Tissue Transplantation
Medical Informatics Applications
Tissue Preservation
Cryopreservation
Transplantation, Homologous
Tissue Donors
Tissue and Organ Procurement
Organ Transplantation
Automobile Driver Examination
Biometric Identification
Ethics, Medical
Umbilical cord blood transplant from unrelated HLA-mismatched donors in children with high risk leukemia. (1/299)
In the last 3 years, 14 children with high-risk leukemia (11 ALL, 2 AML and 1 CML) underwent cord blood transplantation from unrelated HLA-mismatched donors at a median of 99 days from the start of search. Eight patients were transplanted in second CR, one in accelerated phase, three at relapse and two patients in first CR. Conditioning regimen (fractionated TBI, etoposide, CY and anti-lymphocyte serum) and prophylaxis of GVHD (CsA and 6-methylprednisolone) were identical for all patients. Neutrophils >0.5x10(9)/l were reached at a median of 33 days from transplant, but in four cases we observed an autologous hematopoietic reconstitution (three spontaneous, one after autologous BM rescue). Acute and chronic GVHD were observed in 10/14 and 3/8 evaluable cases, respectively. Three patients died of transplant-related toxicity and three patients relapsed. The probabilities of event-free, disease-free and overall survival were 50, 53 and 64%, respectively. Cord blood transplant from HLA-mismatched unrelated donor is a valid option for the treatment of children with high-risk leukemia. With our eligibility criteria, conditioning regimen and prophylaxis of graft-versus-host disease, the main obstacles to successful transplant were represented by graft failure and fatal acute GVHD. (+info)Supplying commercial biomedical companies from a human tissue bank in an NHS hospital--a view from personal experience. (2/299)
NHS histopathology laboratories are well placed to develop banks of surgically removed surplus human tissues to meet the increasing demands of commercial biomedical companies. The ultimate aim could be national network of non-profit making NHS tissue banks conforming to national minimum ethical, legal, and quality standards which could be monitored by local research ethics committees. The Nuffield report on bioethics provides ethical and legal guidance but we believe that the patient should be fully informed and the consent given explicit. Setting up a tissue bank requires enthusiasm, hard work, and determination as well as coordination between professionals in the NHS trust and in the commercial sector. The rewards are exiting new collaborations with commercial biomedical companies which could help secure our future. (+info)Cancer risk estimates for family members of a population-based family registry for breast and ovarian cancer. (3/299)
Population-based breast and ovarian cancer family registries can facilitate studies to evaluate genetic and environmental factors in the etiology of these malignancies. The purpose of this study is to describe what is, as far as we know, the first population-based breast and ovarian cancer family registry and to estimate breast and ovarian cancer risk in relatives of breast and ovarian cancer probands. Population-based consecutive incident cases of breast and ovarian cancer were invited to participate in the University of California, Irvine breast and ovarian family registry. In this study, we report data on 1567 breast cancer and 328 ovarian cancer probands. The operational components of this family registry include enrollment of probands, family history interviewing, confidentiality, pathology, verification and review, biospecimen bank, statistical/genetic analysis, and special studies on positional cloning of known genes. All of the components are tracked through the University of California, Irvine Genetic Research Information System. In non-Hispanic-white breast cancer probands, relative risk (RR) of breast cancer in mothers and sisters is significantly elevated [RR = 1.7 and 95% confidence interval (CI) = 1.4-2.0 and RR = 2.8 and 95% CI = 2.3-3.3, respectively]. In families of ovarian cancer probands, mothers are at increased risk of ovarian cancer (RR = 4.6; 95% CI, 2.1-8.7). RR of breast cancer in mothers of Hispanic breast cancer probands is significantly elevated (RR = 4.9; 95% CI, 2.6-8.5). No elevation of breast or ovarian cancer risk was observed among relatives of Asian probands. In general, there is a decrease in RR among mothers and sisters with increase in age of onset of probands. In second-degree relatives and first cousins, the breast cancer hazards ratios increase with increase in the number of affected first-degree relatives and decrease with increase in age at onset of the proband. (+info)The mechanical properties of fresh and cryopreserved arterial homografts. (4/299)
OBJECTIVES: To assess the effect of cryopreservation on the elasticity and compliance of arterial allografts. MATERIALS AND METHODS: Iliofemoral segments of arteries and veins harvested from multiorgan donors were divided into two groups: fresh-control, tested for 24 hours after harvesting, and cryopreserved in liquid nitrogen after pretreatment with 20% dimethylsulphoxide and stored for an average time of 22 days. Vessel wall elastic properties were evaluated from the stress-strain relationship in a specially designed test cell fixed to the Instron Universal Testing Machine. RESULTS: The elastic modulus of the artery control group (1.54+/-0.33 MPa, n=20) was not significantly different from the cryopreserved group (1.69+/-0.61 MPa, n=15). Similarly, values for unfrozen veins (3.11+/-0.65 MPa, n=47) were not significantly different from those of frozen samples (2.71+/-0.85 MPa, n=38). Control compliance (6. 86+/-1.79x10(-5)%/Pa, for arteries; 3.84+/-0.81x10(-5)%/Pa, for veins) was similar to that of the cryopreserved group (6.66+/-1. 80x10(-5)%/Pa, for arteries; 4.16+/-1.21x10(-5)%/Pa, for veins). CONCLUSIONS: Cryopreservation maintains the important elastic properties of arterial and venous allografts during average storage time of 22 days. (+info)Cadaver donor screening for infectious agents in solid organ transplantation. (5/299)
The transmission of infection by a cadaver donor organ can result not only in loss of the allograft but also in death of the immunosuppressed recipient. Despite the shortage of cadaver organ donors, every donor must be evaluated thoroughly for the potential transmission of infectious disease, because the consequences of the organ donor events can have a profound effect on the transplant outcome. This review summarizes current knowledge about serological screening of organ donors to determine the suitability of organs from cadaver donors for transplantation. (+info)Polymerase chain reaction detection of Kaposi's sarcoma-associated herpesvirus-optimized protocols and their application to myeloma. (6/299)
Since its discovery in 1994, KSHV (also called human herpesvirus-8 or HHV8) has been implicated in a variety of disorders. Although the association of KSHV with Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease has been well established, its presence in some other diseases, such as multiple myeloma, remains controversial. Because most KSHV studies are based on polymerase chain reaction (PCR) analysis, the conflicting data may be attributable to variations in the methods, primer sets, and target sequences selected. To establish an efficient and reliable PCR approach for KSHV detection we designed eight sets of primers to six regions (ORFK1, ORFK2, ORFK9, ORK26, ORF72, and ORF74) of the KSHV genome using appropriate database and software. The detection sensitivity of these primers was carefully assessed and their reliability was strictly validated in a series of positive (15 KS and PEL samples) and negative (16 lymphoid tissues) controls. We found that primer sets to the ORFK9 region showed the highest sensitivity, whereas primer sets to ORFK1 and ORF74 showed the lowest sensitivity. Primer sets to ORFK9, ORF26 and ORF72 regions detected all of the positive cases, whereas other primer sets showed varying detection rates or nonspecific bands. All 16 negative controls were negative with all primer sets. However, six of 16 negative controls became positive when we used nested PCR targeting ORF26. Therefore, multiple target KSHV sequences increase the detection efficiency, while nested PCR protocols are likely to introduce false positivity. Using ORFK9, ORF26 and ORF72 primer sets, we screened bone marrow biopsies from 18 cases of multiple myeloma, and failed to detect any KSHV sequences. This finding supports the conclusion that KSHV is not associated with multiple myeloma. Indeed, our results further confirm that although KSHV is universally present in Kaposi's sarcoma and primary effusion lymphoma, it is not ubiquitious. (+info)Preservation of RNA for functional genomic studies: a multidisciplinary tumor bank protocol. (7/299)
Few human tumors are collected such that RNA is preserved for molecular analysis. Completion of the Human Genome Project will soon result in the identification of more than 100,000 new genes. Consequently, increasing attention is being diverted to identifying the function of these newly described genes. Here we describe a multidisciplinary tumor bank procurement protocol that preserves both the integrity of tissue for pathologic diagnosis, and the RNA for molecular analyses. Freshly excised normal skin was obtained from five patients undergoing wound reconstruction following Mohs micrographic surgery for cutaneous neoplasia. Tissues treated for 24 hours with RNAlater were compared histologically and immunohistochemically to tissues not treated with RNAlater. Immunohistochemical stains studied included: CD45, CEA, cytokeratin AE1/3, vimentin, S-100, and CD34 on formalin-fixed, paraffin embedded tissue and CD45 staining of frozen tissue. Slides were blinded and evaluated independently by three pathologists. The histologic and immunohistochemical parameters of tissue stored in RNAlater were indistinguishable from tissue processed in standard fashion with the exception of S-100 stain which failed to identify melanocytes or Langerhan's cells within the epidermis in any of the RNAlater-treated tissues. Interestingly, nerve trunks within the dermis stained appropriately for S-100. Multiple non-cutaneous autopsy tissues were treated with RNAlater, formalin, liquid nitrogen (LN2), and TRIzol Reagent. The pathologists were unable to distinguish between tissues treated with RNAlater, formalin, or frozen in LN2, but could easily distinguish tissues treated with TRIzol Reagent because of extensive cytolysis. RNA was isolated from a portion of the tissue treated with RNAlater and used for molecular studies including Northern blotting and microarray analysis. RNA was adequate for Northern blot analysis and mRNA purified from RNAlater-treated tissues consistently provided excellent templates for reverse transcription and subsequent microarray analysis. We conclude that tissues treated with RNAlater before routine processing are indistinguishable histologically and immunohistochemically from tissues processed in routine fashion and that the RNA isolated from these tissues is of high quality and can be used for molecular studies. Based on this study, we developed a multidisciplinary tumor bank procurement protocol in which fresh tissue from resection specimens are routinely stored in RNAlater at the time of preliminary dissection. Thus, precious human tissue can be utilized for functional genomic studies without compromising the tissue's diagnostic and prognostic qualities. (+info)Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion. (8/299)
The dramatic opportunities presented by comprehensive gene profiling technologies are curbed by the problem of segregating these large amounts of gene expression data into meaningful categories for study. This is particularly evident in infiltrating carcinomas of the pancreas, in which global gene expression data primarily mirrors the prominent desmoplastic response to the infiltrating neoplasm. In an effort to better characterize the gene expression of invasive pancreatic cancers and their associated desmoplastic response, we performed in situ hybridization on pancreatic cancer tissues to characterize the expression of 12 genes identified by serial analysis of gene expression as highly expressed in invasive pancreatic cancer tissues but not in pancreatic cancer cell lines. In situ hybridization demonstrated that eight genes were expressed within the stromal and/or angioendothelial cells of the desmoplastic response to the invasive tumor, and four of these genes were specifically expressed by the stromal cells immediately adjacent to the invasive neoplastic epithelium, suggesting regional differences in gene expression within the host desmoplastic response. In contrast, four genes were specifically expressed by the invasive neoplastic epithelium, indicating important differences between in vivo and in vitro gene expression of human epithelial neoplasms. We have identified a highly organized structure of gene expression within the host stromal response to invasive pancreatic cancer that may reflect tumor-host communication and serve as a target for therapeutic intervention. (+info)A Tissue Bank is a specialized facility that collects, stores, and distributes human tissues for medical research, transplantation, or therapeutic purposes. These tissues can include organs, bones, skin, heart valves, tendons, and other bodily tissues that can be used for various medical applications.
Tissue banks follow strict regulations and guidelines to ensure the safety and quality of the tissues they handle. They implement rigorous screening and testing procedures to minimize the risk of disease transmission and maintain the integrity of the tissues. The tissues are stored under specific conditions, such as temperature and humidity, to preserve their function and viability until they are needed for use.
Tissue banks play a critical role in advancing medical research and improving patient outcomes by providing researchers and clinicians with access to high-quality human tissues for study and transplantation.
A bone bank is a facility or organization that collects, stores, and distributes bone grafts or bone-graft substitutes for use in medical procedures. These bones or bone substitutes can come from donors (cadavers or living donors) or can be synthetic. The bones are typically cleaned, sterilized, and processed to make them safe for transplantation before being stored in the bank. Bone banks are regulated by various national and international organizations to ensure the safety and quality of the bone grafts they provide.
Bone banks play an important role in orthopedic and dental surgery, as well as in reconstructive surgery, by providing a source of bone tissue that can be used to repair or rebuild damaged or missing bones. The use of bone grafts from bone banks has been shown to improve outcomes in many surgical procedures, including spinal fusion, joint replacement, and maxillofacial reconstruction.
Tissue transplantation is a medical procedure where tissues from one part of the body or from another individual's body are removed and implanted in a recipient to replace damaged, diseased, or missing tissues. The tissues may include skin, bone, tendons, ligaments, heart valves, corneas, or even entire organs such as hearts, lungs, livers, and kidneys.
The donor tissue must be compatible with the recipient's body to reduce the risk of rejection, which is the immune system attacking and destroying the transplanted tissue. This often requires matching certain proteins called human leukocyte antigens (HLAs) found on the surface of most cells in the body.
Tissue transplantation can significantly improve a patient's quality of life or, in some cases, save their life. However, it does carry risks such as infection, bleeding, and rejection, which require careful monitoring and management.
Medical Informatics Applications refer to the use of information technologies and computer systems in the field of healthcare and medicine, for the collection, storage, processing, retrieval, and exchange of health-related data and information. These applications support clinical decision-making, research, education, management, and other areas of healthcare delivery, by providing timely and accurate information to healthcare professionals, patients, and other stakeholders. Examples of medical informatics applications include electronic health records (EHRs), computerized physician order entry (CPOE) systems, clinical decision support systems (CDSSs), telemedicine systems, and health information exchange (HIE) platforms.
Tissue preservation is the process of preventing decomposition or autolysis (self-digestion) of tissues after they have been removed from a living organism. This is typically achieved through the use of fixatives, such as formaldehyde or glutaraldehyde, which stabilize proteins and other cellular structures by creating cross-links between them. Other methods of tissue preservation include freezing, dehydration, and embedding in paraffin or plastic resins. Properly preserved tissues can be stored for long periods of time and used for various research and diagnostic purposes, such as histology, immunohistochemistry, and molecular biology studies.
Cryopreservation is a medical procedure that involves the preservation of cells, tissues, or organs by cooling them to very low temperatures, typically below -150°C. This is usually achieved using liquid nitrogen. The low temperature slows down or stops biological activity, including chemical reactions and cellular metabolism, which helps to prevent damage and decay.
The cells, tissues, or organs that are being cryopreserved must be treated with a cryoprotectant solution before cooling to prevent the formation of ice crystals, which can cause significant damage. Once cooled, the samples are stored in specialized containers or tanks until they are needed for use.
Cryopreservation is commonly used in assisted reproductive technologies, such as the preservation of sperm, eggs, and embryos for fertility treatments. It is also used in research, including the storage of cell lines and stem cells, and in clinical settings, such as the preservation of skin grafts and corneas for transplantation.
Homologous transplantation is a type of transplant surgery where organs or tissues are transferred between two genetically non-identical individuals of the same species. The term "homologous" refers to the similarity in structure and function of the donated organ or tissue to the recipient's own organ or tissue.
For example, a heart transplant from one human to another is an example of homologous transplantation because both organs are hearts and perform the same function. Similarly, a liver transplant, kidney transplant, lung transplant, and other types of organ transplants between individuals of the same species are also considered homologous transplantations.
Homologous transplantation is in contrast to heterologous or xenogeneic transplantation, where organs or tissues are transferred from one species to another, such as a pig heart transplanted into a human. Homologous transplantation is more commonly performed than heterologous transplantation due to the increased risk of rejection and other complications associated with xenogeneic transplants.
A tissue donor is an individual who has agreed to allow organs and tissues to be removed from their body after death for the purpose of transplantation to restore the health or save the life of another person. The tissues that can be donated include corneas, heart valves, skin, bone, tendons, ligaments, veins, and cartilage. These tissues can enhance the quality of life for many recipients and are often used in reconstructive surgeries. It is important to note that tissue donation does not interfere with an open casket funeral or other cultural or religious practices related to death and grieving.
Tissue and organ procurement is the process of obtaining viable tissues and organs from deceased or living donors for the purpose of transplantation, research, or education. This procedure is performed by trained medical professionals in a sterile environment, adhering to strict medical standards and ethical guidelines. The tissues and organs that can be procured include hearts, lungs, livers, kidneys, pancreases, intestines, corneas, skin, bones, tendons, and heart valves. The process involves a thorough medical evaluation of the donor, as well as consent from the donor or their next of kin. After procurement, the tissues and organs are preserved and transported to recipients in need.
Organ transplantation is a surgical procedure where an organ or tissue from one person (donor) is removed and placed into another person (recipient) whose organ or tissue is not functioning properly or has been damaged beyond repair. The goal of this complex procedure is to replace the non-functioning organ with a healthy one, thereby improving the recipient's quality of life and overall survival.
Organs that can be transplanted include the heart, lungs, liver, kidneys, pancreas, and intestines. Tissues such as corneas, skin, heart valves, and bones can also be transplanted. The donor may be deceased or living, depending on the type of organ and the medical circumstances.
Organ transplantation is a significant and life-changing event for both the recipient and their families. It requires careful evaluation, matching, and coordination between the donor and recipient, as well as rigorous post-transplant care to ensure the success of the procedure and minimize the risk of rejection.
The Automobile Driver Examination is a medical definition that refers to the process of evaluating an individual's physical and mental fitness to operate a motor vehicle. The examination typically includes a series of tests designed to assess the person's vision, hearing, reaction time, cognitive abilities, and overall health status.
The purpose of the examination is to ensure that drivers are capable of operating their vehicles safely and reducing the risk of accidents on the road. In many jurisdictions, driver examinations are required for individuals seeking to obtain a new driver's license or renew an existing one, particularly for those in certain age groups or with medical conditions that may affect their ability to drive.
The examination is usually conducted by a licensed healthcare professional, such as a doctor or nurse practitioner, who has been trained to assess the driver's fitness to operate a motor vehicle. The results of the examination are then used to determine whether the individual is medically fit to drive and what, if any, restrictions or accommodations may be necessary to ensure their safety and the safety of others on the road.
Biometric identification is the use of automated processes to identify a person based on their unique physical or behavioral characteristics. These characteristics, known as biometrics, can include fingerprints, facial recognition, iris scans, voice patterns, and other distinctive traits that are difficult to replicate or forge. Biometric identification systems work by capturing and analyzing these features with specialized hardware and software, comparing them against a database of known individuals to find a match.
Biometric identification is becoming increasingly popular in security applications, such as access control for buildings and devices, border control, and law enforcement. It offers several advantages over traditional methods of identification, such as passwords or ID cards, which can be lost, stolen, or easily replicated. By contrast, biometric traits are unique to each individual and cannot be easily changed or duplicated.
However, there are also concerns around privacy and the potential for misuse of biometric data. It is important that appropriate safeguards are in place to protect individuals' personal information and prevent unauthorized access or use.
Medical ethics is a branch of ethics that deals with moral issues in medical care, research, and practice. It provides a framework for addressing questions related to patient autonomy, informed consent, confidentiality, distributive justice, beneficentia (doing good), and non-maleficence (not doing harm). Medical ethics also involves the application of ethical principles such as respect for persons, beneficence, non-maleficence, and justice to specific medical cases and situations. It is a crucial component of medical education and practice, helping healthcare professionals make informed decisions that promote patient well-being while respecting their rights and dignity.
Clinical ethics refers to the branch of applied ethics that deals with ethical issues in clinical settings, such as hospitals and other healthcare facilities. It involves the application of moral principles and values to decision-making in clinical practice, with the aim of promoting patient autonomy, beneficence, non-maleficence, and justice.
Clinical ethics often involves addressing complex ethical dilemmas that arise in the context of patient care, such as end-of-life decisions, informed consent, confidentiality, resource allocation, and research involving human subjects. Clinical ethicists may work as part of an institutional ethics committee or provide consultation services to healthcare providers, patients, and families facing ethical challenges.
The principles of clinical ethics are grounded in respect for patient autonomy, which includes the right to make informed decisions about their own care. Beneficence refers to the obligation to act in the best interests of the patient, while non-maleficence involves avoiding harm to the patient. Justice requires fair and equitable distribution of healthcare resources and respect for the rights and dignity of all patients.
Effective clinical ethics decision-making also involves careful consideration of contextual factors, such as cultural differences, religious beliefs, and social values, that may influence ethical judgments in particular cases. Clinical ethicists use a variety of methods to analyze ethical issues, including case consultation, ethical analysis frameworks, and moral deliberation processes that involve all stakeholders in the decision-making process.
Tissue bank
Certified Tissue Bank Specialist
American Association of Tissue Banks
Brown adipose tissue
Biomedical tissue
Cord blood bank
Dana Shires
Platelet-rich fibrin
Cooperative Human Tissue Network
Autism Speaks
Caisis
Transcription error
Yongyudh Vajaradul
Meniscus transplant
Cell bank
Decompressive craniectomy
Nasal chondrocytes
Institute of Food and Radiation Biology
Sri Lanka Eye Donation Society
Hudson Silva
Enikő Kubinyi
Tissue-pack marketing
Methuselah Foundation
Breast Cancer Campaign
Terry Gross
Imperial College Faculty of Medicine
Eye bank
AIM at Melanoma Foundation
Sperm donation laws by country
Brain Injury Research Institute
Tissue bank - Wikipedia
New Human Tissue Bank 'A Tremendous Research Resource' | ScienceDaily
Development of the National Marine Mammal Tissue Bank | NIST
Multiple Sclerosis and Parkinson's Tissue Bank | ALZFORUM
LifeNet Health | American Association of Tissue Banks
Regional map of available samples - Pacific Specimen Tissue Bank
Information for research tissue banks | Human Tissue Authority
PART 470 SPERM BANK AND TISSUE BANK CODE : Sections Listing
National Marine Mammal Tissue Bank and Quality Assurance Program::protocols, inventory, and analytical results | NIST
Bulletin 22-4 | American Association of Tissue Banks
Citation Form | CELL-AND-TISSUE-BANKING | Painting | Citation Machine
mesothelioma tissue bank Archives | Surviving Mesothelioma
Tissue bank | CCDHB
Europe Launches First Mesothelioma Tissue Bank
Maternal Research Placenta & Cord Blood Bank | MCW Tissue Bank | Pathology & Laboratory Medicine | Medical College of Wisconsin
Leukemia Tissue Bank Shared Resource | OSUCCC - James
Cetacean Tissue Bank | Natural History | National Museum of Ireland
LifeLink Foundation Tissue Processing and Banking Facility - RS&H, Inc
Susan G. Komen Tissue Bank - IU Simon Cancer Center
What Is Soft Tissue Mobilization | East Bank Chicago
Blood & Tissue Banking | Rees Scientific
'Brain Tumour Tissue Bank: The brainstrust Proposal' published in a number of journals - Brainstrust, brain tumour...
THE EDINBURGH BRAIN & TISSUE BANK FOR INVESTIGATION OF SUDDEN DEATH - University of Edinburgh Research Explorer
Request Tissue/ Surgeon Portal | Rocky Mountain Lions Eye Bank
Food Industry Spotlight: Irving Tissue - Regional Food Bank of Northeastern New York
Cord Blood & Cord Tissue Banking Dinner Event - March 26 | Familycfa
es-BANK Tissue List
Consent IUSCC Tissue Bank
es-BANK Tissue List
Tissue Bank - Institute of Pathology
Ocular tissue5
- TBI/Tissue Banks International is a non-profit, non-governmental network of eye and tissue banks and the largest provider of ocular tissue in the world. (mightycause.com)
- Developed in collaboration with Sydney University Save Sight Institute, and under the governance of the NSW Organ and Tissue Donation Service, the Australian Ocular Biobank (AOB) will allow for the long term storage of a range of ocular tissue for research purposes from living and deceased donors. (nsw.gov.au)
- The aim of this study was to describe the harnessing of corneas captured and processed for transplantation in an ocular tissue bank in north-eastern Brazil . (bvsalud.org)
- Further studies are required on the reasons for discarding corneas and clarifications as to the conduct of professionals when processing corneas , considering the increase in the quantity of donors and the elevated number of discarded ocular tissue . (bvsalud.org)
- The ocular tissue where these tumors arise, the uvea, is a densely pigmented layer that lies for the most part between the sclera and the retina. (medscape.com)
Donors5
- Tissue is then taken from healthy volunteers, from patients donating samples following diagnostic testing and surgery, or from transplant and cadaveric donors. (sciencedaily.com)
- Ethical approval for a research tissue bank offers additional assurance to end user researchers, donors and the public that its operations meet the highest ethical standards. (hta.gov.uk)
- RMLEB recovers eye tissue from deceased donors in Colorado and Wyoming, is an accredited member of the Eye Bank Association of America, and is registered with the U.S. Food & Drug Administration. (corneas.org)
- Cornea tissue for PKP is generally from donors 10-75 with an endothelial cell count grater than 2500. (safetygraft.com)
- The NSW Tissue Bank incorporating the Lions NSW Eye Bank and NSW Bone Bank, is a state-wide service for the identification and coordination of eye, musculoskeletal, skin, and amnion donors. (nsw.gov.au)
Transplantation5
- A tissue bank is an establishment that collects and recovers human cadaver tissue for the purposes of medical research, education and allograft transplantation. (wikipedia.org)
- Online learning and education surrounding all aspects of tissue donation, tissue banking, research, and transplantation. (aatb.org)
- The mission of TBI/Tissue Banks International is to relieve human suffering by facilitating the donation, retrieval, processing, and equitable distribution of corneal and other human cadaveric tissue for transplantation, research, education, and other medical needs worldwide. (mightycause.com)
- To advance TBI as a premiere allograft tissue provider and a magnet for future innovations in biologics and tissue transplantation: a recognized leader in the field of tissue banking. (mightycause.com)
- West Nile Virus transmission through tissue transplantation, for instance, skin, muscle, or connective tissues, has not been identified, and the risk for transmission by this route is not known. (cdc.gov)
Komen Tissue Bank5
- For the study, they used specimens donated to the Komen Tissue Bank by African American women. (iu.edu)
- The program, directed by IU's First Lady Laurie Burns McRobbie (pictured here between KTB COO Jill Henry, and KTB Executive Director Anna Maria Storniolo, M.D.), has partnered with our Komen Tissue Bank team once again to host 2 events for IU alumni highlighting breast cancer research at Indiana University. (iu.edu)
- At each event, Dr. Storniolo shared the Komen Tissue Bank story and the power of normal tissue in the fight against breast cancer. (iu.edu)
- Through my friend and neighbor, an opportunity to be the Data Specialist and Program Assistant at the Komen Tissue Bank became my next career move in the summer of 2018. (iu.edu)
- I am really looking forward to learning everything I can here at the Komen Tissue Bank. (iu.edu)
Researchers11
- The University of Bradford has unveiled a new facility to provide UK biomedical researchers access to a wide range of human tissue and tissue products. (sciencedaily.com)
- The tumour bank supplied specimens vital to cancer research to locally-based researchers. (sciencedaily.com)
- Our ability to provide researchers directly with ethical approval will ensure a very efficient process that enables them to receive human tissue in a significantly reduced time frame. (sciencedaily.com)
- A hospital in Cambridge, England has opened Europe's first dedicated mesothelioma tissue bank, an important step forward for doctors and researchers working to develop a treatment for this aggressive cancer. (survivingmesothelioma.com)
- The MCW Maternal Research Placenta & Cord Blood Bank is an extension of the MCW Tissue Bank and serves to support physicians and medical researchers across campus in the investigation of various conditions and potential treatments. (mcw.edu)
- Therefore, Banking cord blood and making it available to researchers is essential to future research that could potentially extend many lives. (mcw.edu)
- At Santa Barbara Botanic Garden's Tissue Bank, established in 2018, we aim to preserve the raw material from which researchers can isolate genomic DNA for use in a variety of investigations. (sbbotanicgarden.org)
- As is expected with other collection efforts, researchers must have acquired the appropriate permits and practiced responsible collection methods when collecting tissue for the Garden. (sbbotanicgarden.org)
- The tissue samples are made available without charge to qualified researchers or research laboratories worldwide. (msdiscovery.org)
- The virtual bank also allows for collaboration between researchers from different institutions and disciplines, helping to advance knowledge and understanding of this complex disease. (cdc.gov)
- Researchers can use the tissue bank to test potential new therapies and to identify patients who may be good candidates for clinical trials. (cdc.gov)
Organs and tissues2
- The LifeLink Foundation attempts to work sensitively, diligently and compassionately with donor families to facilitate the donation of desperately needed organs and tissues for waiting patients. (rsandh.com)
- Optimal blood circulation is essential for overall well-being, since it ensures oxygen and nutrients reach necessary organs and tissues. (phildickercommercials.co.uk)
Postmortem4
- The bank collects tissues and fluid from the entire brain and spinal cord, a sample of postmortem CSF, a small sample of muscle from the back, and a limited number of muscle, pituitary and pineal glands, and gut samples. (alzforum.org)
- Postmortem tissue donation for research: a positive opportunity? (ed.ac.uk)
- HBTB also has brain samples (mainly from the cerebral cortex) with zero-hour postmortem delay, i.e., tissue samples were taken during neurosurgery and frozen on dry ice right in the surgical room. (msdiscovery.org)
- Virus RNA, viral antigen, or infectious viral particles could be detected in postmortem tissues. (cdc.gov)
Soft tissues2
- A chiropractor, massage therapist, or other trained professional uses their hands to apply varying degrees of pressure and different stroke patterns directly against your soft tissues. (eastbankchiropractic.com)
- This is an injury to the soft tissues of the neck, such as its muscles and tendons. (eastbankchiropractic.com)
Tumor5
- Pathology samples from 1,000 mesothelioma patients will be used to build a Tissue Microarray, which will allow scientists to process and evaluate hundred of tumor cell samples at once. (survivingmesothelioma.com)
- After surgeons removed as much of the visible mesothelioma tumor and surrounding tissue as possible, patients received 50Gy of radiation to the effected side of their chest, delivered in 25 fractions. (survivingmesothelioma.com)
- Since 1989 unfixed tissue samples from tumor specimens and corresponding non-tumourous tissues are systematically collected, frozen in liquid nitrogen (N2), stored at the Institute of Pathology at the Technical University of Munich, and made available for biomedical research. (tum.de)
- Currently, about 28.000 samples from about 18.000 patients are stored in our tissue bank, from which about 15.000 samples are malignant tumor tissues and about 13.000 samples are non-neoplastic tissues or benign samples. (tum.de)
- Erosion of the tumor into blood vessels in adjacent tissues, or areas of necrosis within the tumor, can lead to hyphema or vitreous hemorrhage. (medscape.com)
Specimens1
- You are invited to participate in a long-term program to collect biological specimens (tissue, blood pleural fluid, ascites fluid, breast milk, hair and nail clippings) for future research purposes. (iu.edu)
Mesobank UK1
- The 'Mesobank UK' tissue bank recently launched at Papworth Hospital in Cambridge (a part of Cambridge University Health Partners) will provide vital tissue samples and anonymous, detailed clinical information which can be used to conduct research studies. (survivingmesothelioma.com)
Association of America2
- We are registered with the US Food & Drug Administration (FDA) and accredited by the Eye Bank Association of America (EBAA) , the gold standard for eye banking. (corneas.org)
- We are members of the Eye Bank Association of America and all tissue recovered from eye banks accredited by the Eye Bank Association of America. (safetygraft.com)
Collects1
- With the patient's consent, the NMVB collects and stores de-identified tissue and blood samples from patients with mesothelioma, as well as from patients who have been exposed to asbestos but have not developed the disease. (cdc.gov)
Donor3
- This report describes a cognitive interviewing study conducted by the Questionnaire Design Research Laboratory (QDRL) at the National Center for Health Statistics (NCHS) to examine the performance of the long form version of the American Association of Blood Banks (AABB) Uniform Blood Donor History Questionnaire (UBDHQ). (cdc.gov)
- At the time of tissue procurement, the donor said that he had had a 'cyst' removed from the left side of his neck in July 1984. (cdc.gov)
- none of the donor tissues were transplanted. (cdc.gov)
Allograft2
- TBI is a recognized innovator in the field of eye and tissue banking and has led advancements in recovery, processing, and distribution of allograft tissue. (mightycause.com)
- Allograft bone obtained from the hospital bone bank was used in the procedure. (cdc.gov)
Samples20
- The types of research projects using samples or data sourced from Ethical Tissue involve many areas of biomedical science. (sciencedaily.com)
- The MCW Tissue Bank is an institutional core that provides research services involving human samples to faculty investigators. (mcw.edu)
- The Bank is a CAP accredited biorepository, which ensures high quality samples, vetted protocols and procedures, and knowledgeable, well trained staff. (mcw.edu)
- This map gives an overview of all the samples which are available in the Specimen Tissue Bank. (spc.int)
- The CEDOR Tissue Bank stores samples of blood and other tissue for future research. (ccdhb.org.nz)
- After a study is done using these donated samples we usually send the results to people whose blood or tissue was used in that study. (ccdhb.org.nz)
- The Mesobank will offer 20 new mesothelioma cell lines for study and will accept tissue and blood samples from a collaborative group of doctors and scientists across the UK. (survivingmesothelioma.com)
- Consent to this program involves a one-time donation of blood and tissue samples discarded from a single pregnancy. (mcw.edu)
- Tissue Banking at MCW involves storing health information and blood or tissue samples in the MCW Tissue Bank for the purpose of medical research. (mcw.edu)
- They also observed that adipocytes (indicators of inflammation) in breast tissue were larger and less healthy in the Type 2 diabetes samples compared that of non-diabetes samples. (iu.edu)
- Biobanks collect biological samples, including but not limited to tissue and blood samples, and connected data in a pseudonymized manner. (tum.de)
- In order to elucidate these molecular alterations, one of the most important sources for research are tissue samples handled by a biobank. (tum.de)
- Only dissected brain samples and topographically oriented tissue blocks are stored. (semmelweis.hu)
- Studies that use samples from the Tissue Bank include those targeting the discovery of new species, a better understanding of rare plants, and exploration of evolutionary relationships across the Channel Islands. (sbbotanicgarden.org)
- To collect Tissue Bank samples, botanists remove young leaves from a plant that is being collected for the Clifton Smith Herbarium, and botanists place the leaves into small envelopes. (sbbotanicgarden.org)
- The Garden's Tissue Bank currently contains over 10,000 samples representing 120 plant families and 460 genera. (sbbotanicgarden.org)
- The Tissue Bank currently contains over 10,000 samples representing 120 plant families and 460 genera, reaching far beyond the Santa Barbara region. (sbbotanicgarden.org)
- Tissue samples may also be viewed in person at the Garden by appointment only. (sbbotanicgarden.org)
- The tissue samples are made available after signing a statement about scientific collaborations with the HBTB ( http://humanbraintissuebank-budapest.sote.hu/dokument/FormNo1.pdf ) and a declaration of the proper use of human samples strictly for research studies ( http://humanbraintissuebank-budapest.sote.hu/dokument/FormNo2.pdf ). (msdiscovery.org)
- Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)
Frozen1
- There, the tissues remained frozen at -20° Celsius to -70° Celsius in individual double- wrapping and plastic bags and were handled and tested separately to reduce the risk for cross- contamination. (cdc.gov)
Baby's3
- Join us and other expectant parents to discover why banking your baby's stem cells is an amazing way to plan for your family's future health. (familycfa.com)
- Looking to bank your baby's cord blood at an affordable price? (progenics.ca)
- Treating MS with stem cells found in umbilical cord blood is another reason families are banking their baby's cord blood and tissue. (mazecordblood.com)
Scar4
- Scar Tissue. (eastbankchiropractic.com)
- These are your body's attempts at healing a soft tissue injury that results in collagenous scar tissue. (eastbankchiropractic.com)
- Scar tissue occurs when collagen fibers form over a site of injury, trauma, or inflammation. (eastbankchiropractic.com)
- The firm strokes and pressure applied during a deep tissue massage help break up scar tissues and enhance circulation, leading to overall better health and vitality. (phildickercommercials.co.uk)
Biobank1
- The tissue bank, termed MTBIO, is member of the Joint Biobank Munich . (tum.de)
Organ3
- This immune reaction leads to rejection, the greatest problem in successful tissue and organ grafting. (britannica.com)
- Our staff of dedicated professionals work tirelessly to facilitate organ, eye, and tissue donation throughout our service area. (dcids.org)
- Had a transplant such as organ, tissue, or bone marrow? (cdc.gov)
Licence2
- Having gained a Human Tissue Authority Licence and ethical approval status, they have now become one of the first University groups in the UK to open as a licensed ethically approved research tissue bank. (sciencedaily.com)
- There is no requirement for such banks to hold a HTA licence. (hta.gov.uk)
Umbilical cord1
- ACOG committee opinion no. 771: umbilical cord blood banking. (medlineplus.gov)
Research23
- These programs then charge their customers (mainly medical instrument companies) for services associated with preparation of the cadaver tissue (e.g. transportation, refrigeration, and recovery) rather than charging money for the donated tissue itself, though it is not illegal to do so for non-transplant and or research organizations per the Uniform Anatomical Gift Act as it is for transplant and/or therapy. (wikipedia.org)
- This has been made possible through links with NHS Trusts, the NHS Blood and Transplant Tissue Services, transplant co-ordinators and other collaborators, who understand the importance of human tissue in biomedical research and are committed to supporting the activities of the University's research tissue bank. (sciencedaily.com)
- In 2007 the group running the bank decided to expand their activities in response to the ever-increasing demands for access to a wider range of human tissue for use in biomedical research. (sciencedaily.com)
- Leeds and Bradford Hospital Trusts, who currently provide tissue to the bank, work with patients and their families to provide information about the supply of tissue for research purposes and manage the consent procedures which underpin the bank's high ethical standards. (sciencedaily.com)
- Mrs Sandie Martin, Head of Ethical Tissue, said: "This new and improved facility makes us a leader amongst current sources for processing and supply of human tissue to all types of biomedical research groups. (sciencedaily.com)
- Ethical Tissue will be a tremendous research resource for Bradford and the research community at large. (sciencedaily.com)
- This means that although much storage of research material is exempt from HTA licensing, the requirement to be licensed is relevant to many collections of research material, including those considered to be tissue banks. (hta.gov.uk)
- The HTA and the HRA's Research Ethics Service (HRA RES) have agreed a position whereby NHS RECs can give generic ethical approval for a research tissue bank's arrangements for collection, storage and release of tissue, providing the tissue in the bank is stored on HTA-licensed premises. (hta.gov.uk)
- Such research tissue banks need to be licensed because at least some of the tissue being stored is not for specific projects holding REC approval. (hta.gov.uk)
- Applications for ethical review of research tissue banks are voluntary. (hta.gov.uk)
- When applying for REC review, applicants are advised by the HRA to request review by a REC 'flagged' to review research tissue banks (RTBs). (hta.gov.uk)
- Some research banks hold material which is not considered 'relevant material' under the Human Tissue Act 2004. (hta.gov.uk)
- Tissue that is taken from the living for diagnosis and subsequently stored in a diagnostic archive can be a valuable research resource. (hta.gov.uk)
- The HTA's position is that if a diagnostic archive releases tissue for research occasionally upon request, its status as a diagnostic archive is clear. (hta.gov.uk)
- In a hospital press release, Dr. Robert Rintoul, who will lead the new tissue bank said, "In research terms, mesothelioma has been a neglected cancer for far too long. (survivingmesothelioma.com)
- This year we launched our Brain Tumour Tissue Campaign , which aims to increase the number of people consenting to donate their resected brain tumour tissue to research. (brainstrust.org.uk)
- We'll keep working hard until 80% of patients are consenting for their tissue to be used in future research and advancements in treatment can thus be made. (brainstrust.org.uk)
- Ask about donating your brain tumour tissue for research. (brainstrust.org.uk)
- We would like to collect a blood sample, tissue, pleural fluid, ascites fluid, breast milk, hair and nail clippings and medical information to use for research. (iu.edu)
- Each year, more than 130,000 TBI tissues are used in transplant surgery, with thousands more utilized in research and medical education. (mightycause.com)
- In 2022, the Tissue Bank will participate in the Global Genome Biodiversity Network, fueling research within the Garden as well as collaborations with institutions worldwide. (sbbotanicgarden.org)
- New research suggests the stem cells found in cord blood can improve the immune system's ability to support the body, and regenerate damaged nervous system tissue. (mazecordblood.com)
- An informatics-driven tissue banking effort for mesothelioma-the mesothelioma virtual bank model to accelerate translational research: an update. (cdc.gov)
Brain1
- Note: The Human Brain Tissue Bank is a member of BrainNet Europe. (msdiscovery.org)
AATB3
- The American Association of Tissue Banks (AATB) is the most recognized accrediting body for American tissue banks. (wikipedia.org)
- Through its federal advocacy efforts, AATB provides a unified voice for the tissue banking industry on key issues impacting the profession. (aatb.org)
- Guidelines for AATB accredited establishments to use in conjunction with the Standards for Tissue Banking and the Standards for Non-Anatomical Donation. (aatb.org)
Tumour1
- The tissue bank has its foundations in a highly successful tumour bank based within the University's Institute of Cancer Therapeutics. (sciencedaily.com)
Vascular1
- Corneas, heart valves, and vascular tissue were not procured. (cdc.gov)
Biospecimens1
- Your information and biospecimens will be stored in a repository called IU Simon Cancer Center Tissue Bank. (iu.edu)
Ethical6
- The bank will operate under the name 'Ethical Tissue' on a not-for-profit basis and will provide access to a wide range of human tissue and tissue products such as viable cells, cell fractions and arrays. (sciencedaily.com)
- Gaining ethical approval status has given us increased opportunities to operate in the areas of tissue procurement, transport, processing and storage. (sciencedaily.com)
- We've put together a sound business plan, developed an excellent network of tissue suppliers and we've satisfied all the regulatory and ethical regulations associated with the sourcing, storage and distribution of human tissues. (sciencedaily.com)
- Open to individuals involved or interested in the banking of cells, organs, eyes, or tissues who support our objectives, policies, and ethical standards. (aatb.org)
- Subject to conditions, the bank's ethical approval extends to specific projects receiving non-identifiable tissue from the bank. (hta.gov.uk)
- The RECs are also a source of ethical advice to the bank on its arrangements for collecting, managing and distributing tissue. (hta.gov.uk)
Graft1
- The amniotic membrane is turned into a tissue graft and used as an open wound dressing, known as a biological bandage. (nsw.gov.au)
Pathology1
- The close interaction between the routine pathology lab and the tissue bank is key in this workflow. (tum.de)
Biorepository1
- The National Mesothelioma Virtual Bank (NMVB ) is a virtual biospecimen tissue biorepository that was developed in 2006 at the University of Pittsburgh in partnership with a network of sites in the mid-Atlantic region. (cdc.gov)
20221
- In October 2022, the headquarters team toured the Food Bank as part of a visit to the Fort Edward facility. (regionalfoodbank.net)
Blood and tissue1
- Specifically, cord blood, cord tissue, placental blood and tissue, and amniotic fluid have demonstrated intriguing therapeutic promise, causing storage services for these biomaterials to proliferate. (bioinformant.com)
Donation of blood1
- If you have given a donation of blood or other tissue and change your mind then you can get that sample back or have it destroyed as you wish. (ccdhb.org.nz)
Methods1
- These use a variety of methods that identify different soft tissue points sensitive to palpation for treatment. (eastbankchiropractic.com)
20181
- Coinciding with our tissue collections, the first was in New York in November 2017, and the second in Phoenix in March 2018. (iu.edu)
Musculoskeletal1
- The possibility to draw on the Musculoskeletal Tissue Bank allows us to be able to overcome also the most difficult cases where severe bone loss is present, by obtaining customised bone grafts created with the most advanced 3D technology. (ior.it)
Corneal1
- Medicare makes separate payments for the acquisition of corneal tissue for use in corneal transplant and glaucoma shunt procedures. (safetygraft.com)
Human tissue2
- The only accreditation program for tissue establishments, recognizing the highest commitment to the quality and safety of donated human tissue. (aatb.org)
- However, the Human Tissue Act 2004 clearly provides that the storage of tissue for a 'scheduled purpose' must be on licensed premises. (hta.gov.uk)
Donate3
- With household tissue products in high demand by food pantries, we knew that partnering with the Regional Food Bank of Northeastern New York to donate bathroom tissue, facial tissue, paper towel and napkins was a way we could make an immediate and positive impact. (regionalfoodbank.net)
- Amnion donation is a unique living donation program, whereby women having an elective caesarean section can agree to donate their foetal tissues including the amnion membrane, which would otherwise be discarded. (nsw.gov.au)
- You can also decide to bank or donate cord blood at the time of your delivery. (medlineplus.gov)
Aims1
- Soft tissue mobilization also aims to improve range of motion, decrease swelling and edema, reduce pain, and restore or optimize muscle function. (eastbankchiropractic.com)
Cord blood banks8
- Substantial cord blood industry consolidation has happened in recent years and investor appetite for cord blood banks has never been stronger. (bioinformant.com)
- This is because cord blood banks produce stable subscription revenue from long-term storage contracts. (bioinformant.com)
- At a fundamental level, cord blood banks are both a real estate investment (cryogenic storage facilities) and a regenerative medicine (RM) play. (bioinformant.com)
- In addition to an aggressive M&A environment, a growing number of cord blood banks have been venturing into new types of stem cell storage, reproductive services, and related cell therapy applications. (bioinformant.com)
- What are the strategies being considered to improve the financial stability of public cord blood banks? (bioinformant.com)
- Why do most public cord blood banks incur a loss? (bioinformant.com)
- What are the prices for processing and storage of cord blood in private cord blood banks? (bioinformant.com)
- Cord blood banking for personal use is done by both cord blood banks and private companies. (medlineplus.gov)
Tendons1
- A powerful and efficient therapy, deep tissue massage that targets the inner layers of muscles, tendons, and fascia for addressing muscle tension, lowering stress, and enhancing well-being. (phildickercommercials.co.uk)
Relieve1
- The soothing ambience and intentional pressure applied during a deep tissue massage can relieve stress and anxiety by inducing the release of endorphins and a relaxation response. (phildickercommercials.co.uk)
Patients1
- The Bank offers three robust consent programs to patients of Froedtert Hospitals and clinics, that include the General Tissue Bank, the Maternal Bank, and the COVID-19 Bank. (mcw.edu)
Biomedical1
- A tissue bank may also refer to a location where biomedical tissue is stored under cryogenic conditions and is generally used in a more clinical sense. (wikipedia.org)
AABB1
- PROGENICS IS THE ONLY CANADIAN STEM CELL BANK WITH ACCREDITATIONS FROM FACT AND AABB, AND IS REGISTERED WITH HEALTH CANADA AND THE FDA. (progenics.ca)
Nonprofit2
- The Rocky Mountain Lions Eye Bank was founded as a nonprofit in 1982 by the Lions of Colorado and Wyoming. (corneas.org)
- For more than 45 years, the nonprofit South Texas Blood & Tissue Center has focused on a critical purpose: to save and improve lives. (biobridgeglobal.org)
Distribution2
- Student volunteers depackage and box Irving Tissue paper towel donations for distribution to our agency partners. (regionalfoodbank.net)
- It facilitates the retrieval, storage, preparation and distribution of tissue in NSW and the ACT. (nsw.gov.au)
Gaining1
- Gaining insight into the technique is essential for fully experiencing deep tissue massage benefits , which sets it apart from other massage types. (phildickercommercials.co.uk)
Muscle2
- Working within the deeper layers of muscle tissue is the main objective of deep tissue massage to address muscle knots, adhesions, and tension. (phildickercommercials.co.uk)
- By working on muscle tension due to improper posture, alignment can be improved and the risk of future problems reduced through deep tissue massage. (phildickercommercials.co.uk)
Health5
- Our tissue bank is approved by the Health and Disability Ethics Committee and is governed by a group of DHB staff. (ccdhb.org.nz)
- If you are a clinician interested in ordering amnion grafts, please contact the NSW Tissue Bank at [email protected] or call 02 9382 7288 . (nsw.gov.au)
- We do our best to share the latest news and updates on cord blood and cord tissue banking as well as pregnancy, childbirth, and pediatric health. (mazecordblood.com)
- As part of the Maze Health group, Maze Cord Blood Labs represents the founder's commitment to family and affordability, making Cord Blood Banking available to as many families as possible. (mazecordblood.com)
- If you choose to bank your infant's cord blood, you should talk to your health care provider about the pros and cons of different options. (medlineplus.gov)