Tomography optical coherence. Medical search

An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Imaging methods that result in sharp images of objects located on a chosen plane and blurred images located above or below the plane.

An oval area in the retina, 3 to 5 mm in diameter, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototropic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)

Methods and procedures for the diagnosis of diseases of the eye or of vision disorders.

A view of the world and the individual's environment as comprehensible, manageable, and meaningful, claiming that the way people view their life has a positive influence on their health.

Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.

The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve.

Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.

Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.

Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)

Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.

The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.

Measurement of distances or movements by means of the phenomena caused by the interference of two rays of light (optical interferometry) or of sound (acoustic interferometry).

Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.

Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)

Examination of the interior of the eye with an ophthalmoscope.

LIGHT, it's processes and properties, and the characteristics of materials interacting with it.

An area approximately 1.5 millimeters in diameter within the macula lutea where the retina thins out greatly because of the oblique shifting of all layers except the pigment epithelium layer. It includes the sloping walls of the fovea (clivus) and contains a few rods in its periphery. In its center (foveola) are the cones most adapted to yield high visual acuity, each cone being connected to only one ganglion cell. (Cline et al., Dictionary of Visual Science, 4th ed)

The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

The front third of the eyeball that includes the structures between the front surface of the cornea and the front of the VITREOUS BODY.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed)

An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.

The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.

Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.

Method of measuring and mapping the scope of vision, from central to peripheral of each eye.

Examination of the angle of the anterior chamber of the eye with a specialized optical instrument (gonioscope) or a contact prism lens.

A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) retinal pigment epithelial cells. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the fovea centralis. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with retinal holes, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291)

Descriptive anatomy based on three-dimensional imaging (IMAGING, THREE-DIMENSIONAL) of the body, organs, and structures using a series of computer multiplane sections, displayed by transverse, coronal, and sagittal analyses. It is essential to accurate interpretation by the radiologist of such techniques as ultrasonic diagnosis, MAGNETIC RESONANCE IMAGING, and computed tomography (TOMOGRAPHY, X-RAY COMPUTED). (From Lane & Sharfaei, Modern Sectional Anatomy, 1992, Preface)

Methods of creating machines and devices.

The total area or space visible in a person's peripheral vision with the eye looking straightforward.

The light sensitive outer portion of a retinal rod or a cone photoreceptor cell. The outer segment contains a stack of disk membranes laden with photoreceptive pigments (RETINAL PIGMENTS). The outer segment is connected to the inner segment by a PHOTORECEPTOR CONNECTING CILIUM.

Measurement of the thickness of the CORNEA.

The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.

The inner portion of a retinal rod or a cone photoreceptor cell, situated between the PHOTORECEPTOR CONNECTING CILIUM and the synapse with the adjacent neurons (RETINAL BIPOLAR CELLS; RETINAL HORIZONTAL CELLS). The inner segment contains the cell body, the nucleus, the mitochondria, and apparatus for protein synthesis.

Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.

Projection of near-IR light (INFRARED RAYS), in the 700-1000 nm region, across an object in parallel beams to an array of sensitive photodetectors. This is repeated at various angles and a mathematical reconstruction provides three dimensional MEDICAL IMAGING of tissues. Based on the relative transparency of tissues to this spectra, it has been used to monitor local oxygenation, brain and joints.

The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.

A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.

Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.

Devices for examining the interior of the eye, permitting the clear visualization of the structures of the eye at any depth. (UMDNS, 1999)

Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of the uvea.

Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

The pressure of the fluids in the eye.

Detachment of the corpus vitreum (VITREOUS BODY) from its normal attachments, especially the retina, due to shrinkage from degenerative or inflammatory conditions, trauma, myopia, or senility.

Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.

A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.

The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.

Instruments for RETINOSCOPY that determines the refractive state of the EYE, such as the degree of NEARSIGHTEDNESS; FARSIGHTEDNESS; or ASTIGMATISM. In principle, a retinoscope provides a light source to illuminate the RETINA, and then locates the aerial image of the retina in space to obtain an index of the refractive quality of the patient's lens system.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

The distance between the anterior and posterior poles of the eye, measured either by ULTRASONOGRAPHY or by partial coherence interferometry.

Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).

An exudate between the RETINA and CHOROID from various sources including the vitreous cavity, SUBARACHNOID SPACE, or abnormal vessels.

Excessive axial myopia associated with complications (especially posterior staphyloma and CHOROIDAL NEOVASCULARIZATION) that can lead to BLINDNESS.

A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.

Measurement of the index of refraction (the ratio of the velocity of light or other radiation in the first of two media to its velocity in the second as it passes from one into the other).

Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

A vitreoretinal dystrophy characterized by splitting of the neuroretinal layers. It occurs in two forms: degenerative retinoschisis and X chromosome-linked juvenile retinoschisis.

Recording of electric potentials in the retina after stimulation by light.

Optic disk bodies composed primarily of acid mucopolysaccharides that may produce pseudopapilledema (elevation of the optic disk without associated INTRACRANIAL HYPERTENSION) and visual field deficits. Drusen may also occur in the retina (see RETINAL DRUSEN). (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p355)

Method of making images on a sensitized surface by exposure to light or other radiant energy.

The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)

The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)

Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

Colloid or hyaline bodies lying beneath the retinal pigment epithelium. They may occur either secondary to changes in the choroid that affect the pigment epithelium or as an autosomal dominant disorder of the retinal pigment epithelium.

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

A pathological process consisting of the formation of new blood vessels in the CHOROID.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.

Nerve cells of the RETINA in the pathway of transmitting light signals to the CENTRAL NERVOUS SYSTEM. They include the outer layer of PHOTORECEPTOR CELLS, the intermediate layer of RETINAL BIPOLAR CELLS and AMACRINE CELLS, and the internal layer of RETINAL GANGLION CELLS.

Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.

Specialized PHOTOTRANSDUCTION neurons in the vertebrates, such as the RETINAL ROD CELLS and the RETINAL CONE CELLS. Non-visual photoreceptor neurons have been reported in the deep brain, the PINEAL GLAND and organs of the circadian system.

The administration of substances into the VITREOUS BODY of the eye with a hypodermic syringe.

Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.

General disorders of the sclera or white of the eye. They may include anatomic, embryologic, degenerative, or pigmentation defects.

Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.

The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.

A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.

A form of glaucoma in which the intraocular pressure increases because the angle of the anterior chamber is blocked and the aqueous humor cannot drain from the anterior chamber.

Pieces of glass or other transparent materials used for magnification or increased visual acuity.

A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.

Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from EYE DISEASES; OPTIC NERVE DISEASES; VISUAL PATHWAY diseases; OCCIPITAL LOBE diseases; OCULAR MOTILITY DISORDERS; and other conditions (From Newell, Ophthalmology: Principles and Concepts, 7th ed, p132).

An objective determination of the refractive state of the eye (NEARSIGHTEDNESS; FARSIGHTEDNESS; ASTIGMATISM). By using a RETINOSCOPE, the amount of correction and the power of lens needed can be determined.

Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.

A tomographic technique for obtaining 3-dimensional images with transmission electron microscopy.

An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.

Changes in the observed frequency of waves (as sound, light, or radio waves) due to the relative motion of source and observer. The effect was named for the 19th century Austrian physicist Johann Christian Doppler.

Measurements of the height, weight, length, area, etc., of the human and animal body or its parts.

The veins and arteries of the HEART.

Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)

The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).

The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.

The use of green light-producing LASERS to stop bleeding. The green light is selectively absorbed by HEMOGLOBIN, thus triggering BLOOD COAGULATION.

A visual impairment characterized by the accumulation of fluid under the retina through a defect in the retinal pigment epithelium.

A technique of diagnostic imaging of RETINA or CORNEA of the human eye involving the measurement and interpretation of polarizing ELECTROMAGNETIC WAVES such as radio or light waves. It is helpful in the diagnosis of GLAUCOMA; MACULAR DEGENERATION; and other retinal disorders.

Measurement of ocular tension (INTRAOCULAR PRESSURE) with a tonometer. (Cline, et al., Dictionary of Visual Science, 4th ed)

The use of statistical and mathematical methods to analyze biological observations and phenomena.

A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.

Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.

The property of nonisotropic media, such as crystals, whereby a single incident beam of light traverses the medium as two beams, each plane-polarized, the planes being at right angles to each other. (Cline et al., Dictionary of Visual Science, 4th ed)

Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.

The administration of substances into the eye with a hypodermic syringe.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.

The measurement of curvature and shape of the anterior surface of the cornea using techniques such as keratometry, keratoscopy, photokeratoscopy, profile photography, computer-assisted image processing and videokeratography. This measurement is often applied in the fitting of contact lenses and in diagnosing corneal diseases or corneal changes including keratoconus, which occur after keratotomy and keratoplasty.

A tricarbocyanine dye that is used diagnostically in liver function tests and to determine blood volume and cardiac output.

A form of RETINAL DEGENERATION in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision.

Tomography using x-ray transmission.

Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

The blood vessels which supply and drain the RETINA.

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.

A group of disorders involving predominantly the posterior portion of the ocular fundus, due to degeneration in the sensory layer of the RETINA; RETINAL PIGMENT EPITHELIUM; BRUCH MEMBRANE; CHOROID; or a combination of these tissues.

The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.

Hereditary, progressive degeneration of the neuroepithelium of the retina characterized by night blindness and progressive contraction of the visual field.

The technology of transmitting light over long distances through strands of glass or other transparent material.

Lesions formed within the walls of ARTERIES.

An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.

Surgical removal of a section of the iris.

A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.

Radiography of the vascular system of the heart muscle after injection of a contrast medium.

Refraction of LIGHT effected by the media of the EYE.

A surgical procedure or KERATOPLASTY involving selective stripping and replacement of diseased host DESCEMET MEMBRANE and CORNEAL ENDOTHELIUM with a suitable and healthy donor posterior lamella. The advantage to this procedure is that the normal corneal surface of the recipient is retained, thereby avoiding corneal surface incisions and sutures.

Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.

The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)

Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.

Elements of limited time intervals, contributing to particular results or situations.

An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.

Microscopy using polarized light in which phenomena due to the preferential orientation of optical properties with respect to the vibration plane of the polarized light are made visible and correlated parameters are made measurable.

Behavior of LIGHT and its interactions with itself and materials.

Specialized ophthalmic technique used in the surgical repair and or treatment of disorders that include retinal tears or detachment; MACULAR HOLES; hereditary retinal disease; AIDS-related retinal infections; ocular tumors; MACULAR DEGENERATION; DIABETIC RETINOPATHY; and UVEITIS.

A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.

The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)

Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics.

Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)

A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)

A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.

X-ray image-detecting devices that make a focused image of body structures lying in a predetermined plane from which more complex images are computed.

Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.

Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.

Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.

The inner layer of CHOROID, also called the lamina basalis choroideae, located adjacent to the RETINAL PIGMENT EPITHELIUM; (RPE) of the EYE. It is a membrane composed of the basement membranes of the choriocapillaris ENDOTHELIUM and that of the RPE. The membrane stops at the OPTIC NERVE, as does the RPE.

Investigative and diagnostic methods and procedures based on the photoacoustic effect, which is the generation of SOUND WAVES from the absorption of ELECTROMAGNETIC RADIATION.

A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)

The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Autosomal dominant hereditary maculopathy with childhood-onset accumulation of LIPOFUSION in RETINAL PIGMENT EPITHELIUM. Affected individuals develop progressive central acuity loss, and distorted vision (METAMORPHOPSIA). It is associated with mutations in bestrophin, a chloride channel.

Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.

A layer of acellular matrix that lies beneath the CORNEAL EPITHELIUM and above the CORNEAL STROMA. It consists of randomly arranged COLLAGEN fibers in a condensed bed of intercellular substance. It provides stability and strength to the cornea.

Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.

Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.

The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.

A localized defect in the visual field bordered by an area of normal vision. This occurs with a variety of EYE DISEASES (e.g., RETINAL DISEASES and GLAUCOMA); OPTIC NERVE DISEASES, and other conditions.

Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.

Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).

A tooth's loss of minerals, such as calcium in hydroxyapatite from the tooth matrix, caused by acidic exposure. An example of the occurrence of demineralization is in the formation of dental caries.

Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.

Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Surgery performed on the eye or any of its parts.

Endoscopes for examining the interior of the esophagus.

Diagnostic tests conducted in order to measure the increment of active DENTAL CARIES over a period of time.

Narrowing or constriction of a coronary artery.

Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.

A layer of the cornea. It is the basal lamina of the CORNEAL ENDOTHELIUM (from which it is secreted) separating it from the CORNEAL STROMA. It is a homogeneous structure composed of fine collagenous filaments, and slowly increases in thickness with age.

Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

A form of GLAUCOMA in which chronic optic nerve damage and loss of vision normally attributable to buildup of intraocular pressure occurs despite prevailing conditions of normal intraocular pressure.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

The plan and delineation of prostheses in general or a specific prosthesis.

A group of rare, idiopathic, congenital retinal vascular anomalies affecting the retinal capillaries. It is characterized by dilation and tortuosity of retinal vessels and formation of multiple aneurysms, with different degrees of leakage and exudates emanating from the blood vessels.

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)

Endoscopic examination, therapy or surgery performed on the interior of blood vessels.

Introduction of substances into the body using a needle and syringe.

That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the microwave frequencies. They are used therapeutically as heat, and also to warm food in restaurants.

Substances used to allow enhanced visualization of tissues.

Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.

Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.

The comparison of the quantity of meaningful data to the irrelevant or incorrect data.

Photosensitive afferent neurons located primarily within the FOVEA CENTRALIS of the MACULA LUTEA. There are three major types of cone cells (red, blue, and green) whose photopigments have different spectral sensitivity curves. Retinal cone cells operate in daylight vision (at photopic intensities) providing color recognition and central visual acuity.

The X-shaped structure formed by the meeting of the two optic nerves. At the optic chiasm the fibers from the medial part of each retina cross to project to the other side of the brain while the lateral retinal fibers continue on the same side. As a result each half of the brain receives information about the contralateral visual field from both eyes.

The aperture in the iris through which light passes.

The protrusion of an organ or part of an organ into a natural or artificial orifice.

That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.

Permanent dilation of preexisting blood vessels (CAPILLARIES; ARTERIOLES; VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. It is characterized by the prominence of skin blood vessels, such as vascular spiders.

A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.

Chemical substances that are destructive to spermatozoa used as topically administered vaginal contraceptives.

Transmission of gene defects or chromosomal aberrations/abnormalities which are expressed in extreme variation in the structure or function of the eye. These may be evident at birth, but may be manifested later with progression of the disorder.

An X chromosome-linked abnormality characterized by atrophy of the choroid and degeneration of the retinal pigment epithelium causing night blindness.

Intravascular modalities for detection of vulnerable plaque: current status. (1/2999)

Progress in the diagnosis, treatment, and prevention of atherosclerotic coronary artery disease is dependent on a greater understanding of the mechanisms of coronary plaque progression. Autopsy studies have characterized a subgroup of high-risk, or vulnerable, plaques that result in acute coronary syndromes or sudden cardiac death. These angiographically modest plaques share certain pathologic characteristics: a thin, fibrous cap, lipid-rich core, and macrophage activity. Diagnostic techniques for vulnerable-plaque detection, including serologic markers and noninvasive and invasive techniques, are needed. Recent advances in intravascular imaging have significantly improved the ability to detect high-risk, or vulnerable, plaque in vivo by using various features of plaque vulnerability as methods of identification. The characteristic anatomy of a thin, fibrous cap overlying a lipid pool has promoted high-resolution imaging, such as intravascular ultrasound, optical coherence tomography, and intracoronary magnetic resonance. The lipid-rich core is identifiable by angioscopically detected color changes on the plaque surface or by its unique absorption of energy, or "Raman shift," of its cholesterol core, driving coronary spectroscopy. Finally, temperature heterogeneity arising at foci of plaque inflammation has prompted the development of intracoronary thermography. In this review, we will discuss these techniques, their relative advantages and limitations, and their potential clinical application. (+info)

Choroidal neovascularization characteristics and its size in optical coherence tomography. (2/2999)

The classification, size and activity of choroidal neovascularization (CNV) by optical coherence tomography (OCT) were compared with those obtained by fluorescein angiography (FA) and Indocyanine green angiography (ICG). This study included 32 patients (32 eyes) diagnosed as having CNV. The etiology of CNV was found to be age-related macular degeneration (AMD) or non-AMD. Patients were studied retrospectively by FA, ICG, and OCT. Of the 13 eyes with AMD, the boundary of the lesion could not be defined using FA in 7 patients. Among the 7 poorly defined CNV cases by FA, the identification of the boundary was possible in one case by OCT. The mean diameter of the classic well-defined lesions was 3500 +/- 421 microm by FA, 2624 +/- 1044 microm by ICG, and 1927 +/- 1272 microm by OCT. The size of the CNV by OCT was always smaller than by FA or ICG. Of the 19 eyes with Non-AMD, the boundary of the lesion could not be defined by FA in 5 patients. Among the 5 poorly defined cases by FA, the identification of the boundary was possible in 3 cases by OCT. The mean diameter of the well-defined CNV lesions was 2153 +/- 759 microm by FA, 1929 +/- 673 microm by ICG, and 1322 +/- 566 microm by OCT. Retinal thickness, which represents retinal edema, was found to be proportional to lesion size, although the relationship was not statistically significant. Regardless of CNV type, FA, ICG and OCT used in combination increase the specificity of diagnosis if their findings are compared. (+info)

Optical imaging of the cervix. (3/2999)

Recent advances in fiber optics, sources and detectors, imaging, and computer-controlled instrumentation have stimulated a period of unprecedented growth in the development of photonics technologies for a wide variety of diagnostic and therapeutic clinical applications. These include the application of quantitative optical spectroscopy and imaging for the detection of precancerous lesions in the uterine cervix, a topic of interest at the Second International Conference on Cervical Cancer, which was held April 11-14, 2002. Investigators have applied the Littenberg method of emerging technology assessment to new optical methods used to detect cervical neoplasia. Currently, such technologies as fluorescence spectroscopy (the combination of fluorescence and diffuse reflectance spectroscopy), tri-modal spectroscopy, and light-scattering spectroscopy that probe the spectral characteristics of tissue are being investigated. Optical technologies that create images of subcellular structure without biopsy subsequent to pathology that currently are under investigation include in vivo confocal imaging and optical coherence tomography. Numerous small studies have demonstrated the potential of these optical technologies. What remains to be elucidated are the fundamental biophysical origins of variations in remitted optical signals between normal and dysplastic tissue. Large multicenter randomized controlled trials are needed to confirm the detection and imaging capabilities of optical technology. Furthermore, the development of contrast agents that could boost detection with these technologies is needed, and basic biologic characterization of signals should be pursued. Applying the Littenberg assessment will help ensure that superior, not simply alternative, technologies are implemented. (+info)

Optical coherence tomography disc assessment in optic nerves with peripapillary atrophy. (4/2999)

BACKGROUND AND OBJECTIVE: Optical coherence tomography (OCT) is able to determine the optic disc margin automatically. The aim of this study was to investigate the accuracy of the automatic OCT optic nerve head measurements in the presence of peripapillary atrophy. PATIENTS AND METHODS: This was a cross-sectional, retrospective study. Thirty-one subjects with peripapillary atrophy underwent optic nerve head scanning with OCT version 3. Nineteen of the eyes were classified clinically as having glaucoma, nine had suspected glaucoma, and three were normal. Automatic OCT results were compared with manual tracing results. RESULTS: Significant differences were found between most OCT optic nerve head automated and manual disc assessment parameters; however, good agreement was found between the two methods for all parameters (intraclass correlation, 0.71 to 0.94). Areas under receiver operator characteristics curves for clinical status were similar for all parameters with both methods. CONCLUSION: Automated OCT optic nerve head analysis may be used in the clinical setting in the presence of peripapillary atrophy; however, caution should be used when comparing individual results with population-derived optic nerve head results. (+info)

Delayed regeneration of foveal cone photopigments in Vogt-Koyanagi-Harada disease at the convalescent stage. (5/2999)

PURPOSE: To evaluate the physiological characteristics of the macula in patients with Vogt-Koyanagi-Harada disease during the convalescent stage with specific reference to the kinetics of foveal cone photopigment regeneration. METHODS: Six eyes of three patients at the convalescent stage of Vogt-Koyanagi-Harada disease were studied. All the eyes had best corrected visual acuity of 1.0 or better and had had no recurrence of inflammation for at least 12 months after the last episode. Foveal cone densitometry (FCD), focal macular electroretinograms, color vision tests, two-color perimetry, and optical coherence tomography (OCT) were performed. RESULTS: No regeneration of cone photopigments was detected within the 7-minute testing time by FCD in all eyes at the first examination after the last episode. However, the other functional tests were normal, and the OCT-determined macular morphology was also normal. The regeneration kinetics of the foveal cone photopigment improved in three of six eyes at 36, 37, and 19 months after the last episode, whereas the other three remained delayed at 18, 18, and 49 months. CONCLUSIONS: These findings suggest that a disorder of the foveal cone photopigment regeneration, and its recovery, requires a significantly longer time than that of other macular functions in some patients with Vogt-Koyanagi-Harada disease. (+info)

Secondary retinal changes associated with choroidal naevi and melanomas documented by optical coherence tomography. (6/2999)

AIMS: To establish the characteristics of secondary retinal changes associated with the presence of choroidal melanomas and choroidal naevi as documented by optical coherence tomography (OCT). METHODS: Twenty patients with untreated choroidal melanoma and 40 patients with presumed choroidal naevi managed by regular observation were included in the study. OCT scans across the surface of the tumour and surrounding tissue were acquired for all participants. The appearance of retinal tissue on the OCT scans was considered to be abnormal if it did not display the well defined band structure characteristic of normal tissue on OCT scans. RESULTS: Serous retinal detachments were observed in all patients with choroidal melanoma and 18 out of 20 also had abnormal retinal structure or intra-retinal splitting in the tissue overlying the tumour. Out of the 40 patients with presumed choroidal naevi, 12 had serous detachments and three had either abnormal retinal structure or intra-retinal splitting overlying the lesion. CONCLUSIONS: Secondary retinal changes associated with choroidal lesions can be documented by OCT. These changes were observed in most patients with choroidal melanoma included in the study group but were far less prevalent in the patients with presumed choroidal naevi. OCT is also able to identify the presence of small serous detachments before they become clinically visible. Follow up of these patients is required to determine whether the OCT results may be of use in the differential diagnosis of small choroidal lesions. (+info)

Onset of pulsatile pressure causes transiently increased filtration through artery wall. (7/2999)

Convective fluid motion through artery walls aids in the transvascular transport of macromolecules. Although many measurements of convective filtration have been reported, they were all obtained under constant transmural pressure. However, arterial pressure in vivo is pulsatile. Therefore, experiments were designed to compare filtration under steady and pulsatile pressure conditions. Rabbit carotid arteries were cannulated and excised from male New Zealand White rabbits anesthetized with pentobarbitol sodium (30 mg/kg i.v. administered). Hydraulic conductance was measured in cannulated excised rabbit carotid arteries at steady pressure. Next, pulsatile pressure trains were applied within the same vessels, and, simultaneously, arterial distension was monitored using Optical coherence tomography (OCT). For each pulse train, the volume of fluid lost through filtration was measured (subtracting volume change due to residual distension) and compared with that predicted from steady pressure measurements. At 60- and 80-mmHg baseline pressures, the experimental filtration volumes were significantly increased compared with those predicted for steady pressure (P < 0.05). OCT demonstrated that the excess fluid volume loss was significantly greater than the volume that would be lost through residual distension (P < 0.05). After 30 s, the magnitude of the excess of fluid loss was reduced. These results suggest that sudden onset of pulsatile pressure may cause changes in arterial interstitial hydration. (+info)

Supplemental oxygen improves diabetic macular edema: a pilot study. (8/2999)

PURPOSE: Diabetic macular edema (DME) is the most common cause of moderate visual disability in persons of working age in the United States. The pathogenesis of DME is poorly understood. In this study, the effect of retinal hypoxia in the development and maintenance of DME was investigated. METHODS: Five patients with chronic DME despite at least one focal laser photocoagulation treatment (nine eyes) received 4 L/min of inspired oxygen by nasal cannula for 3 months. Best corrected visual acuity (VA) and retinal thickness, assessed by optical coherence tomography (OCT), were measured at baseline, during 3 months of oxygen treatment, and for 3 months after stopping oxygen. RESULTS: After 3 months of oxygen therapy, nine of nine eyes with DME at baseline showed a reduction in thickness of the center of the macula. Foveal thickness (FTH) above the normal range was reduced by an average of 43.5% (range, 14%-100%), excess foveolar thickness (CEN) was reduced by an average of 42.1% (range, 13%-100%), and excess macular volume was reduced by an average of 54% (range, 35%-100%). Statistical analyses suggested that these changes were unlikely to be due to chance (P = 0.0077 by Wilcoxon signed-rank test). Three eyes showed improvement in VA by at least 2 lines, one by slightly less than 2 lines, and five eyes showed no change. Three months after discontinuation of oxygen, five of the nine eyes showed increased thickening of the macula compared with when oxygen was discontinued. CONCLUSIONS: Supplemental inspired oxygen may decrease macular thickness due to DME, suggesting that retinal hypoxia is involved in the development and maintenance of DME. (+info)

Optical coherence tomography. Spie Milestone Series MS. 1998;147:324-7. Romero-Borja F, Venkateswaran K, Roorda A, Hebert T. " ... Optical coherence tomography (OCT) represents a powerful clinical tool for monitoring retinal physiology in patients. OCT uses ... "Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema ... with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography". ...

https://en.wikipedia.org/wiki/Scanning_laser_ophthalmoscopy

He is known for his leading role in the invention of a novel medical imaging modality named optical coherence tomography that ... Boyd, Kierstan (14 October 2015). "What Is Optical Coherence Tomography?". American Academy of Ophthalmology. Retrieved 8 ... Optical coherence tomography, Fellows of the American Physical Society, Fellows of the American Association for the Advancement ... "Optical Coherence Tomography". Science. 254 (5035): 1178-1181. doi:10.1126/science.1957169. PMC 4638169. PMID 1957169. ...

https://en.wikipedia.org/wiki/James_Fujimoto

"Articles that mention Joel S. Schuman". Optical Coherence Tomography News. Retrieved 2015-08-29. "Sight + Sound" (PDF). ... invented the optical coherence tomography (OCT) technology. This technology, allows a quick and noninvasive 3D map of the eye, ...

https://en.wikipedia.org/wiki/Joel_S._Schuman

1991). "Optical Coherence Tomography" (PDF). Science. 254 (5035): 1178-81. Bibcode:1991Sci...254.1178H. doi:10.1126/science. ... Another application of the Michelson interferometer is in optical coherence tomography (OCT), a medical imaging technique using ... Fercher, A.F. (1996). "Optical Coherence Tomography" (PDF). Journal of Biomedical Optics. 1 (2): 157-173. Bibcode:1996JBO.....1 ... exceeds coherence length of light beams. The nontrivial features of phase fluctuations in optical phase-conjugating mirror had ...

https://en.wikipedia.org/wiki/Michelson_interferometer

Quantum optical coherence tomography (QOCT). Entangled-photon ellipsometry. Entangled-photon cryptography. Entangled-photon ... "Variations on the Theme of Quantum Optical Coherence Tomography: A Review" (PDF). Quantum Information Processing. 11 (4): 903- ... Quantum Photonics: Optical heterodyne detection. Photon statistics and point processes. Single-photon detection at the retinal ... 19, Optical and Infrared Detectors (Second ed.). Berlin: Springer. pp. 229-300. ISBN 9783540707547. Retrieved 10 October 2021. ...

https://en.wikipedia.org/wiki/Malvin_Carl_Teich

In 2010 the company also acquired LightLab Imaging, a company that developed optical coherence tomography technology that helps ... The device uses fractional flow reserve for measuring intra-arterial pressure and optical coherence tomography technology, ... optical coherence tomography (OCT) imaging systems; structural heart repair products; and neurostimulation devices. The ...

https://en.wikipedia.org/wiki/St._Jude_Medical

"winner of Optical Coherence Tomography Award". 9 January 2011. Retrieved 11 September 2016. "Giovanni J. Ughi, PhD". Google ... is one of the inventors of multimodality Optical Coherence Tomography (OCT) and Laser-induced fluorescence molecular imaging, ... "Automatic segmentation of in-vivo intra-coronary optical coherence tomography images to assess stent strut apposition and ... "Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in ...

https://en.wikipedia.org/wiki/Giovanni_J._Ughi

"NASA - Optical Coherence Tomography Technology Demonstration". www.nasa.gov. Retrieved 2018-10-13. "What's Next for Twins Study ... She has since been studying Spaceflight-Associated Neuro-Ocular Syndrome, and sent an optical coherence tomography scanner up ...

https://en.wikipedia.org/wiki/Shannan_Moynihan

She completed her Ph.D. in biomedical engineering at Duke University in 2007, specialising in optical coherence tomography. Her ... Her research group develops new imaging devices and techniques based on optical coherence tomography, and developing point-of- ... Ellerbee, Audrey K. (2014-10-01). "Optical coherence tomography: Technology and applications". 2014 IEEE Photonics Conference: ... Her research in biomedical optics focuses on developing new imaging techniques and devices for optical coherence tomography and ...

https://en.wikipedia.org/wiki/Audrey_Ellerbee_Bowden

MS patients show axonal loss in the retina and optic nerve, which can be measured by Optical coherence tomography or by ... 2007). "Optical coherence tomography and disease subtype in multiple sclerosis". Neurology. 69 (22): 2085-2092. doi:10.1093/ ... March 2009). "Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis". Neurology. 72 (12 ... Evangelou, Nikos; Alrawashdeh, Omar S. M (2016). "Anatomy of the Retina and the Optic Nerve". Optical Coherence Tomography in ...

https://en.wikipedia.org/wiki/Pathology_of_multiple_sclerosis

"Ultrahigh-resolution full-field optical coherence tomography". Applied Optics. 43 (14): 2874-2883. Bibcode:2004ApOpt..43.2874D ... The advantage of this design its ability to compensate for chromatic dispersion and other optical aberrations. In the image of ...

https://en.wikipedia.org/wiki/Linnik_interferometer

Abazari, Azin; Allam, Souha S.; Adamus, Grazyna; Ghazi, Nicola G. (2016-11-21). "Optical Coherence Tomography Findings in ...

https://en.wikipedia.org/wiki/Autoimmune_retinopathy

Fractional flow reserve Intracoronary Optical Coherence Tomography Hector M. Garcia-Garcia, Bill D. Gogas, Patrick W. Serruys ... "Intracoronary Optical Coherence Tomography: A Comprehensive Review". JACC: Cardiovascular Interventions. 2 (11): 1035-1046. doi ...

https://en.wikipedia.org/wiki/Intravascular_ultrasound

Findings from optical coherence tomography were normal. Amsler grid test results were highly variable, and the locations of ...

https://en.wikipedia.org/wiki/Strait_of_Juan_de_Fuca_laser_incident

The optical contrast of gas vesicles also enables them to serve as contrast agents in optical coherence tomography, with ... "Biomolecular Contrast Agents for Optical Coherence Tomography" (PDF). bioRxiv. doi:10.1101/595157. S2CID 133072739. Shapiro MG ...

https://en.wikipedia.org/wiki/Gas_vesicle

... where he has pioneered new optical imaging technologies in the fields of optical coherence tomography, multi-photon microscopy ... "CAREER: Functional Optical Coherence Tomography for Neural Imaging". www.nsf.gov. Retrieved 2017-12-12. "Hans Sigrist Prize ... 2011). "Handheld Optical Coherence Tomography Scanner for Primary Care Diagnostics". IEEE Trans. Biomed. Eng. 58 (3): 741-744. ... While at MIT, he was involved in the invention and early development of optical coherence tomography (OCT). Boppart started the ...

https://en.wikipedia.org/wiki/Stephen_A._Boppart

Using optical coherence tomography (OCT), 18 layers can be identified in the retina. The layers and anatomical correlation are ... A relatively new technology, now becoming widely available, is optical coherence tomography (OCT). This non-invasive technique ... Meyer, Carsten H.; Saxena, Sandeep; Sadda, Srinivas R. (2017). Spectral domain optical coherence tomography in macular diseases ... "Past and Present Terminology for the Retinal and Choroidal Structures in Optical Coherence Tomography". European Ophthalmic ...

https://en.wikipedia.org/wiki/Retina

... optical coherence tomography can offer unique benefits. Optical coherence tomography angiography can help the physician see if ... Fundus autofluorescence and optical coherence tomography angiography are imaging modalities that can be used in the diagnosis. ... "Optical Coherence Tomography in Age-related Macular Degeneration". AMD book. Retrieved 8 December 2019. Malciolu Radu Alexandru ... These more subtle changes can be quantified by volumetric analyses of optical coherence tomography data. There are currently no ...

https://en.wikipedia.org/wiki/Geographic_atrophy

"Occult Hypotony Maculopathy Diagnosed With Optical Coherence Tomography". Archives of Ophthalmology. 123 (1): 113-114. doi: ...

https://en.wikipedia.org/wiki/Hypotony_maculopathy

Chen JC, Lee LR (2004). "Solar retinopathy and associated optical coherence tomography findings". Clin Exp Optom. 87 (6): 390- ... Prolonged optical exposure to sunlight, especially intense ultraviolet light, may be linked to cortical cataracts, and high ...

https://en.wikipedia.org/wiki/Health_effects_of_sunlight_exposure

High-speed optical coherence tomography of corneal opacities. Ophthalmology. 2007 Jul;114(7):1278-85. Plesea et al. Direct ... OCT Biomicroscopy is the use of optical coherence tomography (OCT) in place of slit lamp biomicroscopy to examine the ... Keratoconus diagnosis with optical coherence tomography pachymetry mapping. Ophthalmology 2008 Dec;115(12):2159-66. Eye ... Detailed visualization of the anterior segment using fourier-domain optical coherence tomography. Arch Ophthalmol 2008 June;126 ...

https://en.wikipedia.org/wiki/OCT_Biomicroscopy

"Solar retinopathy and associated optical coherence tomography findings." Archived 2006-09-27 at the Wayback Machine Clin Exp ...

https://en.wikipedia.org/wiki/Photic_retinopathy

Optical Coherence Tomography: A Novel Imaging Method for Post-lumpectomy Breast Margin Assessment-A Multi-reader Study. Acad ... 2007). Ultrahigh-resolution optical coherence tomography at 1.15 μm using photonic crystal fiber with no zero-dispersion ... An automated 3D registration method for optical coherence tomography volumes. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3873‐ ... Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector. Biomed Opt Express ...

https://en.wikipedia.org/wiki/Christine_P._Hendon

There is insufficient evidence that optical coherence tomography (OCT) is useful in diagnosing melanoma or squamous cell ... Cochrane Skin Group) (December 2018). "Optical coherence tomography for diagnosing skin cancer in adults". The Cochrane ... optical coherence tomography, the multispectral imaging technique, thermography, electrical bio-impedance, tape stripping and ...

https://en.wikipedia.org/wiki/Skin_cancer

"Optical Coherence Tomography: What It Is & How It's Used". Cleveland Clinic. Retrieved 2022-07-25. "Foveal Hypoplasia 2 , ... Today, a newer technology, optical coherence tomography (OCT) is used to detect foveal hypoplasia and does not require a dye. ... Recchia, Franco M.; Carvalho-Recchia, Cynthia A.; Trese, Michael T. (2002-11-01). "Optical Coherence Tomography in the ...

https://en.wikipedia.org/wiki/Macular_hypoplasia

Chen JC, Lee LR (November 2004). "Solar retinopathy and associated optical coherence tomography findings" (PDF). Clin Exp Optom ...

https://en.wikipedia.org/wiki/Sungazing

Some of these locations use a fundus camera, others use both fundus and optical coherence tomography (OCT) imaging devices, and ... "Teleophthalmology with optical coherence tomography imaging in the community". Clinical Ophthalmology. 5: 1673-1678. 2011. ... Recently, emerging retinal imaging modalities such as optical coherence tomography are capable of producing digital images of ... Kelly, SP; I Wallwork; D Haider; K Qureshi (2011). "Teleophthalmology with optical coherence tomography imaging in community ...

https://en.wikipedia.org/wiki/Teleophthalmology

Ah-kee, Elliott; Oladiwura, Dilys; Lim, Lik Thai; Scott, Angus (2014-05-19). "Macular optical coherence tomography findings ...

https://en.wikipedia.org/wiki/Berlin's_edema

Optical coherence tomography is frequently used to assess macular edema. Fluorescein angiography is used by retina specialists ... Optical coherence tomography (OCT) is used to determine the severity of edema and treatment response. Because fundoscopic ...

https://en.wikipedia.org/wiki/Diabetic_retinopathy

... s have proven useful in a wide variety of applications including optical coherence tomography, ... "Common-path interferometer for frequency-domain optical coherence tomography" (PDF). Applied Optics. 42 (34): 6953-6957. ... both of which interfere with the optical measurements. Precision measurements of an optical surface are also extremely ... It usually consists of a beam splitter, an optical flat, a biconvex diverger of short focal length and a light source such as a ...

https://en.wikipedia.org/wiki/Common-path_interferometer

Optical coherence tomography. *നേത്ര സംരക്ഷണ വിദഗ്ദ്ധർ. *നേത്ര രോഗങ്ങൾ. *അപവർത്തന ദോഷം. *അക്കൊമഡേഷൻ ...

https://ml.wikipedia.org/wiki/അസ്റ്റിഗ്മാറ്റിസം

Optical coherence tomography (OCT) is a medical technological platform used to assess ocular structures. The information is ... The origins of optical science (optics, as taught in a basic physics class) date back a few thousand years as evidence of the ... "Free NHS eye tests and optical vouchers". NHS. 14 August 2018.. *^ Agarwal, R. (2008), Integrating theory with practice, ... They provide optical and medical eye care. They are able to diagnose and treat most eye diseases and can prescribe both topical ...

https://en.wikipedia.org/wiki/Optometrist

Optical coherence tomography. *Electrodiagnosis: Electrooculography. *Electroretinography. *Electronystagmography. Eye ...

https://en.wikipedia.org/wiki/Ishihara_Test

Ballistic scanners (using ultrafast time gates) and optical coherence tomography (OCT) (using the interferometry principle) are ... The technique may also be referred to as diffuse optical tomography (DOT), near infrared optical tomography (NIROT) or ... and optical coherence tomography. Because light is an electromagnetic wave, similar phenomena occur in X-rays, microwaves, and ... Diffusive optical imaging[edit]. Diffuse optical imaging (DOI) is a method of imaging using near-infrared spectroscopy (NIRS) [ ...

https://en.wikipedia.org/wiki/Optical_imaging

Optical/Laser. *Optical tomography *Optical coherence tomography. *Confocal microscopy. *Endomicroscopy. *Orthogonal ... In contrast, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate ... Detectors coated with materials which scintillate when subjected to gamma rays are scanned with optical photon detectors and ... A special type of gamma camera is the SPECT (Single Photon Emission Computed Tomography). Another medical scintillography ...

https://en.wikipedia.org/wiki/Scintigraphy

... associated with accelerated eye aging by using deep learning to predict age from fundus and optical coherence tomography images ...

https://ru.wikipedia.org/wiki/Эпигенетические_часы

Optical coherence tomography. *Photorefractive keratectomy. *Photorejuvenation. *Soft-tissue laser surgery. Laser fusion. * ...

https://ml.wikipedia.org/wiki/ഗ്യാസ്_ലേസർ

Optical coherence tomography. *Eye care professional. *Eye disease. *Refractive error. *Accommodation. *Physiological Optics ... Validity of the Ferry-Porter law". Journal of the Optical Society of America A. 7 (4): 743-758. Bibcode:1990JOSAA...7..743T. ... Its center is shifted slightly away from the optical axis (laterally, by 5°=1.5 mm).[6] The macula in humans has a diameter of ...

https://en.wikipedia.org/wiki/Macula

Other gastroscopic modalities such as optical coherence tomography are being tested investigationally for similar applications. ... Computed tomography or CT scanning of the abdomen may reveal gastric cancer. It is more useful to determine invasion into ...

https://en.m.wikipedia.org/wiki/Stomach_cancer

Optical coherence tomography. *Eye care professional. *Eye disease. *Refractive error. *Accommodation. *Physiological Optics ... Of course, for most eye types, it is impossible to diverge from a spherical form, so only the density of optical receptors can ... Land, M.F. (1989). "The eyes of hyperiid amphipods: relations of optical structure to depth". Journal of Comparative Physiology ... This occurs because the ommatidia which one observes "head-on" (along their optical axes) absorb the incident light, while ...

https://en.wikipedia.org/wiki/Eye

"Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated ... It was included by the Optical Internetworking Forum for inclusion in 100 gigahertz optical networking standards. Optical ... The range of devices required on a chip includes low loss interconnect waveguides, power splitters, optical amplifiers, optical ... For instance, EFFECT Photonics develops affordable and high-performance optical communications solutions, such as SPF+ optical ...

https://en.wikipedia.org/wiki/Photonic_integrated_circuit

Directional atherectomy is an intravascular procedure guided by optical coherence tomography termed as lumivascular atherectomy ...

https://en.wikipedia.org/wiki/Atherectomy

Optical measurements of Ca2+ concentration showed that they respond strongly to the centrifugal motion (the outward motion from ... The sensitivity to motion coherence is assessed by measuring the ratio of 'signal' to 'noise' dots required to determine the ... 1993). "Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance ... The required ratio is called the motion coherence threshold. As in other aspects of vision, the observer's visual input is ...

https://en.wikipedia.org/wiki/Motion_perception

Optical Coherence Tomography, Field Analysis etc. Glaucoma Lacrimal (Tear Duct) Disorder Laser treatment Oculo-plastic Services ...

https://en.wikipedia.org/wiki/Layton_Rahmatullah_Benevolent_Trust

Coherence (physics) Coherence length Coherence theory (optics) Coherence time Coherent backscattering Coherent control Coherent ... Chaos in optical systems Chaos theory Chaotic Inflation theory Chaplygin gas Chapman function Chapman-Enskog theory Chapman- ... Conductivity of transparency Conductor gallop Cone beam computed tomography Configuration interaction Configuration space ... optical fiber) Core electron Core-mantle boundary Coriolis effect Coriolis field Coriolis-Stokes force Corium (nuclear reactor ...

https://en.wikipedia.org/wiki/Index_of_physics_articles_(C)

"Signal attenuation and box-counting fractal analysis of optical coherence tomography images of arterial tissue". Biomedical ...

https://en.wikipedia.org/wiki/Fractal_dimension

The retinal nerve fiber layer can be assessed with imaging techniques such as optical coherence tomography, scanning laser ... 12 (9). Aptel F, Dumas S, Denis P (2009). "Ultrasound biomicroscopy and optical coherence tomography imaging of filtering blebs ...

https://en.wikipedia.org/wiki/Glaucoma

... facilitating control of color using optical coherence tomography. Structural control means that a single fiber will always show ... The ability to vary reflectivity to different wavelengths of light could also lead to efficient optical switches that could ... efficient optical switches and low-reflectance glass. In his 1665 book Micrographia, Robert Hooke described the "fantastical" ... or they are partly caused by optical effects due to the scattering, diffraction or unequal refraction of the light rays. ...

https://en.wikipedia.org/wiki/Structural_coloration

Ballistic scanners (using ultrafast time gates) and optical coherence tomography (OCT) (using the interferometry principle) are ... Medical optical imaging Lihong V. Wang; Hsin-i Wu (26 September 2012). Biomedical Optics: Principles and Imaging. John Wiley & ... Photons that are slightly scattered, retaining some degree of coherence, are referred to as snake photons. The aim of ballistic ... non-ballistic photons are used, such as time of flight through coherence-gated imaging, collimation, wavefront propagation, and ...

https://en.wikipedia.org/wiki/Ballistic_photon

Treacy, M. M. J.; Gibson, J. M. (1996-03-01). "Variable Coherence Microscopy: a Rich Source of Structural Information from ... Lee, Z.; Kaiser, U.; Rose, H. (January 2019). "Prospects of annular differential phase contrast applied for optical sectioning ... Eggeman, Alexander S.; Krakow, Robert; Midgley, Paul A. (2015-06-01). "Scanning precession electron tomography for three- ...

https://en.wikipedia.org/wiki/4D_scanning_transmission_electron_microscopy

"Performance and scalability of Fourier domain optical coherence tomography acceleration using graphics processing units". ... "Performance and scalability of Fourier domain optical coherence tomography acceleration using graphics processing units". ...

https://en.wikipedia.org/wiki/Lesley_Shannon

Free electron laser Laser hair removal IPL Photobiomodulation Optical diagnostics, for example optical coherence tomography of ... optical diagnostics, cardiology, circadian rhythm sleep disorders and oncology. A branch of photomedicine is light therapy in ...

https://en.wikipedia.org/wiki/Photomedicine

Fluorescent angiogram of a 5-year-old boy with HJMD Optical coherence tomography of a 5-year-old boy with HJMD Fundoscopy, left ... retinal scanning and optical coherence tomography; electrophysiological examinations such as electroretinography (ERG) or ...

https://en.wikipedia.org/wiki/Hypotrichosis_with_juvenile_macular_dystrophy

... in vivo imaging of cortical vasculature via fluorescence microscopy and 3D optical coherence tomography. Researchers at Monash ... "Optical antennas trap and control light with the help of graphene". May 23, 2014. Ren, Xingang; Sha, Wei E. I.; Choy, Wallace C ... Optical transparency was greater than 90%. Applications demonstrated include optogenetic activation of focal cortical areas, ... Szondy, David (January 31, 2016). "Graphene optical lens a billionth of a meter thick breaks the diffraction limit". newatlas. ...

https://en.wikipedia.org/wiki/Potential_applications_of_graphene

Proscurin, Sergei; Meglinski, Igor (2007). "Optical coherence tomography imaging depth enhancement by superficial skin optical ... Meglinski, Igor; Buranachai, Chitannon; Terry, Leon (2010). "Plant Photonics: Use of Optical Coherence Tomography to monitor ... pioneering the enhancement of probing depth for confocal reflectance microscopy and Optical Coherence Tomography (OCT). This ... Fellows of the Optical Society, Fellows of SPIE, Fellows of the Institute of Physics, Senior Members of the IEEE, Optical ...

https://en.wikipedia.org/wiki/Igor_Meglinski

"Balanced detection for spectral domain optical coherence tomography". Optics Express. 21 (16): 19280-19291. doi:10.1364/OE. ... to the specularly reflected light that is assessed in more conventional imaging methods such as optical coherence tomography. ... Multiple scattering low coherence interferometry (ms/LCI) is an imaging technique that relies on analyzing multiply scattered ... As in traditional OCT, the beam interference coherence gates the light in order to filter out photons that have not traveled a ...

https://en.wikipedia.org/wiki/Multiple_scattering_low_coherence_interferometry

Other modalities, including optical coherence tomography are also under development for dental imaging. Oral or dental ... Machoy M, Seeliger J, Szyszka-Sommerfeld L, Koprowski R, Gedrange T, Woźniak K (2017). "The Use of Optical Coherence Tomography ... Oral and maxillofacial imaging includes cone beam computerized tomography, multislice computerized tomography, magnetic ... cone beam computerized tomography, multislice computerized tomography and magnetic resonance imaging of the maxillofacial ...

https://en.wikipedia.org/wiki/Oral_and_maxillofacial_radiology

"Optical coherence tomography using a continuous-wave, high-power, Raman continuum light source". Optics Express. The Optical ... "Ultrahigh-resolution optical coherence tomography using continuum generation in an air-silica microstructure optical fiber". ... including optical coherence tomography, frequency metrology, fluorescence lifetime imaging, optical communications, gas sensing ... Schnatz, H.; Hollberg, L.W. (2003). "Optical frequency combs: From frequency metrology to optical phase control". IEEE Journal ...

https://en.wikipedia.org/wiki/Supercontinuum

... of Cystoid Macular Edema after Cataract Surgery in Patients with and without Uveitis Using Optical Coherence Tomography". ...

https://en.wikipedia.org/wiki/Irvine–Gass_syndrome

With his work he has made significant contributions to development of the Optical Coherence Tomography (OCT) method and ... "Real-time in vivo imaging by high-speed spectral optical coherence tomography". Opt. Express. 28 (19): 1745-1747. Bibcode: ... Wojtkowski is a Fellow of the Optical Society of America, and since 2016 he is a corresponding member of the Polish Academy of ... which he later led until 2016 as the Optical Biomedical Imaging Group. After succeeding in the 2015 EraChair competition, ...

https://en.wikipedia.org/wiki/Maciej_Wojtkowski

Review the basic principles of optical coherence tomography and its application in a variety of neurological disorders, ... Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-resolution in vivo imaging of ... Optical coherence tomography (OCT) is an efficient, non-invasive imaging modality that utilizes light interferometry to ... In this review, we outline the basic principles of optical coherence tomography and discuss its application to managing ...

https://www.medscape.com/viewarticle/986444_1

The OCT is the first instrument that allows doctors to see a direct cross-sectional image of the retina. The OCT is similar to a CT scan of internal organs, except it doesnt use X-rays. Instead a beam of light is used to rapidly scan the eye and generate an image without ever touching the patient. This painless scan takes less than 10 minutes. Since there is no patient contact, patient comfort is improved and the test is performed in less time. These images are critical to assess the anatomical structures of the eye and any retinal changes.. This scan can provide practitioners with a guidepost to determine how a specific patient s retinal nerve fiber layer compares to a normal range on the instruments database. Therefore, changes in the thickness of the retinal nerve fiber layer could be an indication of early glaucomatous changes. Besides glaucoma, the OCT analysis the appearance of various changes in the posterior segment of the eye. These include diabetic retinopathy, macular holes, ...

https://www.ferris.edu/optometry/patient-care/special-testing/Optical-Coherence-Tomography-.htm

... Surv Ophthalmol. 2012 Sep;57(5):389-414. doi: ... In line with these advances, a new imaging modality-optical coherence tomography (OCT)-has emerged as an essential adjunct for ...

https://pubmed.ncbi.nlm.nih.gov/22898648/

... the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical ... In this work, a mid-infrared spectral-domain optical coherence tomography system operating at a central wavelength of 4 µm and ... In doing so, the first practical mid-infrared optical coherence tomography system is demonstrated, with immediate applications ... Using longer wavelengths of light in Optical Coherence Tomography (OCT) imaging allows deeper penetration in highly scattering ...

https://www.nature.com/articles/s41377-019-0122-5??utm_source=other_website&utm_medium=display&utm_content=mpu&utm_campaign=JRCN_2_JG_Xmol_tracker&error=cookies_not_supported&code=e31c6392-efe9-4180-b521-268bb8972832

Patterns of Optical Coherence Tomography Imaging in Preperimetric Open Angle Glaucoma: A Comparative Study With Young-Age-Onset ... optical coherence tomography (OCT)\r, primary angle closure suspect (PACS)\r, anterior chamber depth (ACD)\r, intraocular ... Relationship Between Optical Coherence Tomography and Anterior Chamber Depth After Pupillary Dilation in Primary Angle Closure ... Relationship Between Optical Coherence Tomography and Anterior Chamber Depth After Pupillary Dilation in Primary Angle Closure ...

https://journals.lww.com/glaucomajournal/Abstract/2022/11000/Relationship_Between_Optical_Coherence_Tomography.11.aspx

Full-Field Optical Coherence Tomography (FF-OCT or Full-Field OCT) is ideally suited for the in vitro examination of tissue ... Measurement systems for optical coherence tomography (OCT) therefore offer great diagnostic added value due to their high ... www.ipt.fraunhofer.de/en/Competencies/Productionqualityandmetrology/Productionmetrology/full-field-optical-coherence-tomography ... Fraunhofer Institute for Production Technology IPT - Full-Field Optical Coherence Tomography. Online in Internet; URL: https:// ...

https://www.ipt.fraunhofer.de/en/Competencies/Productionqualityandmetrology/Productionmetrology/full-field-optical-coherence-tomography.html

Affordable Optical Coherence Tomography (OCT) Imaging System Provides High Resolution Imaging. Features axial resolutions of ... introduces a new Optical Coherence Tomography (OCT) Imaging System from Lumedica, the OQ LabScope. This all-in-one, high ... December 14, 2017, Barrington, N.J. - Edmund Optics® (EO), the premier provider of optical components, ... has earned it the position of the worlds largest supplier of off-the-shelf optical components. Customers can purchase items by ...

https://www.labmanager.com/product-news/affordable-optical-coherence-tomography-oct-imaging-system-provides-high-resolution-imaging-5494

Optics for Optical Coherence Tomography (OCT). ON DEMAND WEBINAR. See All Webinars ... Adam Wax, Founder of Lumedica, for our next webinar on Optical Coherence Tomography (OCT). Topics discussed will include: an ... He is a fellow of the Optical Society of America, SPIE, and AIMBE and is inventor on 19 US patents. He currently serves as the ... Join us for a demonstration on selecting the proper optical components for your OCT system for non-invasive, high-resolution ...

https://www.edmundoptics.com/knowledge-center/webinars/optics-for-optical-coherence-tomography/?utm_medium=website&utm_source=webinar&utm_campaign=optical_coherence_tomography_webinar&utm_content=event-page&utm_term=life_sciences

This study instends to investigate the potential of Optical Coherence Tomography Angiography (OCTA) device to image and ... Optical Coherence Tomography Angiography; VD: Vessel Density; CoNV: Corneal Neovascularization; OCT: Optical Coherence ... Optical coherence tomography angiography: a review of current and future clinical applications. Graefes Arch Clin Exp ... Comparison of Optical Coherence Tomography Angiography to Indocyanine Green Angiography and Slit Lamp Photography for Corneal ...

https://www.researchsquare.com/article/rs-1025402/v1

Publications: Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography, OCT NEWS, Feature of the ... Publications: Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography, Optics Express, 2010, 18(10 ... Synchronized Femtosecond Fiber Lasers for Optical Coherence Tomography (OCT) Using ECOPS to speed up TD-OCT measurements OCT ... Publications: Optical Coherence Tomography with fs Fiber Lasers and ECOPS, Laser Magazin, 2009, 2-3, pp. 62-94. ...

https://www.toptica.com/applications/ultrafast-studies/oct

3D thickness measurement using pulse-driven optical coherence tomography based on wavelet transform Author(s): Takamasa Suzuki ... In this study, we propose a spectral-domain optical coherence tomography (OCT) method that employs pulse irradiation to capture ... SPIE 11102, Applied Optical Metrology III, 111021A (3 September 2019); doi: 10.1117/12.2534005. Show Author Affiliations. ...

https://spie.org/Publications/Proceedings/Paper/10.1117/12.2534005

Diagnostic Accuracy of Endobronchial Optical Coherence Tomography for the Microscopic Diagnosis of Usual Interstitial Pneumonia ... Diagnostic Accuracy of Endobronchial Optical Coherence Tomography for the Microscopic Diagnosis of Usual Interstitial Pneumonia ...

https://www.thoracic.org/members/assemblies/assemblies/rcmb/journal-club/diagnostic-accuracy-of-endobronchial-optical-coherence-tomography.php

... be alluded to as diffuse optical tomography close to infrared optical tomography or fluorescence diffuse optical tomography, ... Ballistic scanners utilizing ultrafast time entryways and optical intelligence tomography utilizing the interferometry ... and optical rationality tomography. Since light is an electromagnetic wave, comparative marvels happen in Xbeams, microwaves, ... Clinical optical imaging is the utilization of light as an investigational imaging strategy for clinical applications. Models ...

https://www.alliedacademies.org/articles/optical-coherence-tomography-oct-17616.html

Global optical coherence tomography market is projected to account for noteworthy sales of USD 1.8 Billion by 2024. ... Optical Coherence Tomography Market Overview. Optical coherence tomography is referred to a non-invasive imaging diagnostic ... Time domain Optical Coherence Tomography (TDOCT). *Spatially Encoded Frequency Domain Optical Coherence Tomography *Spectral ... However, high cost of optical coherence tomography is expected to hinder the growth of optical coherence tomography market ...

https://www.researchnester.com/reports/optical-coherence-tomography-market/558

EP-2675338-B1 chemical patent summary.

https://pubchem.ncbi.nlm.nih.gov/patent/EP-2675338-B1

Purpose To describe en face swept-source optical coherence tomography (SS-OCT) findings in the retinal pigment epithelium (RPE ... En face swept-source optical coherence tomography in neovascular age-related macular degeneration ... En face swept-source optical coherence tomography in neovascular age-related macular degeneration ...

https://bjo.bmj.com/content/99/9/1260

International Society for Optical Engineering, 2nd Canterbury Conference on Optical Coherence Tomography, Canterbury, United ... Phase estimation for global defocus correction in optical coherence tomography. Mikkel Jensen, Niels Møller Israelsen, Adrian ... Phase estimation for global defocus correction in optical coherence tomography. Mikkel Jensen (Speaker), Niels Møller Israelsen ... keywords = "Optical coherence tomography, Angular spectrum method, Defocus correction",. author = "Mikkel Jensen and Israelsen ...

https://orbit.dtu.dk/en/publications/phase-estimation-for-global-defocus-correction-in-optical-coheren

Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical ... Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. Journal of Pharmaceutical Sciences, 106 ... As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some ...

https://eprints.lancs.ac.uk/id/eprint/86926/

Enhanced depth imaging optical coherence tomography (EDI-OCT), Heterogeneous uveitis, Hyper-reflective foci, Hypo-reflective ... PURPOSE: Enhanced depth imaging (EDI) optical coherence tomography (OCT) has emerged as a novel tool for qualitative and ... Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or ... Morphometric features on enhanced depth imaging optical coherence tomography scans in idiopathic posterior uveitis or ...

https://discovery.ucl.ac.uk/id/eprint/10042598/

Username or E- ...

http://www.octnews.org/userauth/login/?next=/articles/10466432/automatic-characterisation-of-human-atheroscleroti/comments/thread/21%2C10466432/reply/21%2C10466432/

As SOCM constitutes the microscopy counterpart to spectral optical coherence tomography (SOCT), the developed processing ... present an application of massively parallel processing of quantitative flow measurements data acquired using spectral optical ... coherence microscopy (SOCM). The need for massive signal processing of these particular datasets has been a major hurdle for ... Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography.. ...

https://data.mendeley.com/datasets/mdkc8nnw8w

Molecular optical coherence tomography contrast enhancement and imaging. In: Drexler W Fujimoto JG eds. Optical Coherence ... Evaluation of Contrast Agents for Enhanced Visualization in Optical Coherence Tomography Justis P. Ehlers; Preeya K. Gupta; ... time domain optical coherence tomography. Opt Express. 2003;11:889-894. [CrossRef] [PubMed] ... Huang D Swanson EA Lin CP . Optical coherence tomography. Science. 1991;254:1178-1181. [CrossRef] [PubMed] ...

https://iovs.arvojournals.org/article.aspx?articleid=2127068

Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. ... Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. Journal ... Optical coherence tomography (OCT) is a depth-resolved, noninvasive, non-destructive imaging modality, the use of which has yet ... The optical and histological results showing cardiovascular microstructures such as myocardium, the cardiac jelly, and ...

https://scholars.duke.edu/display/pub646283

Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography ... Intravitreal cysticercosis with full thickness macular hole: management outcome and intraoperative optical coherence tomography ... a case of live intravitreal cysticercosis with a FTMH along with its management and intraoperative optical coherence tomography ...

https://casereports.bmj.com/content/2017/bcr-2016-218645.abstract

... applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired ... applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired ... circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography. ...

https://escholarship.org/uc/item/60t365jn

Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography ... This study demonstrates the use of optical coherence tomography (OCT) to simultaneously characterize the roughness of the ... 3D thickness map, coating, optical coherence tomography, roughness, solid oral dosage form, Pharmacy and materia medica, ... Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography. International Journal of ...

https://strathprints.strath.ac.uk/64133/

... Process monitoring in the Additive Manufacturing process has ... Optical coherence tomography (OCT) has been utilised for in-line monitoring, with analysis of surfaces as well as internal ... Optical coherence tomography used in process monitoring of Additive Manufacturing. September 1, 2016. ... FH) Christian Wolf, have for the first time ever applied the medical imaging technique of optical coherence tomography to ...

https://www.metal-am.com/optical-coherence-tomography-used-process-monitoring-additive-manufacturing/

... resolution Optical Coherence Tomography (OCT) and Forward-Looking IVUS systems and catheters. Currently, more than 4,700 ... Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging. 200kHz High ... MEMs-based optical and mechanical components, optical fiber design, manipulation and assembly, light sources used in optical ... This approach to optical engines builds on over 10 years of Axsuns core integrated light source technology and is protected by ...

http://www.ptca.org/news/2009/1204_VOLCANO.html

... stress relaxation optical coherence straingraphy (SR-OCSA). The purpose of this study was to establish an approach for ... We developed an optical coherence tomography-based strain rate tomography method: ... as determined by optical coherence tomography-based strain rate tomography ... Stress relaxation optical coherence straingraphy (SR-OCSA) system. a Illustration of the experimental apparatus. b Photograph ...

https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-019-2789-4/figures/1

Optical coherence tomography angiography in diabetes and diabetic retinopathy. Authors: Chua, Jacqueline. Sim, Ralene. Tan, ... Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by ... Optical coherence tomography angiography in diabetes and diabetic retinopathy. Journal of Clinical Medicine, 9(6), 1723-. https ...

https://dr.ntu.edu.sg/handle/10356/148787

In this work, a mid-infrared spectral-domain optical coherence tomography system operating at a central wavelength of 4 µm and an axial resolution of 8.6 µm is demonstrated. (nature.com)
In this study, we propose a spectral-domain optical coherence tomography (OCT) method that employs pulse irradiation to capture an interferogram and continuous wavelet transform (CWT) for data analysis. (spie.org)
Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography. (escholarship.org)
The purpose was to create a three-dimensional (3-D) model of circumferential aqueous humor outflow (AHO) in a living human eye with an automated detection algorithm for Schlemm's canal (SC) and first-order collector channels (CC) applied to spectral-domain optical coherence tomography (SD-OCT). Anterior segment SD-OCT scans from a subject were acquired circumferentially around the limbus. (escholarship.org)
Kanngießer, Jonas Peter: Wavefront shaping approaches for spectral domain optical coherence tomography. (uni-hannover.de)
To compare the penetration of riboflavin using a microscope-integrated real time spectral domain optical coherence tomography (ZEISS OPMI LUMERA 700 and ZEISS RESCAN 700) in keratoconus patients undergoing accelerated collagen crosslinking (ACXL) between epithelium on (epi-on) and epithelium off (epi-off). (maastrichtuniversity.nl)
B, Spectral-domain optical coherence tomography scan shows diffuse retinal thickening with cystic areas of low reflectivity predominantly in the inner nuclear and outer plexiform layers. (aao.org)
Spectral-Domain Optical Coherence Tomography Findings as Prognostic Factors in Patients with Acute Central Serous Chorioretinopathy. (dergisi.org)
Choroidal neovascularization subtype and activity were evaluated using spectral domain optical coherence tomography, infrared light, fundus autofluorescence, fluorescein angiography (FA), and indocyanine green angiography (ICGA). (unimi.it)
RESULTS: The interobserver k regarding the types of CNV was 0.69 for multiimaging, 0.63 for spectral domain optical coherence tomography, 0.43 for FA, and 0.46 for ICGA. (unimi.it)
The k values for interobserver for retreatment decision were 0.77 for multiimaging, 0.88 for spectral domain optical coherence tomography, 0.61 for infrared, 0.37 for fundus autofluorescence, 0.25 for FA, and 0.23 for ICGA. (unimi.it)

This study instends to investigate the potential of Optical Coherence Tomography Angiography (OCTA) device to image and describe quantitatively the vascularization in eyes diagnosed with herpetic leucoma and to discuss and review the usefulness of this technique in this pathology. (researchsquare.com)
All eyes underwent anterior segment Slit-Lamp photography (SLP), and Optical Coherence Tomography Angiography (OCT) with en-face, b-scans and c-scans imaging. (researchsquare.com)
Purpose To describe en face swept-source optical coherence tomography (SS-OCT) findings in the retinal pigment epithelium (RPE) and choroid and to correlate them with fluorescein angiography (FA) and/or indocyanine green angiography (ICGA) in neovascular age-related macular degeneration (AMD). (bmj.com)
Conclusions En face SS-OCT is a rapid, non-invasive, high-resolution, promising technology, which allows a complementary study to angiography of neovascular AMD. (bmj.com)
There is a correlation between angiography and en face SS-OCT images in neovascular AMD. (bmj.com)
Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood cells. (ntu.edu.sg)
Methods: The "Eye Determinants of Cognition" (EyeDOC) study recruited a biracial, population-based sample of participants from two sites: Jackson, MS, and Washington Co, MD. Optical coherence tomographic angiography (OCTA) was used to capture vessel density (VD) from a 6 × 6 mm scan of the macula in several vascular layers from 2017 to 2019. (elsevier.com)
Important aspects of workup regarding diabetic retinopathy include fasting glucose and hemoglobin A1c, fluorescein angiography, optical coherence tomography, and B-scan ultrasonography. (medscape.com)
The investigations included complete slit lamp and fundoscopy examinations, automated visual field analysis, Amsler charting, fundus fluorescein angiography and optical coherence tomography. (who.int)
Purpose: The aim of this study was to evaluate 1-year quantitative changes in specific inflammatory parameters on optical coherence tomography (OCT) / optical coherence tomography angiography (OCTA) in diabetic macular edema (DME) treated with subthreshold micropulse laser (SMPL). (elsevier.com)
The optical coherence tomography and the optical coherence tomography-angiography en face (Figs. (canadianjournalofophthalmology.ca)

The global optical coherence tomography market is expected to grow at a CAGR of 10.9% over the forecast period i.e. 2017-2024. (researchnester.com)
Moreover, the global optical coherence tomography market is projected to account for noteworthy sales of USD 1.8 Billion by 2024. (researchnester.com)
The global optical coherence tomography market is segment into type, device type, application, technology, end user and region. (researchnester.com)
The global Optical Coherence Tomography market research report offers extensive statistical analysis to impart a deeper understanding of the Optical Coherence Tomography industry and the changing dynamics of the business sphere. (sngine.com)
The report on the global Optical Coherence Tomography market discusses in depth the current and emerging trends of the industry and discusses in detail the advancements in the technological and product sector. (sngine.com)

The results of techniques like polarization-sensitive optical coherence tomography PS-OCT , scanning laser polarimetry, or polarization microscopy are contradictory. (unican.es)

abstract = "In this work we investigate three techniques for estimation of the non-linear phase present due to defocus in opticalcoherence tomography, and apply them with the angular spectrum method. (dtu.dk)

Nevertheless, the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical components in this spectral region, resulting in slow acquisition, low sensitivity, and poor axial resolution. (nature.com)
We present an application of massively parallel processing of quantitative flow measurements data acquired using spectral optical coherence microscopy (SOCM). (mendeley.com)
As SOCM constitutes the microscopy counterpart to spectral optical coherence tomography (SOCT), the developed processing procedure can be applied to both imaging modalities. (mendeley.com)

Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography. (mendeley.com)
Microscopy and coherence tomography systems, LIDAR and LADAR, fiber-optic sensors. (mit.edu)

Since its first in vivo use for the retina, optical coherence tomography (OCT) imaging has revolutionized the ability to evaluate the eye and its structures with unprecedent resolution. (researchsquare.com)
Purpose: To identify the pathologies of the vitreoretinal interface by Optical Coherence Tomography OCT of the retina in Lomé. (scirp.org)
Cross-sectional tomographs of the retina profiling optical reflectivity in a thin, optical slice of tissue are obtained with a longitudinal resolution of 10 μm. (nyu.edu)
Optical coherence tomography also was used to evaluate the vitreoretinal interface in patients' fellow eyes and was able to detect small separations of the posterior hyaloid from the retina. (nyu.edu)
Optical coherence tomography (OCT) uses light to generate a cross-sectional image of the retina. (medscape.com)
Optical coherence tomography (OCT) captures reflected light from retinal structures to create a cross-sectional image of the retina, like histologic sections as seen with a light microscope. (medscape.com)

Optical coherence tomography (OCT) has been established as one of the most successful and significant optical techniques for biophotonics and clinical biomedical imaging, most notably within the field of ophthalmology. (nature.com)
Originally developed for ophthalmology, Optical Coherence Tomography (OCT) now spreads over to a variety of applications. (toptica.com)
Optical coherence tomography has emerging applications in ophthalmology, oncology, dermatology and others. (researchnester.com)
First described in 1991, 1 optical coherence tomography (OCT) has improved ultrastructural imaging and diagnosis in ophthalmology and in multiple other fields, including cardiology, dermatology, gastroenterology, and urology. (arvojournals.org)

Anterior chamber depth (ACD) change after pupillary dilation is correlated with lens vault (LV) and anterior chamber width (ACW), as observed by swept-source optical coherence tomography (SS-OCT) at both horizontal and vertical scans in patients with primary angle closure suspect and cataract. (lww.com)
OCT scans of a tape roll acquired with electronically controlled optical sampling (ECOPS) (Courtesy of Stefan Kray). (toptica.com)
Deep Learning Based Staging of Bone Lesions From Computed Tomography Scans. (cdc.gov)

Objective: To determine the repeatability and reproducibility of retinal thickness measurements with the fast macular thickness mapping protocol of Stratus optical coherence tomography. (elsevier.com)
Conclusion: With the fast macular thickness mapping protocol of Stratus ocular coherence tomography, our results indicate that retinal thickness measurements in dilated and undilated eyes of healthy subjects and diabetic patients with CSME are repeatable and reproducible. (elsevier.com)
Evaluation of intraocular pressure, choroidal and retinal thickness measurements using optical coherence tomography in non - diabetic haemodialysis patients. (akiugydytojai.lt)

In doing so, the first practical mid-infrared optical coherence tomography system is demonstrated, with immediate applications in real-time non-destructive testing for the inspection of defects and thickness measurements in samples that exhibit strong scattering at shorter wavelengths. (nature.com)
Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical tablets and pellets directly. (lancs.ac.uk)
Optical coherence tomography was used to examine 49 patients with the clinical diagnosis of idiopathic full-thickness macular hole, impending macular hole, epimacular membrane with macular pseudohole, or partial-thickness hole. (nyu.edu)
Even with these limitations we conclude that the data presented in this study represent an important first step to develop a noninvasive optical tool that can reliably distinguish between superficial-partial and deep-partial thickness burn wounds. (careersfromscience.org)

As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some pharmaceutical coatings may not be measurable altogether. (lancs.ac.uk)
Methods: Optical coherence tomography is analogous to ultrasound except that optical rather than acoustic reflectivity is measured. (nyu.edu)
Transmission Systems - Parallel-plate optical waveguide, modes (ray and wave-optics methods). (mit.edu)
However, most of these methods require sophisticated modeling of optical and acoustic transportations, producing challenges for real-time imaging. (cdc.gov)
Integration of LSI and other optical imaging methods such as Spatial Frequency Domain Imaging [20] is expected to yield a device that enables robust characterization of the severity of burn wounds. (careersfromscience.org)

Axsun believes this proprietary optical engine design raises the bar on imaging speed and overcomes fundamental limitations of laser-based designs for swept source OCT light sources. (ptca.org)
Here, we present a combined photoacoustic remote sensing (PARS) microscope and swept source optical coherence tomography (SS-OCT) system designed to circumvent these diagnostic limitations. (arxiv.org)
Dubey D, Shanmugam M, Ramanjulu R, Mishra KC, Doshi B. Swept source optical coherence tomography in globe perforation. (who.int)

Purpose: To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error. (elsevier.com)
Advanced Imaging for Glaucoma Study Group 2016, ' Regression analysis of optical coherence tomography disc variables for glaucoma diagnosis ', Journal of Glaucoma , vol. 25, no. 8, pp. 634-642. (elsevier.com)

Optical coherence tomography (OCT) is an efficient, non-invasive imaging modality that utilizes light interferometry to visualize and quantify neural tissue microstructure with high resolution, accuracy, and reproducibility. (medscape.com)
OCT relies on low coherence interferometry utilizing spectrally broad light sources like superluminescent diodes or femtosecond lasers, since the resolution of OCT is determined by the inverse bandwidth of the light source. (toptica.com)
Ballistic scanners utilizing ultrafast time entryways and optical intelligence tomography utilizing the interferometry guideline are only two of the wellknown imaging frameworks that depend on ballistic photon discovery to make diffraction-restricted pictures. (alliedacademies.org)
Andrei V. Zvyagin, Elwyn D. J. Smith, and David D. Sampson, "Delay and dispersion characteristics of a frequency-domain optical delay line for scanning interferometry," J. Opt. (optica.org)
The reflective frequency-domain optical delay line employing a diffraction grating, a lens, and a tiltable mirror has emerged as a device particularly suitable for interferometry and optical coherence tomography. (optica.org)

Optical coherence tomography allows for various measurements of skin but the utility of the device in determining properties of normal and wounded skin in diabetic patients is unknown. (jfas.org)

Optical Coherence Tomography with fs Fiber Lasers and ECOPS , Laser Magazin, 2009, 2-3, pp. 62-94. (toptica.com)
Axsun is a leading developer and supplier of tunable lasers for OCT imaging, offering the highest speed integrated optical products on the market today," explained Dale Flanders, President of Axsun. (ptca.org)

In terms of geography, North America is projected to lead the market of optical coherence tomography during the forecast period aided by U.S. In addition to this, the growth of North America optical coherence tomography market is attributed to various factors such as presence of major key vendors along with growing research and development activities related to imaging diagnostic products. (researchnester.com)

Therefore, quantitative PAT, such as absolute oxygen saturation (sO 2 ) quantification, requires knowledge of the local optical fluence, which can be estimated only through invasive measurements or sophisticated modeling of light transportation. (cdc.gov)

In line with these advances, a new imaging modality-optical coherence tomography (OCT)-has emerged as an essential adjunct for the diagnosis and monitoring of patients with AMD. (nih.gov)
The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities that enable disease diagnosis from living patients without excising tissues from the body. (photonicsjobs.com)

The procedure may likewise be alluded to as diffuse optical tomography close to infrared optical tomography or fluorescence diffuse optical tomography, contingent upon the utilization.In neuroscience, utilitarian estimations made utilizing NIR frequencies, DOI procedures may characterize as practical close to infrared spectroscopy. (alliedacademies.org)

December 14, 2017, Barrington, N.J. - Edmund Optics® (EO), the premier provider of optical components, introduces a new Optical Coherence Tomography (OCT) Imaging System from Lumedica, the OQ LabScope. (labmanager.com)
Becca Charboneau, Solutions Engineer for Edmund Optics, will be joined by Dr. Adam Wax, Founder of Lumedica, for our next webinar on Optical Coherence Tomography (OCT). Topics discussed will include: an overview of OCT, key applications, and how to select the proper optics for your OCT system. (edmundoptics.com)
She joined Edmund Optics in 2021 and has been working closely with our life science customers to provide them with custom optical solutions based around their system needs. (edmundoptics.com)

He is a fellow of the Optical Society of America, SPIE, and AIMBE and is inventor on 19 US patents. (edmundoptics.com)

The findings were confirmed on anterior segment optical coherence tomography (ASOCT) [Figure 1] c. (ijoreports.in)

Optical coherence tomography (OCT) is a depth-resolved, noninvasive, non-destructive imaging modality, the use of which has yet to be fully realized in developmental biology. (duke.edu)
Conclusion: Optical coherence tomography appears potentially useful as a new, noninvasive, diagnostic technique for visualizing and quantitatively characterizing macular holes and assessing fellow eyes of patients with a macular hole. (nyu.edu)

Optical coherence tomography is a non-invasive, cost-efficient technique that provides high-resolution in vivo imaging of retinal tissue. (medscape.com)
Full-Field Optical Coherence Tomography (FF-OCT or Full-Field OCT) is ideally suited for the in vitro examination of tissue samples as well as for the in vivo examination of patient tissue. (fraunhofer.de)
High-resolution and rapid in-vitro and in-vivo tissue diagnostics for pre- and intraoperative use in ENT diseases for faster treatment and avoidance of tissue sampling through optical biopsies. (fraunhofer.de)
The fellowship will focus on high resolution OCT imaging devices, including development of novel optical techniques, engineering of in vivo endoscopic probes, and translation to clinical use. (photonicsjobs.com)
have recently published a paper investigating the elastic properties of human skin in vivo via the optical coherence tomography. (cdc.gov)

In this regard, OCT stands out from other traditional NDT techniques, such as high-frequency laser ultrasonic (LUS) imaging, terahertz (THz) imaging, and micro X-ray computed tomography (μCT), each with its own advantages and disadvantages. (nature.com)
Join us for a demonstration on selecting the proper optical components for your OCT system for non-invasive, high-resolution imaging. (edmundoptics.com)
Publications: Nevet, A., Michaeli, T. & Orenstein, M. Second-order optical coherence tomography: deeper and turbulence-free imaging . (toptica.com)
Clinical optical imaging is the utilization of light as an investigational imaging strategy for clinical applications. (alliedacademies.org)
Optical imaging frameworks might be partitioned into diffusive and ballistic imaging frameworks. (alliedacademies.org)
The longing for an indicative optical imaging methodology has spurred the advancement of picture remaking techniques including arrangement of the backwards issue. (alliedacademies.org)
Optical coherence tomography is referred to a non-invasive imaging diagnostic test. (researchnester.com)
PURPOSE: Enhanced depth imaging (EDI) optical coherence tomography (OCT) has emerged as a novel tool for qualitative and quantitative choroidal assessment in posterior uveitis. (ucl.ac.uk)
Historically, common imaging modalities, such as magnetic resonance imaging (MRI) and computed tomography (CT), have used agents such as gadolinium or iodinated contrast to further improve diagnostic capabilities and visualization of pathology and tissue structure. (arvojournals.org)
Optical coherence tomography: a new high-resolution imaging technology to study cardiac development in chick embryos. (duke.edu)
FH) Christian Wolf, have for the first time ever applied the medical imaging technique of optical coherence tomography to monitor the Additive Manufacturing process. (metal-am.com)
We acquired Axsun for their significant expertise spanning a broad range of disciplines within optics and photonics - including the design and manufacture of MEMs-based optical and mechanical components, optical fiber design, manipulation and assembly, light sources used in optical imaging and spectroscopy, and sophisticated electronics and electro-mechanical systems needed to support complete solutions. (ptca.org)
Optical coherence tomography imaging of normal, chronologically aged, photoaged and photodamaged skin: a systematic review. (jfas.org)
Optical coherence tomography (OCT) enables sub-surface three dimensional imaging with micrometer resolution. (uni-hannover.de)
First applications to optical coherence tomography were shown to extend the penetration depth as well as to improve the signal-to-noise ratio when imaging biological tissue. (uni-hannover.de)
Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging? (elsevier.com)
Dive into the research topics of 'Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging? (elsevier.com)
Adaptive Optical Systems - Wavefront measurement systems, sharpness function, Unconventional AO, wavefront correctors, stellar imaging and star-wars applications. (mit.edu)
Keyword pattern analysis showed that magnetic resonance imaging, optical coherence tomography, expanded disability status, demyelination, and epidemiology were the major themes of multiple sclerosis research in Arab countries. (who.int)
Photoacoustic tomography (PAT) is a hybrid imaging technique that has broad preclinical and clinical applications. (cdc.gov)
Association of cognitive impairment with optical coherence tomography and magnetic resonance imaging changes in multiple sclerosis", 31st CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MULTIPLESCLEROSIS, 7 - 10 October 2015, Barcelona, Spain. (akiugydytojai.lt)
Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic, sensing, detection and imaging needs of our OEM and end-user customers. (photonics.com)
We offer state of the art testing including but not limited to Optos imaging, Visual Fields, OCT (Optical coherence tomography) and MPOD (Macular pigment testing) and also the most fashionable and trendiest frames available. (opticalnearme.com)

This study demonstrates the use of optical coherence tomography (OCT) to simultaneously characterize the roughness of the tablet core and coating of pharmaceutical tablets. (strath.ac.uk)
Vertical B-scan, en-face and 3-D images were produced to calculate surface and dermal-epidermal junction roughness, the optical attenuation coefficient, a measure of light absorption and scattering, and blood flow metrics. (jfas.org)

CONCLUSION: Optical coherence tomography and infrared evaluations of CNV activity were reproducible and strongly associated with multiimaging, whereas FA and ICGA evaluations showed poor reproducibility. (unimi.it)

SPIE - International Society for Optical Engineering, 2017. (dtu.dk)

Retinal pathology as a new biomarker in MS: evaluation by optical coherence tomograph. (akiugydytojai.lt)

Measurement systems for optical coherence tomography (OCT) therefore offer great diagnostic added value due to their high resolution and measurement speed. (fraunhofer.de)

Advances in optical coherence tomography in dermatology-a review. (jfas.org)

Purpose: To assess the potential of a new diagnostic technique called optical coherence tomography (OCT) for diagnosing and monitoring macular holes. (nyu.edu)

In PAT, tissue chromophores, such as oxygenated hemoglobin (HbO 2 ) and deoxygenated hemoglobin (Hb), absorb optical energy and emit acoustic waves that are detected by ultrasound transducers. (cdc.gov)

Electronically Controlled Coherent Optical Sampling For Optical Coherence Tomography , Optics Express, 2010, 18(10), pp. 9976-9990. (toptica.com)

The potential for improving the penetration depth of optical coherence tomography systems by using light sources with longer wavelengths has been known since the inception of the technique in the early 1990s. (nature.com)

The images produced by the mid-infrared system are compared with those delivered by a state-of-the-art ultra-high-resolution near-infrared optical coherence tomography system operating at 1.3 μm, and the potential applications and samples suited for this technology are discussed. (nature.com)
To identify and evaluate the use of contrast agents in optical coherence tomography (OCT) for ophthalmic applications. (arvojournals.org)

Current state-of-the-art commercially available OCT systems for NDT operate in the 1.3-μm wavelength range, utilizing the low water absorption and the maturity of optical fibers and components developed for telecommunications in this region. (nature.com)

Europe region captured the second largest market of optical coherence tomography in terms of revenue in 2016. (researchnester.com)

This approach to optical engines builds on over 10 years of Axsun's core integrated light source technology and is protected by a number of issued patents. (ptca.org)

Temporal and spatial coherence, two-beam and multiple-beam interference, interferometers. (mit.edu)

Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss. (listlabs.com)

Arrow indicates direction of the optical coherence tomography scan. (cdc.gov)
With a compact design, intuitive touch-screen interface, and nine IOL formulas, this A-scan provides advanced capabilities for identifying optical pathologies. (emseye.com)

Anatomy40

Diseases69

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment110

Psychiatry and Psychology4

Phenomena and Processes20

Disciplines and Occupations6

Technology, Industry, Agriculture3

Information Science10

Health Care18

Intravascular modalities for detection of vulnerable plaque: current status. (1/2999)

Choroidal neovascularization characteristics and its size in optical coherence tomography. (2/2999)

Optical imaging of the cervix. (3/2999)

Optical coherence tomography disc assessment in optic nerves with peripapillary atrophy. (4/2999)

Delayed regeneration of foveal cone photopigments in Vogt-Koyanagi-Harada disease at the convalescent stage. (5/2999)

Secondary retinal changes associated with choroidal naevi and melanomas documented by optical coherence tomography. (6/2999)

Onset of pulsatile pressure causes transiently increased filtration through artery wall. (7/2999)

Supplemental oxygen improves diabetic macular edema: a pilot study. (8/2999)

Tomography, Optical Coherence

Tomography, X-Ray Computed

Tomography

Macula Lutea

Diagnostic Techniques, Ophthalmological

Sense of Coherence

Nerve Fibers

Optic Disk

Visual Acuity

Fluorescein Angiography

Macular Edema

Retinal Ganglion Cells

Retina

Interferometry

Retinal Diseases

Optic Nerve Diseases

Fourier Analysis

Ophthalmoscopy

Optical Phenomena

Fovea Centralis

Imaging, Three-Dimensional

Anterior Eye Segment

Reproducibility of Results

Fundus Oculi

Glaucoma

Positron-Emission Tomography

Choroid

Retinal Perforations

Visual Field Tests

Gonioscopy

Epiretinal Membrane

Anatomy, Cross-Sectional

Equipment Design

Visual Fields

Retinal Photoreceptor Cell Outer Segment

Corneal Pachymetry

Retinal Pigment Epithelium

Retinal Photoreceptor Cell Inner Segment

Tomography, Emission-Computed

Tomography, Optical

Neointima

Microscopy, Acoustic

Image Enhancement

Ophthalmoscopes

Choroid Diseases

Macular Degeneration

Intraocular Pressure

Vitreous Detachment

Tomography, Spiral Computed

Optics and Photonics

Equipment Failure Analysis

Retinoscopes

Sensitivity and Specificity

Axial Length, Eye

Retinal Detachment

Subretinal Fluid

Myopia, Degenerative

Image Processing, Computer-Assisted

Refractometry

Diabetic Retinopathy

Retinoschisis

Electroretinography

Optic Disk Drusen

Photography

Anterior Chamber

Cornea

Glaucoma, Open-Angle

Algorithms

Retinal Drusen

Ultrasonography, Interventional

Choroidal Neovascularization

Prospective Studies

Vitrectomy

Multidetector Computed Tomography

Retinal Neurons

Endoscopes

Photoreceptor Cells, Vertebrate

Intravitreal Injections

Optical Fibers

Scleral Diseases