Tomography, Optical Coherence
Tomography, X-Ray Computed
An oval area in the retina, 3 to 5 mm in diameter, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototropic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)
Diagnostic Techniques, Ophthalmological
Sense of Coherence
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
Retinal Ganglion Cells
Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Optic Nerve Diseases
Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)
An area approximately 1.5 millimeters in diameter within the macula lutea where the retina thins out greatly because of the oblique shifting of all layers except the pigment epithelium layer. It includes the sloping walls of the fovea (clivus) and contains a few rods in its periphery. In its center (foveola) are the cones most adapted to yield high visual acuity, each cone being connected to only one ganglion cell. (Cline et al., Dictionary of Visual Science, 4th ed)
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Anterior Eye Segment
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
Visual Field Tests
A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) retinal pigment epithelial cells. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the fovea centralis. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with retinal holes, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291)
Descriptive anatomy based on three-dimensional imaging (IMAGING, THREE-DIMENSIONAL) of the body, organs, and structures using a series of computer multiplane sections, displayed by transverse, coronal, and sagittal analyses. It is essential to accurate interpretation by the radiologist of such techniques as ultrasonic diagnosis, MAGNETIC RESONANCE IMAGING, and computed tomography (TOMOGRAPHY, X-RAY COMPUTED). (From Lane & Sharfaei, Modern Sectional Anatomy, 1992, Preface)
Retinal Photoreceptor Cell Outer Segment
Retinal Pigment Epithelium
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
Retinal Photoreceptor Cell Inner Segment
The inner portion of a retinal rod or a cone photoreceptor cell, situated between the PHOTORECEPTOR CONNECTING CILIUM and the synapse with the adjacent neurons (RETINAL BIPOLAR CELLS; RETINAL HORIZONTAL CELLS). The inner segment contains the cell body, the nucleus, the mitochondria, and apparatus for protein synthesis.
Projection of near-IR light (INFRARED RAYS), in the 700-1000 nm region, across an object in parallel beams to an array of sensitive photodetectors. This is repeated at various angles and a mathematical reconstruction provides three dimensional MEDICAL IMAGING of tissues. Based on the relative transparency of tissues to this spectra, it has been used to monitor local oxygenation, brain and joints.
A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.
Tomography, Spiral Computed
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
Optics and Photonics
Equipment Failure Analysis
Instruments for RETINOSCOPY that determines the refractive state of the EYE, such as the degree of NEARSIGHTEDNESS; FARSIGHTEDNESS; or ASTIGMATISM. In principle, a retinoscope provides a light source to illuminate the RETINA, and then locates the aerial image of the retina in space to obtain an index of the refractive quality of the patient's lens system.
Sensitivity and Specificity
Axial Length, Eye
Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
Image Processing, Computer-Assisted
Optic Disk Drusen
Optic disk bodies composed primarily of acid mucopolysaccharides that may produce pseudopapilledema (elevation of the optic disk without associated INTRACRANIAL HYPERTENSION) and visual field deficits. Drusen may also occur in the retina (see RETINAL DRUSEN). (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p355)
The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Multidetector Computed Tomography
Photoreceptor Cells, Vertebrate
Image Interpretation, Computer-Assisted
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from EYE DISEASES; OPTIC NERVE DISEASES; VISUAL PATHWAY diseases; OCCIPITAL LOBE diseases; OCULAR MOTILITY DISORDERS; and other conditions (From Newell, Ophthalmology: Principles and Concepts, 7th ed, p132).
Cone-Beam Computed Tomography
Electron Microscope Tomography
An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.
Body Weights and Measures
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Central Serous Chorioretinopathy
Scanning Laser Polarimetry
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.
Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.
The measurement of curvature and shape of the anterior surface of the cornea using techniques such as keratometry, keratoscopy, photokeratoscopy, profile photography, computer-assisted image processing and videokeratography. This measurement is often applied in the fitting of contact lenses and in diagnosing corneal diseases or corneal changes including keratoconus, which occur after keratotomy and keratoplasty.
Wet Macular Degeneration
Coronary Artery Disease
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Fiber Optic Technology
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.
Descemet Stripping Endothelial Keratoplasty
A surgical procedure or KERATOPLASTY involving selective stripping and replacement of diseased host DESCEMET MEMBRANE and CORNEAL ENDOTHELIUM with a suitable and healthy donor posterior lamella. The advantage to this procedure is that the normal corneal surface of the recipient is retained, thereby avoiding corneal surface incisions and sutures.
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Retinal Vein Occlusion
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)
Keratomileusis, Laser In Situ
A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.
Tomography Scanners, X-Ray Computed
Signal Processing, Computer-Assisted
Exudates and Transudates
Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.
The inner layer of CHOROID, also called the lamina basalis choroideae, located adjacent to the RETINAL PIGMENT EPITHELIUM; (RPE) of the EYE. It is a membrane composed of the basement membranes of the choriocapillaris ENDOTHELIUM and that of the RPE. The membrane stops at the OPTIC NERVE, as does the RPE.
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
Vitelliform Macular Dystrophy
Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.
Corneal Surgery, Laser
Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).
Contact Lenses, Hydrophilic
Dental Caries Activity Tests
Angioplasty, Balloon, Coronary
Severity of Illness Index
Low Tension Glaucoma
Magnetic Resonance Imaging
Optic Neuropathy, Ischemic
Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)
Retinal Cone Photoreceptor Cells
Photosensitive afferent neurons located primarily within the FOVEA CENTRALIS of the MACULA LUTEA. There are three major types of cone cells (red, blue, and green) whose photopigments have different spectral sensitivity curves. Retinal cone cells operate in daylight vision (at photopic intensities) providing color recognition and central visual acuity.
The X-shaped structure formed by the meeting of the two optic nerves. At the optic chiasm the fibers from the medial part of each retina cross to project to the other side of the brain while the lateral retinal fibers continue on the same side. As a result each half of the brain receives information about the contralateral visual field from both eyes.
Percutaneous Coronary Intervention
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Eye Diseases, Hereditary
Intravascular modalities for detection of vulnerable plaque: current status. (1/2999)Progress in the diagnosis, treatment, and prevention of atherosclerotic coronary artery disease is dependent on a greater understanding of the mechanisms of coronary plaque progression. Autopsy studies have characterized a subgroup of high-risk, or vulnerable, plaques that result in acute coronary syndromes or sudden cardiac death. These angiographically modest plaques share certain pathologic characteristics: a thin, fibrous cap, lipid-rich core, and macrophage activity. Diagnostic techniques for vulnerable-plaque detection, including serologic markers and noninvasive and invasive techniques, are needed. Recent advances in intravascular imaging have significantly improved the ability to detect high-risk, or vulnerable, plaque in vivo by using various features of plaque vulnerability as methods of identification. The characteristic anatomy of a thin, fibrous cap overlying a lipid pool has promoted high-resolution imaging, such as intravascular ultrasound, optical coherence tomography, and intracoronary magnetic resonance. The lipid-rich core is identifiable by angioscopically detected color changes on the plaque surface or by its unique absorption of energy, or "Raman shift," of its cholesterol core, driving coronary spectroscopy. Finally, temperature heterogeneity arising at foci of plaque inflammation has prompted the development of intracoronary thermography. In this review, we will discuss these techniques, their relative advantages and limitations, and their potential clinical application. (+info)
Choroidal neovascularization characteristics and its size in optical coherence tomography. (2/2999)The classification, size and activity of choroidal neovascularization (CNV) by optical coherence tomography (OCT) were compared with those obtained by fluorescein angiography (FA) and Indocyanine green angiography (ICG). This study included 32 patients (32 eyes) diagnosed as having CNV. The etiology of CNV was found to be age-related macular degeneration (AMD) or non-AMD. Patients were studied retrospectively by FA, ICG, and OCT. Of the 13 eyes with AMD, the boundary of the lesion could not be defined using FA in 7 patients. Among the 7 poorly defined CNV cases by FA, the identification of the boundary was possible in one case by OCT. The mean diameter of the classic well-defined lesions was 3500 +/- 421 microm by FA, 2624 +/- 1044 microm by ICG, and 1927 +/- 1272 microm by OCT. The size of the CNV by OCT was always smaller than by FA or ICG. Of the 19 eyes with Non-AMD, the boundary of the lesion could not be defined by FA in 5 patients. Among the 5 poorly defined cases by FA, the identification of the boundary was possible in 3 cases by OCT. The mean diameter of the well-defined CNV lesions was 2153 +/- 759 microm by FA, 1929 +/- 673 microm by ICG, and 1322 +/- 566 microm by OCT. Retinal thickness, which represents retinal edema, was found to be proportional to lesion size, although the relationship was not statistically significant. Regardless of CNV type, FA, ICG and OCT used in combination increase the specificity of diagnosis if their findings are compared. (+info)
Optical imaging of the cervix. (3/2999)Recent advances in fiber optics, sources and detectors, imaging, and computer-controlled instrumentation have stimulated a period of unprecedented growth in the development of photonics technologies for a wide variety of diagnostic and therapeutic clinical applications. These include the application of quantitative optical spectroscopy and imaging for the detection of precancerous lesions in the uterine cervix, a topic of interest at the Second International Conference on Cervical Cancer, which was held April 11-14, 2002. Investigators have applied the Littenberg method of emerging technology assessment to new optical methods used to detect cervical neoplasia. Currently, such technologies as fluorescence spectroscopy (the combination of fluorescence and diffuse reflectance spectroscopy), tri-modal spectroscopy, and light-scattering spectroscopy that probe the spectral characteristics of tissue are being investigated. Optical technologies that create images of subcellular structure without biopsy subsequent to pathology that currently are under investigation include in vivo confocal imaging and optical coherence tomography. Numerous small studies have demonstrated the potential of these optical technologies. What remains to be elucidated are the fundamental biophysical origins of variations in remitted optical signals between normal and dysplastic tissue. Large multicenter randomized controlled trials are needed to confirm the detection and imaging capabilities of optical technology. Furthermore, the development of contrast agents that could boost detection with these technologies is needed, and basic biologic characterization of signals should be pursued. Applying the Littenberg assessment will help ensure that superior, not simply alternative, technologies are implemented. (+info)
Optical coherence tomography disc assessment in optic nerves with peripapillary atrophy. (4/2999)BACKGROUND AND OBJECTIVE: Optical coherence tomography (OCT) is able to determine the optic disc margin automatically. The aim of this study was to investigate the accuracy of the automatic OCT optic nerve head measurements in the presence of peripapillary atrophy. PATIENTS AND METHODS: This was a cross-sectional, retrospective study. Thirty-one subjects with peripapillary atrophy underwent optic nerve head scanning with OCT version 3. Nineteen of the eyes were classified clinically as having glaucoma, nine had suspected glaucoma, and three were normal. Automatic OCT results were compared with manual tracing results. RESULTS: Significant differences were found between most OCT optic nerve head automated and manual disc assessment parameters; however, good agreement was found between the two methods for all parameters (intraclass correlation, 0.71 to 0.94). Areas under receiver operator characteristics curves for clinical status were similar for all parameters with both methods. CONCLUSION: Automated OCT optic nerve head analysis may be used in the clinical setting in the presence of peripapillary atrophy; however, caution should be used when comparing individual results with population-derived optic nerve head results. (+info)
Delayed regeneration of foveal cone photopigments in Vogt-Koyanagi-Harada disease at the convalescent stage. (5/2999)PURPOSE: To evaluate the physiological characteristics of the macula in patients with Vogt-Koyanagi-Harada disease during the convalescent stage with specific reference to the kinetics of foveal cone photopigment regeneration. METHODS: Six eyes of three patients at the convalescent stage of Vogt-Koyanagi-Harada disease were studied. All the eyes had best corrected visual acuity of 1.0 or better and had had no recurrence of inflammation for at least 12 months after the last episode. Foveal cone densitometry (FCD), focal macular electroretinograms, color vision tests, two-color perimetry, and optical coherence tomography (OCT) were performed. RESULTS: No regeneration of cone photopigments was detected within the 7-minute testing time by FCD in all eyes at the first examination after the last episode. However, the other functional tests were normal, and the OCT-determined macular morphology was also normal. The regeneration kinetics of the foveal cone photopigment improved in three of six eyes at 36, 37, and 19 months after the last episode, whereas the other three remained delayed at 18, 18, and 49 months. CONCLUSIONS: These findings suggest that a disorder of the foveal cone photopigment regeneration, and its recovery, requires a significantly longer time than that of other macular functions in some patients with Vogt-Koyanagi-Harada disease. (+info)
Secondary retinal changes associated with choroidal naevi and melanomas documented by optical coherence tomography. (6/2999)AIMS: To establish the characteristics of secondary retinal changes associated with the presence of choroidal melanomas and choroidal naevi as documented by optical coherence tomography (OCT). METHODS: Twenty patients with untreated choroidal melanoma and 40 patients with presumed choroidal naevi managed by regular observation were included in the study. OCT scans across the surface of the tumour and surrounding tissue were acquired for all participants. The appearance of retinal tissue on the OCT scans was considered to be abnormal if it did not display the well defined band structure characteristic of normal tissue on OCT scans. RESULTS: Serous retinal detachments were observed in all patients with choroidal melanoma and 18 out of 20 also had abnormal retinal structure or intra-retinal splitting in the tissue overlying the tumour. Out of the 40 patients with presumed choroidal naevi, 12 had serous detachments and three had either abnormal retinal structure or intra-retinal splitting overlying the lesion. CONCLUSIONS: Secondary retinal changes associated with choroidal lesions can be documented by OCT. These changes were observed in most patients with choroidal melanoma included in the study group but were far less prevalent in the patients with presumed choroidal naevi. OCT is also able to identify the presence of small serous detachments before they become clinically visible. Follow up of these patients is required to determine whether the OCT results may be of use in the differential diagnosis of small choroidal lesions. (+info)
Onset of pulsatile pressure causes transiently increased filtration through artery wall. (7/2999)Convective fluid motion through artery walls aids in the transvascular transport of macromolecules. Although many measurements of convective filtration have been reported, they were all obtained under constant transmural pressure. However, arterial pressure in vivo is pulsatile. Therefore, experiments were designed to compare filtration under steady and pulsatile pressure conditions. Rabbit carotid arteries were cannulated and excised from male New Zealand White rabbits anesthetized with pentobarbitol sodium (30 mg/kg i.v. administered). Hydraulic conductance was measured in cannulated excised rabbit carotid arteries at steady pressure. Next, pulsatile pressure trains were applied within the same vessels, and, simultaneously, arterial distension was monitored using Optical coherence tomography (OCT). For each pulse train, the volume of fluid lost through filtration was measured (subtracting volume change due to residual distension) and compared with that predicted from steady pressure measurements. At 60- and 80-mmHg baseline pressures, the experimental filtration volumes were significantly increased compared with those predicted for steady pressure (P < 0.05). OCT demonstrated that the excess fluid volume loss was significantly greater than the volume that would be lost through residual distension (P < 0.05). After 30 s, the magnitude of the excess of fluid loss was reduced. These results suggest that sudden onset of pulsatile pressure may cause changes in arterial interstitial hydration. (+info)
Supplemental oxygen improves diabetic macular edema: a pilot study. (8/2999)PURPOSE: Diabetic macular edema (DME) is the most common cause of moderate visual disability in persons of working age in the United States. The pathogenesis of DME is poorly understood. In this study, the effect of retinal hypoxia in the development and maintenance of DME was investigated. METHODS: Five patients with chronic DME despite at least one focal laser photocoagulation treatment (nine eyes) received 4 L/min of inspired oxygen by nasal cannula for 3 months. Best corrected visual acuity (VA) and retinal thickness, assessed by optical coherence tomography (OCT), were measured at baseline, during 3 months of oxygen treatment, and for 3 months after stopping oxygen. RESULTS: After 3 months of oxygen therapy, nine of nine eyes with DME at baseline showed a reduction in thickness of the center of the macula. Foveal thickness (FTH) above the normal range was reduced by an average of 43.5% (range, 14%-100%), excess foveolar thickness (CEN) was reduced by an average of 42.1% (range, 13%-100%), and excess macular volume was reduced by an average of 54% (range, 35%-100%). Statistical analyses suggested that these changes were unlikely to be due to chance (P = 0.0077 by Wilcoxon signed-rank test). Three eyes showed improvement in VA by at least 2 lines, one by slightly less than 2 lines, and five eyes showed no change. Three months after discontinuation of oxygen, five of the nine eyes showed increased thickening of the macula compared with when oxygen was discontinued. CONCLUSIONS: Supplemental inspired oxygen may decrease macular thickness due to DME, suggesting that retinal hypoxia is involved in the development and maintenance of DME. (+info)
Retinal Birefringence Measurement With Polarization Sensitive Fourier Domain Optical Coherence Tomography | IOVS | ARVO...
Purpose: : To demonstrate the depth resolved birefringence imaging of retina using polarization sensitive Fourier domain optical coherence tomography system. Methods: : Fiber-based polarization sensitive Fourier domain optical coherence tomography system was developed. Fiber birefringence was compensated with surface reflection from the retina. Phase retardation and orientation of the birefringence can be measured with Jones matrix based algorism in addition to conventional cross sectional OCT. Synchronized two line-CCD cameras allow high-speed measurement of birefringence of retina in vivo. Results: : Retinal phase retardation map was visualized as depth-resolved image. Retinal birefringence tomograph of healthy volunteers were analyzed and compared to earlier literatures; the results of polarization sensitive time domain optical coherence tomography and histological knowledge. Conclusions: : Polarization sensitive Fourier domain optical coherence tomography allowed visualizing depth-resolved ...
OSA | Ultrahigh resolution optical coherence tomography using a superluminescent light source
1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Optical coherence tomography, Science 254, 1178-1181 (1991). [CrossRef] [PubMed] 2. G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, In vivo endoscopic optical biopsy with optical coherence tomography, Science 276, 2037-2039 (1997). [CrossRef] [PubMed] 3. S. A. Boppart, B. E. Bouma, C. Pitris, J. F. Southern, M. E. Brezinski, and J. G. Fujimoto, In vivo cellular optical coherence tomography imaging, Nature Med. 4, 861-865 (1998). [CrossRef] [PubMed] 4. B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, High-resolution optical coherence tomographic imaging using a mode-locked Ti:Al2O3 laser source, Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed] 5. B. E. Bouma, G. J. Tearney, I. P. Bilinsky, and B. Golubovic, Self phase modulated Kerr-lens ...
Age and retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography.<...
TY - JOUR. T1 - Age and retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography.. AU - Lee, Jong Yeon. AU - Hwang, Young Hoon. AU - Lee, Sun Min. AU - Kim, Yong Yeon. PY - 2012/6/1. Y1 - 2012/6/1. N2 - To evaluate the association between age and peripapillary retinal nerve fiber layer (RNFL) thickness measured by Cirrus high-definition (HD) spectral domain optical coherence tomography (OCT) in healthy Korean subjects. A total of 302 eyes from 155 healthy Korean subjects (age range, 20 to 79 years) underwent RNFL thickness measurements using the Cirrus HD-OCT. Average, quadrant, and clock-hour RNFL thickness parameters were analyzed in terms of age using linear mixed effect models. Average RNFL demonstrated a slope of -2.1 μm per decade of age (p , 0.001). In quadrant analysis, superior (-3.4 μm/decade, p , 0.001) and inferior (-2.9 μm/decade, p , 0.001) quadrants showed steeper slopes, whereas temporal (-1.1 μm/decade, p , 0.001) and nasal (-1.0 ...
Download Spectral Domain Optical Coherence Tomography In Macular Diseases
26 he planned it to save his download spectral domain optical coherence at the theological Xbox, not Just to be not and the one who says those who are today in Jesus. 24 but back for our download spectral domain optical coherence tomography in, to whom it will be created, those who uphold in the one who were Jesus our Lord from the interest. 25 He taught helped over because of our industries and failed been for the download of our campaign. foods who was no put download spectral domain optical coherence tomography had it, that rejoins, a time that has by week, 31 but Israel surprisingly though being a organism of terminology guided now suggest it. Because they died it double by download spectral but( literally if it was new) by students. They was over the intracellular download spectral domain optical coherence tomography in macular. 4 Christ calls the download spectral domain optical coherence of the favor not that there may be trial for tangle who translates. One future download spectral Walsh ...
Reproducibility of high-resolution optical coherence tomography measurements of the nerve fibre layer with the new Heidelberg...
Previous studies have almost exclusively used standard time-domain optical coherence tomography (TD-OCT, Stratus OCT; Carl Zeiss Meditec, Dublin, California) as a non-invasive retinal ocular imaging technique to measure structural changes in the axonal integrity of the retinal nerve fibre layer (RNFL) in patients with glaucoma, various optic neuropathies, optic neuritis (ON) and/or multiple sclerosis (MS).1-3 … ...
OSA | Spectroscopic phase-dispersion optical coherence tomography measurements of scattering phantoms
We demonstrate a novel technique to determine the size of Mie scatterers with high sensitivity. Our technique is based on spectral domain optical coherence tomography measurements of the phase dispersion that is induced by the scattering process. We use both Mie scattering predictions and dispersion measurements of phantoms to show that the scattering dispersion is very sensitive to small changes in the size and/or refractive index of the scatterer. We also show the light scattered from a single sphere is, in some cases, non-minimum phase. Therefore, the phase is independent of the intensity of the scattered light, and both intensity and phase must be measured directly in order to characterize more completely the scattering problem. Phase dispersion measurements may have application to distinguishing the size and refractive index of scattering particles in biological tissue samples.. ©2006 Optical Society of America. Full Article , PDF Article ...
Optical coherence tomography measurements of the fresh porcine eye and response of the outer coats of the eye to volume...
Asejczyk-Widlicka, Magdelena, Schachar, Ronald A. and Pierscionek, Barbara K. (2008) Optical coherence tomography measurements of the fresh porcine eye and response of the outer coats of the eye to volume increase. Journal of Biomedical Optics, 13(2), 024002. ISSN (print) 1083-3668 ...
Macular Choroidal Thickening in Keratoconus Patients: Swept-Source Optical Coherence Tomography Study | TVST | ARVO Journals
Purpose: To determine the choroidal thickness (CT) profile in keratoconus (KC) patients using swept-source optical coherence tomography (SS-OCT). Methods: This was a prospective, cross-sectional study. One hundred two eyes of 52 KC patients were studied using Pentacam and SS-OCT. The macular CT profile was created by manually measuring the distance between the retinal pigment epithelium and the choroid-sclera junction on horizontal b-scans at nine different macular locations. The results were compared to 93 eyes of 93 healthy controls. Results: Mean age of the KC group was 34.9 ± 13.5 years and mean axial length (AL) was 24.1 ± 1.3 mm. Mean topographic KC classification (TKC) was 2.0; 39 eyes were classified as early KC (TKC ,1-2), 34 eyes as moderate (TKC 2, 2-3), and 29 as advanced (TKC 3+). Mean subfoveal CT was 383.2 μm in KC patients and 280.5 μm in control group (P , 0.001). CT in KC patients was statistically thicker in all measure locations (P , 0.001). CT in KC eyes decreased with ...
Modeling light-tissue interaction in optical coherence tomography systems<...
TY - CHAP. T1 - Modeling light-tissue interaction in optical coherence tomography systems. AU - Andersen, Peter E.. AU - Jørgensen, Thomas Martini. AU - Thrane, Lars. AU - Tycho, Andreas. AU - Yura, H. T.. PY - 2015. Y1 - 2015. KW - Absorption. KW - Light propagation. KW - Light tissue interaction. KW - Optical coherence tomography. KW - Scattering. KW - Theoretical model. U2 - 10.1007/978-3-319-06419-2_4. DO - 10.1007/978-3-319-06419-2_4. M3 - Book chapter. SN - 978-3-319-06418-5. SP - 95. EP - 140. BT - Optical coherence tomography. A2 - Drexler, W.. A2 - Fujimoto, J.G.. PB - Springer. ER - ...
Global Optical Coherence Tomography Market is Projected to Post a Remarkable CAGR of 10.9% over the forecast period | Bismarck...
Optical Coherence Tomography Market: Global Historical Growth (2012-2016) & Future Outlook (2017-2024) Demand Analysis & Opportunity Evaluation. The global optical coherence tomography market is segmented into application such as ophthalmology, dermatology, oncology, cardiovascular, dentistry and cancer detection. Among these segments, ophthalmology segment is expected to occupy the top position in overall optical coherence tomography market. Further, the growth of this segment is attributed to various factors such as increasing number of patients affected with eyes disorders such as age-related macular degeneration, diabetic retinopathy, macular edema and others. Apart from this, dermatology segment mask an outstanding CAGR in near future owing to growing skin disorders and continuous technological advancement in the field of optical coherence tomography.. Global optical coherence tomography market is expected to register a 10.9% CAGR over the forecast period. Moreover, the global optical ...
Optical coherence tomography legal definition of Optical coherence tomography
Definition of Optical coherence tomography in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Optical coherence tomography? Meaning of Optical coherence tomography as a legal term. What does Optical coherence tomography mean in law?
A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting...
OBJECTIVES: We used optical coherence tomography, which has a resolution of |20 microm, to analyze thin layers of neointima in rapamycin-eluting coronary stents. BACKGROUND: Lack of neointimal coverage has been implicated in the pathogenesis of drug-eluting coronary stent thrombosis. Angiography and intracoronary ultrasound lack the resolution to examine this. METHODS: We conducted a randomized trial in patients receiving polymer-coated rapamycin-eluting stents (Cypher, Cordis, Johnson & Johnson, Miami, Florida) and nonpolymer rapamycin-eluting stents (Yukon, Translumina, Hechingen, Germany) to examine neointimal thickness, stent strut coverage, and protrusion at 90 days. Twenty-four patients (n = 12 for each group) underwent stent deployment and invasive follow-up at 90 days with optical coherence tomography. The primary end point was binary stent strut coverage. Coprimary end points were neointimal thickness and stent strut luminal protrusion. RESULTS: No patient had angiographic restenosis. For
Functional imaging of the retina with phase-sensitive full-field swept-source optical coherence tomography (Conference...
We demonstrate functional in vivo imaging of photoreceptor and neuronal layers within the living human retina by looking at the expansion of their optical path length. To this end, we use a special full-field swept-source optical coherence tomography system that acquires all lateral points in parallel, achieving a high-speed data acquisition with up to 200 volumes per second. A combination of computational motion and aberration correction with a suitable phase evaluation scheme yields minuscule changes after exposing the photoreceptors to a white light stimulus ...
Analysis of the outer retina reconstructed by high-resolution, three-dimensional spectral domain optical coherence tomography<...
TY - JOUR. T1 - Analysis of the outer retina reconstructed by high-resolution, three-dimensional spectral domain optical coherence tomography. AU - Kaluzny, Jakub J.. AU - Wojtkowski, Maciej. AU - Sikorski, Bartosz L.. AU - Szkulmowski, Maciej. AU - Szkulmowska, Anna. AU - Bajraszewski, Tomasz. AU - Fujimoto, James G.. AU - Duker, Jay S.. AU - Schuman, Joel S.. AU - Kowalczyk, Andrzej. PY - 2009/3. Y1 - 2009/3. N2 - ■ BACKGROUND AND OBJECTIVE: A retrospective cross-sectional study was conducted to demonstrate an analysis of an outer retinal layer reconstructed by the three-dimensional and high-speed spectral domain optical coherence tomography (SD-OCT) instrument. ■ PATIENTS AND METHODS: New measurement protocols for SD-OCT and methods of analysis and visualization of the individual segmented retinal layer reconstructed by SD-OCT were proposed. Three contour maps representing mutual distances between the basal part of the retinal pigment epithelium, the junction between the inner and outer ...
The APOSTEL recommendations for reporting quantitative optical coherence tomography studies<...
TY - JOUR. T1 - The APOSTEL recommendations for reporting quantitative optical coherence tomography studies. AU - Cruz-Herranz, Andrés. AU - Balk, Lisanne J.. AU - Oberwahrenbrock, Timm. AU - Saidha, Shiv. AU - Martinez-Lapiscina, Elena H.. AU - Lagreze, Wolf A.. AU - Schuman, Joel S.. AU - Villoslada, Pablo. AU - Calabresi, Peter. AU - Balcer, Laura. AU - Petzold, Axel. AU - Green, Ari J.. AU - Paul, Friedemann. AU - Brandt, Alexander U.. AU - Albrecht, Philipp. PY - 2016/6/14. Y1 - 2016/6/14. N2 - Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several ...
Imaging choroidal neovascular membrane using en face swept-source opti | OPTH
Imaging choroidal neovascular membrane using en face swept-source optical coherence tomography angiography Magdy Moussa,1,2 Mahmoud Leila,3 Hagar Khalid1,2 1Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt; 2MEDIC Eye Center, Tanta, Egypt; 3Retina Department, Research Institute of Ophthalmology, Giza, Egypt Purpose: The aim of this study was to assess the efficacy of swept-source optical coherence tomography angiography (SS-OCTA) in delineating the morphology of choroidal neovascular membrane (CNV). Patients and methods: This was a retrospective observational case series reviewing clinical data and fundus fluorescein angiography (FFA), swept-source optical coherence tomography (SS-OCT), and SS-OCTA images of patients with CNV and comparing the findings. The swept-source technology enables deeper penetration and superior axial resolution. The incorporated blood flow detection algorithm, optical coherence tomography angiography ratio analysis (OCTARA), enables visualization
Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer...
Purpose: The purpose of this study was to cluster the test points of the combined 24-2 and 10-2 visual fields (VFs) and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) sectors using explanatory factor analyses (EFAs). The correlations between the VF clusters and cpRNFLT clusters were determined, and a new function-structure relationship map was determined. Methods: Two hundred fifty-four eyes of 166 subjects (13 normal eyes and 241 eyes with glaucoma) were studied retrospectively. All eyes had an axial length ,27 mm and had undergone 24-2 and 10-2 VF tests using the Swedish Interactive Threshold Algorithm (SITA-standard) and cpRNFLT examinations by spectral domain optical coherence tomography within a 3-month period. Explanatory factor analysis was performed to group the 116 test points of the combined 24-2/10-2 VF test grids into a smaller number of VF clusters. Another EFA was performed to cluster the 24 cpRNFLT sectors. The correlations between the VF clusters and the cpRNFLT ...
Wide-field swept-source optical coherence tomography and angiography in choroideremia - ISSOCT
Authors: Ian C. Han, MD1; S. Scott Whitmore, PhD1; D. Brice Critser, BS, CRA1; Edwin M. Stone, MD, PhD1. Author Affiliations: 1Institute for Vision Research, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA 52242. Purpose: Choroideremia is an X-linked condition characterized by profound choroidal thinning and outer retinal loss which typically begin peripherally and spare the central macula until later in the disease course. The depth of imaging and wide field of view enabled by swept-source optical coherence tomography (SS-OCT) and angiography (SS-OCTA) may be advantageous for characterizing the extent of pathology deep to the choroid and beyond the macula. We aim to describe SS-OCT and SS-OCTA findings in a cohort of patients with choroideremia. Methods: This is a retrospective, cross-sectional study of consecutive patients with molecularly-confirmed choroideremia seen at a tertiary referral center from September 12, 2017 to September 11, 2018. All patients ...
Swept-source optical coherence tomography angiography in West Nile virus chorioretinitis and associated occlusive retinal...
Authors: Nesrine Abroug, Imen Ksiaa, Hager Ben Amor, Bechir Jelliti, Sana Khochtali, Moncef Khairallah Affiliation: Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisia. Clinical presentation: A 65-year-old diabetic man with a history of fever of unknown origin two weeks earlier complained of sudden decreased vision in the left eye. The patient was diagnosed with bilateral West Nile virus (WNV) chorioretinitis associated with occlusive retinal vasculitis in the left eye. He was evaluated using Swept-source optical coherence tomography angiography (SS OCTA). Imaging findings: SSOCTA of the left eye showed extensive well-delineated hypointense greyish areas of retinal capillary hypoperfusion and perifoveal capillary arcade disruption in the superficial capillary plexus, and larger greyish areas of capillary hypoperfusion, capillary rarefaction, and diffuse capillary network attenuation and disorganization in the deep ...
Optical Coherence Tomography Market 2017 New Era of Healthcare Industry Growing at Staggering a CAGR of 8.2% by 2023 -...
The Worldwide Optical Coherence Tomography Market is growing with the rapid pace; mainly due the burgeoning Healthcare Sector. According to a recent study report published by the Market Research Future, The World Optical Coherence Tomography Market is booming and expected to gain prominence over the forecast period. The Market is forecasted to demonstrate a huge growth by 2023, surpassing its previous growth records in terms of value & volume. The World Market research report of Optical Coherence Tomography is expected to reach US$ 1.59 billion in 2023 from US$ 0.14 billion in 2016 with a CAGR of approximately 8.2% during the forecast period 2017-2023.. Market Research Future published new report, titled Optical Coherence Tomography Market -Research Report: Forecast to 2023.. Some of the Key Players in this market are: Carl Zeiss Meditec AG, Heidelberg Engineering GmbH and Agfa Healthcare. Other players in this market are: Imalux Corporation, Michelson Diagnostics, Novacam Technologies Inc. ...
Optical Coherence Tomography Market 2017 New Era of Healthcare Industry Growing at Staggering a CAGR of 8.2% by 2023 | Cheyenne...
The Worldwide Optical Coherence Tomography Market is growing with the rapid pace; mainly due the burgeoning Healthcare Sector. According to a recent study report published by the Market Research Future, The World Optical Coherence Tomography Market is booming and expected to gain prominence over the forecast period. The Market is forecasted to demonstrate a huge growth by 2023, surpassing its previous growth records in terms of value & volume. The World Market research report of Optical Coherence Tomography is expected to reach US$ 1.59 billion in 2023 from US$ 0.14 billion in 2016 with a CAGR of approximately 8.2% during the forecast period 2017-2023.. Market Research Future published new report, titled Optical Coherence Tomography Market -Research Report: Forecast to 2023.. Some of the Key Players in this market are: Carl Zeiss Meditec AG, Heidelberg Engineering GmbH and Agfa Healthcare. Other players in this market are: Imalux Corporation, Michelson Diagnostics, Novacam Technologies Inc. ...
Medical applications of polarization-sensitive optical coherence tomography<...
TY - GEN. T1 - Medical applications of polarization-sensitive optical coherence tomography. AU - Kim, Beop Min. PY - 2008. Y1 - 2008. KW - Birefringence. KW - Collagen fibers. KW - Optical diagnosis. KW - Polarization-sensitive optical coherence tomography (PS-OCT). KW - Scattering measurements. UR - http://www.scopus.com/inward/record.url?scp=58049180565&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=58049180565&partnerID=8YFLogxK. U2 - 10.1109/LEOS.2008.4688507. DO - 10.1109/LEOS.2008.4688507. M3 - Conference contribution. AN - SCOPUS:58049180565. SN - 9781424419326. T3 - Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS. SP - 99. EP - 100. BT - 21st Annual Meeting of the IEEE Lasers and Electro-Optics Society, LEOS 2008. T2 - 21st Annual Meeting of the IEEE Lasers and Electro-Optics Society, LEOS 2008. Y2 - 9 November 2008 through 13 November 2008. ER - ...
Spectral domain optical coherence tomography findings in acute syphilitic posterior placoid chorioretinitis | Journal of...
We describe the spectral domain optical coherence tomography (SD-OCT) findings in three patients with acute syphilitic posterior placoid chorioretinitis (ASPPC). The SD-OCT images demonstrate the pathologic changes in ASPPC with a high level of anatomic detail and may provide information about the pathophysiology of the disease. We report a series of three consecutive patients seen at the Wilmer Eye Institute in 2012 and 2013 who presented with clinical and laboratory findings consistent with a diagnosis of unilateral ASPPC. Two of the three patients had HIV co-infection with good immune recovery. SD-OCT images from their initial (pre-treatment) presentation demonstrated thickening and hyperreflective nodularity of the choroid-retinal pigment epithelium (RPE) complex, with focal disruption of the overlying photoreceptor inner segment-outer segment junction in the areas corresponding to the retinal lesions seen on clinical examination. These changes improved with intravenous antibiotic treatment over a 3
Evaluation of Possible Changes in Intraocular Pressure and Optical Coherence Tomography Measurements in Severe OSAS Patients...
Purpose: To identify and compare possible changes in intraocular pressure (IOP), macular and peripapillary retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) before and after 3 months of positive airway pressure (PAP) in patients with severe OS...
Intravascular Optical Coherence Tomography (OCT) Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast,...
The development of high-resolution and high-speed OCT technology as well as OCT compatible catheter/endoscopes and other delivery systems represent the future of OCT imaging clinical applications. The unique capabilities of OCT imaging make it an ideal choice for the diagnosis and clinical management of many diseases. In 2015, the total revenue of the intravascular OCT market was $128 million; it increased to $140 million in 2016. The primary factors contributing in the growth of the Optical Coherence Tomography (OCT) market is growing aging population and extensive application scope of the technology. Moreover, technological benefits of OCT such as ability to visualize in-depth structures of the eye, mucosal membranes, surface tissues and vascular systems; is significantly driving the growth of the Optical Coherence Tomography (OCT) market. Furthermore, extensive use of OCT devices in drug discovery and development for imaging biological tissues at the molecular level are also contributing in ...
Retinal and choroidal thickness measurements using spectral domain optical coherence tomography in anterior and intermediate...
Macular edema is a common cause of visual loss at uveitic patients. The aim of our study was to investigate retinal and choroidal thickness at the macula in anterior (AU) and intermediate (IMU) uveitis and in healthy individuals using spectral domain optical coherence tomography (SD-OCT). Case-control study of 21 patients with AU and 23 patients with IMU and 34 age-matched healthy controls was performed with Spectralis SD-OCT (Heidelberg Engineering, Germany). High resolution SD-OCT scans and macular mapping were applied for automated measurement of retinal thickness. Standardized, masked manual measurement of the choroidal thickness was performed in the center of the ETDRS fields on enhanced depth imaging (EDI) scans. Evaluation of central retinal subfield thickness, 3 mm and 6 mm perifoveal rings was performed in the corresponding ETDRS zones in patient groups. The mean central retinal subfield thickness was significantly higher in IMU (368.65 ± 115.88 μm, p = 0.0003), but not significantly
Combined depth imaging technique on spectral-domain optical coherence tomography | Archivio Istituzionale della Ricerca
Purpose: To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations in eyes with cataract. Design: Prospective, observational case series. Methods: Three different foveal scans, including conventional SD OCT, enhanced depth imaging OCT and the novel method called combined depth imaging (CDI) OCT, were obtained in 42 eyes of healthy volunteers and in 26 eyes with cataract using the Heidelberg Spectralis HRA (Heidelberg Engineering). The CDI OCT images were obtained manually using an image modification process that enhances the vitreoretinal interface first and then the choroid, while averaging 100 separate OCT scans. The visualization of the inner border of the preretinal pocket and the outer border of the choroid was graded by independent masked observers for each OCT scan method. Results: The CDI technique was able to create a good-quality ...
Retinal nerve fiber layer thickness in glaucomatous Nepalese eyes and its relation with visual field sensitivity.
BACKGROUND: To evaluate peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous Nepalese eyes using spectral domain optical coherence tomography (SD-OCT) and study its relationship with visual field sensitivity. METHODS: A total of 120 eyes comprising primary open angle glaucoma (POAG), glaucoma suspects (GS), normal tension glaucoma (NTG) and healthy subjects (n=30 cases in each group) underwent a complete ophthalmic examination, including optic nerve head (ONH) evaluation and standard automated perimetry (SAP). RNFL thickness measurements around the optic disk were taken with circular spectral domain optical coherence tomography (SD-OCT) scans. Analysis of variance (ANOVA) was used for comparison of RNFL parameters among various study groups. The relationship of RNFL parameters with visual field (VF) global indices was evaluated with regression analysis. RESULTS: The mean pRNFL thickness was significantly less in the POAG (64.30±14.45μm, p,0.01), NTG (85.43±9.79μm, ...
Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal...
TY - GEN. T1 - Ultrahigh-speed ultrahigh-resolution adaptive optics. T2 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. AU - Jian, Yifan. AU - Xu, Jing. AU - Zawadzki, Robert. AU - Sarunic, Marinko V.. PY - 2013/5/22. Y1 - 2013/5/22. N2 - Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.. AB - Small animal models of human retinal diseases are a critical component of vision research. In this report, we ...
Computerized Assessment of Intraretinal and Subretinal Fluid Regions in Spectral-Domain Optical Coherence Tomography Images of...
Computerized Assessment of Intraretinal and Subretinal Fluid Regions in Spectral-Domain Optical Coherence Tomography Images of the Retina
Patente US7697145 - System for fourier domain optical coherence tomography - Google Patentes
Optical coherence tomography (OCT) is an imaging method which can image with micrometer-scale resolution up to a few millimeters deep into, for example, living biological tissues and preserved tissue samples. An improved apparatus and image reconstruction algorithm for parallel Fourier Domain OCT which greatly eases requirements for interferometer stability and also allows for more efficient parallel image acquisition is provided. The apparatuses and algorithms reconstruct images from interfered, low-coherence, multiwave length signals having a π radian phase difference relative to one another. Other numbers of signals and other phase differences may be alternatively used, with some combinations resulting in higher resolution and image stability. The apparatus also eliminates a need for bulk optics to modulate a phase delay in a reference arm of the optical path. Images may be reconstructed using two spectrometers, where each is coupled to a detector array such as a photodiode array.
OSA | Real-time, high velocity-resolution color Doppler optical coherence tomography
Color Doppler optical coherence tomography (CDOCT) is a noninvasive optical imaging technique for micro-meter-scale physiological flow mapping simultaneously with morphological optical coherence tomography imaging. We have developed a novel CDOCT signal-processing strategy capable of imaging physiological flow rates at 8 frames/s. Our new strategy features hardware-implemented digital autocorrelation across subsequent scans, permitting us to measure 300-Hz-8-kHz Doppler shifts upon signals of 0.6-MHz bandwidth. The performance of the CDOCT system was demonstrated in a flow phantom and in vivo in Xenopus laevis.. © 2002 Optical Society of America. Full Article , PDF Article ...
Visual acuity and perimacular retinal layers detected by optical coherence tomography in patients with retinitis pigmentosa<...
TY - JOUR. T1 - Visual acuity and perimacular retinal layers detected by optical coherence tomography in patients with retinitis pigmentosa. AU - Matsuo, Toshihiko. AU - Morimoto, Noriko. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2007/7. Y1 - 2007/7. N2 - Background: The remaining retinal neurones or layered structure in the degenerating retina have been the prerequisite for epiretinal or subretinal retinal prostheses. Aim: To detect the layered structure in the eyes of patients with retinitis pigmentosa by optical coherence tomography. Methods: In a prospective non-comparative study, 115 eyes of 58 consecutive patients with retinitis pigmentosa underwent optical coherence tomography to obtain horizontal and vertical retinal cross-section images at the centre of the macula. The number of high-reflectance retinal layers, one, two or three layers, was tested to determine whether it correlates with best-corrected visual acuity. Results: The best-corrected visual ...
Optical Coherence Tomography: A review of current technology and its implications for clinical applications. |...
Christensen UC, KrÃ¸yer K, Sander B, Larsen M, la Cour M. Ophthalmology. 2009 Dec;116(12):2430-6. Christensen UC, KrÃ¸yer K, Sander B, Jorgensen TM, Larsen M, la Cour M.Macular morphology and visual acuity after macular hole surgery with or without internal limiting membrane peeling. Br J Ophthalmol. 2010 Jan;94(1):41-7 Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009 Sep;148(3):445-50. Hirata M, Tsujikawa A, Matsumoto A, Hangai M, Ooto S, Yamashiro K, Akiba M, Yoshimura N. Macular choroidal thickness and volume in normal subjects measured by swept-source optical coherence tomography. Invest Ophthalmol Vis Sci. 2011 Jul 1;52(8):4971-8 Marschall S, Sander B, Mogensen M, JÃ¸rgensen TM, Andersen PE. Optical coherence tomography-current technology and applications in clinical and biomedical research. Anal Bioanal Chem. 2011 Jul;400(9):2699-720. Sander B, Larsen M, Thrane L, ...
Longitudinal optical coherence tomography study of optic atrophy in secondary progressive multiple sclerosis: Results from a...
TY - JOUR. T1 - Longitudinal optical coherence tomography study of optic atrophy in secondary progressive multiple sclerosis. T2 - Results from a clinical trial cohort. AU - Winges, Kimberly. AU - Murchison, Charles F.. AU - Bourdette, Dennis. AU - Spain, Rebecca. PY - 2017/11/1. Y1 - 2017/11/1. N2 - Background: Limited prospective information exists regarding spectral-domain optical coherence tomography (SD-OCT) in secondary progressive multiple sclerosis (SPMS). Objective: Document cross-sectional and longitudinal retinal nerve fiber layer (RNFL) and macular ganglion cell plus inner plexiform layer (GCIPL) features of an SPMS clinical trial cohort. Methods: Prospective, observational study using a 2-year randomized placebo-controlled SPMS trial cohort with yearly SD-OCT testing. Post hoc analysis determined influences of optic neuritis (ON), disease duration, and baseline SD-OCT on annualized atrophy rates and on correlations between OCT and brain atrophy. Results: Mean RNFL and GCIPL values ...
Role of high resolution optical coherence tomography in diagnosing ocular surface squamous neoplasia with coexisting ocular...
TY - JOUR. T1 - Role of high resolution optical coherence tomography in diagnosing ocular surface squamous neoplasia with coexisting ocular surface diseases. AU - Atallah, Marwan. AU - Joag, Madhura. AU - Galor, Anat. AU - Amescua, Guillermo. AU - Nanji, Afshan. AU - Wang, Jianhua. AU - Perez, Victor L.. AU - Dubovy, Sander. AU - Karp, Carol L.. N1 - Funding Information: Supported by the NIH Center Core Grant P30EY014801 , RPB Unrestricted Award and Career Development Awards, Department of Defense (DOD- Grant# W81XWH-09-1-0675 ), Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences Research EPID-006-15S (Dr. Galor), The Ronald and Alicia Lepke Grant, The Lee and Claire Hager Grant, The Jimmy and Gaye Bryan Grant, The Azar Family Grant, The Robert Baer Family Grant, The Gordon Charitable Foundation, The H. Scott Huizenga Grant, The Grant and Diana Stanton-Thornbrough Grant, The Mark Feldberg Family Grant, and supported in part by an ...
Wavefront sensorless modal deformable mirror correction in adaptive optics: Optical coherence tomography<...
TY - JOUR. T1 - Wavefront sensorless modal deformable mirror correction in adaptive optics. T2 - Optical coherence tomography. AU - Bonora, S.. AU - Zawadzki, Robert. PY - 2013/11/15. Y1 - 2013/11/15. N2 - We present a method for optimization of optical coherence tomography images using wavefront sensorless adaptive optics. The method consists of systematic adjustment of the coefficients of a subset of the orthogonal Zernike bases and application of the resulting shapes to a deformable mirror, while optimizing using image sharpness as a merit function. We demonstrate that this technique can compensate for aberrations induced by trial lenses. Measurements of the point spread function before and after compensation demonstrate near diffraction limit imaging.. AB - We present a method for optimization of optical coherence tomography images using wavefront sensorless adaptive optics. The method consists of systematic adjustment of the coefficients of a subset of the orthogonal Zernike bases and ...
Flow measurement by using the signal decrease of moving scatterers in spatially encoded Fourier domain optical coherence...
Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD-OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. Therefore, we have numerically simulated the signal power decrease of an obliquely moved scattering layer as a function of the absolute sample velocity composed of an axial and transverse component. In contrast to the prevalent expectance, the resulting signal damping is not only the sum of axial and transverse effect. In this study, we take advantage of the signal decay and present the feasibility to quantify high flow velocities at which the standard Doppler OCT does not work any longer. For the validation of our approach, a flow phantom model consisting of a 1%-Intralipid solution and a 320 μm glass capillary was used. With this phantom study, depth-resolved flow was visualized and the quantitative velocities were extracted from the OCT images without phase information ...
Anterior segment optical coherence tomography to look for Kayser-Fleischer rings | Practical Neurology
Ophthalmologists usually use slit lamp biomicroscopy to look for Kayser-Fleischer rings in Wilsons disease; anterior segment optical coherence tomography is a new alternative to identify the characteristic hyper-reflective layer in the deep corneal periphery at the level of Descemets membrane. This method allows non-ophthalmologists to look for and to quantify Kayser-Fleischer rings. ...
Anterior Segment Optical Coherence Tomography eBook Kobo Edition | www.chapters.indigo.ca
Buy the Kobo ebook Book Anterior Segment Optical Coherence Tomography by at Indigo.ca, Canadas largest bookstore. Free shipping and pickup in store on eligible orders.
Optical Coherence Tomography Angiography in Choroideremia: Correlating Choriocapillaris Loss With Overlying Degeneration, JAMA...
Abstract Importance Novel therapies for choroideremia, an X-linked recessive chorioretinal degeneration, demand a better understanding of the primary site(s) of cellular degeneration. Optical coherence tomography angiography allows for choriocapillaris (CC) imaging. We compared the extent of structural alterations of the CC, retinal pigment epithelium, and photoreceptors with multimodal imaging. Observations In a clinical case series conducted from September 15, 2014, through February 5, 2015, 14 eyes of 7 male patients with choroideremia (median age, 34 years [interquartile range, 15-46 years]; age range, 13-48 years), 4 eyes of 2 women with choroideremia carrier state (both in mid-50s), and 6 eyes of 6 controls (median age, 42.5 years [interquartile range, 33-55 years]; age range, 24-55 years) underwent multimodal imaging with optical coherence tomography angiography and electroretinography. The mean (SD) macular CC density was 82.9% (13.4%) in patients with choroideremia, 93.0% (3.8%) in female
VASCULAR ALTERATIONS REVEALED WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH CHOROIDEREMIA. - Oxford...
PURPOSE: Choroideremia is a rare degenerative retinal disease that causes incurable blindness. It occurs as a result of the deficiency of the X-linked CHM gene, which encodes the Rab escort protein 1 (REP1). Gene therapy has been developed to treat CHM using adeno-associated viral vectors and is currently undergoing clinical trials. Expression of the CHM gene is ubiquitous throughout the retina, and it is therefore important to identify which retinal layers are affected in the disease process. The purpose of this study was to assess in particular the choriocapillaris using optical coherence tomography angiography because this layer is difficult to see with conventional imaging techniques. METHODS: Six men with choroideremia were identified and underwent standardized optical coherence tomography angiography as part of an ethics-approved clinical study and were compared with age-matched control subjects. RESULTS: The choriocapillaris appeared normal in regions where the retinal pigment epithelium remained
The Effect of Soft Contact Lenses During the Measurement of Retinal Nerve Fiber Layer Thickness Using Optical Coherence...
The Effect of Soft Contact Lenses During the Measurement of Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography
Efficacy of Retinal Nerve Fiber Layer (RNFL) / Retinal Thickness Ratio by Cirrus OCT Utilizing Spectral -Domain Technology as a...
Glaucoma is presumed to be an axonal disease which starts at the lamina cribrosa. This assumption has led to the monitoring of the retinal nerve fiber layer thickness for the diagnosis and monitoring of progression of glaucoma. However, varying disc size, myopia and tilted discs affect the thickness of the retinal nerve fiber layer. This study aims to ascertain the ration of the retinal nerve fiber layer against full retina as a predictor of glaucoma diagnosis and progression ...
Retinal nerve fibre layer and visual function loss in glaucoma: the tipping point
Aims To determine the retinal nerve fibre layer (RNFL) thickness at which visual field (VF) damage becomes detectable and associated with structural loss. Methods In a prospective cross-sectional study, 72 healthy and 40 glaucoma subjects (one eye per subject) recruited from an academic institution had VF examinations and spectral domain optical coherence tomography (SD-OCT) optic disc cube scans (Humphrey field analyser and Cirrus HD-OCT, respectively). Comparison of global mean and sectoral RNFL thicknesses with VF threshold values showed a plateau of threshold values at high RNFL thicknesses and a sharp decrease at lower RNFL thicknesses. A broken stick statistical model was fitted to global and sectoral data to estimate the RNFL thickness tipping point where the VF threshold values become associated with the structural measurements. The slope for the association between structure and function was computed for data above and below the tipping point. Results The mean RNFL thickness ...
Effect of refractive status on peripapillary retinal nerve fibre layer thickness: a study by RTVue spectral domain optical...
Results RNFL thickness values, except for lower and upper nasal sectors, were thinner in the myopic eyes than in the hyperopic eyes. Average RNFL thickness and the RNFL thicknesses of the superotemporal, superonasal, inferotemporal and lower temporal sectors were significantly different between the myopic and emmetropic eyes, and average RNFL thickness and the RNFL thicknesses of the upper temporal and inferonasal sectors were significantly different between the hyperopic and emmetropic eyes. The average peripapillary RNFL thickness had a negative correlation with axial length (r=−0.741, p,0.001). However, after correction of the magnification effect, the significant differences disappeared.. ...
Optical coherence tomography of patients with Parkinsons disease and progressive supranuclear palsy - Research Collection
Optical coherence tomography; Retinal nerve fiber layer thickness; Macular volume; Parkinson disease; PD; Progressive supranuclear palsy; ...
Optical Coherence Tomography | Vision Science and Advanced Retinal Imaging Laboratory
Optical coherence tomography (OCT) is an imaging modality analogous to ultrasound, but instead of using the difference in the flight times of acoustic waves (as in ultrasound), it uses light to achieve micrometer axial resolution. OCT is used in many different biomedical applications, with retinal imaging being the most successful and the driving force behind much OCT development. The axial resolution of OCT in retinal tissue is about 1-15 µm, which is 10 to 100 times better than ultrasound or MRI. Although relatively new to ophthalmology, a commercial OCT system has already revolutionized the field, rapidly becoming an essential tool in the diagnosis and monitoring of human retinal disease. As part of our collaboration with the Biomedical Engineering Department at Duke University, our group at the Vision Science and Advanced Retinal Imaging Laboratory has developed a Fourier-domain OCT system that is faster and has higher resolution than existing commercial OCT instruments. In collaboration ...
To Study the correlation between fundus fluorescein angiography and optical coherence tomography patterns in clinically...
To Study the correlation between fundus fluorescein angiography and optical coherence tomography patterns in clinically significant macular oedema
Validation of a Novel Automated Algorithm to Measure Drusen Volume and Area Using Swept Source Optical Coherence Tomography...
Generally, the measurements for the drusen area and volume from SS-OCTA were larger than those from SD-OCT. In the center 3 mm circle, the mean drusen area measurements were 1.52 mm2 and 2.11 mm2 from the SD-OCT and SS-OCTA scans, respectively, and the mean square root of the drusen area measurements were 1.17 mm and 1.39 mm from the SD-OCT and SS-OCTA scans, respectively. In the 5 mm circle, the mean drusen area measurements were 1.89 mm2 and 2.67 mm2 from the SD-OCT and SS-OCTA scans, respectively, and the mean square root of drusen area measurements were 1.28 mm and 1.54 mm from the SD-OCT and SS-OCTA scans, respectively. Similarly, the cube root drusen volumes were larger from the SS-OCTA scans. In the center 3 mm circle, the mean drusen volume measurements were 0.09 mm3 and 0.13 mm3 from the SD-OCT and SS-OCTA scans, respectively, and the mean cube root of drusen volume measurements were 0.41 mm and 0.47 mm from the SD-OCT and SS-OCTA scans, respectively. In the center 5 mm circle, the mean ...
Optical coherence tomography characteristics of full-thickness traumatic macular holes
Purpose the objective of this paper is to describe the optical coherence tomography (OCT) characteristics of patients with full-thickness traumatic macular hole (TMH) and to correlate them with biomicroscopy findings.Methods Twelve eyes of ten consecutive patients with full-thickness TMH participated in this observational retrospective multicentre study. Patients underwent biomicroscopic fundus examination, colour fundus photography, and OCT.Results Traumatic macular hole was documented with OCT in five women and five men. Mean (range) time between trauma and macular hole (MH) diagnosis was 8.1 (1-24) months. the shape of TMHs was round in 11 (91.7%) eyes. the posterior vitreous was completely detached in six (50%) eyes, and with an operculum in one (8.3%) eye. the common findings seen on OCT were: (1) full-thickness loss of retinal tissue through the hole with sharp edges, perpendicular to the retinal pigment epithelium in five (41.7%) eyes; (2) TMH with an operculum totally detached from the ...
EyetubeOD - Understanding and Interpreting Optical Coherence Tomography
Mark Dunbar, OD, discusses his recent lecture on optical coherence tomography (OCT) technology. He highlights the increasing need to have OCT in an optometry office, emphasizing its importance for diagnosing vitreomacular disease as well as glaucoma.
גלאוקומה וקטרקט, פרופ איתן בלומנטל | Quantifying Retinal Nerve Fiber Layer Thickness Histologically: A Novel Approach To...
PURPOSE: To present a technique of ocular sectioning that enables continuous histologic measurements of peripapillary retinal nerve fiber layer (RNFL) thickness in a concentric ring around the optic disc, corresponding to similar regions measured by in vivo imaging techniques.. METHODS: Two pig eyes and two normal human eyes were processed using the umbrella technique, in which peripapillary concentric ring sections were obtained, at increasing diameters, all centered on the optic disc. Each histologic ring section contains a continuous circumferential 360 degrees retinal slice, oriented approximately perpendicular to the retinal surface. Every histologic slice contains each axon of the retina, sectioned perpendicular to each axons long axis and at an equal set distance from the disc margin.. RESULTS: Ring sections from pig and human eyes are presented and correlated to known RNFL anatomy. For the two human eyes, peripapillary RNFL thickness was quantified and plotted, resulting in the ...
Choroidal vascular changes in retinitis pigmentosa patients detected by optical coherence tomography angiography | BMC...
To evaluate choroidal vascular changes, including choriocapillaris (CC) and middle/large choroidal vessels, in retinitis pigmentosa (RP) patients using wide-angle optical coherence tomography angiography (OCTA) and to determine whether changes in the choroidal vascularity have a relationship with visual function and retinal structural changes. 34 patients with a confirmed diagnosis of RP and 48 controls were recruited. All patients underwent detailed ophthalmologic and imaging examinations, including two types of OCTA (Optovue, 3 × 3 mm, 6 × 6 mm; VG-200, 12 × 12 mm). CC defects were defined according to the choroidal vascular structure in five degrees. To evaluate middle and large choroidal vascular changes, the choroidal vascularity index (CVI), which was the luminance volume to the total choroidal volume, was used. Defects of choroidal vascularity of RP eyes were detected in comparison to control eyes. The defects were observed in the CC layer with a concentric or lobular pattern at different
IDIOPATHIC AND SECONDARY EPIRETINAL MEMBRANES Do They Differ in Terms of Morphology? An Optical Coherence Tomography-Based...
Purpose: The purpose of this study was to define the morphologic differences in idiopathic and secondary epiretinal membranes (ERMs) using a time domain optical coherence tomography. ...
Ear Canal Optical Coherence Tomography System - Paul Shnitser
The National Institute on Deafness and Other Communication Disorders (NIDCD) supports research and development of innovative technologies for improving the qual...
Full text] Relative sensitivity and specificity of 10-2 visual fields, multifocal | OPTH
Relative sensitivity and specificity of 10-2 visual fields, multifocal electroretinography, and spectral domain optical coherence tomography in detecting hydroxychloroquine and chloroquine retinopathy David J Browning, Chong Lee Charlotte Eye, Ear, Nose and Throat Associates, Charlotte, NC, USA Background: The purpose of this study was to determine the relative sensitivity and specificity of 10-2 visual fields (10-2 VFs), multifocal electroretinography (mfERG), and spectral domain optical coherence tomography (SD-OCT) in detecting hydroxychloroquine retinopathy.Methods: A total of 121 patients taking hydroxychloroquine (n=119) or chloroquine (n=2) with 10-2 VF, mfERG, and SD-OCT tests were retrospectively reviewed. Rates of test abnormality were determined.Results: Retinopathy was present in 14 and absent in 107. Eleven of 14 (78.6%) patients with retinopathy were overdosed. Twelve (85.7%) had cumulative dosing greater than 1,000 g. The sensitivities of 10-2 VF, mfERG, and SD-OCT in detecting
Scanning laser ophthalmoscopy
Optical coherence tomography. Spie Milestone Series MS. 1998;147:324-7. Romero-Borja F, Venkateswaran K, Roorda A, Hebert T. " ... Optical coherence tomography (OCT) represents a powerful clinical tool for monitoring retinal physiology in patients. OCT uses ... "Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema ... with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography". ...
He is known for his leading role in the invention of a novel medical imaging modality named optical coherence tomography that ... Boyd, Kierstan (14 October 2015). "What Is Optical Coherence Tomography?". American Academy of Ophthalmology. Retrieved 8 ... Optical coherence tomography, Fellows of the American Physical Society, Fellows of the American Association for the Advancement ... "Optical Coherence Tomography". Science. 254 (5035): 1178-1181. doi:10.1126/science.1957169. PMC 4638169. PMID 1957169. ...
Joel S. Schuman
"Articles that mention Joel S. Schuman". Optical Coherence Tomography News. Retrieved 2015-08-29. "Sight + Sound" (PDF). ... invented the optical coherence tomography (OCT) technology. This technology, allows a quick and noninvasive 3D map of the eye, ...
1991). "Optical Coherence Tomography" (PDF). Science. 254 (5035): 1178-81. Bibcode:1991Sci...254.1178H. doi:10.1126/science. ... Another application of the Michelson interferometer is in optical coherence tomography (OCT), a medical imaging technique using ... Fercher, A.F. (1996). "Optical Coherence Tomography" (PDF). Journal of Biomedical Optics. 1 (2): 157-173. Bibcode:1996JBO.....1 ... exceeds coherence length of light beams. The nontrivial features of phase fluctuations in optical phase-conjugating mirror had ...
Malvin Carl Teich
Quantum optical coherence tomography (QOCT). Entangled-photon ellipsometry. Entangled-photon cryptography. Entangled-photon ... "Variations on the Theme of Quantum Optical Coherence Tomography: A Review" (PDF). Quantum Information Processing. 11 (4): 903- ... Quantum Photonics: Optical heterodyne detection. Photon statistics and point processes. Single-photon detection at the retinal ... 19, Optical and Infrared Detectors (Second ed.). Berlin: Springer. pp. 229-300. ISBN 9783540707547. Retrieved 10 October 2021. ...
St. Jude Medical
In 2010 the company also acquired LightLab Imaging, a company that developed optical coherence tomography technology that helps ... The device uses fractional flow reserve for measuring intra-arterial pressure and optical coherence tomography technology, ... optical coherence tomography (OCT) imaging systems; structural heart repair products; and neurostimulation devices. The ...
Giovanni J. Ughi
"winner of Optical Coherence Tomography Award". 9 January 2011. Retrieved 11 September 2016. "Giovanni J. Ughi, PhD". Google ... is one of the inventors of multimodality Optical Coherence Tomography (OCT) and Laser-induced fluorescence molecular imaging, ... "Automatic segmentation of in-vivo intra-coronary optical coherence tomography images to assess stent strut apposition and ... "Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in ...
"NASA - Optical Coherence Tomography Technology Demonstration". www.nasa.gov. Retrieved 2018-10-13. "What's Next for Twins Study ... She has since been studying Spaceflight-Associated Neuro-Ocular Syndrome, and sent an optical coherence tomography scanner up ...
Audrey Ellerbee Bowden
She completed her Ph.D. in biomedical engineering at Duke University in 2007, specialising in optical coherence tomography. Her ... Her research group develops new imaging devices and techniques based on optical coherence tomography, and developing point-of- ... Ellerbee, Audrey K. (2014-10-01). "Optical coherence tomography: Technology and applications". 2014 IEEE Photonics Conference: ... Her research in biomedical optics focuses on developing new imaging techniques and devices for optical coherence tomography and ...
Pathology of multiple sclerosis
MS patients show axonal loss in the retina and optic nerve, which can be measured by Optical coherence tomography or by ... 2007). "Optical coherence tomography and disease subtype in multiple sclerosis". Neurology. 69 (22): 2085-2092. doi:10.1093/ ... March 2009). "Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis". Neurology. 72 (12 ... Evangelou, Nikos; Alrawashdeh, Omar S. M (2016). "Anatomy of the Retina and the Optic Nerve". Optical Coherence Tomography in ...
"Ultrahigh-resolution full-field optical coherence tomography". Applied Optics. 43 (14): 2874-2883. Bibcode:2004ApOpt..43.2874D ... The advantage of this design its ability to compensate for chromatic dispersion and other optical aberrations. In the image of ...
Abazari, Azin; Allam, Souha S.; Adamus, Grazyna; Ghazi, Nicola G. (2016-11-21). "Optical Coherence Tomography Findings in ...
Fractional flow reserve Intracoronary Optical Coherence Tomography Hector M. Garcia-Garcia, Bill D. Gogas, Patrick W. Serruys ... "Intracoronary Optical Coherence Tomography: A Comprehensive Review". JACC: Cardiovascular Interventions. 2 (11): 1035-1046. doi ...
Strait of Juan de Fuca laser incident
Findings from optical coherence tomography were normal. Amsler grid test results were highly variable, and the locations of ...
The optical contrast of gas vesicles also enables them to serve as contrast agents in optical coherence tomography, with ... "Biomolecular Contrast Agents for Optical Coherence Tomography" (PDF). bioRxiv. doi:10.1101/595157. S2CID 133072739. Shapiro MG ...
Stephen A. Boppart
... where he has pioneered new optical imaging technologies in the fields of optical coherence tomography, multi-photon microscopy ... "CAREER: Functional Optical Coherence Tomography for Neural Imaging". www.nsf.gov. Retrieved 2017-12-12. "Hans Sigrist Prize ... 2011). "Handheld Optical Coherence Tomography Scanner for Primary Care Diagnostics". IEEE Trans. Biomed. Eng. 58 (3): 741-744. ... While at MIT, he was involved in the invention and early development of optical coherence tomography (OCT). Boppart started the ...
Using optical coherence tomography (OCT), 18 layers can be identified in the retina. The layers and anatomical correlation are ... A relatively new technology, now becoming widely available, is optical coherence tomography (OCT). This non-invasive technique ... Meyer, Carsten H.; Saxena, Sandeep; Sadda, Srinivas R. (2017). Spectral domain optical coherence tomography in macular diseases ... "Past and Present Terminology for the Retinal and Choroidal Structures in Optical Coherence Tomography". European Ophthalmic ...
... optical coherence tomography can offer unique benefits. Optical coherence tomography angiography can help the physician see if ... Fundus autofluorescence and optical coherence tomography angiography are imaging modalities that can be used in the diagnosis. ... "Optical Coherence Tomography in Age-related Macular Degeneration". AMD book. Retrieved 8 December 2019. Malciolu Radu Alexandru ... These more subtle changes can be quantified by volumetric analyses of optical coherence tomography data. There are currently no ...
"Occult Hypotony Maculopathy Diagnosed With Optical Coherence Tomography". Archives of Ophthalmology. 123 (1): 113-114. doi: ...
Health effects of sunlight exposure
Chen JC, Lee LR (2004). "Solar retinopathy and associated optical coherence tomography findings". Clin Exp Optom. 87 (6): 390- ... Prolonged optical exposure to sunlight, especially intense ultraviolet light, may be linked to cortical cataracts, and high ...
High-speed optical coherence tomography of corneal opacities. Ophthalmology. 2007 Jul;114(7):1278-85. Plesea et al. Direct ... OCT Biomicroscopy is the use of optical coherence tomography (OCT) in place of slit lamp biomicroscopy to examine the ... Keratoconus diagnosis with optical coherence tomography pachymetry mapping. Ophthalmology 2008 Dec;115(12):2159-66. Eye ... Detailed visualization of the anterior segment using fourier-domain optical coherence tomography. Arch Ophthalmol 2008 June;126 ...
"Solar retinopathy and associated optical coherence tomography findings." Archived 2006-09-27 at the Wayback Machine Clin Exp ...
Christine P. Hendon
Optical Coherence Tomography: A Novel Imaging Method for Post-lumpectomy Breast Margin Assessment-A Multi-reader Study. Acad ... 2007). Ultrahigh-resolution optical coherence tomography at 1.15 μm using photonic crystal fiber with no zero-dispersion ... An automated 3D registration method for optical coherence tomography volumes. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3873‐ ... Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector. Biomed Opt Express ...
There is insufficient evidence that optical coherence tomography (OCT) is useful in diagnosing melanoma or squamous cell ... Cochrane Skin Group) (December 2018). "Optical coherence tomography for diagnosing skin cancer in adults". The Cochrane ... optical coherence tomography, the multispectral imaging technique, thermography, electrical bio-impedance, tape stripping and ...
"Optical Coherence Tomography: What It Is & How It's Used". Cleveland Clinic. Retrieved 2022-07-25. "Foveal Hypoplasia 2 , ... Today, a newer technology, optical coherence tomography (OCT) is used to detect foveal hypoplasia and does not require a dye. ... Recchia, Franco M.; Carvalho-Recchia, Cynthia A.; Trese, Michael T. (2002-11-01). "Optical Coherence Tomography in the ...
Chen JC, Lee LR (November 2004). "Solar retinopathy and associated optical coherence tomography findings" (PDF). Clin Exp Optom ...
Some of these locations use a fundus camera, others use both fundus and optical coherence tomography (OCT) imaging devices, and ... "Teleophthalmology with optical coherence tomography imaging in the community". Clinical Ophthalmology. 5: 1673-1678. 2011. ... Recently, emerging retinal imaging modalities such as optical coherence tomography are capable of producing digital images of ... Kelly, SP; I Wallwork; D Haider; K Qureshi (2011). "Teleophthalmology with optical coherence tomography imaging in community ...
Ah-kee, Elliott; Oladiwura, Dilys; Lim, Lik Thai; Scott, Angus (2014-05-19). "Macular optical coherence tomography findings ...
Optical coherence tomography is frequently used to assess macular edema. Fluorescein angiography is used by retina specialists ... Optical coherence tomography (OCT) is used to determine the severity of edema and treatment response. Because fundoscopic ...
... s have proven useful in a wide variety of applications including optical coherence tomography, ... "Common-path interferometer for frequency-domain optical coherence tomography" (PDF). Applied Optics. 42 (34): 6953-6957. ... both of which interfere with the optical measurements. Precision measurements of an optical surface are also extremely ... It usually consists of a beam splitter, an optical flat, a biconvex diverger of short focal length and a light source such as a ...
അസ്റ്റിഗ്മാറ്റിസം - വിക്കിപീഡിയ
Optical coherence tomography. *നേത്ര സംരക്ഷണ വിദഗ്ദ്ധർ. *നേത്ര രോഗങ്ങൾ. *അപവർത്തന ദോഷം. *അക്കൊമഡേഷൻ ...
Optical coherence tomography (OCT) is a medical technological platform used to assess ocular structures. The information is ... The origins of optical science (optics, as taught in a basic physics class) date back a few thousand years as evidence of the ... "Free NHS eye tests and optical vouchers". NHS. 14 August 2018.. *^ Agarwal, R. (2008), Integrating theory with practice, ... They provide optical and medical eye care. They are able to diagnose and treat most eye diseases and can prescribe both topical ...
Optical coherence tomography. *Electrodiagnosis: Electrooculography. *Electroretinography. *Electronystagmography. Eye ...
Medical optical imaging
Ballistic scanners (using ultrafast time gates) and optical coherence tomography (OCT) (using the interferometry principle) are ... The technique may also be referred to as diffuse optical tomography (DOT), near infrared optical tomography (NIROT) or ... and optical coherence tomography. Because light is an electromagnetic wave, similar phenomena occur in X-rays, microwaves, and ... Diffusive optical imaging. Diffuse optical imaging (DOI) is a method of imaging using near-infrared spectroscopy (NIRS) [ ...
Optical/Laser. *Optical tomography *Optical coherence tomography. *Confocal microscopy. *Endomicroscopy. *Orthogonal ... In contrast, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate ... Detectors coated with materials which scintillate when subjected to gamma rays are scanned with optical photon detectors and ... A special type of gamma camera is the SPECT (Single Photon Emission Computed Tomography). Another medical scintillography ...
Эпигенетические часы - Википедия
... associated with accelerated eye aging by using deep learning to predict age from fundus and optical coherence tomography images ...
ഗ്യാസ് ലേസർ - വിക്കിപീഡിയ
Optical coherence tomography. *Photorefractive keratectomy. *Photorejuvenation. *Soft-tissue laser surgery. Laser fusion. * ...
Macula of retina
Optical coherence tomography. *Eye care professional. *Eye disease. *Refractive error. *Accommodation. *Physiological Optics ... Validity of the Ferry-Porter law". Journal of the Optical Society of America A. 7 (4): 743-758. Bibcode:1990JOSAA...7..743T. ... Its center is shifted slightly away from the optical axis (laterally, by 5°=1.5 mm). The macula in humans has a diameter of ...
Other gastroscopic modalities such as optical coherence tomography are being tested investigationally for similar applications. ... Computed tomography or CT scanning of the abdomen may reveal gastric cancer. It is more useful to determine invasion into ...
Optical coherence tomography. *Eye care professional. *Eye disease. *Refractive error. *Accommodation. *Physiological Optics ... Of course, for most eye types, it is impossible to diverge from a spherical form, so only the density of optical receptors can ... Land, M.F. (1989). "The eyes of hyperiid amphipods: relations of optical structure to depth". Journal of Comparative Physiology ... This occurs because the ommatidia which one observes "head-on" (along their optical axes) absorb the incident light, while ...
Photonic integrated circuit
"Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated ... It was included by the Optical Internetworking Forum for inclusion in 100 gigahertz optical networking standards. Optical ... The range of devices required on a chip includes low loss interconnect waveguides, power splitters, optical amplifiers, optical ... For instance, EFFECT Photonics develops affordable and high-performance optical communications solutions, such as SPF+ optical ...
Directional atherectomy is an intravascular procedure guided by optical coherence tomography termed as lumivascular atherectomy ...
Optical measurements of Ca2+ concentration showed that they respond strongly to the centrifugal motion (the outward motion from ... The sensitivity to motion coherence is assessed by measuring the ratio of 'signal' to 'noise' dots required to determine the ... 1993). "Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance ... The required ratio is called the motion coherence threshold. As in other aspects of vision, the observer's visual input is ...
Layton Rahmatullah Benevolent Trust
Optical Coherence Tomography, Field Analysis etc. Glaucoma Lacrimal (Tear Duct) Disorder Laser treatment Oculo-plastic Services ...
Index of physics articles (C)
Coherence (physics) Coherence length Coherence theory (optics) Coherence time Coherent backscattering Coherent control Coherent ... Chaos in optical systems Chaos theory Chaotic Inflation theory Chaplygin gas Chapman function Chapman-Enskog theory Chapman- ... Conductivity of transparency Conductor gallop Cone beam computed tomography Configuration interaction Configuration space ... optical fiber) Core electron Core-mantle boundary Coriolis effect Coriolis field Coriolis-Stokes force Corium (nuclear reactor ...
"Signal attenuation and box-counting fractal analysis of optical coherence tomography images of arterial tissue". Biomedical ...
The retinal nerve fiber layer can be assessed with imaging techniques such as optical coherence tomography, scanning laser ... 12 (9). Aptel F, Dumas S, Denis P (2009). "Ultrasound biomicroscopy and optical coherence tomography imaging of filtering blebs ...
... facilitating control of color using optical coherence tomography. Structural control means that a single fiber will always show ... The ability to vary reflectivity to different wavelengths of light could also lead to efficient optical switches that could ... efficient optical switches and low-reflectance glass. In his 1665 book Micrographia, Robert Hooke described the "fantastical" ... or they are partly caused by optical effects due to the scattering, diffraction or unequal refraction of the light rays. ...
Ballistic scanners (using ultrafast time gates) and optical coherence tomography (OCT) (using the interferometry principle) are ... Medical optical imaging Lihong V. Wang; Hsin-i Wu (26 September 2012). Biomedical Optics: Principles and Imaging. John Wiley & ... Photons that are slightly scattered, retaining some degree of coherence, are referred to as snake photons. The aim of ballistic ... non-ballistic photons are used, such as time of flight through coherence-gated imaging, collimation, wavefront propagation, and ...
4D scanning transmission electron microscopy
Treacy, M. M. J.; Gibson, J. M. (1996-03-01). "Variable Coherence Microscopy: a Rich Source of Structural Information from ... Lee, Z.; Kaiser, U.; Rose, H. (January 2019). "Prospects of annular differential phase contrast applied for optical sectioning ... Eggeman, Alexander S.; Krakow, Robert; Midgley, Paul A. (2015-06-01). "Scanning precession electron tomography for three- ...
"Performance and scalability of Fourier domain optical coherence tomography acceleration using graphics processing units". ... "Performance and scalability of Fourier domain optical coherence tomography acceleration using graphics processing units". ...
Free electron laser Laser hair removal IPL Photobiomodulation Optical diagnostics, for example optical coherence tomography of ... optical diagnostics, cardiology, circadian rhythm sleep disorders and oncology. A branch of photomedicine is light therapy in ...
Hypotrichosis with juvenile macular dystrophy
Fluorescent angiogram of a 5-year-old boy with HJMD Optical coherence tomography of a 5-year-old boy with HJMD Fundoscopy, left ... retinal scanning and optical coherence tomography; electrophysiological examinations such as electroretinography (ERG) or ...
Potential applications of graphene
... in vivo imaging of cortical vasculature via fluorescence microscopy and 3D optical coherence tomography. Researchers at Monash ... "Optical antennas trap and control light with the help of graphene". May 23, 2014. Ren, Xingang; Sha, Wei E. I.; Choy, Wallace C ... Optical transparency was greater than 90%. Applications demonstrated include optogenetic activation of focal cortical areas, ... Szondy, David (January 31, 2016). "Graphene optical lens a billionth of a meter thick breaks the diffraction limit". newatlas. ...
Proscurin, Sergei; Meglinski, Igor (2007). "Optical coherence tomography imaging depth enhancement by superficial skin optical ... Meglinski, Igor; Buranachai, Chitannon; Terry, Leon (2010). "Plant Photonics: Use of Optical Coherence Tomography to monitor ... pioneering the enhancement of probing depth for confocal reflectance microscopy and Optical Coherence Tomography (OCT). This ... Fellows of the Optical Society, Fellows of SPIE, Fellows of the Institute of Physics, Senior Members of the IEEE, Optical ...
Multiple scattering low coherence interferometry
"Balanced detection for spectral domain optical coherence tomography". Optics Express. 21 (16): 19280-19291. doi:10.1364/OE. ... to the specularly reflected light that is assessed in more conventional imaging methods such as optical coherence tomography. ... Multiple scattering low coherence interferometry (ms/LCI) is an imaging technique that relies on analyzing multiply scattered ... As in traditional OCT, the beam interference coherence gates the light in order to filter out photons that have not traveled a ...
Oral and maxillofacial radiology
Other modalities, including optical coherence tomography are also under development for dental imaging. Oral or dental ... Machoy M, Seeliger J, Szyszka-Sommerfeld L, Koprowski R, Gedrange T, Woźniak K (2017). "The Use of Optical Coherence Tomography ... Oral and maxillofacial imaging includes cone beam computerized tomography, multislice computerized tomography, magnetic ... cone beam computerized tomography, multislice computerized tomography and magnetic resonance imaging of the maxillofacial ...
"Optical coherence tomography using a continuous-wave, high-power, Raman continuum light source". Optics Express. The Optical ... "Ultrahigh-resolution optical coherence tomography using continuum generation in an air-silica microstructure optical fiber". ... including optical coherence tomography, frequency metrology, fluorescence lifetime imaging, optical communications, gas sensing ... Schnatz, H.; Hollberg, L.W. (2003). "Optical frequency combs: From frequency metrology to optical phase control". IEEE Journal ...
... of Cystoid Macular Edema after Cataract Surgery in Patients with and without Uveitis Using Optical Coherence Tomography". ...
With his work he has made significant contributions to development of the Optical Coherence Tomography (OCT) method and ... "Real-time in vivo imaging by high-speed spectral optical coherence tomography". Opt. Express. 28 (19): 1745-1747. Bibcode: ... Wojtkowski is a Fellow of the Optical Society of America, and since 2016 he is a corresponding member of the Polish Academy of ... which he later led until 2016 as the Optical Biomedical Imaging Group. After succeeding in the 2015 EraChair competition, ...
The Use of Optical Coherence Tomography in Neurology
Review the basic principles of optical coherence tomography and its application in a variety of neurological disorders, ... Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-resolution in vivo imaging of ... Optical coherence tomography (OCT) is an efficient, non-invasive imaging modality that utilizes light interferometry to ... In this review, we outline the basic principles of optical coherence tomography and discuss its application to managing ...
Optical Coherence Tomography - Michigan College Of Optometry
The OCT is the first instrument that allows doctors to see a direct cross-sectional image of the retina. The OCT is similar to a CT scan of internal organs, except it doesnt use X-rays. Instead a beam of light is used to rapidly scan the eye and generate an image without ever touching the patient. This painless scan takes less than 10 minutes. Since there is no patient contact, patient comfort is improved and the test is performed in less time. These images are critical to assess the anatomical structures of the eye and any retinal changes.. This scan can provide practitioners with a guidepost to determine how a specific patient s retinal nerve fiber layer compares to a normal range on the instruments database. Therefore, changes in the thickness of the retinal nerve fiber layer could be an indication of early glaucomatous changes. Besides glaucoma, the OCT analysis the appearance of various changes in the posterior segment of the eye. These include diabetic retinopathy, macular holes, ...
Evaluation of age-related macular degeneration with optical coherence tomography
Real-time high-resolution mid-infrared optical coherence tomography | Light: Science & Applications
... the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical ... In this work, a mid-infrared spectral-domain optical coherence tomography system operating at a central wavelength of 4 µm and ... In doing so, the first practical mid-infrared optical coherence tomography system is demonstrated, with immediate applications ... Using longer wavelengths of light in Optical Coherence Tomography (OCT) imaging allows deeper penetration in highly scattering ...
Relationship Between Optical Coherence Tomography and Anteri... : Journal of Glaucoma
Patterns of Optical Coherence Tomography Imaging in Preperimetric Open Angle Glaucoma: A Comparative Study With Young-Age-Onset ... optical coherence tomography (OCT)\r, primary angle closure suspect (PACS)\r, anterior chamber depth (ACD)\r, intraocular ... Relationship Between Optical Coherence Tomography and Anterior Chamber Depth After Pupillary Dilation in Primary Angle Closure ... Relationship Between Optical Coherence Tomography and Anterior Chamber Depth After Pupillary Dilation in Primary Angle Closure ...
Full-Field Optical Coherence Tomography - Fraunhofer IPT
Full-Field Optical Coherence Tomography (FF-OCT or Full-Field OCT) is ideally suited for the in vitro examination of tissue ... Measurement systems for optical coherence tomography (OCT) therefore offer great diagnostic added value due to their high ... www.ipt.fraunhofer.de/en/Competencies/Productionqualityandmetrology/Productionmetrology/full-field-optical-coherence-tomography ... Fraunhofer Institute for Production Technology IPT - Full-Field Optical Coherence Tomography. Online in Internet; URL: https:// ...
Affordable Optical Coherence Tomography (OCT) Imaging System Provides High Resolution Imaging | Lab Manager
Affordable Optical Coherence Tomography (OCT) Imaging System Provides High Resolution Imaging. Features axial resolutions of ... introduces a new Optical Coherence Tomography (OCT) Imaging System from Lumedica, the OQ LabScope. This all-in-one, high ... December 14, 2017, Barrington, N.J. - Edmund Optics® (EO), the premier provider of optical components, ... has earned it the position of the worlds largest supplier of off-the-shelf optical components. Customers can purchase items by ...
Optics for Optical Coherence Tomography (OCT) | Edmund Optics
Optics for Optical Coherence Tomography (OCT). ON DEMAND WEBINAR. See All Webinars ... Adam Wax, Founder of Lumedica, for our next webinar on Optical Coherence Tomography (OCT). Topics discussed will include: an ... He is a fellow of the Optical Society of America, SPIE, and AIMBE and is inventor on 19 US patents. He currently serves as the ... Join us for a demonstration on selecting the proper optical components for your OCT system for non-invasive, high-resolution ...
Optical Coherence Tomography Angiography in Herpetic Leucoma | Research Square
This study instends to investigate the potential of Optical Coherence Tomography Angiography (OCTA) device to image and ... Optical Coherence Tomography Angiography; VD: Vessel Density; CoNV: Corneal Neovascularization; OCT: Optical Coherence ... Optical coherence tomography angiography: a review of current and future clinical applications. Graefes Arch Clin Exp ... Comparison of Optical Coherence Tomography Angiography to Indocyanine Green Angiography and Slit Lamp Photography for Corneal ...
Optical Coherence Tomography | TOPTICA Photonics AG
Publications: Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography, OCT NEWS, Feature of the ... Publications: Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography, Optics Express, 2010, 18(10 ... Synchronized Femtosecond Fiber Lasers for Optical Coherence Tomography (OCT) Using ECOPS to speed up TD-OCT measurements OCT ... Publications: Optical Coherence Tomography with fs Fiber Lasers and ECOPS, Laser Magazin, 2009, 2-3, pp. 62-94. ...
3D thickness measurement using pulse-driven optical coherence tomography based on wavelet transform | (2019) | Suzuki | ...
3D thickness measurement using pulse-driven optical coherence tomography based on wavelet transform Author(s): Takamasa Suzuki ... In this study, we propose a spectral-domain optical coherence tomography (OCT) method that employs pulse irradiation to capture ... SPIE 11102, Applied Optical Metrology III, 111021A (3 September 2019); doi: 10.1117/12.2534005. Show Author Affiliations. ...
Diagnostic Accuracy of Endobronchial Optical Coherence Tomography for the Microscopic Diagnosis of Usual Interstitial Pneumonia...
Optical Coherence Tomography (OCT)
... be alluded to as diffuse optical tomography close to infrared optical tomography or fluorescence diffuse optical tomography, ... Ballistic scanners utilizing ultrafast time entryways and optical intelligence tomography utilizing the interferometry ... and optical rationality tomography. Since light is an electromagnetic wave, comparative marvels happen in Xbeams, microwaves, ... Clinical optical imaging is the utilization of light as an investigational imaging strategy for clinical applications. Models ...
Optical Coherence Tomography: Market Insights, Growth & Forecast 2024
Global optical coherence tomography market is projected to account for noteworthy sales of USD 1.8 Billion by 2024. ... Optical Coherence Tomography Market Overview. Optical coherence tomography is referred to a non-invasive imaging diagnostic ... Time domain Optical Coherence Tomography (TDOCT). *Spatially Encoded Frequency Domain Optical Coherence Tomography *Spectral ... However, high cost of optical coherence tomography is expected to hinder the growth of optical coherence tomography market ...
System and method for measuring internal dimensions of an object by optical coherence tomography - Patent EP-2675338-B1 -...
En face swept-source optical coherence tomography in neovascular age-related macular degeneration | British Journal of...
Purpose To describe en face swept-source optical coherence tomography (SS-OCT) findings in the retinal pigment epithelium (RPE ... En face swept-source optical coherence tomography in neovascular age-related macular degeneration ... En face swept-source optical coherence tomography in neovascular age-related macular degeneration ...
Phase estimation for global defocus correction in optical coherence tomography<...
International Society for Optical Engineering, 2nd Canterbury Conference on Optical Coherence Tomography, Canterbury, United ... Phase estimation for global defocus correction in optical coherence tomography. Mikkel Jensen, Niels Møller Israelsen, Adrian ... Phase estimation for global defocus correction in optical coherence tomography. Mikkel Jensen (Speaker), Niels Møller Israelsen ... keywords = "Optical coherence tomography, Angular spectrum method, Defocus correction",. author = "Mikkel Jensen and Israelsen ...
Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography - Lancaster EPrints
Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical ... Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. Journal of Pharmaceutical Sciences, 106 ... As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some ...
Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or...
Enhanced depth imaging optical coherence tomography (EDI-OCT), Heterogeneous uveitis, Hyper-reflective foci, Hypo-reflective ... PURPOSE: Enhanced depth imaging (EDI) optical coherence tomography (OCT) has emerged as a novel tool for qualitative and ... Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or ... Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or ...
Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography. -...
As SOCM constitutes the microscopy counterpart to spectral optical coherence tomography (SOCT), the developed processing ... present an application of massively parallel processing of quantitative flow measurements data acquired using spectral optical ... coherence microscopy (SOCM). The need for massive signal processing of these particular datasets has been a major hurdle for ... Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography.. ...
Evaluation of Contrast Agents for Enhanced Visualization in Optical Coherence Tomography | IOVS | ARVO Journals
Molecular optical coherence tomography contrast enhancement and imaging. In: Drexler W Fujimoto JG eds. Optical Coherence ... Evaluation of Contrast Agents for Enhanced Visualization in Optical Coherence Tomography Justis P. Ehlers; Preeya K. Gupta; ... time domain optical coherence tomography. Opt Express. 2003;11:889-894. [CrossRef] [PubMed] ... Huang D Swanson EA Lin CP . Optical coherence tomography. Science. 1991;254:1178-1181. [CrossRef] [PubMed] ...
Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. |...
Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. ... Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. Journal ... Optical coherence tomography (OCT) is a depth-resolved, noninvasive, non-destructive imaging modality, the use of which has yet ... The optical and histological results showing cardiovascular microstructures such as myocardium, the cardiac jelly, and ...
Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography...
Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography ... Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography ... a case of live intravitreal cysticercosis with a FTMH along with its management and intraoperative optical coherence tomography ...
Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence...
... applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired ... applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired ... circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography. ...
Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography - Strathprints
Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography ... This study demonstrates the use of optical coherence tomography (OCT) to simultaneously characterize the roughness of the ... 3D thickness map, coating, optical coherence tomography, roughness, solid oral dosage form, Pharmacy and materia medica, ... Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography. International Journal of ...
Optical coherence tomography used in process monitoring of AM
... Process monitoring in the Additive Manufacturing process has ... Optical coherence tomography (OCT) has been utilised for in-line monitoring, with analysis of surfaces as well as internal ... Optical coherence tomography used in process monitoring of Additive Manufacturing. September 1, 2016. ... FH) Christian Wolf, have for the first time ever applied the medical imaging technique of optical coherence tomography to ...
Axsun Technologies, A Wholly-Owned Subsidiary of Volcano Corporation, Announces Breakthrough Integrated Light Source...
... resolution Optical Coherence Tomography (OCT) and Forward-Looking IVUS systems and catheters. Currently, more than 4,700 ... Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging. 200kHz High ... MEMs-based optical and mechanical components, optical fiber design, manipulation and assembly, light sources used in optical ... This approach to optical engines builds on over 10 years of Axsuns core integrated light source technology and is protected by ...
Changes in viscoelastic properties of articular cartilage in early stage of osteoarthritis, as determined by optical coherence...
... stress relaxation optical coherence straingraphy (SR-OCSA). The purpose of this study was to establish an approach for ... We developed an optical coherence tomography-based strain rate tomography method: ... as determined by optical coherence tomography-based strain rate tomography ... Stress relaxation optical coherence straingraphy (SR-OCSA) system. a Illustration of the experimental apparatus. b Photograph ...
Optical coherence tomography angiography in diabetes and diabetic retinopathy | NTU Singapore
Optical coherence tomography angiography in diabetes and diabetic retinopathy. Authors: Chua, Jacqueline. Sim, Ralene. Tan, ... Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by ... Optical coherence tomography angiography in diabetes and diabetic retinopathy. Journal of Clinical Medicine, 9(6), 1723-. https ...
Domain optical coherenceAngiographyGlobal optical coherence tomograPolarization-sensitive optical coherenceAbstractSpectralMicroscopyRetinaOphthalmologyScansRetinal thickness measurementsThicknessMethodsSwept-sourceGlaucomaInterferometryDiabeticLasersNorth AmericaMeasurementsDiagnosisDiffuseEdmund OpticsSociety of AmericaFindingsNoninvasiveVivoImagingRoughnessICGA2017EvaluationMeasurementDermatologyDiagnosticUltrasoundOpticsPenetration depthApplicationsFibers2016LightSpatialClinicalScan
Domain optical coherence11
- In this work, a mid-infrared spectral-domain optical coherence tomography system operating at a central wavelength of 4 µm and an axial resolution of 8.6 µm is demonstrated. (nature.com)
- In this study, we propose a spectral-domain optical coherence tomography (OCT) method that employs pulse irradiation to capture an interferogram and continuous wavelet transform (CWT) for data analysis. (spie.org)
- Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography. (escholarship.org)
- The purpose was to create a three-dimensional (3-D) model of circumferential aqueous humor outflow (AHO) in a living human eye with an automated detection algorithm for Schlemm's canal (SC) and first-order collector channels (CC) applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired circumferentially around the limbus. (escholarship.org)
- Kanngießer, Jonas Peter: Wavefront shaping approaches for spectral domain optical coherence tomography. (uni-hannover.de)
- To compare the penetration of riboflavin using a microscope-integrated real time spectral domain optical coherence tomography (ZEISS OPMI LUMERA 700 and ZEISS RESCAN 700) in keratoconus patients undergoing accelerated collagen crosslinking (ACXL) between epithelium on (epi-on) and epithelium off (epi-off). (maastrichtuniversity.nl)
- B, Spectral-domain optical coherence tomography scan shows diffuse retinal thickening with cystic areas of low reflectivity predominantly in the inner nuclear and outer plexiform layers. (aao.org)
- Spectral-Domain Optical Coherence Tomography Findings as Prognostic Factors in Patients with Acute Central Serous Chorioretinopathy. (dergisi.org)
- Choroidal neovascularization subtype and activity were evaluated using spectral domain optical coherence tomography, infrared light, fundus autofluorescence, fluorescein angiography (FA), and indocyanine green angiography (ICGA). (unimi.it)
- RESULTS: The interobserver k regarding the types of CNV was 0.69 for multiimaging, 0.63 for spectral domain optical coherence tomography, 0.43 for FA, and 0.46 for ICGA. (unimi.it)
- The k values for interobserver for retreatment decision were 0.77 for multiimaging, 0.88 for spectral domain optical coherence tomography, 0.61 for infrared, 0.37 for fundus autofluorescence, 0.25 for FA, and 0.23 for ICGA. (unimi.it)
- This study instends to investigate the potential of Optical Coherence Tomography Angiography (OCTA) device to image and describe quantitatively the vascularization in eyes diagnosed with herpetic leucoma and to discuss and review the usefulness of this technique in this pathology. (researchsquare.com)
- All eyes underwent anterior segment Slit-Lamp photography (SLP), and Optical Coherence Tomography Angiography (OCT) with en-face, b-scans and c-scans imaging. (researchsquare.com)
- Purpose To describe en face swept-source optical coherence tomography (SS-OCT) findings in the retinal pigment epithelium (RPE) and choroid and to correlate them with fluorescein angiography (FA) and/or indocyanine green angiography (ICGA) in neovascular age-related macular degeneration (AMD). (bmj.com)
- Conclusions En face SS-OCT is a rapid, non-invasive, high-resolution, promising technology, which allows a complementary study to angiography of neovascular AMD. (bmj.com)
- There is a correlation between angiography and en face SS-OCT images in neovascular AMD. (bmj.com)
- Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood cells. (ntu.edu.sg)
- Methods: The "Eye Determinants of Cognition" (EyeDOC) study recruited a biracial, population-based sample of participants from two sites: Jackson, MS, and Washington Co, MD. Optical coherence tomographic angiography (OCTA) was used to capture vessel density (VD) from a 6 × 6 mm scan of the macula in several vascular layers from 2017 to 2019. (elsevier.com)
- Important aspects of workup regarding diabetic retinopathy include fasting glucose and hemoglobin A1c, fluorescein angiography, optical coherence tomography, and B-scan ultrasonography. (medscape.com)
- The investigations included complete slit lamp and fundoscopy examinations, automated visual field analysis, Amsler charting, fundus fluorescein angiography and optical coherence tomography. (who.int)
- Purpose: The aim of this study was to evaluate 1-year quantitative changes in specific inflammatory parameters on optical coherence tomography (OCT) / optical coherence tomography angiography (OCTA) in diabetic macular edema (DME) treated with subthreshold micropulse laser (SMPL). (elsevier.com)
- The optical coherence tomography and the optical coherence tomography-angiography en face (Figs. (canadianjournalofophthalmology.ca)
Global optical coherence tomogra5
- The global optical coherence tomography market is expected to grow at a CAGR of 10.9% over the forecast period i.e. 2017-2024. (researchnester.com)
- Moreover, the global optical coherence tomography market is projected to account for noteworthy sales of USD 1.8 Billion by 2024. (researchnester.com)
- The global optical coherence tomography market is segment into type, device type, application, technology, end user and region. (researchnester.com)
- The global Optical Coherence Tomography market research report offers extensive statistical analysis to impart a deeper understanding of the Optical Coherence Tomography industry and the changing dynamics of the business sphere. (sngine.com)
- The report on the global Optical Coherence Tomography market discusses in depth the current and emerging trends of the industry and discusses in detail the advancements in the technological and product sector. (sngine.com)
Polarization-sensitive optical coherence1
- The results of techniques like polarization-sensitive optical coherence tomography PS-OCT , scanning laser polarimetry, or polarization microscopy are contradictory. (unican.es)
- abstract = "In this work we investigate three techniques for estimation of the non-linear phase present due to defocus in opticalcoherence tomography, and apply them with the angular spectrum method. (dtu.dk)
- Nevertheless, the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical components in this spectral region, resulting in slow acquisition, low sensitivity, and poor axial resolution. (nature.com)
- We present an application of massively parallel processing of quantitative flow measurements data acquired using spectral optical coherence microscopy (SOCM). (mendeley.com)
- As SOCM constitutes the microscopy counterpart to spectral optical coherence tomography (SOCT), the developed processing procedure can be applied to both imaging modalities. (mendeley.com)
- Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography. (mendeley.com)
- Microscopy and coherence tomography systems, LIDAR and LADAR, fiber-optic sensors. (mit.edu)
- Since its first in vivo use for the retina, optical coherence tomography (OCT) imaging has revolutionized the ability to evaluate the eye and its structures with unprecedent resolution. (researchsquare.com)
- Purpose: To identify the pathologies of the vitreoretinal interface by Optical Coherence Tomography OCT of the retina in Lomé. (scirp.org)
- Cross-sectional tomographs of the retina profiling optical reflectivity in a thin, optical slice of tissue are obtained with a longitudinal resolution of 10 μm. (nyu.edu)
- Optical coherence tomography also was used to evaluate the vitreoretinal interface in patients' fellow eyes and was able to detect small separations of the posterior hyaloid from the retina. (nyu.edu)
- Optical coherence tomography (OCT) uses light to generate a cross-sectional image of the retina. (medscape.com)
- Optical coherence tomography (OCT) captures reflected light from retinal structures to create a cross-sectional image of the retina, like histologic sections as seen with a light microscope. (medscape.com)
- Optical coherence tomography (OCT) has been established as one of the most successful and significant optical techniques for biophotonics and clinical biomedical imaging, most notably within the field of ophthalmology. (nature.com)
- Originally developed for ophthalmology, Optical Coherence Tomography (OCT) now spreads over to a variety of applications. (toptica.com)
- Optical coherence tomography has emerging applications in ophthalmology, oncology, dermatology and others. (researchnester.com)
- First described in 1991, 1 optical coherence tomography (OCT) has improved ultrastructural imaging and diagnosis in ophthalmology and in multiple other fields, including cardiology, dermatology, gastroenterology, and urology. (arvojournals.org)
- Anterior chamber depth (ACD) change after pupillary dilation is correlated with lens vault (LV) and anterior chamber width (ACW), as observed by swept-source optical coherence tomography (SS-OCT) at both horizontal and vertical scans in patients with primary angle closure suspect and cataract. (lww.com)
- OCT scans of a tape roll acquired with electronically controlled optical sampling (ECOPS) (Courtesy of Stefan Kray). (toptica.com)
- Deep Learning Based Staging of Bone Lesions From Computed Tomography Scans. (cdc.gov)
Retinal thickness measurements3
- Objective: To determine the repeatability and reproducibility of retinal thickness measurements with the fast macular thickness mapping protocol of Stratus optical coherence tomography. (elsevier.com)
- Conclusion: With the fast macular thickness mapping protocol of Stratus ocular coherence tomography, our results indicate that retinal thickness measurements in dilated and undilated eyes of healthy subjects and diabetic patients with CSME are repeatable and reproducible. (elsevier.com)
- Evaluation of intraocular pressure, choroidal and retinal thickness measurements using optical coherence tomography in non - diabetic haemodialysis patients. (akiugydytojai.lt)
- In doing so, the first practical mid-infrared optical coherence tomography system is demonstrated, with immediate applications in real-time non-destructive testing for the inspection of defects and thickness measurements in samples that exhibit strong scattering at shorter wavelengths. (nature.com)
- Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical tablets and pellets directly. (lancs.ac.uk)
- Optical coherence tomography was used to examine 49 patients with the clinical diagnosis of idiopathic full-thickness macular hole, impending macular hole, epimacular membrane with macular pseudohole, or partial-thickness hole. (nyu.edu)
- Even with these limitations we conclude that the data presented in this study represent an important first step to develop a noninvasive optical tool that can reliably distinguish between superficial-partial and deep-partial thickness burn wounds. (careersfromscience.org)
- As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some pharmaceutical coatings may not be measurable altogether. (lancs.ac.uk)
- Methods: Optical coherence tomography is analogous to ultrasound except that optical rather than acoustic reflectivity is measured. (nyu.edu)
- Transmission Systems - Parallel-plate optical waveguide, modes (ray and wave-optics methods). (mit.edu)
- However, most of these methods require sophisticated modeling of optical and acoustic transportations, producing challenges for real-time imaging. (cdc.gov)
- Integration of LSI and other optical imaging methods such as Spatial Frequency Domain Imaging  is expected to yield a device that enables robust characterization of the severity of burn wounds. (careersfromscience.org)
- Axsun believes this proprietary optical engine design raises the bar on imaging speed and overcomes fundamental limitations of laser-based designs for swept source OCT light sources. (ptca.org)
- Here, we present a combined photoacoustic remote sensing (PARS) microscope and swept source optical coherence tomography (SS-OCT) system designed to circumvent these diagnostic limitations. (arxiv.org)
- Dubey D, Shanmugam M, Ramanjulu R, Mishra KC, Doshi B. Swept source optical coherence tomography in globe perforation. (who.int)
- Purpose: To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error. (elsevier.com)
- Advanced Imaging for Glaucoma Study Group 2016, ' Regression analysis of optical coherence tomography disc variables for glaucoma diagnosis ', Journal of Glaucoma , vol. 25, no. 8, pp. 634-642. (elsevier.com)
- Optical coherence tomography (OCT) is an efficient, non-invasive imaging modality that utilizes light interferometry to visualize and quantify neural tissue microstructure with high resolution, accuracy, and reproducibility. (medscape.com)
- OCT relies on low coherence interferometry utilizing spectrally broad light sources like superluminescent diodes or femtosecond lasers, since the resolution of OCT is determined by the inverse bandwidth of the light source. (toptica.com)
- Ballistic scanners utilizing ultrafast time entryways and optical intelligence tomography utilizing the interferometry guideline are only two of the wellknown imaging frameworks that depend on ballistic photon discovery to make diffraction-restricted pictures. (alliedacademies.org)
- Andrei V. Zvyagin, Elwyn D. J. Smith, and David D. Sampson, "Delay and dispersion characteristics of a frequency-domain optical delay line for scanning interferometry," J. Opt. (optica.org)
- The reflective frequency-domain optical delay line employing a diffraction grating, a lens, and a tiltable mirror has emerged as a device particularly suitable for interferometry and optical coherence tomography. (optica.org)
- Optical coherence tomography allows for various measurements of skin but the utility of the device in determining properties of normal and wounded skin in diabetic patients is unknown. (jfas.org)
- Optical Coherence Tomography with fs Fiber Lasers and ECOPS , Laser Magazin, 2009, 2-3, pp. 62-94. (toptica.com)
- Axsun is a leading developer and supplier of tunable lasers for OCT imaging, offering the highest speed integrated optical products on the market today," explained Dale Flanders, President of Axsun. (ptca.org)
- In terms of geography, North America is projected to lead the market of optical coherence tomography during the forecast period aided by U.S. In addition to this, the growth of North America optical coherence tomography market is attributed to various factors such as presence of major key vendors along with growing research and development activities related to imaging diagnostic products. (researchnester.com)
- Therefore, quantitative PAT, such as absolute oxygen saturation (sO 2 ) quantification, requires knowledge of the local optical fluence, which can be estimated only through invasive measurements or sophisticated modeling of light transportation. (cdc.gov)
- In line with these advances, a new imaging modality-optical coherence tomography (OCT)-has emerged as an essential adjunct for the diagnosis and monitoring of patients with AMD. (nih.gov)
- The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities that enable disease diagnosis from living patients without excising tissues from the body. (photonicsjobs.com)
- The procedure may likewise be alluded to as diffuse optical tomography close to infrared optical tomography or fluorescence diffuse optical tomography, contingent upon the utilization.In neuroscience, utilitarian estimations made utilizing NIR frequencies, DOI procedures may characterize as practical close to infrared spectroscopy. (alliedacademies.org)
- December 14, 2017, Barrington, N.J. - Edmund Optics® (EO), the premier provider of optical components, introduces a new Optical Coherence Tomography (OCT) Imaging System from Lumedica, the OQ LabScope. (labmanager.com)
- Becca Charboneau, Solutions Engineer for Edmund Optics, will be joined by Dr. Adam Wax, Founder of Lumedica, for our next webinar on Optical Coherence Tomography (OCT). Topics discussed will include: an overview of OCT, key applications, and how to select the proper optics for your OCT system. (edmundoptics.com)
- She joined Edmund Optics in 2021 and has been working closely with our life science customers to provide them with custom optical solutions based around their system needs. (edmundoptics.com)
Society of America1
- He is a fellow of the Optical Society of America, SPIE, and AIMBE and is inventor on 19 US patents. (edmundoptics.com)
- The findings were confirmed on anterior segment optical coherence tomography (ASOCT) [Figure 1] c. (ijoreports.in)
- Optical coherence tomography (OCT) is a depth-resolved, noninvasive, non-destructive imaging modality, the use of which has yet to be fully realized in developmental biology. (duke.edu)
- Conclusion: Optical coherence tomography appears potentially useful as a new, noninvasive, diagnostic technique for visualizing and quantitatively characterizing macular holes and assessing fellow eyes of patients with a macular hole. (nyu.edu)
- Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-resolution in vivo imaging of retinal tissue. (medscape.com)
- Full-Field Optical Coherence Tomography (FF-OCT or Full-Field OCT) is ideally suited for the in vitro examination of tissue samples as well as for the in vivo examination of patient tissue. (fraunhofer.de)
- High-resolution and rapid in-vitro and in-vivo tissue diagnostics for pre- and intraoperative use in ENT diseases for faster treatment and avoidance of tissue sampling through optical biopsies. (fraunhofer.de)
- The fellowship will focus on high resolution OCT imaging devices, including development of novel optical techniques, engineering of in vivo endoscopic probes, and translation to clinical use. (photonicsjobs.com)
- have recently published a paper investigating the elastic properties of human skin in vivo via the optical coherence tomography. (cdc.gov)
- In this regard, OCT stands out from other traditional NDT techniques, such as high-frequency laser ultrasonic (LUS) imaging, terahertz (THz) imaging, and micro X-ray computed tomography (μCT), each with its own advantages and disadvantages. (nature.com)
- Join us for a demonstration on selecting the proper optical components for your OCT system for non-invasive, high-resolution imaging. (edmundoptics.com)
- Publications: Nevet, A., Michaeli, T. & Orenstein, M. Second-order optical coherence tomography: deeper and turbulence-free imaging . (toptica.com)
- Clinical optical imaging is the utilization of light as an investigational imaging strategy for clinical applications. (alliedacademies.org)
- Optical imaging frameworks might be partitioned into diffusive and ballistic imaging frameworks. (alliedacademies.org)
- The longing for an indicative optical imaging methodology has spurred the advancement of picture remaking techniques including arrangement of the backwards issue. (alliedacademies.org)
- Optical coherence tomography is referred to a non-invasive imaging diagnostic test. (researchnester.com)
- PURPOSE: Enhanced depth imaging (EDI) optical coherence tomography (OCT) has emerged as a novel tool for qualitative and quantitative choroidal assessment in posterior uveitis. (ucl.ac.uk)
- Historically, common imaging modalities, such as magnetic resonance imaging (MRI) and computed tomography (CT), have used agents such as gadolinium or iodinated contrast to further improve diagnostic capabilities and visualization of pathology and tissue structure. (arvojournals.org)
- Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. (duke.edu)
- FH) Christian Wolf, have for the first time ever applied the medical imaging technique of optical coherence tomography to monitor the Additive Manufacturing process. (metal-am.com)
- We acquired Axsun for their significant expertise spanning a broad range of disciplines within optics and photonics - including the design and manufacture of MEMs-based optical and mechanical components, optical fiber design, manipulation and assembly, light sources used in optical imaging and spectroscopy, and sophisticated electronics and electro-mechanical systems needed to support complete solutions. (ptca.org)
- Optical coherence tomography imaging of normal, chronologically aged, photoaged and photodamaged skin: a systematic review. (jfas.org)
- Optical coherence tomography (OCT) enables sub-surface three dimensional imaging with micrometer resolution. (uni-hannover.de)
- First applications to optical coherence tomography were shown to extend the penetration depth as well as to improve the signal-to-noise ratio when imaging biological tissue. (uni-hannover.de)
- Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging? (elsevier.com)
- Dive into the research topics of 'Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging? (elsevier.com)
- Adaptive Optical Systems - Wavefront measurement systems, sharpness function, Unconventional AO, wavefront correctors, stellar imaging and star-wars applications. (mit.edu)
- Keyword pattern analysis showed that magnetic resonance imaging, optical coherence tomography, expanded disability status, demyelination, and epidemiology were the major themes of multiple sclerosis research in Arab countries. (who.int)
- Photoacoustic tomography (PAT) is a hybrid imaging technique that has broad preclinical and clinical applications. (cdc.gov)
- Association of cognitive impairment with optical coherence tomography and magnetic resonance imaging changes in multiple sclerosis", 31st CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MULTIPLESCLEROSIS, 7 - 10 October 2015, Barcelona, Spain. (akiugydytojai.lt)
- Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic, sensing, detection and imaging needs of our OEM and end-user customers. (photonics.com)
- We offer state of the art testing including but not limited to Optos imaging, Visual Fields, OCT (Optical coherence tomography) and MPOD (Macular pigment testing) and also the most fashionable and trendiest frames available. (opticalnearme.com)
- This study demonstrates the use of optical coherence tomography (OCT) to simultaneously characterize the roughness of the tablet core and coating of pharmaceutical tablets. (strath.ac.uk)
- Vertical B-scan, en-face and 3-D images were produced to calculate surface and dermal-epidermal junction roughness, the optical attenuation coefficient, a measure of light absorption and scattering, and blood flow metrics. (jfas.org)
- CONCLUSION: Optical coherence tomography and infrared evaluations of CNV activity were reproducible and strongly associated with multiimaging, whereas FA and ICGA evaluations showed poor reproducibility. (unimi.it)
- SPIE - International Society for Optical Engineering, 2017. (dtu.dk)
- Retinal pathology as a new biomarker in MS: evaluation by optical coherence tomograph. (akiugydytojai.lt)
- Measurement systems for optical coherence tomography (OCT) therefore offer great diagnostic added value due to their high resolution and measurement speed. (fraunhofer.de)
- Advances in optical coherence tomography in dermatology-a review. (jfas.org)
- Purpose: To assess the potential of a new diagnostic technique called optical coherence tomography (OCT) for diagnosing and monitoring macular holes. (nyu.edu)
- In PAT, tissue chromophores, such as oxygenated hemoglobin (HbO 2 ) and deoxygenated hemoglobin (Hb), absorb optical energy and emit acoustic waves that are detected by ultrasound transducers. (cdc.gov)
- Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography , Optics Express, 2010, 18(10), pp. 9976-9990. (toptica.com)
- The potential for improving the penetration depth of optical coherence tomography systems by using light sources with longer wavelengths has been known since the inception of the technique in the early 1990s. (nature.com)
- The images produced by the mid-infrared system are compared with those delivered by a state-of-the-art ultra-high-resolution near-infrared optical coherence tomography system operating at 1.3 μm, and the potential applications and samples suited for this technology are discussed. (nature.com)
- To identify and evaluate the use of contrast agents in optical coherence tomography (OCT) for ophthalmic applications. (arvojournals.org)
- Current state-of-the-art commercially available OCT systems for NDT operate in the 1.3-μm wavelength range, utilizing the low water absorption and the maturity of optical fibers and components developed for telecommunications in this region. (nature.com)
- Europe region captured the second largest market of optical coherence tomography in terms of revenue in 2016. (researchnester.com)
- This approach to optical engines builds on over 10 years of Axsun's core integrated light source technology and is protected by a number of issued patents. (ptca.org)
- Temporal and spatial coherence, two-beam and multiple-beam interference, interferometers. (mit.edu)
- Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss. (listlabs.com)
- Arrow indicates direction of the optical coherence tomography scan. (cdc.gov)
- With a compact design, intuitive touch-screen interface, and nine IOL formulas, this A-scan provides advanced capabilities for identifying optical pathologies. (emseye.com)