Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.
Infections caused by the HTLV or BLV deltaretroviruses. They include human T-cell leukemia-lymphoma (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED).
Antibodies reactive with various types of human T-cell leukemia/lymphoma antigens or bovine leukemia virus antigens.
Laboratory techniques that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.
Non-cadaveric providers of organs for transplant to related or non-related recipients.
The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.
Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.

Effect of MTHFR 677C>T on plasma total homocysteine levels in renal graft recipients. (1/3426)

BACKGROUND: Hyperhomocysteinemia is an established, independent risk factor for vascular disease morbidity and mortality. The 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism C677T has been shown to result in increased total homocysteine concentrations on the basis of low folate levels caused by a decreased enzyme activity. The effect of this polymorphism on total homocysteine and folate plasma levels in renal transplant patients is unknown. METHODS: We screened 636 kidney graft recipients for the presence of the MTHFR C677T gene polymorphism. The major determinants of total homocysteine and folate plasma concentrations of 63 patients, who were identified to be homozygous for this gene polymorphism compared with heterozygotes (N = 63), and patients with wild-type alleles (N = 63), who were matched for sex, age, glomerular filtration rate (GFR), and body mass index, were identified by analysis of covariance. The variables included sex, age, GFR, body mass index, time since transplantation, folate and vitamin B12 levels, the use of azathioprine, and the MTHFR genotype. To investigate the impact of the kidney donor MTHFR genotype on total homocysteine and folate plasma concentrations, a similar model was applied in 111 kidney graft recipients with stable graft function, in whom the kidney donor C677T MTHFR gene polymorphism was determined. RESULTS: The allele frequency of the C677T polymorphism in the MTHFR gene was 0.313 in the whole study population [wild-type (CC), 301; heterozygous (CT), 272; and homozygous mutant (TT), 63 patients, respectively] and showed no difference in the patient subgroups with various renal diseases. The MTHFR C677T gene polymorphism significantly influenced total homocysteine and folate plasma concentrations in renal transplant recipients (P = 0.0009 and P = 0.0002, respectively). Furthermore, a significant influence of the GFR (P = 0.0001), folate levels (P = 0.0001), age (P = 0.0001), body mass index (P = 0.0001), gender (P = 0.0005), and vitamin B12 levels (P = 0.004) on total homocysteine concentrations was observed. The donor MTHFR gene polymorphism had no influence on total homocysteine and folate levels. Geometric mean total homocysteine levels in patients homozygous for the mutant MTHFR allele were 18.6 micromol/liter compared with 14.6 micromol/liter and 14.9 micromol/liter in patients heterozygous for the MTHFR gene polymorphism and those with wild-type alleles (P < 0.05 for TT vs. CT and CC). Geometric mean folate levels were lower in CT and TT patients (11.2 and 10.2 nmol/liter) compared with CC patients (13.6 nmol/liter, P < 0.05 vs. CT and TT). CONCLUSIONS: This study demonstrates that homozygosity for the C677T polymorphism in the MTHFR gene significantly increases total homocysteine concentrations and lowers folate levels in kidney graft recipients, even in patients with excellent renal function (GFR more than median). These findings have important implications for risk evaluation and vitamin intervention therapy in these patients who carry an increased risk for the development of cardiovascular disease.  (+info)

A prospective, randomized trial of tacrolimus/prednisone versus tacrolimus/prednisone/mycophenolate mofetil in renal transplant recipients. (2/3426)

BACKGROUND: Between September 20, 1995 and September 20, 1997, 208 adult patients undergoing renal transplantation were randomized to receive tacrolimus/prednisone (n=106) or tacrolimus/prednisone/mycophenolate mofetil (n=102), with the goal of reducing the incidence of rejection. METHODS: The mean recipient age was 50.7+/-13.7 years. Sixty-three (30.3%) patients were 60 years of age or older at the time of transplantation. The mean donor age was 34.5+/-21.7 years. The mean cold ischemia time was 30.5+/-9.2 hr. The mean follow-up is 15+/-7 months. RESULTS: The overall 1-year actuarial patient survival was 94%; the overall 1-year actuarial graft survival was 87%. When the patient and graft survival data were stratified to recipients under the age of 60 who did not have delayed graft function, the overall 1-year actuarial patient survival was 97%, and the corresponding 1-year actuarial graft survival was 93%. There were no differences between the two groups. The overall incidence of rejection was 36%; in the double-therapy group, it was 44%, whereas in the triple therapy group, it was 27% (P=0.014). The mean serum creatinine was 1.6+/-0.8 mg/dl. A total of 36% of the successfully transplanted patients were taken off prednisone; 32% of the patients were taken off antihypertensive medications. The incidence of delayed graft function was 21%, the incidence of cytomegalovirus was 12.5%, and the initial and final incidences of posttransplant insulin-dependent diabetes mellitus were 7.0% and 2.9%; again, there was no difference between the two groups. CONCLUSIONS: This trial suggests that the combination of tacrolimus, steroids, and mycophenolate mofetil is associated with excellent patient and graft survival and a lower incidence of rejection than the combination of tacrolimus and steroids.  (+info)

Pediatric renal transplantation under tacrolimus-based immunosuppression. (3/3426)

BACKGROUND: Tacrolimus has been used as a primary immunosuppressive agent in adult and pediatric renal transplant recipients, with reasonable outcomes. Methods. Between December 14, 1989 and December 31, 1996, 82 pediatric renal transplantations alone were performed under tacrolimus-based immunosuppression without induction anti-lymphocyte antibody therapy. Patients undergoing concomitant or prior liver and/or intestinal transplantation were not included in the analysis. The mean recipient age was 10.6+/-5.2 years (range: 0.7-17.9). Eighteen (22%) cases were repeat transplantations, and 6 (7%) were in patients with panel-reactive antibody levels over 40%. Thirty-four (41%) cases were with living donors, and 48 (59%) were with cadaveric donors. The mean donor age was 27.3+/-14.6 years (range: 0.7-50), and the mean cold ischemia time in the cadaveric cases was 26.5+/-8.8 hr. The mean number of HLA matches and mismatches was 2.8+/-1.2 and 2.9+/-1.3; there were five (6%) O-Ag mismatches. The mean follow-up was 4.0+/-0.2 years. RESULTS: The 1- and 4-year actuarial patient survival was 99% and 94%. The 1- and 4-year actuarial graft survival was 98% and 84%. The mean serum creatinine was 1.1+/-0.5 mg/dl, and the corresponding calculated creatinine clearance was 88+/-25 ml/min/1.73 m2. A total of 66% of successfully transplanted patients were withdrawn from prednisone. In children who were withdrawn from steroids, the mean standard deviation height scores (Z-score) at the time of transplantation and at 1 and 4 years were -2.3+/-2.0, -1.7+/-1.0, and +0.36+/-1.5. Eighty-six percent of successfully transplanted patients were not taking anti-hypertensive medications. The incidence of acute rejection was 44%; between December 1989 and December 1993, it was 63%, and between January 1994 and December 1996, it was 23% (P=0.0003). The incidence of steroid-resistant rejection was 5%. The incidence of delayed graft function was 5%, and 2% of patients required dialysis within 1 week of transplantation. The incidence of cytomegalovirus was 13%; between December 1989 and December 1992, it was 17%, and between January 1993 and December 1996, it was 12%. The incidence of early Epstein-Barr virus-related posttransplant lymphoproliferative disorder (PTLD) was 9%; between December 1989 and December 1992, it was 17%, and between January 1993 and December 1996, it was 4%. All of the early PTLD cases were treated successfully with temporary cessation of immunosuppression and institution of antiviral therapy, without patient or graft loss. CONCLUSIONS: These data demonstrate the short- and medium-term efficacy of tacrolimus-based immunosuppression in pediatric renal transplant recipients, with reasonable patient and graft survival, routine achievement of steroid and anti-hypertensive medication withdrawal, gratifying increases in growth, and, with further experience, a decreasing incidence of both rejection and PTLD.  (+info)

Split liver transplantation. (4/3426)

OBJECTIVE: This study reviews the indications, technical aspects, and experience with ex vivo and in situ split liver transplantation. BACKGROUND: The shortage of cadaveric donor livers is the most significant factor inhibiting further application of liver transplantation for patients with end-stage liver disease. Pediatric recipients, although they represent only 15% to 20% of the liver transplant registrants, suffer the greatest from the scarcity of size-matched cadaveric organs. Split liver transplantation provides an ideal means to expand the donor pool for both children and adults. METHODS: This review describes the evolution of split liver transplantation from reduced liver transplantation and living-related liver transplantation. The two types of split liver transplantation, ex vivo and in situ, are compared and contrasted, including the technique, selection of patients for each procedure, and the most current results. RESULTS: Ex vivo splitting of the liver is performed on the bench after removal from the cadaver. It is usually divided into two grafts: segments 2 and 3 for children, and segments 4 to 8 for adults. Since 1990, 349 ex vivo grafts have been reported. Until recently, graft and patient survival rates have been lower and postoperative complication rates higher in ex vivo split grafts than in whole organ cadaveric transplantation. Further, the use of ex vivo split grafts has been relegated to the elective adult patient because of the high incidence of graft dysfunction (right graft) when placed in an emergent patient. Reasons for the poor function of ex vivo splits except in elective patients have focused on graft damage due to prolonged cold ischemia times and rewarming during the long benching procedure. In situ liver splitting is accomplished in a manner identical to the living donor procurement. This technique for liver splitting results in the same graft types as in the ex vivo technique. However, graft and patient survival rates reported for in situ split livers have exceeded 85% and 90%, respectively, with a lower incidence of postoperative complications, including biliary and reoperation for bleeding. These improved results have also been observed in the urgent patient. CONCLUSION: Splitting of the cadaveric liver expands the donor pool of organs and may eliminate the need for living-related donation for children. Recent experience with the ex vivo technique, if applied to elective patients, results in patient and graft survival rates comparable to whole-organ transplantation, although postoperative complication rates are higher. In situ splitting provides two grafts of optimal quality that can be applied to the entire spectrum of transplant recipients: it is the method of choice for expanding the cadaver liver donor pool.  (+info)

High-risk donors: expanding donor criteria. (5/3426)

Advances in the surgical techniques, preservation solutions, and methods for predicting eventual long-term renal function from expanded donors will be critical in allowing precise selection criteria for kidneys for transplantation, resulting in the optimum use of a scarce and precious resource. Until other options such as xenotransplantation or tissue engineering become realistic, the challenge for the millennium will be to identify which donor organs previously considered suboptimal can be safely used to expand the organ donor pool.  (+info)

Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation. (6/3426)

Dyskeratosis congenita is recognized by its dermal lesions and constitutional aplastic anemia in some cases. We report successful allogeneic bone marrow transplantation in two siblings with this disease from their sister, and their long term follow-up. We used reduced doses of cyclophosphamide and busulfan for conditioning instead of total body irradiation. Also, we report late adverse effects of transplantation which are not distinguishable from the natural course of disease.  (+info)

Relaxin secretion by human granulosa cell culture is predictive of in-vitro fertilization-embryo transfer success. (7/3426)

We have developed a cell culture system for human luteinizing granulosa cells which supports the timely and dynamic secretion of oestrogen, progesterone and relaxin in patterns that mimic serum concentrations of these hormones during the luteal phase of the menstrual cycle. There was a wide variation in the amount of relaxin secreted by the cultured cells for the 69 patients studied. As relaxin production was generally maximal by day 10 of culture, comparisons were made at this time point. It was observed that most of the conceptions occurred in patients with higher relaxin secretion in vitro. All cycles with relaxin > 800 pg/ml on day 10 had a term pregnancy while only 13% of cycles with relaxin < 200 pg/ml had term pregnancies. A limited number of cycles from donor/recipient cycles did not show similar results. Steroid concentrations were not predictive of conception. These results demonstrated that in-vitro production of relaxin is predictive of implantation success in in-vitro fertilization (IVF)-embryo transfer cycles. This supports the hypothesis that relaxin may be involved in implantation and that lowered relaxin concentrations may be a partial cause of poor pregnancy rates after IVF.  (+info)

Short-term toxicity in pediatric marrow transplantation using related and unrelated donors. (8/3426)

The use of volunteer, unrelated donors has substantially increased the number of potential donors for pediatric marrow transplantation during the past few years. We describe our single institution experience of short-term toxicity after pediatric marrow transplantation using sibling or unrelated donors. Fully matched (A, B and DR loci) donors were employed in 94% of the cases in both groups. Conditioning of similar intensity and uniform supportive care were employed in the two groups. Both primary non-engraftment and secondary graft failure were more common among recipients of unmanipulated URD grafts. Clinically significant (grades III-IV) acute GVHD and toxic mortality during the immediate post-transplant period were also higher in this group of patients. Pediatric marrow transplantation using volunteer, unrelated donors appears to be associated with an increased incidence of procedure-related toxic complications.  (+info)

The most common deltaretrovirus infection is HIV, which has become a major global health concern since its discovery in the early 1980s. HIV primarily infects CD4+ T cells, which are essential for cell-mediated immunity and immune responses. As HIV progressively destroys these cells, the body becomes less able to fight off infections and cancers.

Other deltaretrovirus infections include SIV, which affects nonhuman primates such as monkeys and chimpanzees, and FIV, which affects domestic cats. These viruses are similar to HIV in terms of their molecular structure and replication strategies but have some differences in their host range and disease progression.

Deltaretrovirus infections can be diagnosed through blood tests that detect the presence of viral antigens or genetic material. Treatment typically involves antiretroviral therapy (ART), which combines several drugs to suppress viral replication and slow disease progression. However, the virus can develop resistance to these drugs over time, making it essential to monitor treatment response and adjust medications as needed.

Prevention strategies for deltaretrovirus infections include safe sex practices such as using condoms, pre-exposure prophylaxis (PrEP) medication for high-risk individuals, and avoiding sharing needles or other injection equipment. Vaccines are also being developed to prevent HIV and other deltaretrovirus infections.

"Radical changes for organ donors". BBC News Online. 31 August 2006. "Transplant law 'likely to fail'". BBC News Online. 15 ... organs and tissue." The Act does not extend to Scotland; its counterpart there is the Human Tissue (Scotland) Act 2006. The Act ... The Human Tissue Act 2004 is an Act of the Parliament of the United Kingdom, that applied to England, Northern Ireland and ... The following orders have been made under this section: The Human Tissue Act 2004 (Commencement No. 1) Order 2005 (S.I. 2005/ ...
"Online Organ and Tissue Donor Registration". Service Ontario. Retrieved 18 July 2011. Be a Donor Donate Life America. "Local ... Donor Status: Yes, you are a registered organ and tissue donor. If one is not able to register online, you can either go to a ... "Online Organ and Tissue Donor Registration: Notice". Service Ontario. Retrieved 18 July 2011. Service Ontario. "Other ways to ... "Online Organ and Tissue Donor Registration". Services For Residents. Queen's Printer for Ontario. Retrieved 9 July 2011. ...
"Donate Life California , Organ and Tissue Donor Registry". Archived from the original on 2017-02-13. Retrieved 2017-01-19. " ... A decision to proceed was reached by the committee and the donor was a young girl from Utah who had been the victim of a car ... As of 2014, Craze was the only heart transplant recipient in the United States to survive 30 years with the same donor heart ...
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Schipper R, Schreuder G, D'Amaro J, Oudshoorn M (1996). "HLA gene and haplotype frequencies in Dutch blood donors". Tissue ... Rani R, Fernandez-Viña M, Stastny P (1998). "Associations between HLA class II alleles in a North Indian population". Tissue ... Sirén M, Sareneva H, Lokki M, Koskimies S (1996). "Unique HLA antigen frequencies in the Finnish population". Tissue Antigens. ... Klemola T, Savilahti E, Koskimies S, Pelkonen P (1988). "HLA antigens in IgA deficient paediatric patients". Tissue Antigens. ...
Schipper RF, Schreuder GM, D'Amaro J, Oudshoorn M (Nov 1996). "HLA gene and haplotype frequencies in Dutch blood donors". ... Tissue Antigens. 11 (2): 96-112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067. "HLA Nomenclature @ hla.alleles.org". ... Tissue Antigens. 48 (5): 562-74. doi:10.1111/j.1399-0039.1996.tb02670.x. PMID 8988539. (HLA-A alleles). ... Tissue Antigens. 61 (5): 403-407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. Sasazuki, Takehiko; Tsuji, Kimiyoshi; ...
"GROW HUMAN TISSUE OUTSIDE THE BODY; Two Lying-In Hospital Physicians Succeed Where Others Had Failed". The New York Times. June ... "Actress Critically Ill; Appeal for Blood Donors Made in Behalf of Mary Martin". The New York Times. May 30, 1945. " ...
The project has collected a variety of tissue samples (> 50 different tissues) from more than 700 post-mortem donors. This has ... GTEx has helped understand the tissue-sharing and tissue-specificity of eQTLs. The genomic resource was developed to "enrich ... "Genetic effects on gene expression across human tissues" (PDF). Nature. 550 (7675): 204-213. Bibcode:2017Natur.550..204A. doi: ... genetics project aimed at understanding the role of genetic variation in shaping variation in the transcriptome across tissues ...
Effects of donor's age, tissue, and genotype". Laboratory Investigation. 23 (1): 86-92. PMID 5431223. Salk, D; Au, K; Hoehn, H ... They affect only one tissue and can be classified as unimodal progeroid syndromes. Segmental progeria, which is more frequently ... Chan, Amanda L. (13 September 2012). "Lizzie Velasquez, Born Without Adipose Tissue: 'Maybe You Should Stop Staring And Start ... Misrepair-accumulation aging theory suggests that the abnormality of tissue structure is the common point between premature ...
Effects of donor's age, tissue, and genotype". Lab. Invest. 23 (1): 86-92. PMID 5431223. Salk D, Au K, Hoehn H, Martin GM (1981 ... Soft-tissue sarcomas are the most common cancer types. Other types of skin cancer, other epithelial cancers such as thyroid and ... This is due to atrophy of the subcutaneous tissue and dermal fibrosis. Over time, the characteristic facial features may be ... In addition, it decreases activity of genes activated in human Werner syndrome and increases gene activity involved in tissue ...
You can still be a tissue donor. Greer, David M. (30 December 2021). "Determination of Brain Death". New England Journal of ... The OPO searches to see if the deceased is registered as a donor, which serves as legal consent; if the deceased has not ... When mechanical ventilation is used to support the body of a brain dead organ donor pending a transplant into an organ ... "National Donate Life America Donor Designation State Report Card 2013" (PDF). pp. 6 & 7. Archived from the original (PDF) on ...
Mismatched donor and recipient tissues can lead to rejection of the tissues. There are multiple methods of tissue typing. ... Tissue typing is a procedure in which the tissues of a prospective donor and recipient are tested for compatibility prior to ... When donor and recipient HLA are matched, donor tissues are significantly more likely to be accepted by the recipient's immune ... an immune response against the donor tissues can be triggered. More specifically, HLA mismatches between organ donors and ...
The tissues and organs that are able to be donated by a living donor are: Bone marrow Kidney Part of the liver Lung (this ... Australian donor rates are on the rise. Between 2009 and 2013, donor numbers increased by 29%. In 2009 there were 11.4 donors ... Deceased donors have been declared dead and are maintained in ICU on ventilators so tissue oxygenation continues until the ... "Organ and tissue donation by living donors, guidelines for ethical practice for health professionals (2007)". Australian ...
It contains mesenchymal stem cells from fat tissue of adult donors. It was approved for use in the European Union in March 2018 ... Darvadstrocel works by reducing inflammation and facilitating the growth of tissue in the fistula tract. The ADMIRE-CD trial ...
Transplantation: pairing of donor and recipient. Science 168; 1170. 8. Olerup, O and H. Zetterquist. 1992. HLA-DR typing by PCR ... Tissue Antigens 84:439 (Wikipedia articles that are too technical from April 2016, All articles that are too technical, All ... Tissue Antigens. 39:225. 9. Lindemann M. 2014. Ex vivo assessment of cellular immune function - applications in patient care ... The MLR was first recognized when researchers mixed leukocytes from two unrelated donors in culture. After several days, ...
Tissue Transplantation & Therapy: 5-10. doi:10.4137/CTTT.S25959. Pillai, Vinod G.; Chen, Chao-Long (April 2016). "Living donor ... This was followed by Taiwan's first dual-graft living donor liver transplantation in 2002. This body of work led to ... The next year, Chen oversaw Taiwan's first living donor liver transplantation. In 1997, Chen performed Asia's first split-liver ... Palaniappan, Nagarajan; Chen, Chao-Long (August 2016). "Living Donor Liver Transplantation: Cumulative Insights from Taiwan". ...
... the donor, and implanted in the recipient. Xenografts involve taking donor tissue from another species. Allografts and ... When appropriate, a nearby donor may be used to supply innervation to lesioned nerves. Trauma to the donor can be minimized by ... Phillips, J.B., et al., Neural Tissue Engineering: A self-organizing collagen guidance conduit. Tissue Engineering, 2005. 11(9/ ... The nerve repair must be covered by healthy tissue, which can be as simple as closing the skin or it can require moving skin or ...
Ovarian tissue banking - Ovarian tissue is frozen after oophorectomy. Even after long-term androgen therapy, ovaries usually ... The sperm donor must be chosen before oophorectomy. Allows the possibility for embryos to later be placed in a surrogate, as ... Although many AAS are not potentiated in androgenic tissues, they have similar effects to testosterone in other tissues like ... but may eventually be possible in a lab as techniques for tissue culture improve. This option does not usually allow for ...
Alt URL Office of the Press Secretary (Apr 9, 2001). "National Organ and Tissue Donor Awareness Week, 2001". Federal Register. ... Alt URL Office of the Press Secretary (Apr 24, 2002). "National Organ and Tissue Donor Awareness Week, 2002". Federal Register ...
In Europe, the screening procedures are regulated by the EU Tissue Directive. The CDC standards for sperm donor screening ... often limiting sperm donors to the ages of 21-39 (see paternal age effect), and genetic and health screening of donors. In ... and positive donors may still donate at sperm banks. Donor screening for cytomegalovirus (CMV) is carried out by testing for ... and hemoglobin evaluations are performed on the majority of sperm donor applicants in the United States. Donors of Jewish, ...
... deceased donor transplantation was not performed. The kidney was the easiest organ to transplant: tissue typing was simple; the ... Deceased donors can be divided in two groups: Brain-dead (BD) donors Donation after Cardiac Death (DCD) donors Although brain- ... Deceased donor kidneys with higher kidney donor profile index (KDPI) scores (a score used to determine suitability of donor ... or living-donor transplantation depending on the source of the donor organ. Living-donor kidney transplants are further ...
It is stored and released from adipose tissue, so its effects can continue long after dosage stops. It is detectable in the ... ISBN 978-3-85200-181-4. Drugs.com archive for etretinate "Donor Selection Guidelines: Etretinate". UK Blood Transfusion and ... Tissue Transplantation Services. "Medications taken on a regular basis that exclude you from donating blood". Héma-Québec. " ...
... tissue could ease donor shortage". NBC News. Retrieved May 1, 2020. "Organ Donation Statistics , Organ Donor". www.organdonor. ... Salzman, Sony (September 23, 2019). "3D-printed hears with 'beating' tissue could ease donor shortage". NBC News. Retrieved 1 ... "Matching Donors and Recipients , Organ Donor". www.organdonor.gov. 2018-05-07. Retrieved 2020-04-02. Afsana; Jain, Vineet; Jain ... the proximity of the patient to the donor, and the viability time of the donor organ. In the United States, 20 people die ...
Folds in the donor tissue may reduce the quality of vision, requiring repair. Rejection of the donor tissue may require ... During surgery the patient's corneal endothelium is removed and replaced with donor tissue. With DSEK, the donor includes a ... To improve visual acuity by replacing the opaque or distorted host tissue by clear healthy donor tissue. The most common ... The donor tissue is then sewn in place with sutures. Antibiotic eyedrops are placed, the eye is patched, and the patient is ...
Hensch, Mark (June 2, 2017). "Warren: Trump's Paris deal exit a 'big gift to Republican donors'". The Hill. "Massachusetts ... Research, Center for Biologics Evaluation and (December 4, 2020). "Tissue Guidances". FDA. Archived from the original on March ... "Senate Dems to FDA: Finish lifting gay blood donor ban". The Hill. July 14, 2015. "Historic, Comprehensive LGBT Non- ... "a big gift to Republican donors" rather than about "jobs versus the environment". She furthered, "In this democracy, government ...
Fetal tissue restores lost sight MedicalNewsToday. 28 October 2004 "Stem cells used to restore vision". 28 April 2005 - via ... "First donor iPSC-derived RPE cell transplantation in AMD patient". RIKEN Center for Developmental Biology. 4 April 2017. ... Time and cost used in the surgery has been significantly reduced by using super donor cells, cells derived from people with ... Then in March 2017 team carried out the world's first successful transplant of retinal cells created from donor iPS cells into ...
Furthermore, it is possible to transplant freeze-dried donor tissue. The freeze-drying process ensures this tissue is dead, so ... so the donor tissue is not required to be blood type matched. Eye banks check the donor corneas for any disease or cellular ... The corneal transplant surgeon trephines a lenticule of corneal tissue and then grafts the donor cornea to the existing eye ... Complications of corneal transplants are mostly related to vascularization of the corneal tissue and rejection of the donor ...
The removed part of donor cornea is known as corneal button. The donor tissue is then sutured to the patient eye. Dense corneal ... In this technique, the opaque part of the cornea is removed and replaced with donor tissue, leaving healthy part of the cornea ... In this, the opaque cornea is replaced with donor tissue. Depending on type and density of corneal opacity different types of ... In this procedure, the anterior layers of cornea are removed and replaced with donor tissue, leaving the endothelial layer and ...
"Inova Blood Donor Services Joins Nation's First Emergency Blood Reserve". Inova Newsroom. 2022-04-25. Retrieved 2022-05-16. ... Burrell, Morgan (2021-09-11). "South Texas Blood and Tissue Center joins first-of-its-kind emergency blood reserve". WOAI. ... Tissue Center (San Antonio, Texas) Stanford Blood Center (Palo Alto, California) SunCoast Blood Centers (Sarasota, Florida) The ... Inova Blood Donor Services (Sterling, Virginia) LIFELINE Blood Services (Jackson, Tennessee) LifeServe Blood Center (Des Moines ...
... and the donor must retain access to it for buoyancy control, so donation of the primary regulator to help another diver is ... and inject gas into the tissues, along with possible contaminants. Scuba is safety-critical equipment, as some modes of failure ... and this in turn reduces air consumption during the rescue and frees the donor's hand.[citation needed] Some diver training ...
... and as a result many accused him of receiving preferential treatment with respect to donor waiting lists. Before undergoing the ... an inherited condition characterized by the deposition of insoluble proteins in organs and tissues. Though rare, the disease ... license identification of potential donors, and establishing an organ donation trust fund from voluntary donations to promote ... supported legislation that encouraged organ transplants by guaranteeing access to the families of potential organ donors by ...
Other than fat, glucose is stored in most tissues, as an energy resource available within the tissue through glycogenesis which ... One important reaction that uses these activated isoprene donors is sterol biosynthesis. Here, the isoprene units are joined to ... A parallel approach is to identify the small molecules in a cell or tissue; the complete set of these molecules is called the ... Ions are also critical for nerve and muscle function, as action potentials in these tissues are produced by the exchange of ...
"Detritus can be broadly defined as any form of non-living organic matter, including different types of plant tissue (e.g. leaf ... and mineral electron donors in hydrothermal vents and hot springs. These trophic levels are not binary, but form a gradient ... Many of the Earth's elements and minerals (or mineral nutrients) are contained within the tissues and diets of organisms. Hence ... Plantago genera have been found to produce defensive compounds called iridoid glycosides that are sequestered in the tissues of ...
In normal lymphoid tissue, recirculating resting B cells migrate through the FDC networks, whereas antigen-activated B cells ... in which case both donors' and recipients' FDCs networks may later be found in recipients' lymphoid compartments. Interaction ... These sarcomas often involve lymphoid tissues, but in a number of cases the tumor has been found in the liver, bile duct, ... Factor Mfge produced in lymphoid tissues mainly by FDCs is known to enhance engulfment of apoptotic cells. Deficit of this ...
... "donor") and uninfected ("target") cell to allow cell-to-cell transmission. As viral synapses allow the virus to spread directly ... residing in lymphoid tissues that mediate cell-to-cell spread of the virus via virological synapses. These findings highlight a ... "Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells". Cell Rep. ...
Among the 12 tissues examined the highest level of expression was observed in heart, followed by brain and steroidogenic tissue ... In the spindle transfer procedure, the nucleus of an egg is inserted into the cytoplasm of an egg from a donor female which has ... Measurement of the levels of the mtDNA-encoded RNAs in bovine tissues has shown that there are major differences in the ... but their tissues do not produce more ROS as predicted by the 'Vicious Cycle' hypothesis. Supporting a link between longevity ...
A body broker (also non-transplant tissue banks) is a firm or an individual that buys and sells cadavers or human body parts. ... In some cases, this is done illegally against the donor's wishes or by employees who act independently of the institution. In ... A Reuters journalist bought human body parts, then learned a donor's heart-wrenching story, Reuters, Brian Grow and John ...
Physiology is the study of life, specifically, how cells, tissues, and organisms function. She is a scientist who did her ... simple&donor_search=Sports NC State University Computer Science Hall of Fame: William G. Pagán Taking Flight: Meet William ... Alcalá developed laboratory methods to study the histology of ocular tissue, which ultimately helped to explain the development ...
Post-operative complications can be divided into donor-site and recipient-site problems. Donor-site complications include wound ... If only skin is missing and underlying galea, muscle or connective tissue are intact, a skin graft can be used. A skin graft ... The large blood vessels and nerves of the scalp don't pierce this layer.Loose connective tissue between the periosteum and the ... Thus, if vascular and nervous anatomy is respected, the skin, subcutaneous tissue and galea aponeurotica can be lifted off the ...
The donor for both transplants was Ahmet Kaya, who, hit by a train in Uşak, died on January 20 at the age of 39. Ömer Özcan ... His scientific field covers aesthetic surgery for face and body, breast reconstruction, tissue engineering, facial muscles ... The donor was Tevfik Yılmaz, a 19-year young man from Uşak, who had attempted suicide on May 8. He was declared brain death in ... This is a first-ever operation in the world because former transplants were carried out by using organs from living donors. It ...
Several cell types or tissues, e.g. osteoblasts, chondrocytes, cardiac tissue, gastrointestinal smooth muscle cells, and ... 2005). "Changes in serum LECT 2 levels during the early period of liver regeneration after adult living related donor liver ... which leads to its tissue deposition. However, there appears to be clear genetic variations that lead LECT2 tissue deposition. ... mRNA for LECT2 is highly expressed in liver tissue and expressed at far lower levels in a wide range of other tssues. Human ...
"Hemochromatosis Donor Program". "Welcome". Hemochromatosis.org - An Education Website for Hemochromatosis and Too Much Iron. ... Hemosiderosis is iron overload that does not cause tissue damage, while hemochromatosis does. Hemosiderosis is arbitrarily ... by German pathologist Friedrich Daniel von Recklinghausen in 1889 when he described an accumulation of iron in body tissues. ... is characterized by an accelerated rate of intestinal iron absorption and progressive iron deposition in various tissues. This ...
... but highly effective O2 donors in terms of tissue oxygenation. Additional effects include increases in blood serum iron, ... Nearly 50% of autologous donations are not used by the donor and are discarded, as current standards do not allow transfusion ... In addition, as gases are in the dissolved state within PFCs, it pO2 promotes efficient oxygen delivery to peripheral tissues. ... The test utilizes 12 antisera directed against the blood group antigens, obtained from donor plasma. The antigens are labeled ...
Extensive specimen material and artifacts were given to the museum by collectors and donors, such as the Boone collection of ... Concordant with research developments, new collection types, such as frozen tissue collections, requiring new collecting and ...
STAP cells can form placental tissue meant they could have made cloning considerably easier by bypassing the need for a donor ... STAP cells injected into mouse embryos grew into a variety of tissues and organs found throughout the body. According to the ... Center for Tissue Engineering & Regenerative Medicine. Press Release (March 14, 2014). "Interim report on the investigation of ... And adapted to human tissue, the technique could have led to cheap and simple procedures to create patient-specific stem cells ...
Murray stated that he suffered from idiopathic pulmonary fibrosis, a scarring of the lung tissue leading to shortness of breath ... Murray and his corporation were a major donor to Romney and other Republicans, and employees reported frequent instances of ...
... donors and external funding sources including the Canadian Institutes of Health Research, Canadian Cancer Society, Terry Fox ... stem cell biology and tissue regeneration, mouse models of human disease, genomic medicine and systems biology. The institute ...
... "screen and test donors for relevant communicable disease agents and diseases and to ensure that HCT/Ps (Human Cells, Tissues, ... Biomedical Tissue Services (BTS) was a Fort Lee, New Jersey, human tissue recovery firm that was shut down by the U.S. Food and ... such as allowing cadavers to deteriorate before collecting tissue and parts, not testing donor material for diseases such as ... which is a typical industry practice for cosmetic reconstruction of tissue donors.[citation needed] According to government ...
... which breaks down the connective tissue fiber elastin. Besides limiting elastase activity to limit tissue degradation, A1PI ... Alpha-1 antitrypsin concentrates are prepared from the blood plasma of blood donors. The US Food and Drug Administration (FDA) ... Besides liver cells, A1PI is produced in bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth ... This suggests a role for α1PI not only in locomotion of lymphocytes through tissue, but as a consequence of infection, a ...
In both types of histone methyltransferases, S-Adenosyl methionine (SAM) serves as a cofactor and methyl donor group. The ... carcinogenesis of the tissue, and tumorigenesis. Histone-Modifying Enzymes Histone acetyltransferase (HAT) Histone deacetylase ...
Sirkin, M; Sanders, R; Dipasquale, T; Herscovici Jr, D (1999). "A staged protocol for soft tissue management in the treatment ... Younger, EM; Chapman, MW (1989). "Morbidity at bone graft donor sites". Journal of Orthopaedic Trauma. 3 (3): 192-5. doi: ... Sirkin, M; Sanders, R; Dipasquale, T; Herscovici Jr, D (1999). "A staged protocol for soft tissue management in the treatment ... Topical coverage includes hard and soft tissue trauma, pertaining to the following types of injuries: ligament, bone, muscle, ...
It also forms stronger complexes with oxygen-donor ligands than with nitrogen-donor ligands. deferoxamine, a naturally ... was developed as an H2 antagonist by chemically engineering the molecule for maximum specificity to an isolated tissue ... O or F as with ligands whose donor atoms are P, S or Cl. Penicillamine, which contains nitrogen and sulphur donor atoms, is ... This means that it forms roughly equally strong complexes with ligands whose donor atoms are N, ...
The department conducted the first liver transplant in 2001-a deceased donor liver transplant. Along with Dr. S. Nundy, he ... radiofrequency ablation and percutaneous alcohol injection into tumor tissue. The unit has treated patients from all over India ... Gupta, S; Singhal, A; Goyal, N; Vij, V; Wadhawan, M (Apr 2011). "Portal biliopathy treated with living-donor liver transplant: ... Singhal, A; Srivastava, A; Goyal, N; Vij, V; Wadhawan, M; Bera, M; Gupta, S (Dec 2009). "Successful living donor liver ...
Organ donors can be living or dead. The type of organ donations are as follows: Living donors are permitted to donate the ... Organs and tissues from a person declared legally dead can be donated after consent from the family has been obtained. ... In 2019, Tamil Nadu recorded only 128 donors. By 2019, the state had transplanted 7,783 organs from deceased donors. Numerous ... The deceased donor program functions under the banner of Jeevandan since January 2013 in the state. The deceased organ donation ...
... is composed of human allogeneic (donor-derived) thymus tissue that is processed and cultured ... Allogeneic processed thymus tissue is the first thymus tissue product approved by the U.S. Food and Drug Administration (FDA). ... Allogeneic processed thymus tissue, sold under the brand name Rethymic, is a thymus tissue medical therapy used for the ... "Enzyvant Receives FDA Approval for Rethymic (allogeneic processed thymus tissue-agdc), a One-Time Regenerative Tissue-Based ...
... especially with the current lack in transplantable tissue. In addition, questions have been raised about tissue collected from ... Nevertheless, cost and donor scarcity have prompted researchers to look for new supportive treatments that can act as "bridge" ... Primary human hepatocytes sourced from donor organs are the most suitable for use but present several problems in their cost ... American Society for Artificial Internal Organs Tissue engineering Pless, G. (2007). "Artificial and bioartificial liver ...
All luciferases are classified as oxidoreductases (EC 1.13.12.-), meaning they act on single donors with incorporation of ... intracellular pH and transparency of overlying tissue, in addition to the amount of luciferase. Luciferase is a heat-sensitive ...
Rosentreter A, Schild AM, Dinslage S, Dietlein TS (February 2012). "Biodegradable implant for tissue repair after glaucoma ... or later on create a necessity for revision surgery with the sole or combinative use of donor patch grafts or collagen matrix ...
Organ or tissue procurement organizations should report this information to the donors physician when the donor is deceased. ... Organ or tissue procurement organizations should report this information to the donors physician when the donor is deceased. ... or have received untested tissue or tissue from an HBsAg-positive donor, and prophylaxis with hepatitis B immune globulin and ... provider that they will or have received untested tissue or tissue from an anti-HCV repeatedly reactive donor. ...
... to make the recipient non-responsive to the donor. Information from these studies could lead to the use of donor tissue to ... Information from these studies could lead to the use of donor tissue to manipulate the recipients immune system in a ... Full Text AI-94-012 AFFECTING GRAFT SURVIVAL WITH DONOR IMMUNE TISSUE NIH GUIDE, Volume 23, Number 6, February 11, 1994 RFA: AI ... This Request for Applications (RFA), Affecting Graft Survival With Donor Immune Tissue, is related to the priority areas of ...
Tissues, and Semen for Antibody to Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus ... Epidemiologic Notes and Reports Testing Donors of Organs, ... Thus, organs, tissues, and semen obtained from HTLV-III/LAV ... Epidemiologic Notes and Reports Testing Donors of Organs, Tissues, and Semen for Antibody to Human T-Lymphotropic Virus Type ... It is additionally recommended that blood or serum from donors of organs, tissues, or semen intended for human use be similarly ...
... our intent was not to propel readers to toss out their donor cards. ... When ICIJ began discussing how to write a story about the untraceable and opaque trade in human tissues, ... Tissue banks overseas have allegedly taken tissue without consent.. And the tissue banking industry largely reacts to our ... Some states allow donors to specify whether their tissue can go to a for-profit company, be used for cosmetic purposes or be ...
... and scientific considerations for tissue donors. The daylong workshop was held 9 July 2010 at the Ritz-Carlton Hot … ... from a public workshop sponsored by the American Association of Tissue Banks (AATB) held to discuss West Nile Virus (WNV) ... West Nile Virus workshop: scientific considerations for tissue donors Scott A Brubaker et al. Cell Tissue Bank. 2012 Aug. ... West Nile Virus workshop: scientific considerations for tissue donors Scott A Brubaker 1 , P Robert Rigney ...
West Nile Virus RNA in Tissues from Donor Associated with Transmission to Organ Transplant Recipients Dianna M. Blau. , Ingrid ... WNV in tissues from solid organ donor associated with WNV transmission to solid organ transplant recipients* ... West Nile Virus RNA in Tissues from Donor Associated with Transmission to Organ Transplant Recipients. ...
hgFixed.gtexSampleV8 contains metadata about sample time, collection site, and tissue, connected to the donor field in the ... Images from stained tissue samples can be viewed via the NCI histopathology viewer. The Qiagen PAXgene non-formalin tissue ... Gene Expression in 54 tissues from GTEx RNA-seq of 17382 samples, 948 donors (V8, Aug 2019) (POMC) ... The bargraph display has the same width and tissue order for all genes. Mouse hover over a bar will show the tissue and median ...
... tissues, and semen for antibody to human T-lymphotropic virus type III/lymphadenopathy-associated virus ... Testing donors of organs, tissues, and semen for antibody to human T-lymphotropic virus type III/lymphadenopathy-associated ... Testing donors of organs, tissues, and semen for antibody to human T-lymphotropic virus type III/lymphadenopathy-associated ... Transmission of human T-cell lymphotropic virus type III (HTLV-III) by artificial insemination by donor. Stewart GJ, Tyler JP, ...
... eye and tissue donors, and to discuss that decision with their families. For more information on organ, eye and tissue donation ... eye and tissue donors to remain on the donor registry, without the hassle of renewing that choice repeatedly throughout their ... Home // Donation Essentials Blog // Colorado Moves to Yes-Carryover Process for Organ, Eye and Tissue Donor Registry ... Colorado is adopting the yes-carryover process for the states organ, eye and tissue donor registry with changes to the process ...
Register your decision for organ and/or tissue donation - you need your Saskatchewan Health Services Card number, first and ... Saskatchewan Organ and Tissue Donor Registry. How to register. Registering your decision for organ and/or tissue donation is ...
... eye and tissue donor in Colorado. Congratulations on making the important decision to save lives. ... Register as an organ, eye and tissue donor. Registering as an organ, eye and tissue donor means you have made the decision to ... When you register as an organ, eye and tissue donor, your registration remains in effect unless you change it. If you do not ... YES, IM ALREADY A DONOR. If you are not already a donor, please fill out the fields below. Fields marked with an * are ...
Children as potential deceased organ and tissue donors. Research output: Chapter in Book/Report/Conference proceeding › Book ...
Tissue and Organ Procurement 9. For a better life Publication: [England] : HMSO, [19--] Subject(s): Tissue Donors. Tissue and ... Start Over You searched for: Subjects Tissue Donors ✖Remove constraint Subjects: Tissue Donors ... Tissue Donors 8. Give love, give life: be an organ donor! Publication: Cedar Grove, N.J. : American Liver Foundation, [19--] ... Tissue Donors 4. Schön, wenn Sie Ihr Herz verschenkt haben: wollen Sies nach Ihrem Tod noch einmal tun? ...
The staggered approach allowed the hepatic tissue time to adjust and the solution was able to spread throughout the organ more ... Since human cells are especially sensitive, donor livers are stored above freezing at 4 degrees Celsius. As a result, doctors ... The machine profusion process helps supercool the liver without freezing the tissue. Credit: Massachusetts General Hospital. ... tissue can be stored at subzero temperatures without damage. They were able to do this by adding a modified glucose compound, 3 ...
Organ and tissue transplantation in the European union : management of difficulties and health risks linked to donors / edited ... Human tissue : ethical and legal issues. by Nuffield Council on Bioethics.. Material type: Text; Format: print Publication ... Transplanting human tissue : ethics, policy, and practice / edited by Stuart J. Youngner, Martha W. Anderson, Renie Schapiro. ... of Essential Health Technologies , WHO Consultation on the Ethics, Access and Safety in Tissue and Organ Transplantation : ...
Donors can make an appointment with South Texas Blood & Tissue by calling 210-731-5590 or visiting SouthTexasBlood.org. Same- ... biobridge global, Blood Donation, blood donors, Blood Drive, blood shortage, cancer, donor home, hemorrhage, Home, image-center ... Tissue. "Every blood transfusion that is given to a patient in need comes from a volunteer donor, and we are calling on our ... day appointments and walk-ins are available at the centers eight donor rooms, as well as at community blood drives. Donors at ...
... in both donors. The causes of donor death were trauma in 51 donors, suicide in 33, cardiac arrest in 7, electric shock in 5, ... The donors clinical history and cause of death were assessed for secondary analysis. RESULTS:. Of 200 ocular tissues (100 ... Clinical Utility of COVID-19 Real Time-Polymerase Chain Reaction Testing of Ocular Tissues of Non-COVID-19 Cornea Donors Deemed ... reaction in corneal rims and conjunctival tissues from 100 donors who were found suitable for transplantation as per the donor ...
Allograft (Donor Tissue) Studies have suggested that allograft (donor tissue from a cadaver) has higher failure rates in ... The most common options include patellar tendon, hamstring tendon, and donor tissue (allograft). Each of these choices has ... A graft is tissue that is moved from one location to another. When the source of the graft is from the individual having ... The ACL graft is the type of tissue used to create the new ACL ligament. ACL reconstruction can be done with several different ...
Each organ or tissue donor can save many lives, and becoming one is simple: join your States donor registry, indicate your ... April is National Organ and Tissue Donor Awareness Month.. National Donate Life Month (NDLM) was instituted by Donate Life ... eye and tissue donors and to celebrate those that have saved lives through the gift of donation.. Here is the presidential ... tissue, blood, and stem cell donors throughout our Nation. ... April: National Organ and Tissue Donor Awareness Month * Get ...
In Australia, skin can only be donated from deceased donors.. You can register your wish to be a tissue donor in Australia on ... There are many reasons to become a tissue donor. Find out more... ... Tissue donation can enhance and even save peoples lives. Find ... Find out how you can register your wish to be considered for tissue donation... ...
... J Heart Lung Transplant. 2003 Nov;22(11):1183-200. doi: 10.1016/s1053- ... Tissue Donors* * Tissue and Organ Procurement / standards* ...
Tissue and organ procurement. Tissue donors. WO 664. Cell- and tissue-based therapy (works on stem cell transplantation classed ... WD 300-380 Connective Tissue Diseases (Note: Several numbers in the WD 300-330 Immune System Related Diseases area had already ... been cancelled with 2019 summer edition.) Connective Tissue Diseases and Collagen Diseases moved to new section: QZ 192-196. ...
... grateful for one donor among the more than 11.8 million enrolled in the states Joshua Abbott Organ and Tissue Donor Registry. ...
... eye and tissue donation, celebrated on February 14th. ... National Donor Day is an observance day dedicated to spreading ... Tissue Donation*Birth Tissue Donation*Donor Registries *National Donate Life Registry*National Donate Life Living Donor ... eye and tissue donor or contributing to the DLA cause, you can also download our National Donor Day graphics, Donor Day Flyer ... Transplants rely on the generosity of organ, eye and tissue donors, and there are not enough donors to meet the need. ...
HHS Tissue and Organ Donor Epidemiology Study (TODES) Working Group. Description of Collaborative Activity:. This Working Group ... supports the design and conduct of HHS Tissue and Organ Donor Epidemiology Study (TODES).. ...
... ... Additionally, a big thank you to the local businesses who generously donated gifts that were given to the donors as a token of ... The Shavano Park Women hosted a Blood Drive with the South Texas Blood and Tissue Center (STBTC) on April 30, 2022, at Shavano ... Many thanks to the donors for giving the "Gift of Life" that will benefit many patients. Shavano Park is helping meet the ...
... a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, according to the ... "The Cornea Donor Study demonstrates the viability of older donor tissue in the majority of cases with endothelial disease. In ... who routinely get corneas from young donors. But young donor corneas are relatively rare. In 2012, corneal donors under age 31 ... It involves removing a portion of the damaged cornea and grafting corneal tissue from a deceased donor in its place. More than ...
  • These studies have the potential to help develop protocols for enhancing solid organ graft survival by infusion of donor cells prior to or after transplantation. (nih.gov)
  • Donor specific transplant tolerance has been achieved for solid organ transplantation in animal models via induction regimens using donor immunocompetent tissue, e.g., bone marrow and peripheral blood. (nih.gov)
  • I can specify if there are tissues I do not what to donate, or if I object to my tissue being used either for research or transplantation. (icij.org)
  • The goal is to determine how to fill gaps in knowledge of WNV and tissue donation and transplantation by pursuing relevant scientific studies. (nih.gov)
  • Workshop participants included subject-matter experts from the U.S. Food and Drug Administration, the Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Health Canada, the Public Health Agency of Canada, AATB-accredited tissue banks including reproductive tissue banks, accredited eye banks of the Eye Bank Association of America, testing laboratories, and infectious disease and organ transplantation professionals. (nih.gov)
  • Delivering viable organs to matching recipients within the window of viability can often be the most challenging aspect of organ transplantation," said Seila Selimovic, Ph.D., director of NIBIB's Engineered Tissues program. (nih.gov)
  • Organ and tissue transplantation in the European union : management of difficulties and health risks linked to donors / edited by Yvon Englert. (who.int)
  • Ethics, access and safety in tissue and organ transplantation : issues of global concern, Madrid, Spain, 6-9 October 2003 : report. (who.int)
  • Clinical Utility of COVID-19 Real Time-Polymerase Chain Reaction Testing of Ocular Tissues of Non-COVID-19 Cornea Donors Deemed Suitable for Corneal Retrieval and Transplantation. (bvsalud.org)
  • The expression of SARS-CoV-2 RNA was assessed by reverse transcription - polymerase chain reaction in corneal rims and conjunctival tissues from 100 donors who were found suitable for transplantation as per the donor screening guidelines of the Global Alliance of Eye Bank Associations . (bvsalud.org)
  • The overall prevalence of SARS-CoV-2 was 1% (2% for conjunctival and 0% for corneal samples, P value = 0.5) in the donors who were found suitable for cornea recovery and transplantation . (bvsalud.org)
  • The findings of exceptionally low positive rates in our samples validate the criticality of history -based donor screening and do not support the necessity of postmortem PCR testing as a criterion for procurement and subsequent use for corneal transplantation . (bvsalud.org)
  • Organ donation takes healthy organs and tissues from one person for transplantation into another. (medlineplus.gov)
  • Organ Procurement Organizations (OPOs) are nonprofit organizations responsible for recovering organs from donors for transplantation in the United States. (nih.gov)
  • Traumatic scars (i.e. from an accident) can be treated with follicular unit hair transplantation as the hair grows quite well in scar tissue, as long as the scar is not thickened (hypertrophic). (bernsteinmedical.com)
  • Organ donation and transplantation is removing an organ from one person (the donor) and surgically placing it in another (the recipient) whose organ has failed. (clevelandclinic.org)
  • In addition to allogeneic HCT, procedures associated with high risk of GVHD include transplantation of solid organs containing lymphoid tissue and transfusion of unirradiated blood products. (medscape.com)
  • n 2271) But with recent advances in the biomedical sciences, a new crime against the dignity of the embryo as a human being is emerging: the use of foetal tissue as 'biological material' for transplantation. (ewtn.com)
  • Some tissue banks may appear disrespectful of the gifts they receive, tossing around terms like "gutter" tissue when referring to material that doesn't meet transplant standards but is then used for research on developing new products. (icij.org)
  • When I signed my donor card at the Department of Motor Vehicles, I was agreeing to give my organs and tissue for transplant or research. (icij.org)
  • Previously, human livers were only viable for an average of nine hours, but the new method of preservation maintains liver tissue for up to 27 hours, giving transplant doctors and patients a much longer timeframe to work with. (nih.gov)
  • National Donor Day is also a day to recognize those who have given and received the gift of life through organ, eye and tissue donation, are currently waiting for a lifesaving transplant, and those who died waiting because an organ was not donated in time. (donatelife.net)
  • In a traditional corneal transplant, the central part of the cornea is removed and a donor cornea is sutured in its place. (nih.gov)
  • Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, according to a study funded by the National Institutes of Health. (nih.gov)
  • Corneas from donors over age 71 perform slightly less well, but still remain healthy for the majority of transplant recipients after 10 years, the study found. (nih.gov)
  • We found that transplant success rates were similar across a broad range of donor ages. (nih.gov)
  • The corneas were given to patients, without respect to patient age, through a transplant procedure called penetrating keratoplasty, in which the central part of the damaged cornea is removed, and a full-thickness donor cornea is sutured in its place. (nih.gov)
  • That prompted an expansion of the study to determine if donor age would affect transplant viability 10 years after the procedure. (nih.gov)
  • Can Hair Transplant Use Cloned Hair from Someone Else's Donor Tissue? (bernsteinmedical.com)
  • If I need an organ or tissue transplant, what do I need to do? (clevelandclinic.org)
  • Keep up with the news and stories about donor families and transplant recipients. (lcnw.org)
  • That's why living donors are often family or friends of the transplant recipient. (nih.gov)
  • Ffrench-Constant & Mathews, 1994) Although there are scattered re ports of attempts to transplant neural tissues in mammals going back before the turn of the century, it is only two decades since several laboratories in the USA and Sweden first characterized the necessary conditions to yield reliable graft survival. (ewtn.com)
  • I have been listed an organ donor since about 1975, when it first was initiated in my state. (icij.org)
  • After eight months of research, I have learned a lot that might turn me off tissue donation. (icij.org)
  • Previously, residents were required to confirm the choice to register each time they renewed their license or state ID because prior decisions on organ, eye and tissue donation were not carried over. (donoralliance.org)
  • For more information on organ, eye and tissue donation, visit the About Donation section of our website. (donoralliance.org)
  • Registering your decision for organ and/or tissue donation is easy - all you need is your Saskatchewan Health Services Card number, first and last name and date of birth. (saskatchewan.ca)
  • The Surgeon General's Workshop on Increasing Organ Donation: Background Papers: 'Ninety-Four Percent Awareness and Still Not Enough Donors: Can Public Education Increase Organ Donation? (nih.gov)
  • The Surgeon General's Workshop on Increasing Organ Donation: Background Papers: 'Increasing Organ and Tissue Donation: What Are the Obstacles, What Are Our Options? (nih.gov)
  • Celebrated in April each year, NDLM features an entire month of local, regional and national activities to help encourage Americans to register as organ, eye and tissue donors and to celebrate those that have saved lives through the gift of donation. (greatermkemen.com)
  • As Americans, we can demonstrate our commitment to one another in the most difficult of circumstances through organ, tissue, stem cell, and blood donation. (greatermkemen.com)
  • There is no age limit for donors, and because some conditions and blood types are more common in certain ethnic and racial populations, the Department of Health and Human Services especially encourages minorities to consider donation. (greatermkemen.com)
  • Find out how you can register your wish to be considered for tissue donation. (dtbv.org.au)
  • Tissue donation can enhance and even save people's lives. (dtbv.org.au)
  • Donate Life America is committed to increasing the number of lives saved and healed through organ, eye and tissue donation. (donatelife.net)
  • Observed every year on February 14th, National Donor Day is an observance dedicated to spreading awareness and education about organ, eye and tissue donation. (donatelife.net)
  • National Donor Day is a time to focus on all types of donation- organ , eye , tissue , blood, platelets and marrow. (donatelife.net)
  • In addition to registering to be an organ, eye and tissue donor or contributing to the DLA cause , you can also download our National Donor Day graphics, Donor Day Flyer and Printable Valentine Cards (all available in English and Spanish) to raise awareness about donation throughout social media-link these images to other resources for your friends and followers to utilize within your local and online communities. (donatelife.net)
  • Explore more things you can do to support Donate Life America and advocate for organ, eye and tissue donation every day of the year. (donatelife.net)
  • As healthcare professionals across Florida call attention to the importance of organ donation in April during National Donate Life Month, a west Florida man is particularly grateful for one donor among the more than 11.8 million enrolled in the state's Joshua Abbott Organ and Tissue Donor Registry. (tampadispatch.com)
  • Organ donation is the act of taking healthy organs and tissues from one person and giving them to someone else. (nih.gov)
  • No. It's common for people to think that signing up to be an organ donor includes brain donation, but the purpose and the process are different. (nih.gov)
  • To learn more about the brain donation process, why many brains are needed from diverse populations and ages, and how to become a brain donor, visit NIA's article - Brain Donation: A Gift for Generations . (nih.gov)
  • Living donation has a different process than that of a deceased donor donation. (nih.gov)
  • Organ donation is the process of surgically removing an organ or tissue from one person (the organ donor) and placing it into another person (the recipient). (clevelandclinic.org)
  • There is no cost to the donor's family or estate for the donation of organs, tissue or eyes. (clevelandclinic.org)
  • Going forward, we will provide you with opportunities to honor your loved one and their gift of life, including a Gift of Life Donor Medal and invitations to our annual Donation Celebrations . (lcnw.org)
  • Last year, LifeCenter Northwest facilitated the donation of 921 organs from 310 deceased organ donors for life-saving transplants from across Alaska, Montana, northern Idaho and Washington. (lcnw.org)
  • Colorado is adopting the yes-carryover process for the state's organ, eye and tissue donor registry with changes to the process beginning September 15, 2017. (donoralliance.org)
  • This process ensures that the rights and responsibilities of those who have made their decision to join the Colorado Donor Registry known are in line with current state law. (donoralliance.org)
  • The yes-carryover process will ensure that the registry process meets the intent and requirements of the Uniform Anatomical Gift Act (UAGA), allowing residents who have made the choice to register as organ, eye and tissue donors to remain on the donor registry, without the hassle of renewing that choice repeatedly throughout their adult lives. (donoralliance.org)
  • The move to yes-carryover designation does not change residents' ability to remove their names from the donor registry at any time. (donoralliance.org)
  • For more information on what it means to join the donor registry, please visit our FAQ page . (donatelifecolorado.org)
  • Each organ or tissue donor can save many lives, and becoming one is simple: join your State's donor registry, indicate your decision on your driver's license, and inform loved ones of your decision. (greatermkemen.com)
  • Also be sure to keep your information, such as a current mailing address, up to date in your state's donor registry. (nih.gov)
  • You might join a donor registry. (clevelandclinic.org)
  • A registry is more than just an expression of interest in becoming a donor. (clevelandclinic.org)
  • For more information, go to www.lifebanc.org and click on donor registry. (clevelandclinic.org)
  • Donor registry information for any state might be obtained from www.donatelife.net . (clevelandclinic.org)
  • With the exception of transplants between identical twins, the only known way to accomplish this is to induce a specific non-responsive (tolerant) state, whereby the grafted tissue is ultimately not recognized as foreign. (nih.gov)
  • The change is also expected to help increase the number of registered donors in Colorado, therefore resulting in more lifesaving transplants, which will be a great public health benefit to all. (donoralliance.org)
  • Transplants rely on the generosity of organ, eye and tissue donors, and there are not enough donors to meet the need. (donatelife.net)
  • The Cornea Donor Study, funded by NIH's National Eye Institute (NEI), found that 10-year success rates remained steady at 75 percent for corneal transplants from donors 34-71 years old. (nih.gov)
  • In 2008, they reported that the five-year success rate was identical-86 percent-for transplants from donors aged 12-65 and those aged 66-75. (nih.gov)
  • This is compounded by the 'careful' terminology used in the journal articles, which serves to disguise the ugly truth that foetuses are being used as donors in experimental brain tissue transplants. (ewtn.com)
  • Graft versus host disease (GVHD) is an immune-mediated condition resulting from a complex interaction between donor and recipient adaptive immunity. (medscape.com)
  • Retrospective testing of blood donors using first generation tests such as immunodiffusion to detect HBsAg, found that 52%-69% of recipients of HBsAg-positive blood developed hepatitis B (8,9). (cdc.gov)
  • In addition, recipients of blood from paid donors were at higher risk of developing post-transfusion hepatitis than were recipients of blood from non-paid donors (10,11). (cdc.gov)
  • None of the recipients from the donors were reported to have any systemic adverse event after keratoplasty until the follow-up of 6 weeks. (bvsalud.org)
  • Through the UNOS Organ Center, organ donors are matched to waiting recipients 24 hours a day, 365 days a year. (clevelandclinic.org)
  • The Shavano Park Women hosted a Blood Drive with the South Texas Blood and Tissue Center (STBTC) on April 30, 2022, at Shavano Park City Hall. (spwnp.org)
  • In the United States, three-fourths of cornea donors are within this age range, and one-third of donors are at the upper end of the range, from 61-70 years old. (nih.gov)
  • Our study supports continued expansion of the corneal donor pool beyond age 65," said study co-chair Edward J. Holland, M.D., professor of ophthalmology at the University of Cincinnati and director of the Cornea Service at the Cincinnati Eye Institute. (nih.gov)
  • It involves removing a portion of the damaged cornea and grafting corneal tissue from a deceased donor in its place. (nih.gov)
  • The Cornea Donor Study was designed to address whether making use of donor corneas across the full range of ages available might help solve this problem," said Maryann Redford, D.D.S, M.P.H, a clinical research program director at NEI. (nih.gov)
  • One of the most commonly transplanted tissues is the cornea, the transparent covering over the eye. (nih.gov)
  • Transmission of HBV by transfusion of blood or blood products is rare because of routine screening of blood donors for HBsAg and because of current donor selection and deferral procedures. (cdc.gov)
  • Given current scrutiny of the blood donor deferral policy of Men who have Sex with Men (MSM), interpretations between MSM and non-MSM respondents also were compared. (cdc.gov)
  • Of 200 ocular tissues (100 corneal and 100 conjunctival) from the same 1 eye of 100 surgical-intended donors , between September 2020 and April 2021, the overall positivity rate for SARS-CoV-2 was â ¼1% (2/200). (bvsalud.org)
  • You're never too old to make a difference - as of 2021, the oldest organ donor in the United States was 92. (nih.gov)
  • A combination of more sensitive third-generation tests (reversed passive hemagglutination and radioimmunoassay (RIA)) for HBsAg screening and exclusive use of non-paid donors reduced the rate of post-transfusion hepatitis B to 0.3%-0.9%/transfusion recipient by the mid-1970s (12,13). (cdc.gov)
  • You can also read through our Stories of Hope , inspiring organ, eye and tissue donor and recipient stories. (donatelife.net)
  • Thus, organs, tissues, and semen obtained from HTLV-III/LAV antibody-positive persons must be considered as potentially infectious. (cdc.gov)
  • Transmission of human T-cell lymphotropic virus type III (HTLV-III) by artificial insemination by donor. (nih.gov)
  • We present here an analysis of lymphocyte localization and T cell subset composition across the human GI tract including mucosal sites (jejunum, ileum, colon), gut-associated lymphoid tissues (isolated lymphoid follicles (ILFs), Peyer's patches (PPs), appendix), and mesenteric lymph nodes (MLNs) from a total of 68 donors spanning eight decades of life. (nature.com)
  • 3 These age- and site-specific pathologies suggest spatial and temporal regulation of intestinal immunity, though in humans, the processes by which immune cell populations interact with and take up residence within the GI tract and gut-associated lymphoid tissues (GALT) are not known. (nature.com)
  • The most common options include patellar tendon, hamstring tendon, and donor tissue (allograft). (verywellhealth.com)
  • The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules. (ucsc.edu)
  • These guidelines address the use of tests for the hepatitis B and C viruses to screen donations of blood and plasma collected for transfusion or further manufacture into injectable products, as well as to screen donors of organs, tissues, and semen. (cdc.gov)
  • It is additionally recommended that blood or serum from donors of organs, tissues, or semen intended for human use be similarly tested and that the test result be used to evaluate the appropriate use of such materials from these donors. (cdc.gov)
  • Information from these studies could lead to the use of donor tissue to manipulate the recipient's immune system in a controlled and specific fashion, thereby increasing graft survival and improving the management of autoimmune diseases. (nih.gov)
  • This Request for Applications (RFA), Affecting Graft Survival With Donor Immune Tissue, is related to the priority areas of diabetes and chronic disabling diseases, and immunization and infectious diseases. (nih.gov)
  • The study (see NCT00006411 at https://www.clinicaltrials.gov/ ) was designed to compare graft survival rates for corneas from two donor age groups, aged 12-65 and aged 66-75. (nih.gov)
  • Registering as an organ, eye and tissue donor means you have made the decision to donate your organs, eyes and tissues at the time of your death, with the possibility to save others' lives. (donatelifecolorado.org)
  • Donors at least 17 years old (16 with parental consent) and in generally good health may be eligible to donate blood. (biobridgeglobal.org)
  • Inspired by 10-year-old Uvalde survivor Mayah Zamora and the 1-year anniversary of the school shooting, superintendents and top administrators from San Antonio and surrounding areas gathered to donate blood at South Texas Blood & Tissue on Tuesday. (biobridgeglobal.org)
  • During National Donate Life Month, we honor donors who provide others with a second chance for a healthy life and encourage more Americans to share this precious gift. (greatermkemen.com)
  • Visit OrganDonor.gov to learn more about the urgent need for donors and to find resources on how to donate. (greatermkemen.com)
  • The Donate Life America Tribute Wall is one way to honor loved ones on National Donor Day. (donatelife.net)
  • Can I donate an organ or tissue while I'm still living? (nih.gov)
  • Most donations occur after the donor has died, but it is possible to donate certain organs or tissue to someone in need while still living. (nih.gov)
  • Unfortunately, the need for organ donors is much greater than the number of people who actually donate. (clevelandclinic.org)
  • And if you donate tissues like blood cells, bone or corneas, you can help even more. (nih.gov)
  • In addition to organs, you can donate tissues. (nih.gov)
  • Screening blood donors for HBsAg began in 1969 and became mandatory in 1972. (cdc.gov)
  • Type O- is the universal donor, which means it can be given to people with any blood type. (biobridgeglobal.org)
  • Every blood center is struggling to maintain a stable blood supply," said Adrienne Mendoza, Chief Operating Officer, South Texas Blood & Tissue. (biobridgeglobal.org)
  • Every blood transfusion that is given to a patient in need comes from a volunteer donor, and we are calling on our community to come together. (biobridgeglobal.org)
  • Ryan has become a dedicated blood donor-paying it forward for the donations that have saved his daughter's life. (biobridgeglobal.org)
  • We are working closely with our hospitals to prepare for scheduled procedures that are likely to require transfusion support," said Dr. Samantha Gomez Ngamsuntikul, Associate Medical Director, South Texas Blood & Tissue. (biobridgeglobal.org)
  • Same-day appointments and walk-ins are available at the center's eight donor rooms, as well as at community blood drives. (biobridgeglobal.org)
  • I call upon health care professionals, volunteers, educators, government agencies, faith-based and community groups, and private organizations to join forces to boost the number of organ, tissue, blood, and stem cell donors throughout our Nation. (greatermkemen.com)
  • The questionnaire is used by most U.S. blood centers to screen potential blood donors. (cdc.gov)
  • When you become an organ A system of cells and tissues that perform specific tasks, such as pumping blood (heart), breathing (lungs) or removing waste from the blood (kidney). (nih.gov)
  • You can register to be an organ donor at the time you renew your driver's license or state ID at your local Department of Motor Vehicles. (nih.gov)
  • The tissue types collected were chosen based on their clinical significance, logistical feasibility and their relevance to the scientific goal of the project and the research community. (ucsc.edu)
  • The donor 's clinical history and cause of death were assessed for secondary analysis . (bvsalud.org)
  • When ICIJ began discussing how to write a story about the untraceable and opaque trade in human tissues, our intent was not to propel readers to toss out their donor cards. (icij.org)
  • Many tissue bank executives bring in big salaries, and that might seem to go against the spirit of the law, which expressly outlaws buying and selling human tissue. (icij.org)
  • The NIH Genotype-Tissue Expression (GTEx) project was created to establish a sample and data resource for studies on the relationship between genetic variation and gene expression in multiple human tissues. (ucsc.edu)
  • Transfusion-associated human T-lymphotropic virus type III/lymphadenopathy-associated virus infection from a seronegative donor--Colorado. (nih.gov)
  • Since human cells are especially sensitive, donor livers are stored above freezing at 4 degrees Celsius. (nih.gov)
  • Human tissue : ethical and legal issues. (who.int)
  • The purpose of this study was to evaluate the prevalence of SARS-CoV-2 in human postmortem ocular tissues of asymptomatic donors and its implications on our eye banking protocols . (bvsalud.org)
  • National Donor Day was started in 1998 by the Saturn Corporation and its partner, the United Auto Workers, and is supported by the U.S. Department of Health and Human Services. (donatelife.net)
  • This is an actual human valve taken from a donor and implanted in your heart (donor valve implantation). (medicinenet.com)
  • Across our country, we face a shortage of donors and an urgent need for help. (greatermkemen.com)
  • These guidelines are intended to serve as a resource to individuals and organizations involved in testing, counselling, and evaluating donors tested for these viruses, and are based on currently available knowledge. (cdc.gov)
  • This release is based on data from 17,382 tissue samples obtained from 948 adult post-mortem individuals. (ucsc.edu)
  • In previous studies funded by NIH, Martin Yarmush, Ph.D., director of the Center for Engineering in Medicine, Korkut Uygun, Ph.D., associate professor of surgery, and their collaborators at Massachusetts General Hospital (MGH), Boston, had developed new techniques that extended the time that rat liver (hepatic) tissue can be stored at subzero temperatures without damage. (nih.gov)
  • Both the ocular samples that tested positive were conjunctival biopsies (2/100, 2%), whereas corneal samples were negative (0/100, 0%) in both donors . (bvsalud.org)
  • But the 26-year-old was grateful his tissues, including skin, corneas, tendons and bones, could still go to people who needed them. (ihtoday.ca)
  • We continue to encourage residents to learn the facts and make an educated, lifesaving decision to register as organ, eye and tissue donors, and to discuss that decision with their families. (donoralliance.org)
  • When you register as an organ, eye and tissue donor, your registration remains in effect unless you change it. (donatelifecolorado.org)
  • Join us by participating in local events , sharing social media messages and encouraging others to register as donors. (donatelife.net)
  • How can someone register to be an organ donor? (nih.gov)
  • To decrease the potential for disease transmission, donors are screened for risk factors by medical history and for evidence of infection by specific testing. (cdc.gov)
  • None of the donors had a medical history suggestive of COVID infection or possible contact. (bvsalud.org)
  • Yes, some conditions such as an actively spreading cancer or infection, or heart disease, may prevent a person from becoming a donor. (nih.gov)
  • And tissue banks need to be able to attract talented people away from other sectors. (icij.org)
  • Experts say that the organs from one donor can save or help as many as 50 people. (medlineplus.gov)
  • People of all ages and background can be organ donors. (medlineplus.gov)
  • People of all ages should consider themselves potential donors. (clevelandclinic.org)
  • donor, you can save the lives of up to 8 people. (nih.gov)
  • This information should ultimately support decisions leading to appropriate tissue donor screening and testing considerations. (nih.gov)
  • This track shows median gene expression levels in 52 tissues and 2 cell lines, based on RNA-seq data from the GTEx final data release (V8, August 2019). (ucsc.edu)
  • WD 300-380 Connective Tissue Diseases (Note: Several numbers in the WD 300-330 Immune System Related Diseases area had already been cancelled with 2019 summer edition. (nih.gov)
  • When a Colorado resident registers as a donor, that decision no longer needs to be proactively renewed and will remain in effect unless they change it. (donoralliance.org)
  • Study objectives were to assess question interpretation, understand potential donors' processes for formulating a response, identify question design problems that could increase inaccurate reports, and compare interpretations between those in different geographic regions. (cdc.gov)
  • Tissue samples were obtained using the GTEx standard operating procedures for informed consent and tissue collection, in conjunction with the National Cancer Institute Biorepositories and Biospecimen . (ucsc.edu)
  • In Australia, skin can only be donated from deceased donors. (dtbv.org.au)
  • Donated skin tissue can be used as grafts for burn victims or for reconstruction after surgery. (nih.gov)
  • The scientific goal of the GTEx project required that the donors and their biospecimen present with no evidence of disease. (ucsc.edu)
  • Tissue banks overseas have allegedly taken tissue without consent. (icij.org)
  • It's a way to legally give consent for the anatomical gift of organs, tissue and eyes. (clevelandclinic.org)
  • After you sign up to be an organ donor, be sure to tell your family and friends. (nih.gov)
  • Let your family members and loved ones know you'd like to be a donor. (clevelandclinic.org)
  • You might also want to tell your family healthcare provider, lawyer and religious leader that you'd like to be a donor. (clevelandclinic.org)
  • Tissue colors were assigned to conform to the GTEx Consortium publication conventions. (ucsc.edu)
  • Many thanks to the donors for giving the "Gift of Life" that will benefit many patients. (spwnp.org)
  • Montana governor honors organ donors at "Gift of Life" event in Helena. (lcnw.org)
  • Donor cells can be transferred from one person to another without being rejected. (bernsteinmedical.com)
  • Since repeat hair implantations did not provoke the typical rejection responses, even though the donor was of the opposite sex and had a significantly different genetic profile, this indicates that the dermal sheath cells have a special immune status and that the lower hair follicle is one of the body's 'immune privileged' sites. (bernsteinmedical.com)
  • In the mucosa, tissue resident memory T cells develop during childhood, and persist in high frequencies into advanced ages, while T cell composition changes with age in GALT and MLN. (nature.com)
  • The OPO decides if you're a possible donor based on your medical and social history. (nih.gov)
  • Do any medical conditions exclude someone from becoming an organ donor? (nih.gov)
  • When a person dies, they are evaluated for donor suitability based on their medical history and age. (clevelandclinic.org)
  • By becoming an organ donor, does this mean that I wouldn't be eligible to receive the best medical care possible? (clevelandclinic.org)
  • The recovery of organs, tissue and eyes is a surgical procedure performed by trained medical professionals. (clevelandclinic.org)
  • However, his tissues were rejected when he died last November, said his mother Cindy Gates-Dee, who learned from reading her son's medical records that his "homosexual status," as noted on a screening form by a tissue specialist, meant he was declined as a high-risk donor because he'd had sex with another man in the last five years. (ihtoday.ca)
  • Donor corneas were provided by 43 eye banks, and met the quality standards of the Eye Bank Association of America. (nih.gov)