grass grown for its EDIBLE GRAIN, corn, used as food and animal FODDER.

A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.

Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.

The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.

Elements of limited time intervals, contributing to particular results or situations.

A plant species of the family SOLANACEAE, native of South America, widely cultivated for their edible, fleshy, usually red fruit.

The performance of dissections with the aid of a microscope.

A mitosporic fungal genus. P. brasiliensis (previously Blastomyces brasiliensis) is the etiologic agent of PARACOCCIDIOIDOMYCOSIS.

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

A plant genus of the family POACEAE widely cultivated in the tropics for the sweet cane that is processed into sugar.

Paired sense organs connected to the anterior segments of ARTHROPODS that help them navigate through the environment.

A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.

Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.

A plant genus in the family PINACEAE, order Pinales, class Pinopsida, division Coniferophyta. They are evergreen trees mainly in temperate climates.

A plant genus of the family Plantaginaceae. Members contain scrosides (CINNAMATES) and phenylethanoid glycoside. P. kurrooa is the source of picroliv (a purified iridoid glycoside fraction from the roots having hepatoprotective, anti-inflammatory and antioxidant properties).

Specific regions that are mapped within a GENOME. Genetic loci are usually identified with a shorthand notation that indicates the chromosome number and the position of a specific band along the P or Q arm of the chromosome where they are found. For example the locus 6p21 is found within band 21 of the P-arm of CHROMOSOME 6. Many well known genetic loci are also known by common names that are associated with a genetic function or HEREDITARY DISEASE.

A plant genus of the family ELAEAGNACEAE. Linoleic (18:2n-6) and alpha-linolenic acids (18:3n-3) comprised about 70% of seed oil fatty acids. This is unrelated to 'artificial sea buckthorn oil'. This genus does not belong to the buckthorn family (RHAMNACEAE).

The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

Ligand-binding assays that measure protein-protein, protein-small molecule, or protein-nucleic acid interactions using a very large set of capturing molecules, i.e., those attached separately on a solid support, to measure the presence or interaction of target molecules in the sample.

A plant species of the genus CITRUS, family RUTACEAE that provides the familiar orange fruit which is also a source of orange oil.

A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.

Ribonucleic acid in fungi having regulatory and catalytic roles as well as involvement in protein synthesis.

An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.

A plant genus of the family TAXODIACEAE. Members contain DITERPENES.

A plant genus of the family DENNSTAEDTIACEAE. Members contain ptaquiloside, braxin A1, and braxin B. The name is similar to brake fern (PTERIS).

A plant genus in the family VITACEAE, order Rhamnales, subclass Rosidae. It is a woody vine cultivated worldwide. It is best known for grapes, the edible fruit and used to make WINE and raisins.

The genetic complement of an insect (INSECTS) as represented in its DNA.

New immature growth of a plant including stem, leaves, tips of branches, and SEEDLINGS.

Eighteen-carbon cyclopentyl polyunsaturated fatty acids derived from ALPHA-LINOLENIC ACID via an oxidative pathway analogous to the EICOSANOIDS in animals. Biosynthesis is inhibited by SALICYLATES. A key member, jasmonic acid of PLANTS, plays a similar role to ARACHIDONIC ACID in animals.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Morphological and physiological development of EMBRYOS.

A plant division of GYMNOSPERMS consisting of cone-bearing trees and shrubs.

A method for comparing two sets of chromosomal DNA by analyzing differences in the copy number and location of specific sequences. It is used to look for large sequence changes such as deletions, duplications, amplifications, or translocations.

Parts of plants that usually grow vertically upwards towards the light and support the leaves, buds, and reproductive structures. (From Concise Dictionary of Biology, 1990)

A large family of mollusks in the class BIVALVIA, known commonly as scallops. They possess flat, almost circular shells and are found in all seas from shallow water to great depths.

A plant species of the family FABACEAE used to study GENETICS because it is DIPLOID, self fertile, has a small genome, and short generation time.

An absence of warmth or heat or a temperature notably below an accustomed norm.

Genes that are located on the MITOCHONDRIAL DNA. Mitochondrial inheritance is often referred to as maternal inheritance but should be differentiated from maternal inheritance that is transmitted chromosomally.

A plant genus of the family BRASSICACEAE known for its peppery red root.

A plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. Commercial natural RUBBER is mainly obtained from Hevea brasiliensis but also from some other plants.

Any of the DNA in between gene-coding DNA, including untranslated regions, 5' and 3' flanking regions, INTRONS, non-functional pseudogenes, and non-functional repetitive sequences. This DNA may or may not encode regulatory functions.

Genetic loci associated with a QUANTITATIVE TRAIT.

A plant genus in the family PINACEAE, order Pinales, class Pinopsida, division Coniferophyta. They are coniferous evergreen trees with long, flat, spirally arranged needles that grow directly from the branch.

A genus of basidiomyceteous fungi in the family POLYPORACEAE. The species all contain bright orange, bracket-like fruiting bodies.

The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.

Derivatives of ethylene, a simple organic gas of biological origin with many industrial and biological use.

A plant genus of the family POACEAE. Young shoots are eaten in Asian foods while the stiff mature stems are used for construction of many things. The common name of bamboo is also used for other genera of Poaceae including Phyllostachys, SASA, and Dendrocalamus.

Flagellate EUKARYOTES, found mainly in the oceans. They are characterized by the presence of transverse and longitudinal flagella which propel the organisms in a rotating manner through the water. Dinoflagellida were formerly members of the class Phytomastigophorea under the old five kingdom paradigm.

Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.

The fertilizing element of plants that contains the male GAMETOPHYTES.

A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.

Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.

The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.

A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.

The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide using energy obtained from light rather than from the oxidation of chemical compounds. Photosynthesis comprises two separate processes: the light reactions and the dark reactions. In higher plants; GREEN ALGAE; and CYANOBACTERIA; NADPH and ATP formed by the light reactions drive the dark reactions which result in the fixation of carbon dioxide. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)

Plant tissue that carries water up the root and stem. Xylem cell walls derive most of their strength from LIGNIN. The vessels are similar to PHLOEM sieve tubes but lack companion cells and do not have perforated sides and pores.

A group of alicyclic hydrocarbons with the general formula R-C5H9.

The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)

The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.

Proteins synthesized by organisms belonging to the phylum ARTHROPODA. Included in this heading are proteins from the subdivisions ARACHNIDA; CRUSTACEA; and HORSESHOE CRABS. Note that a separate heading for INSECT PROTEINS is listed under this heading.

Paired respiratory organs of fishes and some amphibians that are analogous to lungs. They are richly supplied with blood vessels by which oxygen and carbon dioxide are exchanged directly with the environment.

Inorganic compounds that include a positively charged tetrahedral nitrogen (ammonium ion) as part of their structure. This class of compounds includes a broad variety of simple ammonium salts and derivatives.

Effects of basic fibroblast growth factor on the expressions of angiogenic gene profile and cyclooxygenase-2 in brain microvascular endothelial cells. (1/4463)

The present study aimed to investigate the effects of basic fibroblast growth factor (bFGF) on the expressions of angioge-nesis-related genes in a mouse brain microvascular endothelial cell line, namely bEnd.3, using cDNA microarray. The effects of bFGF (10 ng/ml) on mRNA and protein expressions of cyclooxygenase-2 (COX-2), an angiogenesis bystander molecule, were further investigated. cDNA microarray was employed to study the effects of bFGF on the expressions of angiogenic genes in a high throughput pattern. RT-PCR was used to study the effect of bFGF on COX-2 mRNA expression. Western blot and immunocytochemistry were utilized to study the effect of bFGF on COX-2 protein expression. The results showed that, 2 h after bFGF treatment, pro-angiogenic genes (Adamts1, MMP-9, Ang-1, PDGF B, G-CSF, FGF16, IGF-1, etc.) were significantly upregulated, whereas anti-angiogenic genes (TIMP-2, TSP-3, etc.) were significantly downregulated. The bystander molecule in angiogenic pathway COX-2 mRNA and protein expressions were significantly upregulated after bFGF treatment. It is suggested that triggering angiogensis switch through upregulating pro-angiogenic gene and downregulating anti-angiogenic gene expression is one of the major mechanisms of bFGF-induced angiogenesis. The expression change of COX-2, as a bystander molecule, was observed after bFGF treatment in bEnd.3 cells and the significance was discussed. (+info)

Stress-dependent coordination of transcriptome and translatome in yeast. (2/4463)

(+info)

Variation in dehydration tolerance, ABA sensitivity and related gene expression patterns in D-genome progenitor and synthetic hexaploid wheat lines. (3/4463)

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Identification and classification of small RNAs in transcriptome sequence data. (4/4463)

Current methods for high throughput sequencing (HTS) for the first time offer the opportunity to investigate the entire transcriptome in an essentially unbiased way. In many species, small non-coding RNAs with specific secondary structures constitute a significant part of the transcriptome. Some of these RNA classes, in particular microRNAs and snoRNAs, undergo maturation processes that lead to the production of shorter RNAs. After mapping the sequences to the reference genome specific patterns of short reads can be observed. These read patterns seem to reflect the processing and thus are specific for the RNA transcripts of which they are derived from. We explore here the potential of short read sequence data in the classification and identification of non-coding RNAs. (+info)

The transcriptome of human monocyte subsets begins to emerge. (5/4463)

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A focus on natural variation for abiotic constraints response in the model species Arabidopsis thaliana. (6/4463)

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A marginal mixture model for selecting differentially expressed genes across two types of tissue samples. (7/4463)

(+info)

Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNalpha antibody, in systemic lupus erythematosus. (8/4463)

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There are several -ome fields that can be seen as subcategories of the transcriptome. The exome differs from the transcriptome ... One Thousand Plant Transcriptomes Initiative (23 October 2019). "One thousand plant transcriptomes and the phylogenomics of ... There are numerous publicly available transcriptome databases. The word transcriptome is a portmanteau of the words transcript ... The transcriptome can be seen as a subset of the proteome, that is, the entire set of proteins expressed by a genome. However, ...

https://en.wikipedia.org/wiki/Transcriptome

... a phenomenon referred to as transcriptome instability. Transcriptome instability correlates significantly with reduced ... Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers. In general, pre-mRNA ... Sveen, A; Ågesen, TH; Nesbakken, A; Rognum, TO; Lothe, RA; Skotheim, RI (2011). "Transcriptome instability in colorectal cancer ... Sveen, A; Johannessen, B; Teixeira, MR; Lothe, RA; Skotheim, RI (2014). "Transcriptome instability as a molecular pan-cancer ...

https://en.wikipedia.org/wiki/Transcriptome_instability

... (DTS) is a bioinformatics method to detect the presence of novel pathogen transcripts through ... Feng H, Taylor JL, Benos PV, Newton R, Waddell K, Lucas SB, Chang Y, Moore PS (August 2007). "Human Transcriptome Subtraction ... Must have a highly reliable, complete reference transcriptome for the organism being studied. Lack of foreign sequence ... "New Pathogen Discovery: Digital Transcriptome Subtraction". Archived from the original on 25 January 2010. Retrieved 1 March ...

https://en.wikipedia.org/wiki/Digital_transcriptome_subtraction

... is the de novo sequence assembly method of creating a transcriptome without the aid of a ... 2011). "Reptilian transcriptome v1.0, a glimpse in the brain transcriptome of five divergent Sauropsida lineages and the ... Transcriptome Transcriptomics Human-transcriptome database for alternative splicing (H-DBAS) UniGene Full-parasites Exome ... SeqMan NGen, part of DNASTAR's software pipeline, includes a de novo transcriptome assembler for small or large transcriptome ...

https://en.wikipedia.org/wiki/De_novo_transcriptome_assembly

... (TWAS) is a statistical genetics methodology to improve detection power and provide ... September 2015). "A gene-based association method for mapping traits using reference transcriptome data". Nature Genetics. 47 ( ... March 2016). "Integrative approaches for large-scale transcriptome-wide association studies". Nature Genetics. 48 (3): 245-252 ...

https://en.wikipedia.org/wiki/Transcriptome-wide_association_study

The transcriptome is a set of all RNA, including rRNA, mRNA, tRNA, and non-coding RNA. Specifically mRNA transcripts can be ... A transcriptome in vivo analysis tag (TIVA tag) is a multifunctional, photoactivatable mRNA-capture molecule designed for ... February 2014). "Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue". Nat. Methods. 11 (2 ... Transcriptome profiling is determining the composition of transcripts and their relative expression levels in a given reference ...

https://en.wikipedia.org/wiki/Transcriptome_in_vivo_analysis_tag

The Human-transcriptome DataBase for Alternative Splicing (H-DBAS) is a database of alternatively spliced human transcripts ...

https://en.wikipedia.org/wiki/Human-transcriptome_DataBase_for_Alternative_Splicing

Transcriptome analysis. Epigenome analysis. Oral Microbiome analysis. 2013 Recruitment of TMM Community-Based Cohort starts. ... As of 2022, jMorp covers metabolome, proteome, transcriptome, methylome, as well as genome reference panel. 2016 Recruitment of ... "Intraindividual dynamics of transcriptome and genome-wide stability of DNA methylation". Scientific Reports. 6: 26424. Bibcode: ...

https://en.wikipedia.org/wiki/Tohoku_Medical_Megabank_Project

Other than transcriptome shotgun sequencing, this technique has been called RNA-seq and whole transcriptome shotgun sequencing ... One Thousand Plant Transcriptomes Initiative (October 2019). "One thousand plant transcriptomes and the phylogenomics of green ... Since only the transcriptome was sequenced, the project did not reveal information about gene regulatory sequence, non-coding ... The 1000 Plant Transcriptomes Initiative (1KP) was an international research effort to establish the most detailed catalogue of ...

https://en.wikipedia.org/wiki/1000_Plant_Genomes_Project

The control Transcriptomes users are able to use them as an avatar, such as Camael. Usually, Quanxs are born naturally, but ... They're Transcriptome. He appeared as a character of Denma with NAVER WEBTOON. He appeared as a hero in Densinma with NAVER ... The object Quanx Transcriptome is one of the most fiercely competed secret project done by the universe eight munitions ... She's Yahwah's Transcriptome. Arcel (Korean: 아셀; RR: Asel): He's first appeared in Chapter 1 Ep. 4 - Eve Rachel (2) - #14. He ...

https://en.wikipedia.org/wiki/Denma

"Illumina bodyMap2 transcriptome". NCBI (National Center for Biotechnology Information) BioProject. Szabo L, Morey R, Palpant NJ ... April 2004). "A gene atlas of the mouse and human protein-encoding transcriptomes". Proceedings of the National Academy of ...

https://en.wikipedia.org/wiki/SLC46A3

Hrdlickova R, Toloue M, Tian B (2017 January). "RNA-Seq methods for transcriptome analysis". Wiley Online Library. 8(1). ... Cieślik M, Chinnaiyan AM (2018 February). "Cancer transcriptome profiling at the juncture of clinical translation". Nature ... Martin JA, Wang Z (2011 September). "Next-generation transcriptome assembly". Nature Reviews Genetics. 12(10):671-82. 10.1038/ ... "Single-cell sequencing of the small-RNA transcriptome". Nature Biotechnology. 34(12):1264-1266. 10.1038/nbt.3701. PMID 27798564 ...

https://en.wikipedia.org/wiki/Small_RNA_sequencing

Deciphering the Cancer Transcriptome. 2016 Vega F, Medeiros LJ (September 2003). "Chromosomal translocations involved in non- ... March 2009). "Transcriptome sequencing to detect gene fusions in cancer". Nature. 458 (7234): 97-101. Bibcode:2009Natur.458... ... However, the precondition for large scale detection is a paired-end sequencing of the cell's transcriptome. The direction of ... Some researchers already developed a new tool called Transcriptome Viewer (TViewer) to directly visualize detected gene fusions ...

https://en.wikipedia.org/wiki/Fusion_gene

Richard A. Stein (2020-06-23). "Deciphering the Cancer Transcriptome". Retrieved 2022-06-23. Root Gorelick (2010-11-20). "Sex ...

https://en.wikipedia.org/wiki/Henry_Heng

Goh SH, Josleyn M, Lee YT, Danner RL, Gherman RB, Cam MC, Miller JL (July 2007). "The human reticulocyte transcriptome". ...

https://en.wikipedia.org/wiki/C16orf82

Extension Poly(A) Test GeneCalling, an mRNA profiling technology Missense mRNA mRNA display mRNA surveillance Transcriptome, ... "The human mitochondrial transcriptome". Cell. 146 (4): 645-658. doi:10.1016/j.cell.2011.06.051. PMC 3160626. PMID 21854988. ...

https://en.wikipedia.org/wiki/Messenger_RNA

Multicellgenome, Lab; Guifré, Torruella (2017-09-26). "Transcriptome - Parvularia atlantis (Nuclearia sp. ATCC 50694)". ...

https://en.wikipedia.org/wiki/Parvularia_atlantis

A transcriptome sequence is determined. Paramecium bursaria with green zoochlorellae living inside endosymbiotically A ...

https://en.wikipedia.org/wiki/Paramecium_bursaria

Single-cell transcriptomes are now well described and have even been extended to in situ RNA-Seq where transcriptomes of ... Transcriptome databases getting bigger and more useful as transcriptomes continue to be collected and shared by researchers. It ... Aging has been shown to be a strong driver of transcriptome changes. Aging clocks based on transcriptomes have suffered from ... RNA-Seq leverages deep sampling of the transcriptome with many short fragments from a transcriptome to allow computational ...

https://en.wikipedia.org/wiki/Transcriptomics_technologies

Spellman and Rubin (2002) made a transcriptome map of Drosophila. Of all assayed genes 20% was clustered. Clusters consisted of ... Yamashita T, Honda M, Takatori H, Nishino R, Hoshino N, Kaneko S (November 2004). "Genome-wide transcriptome mapping analysis ... 2001) made a human transcriptome map of 12 different tissues (cancer cells) and concluded that genes are not randomly ... September 2003). "The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern ...

https://en.wikipedia.org/wiki/Ridge_(biology)

Kocabas, A. M., Crosby, J., Ross, P. J., Otu, H. H., Beyhan, Z., Can, H., ... & Fernandez, E. (2006). The transcriptome of ...

https://en.wikipedia.org/wiki/Tex36

These studies led Velculescu to coin the term transcriptome in a 1997 paper to describe the comprehensive gene expression ... "Characterization of the yeast transcriptome". Cell. 88 (2): 243-51. doi:10.1016/s0092-8674(00)81845-0. PMID 9008165. S2CID ...

https://en.wikipedia.org/wiki/Victor_Velculescu

Mutations in the insect transcriptome. J Clin Exp Pathol. 2016; 6: 3. 13. Picimbon JF. A new view of genetic mutations. ... Transcriptome exploration of the sex pheromone gland of Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae). Parasit ... Zhu J, Wang G, Pelosi P. Plant transcriptomes reveal hidden guests. Biochem Biophys Res Commun. 2016; 474: 497-502. 27. Perkin ...

https://en.wikipedia.org/wiki/Chemosensory_protein

Antennal transcriptome of Manduca sexta. Proceedings of the National Academy of Sciences of the United States of America, 108, ...

https://en.wikipedia.org/wiki/Bill_S._Hansson

Human Genome Project In silico Transcriptome Genesis Partners List of Israeli companies quoted on the Nasdaq Compugen 2016 ... Xie, Hanqing; Gill-More, Raveh (2004). "Transcriptome Analysis Through Expressed Sequences". In Seckbach, Joseph; Rubin, Eitan ...

https://en.wikipedia.org/wiki/Compugen_(Israeli_company)

"The transcriptome of human oocytes". Proceedings of the National Academy of Sciences of the United States of America. 103 (38 ... "The transcriptome of human oocytes". Proceedings of the National Academy of Sciences of the United States of America. 103 (38 ...

https://en.wikipedia.org/wiki/FAM76A

Casella G, Munk R, Kim KM, Piao Y, De S, Abdelmohsen K, Gorospe M (August 2019). "Transcriptome signature of cellular ...

https://en.wikipedia.org/wiki/Cellular_senescence

"Transcriptome analysis of human gastric cancer". Mammalian Genome. 16 (12): 942-54. doi:10.1007/s00335-005-0075-2. PMID ...

https://en.wikipedia.org/wiki/CENTG2

"Transcriptome analysis of human gastric cancer". Mammalian Genome. 16 (12): 942-54. doi:10.1007/s00335-005-0075-2. PMID ...

https://en.wikipedia.org/wiki/CITED2

"Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942-54. doi:10.1007/s00335-005-0075-2. PMID 16341674. ...

https://en.wikipedia.org/wiki/TGS1

... Glia. 2018 Dec;66(12):2604-2616. doi: 10.1002/glia.23514. Epub 2018 ... In this study, we sought to quantify the astrocytic AMPAR transcriptome during brain development and with respect to selected ...

https://pubmed.ncbi.nlm.nih.gov/30370555/

The metabolome and transcriptome of the maize-infecting fungi Ustilago maydis and Fusarium verticillioides were analyzed as the ... Metabolome and transcriptome of the interaction between Ustilago maydis and Fusarium verticillioides in vitro. 1st May 2012 ... The metabolome and transcriptome of the maize-infecting fungi Ustilago maydis and Fusarium verticillioides were analyzed as the ... Metabolome and transcriptome of the interaction between Ustilago maydis and Fusarium verticillioides in vitro. ...

https://www.jic.ac.uk/research-impact/publications/metabolome-and-transcriptome-of-the-interaction-between-ustilago-maydis-and-fusarium-verticillioides-in-vitro/

Large-scale assessment of transcriptome analysis software. Bertone et al. Nat Methods 2013 Tags: ENCODE, Gene expression, RNA- ...

https://www.ebi.ac.uk/about/news/technology-and-innovation/RGASP-2013/

By characterizing the transcriptome patterns and pathways for these symptoms, our goal is to shed light on the biological ... Longitudinal Genome-wide Transcriptome Study of PTSD Symptom Change in WTC Responders. ...

https://wwwn.cdc.gov/ResearchGateway/ResearchProjects/Details/138

Comments on GSE57109: A new dataset of spermatogenic vs oogenic transcriptomes in the nematod C. elegans ... GSE57109: A new dataset of spermatogenic vs oogenic transcriptomes in the nematod C. elegans ... GSE57109: A new dataset of spermatogenic vs oogenic transcriptomes in the nematod C. elegans ...

https://wormbase.org/resources/analysis/RNASeq.elegans.WBStrain00000001.WBls:0000002.Hermaphrodite.WBbt:0006797.SRP041461.SRX527961

The individual cell transcriptomes also pointed to the presence of previously unappreciated cell type markers and expression- ... Normal Breast Cell Types, States Characterized by Single-Cell Transcriptome Analysis Apr 29, 2020 , Andrea Anderson ... With the single-cell transcriptomes, the team saw expression clusters corresponding to around a dozen major and minor non- ...

https://www.genomeweb.com/sequencing/normal-breast-cell-types-states-characterized-single-cell-transcriptome-analysis

RiboMinus Transcriptome Isolation Kits are novel purification systems that enrich the whole spectrum of RNA transcripts by ...

https://www.thermofisher.com/order/catalog/product/K155004

A game-changing new chapter in the history of evolution has been opened after two-million-year-old DNA has been identified for the first time. Researchers discovered microscopic…. Read More ...

https://scitechdaily.com/tag/transcriptome/

The feature of distinct transcriptomes between ECRSwNP and non-ECRSwNP suggests the necessity to develop specific biomarkers ... We showed eosinophilic CRSwNP (ECRSwNP) and noneosinophilic CRSwNP (non-ECRSwNP) display distinct transcriptome profiles. We ... we performed next-generation RNA sequencing and a comprehensive bioinformatics analyses to characterize the transcriptome ... Transcriptome profile of RNA-Seq data distinguishing three groups.. (A) A volcano plot of differentially expressed transcripts ...

https://www.nature.com/articles/srep26604?error=cookies_not_supported&code=fd519be9-ce1c-43c4-a405-5ce9e94cb60e

Transcriptome and genome sequencing uncovers functional variation in humans ... Transcriptome and genome sequencing uncovers functional variation in humans Lappalainen, Tuuli (författare) Sammeth, Michael ( ... Altogether, this study provides a deep understanding of the cellular mechanisms of transcriptome variation and of the landscape ...

https://swepub.kb.se/showrecord?q=onr%3A%22swepub%3Aoai%3ADiVA.org%3Auu-207901%22&n=1&d=swepub&noredirect=true

We used Illumina® Next Generation Sequencing (NGS) technology to gain unbiased biological insight into the transcriptome of ... This study reveals previously unknown consequences of nicotine stress on the transcriptome of normal breast epithelial cells ...

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067252

... ...

https://www.ei-resource.org/research/autism-research/immune-transcriptome-alterations-in-the-temporal-cortex-of-subjects-with-autism/

... yet the transcriptome-wide elucidation of the Doxlipo formulations remains elusive. To this end, we explored the impact of two ... Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery Ying Li,1,2 Meng Wang,1,2 Bu-Wei Huang,1, ... yet the transcriptome-wide elucidation of the Doxlipo formulations remains elusive. To this end, we explored the impact of two ...

https://www.dovepress.com/transcriptome-wide-elucidation-of-liposomal-formulations-for-anticance-peer-reviewed-fulltext-article-IJN

Home / Beyond the Genome: Transcriptome Based Diagnostics for Rare Diseases and Cancer ...

https://genomecanada.ca/project/beyond-genome-transcriptome-based-diagnostics-rare-diseases-and-cancer/

This study represents the most comprehensive analysis of the drought-response transcriptome of chickpea available to date. It ... A solution to the current stagnation is expected from innovative molecular tools such as transcriptome analyses providing ... 24/11/2008). SuperSAGE: the drought stress-responsive transcriptome of chickpea roots. BMC Genomics. ...

https://www.icarda.org/publications/22044/supersage-drought-stress-responsive-transcriptome-chickpea-roots

... by RIKEN ... They also sequenced the transcriptome of the most devastating Striga species.. The team identified roughly 35,000 protein- ... Citation: The genome and transcriptome of the parasitic plant Striga sequenced (2019, December 6) retrieved 9 December 2022 ... from https://phys.org/news/2019-12-genome-transcriptome-parasitic-striga-sequenced.html ...

https://phys.org/news/2019-12-genome-transcriptome-parasitic-striga-sequenced.html

AGOUTI: improving genome assembly and annotation using transcriptome data. Simo V. Zhang, Luting Zhuo, Matthew W. Hahn ... AGOUTI: improving genome assembly and annotation using transcriptome data Message Subject (Your Name) has forwarded a page to ... We present AGOUTI (Annotated Genome Optimization Using Transcriptome Information), a tool that uses RNA-seq data to ...

https://www.biorxiv.org/content/10.1101/033019v1

... Gandal MJ, Zhang P, Hadjimichael E ... Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Wang, PhD, D. Transcriptome-Wide ... Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder ... 2018). Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science, 362(6420). pii: ...

https://www.waisman.wisc.edu/publications/transcriptome-wide-isoform-level-dysregulation-in-asd-schizophrenia-and-bipolar-disorder/

Changes in human airway cells transcriptome during epithelial wound repair. Beata Narozna, Wojciech Langwiński, Zuzanna ... Changes in human airway cells transcriptome during epithelial wound repair. Beata Narozna, Wojciech Langwiński, Zuzanna ... Changes in human airway cells transcriptome during epithelial wound repair. Beata Narozna, Wojciech Langwiński, Zuzanna ... Conclusion: Human transcriptome is altered during wound repair in airway epithelium in vitro, revealing the genetic mechanisms ...

https://erj.ersjournals.com/content/58/suppl_65/PA3685

Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea. *. ... StringTie enables improved reconstruction of a transcriptome from RNA-seq reads.. Nat. Biotechnol. 2015; 33: 290-295. View in ... SuperTranscripts: a data driven reference for analysis and visualisation of transcriptomes.. Genome Biol. 2017; 18: 160. View ... Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea ...

https://www.cell.com/immunity/fulltext/S1074-7613

... in our blood transcriptome dataset. Genome-wide analysis of lncRNAs expression in VL has never been performed. lncRNAs h... ... in our blood transcriptome dataset. Genome-wide analysis of lncRNAs expression in VL has never been performed. lncRNAs have ... In this regard, blood transcriptomes of human VL caused by L. donovani have been explored by others in India (9), with a focus ... Blood transcriptomes obtained by mRNA-seq allowed us to surpass the typical analyses comprising gene pathways and protein ...

https://www.frontiersin.org/articles/10.3389/fimmu.2022.784463/full

Regulatory network mapping identified downregulated FOXO1 as master transcription factor resulting in altered transcriptome of ... Interaction analysis highlighted contribution of miRNA to altered transcriptome. Functional annotation revealed metabolic ... we performed transcriptome-wide RNA-seq and small RNA-seq on synovial fibroblasts from rheumatoid arthritis (RA) subject and ... signatures associated with RASF and revealed the involvement of transcription factors and miRNA in an altered transcriptome. ...

https://www.mdpi.com/2075-4418/9/3/98/htm

Evidence of neutral transcriptome evolution in plants. Title. Evidence of neutral transcriptome evolution in plants. ... Printed from /publications/evidence-neutral-transcriptome-evolution-plants on 30/11/22 07:40:04 AM ...

https://www.hutton.ac.uk/publications/evidence-neutral-transcriptome-evolution-plants

Our approach explores transcriptome structure and incorporates a maximum likelihood model into the assembly and quantification ... We present MaLTA, a method for simultaneous transcriptome assembly and quantification from Ion Torrent RNA-Seq data. ... Experimental results suggest increased transcriptome assembly and quantification accuracy of MaLTA-IsoEM solution compared to ... can generate whole transcriptome information at the single transcript level providing a powerful tool with multiple ...

https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-S5-S7/figures/4

We sequence single-cell transcriptomes from >1000 fresh and cryopreserved cells using 3-end and full-length RNA preparation ... Single-cell transcriptome conservation in cryopreserved cells and tissues. Access & Citations. * 23k Article Accesses. ...

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1171-9/metrics

Transcriptome-Supervised Classification of Tissue Morphology Using Deep Learning * Transcriptome-Supervised Classification of ... Transcriptome-Supervised Classification of Tissue Morphology Using Deep Learning 0 views * Share * Embed. Static Responsive ... Here we conjecture that spatially resolved gene expression, e.i., the transcriptome, can be used as an alternative to manual ... Here we conjecture that spatially resolved gene expression, e.i., the transcriptome, can be used as an alternative to manual ...

https://ieeetv.ieee.org/ondemand/ieee-isbi-2020-virtual-conference-april-2020/2763/transcriptomesupervised-classification-of-tissue-morphology-using-deep-learning

Transcriptome profiling of hBMSC-HLCs. To investigate the differences in transcriptome profiling of hBMSCs and hBMSC-HLCs, we ... Shi D, Xin J, Lu Y, Ding W, Jiang J, Zhou Q, Sun S, Guo B, Zhou X, Li J. Transcriptome Profiling Reveals Distinct Phenotype of ... Conclusion: hBMSC-HLCs possess a hepatic transcriptome profile and express hepatic-specific genes in vitro and in vivo, which ... Shi D, Xin J, Lu Y, Ding W, Jiang J, Zhou Q, Sun S, Guo B, Zhou X, Li J. Transcriptome Profiling Reveals Distinct Phenotype of ...

https://medsci.org/v17p0263.htm

... full cDNA shotgun sequencing has become a major approach in the study of transcriptomes, and several different protocols in 454 ...

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-13-247/figures/1

Profiling of the transcriptome. The principal component analysis (PCA) was used to analyze the overall variation of transcripts ... The results of transcriptome analysis showed that the expression of structural genes involved in anthocyanin synthesis was ... The fruits in Stage1-6 with 0 and 1000 mg/ml ABA treatment were further transcriptome analysis. The raw bases of each sample ... Transcriptome Analysis Revealed The Mechanism of Exogenous ABA Increasing Anthocyanins in Blueberry Fruit During Veraison ...

https://www.researchsquare.com/article/rs-88852/v1

Transcriptome-Wide Changes in Chlamydomonas reinhardtii Gene Expression Regulated by Carbon Dioxide and the CO2-Concentrating ...

https://digitalcommons.unl.edu/statisticsfacpub/13/

Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. (yale.edu)
Dietary supplementation with vitamin k affects transcriptome and proteome of Senegalese sole, improving larval performance and quality. (ualg.pt)
Our recent work has employed systems biology approaches in which we intrgrated transcriptome, proteome and ubiquitome information to identify Cullin E3 ubiquitin ligases that are particularly active as T cells transition from resting to activated states. (upenn.edu)

This study reveals previously unknown consequences of nicotine stress on the transcriptome of normal breast epithelial cells and provides insight into the underlying biological influence of nicotine on normal cells, marking the foundation for future studies. (vt.edu)
Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells. (physiciansweekly.com)
2016). The transcriptome reveals specific databases transcripts produced under biotic stress (e.g., smut) and abiotic TGICL TIGR gene indices clustering tools stress (e.g., drought) conditions in sugarcane (Iskandar et al. (deepdyve.com)

Here, we performed next-generation RNA sequencing and a comprehensive bioinformatics analyses to characterize the transcriptome profiles, including mRNAs and long noncoding RNAs (lncRNAs), in patients with eosinophilic and noneosinophilic CRSwNP. (nature.com)
A solution to the current stagnation is expected from innovative molecular tools such as transcriptome analyses providing insight into stress-related gene activity, which combined with molecular markers and expression (e)QTL mapping, may accelerate knowledge-based breeding. (icarda.org)
Huang W , Shi X , Chen Y , Zhang Q , Peng J , Zheng S , Wu K . Comparative pharyngeal cartilage developmental toxicity of bisphenol A, bisphenol S and bisphenol AF to zebrafish (Danio rerio) larvae: A combination of morphometry and global transcriptome analyses. (wjgnet.com)

We analyzed the changes in transcriptome during the wound repair in a cell culture model of human bronchial epithelium. (ersjournals.com)
Neoplastic transformation and changes in transcriptome induced by riebeckite/tremolite asbestiform and nonasbestiform elongate mineral particles in human mesothelial cells. (cdc.gov)

The main aim of our study was to observe whether there are alterations in human transcriptome during the repair of bronchial epithelial cells. (ersjournals.com)
Human transcriptome is altered during wound repair in airway epithelium in vitro, revealing the genetic mechanisms of this process, suggesting pathways potentially relevant in abnormal wound repair. (ersjournals.com)
Grinev Vasily V., Nazarov Petr V., Klimov Eugene A.. Power-law Behavior of the Alternative Splicing of Exons in Human Transcriptome. (who.int)

According to Shomron 7 (2010), this field of the clinical pharmacology studies the contribution of genomes, transcriptomes and proteomes in determining drug-response phenotypes (safety and efficacy). (bvsalud.org)

Beyond the biological processes involved in the immunopathology of VL revealed by the expression of protein coding genes (PCGs), we observed a significant participation of long noncoding RNAs (lncRNAs) in our blood transcriptome dataset. (frontiersin.org)
In this dataset, next-generation sequencing was used to sequence root and leaf transcriptomes of the two potato cultivars at two time points in the growing season. (biomedcentral.com)
Contains the Transcriptome Shotgun Assembly Sequence Dataset of Myrciaria dubia 'camu-camu' during seeds germination and initial growth of seedlings (until the first month). (mendeley.com)
Here, we introduce a new method, Summary-level Unified Method for Modeling Integrated Transcriptome (SUMMIT), to improve the expression prediction model accuracy and the power of TWAS by using a large expression quantitative trait loci (eQTL) summary-level dataset. (bvsalud.org)

This study produced a comprehensive transcriptome from newly molted adult ticks and will provide a useful resource for studies of tick feeding and host perception and also assist genome annotation refinements. (usda.gov)

By characterizing the transcriptome patterns and pathways for these symptoms, our goal is to shed light on the biological mechanisms underlying this comorbidity, which can help prevent the exacerbation of physical symptoms by intervening at the level of etiological pathway. (cdc.gov)
We annotated PETs to pathways of KEGG database and compared the murine B16F1 melanoma transcriptome with three non-melanoma murine transcriptomes (Melan-a2 melanocytes, E14 embryonic stem cells, and E17.5 embryo). (biomedcentral.com)
2018), we Introduction employed transcriptome profiling to analyze the genes and pathways involved in twist leaf disease in modern sugarcane Sugarcane belongs to the Poaceae family, which includes cultivar. (deepdyve.com)

Thermal plasticity of the miRNA transcriptome during Senegalese sole development. (ualg.pt)

In this report, we used RNA-seq, which allows genome-wide gene expression analysis to sequence the transcriptomes of the subclonal Russet Norkotah selection TXNS278 with standard Russet Norkotah grown in commercial fields. (biomedcentral.com)

Lineage abundance estimation for SARS-CoV-2 in wastewater using transcriptome quantification techniques. (harvard.edu)

Overview of nanopore inferred transcriptome. (biomedcentral.com)

Recent studies utilizing transcriptome sequences generated by next generation sequencing (NGS) technologies have demonstrated the ability to rapidly detect and characterize thousands of gene-based microsatellites from different plants. (datadryad.org)
Here we applied the robust Gene Identification Signature Paired End diTag (GIS-PET) approach to investigate the melanoma transcriptome and characterize the global pathway aberrations. (biomedcentral.com)

Transcriptome analysis was used to study alterations in gene expression in the domesticated masked palm civet after chronic infection with T. gondii . (biomedcentral.com)

Conclusions: We demonstrate here that a single transcriptome sequence is sufficient to identify hundreds of polymorphic SSR markers. (soton.ac.uk)
These transcriptomic data of A. davidianus should open the door to molecular evolution studies based on the entire transcriptome or targeted genes of interest to sequence. (rna-seqblog.com)

We present AGOUTI (Annotated Genome Optimization Using Transcriptome Information), a tool that uses RNA-seq data to simultaneously combine contigs into scaffolds and fragmented gene models into single models. (biorxiv.org)
In addition, the utility of transcriptome data for marker development is demonstrated. (soton.ac.uk)
The primer subsets from transcriptome data proved highly useful for detecting polymorphisms in the related species, supporting the finding that NGS is an efficient approach to molecular marker development at both intra- and inter- species levels, especially in endangered non-model species. (datadryad.org)
In conclusion, while the evidence for a major effect of lactation on the endometrial transcriptome is relatively weak, these data suggest that the metabolic status of the animal (heifer vs cow) modulates the response of the endometrium to the developing conceptus. (whiterose.ac.uk)
In summary, our RNA-Seq transcriptome data provide an overview of gene expression in male meiocytes and invaluable information for future functional studies. (elsevier.com)

Here we used RNA sequencing to explore the transcriptome of a single plant cell type, the Arabidopsis male meiocyte, detecting the expression of approximately 20 000 genes. (elsevier.com)

We showed eosinophilic CRSwNP (ECRSwNP) and noneosinophilic CRSwNP (non-ECRSwNP) display distinct transcriptome profiles. (nature.com)
The feature of distinct transcriptomes between ECRSwNP and non-ECRSwNP suggests the necessity to develop specific biomarkers and personalized therapeutic strategies. (nature.com)
The results revealed constitutively differential gene expression before stress and distinct global transcriptome reprogramming among the three genotypes under a time series of drought stress, consistent with their different genotypes and DT phenotypes. (biomedcentral.com)

Although several strategies are available for generating BMSC-HLCs, these cells are still less effective than HHs in repopulating the liver, and the transcriptome mechanism is still unclear [ 2 , 9 - 11 ]. (medsci.org)

With the single-cell transcriptomes, the team saw expression clusters corresponding to around a dozen major and minor non-adipose breast cell types. (genomeweb.com)
The individual cell transcriptomes also pointed to the presence of previously unappreciated cell type markers and expression-based cell states not described in the past, Kumar noted. (genomeweb.com)
Gene expression was identified at several time points: before the injury and 4, 8, 16, 24 hours after injury with SurePrint G3 Human Gene Expression whole transcriptome microarrays. (ersjournals.com)
Here we conjecture that spatially resolved gene expression, e.i., the transcriptome, can be used as an alternative to manual annotations. (ieee.org)
RNAs from these samples will be used for high-resolution expression profiling of the transcriptome using whole-genome tiling arrays, RNA ligase mediated Rapid Amplification of cDNA ends, RT-PCR and cDNA library construction. (encodeproject.org)
Previous transcriptome studies were mostly performed with high throughput microarray or Serial Analysis of Gene Expression (SAGE) approaches. (biomedcentral.com)
Information regarding the meiotic transcriptome should provide valuable clues about global expression patterns and detailed gene activities. (elsevier.com)
Equine Skeletal Muscle Transcriptome Identifies Novel Functional Responses To Exercise Training: Exercise training in the Thoroughbred racehorse results in co-ordinate changes in gene expression of functional groups of genes related to metabolism, oxidative phosphorylation and muscle structure. (plusvital.com)
Genes with moderate to low expression heritability may explain a large proportion of complex trait heritability, but these genes are insufficiently captured in transcriptome-wide association studies (TWAS) partly due to the relatively small available reference datasets for developing expression genetic prediction models to capture the moderate to low genetically regulated components of gene expression. (bvsalud.org)

Methods and Results: Transcriptomes from the three plant species were sequenced, assembled, and annotated. (soton.ac.uk)

Here we describe a workflow that takes advantage of distant genomic resources and ingroup transcriptomes to select and jointly enrich long open reading frames (ORFs) and ultraconserved elements (UCEs) from genomic samples for integrative studies of microevolutionary and macroevolutionary dynamics. (datadryad.org)

We used Illumina® Next Generation Sequencing (NGS) technology to gain unbiased biological insight into the transcriptome of normal epithelial cells (MCF-10A) to nicotine exposure. (vt.edu)

Our transcriptome resource is expected to enhance future research employing this emerging model animal for regeneration research as well as for investigations in other areas including developmental biology, stem cell biology, and cancer research. (elsevier.com)

In this study, we sought to quantify the astrocytic AMPAR transcriptome during brain development and with respect to selected brain regions. (nih.gov)

They also sequenced the transcriptome of the most devastating Striga species. (phys.org)
The cell isolation method and transcriptome analysis techniques can be adapted to other cell types and plant species and have broad application potential in plant science . (bvsalud.org)

Altogether, this study provides a deep understanding of the cellular mechanisms of transcriptome variation and of the landscape of functional variants in the human genome. (kb.se)
This study represents the most comprehensive analysis of the drought-response transcriptome of chickpea available to date. (icarda.org)
In this study, the floral transcriptome of Aspidistra saxicola was obtained by using NGS. (datadryad.org)
The present study was designed to generate high resolution transcriptome datasets for early SE providing the way for future research to understand the underlying molecular mechanisms that regulate this process. (reading.ac.uk)

hBMSC-HLCs possess a hepatic transcriptome profile and express hepatic-specific genes in vitro and in vivo , which might be useful for future clinical applications. (medsci.org)

To dissect the molecular mechanisms underlying DT in rice, deep transcriptome sequencing was used to investigate transcriptome differences among a DT introgression line H471, the DT donor P28, and the drought-sensitive, recurrent parent HHZ under drought stress. (biomedcentral.com)

We conducted an intensive transcriptome analysis of P. waltl using RNA-sequencing to build and annotate gene models. (elsevier.com)

mRNA sequencing was used in the transcriptome profiling of hBMSC-HLCs, with hBMSCs and HHs as controls. (medsci.org)

Liposomal Dox (Doxlipo) has been clinically approved for the treatment of breast cancer due to reduced systematical toxicity and increased tumor targeting, yet the transcriptome-wide elucidation of the Doxlipo formulations remains elusive. (dovepress.com)
Applying this method to 13,313 transcriptomes, we constructed a pediatric cancer atlas to explore age-associated changes. (cdc.gov)

Conclusions The transcriptome information provided here will form the foundation for future research on genetic and epigenetic control of plant embryogenesis at a molecular level. (reading.ac.uk)
Isolation and Transcriptome Analysis of Plant Cell Types. (bvsalud.org)

Here, we aimed to clarify the transcriptome characteristics of hBMSC-HLCs for future clinical application. (medsci.org)
A patient-centric research initiative, consisting of oncologists, pathologists and other clinical, research, and technical personnel, studying the impact of embedding whole genome and transcriptome analysis into the clinical care of B.C. patients with advanced cancers. (bcgsc.ca)

Using next-generation sequencing to decipher the molecular mechanisms underlying aberrant rheumatoid arthritis synovial fibroblasts (RASF) activation, we performed transcriptome-wide RNA-seq and small RNA-seq on synovial fibroblasts from rheumatoid arthritis (RA) subject and normal donor. (mdpi.com)

Russet Norkotah and TXNS278 leaf and root transcriptomes were sequenced at two time points during growing season. (biomedcentral.com)

Metabolome and transcriptome of the interaction between Ustilago maydis and Fusarium verticillioides in vitro. (jic.ac.uk)

The major goal of pharmacogenomics research is the development of genotype or transcriptome-based predictive tests of drug efficacy or toxicity. (bvsalud.org)

Melanin biosynthesis genes were solely expressed in the cells of melanocytic origin, indicating the feasibility of using the PET approach for transcriptome comparison. (biomedcentral.com)
We used direct RNA sequencing to determine the transcriptome of SARS-CoV-2 grown in Vero E6 cells which is widely used to propagate the novel coronavirus. (biomedcentral.com)

Article: The effects of low dose 60 Co-gamma-radiation on radioresistance, mutagenesis, gene conversion, cell cycle and transcriptome profile in Saccharomyces cerevisiae Journal: International Journal of Low Radiation (IJLR) 2008 Vol.5 No.4 pp.290 - 309 Abstract: The underlying principles of low (stress)-dose Radiation-Induced Radioresistance (RIR) are inadequately understood. (inderscience.com)

This work provides a comprehensive overview of the sex-differential transcriptome and its importance to human evolution and human physiology in health and in disease. (biomedcentral.com)

Studies on biological traits, such as biomass yield, COG/ Clusters of orthologous group sugar accumulation, and stress tolerance, have focused on KOG transcriptome analysis (Kido et al. (deepdyve.com)

Anatomy22

Organisms38

Diseases2

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Phenomena and Processes90

Disciplines and Occupations5

Technology, Industry, Agriculture6

Information Science11

Health Care3

Effects of basic fibroblast growth factor on the expressions of angiogenic gene profile and cyclooxygenase-2 in brain microvascular endothelial cells. (1/4463)

Stress-dependent coordination of transcriptome and translatome in yeast. (2/4463)

Variation in dehydration tolerance, ABA sensitivity and related gene expression patterns in D-genome progenitor and synthetic hexaploid wheat lines. (3/4463)

Identification and classification of small RNAs in transcriptome sequence data. (4/4463)

The transcriptome of human monocyte subsets begins to emerge. (5/4463)

A focus on natural variation for abiotic constraints response in the model species Arabidopsis thaliana. (6/4463)

A marginal mixture model for selecting differentially expressed genes across two types of tissue samples. (7/4463)

Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNalpha antibody, in systemic lupus erythematosus. (8/4463)

Transcriptome

Gene Expression Profiling

Molecular Sequence Annotation

Sequence Analysis, RNA

Oligonucleotide Array Sequence Analysis

Expressed Sequence Tags

High-Throughput Nucleotide Sequencing

Gene Expression Regulation, Plant

Gene Library

Gene Ontology

Transcription, Genetic

Cluster Analysis

Sequence Analysis, DNA

Genes, Plant

RNA, Plant

RNA, Messenger

Databases, Genetic

Contig Mapping

Microarray Analysis

Computational Biology

Genomics

Proteome

Gene Regulatory Networks

Reverse Transcriptase Polymerase Chain Reaction

Gene Expression Regulation

Gene Expression Regulation, Bacterial

Genome

Genome, Plant

Stress, Physiological

Arabidopsis

Metabolic Networks and Pathways

Plant Roots

Molecular Sequence Data

Base Sequence

Gene Expression Regulation, Developmental

Reproducibility of Results

Alternative Splicing

DNA, Complementary

Plant Leaves

Phylogeny

Real-Time Polymerase Chain Reaction

RNA, Untranslated

RNA

Plant Proteins

Signal Transduction

RNA Isoforms

Metabolome

MicroRNAs

Transcription Factors

Flowers

Biosynthetic Pathways

Untranslated Regions

Genome, Human

Cicer

Microsatellite Repeats

Species Specificity

Evolution, Molecular

Multigene Family

Organ Specificity

Gene Expression Regulation, Fungal

Chromosome Mapping

Gene Expression

Software

Regulon

Models, Genetic

Host-Pathogen Interactions

RNA, Antisense

Principal Component Analysis

Databases, Nucleic Acid

Oryza sativa

Open Reading Frames

Plant Diseases

Exons

Polymorphism, Single Nucleotide

Arabidopsis Proteins

RNA, Small Untranslated

Droughts

Secondary Metabolism

Phenotype

Genome, Helminth