AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science
TracheaTracheal NeoplasmsTracheal DiseasesTracheal StenosisGuinea PigsMuscle, SmoothBronchiMuscle RelaxationLarynxIntubation, IntratrachealMuscle ContractionRespiratory SystemMucusTracheotomyBronchoscopyLungHistamineEpitheliumAirway ObstructionTracheitisSRS-AExocrine GlandsMethacholine CompoundsBronchial DiseasesNeurokinin ATracheostomyBronchial NeoplasmsSubstance PParasympatholyticsParasympathetic Nervous SystemVagus NerveTracheoesophageal FistulaLaryngeal NervesAtropineLaryngeal CartilagesAcetylcholineMucous MembraneTachykininsMucociliary ClearanceElectric StimulationFiber Optic TechnologyIsoproterenolAporphinesCapsaicinAirway ResistanceRespiratory MucosaCarbacholThyroid CartilageLaryngoscopyIndomethacinEsophageal AtresiaEncyclopedias as TopicVaginal FistulaFistulaEsophagus
Trachea
The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi.
Tracheal Neoplasms
Tracheal Diseases
Tracheal Stenosis
Guinea Pigs
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Muscle, Smooth
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Bronchi
The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.
Muscle Relaxation
That phase of a muscle twitch during which a muscle returns to a resting position.
Larynx
A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.
Intubation, Intratracheal
A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia.
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Respiratory System
The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.
Mucus
The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.
Tracheotomy
Surgical incision of the trachea.
Bronchoscopy
Endoscopic examination, therapy or surgery of the bronchi.
Lung
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Histamine
An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Epithelium
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Airway Obstruction
Any hindrance to the passage of air into and out of the lungs.
Tracheitis
SRS-A
A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)
Exocrine Glands
Glands of external secretion that release its secretions to the body's cavities, organs, or surface, through a duct.
Methacholine Compounds
A group of compounds that are derivatives of beta-methylacetylcholine (methacholine).
Bronchial Diseases
Neurokinin A
A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ B with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the BRONCHI.
Tracheostomy
Surgical formation of an opening into the trachea through the neck, or the opening so created.
Bronchial Neoplasms
Tumors or cancer of the BRONCHI.
Substance P
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
Parasympatholytics
Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.
Parasympathetic Nervous System
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
Vagus Nerve
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Tracheoesophageal Fistula
Abnormal passage between the ESOPHAGUS and the TRACHEA, acquired or congenital, often associated with ESOPHAGEAL ATRESIA.
Laryngeal Nerves
Branches of the VAGUS NERVE. The superior laryngeal nerves originate near the nodose ganglion and separate into external branches, which supply motor fibers to the cricothyroid muscles, and internal branches, which carry sensory fibers. The RECURRENT LARYNGEAL NERVE originates more caudally and carries efferents to all muscles of the larynx except the cricothyroid. The laryngeal nerves and their various branches also carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.
Atropine
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
Laryngeal Cartilages
The nine cartilages of the larynx, including the cricoid, thyroid and epiglottic, and two each of arytenoid, corniculate and cuneiform.
Acetylcholine
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Mucous Membrane
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
Tachykinins
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
Mucociliary Clearance
A non-specific host defense mechanism that removes MUCUS and other material from the LUNGS by ciliary and secretory activity of the tracheobronchial submucosal glands. It is measured in vivo as mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.
Electric Stimulation
Use of electric potential or currents to elicit biological responses.
Fiber Optic Technology
The technology of transmitting light over long distances through strands of glass or other transparent material.
Isoproterenol
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
Aporphines
Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES).
Capsaicin
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
Airway Resistance
Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.
Respiratory Mucosa
The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Carbachol
A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Thyroid Cartilage
The largest cartilage of the larynx consisting of two laminae fusing anteriorly at an acute angle in the midline of the neck. The point of fusion forms a subcutaneous projection known as the Adam's apple.
Laryngoscopy
Examination, therapy or surgery of the interior of the larynx performed with a specially designed endoscope.
Indomethacin
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Esophageal Atresia
Congenital abnormality characterized by the lack of full development of the ESOPHAGUS that commonly occurs with TRACHEOESOPHAGEAL FISTULA. Symptoms include excessive SALIVATION; GAGGING; CYANOSIS; and DYSPNEA.
Encyclopedias as Topic
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Vaginal Fistula
An abnormal anatomical passage that connects the VAGINA to other organs, such as the bladder (VESICOVAGINAL FISTULA) or the rectum (RECTOVAGINAL FISTULA).
Fistula
Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.
Esophagus
The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.

Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. (1/4621)

The c-myb gene encodes a sequence specific transactivator that is required for fetal hematopoiesis, but its potential role in other tissues is less clear because of the early fetal demise of mice with targeted deletions of the c-myb gene and incomplete of knowledge about c-myb's expression pattern. In the hematopoietic system, c-Myb protein acts on target genes whose expression is restricted to individual lineages, despite Myb's presence and role in multiple immature lineages. This suggests that c-Myb actions within different cell type-specific contexts are strongly affected by combinatorial interactions. To consider the possibility of similar c-Myb actions could extend into non-hematopoietic systems in other cell and tissue compartments, we characterized c-myb expression in developing and adult mice using in situ hybridization and correlated this with stage-specific differentiation and mitotic activity. Diverse tissues exhibited strong c-myb expression during development, notably tooth buds, the thyroid primordium, developing trachea and proximal branching airway epithelium, hair follicles, hematopoietic cells, and gastrointestinal crypt epithelial cells. The latter three of these all maintained high expression into adulthood, but with characteristic restriction to immature cell lineages prior to their terminal differentiation. In all sites, during fetal and adult stages, loss of c-Myb expression correlated strikingly with the initiation of terminal differentiation, but not the loss of mitotic activity. Based on these data, we hypothesize that c-Myb's function during cellular differentiation is both an activator of immature gene expression and a suppressor of terminal differentiation in diverse lineages.  (+info)

Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells. (2/4621)

To investigate which retinoid receptors are critical in the regulation by all-trans-retinoic acid (RA) of the mucin genes MUC2, MUC5AC and MUC5B in cultured normal human tracheobronchial epithelial (NHTBE) cells, we used pan-RAR-, pan-RXR- and RAR- isotype (alpha, beta and gamma)-selective agonists and RARalpha- and RARgamma-selective antagonists (RAR is RA receptor and RXR is retinoid X receptor). RAR-, RARalpha- and RARgamma-selective agonists strongly induced mucin mRNAs in a dose-dependent manner, while the RARbeta-selective retinoid only weakly induced mucin gene expression at very high concentrations (1 microM). The pan-RXR-selective agonist by itself did not induce mucin gene expression, but acted synergistically with suboptimal concentrations of the pan-RAR agonist. A retinoid with selective anti-activator-protein-1 activity only marginally induced mucin gene expression. The RARalpha antagonist strongly inhibited mucin gene induction and mucous cell differentiation caused by RA and by the RARalpha- and RARgamma-selective retinoids. In contrast, the RARgamma antagonist only weakly inhibited RARalpha-selective-retinoid-induced mucin gene expression, but completely blocked mucin gene expression induced by the RARgamma-selective retinoid. Our studies indicate that RARalpha is the major retinoid receptor subtype mediating RA-dependent mucin gene expression and mucous cell differentiation, but that the RARgamma isotype can also induce mucin genes. Furthermore these studies suggest that RARbeta is probably not (directly) involved in RA-induced mucin gene expression.  (+info)

Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea. (3/4621)

The ability of the M2 muscarinic receptor to mediate an inhibition of the relaxant effects of forskolin and isoproterenol was investigated in guinea pig ileum and trachea. In some experiments, trachea was first treated with 4-diphenylacetoxy-N-methylpiperidine (4-DAMP) mustard to inactivate M3 receptors. The contractile response to oxotremorine-M was measured subsequently in the presence of both histamine (10 microM) and isoproterenol (10 nM). Under these conditions, [[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5, 11-dihydro-6H-pyrido[2,3b]-[1,4]benzodiazepine-6-one (AF-DX 116) antagonized the contractile response to oxotremorine-M in a manner consistent with an M3 mechanism. However, when the same experiment was repeated using forskolin (4 microM) instead of isoproterenol, the response to oxotremorine-M exhibited greater potency and was antagonized by AF-DX 116 in a manner consistent with an M2 mechanism. We also measured the effects of pertussis toxin treatment on the ability of isoproterenol to inhibit the contraction elicited by a single concentration of either histamine (0.3 microM) or oxotremorine-M (40 nM) in both the ileum and trachea. Pertussis toxin treatment had no significant effect on the potency of isoproterenol for inhibiting histamine-induced contractions in the ileum and trachea. In contrast, pertussis toxin treatment enhanced the relaxant potency of isoproterenol against oxotremorine-M-induced contractions in the ileum but not in the trachea. Also, pertussis toxin treatment enhanced the relaxant potency of forskolin against oxotremorine-M-induced contractions in the ileum and trachea. We investigated the relaxant potency of isoproterenol when very low, equi-effective (i.e., 20-34% of maximal response) concentrations of either histamine or oxotremorine-M were used to elicit contraction. Under these conditions, isoproterenol exhibited greater relaxant potency against histamine in the ileum but exhibited similar relaxant potencies against histamine and oxotremorine-M in the trachea. Following 4-DAMP mustard treatment, a low concentration of oxotremorine-M (10 nM) had no contractile effect in either the ileum or trachea. Nevertheless, in 4-DAMP mustard-treated tissue, oxotremorine-M (10 nM) reduced the relaxant potency of isoproterenol against histamine-induced contractions in the ileum, but not in the trachea. We conclude that in the trachea the M2 receptor mediates an inhibition of the relaxant effects of forskolin, but not isoproterenol, and the decreased relaxant potency of isoproterenol against contractions elicited by a muscarinic agonist relative to histamine is not due to activation of M2 receptors but rather to the greater contractile stimulus mediated by the M3 receptor compared with the H1 histamine receptor.  (+info)

Kinetic analysis of drug-receptor interactions of long-acting beta2 sympathomimetics in isolated receptor membranes: evidence against prolonged effects of salmeterol and formoterol on receptor-coupled adenylyl cyclase. (4/4621)

The long-acting beta2 sympathomimetics salmeterol and formoterol have been presumed to exert their prolonged action either by binding to an accessory binding site ("exo-site") near the beta2 adrenoceptor or by their high affinity for beta2 adrenoceptors and correspondingly slow dissociation. Whereas most studies with salmeterol had been done in intact tissues, which have slow diffusion and compartmentation of drugs in lipophilic phases, that restrict drug access to the receptor biophase, we used purified receptor membranes from rat lung and disaggregated calf tracheal myocytes as model systems. Binding experiments were designed to measure the slow dissociation of agonists by means of delayed association of (-)-[125I]iodopindolol. Rat lung membranes were pretreated with high concentrations of agonists (salmeterol, formoterol, isoprenaline) before dissociation was induced by 50-fold dilution. Half-times of association of (-)-[125I]iodopindolol remained unchanged compared with untreated controls, indicating that dissociation of agonists occurred in less than 2 min. Adenylyl cyclase experiments were designed to determine the on and off kinetics of agonists to beta2 adrenoceptors by measuring the rate of receptor-induced cyclic AMP (cAMP) formation. Experiments were performed in tracheal membranes characterized by high Vmax values of cAMP formation. Adenylyl cyclase activation occurred simultaneously with the addition of the agonist, continued linearly with time for 60 min, and ceased immediately after the antagonist was added. Similarly, when receptor membranes were preincubated in a small volume with high salmeterol concentrations, there was a linear increase in cAMP formation, which was immediately interrupted by a 100-fold dilution of the reaction mixture. This militates against the exo-site hypothesis. On the other hand, dissociation by dilution was much less when membranes were preincubated with a large volume of salmeterol at the same concentration, indicating that physicochemical effects, and not exo-site binding, underlie its prolonged mode of action.  (+info)

The contribution of extraneuronal uptake to the trachea-blood vessel selectivity of beta-adrenoceptor stimulants in vitro in guinea-pigs. (5/4621)

1 The potencies relative to isoprenaline of isoetharine, tertiary butyl noradrenaline, salbutamol, orciprenaline, Me 506, rimiterol, fenoterol, carbuterol and terbutaline on isolated preparations of guinea-pig trachea and blood vessels (perfused hind limb) were determined. All the compounds were selective for trachea and selectivity values, i.e. relative potency on trachea divided by relative potency on hind limb, ranged from 2.3 to 21.4. 2 Responses to isoprenaline (the reference compound), tertiary butyl noradrenaline and isoetharine were potentiated on trachea by 50 muM phenoxybenzamine (PHB) and by other inhibitors of extraneuronal uptake (ENU). Under these conditions the selectivity values of all the compounds was close to unity. 3 Selectivity values were also close to unity if they were calculated from data obtained without ENU inhibition, provided that only those compounds not potentiated by PHB on trachea were used. 4 It is proposed that the trachea-blood vessel selectivity shown by beta-adrenoceptor stimulants can be caused by the influence of ENU upon them, rather than by their ability to distinguish between two beta2-adrenoceptors. 5 The suggestion that differences exist between beta2-adrenoceptors in respiratory and vascular smooth muscle is not supported by the in vitro experiments described.  (+info)

The cat lung strip as an in vitro preparation of peripheral airways: a comparison of beta-adrenoceptor agonists, autacoids and anaphylactic challenge on the lung strip and trachea. (6/4621)

1 A new in vitro preparation, the isolated lung strip of the cat, is described for investigating the direct effect of drugs on the smooth muscle of the peripheral airways of the lung. The preparation comprises a thin strip of lung parenchyma which can be mounted in a conventional organ bath for isometric tension recording. Its pharmacological responses have been characterized and compared with the isolated tracheal preparation of the cat. 2 The lung strip exhibited an intrinsic tone which was relaxed by catecholamines, aminophylline and flufenamate. It was contracted strongly by histamine, prostaglandin F2alpha, acetylcholine, compound 48/80, potassium depolarizing solution and alternating current field stimulation. In contrast, the cat trachea was unresponsive to histamine and prostaglandin F2alpha and did not exhibit an intrinsic tone. 3 (-)-Isoprenaline and (-)-adrenaline were much more potent in relaxing the lung strip than the trachea. The potency order of relaxation responses to isoprenaline, adrenaline and (+/-)-noradrenaline in the lung strip was isoprenaline greater than adrenaline greater than noradrenaline but in the trachea was isoprenaline greater than noradrenaline greater than or equal to adrenaline. 4 beta2-Adrenoceptor selective agonists salbutamol and terbutaline were more potent in the lung strip than the trachea, suggesting beta2-adrenoceptors predominated in the lung strip. Propranolol was equipotent in inhibiting isoprenaline relexations of the lung strip and trachea, whereas practolol was much less effective in inhibiting lung strip than trachea, further supporting a predominance of beta2-adrenoceptors in lung strip and beta1-adrenoceptors in trachea. 5 Strong Schultz-Dale type contractions were elicited in both lung strips and trachea by Ascaris lumbricoides antigen in actively sensitized cats. The initial phase of the contractile response of the lung strip following challenge was shown to be due to histamine release and was absent in the trachea. The delayed phase of the contraction which took several minutes to develop in both the mepyramine-treated lung strip and trachea was not due to prostaglandins E1, F2alpha or bradykinin, the probable mediator being slow reacting substance of anaphylaxis (SRS-A). 6 It is concluded that the isolated lung strip of the cat is useful as an in vitro model for investigating the effect of drugs on the smooth muscle of the peripheral airways of the lungs.  (+info)

Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: activation of BK(Ca) channels and inhibition of neurotransmitter release. (7/4621)

1. The aims of this study were to determine: (1) whether vasoactive intestinal peptide (VIP) regulates cholinergic and 'sensory-efferent' (tachykininergic) 35SO4 labelled mucus output in ferret trachea in vitro, using a VIP antibody, (2) the class of potassium (K+) channel involved in VIP-regulation of cholinergic neural secretion using glibenclamide (an ATP-sensitive K+ (K(ATP)) channel inhibitor), iberiotoxin (a large conductance calcium activated K+ (BK(ca)) channel blocker), and apamin (a small conductance K(ca) (SK(ca)) channel blocker), and (3) the effect of VIP on cholinergic neurotransmission using [3H]-choline overflow as a marker for acetylcholine (ACh) release. 2. Exogenous VIP (1 and 10 microM) alone increased 35SO4 output by up to 53% above baseline, but suppressed (by up to 80% at 1 microM) cholinergic and tachykininergic neural secretion without altering secretion induced by ACh or substance P (1 microM each). Endogenous VIP accounted for the minor increase in non-adrenergic, non-cholinergic (NANC), non-tachykininergic neural secretion, which was compatible with the secretory response of exogenous VIP. 3. Iberiotoxin (3 microM), but not apamin (1 microM) or glibenclamide (0.1 microM), reversed the inhibition by VIP (10 nM) of cholinergic neural secretion. 4. Both endogenous VIP (by use of the VIP antibody; 1:500 dilution) and exogenous VIP (0.1 microM), the latter by 34%, inhibited ACh release from cholinergic nerve terminals and this suppression was completely reversed by iberiotoxin (0.1 microM). 5. We conclude that, in ferret trachea in vitro, endogenous VIP has dual activity whereby its small direct stimulatory action on mucus secretion is secondary to its marked regulation of cholinergic and tachykininergic neurogenic mucus secretion. Regulation is via inhibition of neurotransmitter release, consequent upon opening of BK(Ca) channels. In the context of neurogenic mucus secretion, we propose that VIP joins NO as a neurotransmitter of i-NANC nerves in ferret trachea.  (+info)

Anaphylactic bronchoconstriction in BP2 mice: interactions between serotonin and acetylcholine. (8/4621)

1. Immunized BP2 mice developed an acute bronchoconstriction in vivo and airway muscle contraction in vitro in response to ovalbumin (OA) and these contractions were dose dependent. 2. Methysergide or atropine inhibited OA-induced bronchoconstriction in vivo and airway muscle contraction in vitro. 3. Neostigmine potentiated the OA-induced bronchoconstriction in vivo and airway muscle contraction in vitro of BP2 mice. This potentiation was markedly reduced by the administration of methysergide or atropine and when the two antagonists were administered together, the responses were completely inhibited. 4. Neostigmine also potentiated the serotonin (5-HT)- and acetylcholine (ACh)-induced bronchoconstriction and this potentiation was significantly reversed by atropine. 5. These results indicate that OA provokes a bronchoconstriction in immunized BP2 mice by stimulating the release of 5-HT, which in turn acts via the cholinergic mediator, ACh.  (+info)

Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth...
TY - JOUR. T1 - Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells. AU - Lee, I-Ta. AU - Wang, Shyi Wu. AU - Lee, Chiang Wen. AU - Chang, Chia Chi. AU - Lin, Chih Chung. AU - Luo, Shue Fen. AU - Yang, Chuen Mao. PY - 2008/10/1. Y1 - 2008/10/1. N2 - Heme oxygenase (HO)-1 is a stress-inducible rate-limiting enzyme in heme degradation that confers cytoprotection against oxidative injury and provides a vital function in maintaining tissue homeostasis. Increasing reports have indicated that lipoteichoic acid (LTA) exerts as LPS as an immune system-stimulating agent and plays a role in the pathogenesis of severe inflammatory responses induced by Gram-positive bacterial infection. We report that LTA is an inducer of HO-1 expression mediated through the signaling pathways in human tracheal smooth muscle cells (HTSMCs). LTA-induced HO-1 protein levels, mRNA expression, and promoter activity were attenuated by ...
https://tmu.pure.elsevier.com/en/publications/lipoteichoic-acid-induces-ho-1-expression-via-the-tlr2myd88c-srcn
Vardenafil inhibiting parasympathetic function of tracheal smooth muscle<...
TY - JOUR. T1 - Vardenafil inhibiting parasympathetic function of tracheal smooth muscle. AU - Lee, Fei Peng. AU - Chao, Pin Zhir. AU - Wang, Hsing Won. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Background: Levitra, a phosphodiesterase-5 (PDE5) inhibitor, is the trade name of vardenafil. Nowadays, it is applied to treatment of erectile dysfunction. PDE5 inhibitors are employed to induce dilatation of the vascular smooth muscle. The effect of Levitra on impotency is well known; however, its effect on the tracheal smooth muscle has rarely been explored. When administered for sexual symptoms via oral intake or inhalation, Levitra might affect the trachea. Methods: This study assessed the effects of Levitra on isolated rat tracheal smooth muscle by examining its effect on resting tension of tracheal smooth muscle, contraction caused by 10-6 M methacholine as a parasympathetic mimetic, and electrically induced tracheal smooth muscle contractions. Results: The results showed that adding methacholine to the ...
https://tmu.pure.elsevier.com/en/publications/vardenafil-inhibiting-parasympathetic-function-of-tracheal-smooth
Regulation by calcium of proliferation and morphology of normal human tracheobronchial epithelial cell cultures | Journal of...Regulation by calcium of proliferation and morphology of normal human tracheobronchial epithelial cell cultures | Journal of...
Human tracheobronchial epithelial cells have been serially passaged in serum-free medium. This serum-free model was employed to investigate the effects of different concentrations of Ca2+ (0.1, 1.0 and 2.0 mM) on multiplication and morphology of the cells. The responses were analysed in terms of growth kinetics, histochemical and ultrastructural alterations. Culturing of the cells in high Ca2+ (1.0-2.0 mM) medium stimulated cell multiplication characterized by increased colony forming efficiency, greater number of cells per colony and cell population doublings per day. Additionally, the high Ca2+ concentrations induced proliferation in cultures grown to confluency in low Ca2+ (0.1 mM) medium. Cells propagated in low Ca2+ medium consisted of relatively heterogeneous cell populations, with most cells staining positive with periodic acid-Schiff (PAS) reagent. Ultrastructurally the cells exhibited secretory vesicles and microvilli on their surfaces, small desmosomes and intercellular interdigitation ...
http://jcs.biologists.org/content/96/3/509
Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction | Respiratory...Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction | Respiratory...
In addition to their proliferative and differentiating effects, several growth factors are capable of inducing a sustained airway smooth muscle (ASM) contraction. These contractile effects were previously found to be dependent on Rho-kinase and have also been associated with the production of eicosanoids. However, the precise mechanisms underlying growth factor-induced contraction are still unknown. In this study we investigated the role of contractile prostaglandins and Rho-kinase in growth factor-induced ASM contraction. Growth factor-induced contractions of guinea pig open-ring tracheal preparations were studied by isometric tension measurements. The contribution of Rho-kinase, mitogen-activated protein kinase (MAPK) and cyclooxygenase (COX) to these reponses was established, using the inhibitors Y-27632 (1 μM), U-0126 (3 μM) and indomethacin (3 μM), respectively. The Rho-kinase dependency of contractions induced by exogenously applied prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) was
https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-6-85
Primary Malignancy Lung and trachea | HDR UK Phenotype Library
Primary care Disease Readcode Medcode ReadcodeDescr Category Primary Malignancy_Lung and trachea B220100 103946.0 Malignant neoplasm of mucosa of trachea Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B220.00 15221.0 Malignant neoplasm of trachea Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B220z00 37810.0 Malignant neoplasm of trachea NOS Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B221000 17391.0 Malignant neoplasm of carina of bronchus Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B221100 33444.0 Malignant neoplasm of hilus of lung Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B221.00 12870.0 Malignant neoplasm of main bronchus Diagnosis of Primary Malignancy_Lung and trachea Primary Malignancy_Lung and trachea B221z00 21698.0 Malignant neoplasm of main bronchus NOS Diagnosis of Primary Malignancy_Lung and
https://portal.caliberresearch.org/phenotypes/kuan-pri-lung-amupxu3c33bfegnj3ljian
WFIRM scientists 3D bioprint multi-material tracheal tissue - World Stem Cell SummitWFIRM scientists 3D bioprint multi-material tracheal tissue - World Stem Cell Summit
People have tried other materials, but the problem has been they were using just one material that is not strong enough to hold the airways open and does not provide the flexibility needed, explained Sean Murphy, PhD, lead author and assistant professor of regenerative medicine at WFIRM. Our bioprinting method provides a combination of flexibility and strength needed to mimic native tracheal tissue.. Down the line, bioprinted tracheal tissue could be used to treat tracheal stenosis, a rare condition or symptom that causes the stiffening and narrowing of the trachea and can lead to death. Presently, treatments for the condition are limited and present their own challenges. Being able to 3D bioprint a patient specific tracheal tissue could therefore present a new and innovative solution.. The novel approach developed by the WFIRM team combines three key areas: patient-specific medical imaging, hydrogels embedded with differentiated cells and polymeric scaffolding with biomechanical-inspired ...
https://www.worldstemcellsummit.com/2019/12/12/wfirm-scientists-3d-bioprint-multi-material-tracheal-tissue/
Attachment of Mycoplasma pneumoniae to hamster tracheal organ...Attachment of Mycoplasma pneumoniae to hamster tracheal organ...
Attachment of Mycoplasma pneumoniae to hamster tracheal organ cultures, tracheal outgrowth monolayers, human erythrocytes, and WiDr human tissue culture cells.:
https://www.mysciencework.com/publication/show/attachment-of-mycoplasma-pneumoniae-to-hamster-tracheal-organ-cultures-tracheal-outgrowth-monolayers-human-erythrocytes-and-widr-human-tissue-culture-cells
DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo | DevelopmentDPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo | Development
We report that DPP signaling is required for directed tracheal cell migration during Drosophila embryogenesis. The failure of tracheal cells to receive the DPP signal from adjacent dorsal and ventral cells results in the absence of dorsal and ventral migrations. Ectopic DPP signaling can reprogram cells in the center of the placode to adopt a dorsoventral migration behavior. The effects observed in response to ectopic DPP signaling are also observed upon the tracheal-specific expression of a constitutive active DPP type I receptor (TKV(Q253D)), indicating that the DPP signal is received and transmitted in tracheal cells to control their migration behavior. DPP signaling determines localized gene expression patterns in the developing tracheal placode, and is also required for the dorsal expression of the recently identified BRANCHLESS (BNL) guidance molecule, the ligand of the BREATHLESS (BTL) receptor. Thus, DPP plays a dual role during tracheal cell migration. It is required to control the ...
https://dev.biologists.org/content/124/14/2741?ijkey=9b322f5218a83d2c8b090232a993e407a7b9f6ba&keytype2=tf_ipsecsha
IL-4 inhibits calcium transients in bovine trachealis cells by a ryano by Michael F. Ethier and John M. MadisonIL-4 inhibits calcium transients in bovine trachealis cells by a ryano by Michael F. Ethier and John M. Madison
IL-4 and IL-13 have important roles in the pathogenesis of asthma. A novel finding was that brief exposure of airway smooth muscle cells to IL-4 inhibited carbachol-stimulated calcium transients. We hypothesized that IL-4 inhibits transients by decreasing calcium store content and tested this by measuring the effects of IL-4 on transients induced by a nonspecific ionophore. Bovine trachealis cells were loaded with fura 2-AM, and cytosolic calcium concentrations ([Ca2+]i) were measured in single cells by digital microscopy. Stimulation (S1) with carbachol (10 microM) caused rapid, transient increases in [Ca2+]i to 1299 +/- 355 nM (n=5). After recovery of calcium stores, stimulation (S2) of the same cells with ionomycin (10 microM), in the absence of extracellular calcium, also increased [Ca2+]i to give S2/S1 ratio of 1.03 +/- 0.29. However, after 20 min of IL-4 (50 ng/ml), but not IL-13, ionomycin transients were decreased to 0.50 +/- 0.16 (S2/S1, P=0.02, n=6). IL-4 did not inhibit transients with
http://escholarship.umassmed.edu/oapubs/563/
Airway epithelial cells modulate cholinergic neurotransmission in dog trachea<...
TY - JOUR. T1 - Airway epithelial cells modulate cholinergic neurotransmission in dog trachea. AU - Aizawa, H.. AU - Matsumoto, K.. AU - Shigyo, M.. AU - Inoue, H.. AU - Koto, H.. AU - Takata, S.. AU - Hara, N.. PY - 1994/7. Y1 - 1994/7. N2 - We investigated the effects of epithelial cells on excitatory cholinergic neurotransmission in dog trachea, to shed more light on the role of airway epithelial cells in regulating airway responsiveness. Airway epithelial cells were prepared by an enzymatic dissociation of the tracheal mucosa using protease-free collagenase. Tracheal smooth muscle contractions evoked by electrical field stimulation (EFS) or acetylcholine (ACh) were measured before and after the application of epithelial cells. Isolated and dispersed epithelial cells (3 × 105 cells/ml) suppressed the amplitude of the twitch-like contractions evoked by EFS in the combined presence of guanethidine sulfate (10-6m) and indomethacin (10-5m). In contrast, epithelial cells did not affect the ...
https://kyushu-u.pure.elsevier.com/en/publications/airway-epithelial-cells-modulate-cholinergic-neurotransmission-in
XC-407A Advanced Human Trachea Intubation Model Xincheng Scientific Industries Co., Ltd.
XC-407A Advanced Human Trachea Intubation Model-Xincheng Scientific Industries Co., Ltd. -ProductName:AdvancedHumanTracheaIntubationModelProductNo:XC-407AMaterial:PVCDescription:Features:1)UpgradedfromXC-4072)Neckbackwardfunction,morerealisticsimulationofendotrachealintubationtechniqueandt
http://www.xinch.com/product/353.html
On the Measurement of Vascular and Respiratory Smooth Muscle Responses in vitro - ScienceOpenOn the Measurement of Vascular and Respiratory Smooth Muscle Responses in vitro - ScienceOpen
The action of drugs on circular smooth muscle from rabbit renal artery, renal vein, mesenteric vein, inferior vena cava, guinea pig bronchus, and mouse trachea was studied using an inexpensive modification of the method of Bevan, Nielsen and Ovvman, and Bevan and Osher. Two 30-gauge disposable stainless steel hypodermic needles supported the tissue rings in a standard 10-ml isolated muscle bath. All the blood vessels contracted to norepinephrine, histamine, and KCl. The veins, unlike the renal artery, did not respond maximally to KCl and did not contract at all to serotonin. The guinea pig bronchi contracted to carbachol, histamine, and KCl and relaxed to isoproterenol. The mouse trachea contracted maximally to carbachol, did not contract to histamine, and contracted to 50% of maximum in response to KCl. Thus, standard isolated tissue baths can be inexpensively adapted for the study of relatively small blood vessels and airways (about 1 mm in diameter).
https://www.scienceopen.com/document?vid=e78ce58b-fdaa-43c5-a028-600a56eb2dc6
Developmental Morphology of Human Fetal Trachea - MAHE Digital RepositoryDevelopmental Morphology of Human Fetal Trachea - MAHE Digital Repository
Histologically the trachea is made up of mucosa, submucosa, hyaline cartilage and adventitia. Therefore the study of histogenesis of the fetal trachea provides not only the information on the functional morphology of the organ, but also gives a baseline in the investigations and management of pre and neonatal pathological conditions. The present study was carried out on 15 human fetuses of known gestational age of all trimesters in the department of Anatomy in KMC Manipal. The transverse section of trachea was taken. The sections were stained using Hematoxylin and Eosin and were observed under light microscope. The microscopic anatomy of the trachea was observed at different GA and the changes were observed. At first trimester the trachea was lined by pseudostratified columnar epithelium without any goblet cells. Incomplete rings of hyaline cartilage were also observed .The cellular components of the hyaline cartilage were predominant while the amount of ground substance was comparatively less. ...
http://eprints.manipal.edu/140769/
Repositorio da Producao Cientifica e Intelectual da Unicamp: Mechanisms of relaxant activity of the nitric oxide-independent...Repositorio da Producao Cientifica e Intelectual da Unicamp: Mechanisms of relaxant activity of the nitric oxide-independent...
The soluble guanylyl cyclase is expressed in airway smooth muscle, and agents that stimulate this enzyme activity cause airway smooth muscle relaxation and bronchodilation. The compound 5-Cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-pyrimidin-4-ylamine (BAY 41-2272) is a potent nitric oxide (NO)-independent soluble guanylyl cyclase stimulator, but little is known about its effects in airway smooth muscle. Therefore, this study aimed to investigate the mechanisms underlying the relaxations of rat tracheal smooth muscle induced by BAY 41-2272. Tracheal rings were mounted in 10-ml organ baths for isometric force recording. BAY 41-2272 concentration-dependently relaxed carbachol-precontracted tracheal rings (pEC(50) = 6.68 +/- 0.14). Prior incubation with the NO synthesis inhibitor L-NAME (100 mu M) or the soluble guanylyl cyclase inhibitor ODQ (10 mu M) caused significant rightward shifts in the concentration-response curves to BAY 41-2272. Sodium nitroprusside caused ...
http://repositorio.unicamp.br/jspui/handle/REPOSIP/53530
Tracheobronchial airway obstruction - RightDiagnosis.comTracheobronchial airway obstruction - RightDiagnosis.com
List of 10 disease causes of Tracheobronchial airway obstruction, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Tracheobronchial airway obstruction.
http://www.rightdiagnosis.com/sym/tracheobronchial_airway_obstruction.htm
Plus itPlus it
Tumor necrosis factor-α (TNFα) stimulates the expression of intercellular adhesion molecule-1 (ICAM-1) by activating the transcription factor nuclear factor-κB (NF-κB) in human airway smooth muscle (ASM) cells. This study characterizes the receptor involved as well as critical downstream signaling events mediating cytokine-induced NF-κB activation and ICAM-1 expression. TNFα stimulation for 1 to 4 h induced ICAM-1 expression in human ASM cells. This rapid TNFα-induced ICAM-1 expression enhanced T-lymphocyte adhesion to ASM cells, which was inhibited by anti-ICAM-1 antibodies. Using immunostaining, we demonstrated that TNFα receptors TNFR1 and TNFR2 are expressed on native human tracheal smooth muscle. Treatment of cells with htr-9, an antibody that specifically activates TNFR1, also stimulated expression of ICAM-1 mRNA and protein. Utr-1, a blocking antibody to TNFR2, did not affect TNFα-mediated ICAM-1 expression. Both TNFα and htr-9 increased luciferase activity in ASM cells ...
http://molpharm.aspetjournals.org/content/58/1/237
Plus itPlus it
Ro 25-1553, a cyclic peptide analog of vasoactive intestinal peptide (VIP), was designed to overcome many of the deficiencies inherent in this natural neuropeptide. On isolated guinea pig tracheal smooth muscle, Ro 25-1553 produces concentration-dependent relaxation of contractile responses to a number of different spasmogens. Depending on the contractile stimulus, Ro 25-1553 is 24 to 89 times more potent than VIP as a relaxant of guinea pig trachea. The high potency of Ro 25-1553 extends to studies on isolated, histamine-contracted, human bronchial smooth muscle, where Ro 25-1553 exhibits a 390-fold enhancement over native VIP and is more potent than other bronchodilating drugs, such as the beta 2-adrenoceptor agonists isoproterenol and salbutamol. Ro 25-1553 was shown to displace the radioligand 125I-VIP from rat forebrain membranes with an IC50 value of 4.98 nM, thereby demonstrating that it acts at a VIP receptor. In addition, when tested in a battery of 40 other binding assays (e.g., ...
http://jpet.aspetjournals.org/content/270/3/1282
Investigation of the Mechanical Properties of the Human Tracheal CartilageInvestigation of the Mechanical Properties of the Human Tracheal Cartilage
Background: The tracheal cartilage plays an important role in maintaining the mechanical stability of the trachea, as it keeps the trachea open and prevents its collapse under the negative pressures of the respiratory cycle. This study aimed to evaluate and compare the mechanical properties of cartilage specimens from the cranial and caudal regions of the human trachea and compare the results with respect to age and sex of the subjects. Materials and Methods: After obtaining human trachea samples from braindead, organ-donating patients and storing them in appropriate conditions, the prepared cartilage samples from the cranial and caudal regions of the trachea were subjected to uniaxial tension and stress relaxation experiments to obtain the corresponding Youngs modulus and relaxation percentage values, respectively. The results were compared in terms of the position (cranial or caudal) in the trachea, and age and sex of the patients. Results: Based on the results, no statistically significant effect of
http://www.tanaffosjournal.ir/article_240177.html
Dendritic cells in the mucosa of the human trachea are not regularly found in the first year of life | ThoraxDendritic cells in the mucosa of the human trachea are not regularly found in the first year of life | Thorax
In this study human tissue of the respiratory tract was examined retrospectively. It was extremely difficult to collect an adequate number of cases who had died an acute death since necroscopic examination in these cases is rare. The data presented support the findings of other investigators who described DCs in human lung tissue and, for the first time, yield information on the initial occurrence and frequency of mature DCs in the human tracheal mucosa.. Animal data suggest an increase in bone marrow progenitor cells of DC and the immigration of these cells into different lung compartments.26 27 Since it has been shown that the number of DCs in the respiratory mucosa increases faster than neutrophil granulocytes after bacterial stimulation, local stimulation and ongoing proliferation might also be involved.28 Interestingly, our data are in line with recent findings in very young mice in whom few DCs were found in the airways. Resistance to pulmonary allergen sensitisation of these mice could be ...
https://thorax.bmj.com/content/56/6/427
Tissue engineered cartilage generated from human trachea using DegraPol® scaffold - Zurich Open Repository and ArchiveTissue engineered cartilage generated from human trachea using DegraPol® scaffold - Zurich Open Repository and Archive
Objective: To date numerous attempts have been undertaken to conquer the challenging problem of reconstructing long segmental tracheal defects, as yet without lasting success. Recently, employing concepts of tissue engineering in animals, cartilage-like constructs were transplanted in vivo. However, both the feasibility of fabricating tracheal replacements and the use of human tracheal chondrocytes (HTC) for tissue engineering are still under investigation. In this study, we optimized isolation and cultivation techniques for human tracheal cartilage, assessing the feasibility of seeding these cells onto a novel, three-dimensional (3-D) polyester-urethane polymer (DegraPol®). Methods: Human tracheal cartilage was harvested from the trachea of lung donors, digested in 0.3% collagenase II, and the condrocytes serially passaged every 7-9 days. Cells were also cultivated over agar plate during the total 6-8 weeks expansion phase. Thereafter, chondrocytes were seeded onto DegraPol® (pore sizes ...
https://www.zora.uzh.ch/id/eprint/153895/
Primary Bronchial/Tracheal Epithelial Cells; Normal, Human ATCC ®Primary Bronchial/Tracheal Epithelial Cells; Normal, Human ATCC ®
ATCC ® Normal Human Primary Bronchial/Tracheal Epithelial Cells, when grown in Airway Epithelial Cell Basal Media supplemented with Bronchial/Tracheal Epithelial Cell Growth Kit components, provide an ideal cell system to propagate bronchial/tracheal epithelial cells in serum-free conditions. The cells are cryopreserved at the second passage to ensure the highest viability and plating efficiency. ATCC ® Primary Cell Solutions™ cells, media, supplements and reagents are quality tested together to guarantee optimum performance and reliability.
https://www.atcc.org/en/Products/Cells_and_Microorganisms/Human_Primary_Cells/Alphanumeric/PCS-300-010.aspx
Endothelin-1 potentiates cholinergic neurotransmission in rat trachea via ETA and ETB receptors<...
TY - GEN. T1 - Endothelin-1 potentiates cholinergic neurotransmission in rat trachea via ETA and ETB receptors. AU - Knott, P.G.. AU - Henry, Peter. AU - Goldie, Roy. PY - 1995. Y1 - 1995. M3 - Conference paper. VL - 2. SP - 99. BT - 29th Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologist. PB - Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists. CY - Sydney Australia. T2 - Endothelin-1 potentiates cholinergic neurotransmission in rat trachea via ETA and ETB receptors. Y2 - 1 January 1995. ER - ...
https://research-repository.uwa.edu.au/en/publications/endothelin-1-potentiates-cholinergic-neurotransmission-in-rat-tra
Brooklyn Vet Group
TRACHEAL COLLAPSE. Tracheal collapse is a progressive degenerative disorder of the tracheal cartilage, which results in a reduction of the luminal diameter of the trachea. The normal ring-shaped cartilages become C-shaped and flattened. The trachea becomes stretched and floppy, and to varying degrees falls down and obstructs the tracheal lumen. The normal diameter of the trachea is maintained by rigid hyaline cartilage rings. The loss of tone in the cartilage causes the collapse but it is unknown why exactly this loss in tone occurs. Dogs with tracheal collapse have abnormal cartilage rings that collapse with changes in tracheal pressure. As the trachea collapses, there is irritation and trauma to the trachea itself, which induces coughing and this induces even more collapse and further coughing.. CLINICAL SIGNS. Toy breeds such as Yorkshire terriers, Chihuahuas, Pomeranians, and Poodles are predisposed and clinical signs typically occur when dogs are middle aged (4-8 years). The most common ...
http://www.brooklynvetgroup.com/1/0/137/Tracheal_Collapse.htm
PLOS ONE: Mast Cells Present Protrusions into Blood Vessels upon Tracheal Allergen Challenge in MicePLOS ONE: Mast Cells Present Protrusions into Blood Vessels upon Tracheal Allergen Challenge in Mice
Mast cells (MC) and myeloid dendritic cells (DC) act proximally in detecting and processing antigens and immune insults. We sought to understand their comparative dynamic behavior with respect to the airway epithelium in the steady state and in response to an allergic stimulus in mouse trachea. We devised methods to label MC in living trachea and to demonstrate that MC and DC occupy distinct layers of the tracheal mucosa, with DC being closer to the lumen. DC numbers doubled after allergen challenge, but MC numbers remained stable. MC and DC migrated minimally in either steady state or allergen-challenge conditions, and their interactions with one another appeared to be stochastic and relatively infrequent. While DC, unlike MC, exhibited probing behaviors involving dendrites, these projections did not cross the epithelium into the airway lumen. MC typically were located too far from the epithelial surface to contact the tracheal lumen. However, MC had protrusions toward and into blood vessels, likely to
https://journals.plos.org/plosone/article/authors?id=10.1371/journal.pone.0118513
AID 79681 - Negative log of the concentration producing 50% of the maximum effect was measured in guinea pig trachea - PubChemAID 79681 - Negative log of the concentration producing 50% of the maximum effect was measured in guinea pig trachea - PubChem
BioAssay record AID 79681 submitted by ChEMBL: Negative log of the concentration producing 50% of the maximum effect was measured in guinea pig trachea.
https://pubchem.ncbi.nlm.nih.gov/bioassay/79681
Vertebrate trachea - wikidoc
The tracheartes, or windpipe, is a tube that has an inner diameter of about 20-25 mm and a length of about 10-16cm. It commences at the larynx(at the level vertebral level of C6 in humans) and bifurcates into the primary (main) bronchi (at the vertebral level of T4/T5 in humans) in mammals, and from the pharynx to the syrinx in birds, allowing the passage of air to the lungs. It is lined with pseudostratified ciliated columnar epithelium cells with mucosae goblet cells which produce mucus. This lines the cells of the trachea to trap inhaled foreign particles which the cilia then waft upwards towards their larynx and then the pharynx where it can then be swallowed into the stomach. In humans there are about 15 - 20 incomplete C-shaped cartilaginous rings which reinforces the anterior and lateral sides of the trachea to protect and maintain the airway open. There is a piece of smooth muscle connecting the ends off the incomplete cartilaginous rings called the Trachealis muscle. This contracts ...
http://es.wikidoc.org/index.php/Vertebrate_trachea
Difference between revisions of Artificial Trachea, by Chris Carr - OpenWetWareDifference between revisions of Artificial Trachea, by Chris Carr - OpenWetWare
The trachea, also known as the windpipe, is the passage way that leads air to your lungs. It is made up of cartilage, muscle and connective tissue. Tracheas are often around 4 inches long which are comprised of approximately 20 cartilage rings. On the inside lining of the trachea is a mucus membrane that is able to catch harmful airborne particles and bacteria before it reaches your lungs. Swallowing and sneezing are ways of removing these particles [4C]. Breathing involves two main steps; oxygen enters the body when you breathe in and carbon dioxide leaves the body when you exhale. When someone takes a breath, oxygen goes through the nose and mouth down their trachea. From here the trachea splits up into two bronchi tubes which lead to the left and right lung. Next the oxygen travels through the smaller branches, bronchioles, to millions of small alveoli located throughout the lungs. Alveoli are small sacs in the lungs that allow for the exchange of gases with the blood stream. Here oxygen is ...
https://openwetware.org/wiki/?title=Artificial_Trachea%25252C_by_Chris_Carr&diff=prev&oldid=691387
PPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma TherapyPPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma Therapy
In asthma, the increase in airway smooth muscle (ASM) can contribute to inflammation, airway wall remodeling and airway hyperresponsiveness (AHR). Targetting peroxisome proliferator-activated receptor |i|γ|/i| (PPAR|i|γ|/i|), a receptor upregulated in ASM in asthmatic airways, may provide a novel approach to regulate these contributions. This review summarises experimental evidence that PPAR|i|γ|/i| ligands, such as rosiglitazone (RGZ) and pioglitazone (PGZ), inhibit proliferation and inflammatory cytokine production from ASM |i|in vitro|/i|. In addition, inhaled administration of these ligands reduces inflammatory cell infiltration and airway remodelling in mouse models of allergen-induced airways disease. PPAR|i|γ|/i| ligands can also regulate ASM contractility, with acute treatment eliciting relaxation of mouse trachea |i|in vitro |/i|through a PPAR|i|γ|/i|-independent mechanism. Chronic treatment can protect against the loss of bronchodilator sensitivity to |i|β|
https://www.hindawi.com/journals/ppar/2012/809164/
LOX-DB - LipOXygenases DataBase - LiteratureLOX-DB - LipOXygenases DataBase - Literature
The purpose of our studies was to examine differentiation-dependent expression of 15-lipoxygenase (15-LO) and prostaglandin H synthase (PGHS) isoforms in cultured normal human tracheobronchial epithelial cells. In the presence of retinoic acid (RA) the cultures differentiated into a mucociliary epithelium. When cultured in RA-depleted media, the cultures differentiated into a squamous epithelium. In the absence of RA the cultures did not express 15-LO or either of the PGHS isoforms. The PGHS-1 isoform was not expressed in RA-sufficient cultures, but both PGHS-2 messenger RNA (mRNA) and protein were strongly expressed, and prostaglandin E2 (PGE2) was produced during the predifferentiation phase. No PGHS-2 expression or PGE2 could be detected in fully differentiated mucociliary cultures. 15-LO showed the opposite expression pattern: neither mRNA nor protein were detected during the predifferentiation stage, but both were strongly expressed once mucous differentiation had occurred. Cytosolic ...
http://www.glycosciences.de/spec/lox-db/show-literature.php?lit_id=230
Plus itPlus it
The present study represents the first electrophysiological and cellular evaluation of parasympathetic ganglionic neurons from tracheas and bronchi of mice. Data reported here regarding membrane properties such as the resting membrane potential, input resistance, and time constant of mouse airway neurons were within the range of those recorded in vitro for guinea pig (16), human (9), and ferret airway parasympathetic neurons (1), and in vivo for cat tracheal ganglion neurons (11). Although membrane properties of airway parasympathetic ganglionic neurons from human and other laboratory animals were similar, this may not necessarily indicate that these cells have a similar level of integration in the mammalian airways.. In this study, clusters of neurons (ganglia) were located on the mouse trachea and bronchi and could be investigated directly using intracellular microelectrodes. Thus far, it has been reported that parasympathetic neurons located in the intrinsic airway ganglia have anatomical and ...
http://ajplung.physiology.org/content/298/4/L593
Opal-Effect Branch Cartilage Ring - 18 Gauge - SpencersOpal-Effect Branch Cartilage Ring - 18 Gauge - Spencers
18 Gauge Opal Branch Cartilage Ring- Up your piercing game with the 18 Gauge Opal Branch Cartilage Ring, which features five beautiful opal gems.
http://www.spencersonline.com/product/accessories/body-jewelry/cartilage-tragus/18-gauge-opal-branch-cartilage-ring/pc/2021/c/2025/sc/2045/117136.uts?thumbnailIndex=21
Opal-Effect Branch Cartilage Ring - 18 Gauge - SpencersOpal-Effect Branch Cartilage Ring - 18 Gauge - Spencers
18 Gauge Opal Branch Cartilage Ring- Up your piercing game with the 18 Gauge Opal Branch Cartilage Ring, which features five beautiful opal gems.
http://www.spencersonline.com/product/accessories/body-jewelry/cartilage-tragus/18-gauge-opal-branch-cartilage-ring/pc/2021/c/2025/sc/2045/117136.uts?thumbnailIndex=22
7-Color Set Annealed Bendable Titanium Anodized Steel Nose Septum Cartilage Ring Hoops Rings Women sdwnet.com7-Color Set Annealed Bendable Titanium Anodized Steel Nose Septum Cartilage Ring Hoops Rings Women sdwnet.com
7-Color Set Annealed(Bendable) Titanium Anodized Steel Nose Septum Cartilage Ring Hoops (20G 3/8): Clothing,Loving, Shopping, Sharing,Guaranteed 100% Authentic,We provide a buyer protection guarantee.
http://sdwnet.com/Women/uqibxi-132698/Septum-Cartilage-Ring-Hoops-Color-Set.action
CZ and Flowers Cartilage Ring Rose Gold - Belly BlingCZ and Flowers Cartilage Ring Rose Gold - Belly Bling
CZ and Clay Flowers Curve to make this delicate piece your soon to be favorite. 316L Surgical Steel Ear Cartilage Barbell Stud. 16 GA. 1/4 barbell. Rose Gold Cartilage rings are always popular!
https://www.bellybling.net/collections/cartilage/products/cz-and-flowers-cartilage-ring-rose-gold
How Digestible is Beef Trachea - Puppy LeaderHow Digestible is Beef Trachea - Puppy Leader
Chewing is essential for your dog. If you are looking for a natural, delicious, and chewy treat to keep your pooch happy and healthy, you may consider buying them a beef trachea. But what is a beef trachea, and is it right for your dog?. The beef trachea is a long-lasting premium dog chew that is low in fat and rich in protein. Your dogs will tear it like candy, and they cant get enough. They are highly digestible and good for your dogs teeth and gum health.. Are you wondering why you should get a beef trachea for your pup? You are in the right place. In this article, you will find in-depth information about beef trachea. Open your eyes to absorb information. ...
https://puppyleader.com/how-digestible-is-beef-trachea/
NIOSHTIC-2 Publications Search - 20044485 - Particle deposition in a cast of human tracheobronchial airways.NIOSHTIC-2 Publications Search - 20044485 - Particle deposition in a cast of human tracheobronchial airways.
A meta description is an HTML tag in the HTML code of your website, which allows you to customize a section of text that describes the page itself. It plays a role in how your page is seen by search engine crawlers, and how it appears in SERPs
https://www.cdc.gov/niosh/nioshtic-2/20044485.html
q1 can you name these parts present in human respiratory system i that has cartilaginous rings ii that encloses the vocal cards...q1 can you name these parts present in human respiratory system i that has cartilaginous rings ii that encloses the vocal cards...
q1 can you name these parts present in human respiratory system i that has cartilaginous rings ii that encloses the vocal cards iii sheet of muscle th - Biology - TopperLearning.com | vkr4x33
https://www.topperlearning.com/answer/q1-can-you-name-these-parts-present-in-human-respiratory-system-i-that-has-cartilaginous-rings-ii-that-encloses-the-vocal-cards-iii-sheet-of-muscle-th/vkr4x33
12 Beef Trachea - Shore Thing Pet Supply12 Beef Trachea - Shore Thing Pet Supply
Trachea are a durable, crunchy chew that dogs love due to the higher fat content (compared to a bully stick). Trachea are known to be a natural source of glucosamine, which may help preserve joint health and mobility. The trachea can also be stuffed with anything from canned food to commercial raw food, and then frozen
https://shorethingpetsupply.com/products/12-trachea
Tracheal epithelium surface, SEM - Stock Image C036/9758 - Science Photo LibraryTracheal epithelium surface, SEM - Stock Image C036/9758 - Science Photo Library
Tracheal epithelium surface, scanning electron micrograph (SEM). The trachea or windpipe is secretory in nature, possessing many exocrine glands and being lined by a pseudostratified columnar epithelium in which ciliated and mucous cells predominate. The ciliated epithelial cells are interspersed with goblet mucosal cells which are covered by microvilli. Goblet cells produce mucous which is secreted through the microvilli and tiny particles present in inhaled air are trapped. The ciliated cells move the mucous upwards and out of the respiratory tract, thus cleaning the pathway. Magnification: x600 when shortest axis printed at 25 millimetres. - Stock Image C036/9758
http://www.sciencephoto.com/media/873621/view
Barkworthies Beef Trachea - Ruff House FL
Barkworthies Beef Tracheas offer a 100% digestible, sturdy all-natural dog chew with fat trimmings left on to make Barkworthies Beef Trachea both enticing and delicious! Barkworthies Beef Trachea also serve as a great dental chew by removing food residue and plaque. Barkworthies Beef Trachea are longer lasting for your
https://ruffhousefl.com/products/barkworthies-beef-trachea
NIOSHTIC-2 Publications Search - 20022832 - Interleukin-1 -induced airway hyperresponsiveness enhances substance P in...NIOSHTIC-2 Publications Search - 20022832 - Interleukin-1 -induced airway hyperresponsiveness enhances substance P in...
Interleukin (IL)-1 causes airway inflammation, enhances airway smooth muscle responsiveness, and alters neurotransmitter expression in sensory, sympathetic, and myenteric neurons. This study examines the role of intrinsic airway neurons in airway hyperresponsiveness (AHR) induced by IL-1. Ferrets were instilled intratracheally with IL-1 (0.3 g/0.3 ml) or saline (0.3 ml) once daily for 5 days. Tra
https://www.cdc.gov/niosh/nioshtic-2/20022832.html
K9 Chicken Gourmet Trachea - Pro-PetK9 Chicken Gourmet Trachea - Pro-Pet
An enticing and delicious 100% digestable beef trachea filled with a gourmet chicken treat filling for a blast of a culinary experience. K9 Chicken Gourmet Trachea comes in two conveniently sized packs:. Single Pack - One single K9 Chicken Gourmet Trachea. Bulk Pack - A package of ten K9 Chicken Gourmet Trachea. ...
https://www.pro-pet.co.za/product/dog-treats-k9-chicken-gourmet-trachea/
Dehydrated Lamb Trachea - 80gm - Rawganic Dog Food
Lamb Trachea are the smaller diameter version of beef trachea, but are also suitable for sensitive dogs that suffer from allergies and food intolerances. Lamb Trachea chews are hollow and come from the windpipe of a lamb. They are high in both chondroitin and glucosamine. These naturally occurring agents have both been proven as effective in promoting healthy joints in dogs ...
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Plus itPlus it
To study the mechanism of ether lipid accumulation which is characteristic of many tumors, we have compared the metabolism of lipids in primary rat tracheal epithelial cells and in a cell line derived from a benzo(a)pyrene-induced tumor. Growth of the primary epithelial cells in vitro resulted in the accumulation of alkyldiacylglycerols at levels (10% of total lipid) comparable to those found in the tumor cell line (B2-1). This class of ether lipids could not be detected in normal rat tracheal epithelium in vivo. A double isotope labeling method using [3H]- and [14C]palmitic acid was used to study metabolic stability of lipid classes in the cell cultures. Primary cells and B2-1 cells labeled with palmitic acid showed the greatest loss of label from triacylglycerols and free fatty acids during incubation in unlabeled media. A slight loss of label from the ester linkages of the alkyldiacylglycerols was observed in the primary epithelial cells but not the B2-1 cells. No label was lost from the ...
http://cancerres.aacrjournals.org/content/39/1/207
Plus itPlus it
We have previously shown that acetylcholine (ACh) induces oscillations in Ca++ and Ca++-activated Cl- currents (Clca) in tracheal myocytes. These oscillations are initiated by Ca++ release from inositol 1,4,5-trisphosphate-sensitive Ca++ stores and maintained by Ca++ influx, in part, through voltage-operated Ca++ channels. In the current study whole-cell Clca was measured in isolated tracheal smooth muscle cells as an index of changes in intracellular Ca++ concentration. We demonstrate that ACh-sensitive Ca++ stores and caffeine-sensitive Ca++ stores and caffeine-sensitive Ca++ stores are functionally linked but are refilled through distinct pathways. Two pathways responsible for replenishing ACh-sensitive Ca++ stores were identified. Ca++ influx through verapamil-sensitive voltage-operated Ca++ channels and Ca++ uptake through cyclopiazonic acid-sensitive Ca++ pumps accounted for 80% of the response. The other 20% of the response was both cyclopiazonic acid- and verapamil-insensitive. In ...
http://jpet.aspetjournals.org/content/277/2/789
Histopathology of Inhalation of Industrial Bleach and Detergent Mixture on Epithelial Layer of Trachea in Mice
This study is the effects of inhalation toxic mixture of bleach and detergent was examined on the epithelial layer of trachea in the mice. In this study, 42 adult male mice NMRI race weighing 35-40 gr and from age 8 to 10 weeks were divided into 6 experimental groups and one control group. Experimental groups 1-2-3 with the using of chamber, as inhalation 20 minutes were exposure to spray the amount 1 cc of mixture of bleach and detergent by nebulizer. Experimental groups 4-5-6 were for 35 minutes to inhale the same amount of material. Mice killed at 24-48-72 hours after inhalation and the trachea was studied pathology. In microscopic sections of tissue taken from the trachea the experimental group compared with the control group was changed to include: stimulation and activation of the respiratory epithelium hungarian (Mocusa layer), reducing the length of ciliated columnar cells, reducing the number of goblet cells ,loss of cilia, chaos and clutter on the order of tissue. In addition, statistically,
http://jchr.sinaweb.net/article_531848.html
Xenbase Anatomy Ontology: Attributions for mucociliary epithelium [Xenopus]Xenbase Anatomy Ontology: Attributions for mucociliary epithelium [Xenopus]
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari. ...
http://www.xenbase.org/anatomy/attribution.do?objId=3433&objName=ANATOMY_ITEM&objNameSrt=ANAT&objColName=DESCRIPTION&attPage=PAPER&action=VIEW&litOnly=0&att=mucociliary+epithelium&pageType=ANAT&tabId=3
Lung Trachea & Bronchial Tree Diagram & Function | Body MapsLung Trachea & Bronchial Tree Diagram & Function | Body Maps
Trachea The trachea, also called the windpipe, is part of the passageway that supplies air to the lungs. Any prolonged blockage, even for a few minutes, can cause death. The trachea is about 4.
https://www.healthline.com/human-body-maps/lung-trachea-bronchial-tree/male
Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action - Nottingham ePrintsDiscovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action - Nottingham ePrints
A series of dibasic des-hydroxy β2 receptor agonists has been prepared and evaluated for potential as inhaled ultra-long acting bronchodilators. Determination of activities at the human β-adrenoreceptors demonstrated a series of highly potent and selective β2 receptor agonists that were progressed to further study in a guinea pig histamine-induced bronchoconstriction model. Following further assessment by; onset studies in guinea pig tracheal rings and human bronchial rings contracted with methacholine (guinea pigs) or carbachol (humans), duration of action studies in guinea pigs after intratracheal (i. t.) administration and further selectivity and safety profiling AZD3199 was shown to have an excellent over all profile and was progressed into clinical evaluation as a new ultra-long acting inhaled β2 receptor agonist with rapid onset of action.. ...
http://eprints.nottingham.ac.uk/2950/
Cartilage rings of the trachea | definition of Cartilage rings of the trachea by Medical dictionaryCartilage rings of the trachea | definition of Cartilage rings of the trachea by Medical dictionary
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https://medical-dictionary.thefreedictionary.com/Cartilage+rings+of+the+trachea
Effects of intravenous anesthetics on Ca<sup>2+</sup> sensitivity in canine tracheal smooth...
TY - JOUR. T1 - Effects of intravenous anesthetics on Ca2+ sensitivity in canine tracheal smooth muscle. AU - Hanazaki, Motohiko. AU - Jones, Keith A.. AU - Warner, David O.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 2000/1. Y1 - 2000/1. N2 - Background: Halothane and other volatile anesthetics relax airway smooth muscle in part by decreasing the amount of force produced for a particular intracellular calcium concentration (the Ca2+ sensitivity) during muscarinic receptor stimulation. In this study, ketamine, propofol, and midazolam were evaluated to determine whether the inhibitory effect of volatile anesthetics on this signal transduction pathway is a general property of other types of anesthetic drugs. Methods: A β-escin permeabilized canine tracheal smooth muscle preparation was used. Ketamine, propofol, and midazolam, in concentrations producing near-maximal relaxation in intact airway smooth muscle (200 μM, 270 μM, and 100 μM, respectively), were applied ...
https://mayoclinic.pure.elsevier.com/en/publications/effects-of-intravenous-anesthetics-on-casup2sup-sensitivity-in-ca
Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.<...
TY - JOUR. T1 - Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.. AU - Pennings, H.J.. AU - Kramer, K.. AU - Bast, A.. AU - Buurman, W.A.. AU - Wouters, E.F.M.. PY - 1998. Y1 - 1998. N2 - Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10. AB - Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10. U2 - 10.1183/09031936.98.12010045. DO - ...
https://research.vu.nl/en/publications/tumour-necrosis-factor-a-induces-hyperreactivity-in-tracheal-smoo
Different phosphorylated forms of myosin in contracting tracheal smooth muscle<...
TY - JOUR. T1 - Different phosphorylated forms of myosin in contracting tracheal smooth muscle. AU - Persechini, A.. AU - Kamm, K. E.. AU - Stull, J. T.. PY - 1986. Y1 - 1986. N2 - Calmodulin-dependent myosin light chain kinase phosphorylates two light chain subunits on each myosin molecule. We have developed a method for measuring nonphosphorylated, monophosphorylated, and diphosphorylated forms of myosin in smooth muscle. Four protein bands were separated in tissue extracts by nondenaturing polyacrylamide gel electrophoresis in the presence of pyrophosphate. Immunoblots demonstrated that three forms (designated M, MP, and MP2) reacted with rabbit antisera prepared against the purified phosphorylated light chain (P-light chain) from bovine tracheal smooth muscle. Evidence was obtained that M, MP, and MP2 represented nonphosphorylated, monophosphorylated, and diphosphorylated myosin, respectively, and that the other protein band was probably filamin. The formation of different phosphorylated ...
https://utsouthwestern.pure.elsevier.com/en/publications/different-phosphorylated-forms-of-myosin-in-contracting-tracheal-
Hyaline Cartilage From The Human Trachea He Stain Lm X26 Stock Photo | Getty ImagesHyaline Cartilage From The Human Trachea He Stain Lm X26 Stock Photo | Getty Images
View Stock Photo of Hyaline Cartilage From The Human Trachea He Stain Lm X26. Find premium, high-resolution photos at Getty Images.
https://www.gettyimages.ae/detail/photo/hyaline-cartilage-from-the-human-trachea-h-high-res-stock-photography/vis98764
Contractures produced by carbamate anticholinesterases in bovine tracheal smooth muscle. - PubMed - NCBIContractures produced by carbamate anticholinesterases in bovine tracheal smooth muscle. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/7166004?dopt=Abstract
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AID 211521 - Compound was evaluated for antagonistic activity towards Tachykinin receptor 2 at guinea pig trachea - PubChemAID 211521 - Compound was evaluated for antagonistic activity towards Tachykinin receptor 2 at guinea pig trachea - PubChem
BioAssay record AID 211521 submitted by ChEMBL: Compound was evaluated for antagonistic activity towards Tachykinin receptor 2 at guinea pig trachea.
https://pubchem.ncbi.nlm.nih.gov/bioassay/211521
THE UPTAKE KINETICS AND METABOLISM OF EXTRANEURONAL NORADRENALINE IN GUINEA‐PIG TRACHEA AS STUDIED WITH QUANTITATIVE...
ODONNELL S.R. and SAAR N. (1978) THE UPTAKE KINETICS AND METABOLISM OF EXTRANEURONAL NORADRENALINE IN GUINEA‐PIG TRACHEA AS STUDIED WITH QUANTITATIVE FLUORESCENCE MICROPHOTOMETRY. British Journal of Pharmacology, 62 2: 235-239. doi:10.1111/j.1476-5381.1978.tb08451.x ...
https://espace.library.uq.edu.au/view/UQ:403769
Carina tracheae | definition of carina tracheae by Medical dictionaryCarina tracheae | definition of carina tracheae by Medical dictionary
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China Human Larynx Trachea Bronchi Model - China Larynx Trachea Bronchi Model, Anatomical Larynx Trachea Bronchi ModelChina Human Larynx Trachea Bronchi Model - China Larynx Trachea Bronchi Model, Anatomical Larynx Trachea Bronchi Model
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JCI - Leukotriene receptors as potential therapeutic targetsJCI - Leukotriene receptors as potential therapeutic targets
CysLTs are inflammatory lipid mediators implicated in multiple diseases, including asthma, allergic rhinitis, cardiovascular disease, atopic dermatitis, and experimental autoimmune encephalitis (a model of multiple sclerosis). The identification of CysLT receptors, generation of CysLT receptor-deficient mice, and development of specific antagonists have expanded the scope of functions of these mediators in disease. In particular, signaling via these receptors is implicated in many components of these diseases, such as bronchoconstriction, increased microvascular permeability, recruitment of effector cells, mucus and cytokine secretion, and fibrosis (127-133). In this section, we discuss the functional relevance of CysLT receptors to various diseases as determined by animal experiments.. Bronchoconstriction. LTC4 and LTD4 are equipotent in guinea pig tracheal smooth muscle, while LTD4 is more effective in peripheral airways (134). For example, the potency of LTD4 in the guinea pig lung ...
https://chinatirui.net.mobile.jci.org/articles/view/97946
JCI - Leukotriene receptors as potential therapeutic targetsJCI - Leukotriene receptors as potential therapeutic targets
CysLTs are inflammatory lipid mediators implicated in multiple diseases, including asthma, allergic rhinitis, cardiovascular disease, atopic dermatitis, and experimental autoimmune encephalitis (a model of multiple sclerosis). The identification of CysLT receptors, generation of CysLT receptor-deficient mice, and development of specific antagonists have expanded the scope of functions of these mediators in disease. In particular, signaling via these receptors is implicated in many components of these diseases, such as bronchoconstriction, increased microvascular permeability, recruitment of effector cells, mucus and cytokine secretion, and fibrosis (127-133). In this section, we discuss the functional relevance of CysLT receptors to various diseases as determined by animal experiments.. Bronchoconstriction. LTC4 and LTD4 are equipotent in guinea pig tracheal smooth muscle, while LTD4 is more effective in peripheral airways (134). For example, the potency of LTD4 in the guinea pig lung ...
https://j8k9.com.www.mobile.jci.org/articles/view/97946
PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells - Semantic...PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells - Semantic...
BACKGROUND Airway smooth muscle contributes to the pathogenesis of pulmonary diseases by secreting inflammatory mediators such as interleukin-8 (IL-8). IL-8 production is in part regulated via activation of Gq-and Gs-coupled receptors. Here we study the role of the cyclic AMP (cAMP) effectors protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac1 and Epac2) in the bradykinin-induced IL-8 release from a human airway smooth muscle cell line and the underlying molecular mechanisms of this response. METHODS IL-8 release was assessed via ELISA under basal condition and after stimulation with bradykinin alone or in combination with fenoterol, the Epac activators 8-pCPT-2-O-Me-cAMP and Sp-8-pCPT-2-O-Me-cAMPS, the PKA activator 6-Bnz-cAMP and the cGMP analog 8-pCPT-2-O-Me-cGMP. Where indicated, cells were pre-incubated with the pharmacological inhibitors Clostridium difficile toxin B-1470 (GTPases), U0126 (extracellular signal-regulated kinases ERK1/2) and Rp-8-CPT-cAMPS (PKA). The
https://www.semanticscholar.org/paper/PKA-and-Epac-cooperate-to-augment-bradykinin-induc-Roscioni-Kistemaker/45af31b28236123860d662d7057a477d02dcbc79
Anion selectivity of the chloride-transport process in dog tracheal epithelium.<...
TY - JOUR. T1 - Anion selectivity of the chloride-transport process in dog tracheal epithelium.. AU - Widdicombe, J. H.. AU - Welsh, M. J.. PY - 1980/9. Y1 - 1980/9. N2 - We have measured the fluxes of 82Br or 131I across short-circuited dog tracheal epithelium following complete replacement of chloride in the bathing medium by either bromide or iodide. In addition, we have partly replaced the bathing chloride with bromide, iodide, or thiocyanate and studied the effects of these anions on 36Cl fluxes. Our results show that the affinity sequence for the chloride transport process is I , Br congruent to Cl, that Br is transported, but that I is not. Thiocyanate is a potent inhibitor of chloride transport, and its effects are greater than those predicted by a simple competitive interaction with chloride for transport sites.. AB - We have measured the fluxes of 82Br or 131I across short-circuited dog tracheal epithelium following complete replacement of chloride in the bathing medium by either ...
https://ucdavis.pure.elsevier.com/en/publications/anion-selectivity-of-the-chloride-transport-process-in-dog-trache
Lung Injury; Relates to Real-Time Endoscopic Monitoring of Single Cells Respiratory Health in Lung
The goal of this proposal is to design a portable bronchoscope that can determine the health status of the tracheal epithelial lining cells by analyzing changes in their metabolic profile. The device is intended to be used to quickly single out which individuals is showing injury and inflammation in the trachea and lung and therefore to provide them with the most adequate and early care. In this closing year 1 funding period, we have built the bronchoscope and done some preliminary testing on mouse trachea samples exposed to chemicals known to injure the tracheal epithelium. The size of the bronchoscope is quite small and will allow its transport and use by the military in the field or remote locations, while the small size of the instrument could permit its use on awake patients. Following evaluation of the field of research we have decided to develop a hybrid system Camera and Raster with two modalities seek and focus. The former modality will allow low magnification scan of the trachea and lung
https://apps.dtic.mil/sti/citations/AD1048375
Tube continued: Morphogenesis of the Drosophila tracheal system<...Tube continued: Morphogenesis of the Drosophila tracheal system<...
TY - JOUR. T1 - Tube continued. T2 - Morphogenesis of the Drosophila tracheal system. AU - Schottenfeld, Jodi. AU - Song, Yanjun. AU - Ghabrial, Amin S.. N1 - Funding Information: The authors apologize to those whose work we were unable to include within the limited confines of this review. We thank Dena Alpert for her insightful comments on the manuscript. JS has received support from NIH Developmental Biology training grant (T32-HD007516-12) and is currently supported by an NIH NRSA postdoctoral fellowship (F32-GM090438). ASG gratefully acknowledges research support from the NIH (1R01GM089782-01A1), the March of Dimes (Basil OConnor award), a McCabe Scholar award, an ACS pilot grant, and the University of Pennsylvania. PY - 2010/10. Y1 - 2010/10. N2 - The Drosophila respiratory organ (tracheal system) consists of epithelial tubes, the morphogenesis of which is controlled by distinct sets of signaling pathways and transcription factors. The downstream events controlling tube formation and ...
https://collaborate.princeton.edu/en/publications/tube-continued-morphogenesis-of-the-drosophila-tracheal-system
Differentiated structure and function of cultures from human tracheal epithelium<...
TY - JOUR. T1 - Differentiated structure and function of cultures from human tracheal epithelium. AU - Yamaya, M.. AU - Finkbeiner, W. E.. AU - Chun, S. Y.. AU - Widdicombe, Jonathan. PY - 1992. Y1 - 1992. N2 - Here we describe the conditions which allow cultured human tracheal epithelial cells to retain the ion transport properties and ultrastructure of the original tissue. The order of potency of growth supports and media additives in elevating baseline short-circuit current (I(sc)) and responses to mediators were vitrogen gel (VIT) , extracellular matrix from bovine corneal endothelial cells (ECM) , human placental collagen (HPC), and 2% Ultroser G serum substitute (USG) , 5% fetal calf serum (FCS) , defined growth factors (GF). For all combinations of medium and growth supports, an air interface (AIR) gave better electrical properties than immersion feeding (IMM). As opposed to our earlier conditions (HPC/FCS/IMM), the best new combination (VIT/USG/AIR) produced higher baseline I(sc) (58.0 ...
https://ucdavis.pure.elsevier.com/en/publications/differentiated-structure-and-function-of-cultures-from-human-trac
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate...Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate...
Kesimer M., Scull M., Brighton B., DeMaria G., Burns K., ONeal W., Pickles R.J., Sheehan J.K.. Airway mucus forms the structural basis of the local innate immune defense mechanism. It is an integrated, active, viscoelastic gel matrix evolved to protect the exposed lung from physical, chemical, and pathological erosion. Exosomes are biologically active vesicles secreted by different cell types including epithelial, hematopoietic, and some tumor cells. They are also present in some biological fluids such as serum, urine, breast milk, and bronchoalveolar lavage fluid. In this study, we demonstrate for the first time that exosome-like vesicles with antiviral properties are present in human tracheobronchial epithelial (HTBE) cell culture secretions. These vesicles have been isolated by differential centrifugation and are characterized further by mass spectrometry, flow cytometry, immunoblotting, electron microscopy, and light-scattering methods. HTBE vesicles exhibited characteristic exosomal size ...
http://www.uniprot.org/citations/19190083
Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroidsExpression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids
Interleukin (IL)-8 is a C-X-C chemokine that potently chemoattracts and activates neutrophils. We determined whether IL-8 could be produced by human airway smooth muscle cells in culture and examined its regulation. TNF-alpha stimulated IL-8 mRNA expression and protein release in a time- and dose-de …
https://pubmed.ncbi.nlm.nih.gov/9448049/?dopt=Abstract
Antiinflammatorische Zytokine in der Pathogenese des Asthma bronchialeAntiinflammatorische Zytokine in der Pathogenese des Asthma bronchiale
The results of this present thesis show a deficiency of IL-10 production in alveolar macrophages in asthma. The reduced IL-10 expression on protein and m-RNA level correlated with an increased production of pro-inflammatory cytokines such as TNF-(, MIP1- ( and GM-CSF. These observations implicate an impaired IL-10 synthesis in asthma with a subsequent prolongation of the inflammatory response. This leads to the conclusion that a dysbalance between pro- and anti-inflammatory cytokines is present in asthma and may be therefore of pathogenetic importance. The reduced sensitivity of alveolar macrophages to the inhibitory effects of exogenous IL-10 compared to peripheral blood monocytes may be caused by different signal transduction mechanisms. The expression of the proinflammatory cytokines RANTES and IL-8 in cultured human airway smooth muscle cells led to the conclusion that airway smooth muscle cells may act beside their contractile function as immunomodulatory cells in the pathogenesis of ...
https://edoc.hu-berlin.de/handle/18452/14460?C=N
Antiinflammatorische Zytokine in der Pathogenese des Asthma bronchialeAntiinflammatorische Zytokine in der Pathogenese des Asthma bronchiale
The results of this present thesis show a deficiency of IL-10 production in alveolar macrophages in asthma. The reduced IL-10 expression on protein and m-RNA level correlated with an increased production of pro-inflammatory cytokines such as TNF-(, MIP1- ( and GM-CSF. These observations implicate an impaired IL-10 synthesis in asthma with a subsequent prolongation of the inflammatory response. This leads to the conclusion that a dysbalance between pro- and anti-inflammatory cytokines is present in asthma and may be therefore of pathogenetic importance. The reduced sensitivity of alveolar macrophages to the inhibitory effects of exogenous IL-10 compared to peripheral blood monocytes may be caused by different signal transduction mechanisms. The expression of the proinflammatory cytokines RANTES and IL-8 in cultured human airway smooth muscle cells led to the conclusion that airway smooth muscle cells may act beside their contractile function as immunomodulatory cells in the pathogenesis of ...
https://edoc.hu-berlin.de/handle/18452/14460
Biochemical characterization of native usher protein complexes from a vesicular subfraction of tracheal epithelial cells<...
TY - JOUR. T1 - Biochemical characterization of native usher protein complexes from a vesicular subfraction of tracheal epithelial cells. AU - Zallocchi, Marisa L. AU - Sisson, Joseph Harold. AU - Cosgrove, Dominic E. PY - 2010/2/16. Y1 - 2010/2/16. N2 - Usher syndrome is the major cause of deaf/blindness in the world. It is a genetic heterogeneous disorder, with nine genes already identified as causative for the disease. We noted expression of all known Usher proteins in bovine tracheal epithelial cells and exploited this system for large-scale biochemical analysis of Usher protein complexes. The dissected epithelia were homogenized in nondetergent buffer and sedimented on sucrose gradients. At least two complexes were evident after the first gradient: one formed by specific isoforms of CDH23, PCDH15, and VLGR-1 and a different one at the top of the gradient that included all of the Usher proteins and rab5, a transport vesicle marker. TEM analysis of these top fractions found them enriched in ...
https://nebraska.pure.elsevier.com/en/publications/biochemical-characterization-of-native-usher-protein-complexes-fr
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Immunohistochemical characterization of the rabbit tracheal cartilagesImmunohistochemical characterization of the rabbit tracheal cartilages
The objective of this study was to immunohistochemically elucidate the major extracellular matrix constituents of rabbit tracheal cartilage. The impetus for this project is the need for crucial design and validation criteria for tissue engineering juxtaposed with the conspicuous lack of trachea extracellular matrix data in the literature. Tracheal tissue specimens were harvested from New Zealand White rabbits, and were immunostained for collagen I, collagen II, aggrecan and decorin; and a Verhoeff-Van Gieson stain was performed to visualize elastin. The most striking result was the highly organized relationship between distinct fibrous (containing collagen I, decorin and elastin) and hyaline-like (containing collagen II and aggrecan) regions of the tracheal wall. The tracheal cartilage stained strongly with collagen II throughout, with periodic bands of aggrecan in the tracheal arches, meaning that there were areas void of aggrecan immunostaining alternating with areas with strong aggrecan
https://www.scirp.org/journal/paperinformation.aspx?paperid=2895
IgE induces proliferation in human airway smooth muscle cells: role of MAPK and STAT3 pathways | Allergy, Asthma & Clinical...IgE induces proliferation in human airway smooth muscle cells: role of MAPK and STAT3 pathways | Allergy, Asthma & Clinical...
Airway remodeling is not specifically targeted by current asthma medications, partly owing to the lack of understanding of remodeling mechanisms, altogether posing great challenges in asthma treatment. Increased airway smooth muscle (ASM) mass due to hyperplasia/hypertrophy contributes significantly to overall airway remodeling and correlates with decline in lung function. Recent evidence suggests that IgE sensitization can enhance the survival and mediator release in inflammatory cells. Human ASM (HASM) cells express both low affinity (FcεRII/CD23) and high affinity IgE Fc receptors (FcεRI), and IgE can modulate the contractile and synthetic function of HASM cells. IgE was recently shown to induce HASM cell proliferation but the detailed mechanisms remain unknown. We report here that IgE sensitization induces HASM cell proliferation, as measured by 3H-thymidine, EdU incorporation, and manual cell counting. As an upstream signature component of FcεRI signaling, inhibition of spleen tyrosine kinase
https://aacijournal.biomedcentral.com/articles/10.1186/1710-1492-9-41
In vitro and in vivo lung deposition of coated magnetic aerosol particles<...
TY - JOUR. T1 - In vitro and in vivo lung deposition of coated magnetic aerosol particles. AU - Xie, Yuanyuan. AU - Longest, P. Worth. AU - Xu, Yun Hao. AU - Wang, Jian Ping. AU - Wiedmann, Timothy Scott. PY - 2010/11. Y1 - 2010/11. N2 - The magnetic induced deposition of polydispersed aerosols composed of agglomerated superparamagnetic particles was measured with an in vitro model system and in the mouse trachea and deep lung for the purpose of investigating the potential of site specific respiratory drug delivery. Oleic acid coated superparamagnetic particles were prepared and characterized by TEM, induced magnetic moment, and iron content. The particles were dispersed in cyclohexane, aerosolized with an ultrasonic atomizer and dried by sequential reflux and charcoal columns. The fraction of iron deposited on glass tubes increased with particle size and decreasing flow rate. High deposition occurred with a small diameter tube, but the deposition fraction was largely independent of tube size at ...
https://minnesota-staging.pure.elsevier.com/en/publications/in-vitro-and-in-vivo-lung-deposition-of-coated-magnetic-aerosol-p
Evaluation of nocturnal bronchoconstriction by all night tracheal sound monitoring. | ThoraxEvaluation of nocturnal bronchoconstriction by all night tracheal sound monitoring. | Thorax
BACKGROUND: A study was undertaken to evaluate the reliability of a digital tracheal sound analyser (ELENS-DSA) in predicting nocturnal changes in airways resistance in asthmatic patients. This device allows continuous measurement of the proportion of the time occupied by wheezing (Wh%). METHODS: Nocturnal polygraphic studies with simultaneous continuous monitoring of tracheal sounds and airways resistance were performed in seven patients with nocturnal asthma. In order to evaluate the possible bias in wheezing estimation, each tracheal sound recording was passed through the automatic analyser and simultaneously monitored with earphones by an experienced observer. RESULTS: The device detected audible wheezing with an optimal sensitivity and specificity of 70%. Snoring was a minor cause of the relatively poor characteristics of the system. A close correlation (p , 0.001) between Wh% and airways resistance was observed only in those patients with the highest increase in resistance; when the ...
http://thorax.bmj.com/content/51/7/694
PawHealer Trachea Soother Syrup 2PAK Hound Honey - Natural Herbal Remedy for Symptoms of Collapsed Trachea - Tastes Good - Easy...PawHealer Trachea Soother Syrup 2PAK Hound Honey - Natural Herbal Remedy for Symptoms of Collapsed Trachea - Tastes Good - Easy...
Free Shipping Included! PawHealer Trachea Soother Syrup 2PAK Hound Honey - Natural Herbal Remedy for Symptoms of Collapsed Trachea - Tastes Good - Easy to Administer (5 fl oz/ea) ... by PawHealer at Online Medicine Tips. MPN: PR-COM-RT-X1084344. Hurry! Limited time offer. Offer valid only while supplies last. Herbal Supplement - liquid - 5 fl oz for symptoms of: Collapsed Trachea, Honking Cough - Wheezing - Signs of Heat like thirsty and /or panting - Rapid Breathing - Gagging Cough - Hacking CoughSymptoms
https://www.onlinemedicinetips.com/omtp/6107/pawhealer-trachea-soother-syrup-2pak-hound-honey-natural-herbal-remedy-for-symptoms-of-collapsed-trachea-tastes-good-easy-to-administer-5-fl-oz-ea
abscess of trachea是什么意思 abscess of trachea的用法 海词词典abscess of trachea是什么意思 abscess of trachea的用法 海词词典
海词词典，最权威的学习词典，专业出版abscess of trachea是什么意思，abscess of trachea的用法，abscess of trachea翻译和读音等详细讲解。海词词典：学习变容易，记忆很深刻。
http://m.dict.cn/abscess%20of%20trachea%0D
Postintubation Stenosis of the Trachea - Case Reviews | proLékaře.czPostintubation Stenosis of the Trachea - Case Reviews | proLékaře.cz
Stenoses of the respiratory tract are life threatening conditions of various origins. The authors give referrence on 21 patients operated for postintubation stenoses of their trachea at the IInd Surgical Clinic of the UPJŠ Medical Faculty, the Faculty Hospital of L. Pasteur in Košice, from 01. 01. 1999 to 30. 06. 2005. All patients had a tracheobronchoscopic examination and a CT examination completed prior to the procedure. Within 24 hours of their admission, 9 patients were operated, 7 underwent resection procedures and 2 patients had Montgomerys T-cannula introduced. 12 patients had their procedures planned, and were operated later than 24 hours after their admission. 10 patients underwent resections of the trachea, 2 had Montgomerys Tcannula implanted. The postoperative course following the resection of the trachea was without complications in 14 patients, 1 patient experienced transitional oedema in the anastomosis and 2 patients suffered restenoses. In this patient group, no fatal case ...
https://www.prolekare.cz/en/journals/perspectives-in-surgery/2006-6/postintubation-stenosis-of-the-trachea-case-reviews-4296
Mouse and Rabbit Trachea
Hi Histonetters, We are working with mouse and rabbit trachea and are experiencing problems with the histology. We are seeing fragmentation, lifting off and ultimate destruction of the epithelial and underlying layers. This does not happen with all samples but is occuring far too often. We are fixing the mouse tissue in formalin 18-24 hrs at 4C and then transferring to 70% ETOH. The rabbit tissue is fixed in formalin at 4C for 24 hrs and then processed. We are using alcohols for dehydration and xylene for clearing. I see where other folks are using different dehydrants etc for mouse tissue but this is not an option for us at the moment. We have processed for very short durations and longer but still see quite a bit of variation. We are doing routine staining of the tissue as well as some immunohistochemistry. Do you have suggestions for fixatives and length and temperature of fixation? Suggestions for processing protocols, ie length, temp use of vacuum? Suggestions for ideal paraffin? Thanks, ...
http://www.histosearch.com/histonet/Apr00/MouseandRabbitTrachea.html
Brevet US4889112 - Apparatus for performing a tracheostomy operation - Google BrevetsBrevet US4889112 - Apparatus for performing a tracheostomy operation - Google Brevets
Apparatus and method for performing a tracheostomy operation wherein the trachea is penetrated using a syringe needle (23) attached to a syringe (20) to form a small opening in the trachea. A guide wire (30) is inserted into the trachea through the needle (23) and after the syringe (20) is removed from the needle. The needle (23) is then removed from the trachea leaving the guide wire (30) inserted in the trachea. An instrument (T) specifically adapted for use in tracheostomy operations is inserted into the small trachea opening produced by the needle (23) while being guided by the guide wire (30). The instrument (T) being opened after insertion into the trachea to widen the trachea opening and a cannula for insertion into the opening of the trachea after having been widened by the instrument (T).
http://www.google.fr/patents/US4889112
Experimental trial of balloon-expandable, metallic Palmaz stent in the trachea. - Semantic ScholarExperimental trial of balloon-expandable, metallic Palmaz stent in the trachea. - Semantic Scholar
OBJECTIVE To determine the effect of the Palmaz stent, which has been successfully used to relieve airway obstruction in a small group of children, on the normal and operated on animal trachea. DESIGN In this experimental trial, stents were placed bronchoscopically in the thoracic tracheae of 4 groups of 50 anesthetized cats. The cats in group 1 (adults, n = 10) and group 2 (kittens, n = 10) had normal tracheae; the cats in group 3 (adults, n = 15) underwent horizontal tracheal incision and closure; and the cats in group 4 (adults, n = 15) underwent pericardial patch tracheoplasty. In group 3 and 4, the stents were inserted in 10 cats and 5 cats served as controls. Stents were inflated to a 15-mm diameter in group 1 and an 8-mm diameter in the other groups. Half of the animals with stents were killed 5 weeks after the procedure, and the others, 10 weeks after the procedure. SETTING The Hospital for Sick Children, Toronto, Ontario. RESULTS In group 1, 1 animal died of tracheal perforation. A mild
https://www.semanticscholar.org/paper/Experimental-trial-of-balloon-expandable-metallic-Fraga-Filler/6145722867b20d5baeca4d84a8b75347a4e70eb5
ORBi: Browsing ORBiORBi: Browsing ORBi
in American Journal of Veterinary Research (2003), 64. OBJECTIVE: To determine the effect of histamine on the contractile elements of the respiratory tract in neonatal calves and young adult cattle. SAMPLE POPULATION: Samples of trachealis muscle, bronchi ... [more ▼]. OBJECTIVE: To determine the effect of histamine on the contractile elements of the respiratory tract in neonatal calves and young adult cattle. SAMPLE POPULATION: Samples of trachealis muscle, bronchi, and intrapulmonary arteries and veins dissected from the respiratory tracts of healthy bovids (2 to 8 days and 16 to 20 months old). PROCEDURE: Histamine cumulative concentration-effect curves (10(-6) to 10(-3) M) were constructed in duplicate smooth muscle samples mounted in organ baths. Contractile responses to histamine were compared with reference contractions elicited by methacholine (10(-5) M) for airways or KCl (127 mM) for vessels. RESULTS: In young adult cattle, trachealis muscle had a substantial contractile response to ...
http://orbi.ulg.ac.be/browse?type=author&sort_by=1&order=DESC&rpp=20&etal=3&value=Desmecht%2C+Daniel+p001506&offset=160
Trachea and Esophagus Conditions Wisconsin: Trachea and Esophagus Procedures and Specialists | Aurora Health CareTrachea and Esophagus Conditions Wisconsin: Trachea and Esophagus Procedures and Specialists | Aurora Health Care
Learn about trachea and esophagus conditions, and procedures for diagnosing and treating trachea and esophagus conditions from Aurora Health Care, serving Eastern Wisconsin and Northeastern Illinois
https://www.aurorahealthcare.org/services/otolaryngology/trachea-esophagus
The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slicesThe PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices
Combination therapy of PDE4 inhibitors and anticholinergics induces bronchoprotection in COPD. Mechanical forces that arise during bronchoconstriction may contribute to airway remodeling. Therefore, we investigated the impact of PDE4 inhibitors and anticholinergics on bronchoconstriction-induced remodeling. Because of the different mechanism of action of PDE4 inhibitors and anticholinergics, we hypothesized functional interactions of these two drug classes. Guinea pig precision-cut lung slices were preincubated with the PDE4 inhibitors CHF-6001 or roflumilast and/or the anticholinergics tiotropium or glycopyorrolate, followed by stimulation with methacholine (10 μM) or TGF-β1 (2 ng/ml) for 48 h. The inhibitory effects on airway smooth muscle remodeling, airway contraction, and TGF-β release were investigated. Methacholine-induced protein expression of smooth muscle-myosin was fully inhibited by CHF-6001 (0.3-100 nM), whereas roflumilast (1 µM) had smaller effects. Tiotropium and ...
https://www.aquilo.nl/index.php/pde4-inhibitor-chf-6001-lamas-inhibit-bronchoconstriction-induced-remodeling-lung-slices/
Chapter 37. Benign & Malignant Disorders of the Trachea | CURRENT Diagnosis & Treatment in Otolaryngology-Head & Neck Surgery,...Chapter 37. Benign & Malignant Disorders of the Trachea | CURRENT Diagnosis & Treatment in Otolaryngology-Head & Neck Surgery,...
The adult trachea measures approximately 12 cm but varies anywhere from 10 to 13 cm depending on height and sex. As there is some variability in the length, the anterior portion of the trachea is not subject to tremendous change, for the most part is composed of cartilage, and is C-shaped. The rings maybe complete or bifid. The posterior part of the trachea is also called the membranous portion and is the part of the airway that moves with breathing (Figure 37-1A). ...
http://accesssurgery.mhmedical.com/content.aspx?bookid=386§ionid=39944076
Image reuse, the new low of UCL trachea transplanter Martin Birchall? - For Better ScienceImage reuse, the new low of UCL trachea transplanter Martin Birchall? - For Better Science
With his three trachea transplant clinical trials suspended, the British laryngologist and UCL professor Martin Birchall now tries to pull at least the clinical trial RegenVox, which is about the regenerated voice-box (larynx) and upper trachea, out of the bog. In order to get an approval to transplant human patients, UCLs chief trachea transplanter tries to prove…
https://forbetterscience.com/2017/12/27/image-reuse-the-new-low-of-ucl-trachea-transplanter-martin-birchall/?like_comment=10103&_wpnonce=dbcf366308
The Trachea (Human Anatomy): Picture, Function, Conditions, and MoreThe Trachea (Human Anatomy): Picture, Function, Conditions, and More
WebMDs Trachea Anatomy Page provides a detailed image and definition of the trachea. Learn about its function, location, and conditions that affect the trachea.
https://www.webmd.com/lung/picture-of-the-trachea
Control of tracheal tubulogenesis by Wingless signaling | DevelopmentControl of tracheal tubulogenesis by Wingless signaling | Development
The tubular epithelium of the Drosophila tracheal system forms a network with a stereotyped pattern consisting of cells and branches with distinct identity. The tracheal primordium undergoes primary branching induced by the FGF homolog Branchless, differentiates cells with specialized functions such as fusion cells, which perform target recognition and adhesion during branch fusion, and extends branches toward specific targets. Specification of a unique identity for each primary branch is essential for directed migration, as a defect in either the EGFR or the Dpp pathway leads to a loss of branch identity and the misguidance of tracheal cell migration. Here, we investigate the role of Wingless signaling in the specification of cell and branch identity in the tracheal system. Wingless and its intracellular signal transducer, Armadillo, have multiple functions, including specifying the dorsal trunk through activation of Spalt expression and inducing differentiation of fusion cells in all fusion ...
https://dev.biologists.org/content/127/20/4433?ijkey=d45ddf262bd479147874c369a65cae671933fb96&keytype2=tf_ipsecsha
Control of cell migration and branch morphogenesis during Drosophila tracheal development. :: MPG.PuReControl of cell migration and branch morphogenesis during Drosophila tracheal development. :: MPG.PuRe
Author: Chen, C. K.; Genre: Thesis; Title: Control of cell migration and branch morphogenesis during Drosophila tracheal development.
https://pure.mpg.de/pubman/faces/ViewItemFullPage.jsp?itemId=item_600478
Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea | eLifeTwo-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea | eLife
The Drosophila tracheal fate is stabilized by the combination of transcriptional programs to control tissue architecture and tissue-level input sensitive to tubular geometry, ensuring the robust mechanism of organ determination.
https://elifesciences.org/articles/45145
Plus itPlus it
WFDC2/HE4 encodes a poorly characterised secretory protein that shares structural similarity to the multifunctional host defence protein, SLPI, through possession of two conserved Whey Acidic Protein/four disulphide-core (WFDC) domains. Like SLPI, WFDC2 is expressed in multiple epithelia within the respiratory tract and although its function remains unresolved, recent evidence supports its role as an antiproteinase. We have previously shown that it is over-expressed in lung diseases characterised by abnormalities of protease/antiprotease balance, including cystic fibrosis. Nothing is known about the distribution of WFDC2 in the mouse. In this study we have systematically localized the protein in normal adult mice as well in a number of mouse models characterised by epithelial remodelling. Strong WFDC2 staining is seen throughout the airway epithelium from the trachea down to the smallest airways. Staining is also seen in tracheal submucosal glands. No staining is seen in the peripheral lung. ...
http://erj.ersjournals.com/content/42/Suppl_57/P3886
Patent US5199427 - Multi-layered transtracheal caatheter - Google PatentsPatent US5199427 - Multi-layered transtracheal caatheter - Google Patents
A multi-layered transtracheal catheter. The transtracheal catheter has a multi-layer or double wall construction formed of two materials. One material is resistant to kinking. The other material is resistant to mucous buildup. Together, they form a catheter that can remain within the trachea for an extended period of time without needing to be removed for cleaning. The distal end of the catheter is deflected from the remainder of the catheter so that when the catheter is inside the trachea and held against the wall of the trachea, the distal end of the catheter is deflected from the wall so that the distal end is not in contact with the wall of the trachea. The result is reduced irritation to the trachea wall, reduced occlusion of the distal end by mucous buildup, and a more directed and efficient spray of material from the catheter into the right and left main skin bronchi of the lungs.
http://www.google.com/patents/US5199427?dq=Donato+M.+Fraioli
JCI - Citations to IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contractionJCI - Citations to IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction
mice. Likewise, knockdown of IQGAP1 in primary human airway smooth muscle cells increased RhoA activity. Immunoprecipitation studies indicated that IQGAP1 binds to both RhoA and p190A-RhoGAP, a GTPase-activating protein that normally inhibits RhoA activation. Proximity ligation assays in primary airway human smooth muscle cells and mouse tracheal sections revealed colocalization of p190A-RhoGAP and RhoA; however, these proteins did not colocalize in IQGAP1 knockdown cells or in ...
https://www.jci.org/articles/view/76658/citations
function of cilia in tracheafunction of cilia in trachea
Mucus, however, traps smaller particles like pollen and smoke. This mucus is a gel-like substance that is composed mainly of mucins, glycoproteins, and carbohydrates. A â ¦ These cilia direct the movement of molecules in a particular direction aids the function of excretion and secretion. In motile cilia, such as on the multiciliated epidermis (trachea, oviduct, or Xenopus tadpole skin), dynein motors generate ciliary movement, which drives fluid flow. Air that is inhaled may not necessarily be free of dust particles. The cilia In the female reproductive system, the cilia assist the movement of the ovum through the fallopian tube towards the uterus. im sure it isnt options c, d, or e. but i could be wrong. The ciliary apparatus is connected to cell cycle progression and proliferation, and cilia play a vital part in human and animal development and in everyday life. Cilia are broadly divided into two types. The function of cilia in the trachea and bronchi is to protect the airways from being ...
https://www.princo.cz/l6c8f/function-of-cilia-in-trachea-ef39ff
SilifkeSilifke
1913). "Seleucia Trachea". Catholic Encyclopedia. New York: Robert Appleton Company. Wikimedia Commons has media related to ... Seleucia Trachea, and Seleucia Tracheotis -. The city took its name from its founder, King Seleucus I Nicator. The ancient city ...
https://en.wikipedia.org/wiki/Silifke
ChondrolaryngoplastyChondrolaryngoplasty
"FFS: Trachea shave". 2005-06-21. Archived from the original on 2005-06-21. Retrieved 2021-06-28. "Facial Feminization Surgery ... as doing so can reduce the structure of the trachea and cause breathing difficulties.[citation needed] Most surgeons who ...
https://en.wikipedia.org/wiki/Chondrolaryngoplasty
W. H. PorterW. H. Porter
Larynx and Trachea. 1826. "Cases of Ligature of Subclavian and Right Carotid, and a Case of Tracheotomy", Dublin Hospital ... He was noted for his writing on the larynx and the trachea. "A Successful Case of Cynanache Maligna, with Trachaeotomy", Medico ...
https://en.wikipedia.org/wiki/W._H._Porter
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
A saber-sheath trachea may also be shown that is indicative of COPD. A CT scan is not routinely used except for the exclusion ... "saber sheath trachea , Search , Radiopaedia.org". Radiopaedia. Retrieved 13 August 2021. Vestbo J, Hurd SS, Agustí AG, et al. ( ...
https://en.wikipedia.org/wiki/Chronic_obstructive_pulmonary_disease
This Is How You DieThis Is How You Die
Candidiasis of the Trachea; Candidiasis of the Bronchi; Candidiasis of the Lungs; Kaposi's Sarcoma; Pneumonia; Tuberculosis; ...
https://en.wikipedia.org/wiki/This_Is_How_You_Die
Nasolacrimal ductNasolacrimal duct
... and Trachea". Boorman's Pathology of the Rat. Elsevier. pp. 391-435. doi:10.1016/b978-0-12-391448-4.00022-8. ISBN 978-0-12- ...
https://en.wikipedia.org/wiki/Nasolacrimal_duct
Common minke whaleCommon minke whale
Whale Trachea (Balaenoptera acutorostrata). Whale Tongue (Balaenoptera acutorostrata). Whale lung (Balaenoptera acutorostrata ...
https://en.wikipedia.org/wiki/Common_minke_whale
History of catecholamine researchHistory of catecholamine research
R. H. Kahn (1907). "Zur Physiologie der Trachea". Archiv für Anatomie und Physiologie, Archiv für Physiologie: 398-426. Hans ...
https://en.wikipedia.org/wiki/History_of_catecholamine_research
Exercise-induced pulmonary hemorrhageExercise-induced pulmonary hemorrhage
In the case where no blood is visible in the trachea, EIPH in the small airways may still be present and can be confirmed by a ... Blood can usually be detected in the trachea or bronchi for 1-3 days after an episode of EIPH, but may be present for up to a ... The amount of blood visible in the trachea at the time of examination is most commonly graded on a scale of 0 (no blood) to 4 ( ... Approximately 43 to 75% of horses have blood in the trachea and bronchi following a single post-race endoscopic examination. In ...
https://en.wikipedia.org/wiki/Exercise-induced_pulmonary_hemorrhage
Endoscopic laser cordectomyEndoscopic laser cordectomy
Surgery of larynx and trachea. Berlin, Germany: Springer-Verlag; 2010. 107-214. Oswal VH, Gandhi SS. Endoscopic laser ...
https://en.wikipedia.org/wiki/Endoscopic_laser_cordectomy
Anthony HollanderAnthony Hollander
First trachea transplant without immunosuppression , Eureka! Science News Anthony Hollander - University of Liverpool Webpage ...
https://en.wikipedia.org/wiki/Anthony_Hollander
ThyroplastyThyroplasty
Remacle, Marc; Eckel, Hans Edmund (8 January 2010). Surgery of Larynx and Trachea. Springer Science & Business Media. p. 59. ... Remacle, Marc; Eckel, Hans Edmund (8 January 2010). Surgery of Larynx and Trachea. Springer Science & Business Media. ISBN ... "Phonosurgery Phonosurgery" (PDF). Remacle, Marc; Eckel, Hans Edmund (8 January 2010). Surgery of Larynx and Trachea. Springer ...
https://en.wikipedia.org/wiki/Thyroplasty
Tracheal agenesisTracheal agenesis
In this case, the trachea is not attached to the oesophagus. In Faro type G, a segment of the trachea is absent, defining it as ... The trachea is absent proximally but there remains a short normal segment of the distal trachea. A tracheoesophageal fistula ... Faro type F describes the proximal absence of the trachea but the normal presence of the distal trachea. ... trachea and lungs. In mice, NK2 homeobox 1 null mutation results in a significantly shorter trachea, connected to the ...
https://en.wikipedia.org/wiki/Tracheal_agenesis
BronchioleBronchiole
The trachea divides into the left main bronchus which supplies the left lung, and the right main bronchus which supplies the ... Cross sectional cut of primary bronchiole Trachea Primary bronchus Lobar bronchus Segmental bronchus Bronchiole Alveolar duct ... ISBN 978-0-321-49804-5. Paxton, Steve; Peckham, Michelle; Knibbs, Adele (2003). "Respiratory: Trachea, bronchioles and bronchi ...
https://en.wikipedia.org/wiki/Bronchiole
Laryngeal papillomatosisLaryngeal papillomatosis
2017). "Tumours of the Hypopharynx, Larynx, Trachea and Parapharyngeal Space". World Health Organization Classification of Head ... Surgery of Larynx and Trachea. Berlin: Springer-Verlag Berlin Heidelberg. pp. 91-112. ISBN 9783540791355. OCLC 567327912. ...
https://en.wikipedia.org/wiki/Laryngeal_papillomatosis
TelocyteTelocyte
Zheng, Y.; Li, H.; Manole, C. G.; Sun, A.; Ge, J.; Wang, X. (October 2011). "Telocytes in trachea and lungs". Journal of ...
https://en.wikipedia.org/wiki/Telocyte
StridorStridor
... trachea or esophagus); ALL (T-cell ALL can present with mediastinal mass that compresses the trachea and causes inspiratory ... collapsed trachea). congenital anomalies of the airway are present in 87% of all cases of stridor in infants and children. ... vascular rings compressing the trachea; thyroiditis such as Riedel's thyroiditis; vocal cord palsy; tracheomalacia or ...
https://en.wikipedia.org/wiki/Stridor
Norwich TerrierNorwich Terrier
... narrow/misshapen tracheas; collapsing tracheas; stenotic nares (nasal passages that are too small); swollen tonsils; everted ... Also of a secondary magnitude there are instances of epilepsy, narrow tracheas, luxating patellas, hip dysplasia, mitral valve ...
https://en.wikipedia.org/wiki/Norwich_Terrier
Pulmonary alveolusPulmonary alveolus
"The trachea and the stem bronchi". Encyclopædia Britannica. Encyclopædia Britannica, Inc. Saladin KS (2007). Anatomy and ...
https://en.wikipedia.org/wiki/Pulmonary_alveolus
Sternohyoid muscleSternohyoid muscle
It runs lateral to the trachea. The sternohyoid muscle is supplied by a branch of the ansa cervicalis. The sternohyoid muscle ...
https://en.wikipedia.org/wiki/Sternohyoid_muscle
Karolinska InstituteKarolinska Institute
While Macchiarini admitted that the synthetic trachea did not work in the current state, he did not agree that trying it on ... "Trachea surgeon Macchiarini acted "without due care," but is not guilty of misconduct: Karolinska". Retraction Watch. 28 August ... "Reading about embattled trachea surgeon Paolo Macchiarini? Here's what you need to know". Retraction Watch. 12 February 2016. ... Macchiarini also claimed that the synthetic trachea had been tested on animals before using it on humans, something that could ...
https://en.wikipedia.org/wiki/Karolinska_Institute
Tukhchar massacreTukhchar massacre
The method was a pierced trachea. On 5 September 1999, two units of Chechen militants crossed into Dagestan, seizing the border ...
https://en.wikipedia.org/wiki/Tukhchar_massacre
Contact regionContact region
Tong Cui and Haifeng Zhao (2016). "An Efficient Virtual Trachea Deformation Model". MATEC Web of Conferences. EDP Sciences. 68 ...
https://en.wikipedia.org/wiki/Contact_region
Tracheal collapseTracheal collapse
Collapse of the cervical trachea or extrathoracic (in the neck) occurs during inspiration; collapse of the thoracic trachea or ... Extraluminal (outside the trachea) stenting is generally used only for tracheal collapse in the neck region. Intraluminal ... Severe cases can be treated with surgical implantation of a tracheal stent (inside or outside of the trachea) or prosthetic ... It is most commonly seen in the cervical trachea. Laryngeal saccules Fossum, Theresa W. (2002). "Surgical Management Of ...
https://en.wikipedia.org/wiki/Tracheal_collapse
Childrens Hospital of IllinoisChildren's Hospital of Illinois
Although the trachea implant was successful, she was unable to overcome her other health issues, and her lung function ... She received an artificial trachea that incorporated, "nanofiber mesh coated with Hannah's own bone marrow cells". Because the ... "Girl Dies After Groundbreaking Trachea Transplant". ABC News. Archived from the original on 14 October 2019. Retrieved 29 July ... and the first bioengineered trachea transplant in the world. It was the first stem cell procedure of any kind at the Catholic ...
https://en.wikipedia.org/wiki/Children's_Hospital_of_Illinois
Artificial organArtificial organ
The field of artificial tracheas went through a period of high interest and excitement with the work of Paolo Macchiarini at ... As of 2017 engineering a trachea-a hollow tube lined with cells-had proved more challenging than originally thought; challenges ... Den Hondt M, Vranckx JJ (February 2017). "Reconstruction of defects of the trachea". Journal of Materials Science. Materials in ... as well as the rotational and longitudinal movement the trachea undergoes. It is also possible to construct and install an ...
https://en.wikipedia.org/wiki/Artificial_organ
Harvard BioscienceHarvard Bioscience
They produce trachea scaffolds and bioreactors. Biostage has litigation over wrongful death pending that may affect Harvard ...
https://en.wikipedia.org/wiki/Harvard_Bioscience
Recurrent laryngeal nerveRecurrent laryngeal nerve
After branching, the nerves typically ascend in a groove at the junction of the trachea and esophagus.: 1346-1347 They then ... They both travel alongside the trachea. Additionally, the nerves are among the few nerves that follow a recurrent course, ... There is suspected variability in the configuration of these branches to the cardiac plexus, trachea, esophagus and inferior ... 86-88 Parasympathetic fibers to segments of the trachea and esophagus in the neck originate in the dorsal nucleus of the vagus ...
https://en.wikipedia.org/wiki/Recurrent_laryngeal_nerve
OnychophoraOnychophora
... the velvet worms are unable to control the openings of their tracheae; the tracheae are always open, entailing considerable ... The number of "tracheae bundles" thus formed is on average around 75 bundles per body segment; they accumulate most densely on ... The tracheae originate at tiny openings, the spiracles, which themselves are clustered together in dent-like recesses of the ... However, of most importance is gas exchange via fine unbranched tubes, the tracheae, which draw oxygen from the surface deep ...
https://en.wikipedia.org/wiki/Onychophora
Tracheoesophageal septumTracheoesophageal septum
It divides the oesophagus from the trachea. This is complete by 6 weeks of gestation. It divides the foregut tube: the ... It divides the oesophagus from the trachea during prenatal development. Developmental abnormalities can lead to a ... The tracheoesophageal septum divides the oesophagus from the trachea during prenatal development. Developmental abnormalities ...
https://en.wikipedia.org/wiki/Tracheoesophageal_septum
Trachea Foreign Bodies: Practice Essentials, Pathophysiology, EtiologyTrachea Foreign Bodies: Practice Essentials, Pathophysiology, Etiology
encoded search term (Trachea Foreign Bodies) and Trachea Foreign Bodies What to Read Next on Medscape ... Trachea Foreign Bodies Updated: Sep 21, 2022 * Author: Neil Gildener-Leapman, MD; Chief Editor: Steven C Dronen, MD, FAAEM more ...
http://emedicine.medscape.com/article/764615-overview
https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-tracheahttps://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea
The Tender Human Trachea. Download Comic Close Download Menu ... The Tender Human Trachea. Share News Close Share Menu * Tweet * ... https://www.penny-arcade.com/news/post/2008/08/01/the-tender-human-trachea ... https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea ... https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea ...
https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea
Articles, tagged with tracheaArticles, tagged with "trachea"
To cite an instance, lets say your surgeon plans to carry out a bilateral neck dissection with thyroidectomyand trachea ...
http://www.articlealley.com/tags-63869.html
Vertebrate tracheaVertebrate trachea
... Conducting passages. Laryngoscopic view of interior of larynx. (Trachea labeled at bottom ... The epiglottis is the flap that closes the trachea during swallowing to prevent swallowed matter from entering the trachea. ... The esophagus lies posteriorly to the trachea. The cartilaginous rings are incomplete because this allows the trachea to ... Trachea The tracheartes, or windpipe, is a tube that has an inner diameter of about 20-25 mm and a length of about 10-16cm. It ...
https://www.bionity.com/en/encyclopedia/Vertebrate_trachea.html
What to Know About a Collapsing Trachea in DogsWhat to Know About a Collapsing Trachea in Dogs
And what is the prognosis for dogs with a collapsing trachea? Get the facts here. ... First, what is a trachea and what is a collapsing trachea in dogs?. First, what is the trachea? Photography ©bymuratdeniz , ... What is a collapsing trachea in dogs? And what is the prognosis for dogs with a collapsing trachea? Get the facts here. ... Is there a cure for a collapsing trachea in dogs?. Unfortunately, collapsing trachea in dogs is not curable. Even with surgery ...
https://www.dogster.com/dog-health-care/what-to-know-about-a-collapsing-trachea-in-dogs
Larry Nixed, Trachea Trixed, Slavs and TatarsLarry Nixed, Trachea Trixed, Slavs and Tatars
Trachea Trixed looks at various attempts to Cyrillicize sounds or phonemes that did not previously exist in the Russian ... Larry Nixed, Trachea Trixed looks at various attempts to Cyrillicize sounds or phonemes that did not previously exist in the ...
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Stem Cell Trachea Transplant - Life IssuesLife IssuesStem Cell Trachea Transplant - Life IssuesLife Issues
In November doctors in Sweden used the patient s own bone marrow stem cells to build a new trachea to replace the cancerous ... It was then transplanted into his body after doctors removed the cancerous trachea. Anti-rejection drugs weren t needed since ...
https://lifeissues.org/2012/02/stem-cell-trachea-transplant/
trachea replacement Archives - Jill Stanek - Jill Stanek
Entries Tagged trachea replacement. Jivin J s Life Links 8-4-10. by JivinJ, host of the blog, JivinJehoshaphat In Los Angeles ...
https://www.jillstanek.com/tag/trachea-replacement/
Silkworm trachea | 2004 Photomicrography Competition | Nikons Small WorldSilkworm trachea | 2004 Photomicrography Competition | Nikon's Small World
Articles and Tutorials on Optical Microscopy, Photomicrography, and Digital ...
https://www.nikonsmallworld.com/galleries/2004-photomicrography-competition/silkworm-trachea
Mouse CD1 Trachea Paraffin Sections | MP-602 | ZYAGENMouse CD1 Trachea Paraffin Sections | MP-602 | ZYAGEN
Mouse CD1 Trachea Paraffin Sections from ZYAGEN. Cat Number: MP-602. UK & Europe Distribution. ... Mouse CD1 Trachea Paraffin Sections , MP-602 Zyagen Mouse Sections Mouse CD1 Trachea Paraffin Sections , MP-602. (No reviews ... Mouse CD1 Trachea Paraffin Sections , MP-602 , Zyagen. Tissues are fixed in 10% neutral buffered formalin, embedded in paraffin ... Mouse CD1 Trachea Frozen Sections , MF-602 , ZyagenTissues are freshly snapped frozen in OCT blocks, sectioned at a thickness ...
https://delos.info/mouse-cd1-trachea-paraffin-sections-mp-602/
Barkworthies Beef Trachea Dog Treat 6Barkworthies Beef Trachea Dog Treat 6"
Buy Barkworthies Beef Trachea 6 at PetGuys.com, where you find pet supplies at wholesale prices. Fast shipping and excellent ... Beef Trachea.. * Ingredients listed are for informational purposes only and are subject to change by the manufacturer. Always ... Barkworthies Beef Trachea is an all natural, highly digestible dog chew with fat trimmings left on for an enticing and ...
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Wegeners granulomatosis: isolated involvement of the trachea and larynx. | Annals of the Rheumatic DiseasesWegener's granulomatosis: isolated involvement of the trachea and larynx. | Annals of the Rheumatic Diseases
A 26 year old man with subacute hoarseness and stridor was shown to have Wegeners granulomatosis isolated to the trachea and ...
https://ard.bmj.com/content/46/8/628
Lungs and Trachea with Lobes Highlighted Image - Understand.comLungs and Trachea with Lobes Highlighted Image - Understand.com
bronchi, inferior, inferior lobe, left inferior lobe, left lobe, left superior lobe, lobe, lobes, lung, lungs, middle, middle lobe, organs, respiratory system, right inferior lobe, right lobe, right middle lobe, right superior lobe, superior, superior lobe, trachea
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Kennel cough vs. collapsed trachea - YorkieTalk.com Forums - Yorkshire Terrier CommunityKennel cough vs. collapsed trachea - YorkieTalk.com Forums - Yorkshire Terrier Community
collapsed trachea. To make a long story as short as possible as I am just needing opinions.. Got my baby from a puppymill in ... The vet noticed a very slight collapsed trachea. But he said it was so slight that it wasnt a thing to make him go AH HA, ... My regular vet then tells me well, it could be the collapsed trachea and there is nothing you can do about that. I informed ... Neither of my babies have collapsed trachea (knock on wood) but they both had kennel cough. Actually, Willow still does. When ...
https://www.yorkietalk.com/forums/sick-injured-emergencies-talk/73142-kennel-cough-vs-collapsed-trachea.html
Leufen Aerstent Trachea Bronchus: Complete silicon cover | KapitexLeufen Aerstent Trachea Bronchus: Complete silicon cover | Kapitex
Leufen Aerstent Trachea Bronchus. Leufen Aerstent Trachea Bronchus. The special end design and the strong radial force keep the ... Leufen Aerstent Trachea Bronchus. The special end design and the strong radial force keep the stents in position to avoid ... The new Y Carina stent is used to bridge benign or malignant stenosis in the trachea and in the right or left bronchus. ... The Montgomery® Safe-T-Tube™ is designed to maintain an adequate airway as well as to provide support in the stenotic trachea ...
https://www.kapitex.com/product-category/airway-management/stents/leufen-aerstent-trachea-bronchus-complete-silicon-cover/?sku=2155
The Metabolism of 4,5-Dihydro-4,5-dihydroxybenzo[a]pyrene by Short-Term Organ Cultures of Hamster Trachea and Lung |...The Metabolism of 4,5-Dihydro-4,5-dihydroxybenzo[a]pyrene by Short-Term Organ Cultures of Hamster Trachea and Lung |...
The Metabolism of 4,5-Dihydro-4,5-dihydroxybenzo[a]pyrene by Short-Term Organ Cultures of Hamster Trachea and Lung BRIAN P. ... pyrene by Short-Term Organ Cultures of Hamster Trachea and Lung. Biochem Soc Trans 1 October 1977; 5 (5): 1368-1370. doi: https ...
https://portlandpress.com/biochemsoctrans/article-abstract/5/5/1368/90384/The-Metabolism-of-4-5-Dihydro-4-5-dihydroxybenzo-a?redirectedFrom=PDF
Diagnosis and Treatment of Diseases of the Trachea and Bronchi., Archives of Otolaryngolog | 10.1001/archotol.1960...Diagnosis and Treatment of Diseases of the Trachea and Bronchi., Archives of Otolaryngolog | 10.1001/archotol.1960...
Diagnosis and Treatment of Diseases of the Trachea and Bronchi.. Diagnosis and Treatment of Diseases of the Trachea and Bronchi ... Diagnosis and Treatment of Diseases of the Trachea and Bronchi.. Archives of Otolaryngolog. , Volume 72 (4) - Oct 1, 1960 ... Diagnosis and Treatment of Diseases of the Trachea and Bronchi.. Abstract. In less than one hundred pages of type and using 35 ... "Diagnosis and Treatment of Diseases of the Trachea and Bronchi.." Archives of Otolaryngolog 72.4 (1960): 561-561.. Reference ...
https://www.deepdyve.com/lp/american-medical-association/diagnosis-and-treatment-of-diseases-of-the-trachea-and-bronchi-KGfBydbIIN
Návody | TracheaNávody | Trachea
Trachea OS. Reklamace a všeobecné obchodní podmínky. Výrobní možnosti Trachea. Provozní doba konce roku 2022 a začátek roku ... 420 573 502 111 trachea@trachea.cz. Kariéra GDPR Nastavení preferencí cookies ...
https://www.trachea.cz/cz/b2b/navody-na-udrzbu
Trachea ShaveTrachea Shave
Board certified Jeffrey Spiegel MD specializes in trachea shave procedures to remove the appearance of an Adams apple from the ... Procedure: Trachea Shave. Source: Real Self. After doing a lot of research I decided to have a trachea shave and vocal ... Trachea Shave Boston. A trachea shave can be an effective, satisfying and long-lasting solution to a large Adams apple for men ... What is a Trachea Shave Procedure?. A trachea shave procedure is known in the medical community as a chondrolaryngoplasty. ...
https://www.drspiegel.com/facial-feminization-surgery-boston/ffs-procedures/trachea-shave/
Spasmolytic Effects of Aqueous Extract of Mixture from Aframomumum Melegueta (K Schum) - Citrus Aurantifolia (Christm and...Spasmolytic Effects of Aqueous Extract of Mixture from Aframomumum Melegueta (K Schum) - Citrus Aurantifolia (Christm and...
These results clearly show the relaxing effect of the aqueous extract on the isolated rat trachea. This effect involved some β- ... Keywords: Aframomum melegueta, Citrus aurantifolia, extract, bronchodilatory, spasmolytic, Rat trachea. Abstract. The ... after a pre contraction of the trachea by acetylcholine (10-5 M). With propranolol (10-6 M), the spasmolytic activity of the ... mixture were tested on isolated rat trachea. Inhibition of the contraction was observed the in presence of the AMCA (EC 50 = ...
https://www.ajol.info/index.php/ajtcam/article/view/73147
CT of the Trachea: A Practical Approach - Part 2 - Lecture - Medical Imaging | CTisus Advanced Diagnostic Imaging | CT ScanningCT of the Trachea: A Practical Approach - Part 2 - Lecture - Medical Imaging | CTisus Advanced Diagnostic Imaging | CT Scanning
Weekly Lectures ❳ CHEST ❳ CT of the Trachea: A Practical Approach - Part 2 ...
https://www.ctisus.com/media/2021/09/27/ct-of-the-trachea-a
Endothelins: functional and autoradiographic studies in guinea pig trachea - Tschirhart EricEndothelins: functional and autoradiographic studies in guinea pig trachea - Tschirhart Eric
ET(16-21) and ET(16-21)-NH2 were less potent agonists than the ETs in guinea pig trachea and 10 microM ET(16-21) was unable to ... ETs and sarafotoxin S6b (0.1-100 nM) induced potent contractile responses in guinea pig trachea with EC50 values ranging from ... en] Animals ; pharmacology ; metabolism ; Trachea ; Muscle, Smooth ; Muscle Contraction ; Male ; Guinea Pigs ; Glycopeptides ; ... these results suggest that the C-terminal hexapeptide of ET-1 cannot be used to classify ET receptors in guinea pig trachea. ...
https://orbilu.uni.lu/handle/10993/5754
Barkworthies Beef Trachea Dog Chew, 6-inchBarkworthies Beef Trachea Dog Chew, 6-inch
Barkworthies Beef trachea has the health benefits of a naturally occurring form of glucosamine and chondroitin for strong ... sturdy all-natural dog chew with fat trimmings left on making Barkworthies Beef Trachea both enticing and delicious! ... Barkworthies Beef Trachea 6-inch is a great size for small to large dogs. Barkworthies Beef Trachea are longer lasting for your ... Barkworthies Beef Trachea is FDA approved and produced from free-range, grass-fed Briazilian cattle. Brazil is known for their ...
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Propofol Preferentially Relaxes Neurokinin Receptor-2-induced Airway Smooth Muscle Contraction in Guinea Pig Trachea |...Propofol Preferentially Relaxes Neurokinin Receptor-2-induced Airway Smooth Muscle Contraction in Guinea Pig Trachea |...
airway device, guinea, propofol, smooth muscle, tracheal ring, thiopental, trachea, anesthetics, intravenous, acetylcholine, ... Propofol Preferentially Relaxes Neurokinin Receptor-2-induced Airway Smooth Muscle Contraction in Guinea Pig Trachea Neil R. ... Tracheas were promptly removed and dissected into two closed cartilaginous ring units with mucosa, connective tissue, and ... Kummer W, Fischer A, Kurkowski R, Heym C: The sensory and sympathetic innervation of guinea-pig lung and trachea as studied by ...
https://pubs.asahq.org/anesthesiology/article/112/6/1335/10280/Propofol-Preferentially-Relaxes-Neurokinin
What Does The Trachea Do? - BlurtitWhat Does The Trachea Do? - Blurtit
The trachea is a pipe in your throat. Its lined with mucus so it can trap foriegn objects. ... The trachea is a very important part of the respiratory system in animals. The trachea is seen in both... ... Trachea is basically a tube that commences at the Larynx and divides into primary Bronchi, allowing air passage to the lungs.. ... The trachea is a windpipe that carries the air you breathe in from your nose and mouth to the lungs. ...
https://science.blurtit.com/424286/what-does-the-trachea-do
Canine Caviar Water Buffalo Buffaroos Trachea Dog Treats, 12-Inch, Case of 12 | NaturalPetWarehouse.comCanine Caviar Water Buffalo Buffaroos Trachea Dog Treats, 12-Inch, Case of 12 | NaturalPetWarehouse.com
Buy Canine Caviar Water Buffalo Buffaroos Trachea Dog Treats, 12-Inch, Case of 12 at NaturalPetWarehouse.com. Free Shipping on ... Canine Caviars Buffaroos trachea dog treats are part of our family of dental treats for dogs. These trachea dog treats help in ... Water buffalo trachea and our other Water buffalo dog treats help fight tartar to keep your dog with a beautiful smile. Trachea ... Canine Caviar Water Buffalo Buffaroos Trachea Dog Treats, 12", Case of 12. 0 Review(s) 0 0 5 ...
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Glomus tumor of the trachea<...Glomus tumor of the trachea<...
title = "Glomus tumor of the trachea",. abstract = "Introduction: We describe a primary glomus tumor of the trachea. Methods: A ... Okereke, I. C., Sheski, F. D., & Cummings, O. W. (2011). Glomus tumor of the trachea. Journal of Thoracic Oncology, 6(7), 1290- ... Okereke, IC, Sheski, FD & Cummings, OW 2011, Glomus tumor of the trachea, Journal of Thoracic Oncology, vol. 6, no. 7, pp. ... Okereke, Ikenna C. ; Sheski, Francis D. ; Cummings, Oscar W. / Glomus tumor of the trachea. In: Journal of Thoracic Oncology. ...
https://researchexperts.utmb.edu/en/publications/glomus-tumor-of-the-trachea
Redbarn Trachea Ring - in Gap, PA - Stoltzfus Feed and Supply
Redbarns Beef Trachea is a tasty single-ingredient treat for beef-loving pups. Packed with protein, beef trachea is naturally ... Redbarns Beef Trachea is a tasty single-ingredient treat for beef-loving pups. Packed with protein, beef trachea is naturally ... Our beef trachea is completely free of grains and gluten, so dogs can enjoy without the addition of wheat, corn, or soy - just ... Available as a ring, bits, and cuts, Redbarns Beef Trachea Treats feature a crunchy texture that supports dental health and ...
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ValueBull Beef Trachea Dog Chews, 1-4 Inch, All Natural, 20 Pounds reviews | Value Pet SuppliesValueBull Beef Trachea Dog Chews, 1-4 Inch, All Natural, 20 Pounds reviews | Value Pet Supplies
ValueBull Beef Trachea Bites, Premium 1-4 Inch, All Natural Dog Chews are hollow chews with long-lasting flavor. Each trachea ... Ingredients: Beef Trachea. Origin: Brazil, India & Turkey. Supervision is recommended when giving your dog any treat. Always ... These tasty crunchy beef chews will be a hit with your dog! ValueBull Beef Trachea Bites, Premium 1-4 Inch, All Natural Dog ... ValueBull Beef Trachea Dog Chews, 1-4 Inch, All Natural, 20 Pounds - ValueBullSKU: VP04851-20LB ...
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Functions of the Trachea and Other Respiratory Organs | New Health GuideFunctions of the Trachea and Other Respiratory Organs | New Health Guide
What are the functions of the trachea? Learn about this important structure here. ... Without trachea, there is no way humans can breathe. ... Diseases with Trachea. Problems with the trachea will affect ... Functions of the Trachea and Other Respiratory Organs. The trachea, also called the windpipe, is a 4 inch long tube that ... The trachea also plays an important role in the digestive process. Your trachea is connected to the tubing system that makes it ...
https://www.newhealthguide.org/Trachea-Function.html
WindpipeBronchiLungsLungEsophagusAirwayTracheal StenosisBarkworthies Beef TracheaDiseasesGuinea pig tracheaFunctions of tracheaBronchusDistalCartilageLumenNeckContractionBronchialLaryngealGreat vesselsProteinTreatsTreatTISSUEChondroitinThoracicStenosisRigidCancerousBeefVocalSurgeryCoughCarinaPathologySmoothProcedureAbstractInnominateClinical
Windpipe5
  • The trachea - more commonly known as the "windpipe" - carries oxygen from the environment into the lungs. (dogster.com)
  • The trachea, also called the windpipe, is a 4 inch long tube that measures a diameter of less than one inch. (newhealthguide.org)
  • As you can see in the trachea pictures, the windpipe is structurally composed of incomplete rings, resembling the letter C in English which range from 15 to 20 in number. (organsofthebody.com)
  • Bronchioles are air passages inside the lungs that branch off like tree limbs from the bronchi-the two main air passages into which air flows from the trachea (windpipe) after being inhaled through the nose or mouth. (kembrel.com)
  • It then spreads down into the windpipe (trachea) and lungs (lower respiratory tract). (ahealthyme.com)
Bronchi9
  • Diagnosis and Treatment of Diseases of the Trachea and Bronchi. (deepdyve.com)
  • Trachea is basically a tube that commences at the Larynx and divides into primary Bronchi, allowing air passage to the lungs. (blurtit.com)
  • What Is The Function Of The Cartilage Rings In The Trachea And The Bronchi? (blurtit.com)
  • When you inhale air, oxygen travels down your trachea, then to the bronchi, then to the bronchioles, and then the alveoli. (newhealthguide.org)
  • Hyaline cartilage provides structural support in the respiratory system (larynx, trachea and bronchi). (histologyguide.com)
  • The trachea ends caudally with a crest, called the carina, which divides and channels the airflow into the two mainstem bronchi. (bsavalibrary.com)
  • The bronchi (or bronchus) are the air passages into the lungs that begin at the end of the trachea. (kembrel.com)
  • Pulmonology is concerned with the respiratory organs (trachea, bronchi, lungs, pleurae) and their diseases. (medcentras.lt)
  • It presents bronchoscopy images of larynx, trachea, left and right main bronchi, and distal airway. (bvsalud.org)
Lungs6
  • Endotracheal intubation is the medical procedure of inserting an artificial tube into the trachea to provide a secure route for ventilating the lungs. (bionity.com)
  • By coughing, the trachea is trying to expel those objects thereby allowing air to get to the lungs. (newhealthguide.org)
  • On the other hand, when the air is too cold, your trachea can warm the air before it enters into your lungs, thus promoting a thermo balance. (newhealthguide.org)
  • They may reappear after treatment, undergo malignant transformation, and/or occasionally spread to the trachea or lungs. (merckmanuals.com)
  • The area between the lungs is known as the mediastinum, and it is within this region that the heart and its great vessels, the esophagus, trachea, and lymph nodes reside. (cdc.gov)
  • Hamsters infected with the G614 variant produced higher infectious titers in the nasal washes and trachea, but not lungs, confirming clinical evidence that the D614G mutation enhances viral loads in the upper respiratory tract of COVID-19 patients and may increases transmission. (cdc.gov)
Lung3
  • Pulmosan thrips eliminates the trachea and lung mites in canaries, finches, tropical birds and aviary. (mascotasalfalfa.com)
  • What it amounts to, especially in these types of respiratory cases where there is a chronic cough, maybe there has been some diagnoses done and they are influenza negative but they still have a chronic dry cough, especially the nursery phase, we're encouraging people to submit trachea along with lung samples. (farmscape.ca)
  • It's not on the top of mind for practitioners to do but, if we would get trachea samples as well as lung samples, we think that that will help us to better identify the cause of those types of chronic coughing episodes. (farmscape.ca)
Esophagus3
  • The esophagus lies posteriorly to the trachea. (bionity.com)
  • The cartilaginous rings are incomplete because this allows the trachea to collapse slightly to allow food to pass down the esophagus . (bionity.com)
  • The channel connects the esophagus and trachea. (newhealthguide.org)
Airway4
  • In humans there are about 15 - 20 incomplete C-shaped cartilaginous rings which reinforces the anterior and lateral sides of the trachea to protect and maintain the airway open. (bionity.com)
  • The Montgomery® Safe-T-Tube™ is designed to maintain an adequate airway as well as to provide support in the stenotic trachea that has been reconstituted or reconstructed. (kapitex.com)
  • ET(16-21) and ET(16-21)-NH2 were less potent agonists than the ETs in guinea pig trachea and 10 microM ET(16-21) was unable to inhibit [125I]ET-1 binding in guinea pig airway smooth muscle. (uni.lu)
  • The relationship between epithelial bioelectric events and epithelium-dependent relaxant and contractile responses of airway smooth muscle in response to hyperosmolar and hypo-osmolar solutions was investigated in guinea pig isolated trachea. (cdc.gov)
Tracheal Stenosis1
  • Postmortem (A) coronal and (B) sagittal micro-CT images, at 28 micron (0.028 mm) resolution of the excised trachea reveals a short segment, tight tracheal stenosis (red square bracket). (bmj.com)
Barkworthies Beef Trachea6
  • Barkworthies Beef Trachea is an all natural, highly digestible dog chew with fat trimmings left on for an enticing and delicious flavor! (petguys.com)
  • Barkworthies Beef Trachea offers a 100% digestible, sturdy all-natural dog chew with fat trimmings left on making Barkworthies Beef Trachea both enticing and delicious! (whitedogbone.com)
  • Barkworthies Beef trachea has the health benefits of a naturally occurring form of glucosamine and chondroitin for strong healthy joints. (whitedogbone.com)
  • Barkworthies Beef Trachea 6-inch is a great size for small to large dogs. (whitedogbone.com)
  • Barkworthies Beef Trachea are longer lasting for your slightly aggressive chewer and are 100% digestible dog chews, making them a healthy alternative to a traditional rawhide chew. (whitedogbone.com)
  • Barkworthies Beef Trachea is FDA approved and produced from free-range, grass-fed Briazilian cattle. (whitedogbone.com)
Diseases2
  • As with other organs of your body , trachea is also vulnerable to a number of diseases that are commonly known as respiratory disorders, viz. (organsofthebody.com)
  • What diseases or disorders affect the trachea? (kembrel.com)
Guinea pig trachea3
  • en] The presence of binding sites for [125I]endothelin-1 and the contractile activities of endothelins (ETs) and sarafotoxin S6b and the endothelin fragment ET(16-21) were investigated in guinea pig trachea. (uni.lu)
  • ETs and sarafotoxin S6b (0.1-100 nM) induced potent contractile responses in guinea pig trachea with EC50 values ranging from 1.57 to 12.97 nM. (uni.lu)
  • Therefore, these results suggest that the C-terminal hexapeptide of ET-1 cannot be used to classify ET receptors in guinea pig trachea. (uni.lu)
Functions of trachea1
Bronchus1
  • The new Y Carina stent is used to bridge benign or malignant stenosis in the trachea and in the right or left bronchus. (kapitex.com)
Distal2
  • 10.4 (a) Lateral tracheal radiograph of a 12-year-old Labrador Retriever (with dilated cardiomyopathy) with flexed neck position, resulting in dorsal deviation of the distal trachea. (bsavalibrary.com)
  • In follow-up, the patient presented with dyspnea related to two areas of stenosis, one at the level of her stoma and one at the distal trachea. (scirp.org)
Cartilage4
  • With collapsing trachea in dogs, the cartilage rings become malacic (or soft) as a dog ages. (dogster.com)
  • Instead of maintaining a rigid shape, the cartilage becomes soft and fails to keep the trachea open. (dogster.com)
  • The trachea is held in place by hyaline cartilage in the form of you-Shaped cartilaginous rings surrounding. (blurtit.com)
  • The trachea location can be traced in the chest region, and it is made of soft bony material, called cartilage that allows great amount of flexibility for the efficient performance of its essential tasks. (organsofthebody.com)
Lumen4
  • This contracts reducing the size of the lumen of the trachea to increase the air flow rate during coughing. (bionity.com)
  • Tracheotomy is a surgical procedure of making an opening in the front of the neck that extends to the lumen of the trachea, a short tube called a tracheostomy tube is inserted through this opening, entering below the level of the larynx and vocal cords . (bionity.com)
  • The cross-sectional area of the trachea at the level of the sixth cervical vertebra is reduced due to the invagination of the dorsal trachealis muscle into the lumen. (bsavalibrary.com)
  • Formation of large tumor (benign or cancerous) in the lumen of trachea may cause the blockage of the air passage and death of the victim due to chocking. (organsofthebody.com)
Neck1
Contraction1
  • Inhibition of the contraction was observed the in presence of the AMCA (EC 50 = 1.80 ± 0.48 mg/mL) after a pre contraction of the trachea by acetylcholine (10 -5 M). With propranolol (10 -6 M), the spasmolytic activity of the mixture was inhibited and the concentration-response curve shifted to the right. (ajol.info)
Bronchial2
  • A patient with a primary carcinoid tumour of trachea treated as a case of bronchial asthma for over a decade, is presented. (who.int)
  • The trachea is a semi-rigid air-filled tube that connects the larynx with the bronchial system. (bsavalibrary.com)
Laryngeal1
  • Laryngeal papilloma cancer Coblation treatment for what is laryngeal papilloma papillomatosis papiloma en perros en la boca tratamiento Laryngeal papilloma virus. (granturieuropene.ro)
Great vessels1
  • Clinical examination suggested posterior dislocation of the medial end of the clavicle with possible encroachment of the great vessels, trachea and the oesophagus. (ispub.com)
Protein2
  • Trachea dog treats are a part of our family of high protein dog treats which is an essential component to any dog's diet. (naturalpetwarehouse.com)
  • Packed with protein, beef trachea is naturally high in chondroitin and glucosamine, supporting dogs' healthy joints. (stoltzfusfeedandsupply.com)
Treats4
  • Canine Caviar's Buffaroos trachea dog treats are part of our family of dental treats for dogs. (naturalpetwarehouse.com)
  • These trachea dog treats help in tartar removal. (naturalpetwarehouse.com)
  • Water buffalo trachea and our other Water buffalo dog treats help fight tartar to keep your dog with a beautiful smile. (naturalpetwarehouse.com)
  • Available as a ring, bits, and cuts , Redbarn's Beef Trachea Treats feature a crunchy texture that supports dental health and serves as a boredom-busting snack! (stoltzfusfeedandsupply.com)
Treat4
  • If collapsing trachea is heavily suspected but not confirmed, your veterinarian has two options: treat the symptoms and see if they respond, or refer for more advanced diagnostics. (dogster.com)
  • In many cases, owners opt to treat the symptoms of collapsing trachea in dogs medically and monitor the dog. (dogster.com)
  • Redbarn's Beef Trachea is a tasty single-ingredient treat for beef-loving pups. (stoltzfusfeedandsupply.com)
  • With no preservatives, additives, cereals or fillers, beef trachea is a brilliant complimentary treat to raw feeding, whether it being. (carnesnatural.com)
TISSUE2
  • He claimed that, when he started the tracheostomy and removed tissue from the trachea, the weakness and injury in the innominate artery resulted in a rupture of the blood vessel, which caused a "horrendous gush of blood. (harvard.edu)
  • Swine Veterinarians and swine producers are being advised to include tissue from the trachea when submitting samples to the veterinary diagnostic labs for the diagnosis of respiratory infections. (farmscape.ca)
Chondroitin2
  • Each trachea is a great source of glucosamine and chondroitin, which are natural supplements that help support your dog's joints. (valuepetsupplies.com)
  • Beef trachea has the health benefits of a naturally occurring form of glucosamine and chondroitin for strong healthy joints, they also serve as a great dental chews by removing food residue and plaque. (loyalcompanion.com)
Thoracic1
  • Note the divergence of the trachea from the thoracic vertebra, and narrowing of the most caudal part of the trachea. (bsavalibrary.com)
Stenosis2
  • Axial CT sections obtained (B) above, (C) at the level of the stenosis and (D) inferior to the stenosis show the relative narrowing of the trachea in relation to the intubated and non-stenosed sections (arrows). (bmj.com)
  • Comparative axial sections through the trachea at the level of stenosis (white arrow) at both (C) micro-CT imaging and (D) histopathological examination (alcian blue and periodic acid-Schiff staining) show fibrosis of the tracheal wall and loss of mucous glands (left column images). (bmj.com)
Rigid2
  • A stent is a rigid implant that holds the trachea open. (dogster.com)
  • This is when our trachea is floppy and soft instead of rigid. (newhealthguide.org)
Cancerous2
  • In November doctors in Sweden used the patient 's own bone marrow stem cells to build a new trachea to replace the cancerous one. (lifeissues.org)
  • It was then transplanted into his body after doctors removed the cancerous trachea. (lifeissues.org)
Beef5
  • Beef Trachea. (petguys.com)
  • Barkworthies 6" Beef Trachea also serve as a great dental chews by removing food residue and plaque. (whitedogbone.com)
  • Our beef trachea is completely free of grains and gluten, so dogs can enjoy without the addition of wheat, corn, or soy - just beef! (stoltzfusfeedandsupply.com)
  • ValueBull Beef Trachea Dog Chews, 1-4. (valuepetsupplies.com)
  • ValueBull Beef Trachea Bites, Premium 1-4 Inch, All Natural Dog Chews are hollow chews with long-lasting flavor. (valuepetsupplies.com)
Vocal2
  • After doing a lot of research I decided to have a trachea shave and vocal feminization surgery with Dr. Spiegel. (drspiegel.com)
  • Apart from just gaseous exchange, it is also involved in the production of vocal sounds as one of the secondary trachea functions. (organsofthebody.com)
Surgery1
  • Surgery or a stent is required to improve breathing by opening the trachea. (newhealthguide.org)
Cough3
  • Your vet will try to elicit the cough by deeply pressing on the trachea and rubbing vigorously. (dogster.com)
  • Neither of my babies have collapsed trachea (knock on wood) but they both had kennel cough. (yorkietalk.com)
  • The incidence of cough at extubation of the trachea can be reduced. (arwy.org)
Carina1
  • The trachea ends with the carina at the level of the fifth intercostal space (arrowhead). (bsavalibrary.com)
Pathology1
  • Conclusion: The final pathology was consistent with glomus tumor of the trachea. (utmb.edu)
Smooth1
  • Changes in smooth muscle tone during osmotic challenge in relation to epithelial bioelectric events in guinea pig isolated trachea. (cdc.gov)
Procedure2
  • What is a trachea shave procedure? (drspiegel.com)
  • A trachea shave procedure is known in the medical community as a chondrolaryngoplasty. (drspiegel.com)
Abstract1
  • abstract = "Introduction: We describe a primary glomus tumor of the trachea. (utmb.edu)
Innominate1
  • Computerized Tomograms (CT) revealed posterior dislocation of the medial end of the clavicle with a superior mediastinal haematoma and compression of the innominate vein with pressure on the oesophagus and trachea (Fig.2). (ispub.com)
Clinical1
  • Larry Nixed, Trachea Trixed looks at various attempts to Cyrillicize sounds or phonemes that did not previously exist in the Russian Cyrillic alphabet, one of many attempts to extend or embed Soviet influence, with a decidedly more sensuous, if not sexualized, approach to the traditionally cold, clinical approach of linguistics. (mottodistribution.com)
Trachea Foreign Bodies: Practice Essentials, Pathophysiology, Etiology
Trachea Foreign Bodies: Practice Essentials, Pathophysiology, Etiology (emedicine.medscape.com)
Injuries from Batteries Among Children Aged |13 Years - United States, 1995-2010
Injuries from Batteries Among Children Aged |13 Years - United States, 1995-2010 (cdc.gov)
Preventing Chronic Disease | Using Current Smoking Prevalence to Project Lung Cancer Morbidity and Mortality in Georgia by 2020...
Preventing Chronic Disease | Using Current Smoking Prevalence to Project Lung Cancer Morbidity and Mortality in Georgia by 2020... (cdc.gov)
Appendix A: Word Parts and What They Mean: MedlinePlus
Appendix A: Word Parts and What They Mean: MedlinePlus (medlineplus.gov)
Croup: MedlinePlus
Croup: MedlinePlus (medlineplus.gov)
Tracheal Disorders | Tracheostomy | MedlinePlus
Tracheal Disorders | Tracheostomy | MedlinePlus (medlineplus.gov)
Caring for Cancer Survivors Who Use Tobacco | CDC
Caring for Cancer Survivors Who Use Tobacco | CDC (cdc.gov)
Tobacco and Cancer | CDC
Tobacco and Cancer | CDC (cdc.gov)
Health Effects Infographics | CDC
Health Effects Infographics | CDC (cdc.gov)
Cancer and Tobacco Use | Vital Signs - CDC
Cancer and Tobacco Use | Vital Signs - CDC (cdc.gov)
Health Effects of Cigarette Smoking | CDC
Health Effects of Cigarette Smoking | CDC (cdc.gov)
Surveillance for Cancers Associated with Tobacco Use - United States, 2010-2014 | MMWR
Surveillance for Cancers Associated with Tobacco Use - United States, 2010-2014 | MMWR (cdc.gov)
Laringectomía: MedlinePlus enciclopedia médica
Laringectomía: MedlinePlus enciclopedia médica (medlineplus.gov)
Chest Injuries | Chest Disorders | MedlinePlus
Chest Injuries | Chest Disorders | MedlinePlus (medlineplus.gov)
Https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea
Https://www.penny-arcade.com/comic/2008/08/01/the-tender-human-trachea (penny-arcade.com)
What are tiny sacs in the lungs? - Kembrel.com
What are tiny sacs in the lungs? - Kembrel.com (kembrel.com)
Surveillance for Cancer Incidence and Mortality - United States, 2011
Surveillance for Cancer Incidence and Mortality - United States, 2011 (cdc.gov)
Preventing Chronic Disease | Estimating Benefits of Past, Current, and Future Reductions in Smoking Rates Using a Comprehensive...
Preventing Chronic Disease | Estimating Benefits of Past, Current, and Future Reductions in Smoking Rates Using a Comprehensive... (cdc.gov)
COVID-19 and Other Underlying Causes of Cancer Deaths - United States, January 2018-July 2022 | MMWR
COVID-19 and Other Underlying Causes of Cancer Deaths - United States, January 2018-July 2022 | MMWR (cdc.gov)
Tracheomalacia Differential Diagnoses
Tracheomalacia Differential Diagnoses (medscape.com)
Coronavirus Disease 2019 (COVID-19) Treatment & Management: Approach Considerations, Medical Care, Prevention
Coronavirus Disease 2019 (COVID-19) Treatment & Management: Approach Considerations, Medical Care, Prevention (medscape.com)
Figure - Influenza Infection in Wild Raccoons - Volume 14, Number 12-December 2008 - Emerging Infectious Diseases journal - CDC
Figure - Influenza Infection in Wild Raccoons - Volume 14, Number 12-December 2008 - Emerging Infectious Diseases journal - CDC (wwwnc.cdc.gov)
Influenza Infection in Wild Raccoons - Volume 14, Number 12-December 2008 - Emerging Infectious Diseases journal - CDC
Influenza Infection in Wild Raccoons - Volume 14, Number 12-December 2008 - Emerging Infectious Diseases journal - CDC (wwwnc.cdc.gov)
Trachea and Thyroid - Revised Guides for Organ Sampling and Trimming in Rats and Mice
Trachea and Thyroid - Revised Guides for Organ Sampling and Trimming in Rats and Mice (niehs.nih.gov)
Lung Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Lung Anatomy: Overview, Gross Anatomy, Microscopic Anatomy (emedicine.medscape.com)
Laryngeal and Tracheal Stents: Background, History of the Procedure, Problem
Laryngeal and Tracheal Stents: Background, History of the Procedure, Problem (emedicine.medscape.com)
Laryngeal and Tracheal Stents: Background, History of the Procedure, Problem
Laryngeal and Tracheal Stents: Background, History of the Procedure, Problem (emedicine.medscape.com)
Rat Embedding Suggestions - Necropsy Support
Rat Embedding Suggestions - Necropsy Support (niehs.nih.gov)
Trachea Anatomy: Overview, Development of the Human Trachea, Gross Anatomy
Trachea Anatomy: Overview, Development of the Human Trachea, Gross Anatomy (emedicine.medscape.com)
Local Anesthesia of the Airway Technique: Approach Considerations, Blocking the Nasal Cavity, Blocking the Mouth and Oropharynx
Local Anesthesia of the Airway Technique: Approach Considerations, Blocking the Nasal Cavity, Blocking the Mouth and Oropharynx (emedicine.medscape.com)
Congenital Malformations of the Trachea: Overview, Tracheal Agenesis and Atresia, Tracheal Webs and Stenosis (Fibrous...
Congenital Malformations of the Trachea: Overview, Tracheal Agenesis and Atresia, Tracheal Webs and Stenosis (Fibrous... (emedicine.medscape.com)
Congenital Malformations of the Trachea: Overview, Tracheal Agenesis and Atresia, Tracheal Webs and Stenosis (Fibrous...
Congenital Malformations of the Trachea: Overview, Tracheal Agenesis and Atresia, Tracheal Webs and Stenosis (Fibrous... (emedicine.medscape.com)
(emedicine.medscape.com)
Stevens-Johnson Syndrome Clinical Presentation: History, Physical Examination, Complications
Stevens-Johnson Syndrome Clinical Presentation: History, Physical Examination, Complications (medscape.com)