Toxoplasmosis congenital. Medical search

The acquired form of infection by Toxoplasma gondii in animals and man.

Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)

Infection caused by the protozoan parasite TOXOPLASMA in which there is extensive connective tissue proliferation, the retina surrounding the lesions remains normal, and the ocular media remain clear. Chorioretinitis may be associated with all forms of toxoplasmosis, but is usually a late sequel of congenital toxoplasmosis. The severe ocular lesions in infants may lead to blindness.

Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)

A genus of protozoa parasitic to birds and mammals. T. gondii is one of the most common infectious pathogenic animal parasites of man.

Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.

Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.

Immunoglobulins produced in a response to PROTOZOAN ANTIGENS.

One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.

Substances that are destructive to protozoans.

A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.

Infections of the lungs with parasites, most commonly by parasitic worms (HELMINTHS).

Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.

EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.

Deoxyribonucleic acid that makes up the genetic material of protozoa.

Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.

Inflammation of the choroid.

The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Diagnostic procedures involving immunoglobulin reactions.

A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.

Suspensions of attenuated or killed protozoa administered for the prevention or treatment of infectious protozoan disease.

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.

An infant during the first month after birth.

One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

Proteins found in any species of protozoan.

The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic.

The study of parasites and PARASITIC DISEASES.

Disease having a short and relatively severe course.

Inflammation of the choroid as well as the retina and vitreous body. Some form of visual disturbance is usually present. The most important characteristics of posterior uveitis are vitreous opacities, choroiditis, and chorioretinitis.

Inflammation of the lymph nodes.

Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals.

The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.

The transmission of infectious disease or pathogens from one generation to another. It includes transmission in utero or intrapartum by exposure to blood and secretions, and postpartum exposure via breastfeeding.

Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.

Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.

Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.

Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.

Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.

The presence of parasites in food and food products. For the presence of bacteria, viruses, and fungi in food, FOOD MICROBIOLOGY is available.

Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)

An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.

Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.

Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.

A republic in the north of South America, bordered on the west by GUYANA (British Guiana) and on the east by FRENCH GUIANA. Its capital is Paramaribo. It was formerly called Netherlands Guiana or Dutch Guiana or Surinam. Suriname was first settled by the English in 1651 but was ceded to the Dutch by treaty in 1667. It became an autonomous territory under the Dutch crown in 1954 and gained independence in 1975. The country was named for the Surinam River but the meaning of that name is uncertain. (From Webster's New Geographical Dictionary, 1988, p1167 & Room, Brewer's Dictionary of Names, 1992, p526)

The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen.

Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Zygote-containing cysts of sporozoan protozoa. Further development in an oocyst produces small individual infective organisms called SPOROZOITES. Then, depending on the genus, the entire oocyst is called a sporocyst or the oocyst contains multiple sporocysts encapsulating the sporozoites.

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*15 allele family.

A mammalian fetus expelled by INDUCED ABORTION or SPONTANEOUS ABORTION.

A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).

Member of the genus Trichechus inhabiting the coast and coastal rivers of the southeastern United States as well as the West Indies and the adjacent mainland from Vera Cruz, Mexico to northern South America. (From Scott, Concise Encyclopedia Biology, 1996)

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)

An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.

The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319)

Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (From Stedman, 26th ed)

A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.

Measure of the number of the PARASITES present in a host organism.

A phylum of unicellular parasitic EUKARYOTES characterized by the presence of complex apical organelles generally consisting of a conoid that aids in penetrating host cells, rhoptries that possibly secrete a proteolytic enzyme, and subpellicular microtubules that may be related to motility.

The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.

Premature expulsion of the FETUS in animals.

Infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. The central nervous system may be the primary or secondary site of protozoal infection. These diseases may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts.

Diseases affecting the eye.

Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis).

Animals which have become adapted through breeding in captivity to a life intimately associated with humans. They include animals domesticated by humans to live and breed in a tame condition on farms or ranches for economic reasons, including LIVESTOCK (specifically CATTLE; SHEEP; HORSES; etc.), POULTRY; and those raised or kept for pleasure and companionship, e.g., PETS; or specifically DOGS; CATS; etc.

Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.

Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.

Infections with unicellular organisms formerly members of the subkingdom Protozoa.

Fetal cataract in congenital toxoplasmosis. (1/204)

We report a case of the prenatal diagnosis of fetal cataract due to congenital toxoplasmosis. To the best of our knowledge, this is the first report of such a case. We discuss the long-term ocular sequelae of the condition and how they should affect prenatal counselling. (+info)

Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy. (2/204)

OBJECTIVE: To summarise the evidence that treating toxoplasmosis in pregnancy reduces the risk of congenital toxoplasma infection and improves infant outcomes. DESIGN: Systematic review of studies comparing at least two concurrent groups of pregnant women with proved or likely acute toxoplasma infection in which treatments were compared with no treatment and outcomes in the children were reported. SUBJECTS: Studies were identified from Medline (1966-97), Pascal (1990-7), Embase (1993-7), and Biological abstracts (1993-5) plus contact with experts in the field, including the European Research Network on Congenital Toxoplasmosis. MAIN OUTCOME MEASURE: Proportion of infected children at 1 year born to infected pregnant women who were or were not treated. RESULTS: Out of 2591 papers identified, nine met the inclusion criteria. There were no randomised comparisons, and control groups were generally not directly comparable with the treatment groups. Congenital infection was common in treated groups. five studies showed that treatment was effective and four that it was not. CONCLUSION: It is unclear whether antenatal treatment in women with presumed toxoplasmosis reduces congenital transmission of Toxoplasma gondii. Screening is expensive, so the effects of treatment and impact of screening programmes need to be evaluated. In countries where screening or treatment is not routine, these technologies should not be introduced outside carefully controlled trials. (+info)

The ocular manifestations of congenital infection: a study of the early effect and long-term outcome of maternally transmitted rubella and toxoplasmosis. (3/204)

PURPOSE: To study the spectrum of adverse ocular effects which result from maternally transmitted rubella and toxoplasma infection; further, to record the long-term visual and neurodevelopmental outcomes of these 2 major causes of fetal infection. STUDY DESIGN AND PATIENTS: A series of 55 patients with congenital infection have been studied prospectively on a long-term basis. The study group included a cohort of 34 cases with congenital rubella syndrome demonstrated by virus isolation, and 21 cases with a clinical diagnosis of congenital toxoplasmosis and serologic confirmation. All patients had specific disease-related ocular defects. Rubella patients were first identified during or following the last major rubella epidemic in 1963-1964, and some have been followed serially since that time. A separate study group of representative toxoplasmosis patients presented for examination and diagnosis at varying time periods between 1967 and 1991. OBSERVATIONS AND RESULTS: This study confirms that a broad spectrum of fetal injury may result from intrauterine infection and that both persistent and delayed-onset effects may continue or occur as late as 30 years after original infection. Many factors contribute to the varied outcome of prenatal infection, the 2 most important being the presence of maternal immunity during early gestation and the stage of gestation during which fetal exposure occurs in a nonimmune mother. RUBELLA: As a criteria of inclusion, all 34 rubella patients in this study exhibited one or more ocular defects at the time of birth or in the immediate neonatal period. Cataracts were present in 29 (85%) of the 34, of which 21 (63%) were bilateral. Microphthalmia, the next most frequent defect, was present in 28 (82%) of the 34 infants and was bilateral in 22 (65%). Glaucoma was recorded in 11 cases (29%) and presented either as a transient occurrence with early cloudy cornea in microphthalmic eyes (4 patients), as the infantile type with progressive buphthalmos (1 patient), or as a later-onset, aphakic glaucoma many months or years following cataract aspiration in 11 eyes of 6 patients. Rubella retinopathy was present in the majority of patients, although an accurate estimate of its incidence or laterality was not possible because of the frequency of cataracts and nystagmus and the difficulty in obtaining adequate fundus examination. TOXOPLASMOSIS: Twenty-one patients with congenital toxoplasmosis have been examined and followed for varying time periods, 7 for 20 years or more. The major reason for initial examination was parental awareness of an ocular deviation. Twelve children (57%) presented between the ages of 3 months and 4 years with an initial diagnosis of strabismus, 9 of whom had minor complaints or were diagnosed as part of routine examinations. All cases in this study have had evidence of retinochoroiditis, the primary ocular pathology of congenital toxoplasmosis. Two patients had chronic and recurrent inflammation with progressive vitreal traction bands, retinal detachments, and bilateral blindness. Macular lesions were always associated with central vision loss; however, over a period of years visual acuity gradually improved in several patients. Individuals with more severe ocular involvement were also afflicted with the most extensive central nervous system deficits, which occurred following exposure during the earliest weeks of gestation. CONCLUSIONS: Although congenital infection due to rubella virus has been almost completely eradicated in the United States, the long-term survivors from the prevaccination period continue to experience major complications from their early ocular and cerebral defects. They may be afflicted by the persistence of virus in their affected organs and the development of late manifestations of their congenital infection. Congenital toxoplasmosis continues to be the source of major defects for 3,000 to 4,100 infants in the United States each year; the spectrum of defects is wide and may vary from blindness and severe mental retardation to minor retinochoroidal lesions of little consequence. Effective solutions for either the prevention or treatment of congenital toxoplasmosis have not been developed in this country but are under intensive and continuing investigation. (+info)

Value of prenatal diagnosis and early postnatal diagnosis of congenital toxoplasmosis: retrospective study of 110 cases. (4/204)

We reviewed the files of 110 women with Toxoplasma seroconversion during pregnancy. Prenatal diagnosis was attempted for 94 women by amniotic fluid sampling. Toxoplasma gondii was detected by PCR, with or without tissue culture and mouse inoculation. The early neonatal diagnostic procedure included placental testing by PCR and/or mouse inoculation, cord blood serological testing, and comparison of maternal and newborn antibodies by Western blotting (WB). Serological follow-up of the infants was conducted during the first year of life or until the diagnosis of congenital toxoplasmosis (CT) could be ruled out. Congenital infection was diagnosed in 27 individuals (20 live births) in the prenatal and/or neonatal period. The sensitivity and specificity of prenatal diagnosis were 81 and 100%, respectively. Placental examination was positive for 66.7% of individuals with CT and was always negative for neonates without CT. Cord blood serology detected immunoglobulin M (IgM) and/or IgA in 80% of infected newborns, with respective specificities of 91.2 and 87.7%. By WB we detected bands on IgG and IgM blots recognized by the newborn serum but not by the maternal serum (neosynthesized IgG and/or IgM) for 88.2% of infected infants within the first 2 months of life with a specificity of 100%. Early postnatal diagnosis was negative for 2 of the 20 neonates with CT. Both of these newborns had a negative prenatal diagnosis and were asymptomatic, suggesting a very low parasite load. In conclusion, despite the use of advanced methods, some cases of congenital toxoplasmosis cannot be detected early, which underlines the importance of careful follow-up of newborns who are at risk. (+info)

A switch towards Th2 during serological rebound in children with congenital toxoplasmosis. (5/204)

Serological rebounds occur frequently in patients with congenital toxoplasmosis, but remain poorly understood. A link between Th1 and Th2 cytokines and the pathophysiology of infectious diseases has been reported. Production of interferon-gamma (IFN-gamma) and IL-4 in supernatants of whole blood after in vitro specific Toxoplasma gondii stimulation and serum-specific IgE levels were studied in 31 congenitally infected children. IFN-gamma was produced at higher levels by lymphocytes from children with stable congenital toxoplasmosis (n = 18) than from children showing serological rebound (n = 13) (P < 0.04). Conversely, supernatants from children with serological rebound showed higher levels of IL-4 than those from children with stable congenital toxoplasmosis (P < 0.03). The polarized Th2 response was confirmed by a greater (IL-4:IFN-gamma) x 100 ratio (P < 0.0001) and production of T. gondii-specific IgE in six out of 13 children showing serological rebound. These results suggest a role of Th2 cytokines in destabilization of congenital toxoplasmosis and perhaps in local reactivation of the parasite. (+info)

Detection of specific immunoglobulin E during maternal, fetal, and congenital toxoplasmosis. (6/204)

Toxoplasma immunoglobulin E (IgE) antibodies in 664 serum samples were evaluated by using an immunocapture method with a suspension of tachyzoites prepared in the laboratory in order to evaluate its usefulness in the diagnosis of acute Toxoplasma gondii infection during pregnancy, congenital infection, and progressive toxoplasmosis. IgE antibodies were never detected in sera from seronegative women, from patients with chronic toxoplasma infection, or from infants without congenital toxoplasmosis. In contrast, they were detected in 86.6% of patients with toxoplasmic seroconversion, and compared with IgA and IgM, the short kinetics of IgE was useful to date the infection precisely. For the diagnosis of congenital toxoplasmosis, specific IgE detected was less frequently than IgM or IgA (25 versus 67.3%), but its detection during follow-up of children may be interesting, reflecting an immunological rebound. Finally, IgE was detected early and persisted longer in progressive toxoplasmosis with cervical adenopathies, so it was also a good marker of the evolution of toxoplasma infection. (+info)

Experimental toxoplasmosis in Balb/c mice. Prevention of vertical disease transmission by treatment and reproductive failure in chronic infection. (7/204)

In a study of congenital transmission during acute infection of Toxoplasma gondii, 23 pregnant Balb/c mice were inoculated orally with two cysts each of the P strain. Eight mice were inoculated 6-11 days after becoming pregnant (Group 1). Eight mice inoculated on the 10th-15th day of pregnancy (Group 2) were treated with 100 mg/kg/day of minocycline 48 h after inoculation. Seven mice inoculated on the 10th-15th day of pregnancy were not treated and served as a control (Group 3). Congenital transmission was evaluated through direct examination of the brains of the pups or by bioassay and serologic tests. Congenital transmission was observed in 20 (60.6%) of the 33 pups of Group 1, in one (3.6%) of the 28 pups of Group 2, and in 13 (54.2%) of the 24 pups of Group 3. Forty-nine Balb/c mice were examined in the study of congenital transmission of T. gondii during chronic infection. The females showed reproductive problems during this phase of infection. It was observed accentuated hypertrophy of the endometrium and myometrium. Only two of the females gave birth. Our results demonstrate that Balb/c mice with acute toxoplasmosis can be used as a model for studies of congenital T. gondii infection. Our observations indicate the potential of this model for testing new chemotherapeutic agents against congenital toxoplasmosis. (+info)

Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens. (8/204)

Many persons infected with Toxoplasma gondii develop ocular lesions. Immunologic parameters in the response to T. gondii were evaluated in infected persons with and without ocular lesions and in noninfected controls. Subjects were divided into groups on the basis of presence of serum antibodies to T. gondii, presence of ocular lesions, and clinical history. Production of interleukin-2 and interferon-gamma by peripheral blood mononuclear cells from patients with probable congenital toxoplasmosis was decreased, compared with that in persons with presumed acquired infection. Cell proliferation and delayed-type skin reaction induced by soluble toxoplasma tachyzoite antigen followed the same pattern. Asymptomatic persons showed high levels of interleukin-12 and interferon-gamma, whereas persons with ocular lesions had high interleukin-1 and tumor necrosis factor-alpha responses toward soluble toxoplasma tachyzoite antigen. These data suggest that patients with ocular disease due to congenital infection show tolerance toward the parasite. Furthermore, susceptibility to ocular lesions after acquired toxoplasmosis is associated with high levels of interleukin-1 and tumor necrosis factor-alpha, whereas resistance is associated with high levels of interleukin-12 and interferon-gamma. (+info)

Congenital toxoplasmosis is a specific form of toxoplasmosis in which an unborn fetus is infected via the placenta. Congenital ... "Congenital toxoplasmosis". American Family Physician. 67 (10): 2131-8. PMID 12776962. "Congenital toxoplasmosis: MedlinePlus ... Toxoplasmosis Study Group) (15 May 2006). "Outcome of Treatment for Congenital Toxoplasmosis, 1981-2004: The National ... a condition known as congenital toxoplasmosis may affect the child. Toxoplasmosis is usually spread by eating poorly cooked ...

https://en.wikipedia.org/wiki/Toxoplasmosis

Martin S (June 2001). "Congenital toxoplasmosis". Neonatal Network. 20 (4): 23-30. doi:10.1891/0730-0832.20.4.23. PMID 12143899 ... Amniocentesis can be used to detect other congenital infections such as cytomegalovirus, hepatitis B, parvovirus B19, and ... Tissues obtained from amniotic cell lines show significant promise for patients with congenital diseases/malformations of the ... Attwood LO, Holmes NE, Hui L (December 2020). "Identification and management of congenital parvovirus B19 infection". Prenatal ...

https://en.wikipedia.org/wiki/Amniocentesis

Bobić, B; Villena, I; Stillwaggon, E (September 2019). "Prevention and mitigation of congenital toxoplasmosis. Economic costs ... and commonly toxoplasmosis. Toxoplasmosis can be acquired through eating infected undercooked meat or contaminated food, and by ... Instead, toxic exposure often causes physiological abnormalities or minor congenital malformation. Development continues ...

https://en.wikipedia.org/wiki/Prenatal_development

Others include toxoplasmosis, rubella, herpes simplex, and syphilis. For infants who are infected by their mothers before birth ... Congenital CMV cannot be diagnosed if the infant is tested more than one week after birth.[citation needed] Visually healthy ... Congenital HCMV infection occurs when the mother has a primary infection (or reactivation) during pregnancy. Due to the lower ... Antibody tests cannot be used to diagnose congenital CMV; a diagnosis can only be made if the virus is detected during the ...

https://en.wikipedia.org/wiki/Congenital_cytomegalovirus_infection

She has a vision impairment called congenital toxoplasmosis. As a result of the condition, she only has peripheral vision since ...

https://en.wikipedia.org/wiki/María_Delgado

Others are: Toxoplasmosis, Rubella, and Herpes simplex.) Congenital HCMV infection occurs when the mother has a primary ... Congenital cytomegalovirus infection can lead to significant morbidity and even death. After infection, HCMV remains latent ... Congenital HCMV is the leading infectious cause of deafness, learning disabilities, and intellectual disability in children. ... In one case also congenital CMV was encountered. In 2013, Astellas Pharma started on individuals who received a hematopoietic ...

https://en.wikipedia.org/wiki/Human_betaherpesvirus_5

In congenital toxoplasmosis, the disease is bilateral in 65-85% of cases and involves the macula in 58%. Chronic or recurrent ... IgA : Measurement of IgA antibody titers may also be useful in a diagnosis of congenital toxoplasmosis in a fetus or newborn ... Congenital toxoplasmosis may lead to hydrocephalus, seizures, lymphadenopathy, hepatosplenomegaly, rash, and fever. However, ... Congenital disease occurs due to the acquisition of the organism by a pregnant woman exposed to tissue cysts or oocytes in ...

https://en.wikipedia.org/wiki/Toxoplasmic_chorioretinitis

There was no evidence of maternal transmission of antibodies or congenital toxoplasmosis. None of the infected macaques died ...

https://en.wikipedia.org/wiki/Toque_macaque

The illness admitted by Hanley was congenital cerebral toxoplasmosis, described as an "eye disorder"; he was blind in one eye ... Toxoplasmosis is very rarely fatal in adults who do not have a weakened immune system. In 2000, Hanley's friend and colleague ...

https://en.wikipedia.org/wiki/Vincent_Hanley

... global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis". International ... "Toxoplasmosis-a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries". PLOS ... Toxoplasmosis is becoming a global health hazard as it infects 30-50% of the world human population. Clinically, the life-long ... The seroprevalence of toxoplasmosis correlated with various disease burden. Statistical associations does not necessarily mean ...

https://en.wikipedia.org/wiki/List_of_parasites_of_humans

Congenital toxoplasmosis, CMV or rubella may be seen on X-ray as calcifications in the brain. Dense scars may undergo hyaline ...

https://en.wikipedia.org/wiki/Dystrophic_calcification

Idiopathic List of congenital disorders List of ICD-9 codes 740-759: Congenital anomalies Malformative syndrome March of Dimes ... Mother exposure to toxoplasmosis can cause cerebral calcification, hydrocephalus (causes mental disabilities), and intellectual ... Birth defect is a widely used term for a congenital malformation, i.e. a congenital, physical anomaly that is recognizable at ... congenital aplasia or hypoplasia, amniotic band syndrome, and cleidocranial dysostosis. Congenital heart defects include patent ...

https://en.wikipedia.org/wiki/Birth_defect

Due to the risk of congenital toxoplasmosis in the fetus, pregnant women are advised not to eat raw meat. Latent toxoplasmosis ... Congenital toxoplasmosis-further thought for food". BMJ. 321 (7254): 142-147. doi:10.1136/bmj.321.7254.142. PMC 27431. PMID ... Latent toxoplasmosis in adults has been supposed to cause, but not proven to cause, psychological effects and lower IQ in some ... Retrieved 2011-11-15.{{cite web}}: CS1 maint: archived copy as title (link) "Toxoplasmosis , ANSES - Agence nationale de ...

https://en.wikipedia.org/wiki/Steak_tartare

... human congenital toxoplasmosis. Fetus bearer of these alleles thus suffer an increased susceptibility to this disease. GRCh38: ... "ALOX12 in human toxoplasmosis". Infection and Immunity. 82 (7): 2670-9. doi:10.1128/IAI.01505-13. PMC 4097613. PMID 24686056. ...

https://en.wikipedia.org/wiki/ALOX12

Congenital rubella syndrome, Cytomegalovirus, and toxoplasmosis are known to cause deafness or more severe complications in ... Congenital disorders are defined as a set of conditions present at or before birth and can be caused by genetic make up ... Deafblindness is a condition that can be either congenital or acquired. 87% of deafblind children and youth have at least one ... "Congenital disorder - Deformities". Encyclopedia Britannica. Archived from the original on 2015-09-05. CDC (2020-12-30). "Data ...

https://en.wikipedia.org/wiki/Deaf_plus

Congenital toxoplasmosis via transplacental transmission can also lead to sequelae such as chorioretinitis along with ... Chorioretinitis is often caused by toxoplasmosis and cytomegalovirus infections (mostly seen in immunodeficient subjects such ...

https://en.wikipedia.org/wiki/Chorioretinitis

Babies with chromosomal abnormalities or other congenital anomalies may manifest IUGR as part of their syndrome. Problems with ... Infections during pregnancy that affect the fetus, such as rubella, cytomegalovirus, toxoplasmosis, and syphilis, may also ...

https://en.wikipedia.org/wiki/Low_birth_weight

4: Toxoplasmosis and Babesiosis in Asia; Edit-in-chief: Yano A; Vol Edit: Yano A, Nam H-W, Anuar A K, Shen J, Saito A & ... Congenital Infection. In: Current Trends in Pediatrics. Vol. 3; Edit: Mathur GP & Mathur S. Academa Publishers, Delhi, India ...

https://en.wikipedia.org/wiki/Shiba_Kumar_Rai

Congenital leukemia: pediatric cancer due to malignancy of white blood cells. Congenital rhabdomyosarcoma: pediatric cancer due ... Toxoplasmosis: TORCH infection due to Toxoplasma gondii parasite. Condition is commonly associated with undercooked meat or ... The term was coined in the 1960s to describe the skin changes in babies with congenital rubella. Since then, it has been ... Congenital syphilis can present with saber shins, saddle-shaped nose, Hutchinson's teeth, and deafness. Epstein Barr virus: ...

https://en.wikipedia.org/wiki/Blueberry_muffin_baby

The term congenital infection can be used if the vertically transmitted infection persists after childbirth.[citation needed] ... Several vertically transmitted infections are included in the TORCH complex: T - toxoplasmosis from Toxoplasma gondii O - other ... Ford-Jones, E. L.; Kellner, J. D. (1995). ""Cheap torches": An acronym for congenital and perinatal infections". The Pediatric ... The acronym has also been listed as TORCHES, for TOxoplasmosis, Rubella, Cytomegalovirus, HErpes simplex, and Syphilis.[ ...

https://en.wikipedia.org/wiki/Vertically_transmitted_infection

Protozoa like Plasmodium or Toxoplasma which can cause congenital toxoplasmosis with multiple cysts in the brain and other ... congenital rubella syndrome), Zika virus, or bacteria like Treponema pallidum in congenital syphilis, which may progress to ... Common causes of congenital injury are asphyxia (obstruction of the trachea), hypoxia (lack of oxygen to the brain), and the ... see also congenital iodine deficiency syndrome). Excesses in both maternal and infant diets may cause disorders as well, with ...

https://en.wikipedia.org/wiki/Neurodevelopmental_disorder

... is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes ...

https://en.wikipedia.org/wiki/TORCH_syndrome

Congenital infections: syphilis, cytomegalovirus, toxoplasmosis, rubella, human immunodeficiency virus (HIV), malaria, ... ISBN 978-0-323-04883-5. OMIM: 256300 Congenital nephrotic syndrome, Finnish type; Congenital nephrotic syndrome 1 at NIH's ... Congenital nephrotic syndrome is a rare kidney disease which manifests in infants during the first 3 months of life, and is ... Congenital nephrotic syndrome can be successfully controlled with early diagnosis and aggressive treatment including albumin ...

https://en.wikipedia.org/wiki/Congenital_nephrotic_syndrome

He was born with congenital toxoplasmosis which resulted in his vision gradually failing until stabilising at the age of 13 ...

https://en.wikipedia.org/wiki/Carlos_Farrenberg

The fetus of a pregnant woman who has Zika fever may die or be born with congenital central nervous system malformations, like ... toxoplasmosis, rubella, cytomegalovirus infection, lymphocytic choriomeningitis virus infection, and herpes simplex virus. Some ... For infants with suspected congenital Zika virus disease, the CDC recommends testing with both serologic and molecular assays ... Testing should be done for any abnormalities encountered as well as for other congenital infections such as syphilis, ...

https://en.wikipedia.org/wiki/Zika_fever

"The genetics of congenital myopathies". Handbook of Clinical Neurology. 148: 549-564. doi:10.1016/B978-0-444-64076-5.00036-3. ... dystrophy Becker's muscular dystrophy Myotubular myopathy Centronuclear myopathy Electromyogram Trichinosis Toxoplasmosis ... "Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction". Nature Reviews Neurology. 14 (3): ...

https://en.wikipedia.org/wiki/Muscle_biopsy

Vertically transmitted infections Congenital cytomegalovirus infection Toxoplasmosis Congenital rubella syndrome Congenital ... "Congenital Disorders of Glycosylation". NORD (National Organization for Rare Disorders). Retrieved 2019-08-01. "Mito Info". ... The spread of Aedes mosquito-borne Zika virus has been implicated in increasing levels of congenital microcephaly by the ... Leviton, A.; Holmes, L. B.; Allred, E. N.; Vargas, J. (2002). "Methodologic issues in epidemiologic studies of congenital ...

https://en.wikipedia.org/wiki/Microcephaly

Toxic conjunctivitis Toxic shock syndrome Toxocariasis Toxopachyoteose diaphysaire tibio peroniere Toxoplasmosis Toxoplasmosis ... congenital Tracheal agenesis Tracheobronchomalacia Tracheobronchomegaly Tracheobronchopathia osteoplastica Tracheoesophageal ... Thrombocytopenia cerebellar hypoplasia short stature Thrombocytopenia chromosome breakage Thrombocytopenia multiple congenital ...

https://en.wikipedia.org/wiki/List_of_diseases_(T)

... toxoplasmosis and cytomegalovirus from infections acquired following birth. In 1973, Ammann led his research team to perform ... in the cord blood of newborn infants born with the congenital rubella syndrome. This was a major step forward in understanding ...

https://en.wikipedia.org/wiki/Arthur_J._Ammann

... and has the potential to cause congenital toxoplasmosis in the fetus, which has many associated birth complications. Testing ... as CMV is the most common congenital infection and is associated with congenital hearing loss, major handicaps, and death in ... "Cytomegalovirus, Parvovirus B19, Varicella Zoster, and Toxoplasmosis in Pregnancy". www.acog.org. Retrieved 2021-01-25. "Table ...

https://en.wikipedia.org/wiki/HIV_and_pregnancy

Congenital v Congenital toxoplasmosis Congenital unilateral pulmonary hypoplasia Congenital vagal hyperreflexivity Congenital ... Congenital s Congenital megacolon Congenital megaloureter Congenital mesoblastic nephroma Congenital microvillous atrophy ... Congenital mitral malformation Congenital mitral stenosis Congenital mixovirus Congenital mumps Congenital muscular dystrophy ... syringomyelia Congenital myopathy Congenital nephrotic syndrome Congenital nonhemolytic jaundice Congenital rubella Congenital ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

Congenital erosive and vesicular dermatosis Congenital hypertrophy of the lateral fold of the hallux Congenital lip pit ( ... Tarantula bite Tick bite Toxoplasmosis Trichinosis Trichomoniasis Tungiasis (bicho de pie, chigoe flea bite, jigger bite, nigua ... congenital constriction bands, pseudoainhum) Aplasia cutis congenita (cutis aplasia, congenital absence of skin, congenital ... congenital auricular fistula, congenital preauricular fistula, preauricular cyst) Rapidly involuting congenital hemangioma ( ...

https://en.wikipedia.org/wiki/List_of_skin_conditions

Specht J, King G, Brown E, Foris C (2002). "The importance of leisure in the lives of persons with congenital physical ... Risk factors include preterm birth, being a twin, certain infections during pregnancy, such as toxoplasmosis or rubella, ... It has shown that persons with mental or physically debilitating congenital disabilities can lead better lives if they have ... Symptoms and diagnosis typically occur by the age of two, although depending on factors like malformations and congenital ...

https://en.wikipedia.org/wiki/Cerebral_palsy

... anus Ocular convergence spasm Ocular histoplasmosis Ocular melanoma Ocular motility disorders Ocular toxoplasmosis Oculo- ... Osteogenesis Imperfecta Osteogenesis imperfecta congenita microcephaly and cataracts Osteogenesis imperfecta congenital joint ...

https://en.wikipedia.org/wiki/List_of_diseases_(O)

2015). "Neutropenia in congenital and adult babesiosis". Am J Clin Pathol. 144 (1): 94-96. doi:10.1309/AJCP2PHH4HBVHZFS. PMID ... Babesia species are in the phylum Apicomplexa, which also has the protozoan parasites that cause malaria, toxoplasmosis, and ... or by congenital transmission (an infected mother to her baby). Ticks transmit the human strain of babesiosis, so it often ...

https://en.wikipedia.org/wiki/Babesiosis

... congenital MeSH C01.252.400.840.744.800 - syphilis, cutaneous MeSH C01.252.400.840.744.871 - syphilis, latent MeSH C01.252. ... toxoplasmosis, cerebral MeSH C01.539.830.025.325 - epidural abscess MeSH C01.539.830.025.490 - lung abscess MeSH C01.539. ... congenital MeSH C01.252.847.840.744.800 - syphilis, cutaneous MeSH C01.252.847.840.744.871 - syphilis, latent MeSH C01.252. ... Tuberculosis MeSH C01.207.090 Brain Abscess MeSH C01.207.090.800 Toxoplasmosis, Cerebral MeSH C01.252.100.375 - hemorrhagic ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C01)

Congenital hydrocephalus is present in the infant prior to birth, meaning the fetus developed hydrocephalus in utero during ... This condition is acquired as a consequence of CNS infections, meningitis, brain tumors, head trauma, toxoplasmosis, or ... Other causes of congenital hydrocephalus include neural-tube defects, arachnoid cysts, Dandy-Walker syndrome, and Arnold-Chiari ... The most common cause of congenital hydrocephalus is aqueductal stenosis, which occurs when the narrow passage between the ...

https://en.wikipedia.org/wiki/Hydrocephalus

Basson MA, Wingate RJ (September 2013). "Congenital hypoplasia of the cerebellum: developmental causes and behavioral ... toxoplasmosis) rickettsial infection (most are spread through ticks, mites, fleas, or lice) Traumatic brain injury Viral ... ". "Congenital and Inherited Cerebellar Disorders - Nervous System". Merck Veterinary Manual. Retrieved 2019-02-20. "Neural - ... Congenital disorders of nervous system, Neurological disorders). ...

https://en.wikipedia.org/wiki/Cerebellar_hypoplasia_(non-human)

In-utero infections such as rubella, cytomegalovirus, syphilis, toxoplasmosis and herpes. Craniofacial anomalies. Birth weight ... and intervention of congenital and early onset hearing loss. Furthermore, research has shown the importance of early ... A critical review of the role of neonatal hearing screening in the detection of congenital hearing impairment. Health ...

https://en.wikipedia.org/wiki/Audiology_and_hearing_health_professionals_in_developed_and_developing_countries

TRP-004 for toxoplasmosis, TRP-005 for epileptic encephalopathy, and TRP-011 for congenital metabolic disorder. "Leadership ... Daraprim is the trade name for the drug pyrimethamine, which is indicated for the treatment of toxoplasmosis in combination ... At the time of the Daraprim acquisition Turing Pharmaceuticals indicated that it intended to develop new toxoplasmosis drug ... The company has two marketed products: Daraprim (pyrimethamine), for the treatment of toxoplasmosis, and Vecamyl (mecamylamine ...

https://en.wikipedia.org/wiki/Vyera_Pharmaceuticals

... syndrome A result of prematurity Causes from illness/infection Rubella AIDS Cytomegalovirus Congenital syphilis Toxoplasmosis ... The two overarching types of deafblindness are congenital and acquired.: 36-74 Congenital deafblindness: the condition of ... CHARGE syndrome Down syndrome Marshall syndrome Congenital rubella syndrome Stickler syndrome Trisomy 13 Acquired deafblindness ...

https://en.wikipedia.org/wiki/Deafblindness

This was the first published recognition of congenital rubella syndrome (CRS). The progeny had congenital eye, heart and ear ... Cytomegalovirus Rubella Herpes simplex virus HIV Syphilis Toxoplasmosis Varicella zoster virus Venezuelan equine encephalitis ... The time of exposure to the virus also had a direct impact on the incidence of congenital malformations with exposure during ... This term has widely replaced the early term for the study of primarily structural congenital abnormalities, teratology, to ...

https://en.wikipedia.org/wiki/Developmental_toxicity

Ingesting food that has been contaminated with listeriosis, toxoplasmosis, and salmonella is associated with an increased risk ... Anatomical differences are common and can be congenital.[citation needed] In some women, cervical incompetence or cervical ... "Reproductive outcomes in women with congenital uterine anomalies: a systematic review". Ultrasound in Obstetrics & Gynecology. ...

https://en.wikipedia.org/wiki/Miscarriage

... such as toxoplasmosis and American trypanosomiasis (Chagas disease) chronic intracellular bacterial infections such as ... brucellosis chronic lymphocytic leukemia acute lymphoblastic leukemia lymphoma post-splenectomy state CARD11-related congenital ...

https://en.wikipedia.org/wiki/Lymphocytosis

Prenatal causes of intellectual disability include: Congenital infections such as cytomegalovirus, toxoplasmosis, herpes, ...

https://en.wikipedia.org/wiki/Mental_disorders_diagnosed_in_childhood

Congenital toxoplasmosis. BMJ 1992;305:291-7.. * Desmonts G, Courvreur J. Congenital toxoplasmosis: a prospective study of 378 ... European Research Network on Congenital Toxoplasmosis The European Research Network on Congenital Toxoplasmosis was established ... Participants in the National Workshop on Toxoplasmosis: Preventing Congenital Toxoplasmosis Professor Horst Aspöck. Department ... National Workshop on Toxoplasmosis: Preventing Congenital Toxoplasmosis -- meeting summary. Atlanta, GA: US Department of ...

https://www.cdc.gov/mmwr/preview/mmwrhtml/rr4902a5.htm

Congenital toxoplasmosis is a group of symptoms that occur when an unborn baby (fetus) is infected with the parasite Toxoplasma ... Congenital toxoplasmosis is a group of symptoms that occur when an unborn baby (fetus) is infected with the parasite Toxoplasma ... Treatment of infants with congenital toxoplasmosis most often includes pyrimethamine, sulfadiazine, and leucovorin for one year ... For example, toxoplasmosis infection can be passed from cats if you clean the cats litter box.) Call your provider if you are ...

https://medlineplus.gov/ency/article/001360.htm

JavaScript is disabled for your browser. Some features of this site may not work without it ...

https://extranet.who.int/iris/restricted/browse?authority=Toxoplasmosis%2C+Congenital&type=mesh

Freeman K, Oakley L, Pollak A, Buffolano W, Petersen E, Semprini AE, Association between congenital toxoplasmosis and preterm ... toxoplasmosis), 771.2a (a special KPNC subset code specifying toxoplasmosis), and those with the more general 771.2 (congenital ... Rate of Congenital Toxoplasmosis in Large Integrated Health Care Setting, California, USA, 1998-2012 On This Page ... Rate of Congenital Toxoplasmosis in Large Integrated Health Care Setting, California, USA, 1998-2012. Emerging Infectious ...

https://wwwnc.cdc.gov/eid/article/20/9/13-1919_article

Cases of congenital toxoplasmosis with severe jaundice early after birth combined with pancytopenia and splenomegaly are ... Infants with congenital toxoplasmosis require long-term follow-up, focusing on nervous system development and ophthalmology. ... Here, we report on a rare case of congenital toxoplasmosis presenting with severe jaundice and hemolysis early after birth ... In this case of congenital toxoplasmosis combined with severe jaundice, we treated the infant with two courses of azithromycin ...

https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06619-1

Toxoplasmosis is caused by infection with the protozoan Toxoplasma gondii, an obligate intracellular parasite. The infection ... Congenital toxoplasmosis usually is a subclinical infection. Among immunodeficient individuals, toxoplasmosis most often occurs ... Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to ... Congenital toxoplasmosis. Approximately 10-20% of pregnant women infected with T gondii become symptomatic. [18] The most ...

https://www.medscape.com/answers/229969-41287/what-is-the-frequency-of-symptoms-in-acute-toxoplasmosis

IMSEAR is the collaborative product of Health Literature, Library and Information Services (HELLIS) Network Member Libraries in the WHO South-East Asia Region ...

https://imsear.searo.who.int/handle/123456789/14183

Toxoplasmosis is caused by infection with the protozoan Toxoplasma gondii, an obligate intracellular parasite. The infection ... Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to ... Prenatal education for congenital toxoplasmosis. Cochrane Database Syst Rev. 2013 Feb 28. 2:CD006171. [QxMD MEDLINE Link]. ... Salviz M, Montoya JG, Nadol JB, Santos F. Otopathology in Congenital Toxoplasmosis. Otol Neurotol. 2013 Apr 17. [QxMD MEDLINE ...

https://emedicine.medscape.com/article/229969-medication

Use of the polymerase chain reaction in diagnosing congenital toxoplasmosis Unknown author (‎1996)‎ ...

https://apps.who.int/iris/discover?field=subject&filtertype_0=dateIssued&filter_relational_operator_0=equals&filter_0=%5B1960+TO+1999%5D&filtertype=subject&filter_relational_operator=equals&filter=Abortion%2C+Induced

Humans, Pregnancy Complications, Parasitic, Toxoplasmosis, Congenital, Spiramycin, Antiprotozoal Agents, Pregnancy, Infant, ...

https://www.psi.ox.ac.uk/publications/1059643

Toxoplasmosis is caused by infection with the protozoan Toxoplasma gondii, an obligate intracellular parasite. The infection ... Toxoplasmosis is a serious and often life-threatening disease in immunodeficient patients. Congenital toxoplasmosis may ... Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to ... Prenatal education for congenital toxoplasmosis. Cochrane Database Syst Rev. 2013 Feb 28. 2:CD006171. [QxMD MEDLINE Link]. ...

https://emedicine.medscape.com/article/229969-clinical

... presents information about Toxoplasma gondii and its infection in ... Congenital Toxoplasmosis in Humans and Domestic Animals eBook: US $39 Special Offer (PDF + Printed Copy): US $90. Printed Copy ... In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such ... and treatment of both human and veterinary toxoplasmosis. ...

https://benthambooks.com/book/9781681086439/comments/

Miron D, Raz R, Luder A. Congenital toxoplasmosis in Israel: to screen or not to screen. Israel Medical Association journal, ... Résultats et perspectives du dépistage anténatal et du suivi du nouveau-né [Prevention of congenital toxoplasmosis in France. ... Preventing congenital toxoplasmosis. MMWR recommendations and reports, 2000, 49(RR-2):59-68. ... Thulliez P. Screening programme for congenital toxoplasmosis in France. Scandinavian journal of infectious diseases, 1992, 84: ...

https://www.emro.who.int/emhj-volume-15-2009/volume-15-issue-5/seroprevalence-and-associated-risk-factors-of-toxoplasmosis-in-pregnant-women-in-hebron-district-palestine.html

The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4-Gra7 antigens for early congenital toxoplasmosis (CT) ... Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis. ... Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital tox ...

https://pesquisa.bvsalud.org/portal/resource/pt/mdl-34942587

https://wwwnc-origin.cdc.gov/eid/article/20/9/13-1919_article

Screening programme for congenital toxoplasmosis in France.. *P. Thulliez. *. Medicine. Scandinavian journal of infectious ... Impact of Syrian refugees on congenital TORCH infections screening in Turkey. *B. Coşkun, Ç. Gülümser, B. Çoşkun, C. Artuk, K. ... Congenital Infections, Part I: Cytomegalovirus, Toxoplasma, Rubella, and Herpes Simplex. *Cuixia Tian, S. Ali ... It was not appropriate at the present time to introduce a nationwide antenatal screening programme for toxoplasmosis in the UK ...

https://www.semanticscholar.org/paper/TORCH-test-for-fetal-medicine-indications%3A-only-CMV-Abdel-Fattah-Bhat/31f4f793506994fbe2d53927063621b2c96c7a32

Epidemiology of congenital toxoplasmosis identified by population-based newborn screening in Massachusetts. JARA, MICHELE; HSU ...

https://journals.lww.com/pidj/toc/2001/12000

Toxoplasmosis Worldwide; Wide reservoir in Sanitation and hygiene; None -- common infection; rodents, cats, swine, education of ... congenital immunity; relapses and treatment infections severe, fatal, or chronic Toxocariasis (visceral Chronic disease of ... Low congenital) especially urban; diagnosis difficult; treatment, condoms; ,=5% prevalence in serology; sexual education; ...

https://wonder.cdc.gov/wonder/prevguid/m0025967/m0025967.asp

To ensure that those identified with congenital hearing loss receive the genetic services appropriate to their conditions, the ... A significant proportion of those with congenital hearing loss have genetic etiologies underlying their hearing loss. ... Intrauterine infections (e.g., toxoplasmosis, other agents, rubella, CMV, herpes simplex [TORCH]). ... Genetics Evaluation Guidelines for the Etiologic Diagnosis of Congenital Hearing Loss. *Genetic Evaluation of Congenital ...

https://www.nature.com/articles/gim200232?error=cookies_not_supported&code=3ac56b6b-b44e-4001-983d-5be16d4501a9

Congenital toxoplasmosis. The Toxoplasmosis Study Group. Semin Pediatr Neurol 1994;1(1):4-25. ... Long-term outcome of children with congenital toxoplasmosis. Am J Obstet Gynecol 2010;203(6):552.e1-6. Epub 2010 Jul 15.doi: ... Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy. BMJ 1999;318(7197):1511-4. ... Congenital toxoplasmosis. Handb Clin Neurol 2013;112:1099-101.doi:10.1016/B978-0-444-52910-7.00028-3. ...

https://www.cfp.ca/content/60/4/334

According to a 1999 CDC report, toxoplasmosis is the third leading cause of death due to food borne infections and leads to an ... estimated 400 to 6,000 cases of congenital infection in the United States. The accuracy of these estimates, however, is unknown ... Serum tests for both IgG and IgM antibody to toxoplasmosis will be added to the NHANES 2001 laboratory protocol to obtain the ... Evidence from Europe suggests that the incidence of toxoplasmosis has dropped substantially in the last decade; data from the U ...

https://wwwn.cdc.gov/Nchs/Nhanes/1999-2000/LAB17.htm

Congenital toxoplasmosis. *Congenital rubella. *Congenital CMV. *HIV/AIDS. *Weak immune status. *Exposure to pets, raw or ...

https://uvahealth.com/services/eye-care/chorioretinitis

... global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis". International ... Toxoplasmosis (Acute and Latent) Toxoplasma gondii eyes, brain, heart, liver blood and PCR worldwide: one of the most common ... Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries". PLOS ONE. 9 (3): e90203. Bibcode: ... Toxoplasmosis is becoming a global health hazard as it infects 30-50% of the world human population. Clinically, the life-long ...

https://en.wikipedia.org/wiki/List_of_parasites_of_humans

Congenital hip dislocation. *Congenital toxoplasmosis. *Crying, excessive (0-6 months). *Delivery presentations ...

https://www.stlukes-stl.com/health-content/pregnancy/2/2252.htm

Diagnosis, treatment, and prevention of congenital toxoplasmosis in the United States. Maldonado, Y. A., Read, J. S., Byington ...

https://www.scholars.northwestern.edu/en/persons/tina-quanbee-tan/publications/

Congenital Toxoplasmosis: A Neglected Disease? - Current Brazilian public health policy [Full text] ...

https://journals.openedition.org/factsreports/1092

Jones J, Lopez A, & Wilson M. Congenital Toxoplasmosis. American Family Physician. 2003: 67 (10): 2131-2138.. March of Dimes. ... The risk here is toxoplasmosis, which can be transmitted to your fetus if you accidentally come into contact with the T. gondii ... "If youre a cat owner and are really worried about toxoplasmosis, your doctor can test you for the antibodies in your blood," ...

https://www.sharecare.com/womens-health/pregnancy/can-get-hot-tub-while-pregnant

Only seven cases of congenital human toxoplasmosis were confirmed in 2017.. A previous survey by the German Federal Institute ... Tags: BMC Public Health, Campylobacter, consumer survey, Germany, meat, Salmonella, Toxoplasma, toxoplasmosis ... In all age groups, less than 25 percent knew how to protect themselves from toxoplasmosis infection. ...

https://www.foodsafetynews.com/2020/03/survey-finds-low-campylobacter-knowledge-in-germany/

A pilot newborn screening programme for congenital toxoplasmosis in the Republic of Ireland. Mayne P.1, Guy E.2, Finnegan N.1, ... Congenital toxoplasmosis (CT) is caused by toxoplasma infection acquired by susceptible women during pregnancy. Studies ... Methods: The study was performed with the same blood spots specimen dried on filter paper used for Congenital Hypothyroidism, ... Newborn bloodspot screening for Phenylketonuria (PKU), Congenital Hypothyroidism (CHT) and Cystic Fibrosis (CF) is available ...

https://www.prolekare.cz/casopisy/cesko-slovenska-pediatrie/2009-4/abstrakta-pokracovani-4846

The acronym 'TORCH' refers to well‐recognised causes of perinatal infections: toxoplasmosis, rubella, cytomegalovirus (CMV) and herpes simplex virus (HSV). (semanticscholar.org)
We need to conduct studies of active surveillance in the southern US and selected inner cities to better determine the prevalence of illnesses such as toxocariasis, toxoplasmosis, trichomoniasis, congenital cytomegalovirus infection, and hepatitis C. At a minimum we should know as much about these diseases as we do HIV/AIDS. (theweeklychallenger.com)
The most common causes of microcephaly choice of hospital care may be a viable option, especially are genetic and exposure to risk factors, such as: infections by before a greater number of procedures that the patient with syphilis, toxoplasmosis, rubella, cytomegalovirus and herpes microcephaly has and the option of performing them in a simplex virus, severe malnutrition due to lack of nutrients or single appointment care. (bvsalud.org)

In addition, infections in pregnant women can cause serious health problems in the fetus if the parasites are transmitted (i.e., congenital toxoplasmosis) and cause severe sequelae in the infant (e.g., mental retardation, blindness, and epilepsy). (cdc.gov)
Because congenital toxoplasmosis poses a substantial public health problem, CDC has developed prevention recommendations to reduce the risk for congenital infections. (cdc.gov)
An overview of the pathogenesis, epidemiology and clinical consequences of congenital TORCH infections is provided and the indications for, and interpretation of, TORCH screens are discussed. (semanticscholar.org)
Routine TORCH screening in neonates with LSV cases should only be regarded as mandatory once well-designed studies demonstrate a clear diagnostic benefit, and efforts to diagnose congenital infections in cases presenting with LSv have a poor yield. (semanticscholar.org)
The effect of the Syrian refugee population on the prevalence of congenital TORCH infections and the cost‐effectiveness of population‐based TORCH screening during pregnancy in Turkey are demonstrated. (semanticscholar.org)
According to a 1999 CDC report, toxoplasmosis is the third leading cause of death due to food borne infections and leads to an estimated 400 to 6,000 cases of congenital infection in the United States. (cdc.gov)
The increased occurrence of microcephaly associated with cerebral damage characteristically seen in congenital infections in Zika virus-affected areas is suggestive of a possible relationship. (cdc.gov)
Tests for other congenital infections were negative. (cdc.gov)
Indeed the CDC has shown that co-infections with toxoplasmosis and toxocariasis are common. (theweeklychallenger.com)
Like other HIV-associated infections, the seroprevalence and prevalence of CNS toxoplasmosis vary depending on geographical area and demographics. (medscape.com)
The approach to neonatal congenital infections - toxoplasmosis and syphilis. (bvsalud.org)
TORCH test is used to detect these types of torch infections which can lead to illness and congenital abnormalities. (mfine.co)
Previous research has shown that toxoplasmosis toxoplasmosis among humans and animals and is one infection was more common among those with history of the most prevalent chronic infections, infecting one- of close contact with cats, raw meat and vegetable third of the world population ( 1-5 ). (who.int)
Authored by experts in the fields of embryology, microbiology, and epidemiology, the book features 13 state-of-the-art reviews covering morphology, etiology, epidemiology, conventional and newer techniques fr laboratory diagnosis, the cost-effectiveness of routine screening, and the extent to which these infections account for congenital malformations, including mental retardation. (who.int)
Information on viral and bacterial infections is complemented by sections devoted to chlamydiae, toxoplasmosis, and urinary tract infections. (who.int)
While most infections are mild, infection in a pregnant woman may cause devastating foetal malformations and may result in stillbirths, miscarriage or a pattern of birth defects known as congenital rubella syndrome (CRS). (who.int)
Public health jurisdictions are encouraged to evaluate, report, and monitor identified ZIKV infections, particularly in pregnant women, that don't meet the clinical criteria of the confirmed and probable congenital and non-congenital disease case classifications. (cdc.gov)

Like syphilis, congenital toxoplasmosis may cause brain damage and problems with vision and hearing. (justia.com)

Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii . (cdc.gov)
Congenital toxoplasmosis is a group of symptoms that occur when an unborn baby (fetus) is infected with the parasite Toxoplasma gondii . (medlineplus.gov)
Toxoplasmosis (Toxoplasma gondii). (medlineplus.gov)
Congenital transmission can occur when a woman is infected with Toxoplasma gondii during, or just before, pregnancy. (cdc.gov)
12 months of age, PCR-positive results for T. gondii , or diagnosis and care of toxoplasmosis-related conditions. (cdc.gov)
Wolf, Cowan, and Paige (1937-1939) determined that these findings represented the syndrome of severe congenital T gondii infection. (medscape.com)
Among immunodeficient individuals, toxoplasmosis most often occurs in those with defects of T-cell-mediated immunity, such as those with hematologic malignancies, bone marrow and solid organ transplants, or acquired immunodeficiency syndrome ( AIDS ).In most immunocompetent individuals, primary or chronic (latent) T gondii infection is asymptomatic. (medscape.com)
Congenital Toxoplasmosis in Humans and Domestic Animals presents information about Toxoplasma gondii and its infection in neonates and different animals (cats, cattle, dogs, goats, pigs and sheep). (benthambooks.com)
ABSTRACT To measure the prevalence of toxoplasmosis, we tested 204 pregnant women for IgG and IgM antibodies to Toxoplasma gondii using an enzyme-linked immunoassay. (who.int)
Toxoplasmosis is a very common infection caused by the obligate intracellular protozoan parasite Toxoplasma gondii. (who.int)
Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis. (bvsalud.org)
Toxoplasmosis is a disease caused by the intracellular protozoan parasite Toxoplasma gondii . (cfp.ca)
5 Critically, when a T gondii infection is acquired in pregnancy, the parasite can be transmitted across the placenta to the fetus, resulting in congenital toxoplasmosis, which can have grave consequences. (cfp.ca)
Congenital toxoplasmosis is caused by vertical transmission of Toxoplasma gondii from mother during pregnancy. (koreamed.org)
In humans, transmission of Toxoplasma gondii from the mother to the foetus is considered to be most efficient during the last trimester of pregnancy but clinical congenital toxoplasmosis is more severe if the transmission occurs during the first trimester. (usda.gov)
However, there are no data on the rate of congenital transmission of T. gondii with respect to gestational age in any host during natural infection. (usda.gov)
Because T. gondii can cause such severe problems, toxoplasmosis accounts for $3.3 billion to $7.8 billion per year in economic costs. (cspinet.org)
Toxoplasma gondii (T. gondii) is an intracellular parasite liable for inflicting toxoplasmosis. (g2reports.com)
Congenital toxoplasmosis results from a primary infection with Toxoplasma gondii during pregnancy. (mavipuro.pl)
Risk factors for toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: Implications for prenatal management and screening. (mavipuro.pl)
Infección prenatal causada por el protozoo TOXOPLASMA gondii, que se asocia a lesiones del sistema nervioso fetal en desarrollo. (bvsalud.org)
Toxoplasmosis is an infection due to the parasite Toxoplasma gondii. (medifind.com)
T polymorphisms to congenital infection with Toxoplasma gondii. (cdc.gov)
Toxoplasmosis: This is an infectious disease caused by a parasite known as Toxoplasma gondii and passed from an expecting lady, often in the first three months to the fetus through the placenta. (mfine.co)

Mothers with toxoplasmosis must be completely informed of the disease's potential consequences to the fetus. (medscape.com)
In addition, congenital toxoplasmosis, where the parasite is transmitted from the pregnant woman to her fetus, is estimated to cause mental retardation and blindness in as many as 400 to 6,000 children and may kill another 80 fetuses and newborns each year. (cspinet.org)
Thus, the objective of this project is to assess the levels of miRNAs and cytokines in paired samples from mother (serum / plasma of pregnant women with acute toxoplasmosis) and fetus (amniotic fluid) in order to identify potential miRNAs that are markers of congenital infection. (fapesp.br)
Thus, the study of new markers of congenital infection could assist in the development of new diagnostic tools, implying a more aggressive therapy, in the prognosis of infection, in the study of new therapeutic targets and provide a greater understanding of the poorly studied mother-fetus binomial. (fapesp.br)

The symptoms of congenital toxoplasmosis include abnormal changes in head size (hydrocephaly or microcephaly), intracranial calcifications, deafness, seizures, cerebral palsy, damage to the retina, and mental retardation. (cdc.gov)
Design Nine ReLAMC congenital anomaly registries provided case-level data or aggregate data for any live births, still births or terminations of pregnancy with microcephaly. (bmj.com)
Liveborn infant with congenital microcephaly, or intracranial calcifications, or structural brain or eye abnormalities, or other congenital central nervous system-related abnormalities not explained by another etiology. (cdc.gov)

Here, we report on a rare case of congenital toxoplasmosis presenting with severe jaundice and hemolysis early after birth combined with pancytopenia and splenomegaly. (biomedcentral.com)
In this case of congenital toxoplasmosis combined with severe jaundice, we treated the infant with two courses of azithromycin, followed by trimethoprim-sulfamethoxazole after the jaundice resolved. (biomedcentral.com)

The greatest challenge in diagnosing toxoplasmosis is to establish the acute (primary) infection and distinguish it from past (chronic) infection. (cfp.ca)
Some cases of acute toxoplasmosis in adults are associated with psychiatric symptoms such as delusions and hallucinations. (cdc.gov)
Approximately 1 of every 500 pregnant women acquires acute toxoplasmosis, and ap-proximately 10 to 20% of the involved women become symptomatic. (brainkart.com)

Treatment of infants with congenital toxoplasmosis most often includes pyrimethamine, sulfadiazine, and leucovorin for one year. (medlineplus.gov)
Infants with congenital toxoplasmosis require long-term follow-up, focusing on nervous system development and ophthalmology. (biomedcentral.com)

Importance of screening serological examination of umbilical blood and the blood of the mother for timely diagnosis of congenital toxoplasmosis and toxocariasis. (nel.edu)
Veleminsky M, Veleminsky M, Fajfrlik K, Kolarova L. Importance of screening serological examination of umbilical blood and the blood of the mother for timely diagnosis of congenital toxoplasmosis and toxocariasis. (nel.edu)
Richard-Lenoble D. Prenatal diagnosis of congenital toxoplasmosis: the role of Toxoplasma IgA antibodies in amniotic fluid [letter]. (calbiotech.com)
Prenatal diagnosis of congenital toxoplasmosis with a polymerase-chain-reaction test on amniotic fluid. (mavipuro.pl)

Primary prevention based on prenatal education could be an effective strategy to reduce congenital toxoplasmosis. (medscape.com)
Toxoplasmosis is a great public health concern due to its capacity for prenatal transmission. (who.int)

Up to half babies who become infected with toxoplasmosis during the pregnancy are born early (prematurely). (medlineplus.gov)
A mother may not show any symptoms of this infection, but she may transmit toxoplasmosis to her child if she is infected for the first time during pregnancy or shortly before it. (justia.com)
When a pregnant mother acquires toxoplasmosis during pregnancy it can result in a congenital infection that leads to profound mental disabilities, but even when acquired as an older child or adult it can lead to a number of psychiatric and mental illnesses. (theweeklychallenger.com)
When infection happens throughout pregnancy, it might produce extreme congenital infection with ocular and neurologic harm to the toddler. (g2reports.com)
Since recent studies are looking for miRNAs that could be biomarkers of complications associated with pregnancy, little is known in the context of infectious and parasitic diseases, such as congenital toxoplasmosis. (fapesp.br)
A number of serological tests, such as the latex during pregnancy may lead to congenital toxoplasmosis agglutination test, enzyme-linked immunosorbent with neonatal complications ( 6 ). (who.int)

Congenital toxoplasmosis causes neurologic or ocular disease (leading to blindness), as well as cardiac and cerebral anomalies. (cfp.ca)
Congenital rubella syndrome may cause heart defects and problems with vision and hearing, in addition to cerebral palsy. (justia.com)
Our findings on characterization of immune response of patients with symptomatic toxoplasmosis (ocular and cerebral) identified potential miRNAs that could be involved in regulating the production of important cytokines for infection control. (fapesp.br)

Although it is known that humans may acquire toxoplasmosis in a variety of ways, data on their relative frequency are both meager and conflicting. (brainkart.com)
Toxoplasmosis is found in humans worldwide and in many kinds of animals and birds. (medifind.com)

According to a study published in BMJ , congenital Zika virus syndrome is associated with arthrogryposis, a severe joint condition. (contagionlive.com)
Due to the rapidly evolving epidemic of Zika virus infection, the Council of State and Territorial Epidemiologists (CSTE) Executive Board developed an interim position statement to establish standardized case definitions for Zika virus disease and ZIKV congenital infection dated February 26, 2016, and to add these conditions to the Nationally Notifiable Diseases List. (cdc.gov)

Cases of congenital toxoplasmosis with severe jaundice early after birth combined with pancytopenia and splenomegaly are extremely rare. (biomedcentral.com)
[ 3 ] However, certain individuals are at high risk for severe or life-threatening toxoplasmosis . (medscape.com)
Congenital toxoplasmosis may manifest as a mild or severe neonatal disease, with onset during the first month of life or with sequelae or relapse of a previously undiagnosed infection at any time during infancy or later in life. (medscape.com)
Clinical toxoplasmosis is most severe in congenitally-infected hosts. (usda.gov)

The prevalence of congenital toxoplasmosis in China is estimated to be approximately 1.1 per 1000 live births based on the data from toxoplasma-specific IgM tests of pregnant women in China [ 1 ]. (biomedcentral.com)

In addition to causing congenital infection, trophozoites have been responsible for disease transmission in a number of other situations, including laboratory accidents, transfusions of whole blood and leukocytes, and organ transplantation. (brainkart.com)

Ocular toxoplasmosis is one clinical presentation of congenital or acquired infection. (biomedcentral.com)
A study in the State of Rio Grande do Sul revealed a prevalence of ocular toxoplasmosis of 21.3 % in over 13-year-old individuals and concluded that the disease is a consequence of postnatal infection [ 10 ]. (biomedcentral.com)
Their top areas of expertise are Toxoplasmosis, Congenital Toxoplasmosis, Primary Amebic Meningoencephalitis, Ocular Toxoplasmosis, and Bone Marrow Transplant. (medifind.com)

Some sequelae of congenital toxoplasmosis are not apparent at birth and may not become apparent until the second or third decade of life. (cdc.gov)

Readers will have quick access to the pathophysiology, diagnosis, reproductive disorders (such as abortion, neonatal mortality and prematurity) and treatment of both human and veterinary toxoplasmosis. (benthambooks.com)
In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such control programs are discussed. (benthambooks.com)

Serologic tests are available to determine who has become infected with toxoplasmosis. (cdc.gov)
There are several neonates with congenital toxoplasmosis and patients serologic tests for anti-toxoplasma IgM and IgG, among with immunodeficiency status ( 8-9 ). (who.int)

Question Congenital toxoplasmosis is a dangerous fetal infection. (cfp.ca)

Pregnant women and those with HIV/AIDS should be screened for toxoplasmosis. (medifind.com)
The objective of the present study was to determine the seroprevalence of toxoplasmosis in pregnant women. (bvsalud.org)
Serologic studies have reported various estimates for seroprevalence of toxoplasmosis among Iranian pregnant women. (who.int)
Our study showed that a considerable proportion of Iranian pregnant women are at high risk for toxoplasmosis. (who.int)

However, a baby who does acquire rubella from their mother may develop congenital rubella syndrome. (justia.com)
In line with the regional aim of eliminating rubella and congenital rubella syndrome (CRS), phased introduction of rubella-containing vaccines (RCV) in the Philippines' routine immunization programme began in 2010. (who.int)

An estimated 400-4,000 cases of congenital toxoplasmosis occur each year in the United States. (cdc.gov)
Although congenital toxoplasmosis is not a nationally reportable disease and no national data are available regarding its occurrence, extrapolation from regional studies indicates that an estimated 400-4,000 cases occur in the United States each year. (cdc.gov)

Although congenital toxoplasmosis occurs throughout the United States, little information is available about the rates of diagnosed illness in most of the nation, including California. (cdc.gov)
Pulmonary toxoplasmosis occurs mainly in patients with advanced AIDS (mean CD4 + count of 40 cells/µL ±75 standard deviation) and primarily manifests as a prolonged febrile illness with cough and dyspnea. (medscape.com)
Toxoplasmosis is a cosmopolitan disease that occurs in almost all mammals and many birds. (brainkart.com)
Clinical CNS toxoplasmosis occurs in 3%-15% of patients with AIDS in the United States, where 789 toxoplasmosis deaths were identified during an 11-year study period from 2000 to 2010. (medscape.com)
Clinical CNS toxoplasmosis occurs in as many as 50%-75% of patients in some European countries and in Africa. (medscape.com)
Congenital rubella is a condition that occurs in an infant whose mother is infected with the virus that causes German measles. (adam.com)

The seroprevalence of toxoplasmosis in the present study is common. (bvsalud.org)

Only seven cases of congenital human toxoplasmosis were confirmed in 2017. (foodsafetynews.com)

Human Toxoplasmosis: Occurrence in Infants as an Encephalomyelitis Verification of Transmission to Animals" (1939), by Abner Wolf et al. (asu.edu)
They published the results of their experiment in Human Toxoplasmosis: Occurrence in Infants as an Encephalomyelitis Verification of Transmission to Animals. (asu.edu)

The incidence of congenital toxoplasmosis is influenced by maternal infective status, climate, and socioeconomic conditions. (biomedcentral.com)
To ensure that those identified with congenital hearing loss receive the genetic services appropriate to their conditions, the Maternal and Child Health Bureau of the Health Resources and Services Administration funded the American College of Medical Genetics to convene an expert panel to develop guidelines for the genetic evaluation of congential hearing loss. (nature.com)

Parasitic diseases, particularly the congenital form of toxoplasmosis, can negatively affect the mortality and morbidity of newborns and infants. (nel.edu)

A study shows that combination of the immunomodulatory agents, levamisole and Echinacea, and pyrimethamine plus sulfadiazine for the treatment of toxoplasmosis increases the survival of mice. (medscape.com)
Toxoplasmosis as adjunctive therapy with pyrimethamine. (rxlist.com)
Systemic sulfonamides are contraindicated in infants less than 2 months of age, except in the treatment of congenital toxoplasmosis as adjunctive therapy with pyrimethamine. (rxlist.com)

In September 1998, CDC convened the National Workshop on Toxoplasmosis: Preventing Congenital Toxoplasmosis (NWTPCT) in Atlanta, Georgia, to discuss research priorities for preventing the disease. (cdc.gov)
Toxoplasmosis is a serious and often life-threatening disease in immunodeficient patients. (medscape.com)
Congenital Toxoplasmosis: A Neglected Disease? (openedition.org)
Treatment congenital toxoplasmosis in active disease more common problems that may progress to joint destruction ie, hemophilic arthropathy. (aaan.org)
Clinical disease presents in three major forms: (1) self-limiting febrile lymphadenopathy, (2) highly lethal infection of immunocompromised patients, and (3) congenital infection of infants. (brainkart.com)
Toxoplasmosis was recently included as a neglected disease by the Center for Disease Control. (biomedcentral.com)
Toxoplasmosis can affect various organ systems, but in HIV-infected patients it most commonly manifests itself as CNS toxoplasmosis, a leading cause of focal central nervous system (CNS) disease in AIDS. (medscape.com)
CNS toxoplasmosis in HIV-infected patients is usually a complication of the advanced phase of the disease. (medscape.com)

Approximately 70% of congenital cases associated with genetic factors are classified as nonsyndromic (the deafness is not associated with other clinical findings that define a recognized syndrome). (nature.com)
Congenital varicella syndrome can arise from a chickenpox infection transmitted from the mother. (justia.com)
Congenital varicella syndrome also can cause problems with vision and skin. (justia.com)
If a mother received the chickenpox vaccine or had a previous chickenpox infection, she likely will not contract chickenpox, and her baby will not develop congenital varicella syndrome. (justia.com)

Congenital toxoplasmosis has a wide variety of manifestations during the perinatal period. (medscape.com)

Objective The Latin American Network of Congenital Malformations: ReLAMC was established in 2017 to provide accurate congenital anomaly surveillance. (bmj.com)

The samples were examined for the titre of antibodies - the CFR, levels of immunoglobulins IgA and IGM (toxoplasmosis) and for titres of antibodies against toxocariasis. (nel.edu)

Newborn bloodspot screening for Phenylketonuria (PKU), Congenital Hypothyroidism (CHT) and Cystic Fibrosis (CF) is available for all babies born in Scotland. (prolekare.cz)

What are the possible complications of Toxoplasmosis? (medifind.com)

The global incidence of congenital toxoplasmosis is approximately 190,100 cases annually, with an incidence rate of approximately 1.5 per 1000 live births [ 1 ]. (biomedcentral.com)

Timely diagnosis and adequate treatment are closely associated with congenital toxoplasmosis-related prognosis. (biomedcentral.com)
What is the outlook (prognosis) for Toxoplasmosis? (medifind.com)

A related parasitic infection acquired from cat feces is toxoplasmosis, which also disproportionately affects African Americans living in poverty. (theweeklychallenger.com)
Toxoplasmosis is caused mainly by eating uncooked eggs or meat and handling the feces of cats. (mfine.co)

Only 10-20% of toxoplasmosis cases in adults and children are symptomatic. (medscape.com)

Many cases of congenital toxoplasmosis can be prevented. (cdc.gov)
Our goal was to determine the rate of clinically identified cases of congenital toxoplasmosis in children from birth to 2 years of age within the Northern California Kaiser Permanente Medical Care Program (KPNC) during a 15-year period. (cdc.gov)
After electronic and paper charts were reviewed, 2 cases of congenital toxoplasmosis were confirmed. (cdc.gov)
In Europe and the United States, type II genotype is responsible for most cases of congenital toxoplasmosis. (medscape.com)
In some cases, medicine to prevent toxoplasmosis may be given. (medifind.com)

Brain involvement (ie, toxoplasmic encephalitis), with or without focal CNS lesions, is the most common manifestation of toxoplasmosis in individuals with AIDS. (medscape.com)

Symptoms associated with reactivation toxoplasmosis are dependent on the tissue or organ affected. (medscape.com)
CNS toxoplasmosis begins with encephalitis and constitutional symptoms and headache. (medscape.com)
What are the symptoms of Toxoplasmosis? (medifind.com)
Contact your provider for an appointment if you develop symptoms of toxoplasmosis. (medifind.com)

Anatomy4

Organisms6

Diseases25

Chemicals and Drugs16

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Phenomena and Processes7

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science1

Named Groups1

Health Care6

Geographicals3

Fetal cataract in congenital toxoplasmosis. (1/204)

Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy. (2/204)

The ocular manifestations of congenital infection: a study of the early effect and long-term outcome of maternally transmitted rubella and toxoplasmosis. (3/204)

Value of prenatal diagnosis and early postnatal diagnosis of congenital toxoplasmosis: retrospective study of 110 cases. (4/204)

A switch towards Th2 during serological rebound in children with congenital toxoplasmosis. (5/204)

Detection of specific immunoglobulin E during maternal, fetal, and congenital toxoplasmosis. (6/204)

Experimental toxoplasmosis in Balb/c mice. Prevention of vertical disease transmission by treatment and reproductive failure in chronic infection. (7/204)

Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens. (8/204)

Toxoplasmosis

Toxoplasmosis, Congenital

Toxoplasmosis, Ocular

Toxoplasmosis, Cerebral

Toxoplasma

Toxoplasmosis, Animal

Chorioretinitis

Antibodies, Protozoan

Sulfadiazine

Pregnancy Complications, Parasitic

Antiprotozoal Agents

Immunoglobulin M

Lung Diseases, Parasitic

Antigens, Protozoan

Immunoglobulin G

Seroepidemiologic Studies

DNA, Protozoan

AIDS-Related Opportunistic Infections

Choroiditis

Pregnancy

Enzyme-Linked Immunosorbent Assay

Serologic Tests

Atovaquone

Protozoan Vaccines

Antibody Affinity

Infant, Newborn

Pyrimethamine

Protozoan Proteins

Neonatal Screening

Parasitology

Acute Disease

Brazil

Uveitis, Posterior

Lymphadenitis

Coccidiostats

Pregnancy Complications, Infectious

Infectious Disease Transmission, Vertical

Skin Diseases, Parasitic

Sensitivity and Specificity

Immunocompromised Host

Immunoglobulin A

Polymerase Chain Reaction

Fatal Outcome

Naphthoquinones

Encephalitis

Food Parasitology

Agglutination Tests

Clindamycin

Cat Diseases

Prenatal Diagnosis

Suriname

Immunocompetence

Uveitis

Oocysts

HLA-B15 Antigen

Aborted Fetus

Kyrgyzstan

Amniotic Fluid

Trichechus manatus

Cats

Opportunistic Infections

Aqueous Humor

Hemagglutination Tests

Immunoassay

Parasite Load

Apicomplexa

Host-Parasite Interactions

Abortion, Veterinary

Central Nervous System Protozoal Infections

Eye Diseases

Retinitis

Animals, Domestic

Clinical Laboratory Techniques

Fetal Diseases

Protozoan Infections

Fetal cataract in congenital toxoplasmosis. (1/204)

Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy. (2/204)

The ocular manifestations of congenital infection: a study of the early effect and long-term outcome of maternally transmitted rubella and toxoplasmosis. (3/204)

Value of prenatal diagnosis and early postnatal diagnosis of congenital toxoplasmosis: retrospective study of 110 cases. (4/204)

A switch towards Th2 during serological rebound in children with congenital toxoplasmosis. (5/204)