Time Factors: Elements of limited time intervals, contributing to particular results or situations.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.History, 20th Century: Time period from 1901 through 2000 of the common era.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Ice Cover: A thick mass of ICE formed over large regions of land; RIVERS; LAKES; ponds; or SEAWATER.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.History, 21st Century: Time period from 2001 through 2100 of the common era.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.History, 19th Century: Time period from 1801 through 1900 of the common era.United StatesPrevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Terminal Care: Medical and nursing care of patients in the terminal stage of an illness.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Geography: The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.History, Ancient: The period of history before 500 of the common era.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Infant, Newborn: An infant during the first month after birth.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.History, 18th Century: Time period from 1701 through 1800 of the common era.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.EuropeClimate: The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Genetic Variation: Genotypic differences observed among individuals in a population.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Phylogeography: A field of study concerned with the principles and processes governing the geographic distributions of genealogical lineages, especially those within and among closely related species. (Avise, J.C., Phylogeography: The History and Formation of Species. Harvard University Press, 2000)Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.BrazilFossils: Remains, impressions, or traces of animals or plants of past geological times which have been preserved in the earth's crust.ItalyDose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.History, 17th Century: Time period from 1601 through 1700 of the common era.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.History, 16th Century: Time period from 1501 through 1600 of the common era.Terminally Ill: Persons with an incurable or irreversible illness at the end stage that will result in death within a short time. (From O'Leary et al., Lexikon: Dictionary of Health Care Terms, Organizations, and Acronyms for the Era of Reform, 1994, p780)Sexual Behavior: Sexual activities of humans.Spain: Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)DNA, Mitochondrial: Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Paleontology: The study of early forms of life through fossil remains.France: A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.Kinetics: The rate dynamics in chemical or physical systems.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.IndiaCattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Gestational Age: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.HIV Infections: Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Palliative Care: Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.History, Medieval: The period of history from the year 500 through 1450 of the common era.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.History, 15th Century: Time period from 1401 through 1500 of the common era.Condoms: A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Hominidae: Family of the suborder HAPLORHINI (Anthropoidea) comprising bipedal primate MAMMALS. It includes modern man (HOMO SAPIENS) and the great apes: gorillas (GORILLA GORILLA), chimpanzees (PAN PANISCUS and PAN TROGLODYTES), and orangutans (PONGO PYGMAEUS).Anthropology, Physical: The comparative science dealing with the physical characteristics of humans as related to their origin, evolution, and development in the total environment.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Pregnancy, Animal: The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.Time: The dimension of the physical universe which, at a given place, orders the sequence of events. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Population Dynamics: The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Age Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Great BritainRecombinant Proteins: Proteins prepared by recombinant DNA technology.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Oceans and Seas: A great expanse of continuous bodies of salt water which together cover more than 70 percent of the earth's surface. Seas may be partially or entirely enclosed by land, and are smaller than the five oceans (Atlantic, Pacific, Indian, Arctic, and Antarctic).Health Knowledge, Attitudes, Practice: Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Bacterial Proteins: Proteins found in any species of bacterium.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Parity: The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)SwedenDiet: Regular course of eating and drinking adopted by a person or animal.Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.Climate Change: Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Genetics, Population: The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES.NorwayRadiometric Dating: Techniques used to determine the age of materials, based on the content and half-lives of the RADIOACTIVE ISOTOPES they contain.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Risk-Taking: Undertaking a task involving a challenge for achievement or a desirable goal in which there is a lack of certainty or a fear of failure. It may also include the exhibiting of certain behaviors whose outcomes may present a risk to the individual or to those associated with him or her.Archaeology: The scientific study of past societies through artifacts, fossils, etc.Disease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.Sexual Partners: Married or single individuals who share sexual relations.Population Surveillance: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Siberia: A region, north-central Asia, largely in Russia. It extends from the Ural Mountains to the Pacific Ocean and from the Arctic Ocean to central Kazakhstan and the borders of China and Mongolia.Data Collection: Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.GermanyDemography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Exons: The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or other functional RNA.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.China: A country spanning from central Asia to the Pacific Ocean.Cold Climate: A climate characterized by COLD TEMPERATURE for a majority of the time during the year.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.South AmericaAsia: The largest of the continents. It was known to the Romans more specifically as what we know today as Asia Minor. The name comes from at least two possible sources: from the Assyrian asu (to rise) or from the Sanskrit usa (dawn), both with reference to its being the land of the rising sun, i.e., eastern as opposed to Europe, to the west. (From Webster's New Geographical Dictionary, 1988, p82 & Room, Brewer's Dictionary of Names, 1992, p34)Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Hospice Care: Specialized health care, supportive in nature, provided to a dying person. A holistic approach is often taken, providing patients and their families with legal, financial, emotional, or spiritual counseling in addition to meeting patients' immediate physical needs. Care may be provided in the home, in the hospital, in specialized facilities (HOSPICES), or in specially designated areas of long-term care facilities. The concept also includes bereavement care for the family. (From Dictionary of Health Services Management, 2d ed)Introns: Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.Atmosphere: The gaseous envelope surrounding a planet or similar body. (From Random House Unabridged Dictionary, 2d ed)Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.SwitzerlandRegistries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.AfricaEmigration and Immigration: The process of leaving one's country to establish residence in a foreign country.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)IsraelWater Movements: The flow of water in enviromental bodies of water such as rivers, oceans, water supplies, aquariums, etc. It includes currents, tides, and waves.Conservation of Natural Resources: The protection, preservation, restoration, and rational use of all resources in the total environment.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Extinction, Biological: The ceasing of existence of a species or taxonomic groups of organisms.PolandComputer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Fetus: The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.Haplotypes: The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.North AmericaPain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Breast Neoplasms: Tumors or cancer of the human BREAST.Trees: Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.Multigene Family: A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)Sequence Deletion: Deletion of sequences of nucleic acids from the genetic material of an individual.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Global Warming: Increase in the temperature of the atmosphere near the Earth's surface and in the troposphere, which can contribute to changes in global climate patterns.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Organ Size: The measurement of an organ in volume, mass, or heaviness.Hospitalization: The confinement of a patient in a hospital.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Rural Population: The inhabitants of rural areas or of small towns classified as rural.Atlantic Ocean
As The New York Times wrote, "At age 21, Mr. Leonard walked away from rock fame to pursue his real love: linguistics. Turns out ... Leonard was rated by TIME magazine as the second smartest rock star in history: "[He] opened for Jimi Hendrix [at Woodstock]… ... Finn, Robin (June 15, 2008). "A Graduate of Sha Na Na, Now a Linguistics Professor". The New York Times. "In Memoriam: William ... Kim, Wook (September 6, 2012). "School of Rock: 10 Supersmart Musicians". Time. Tabios, Eileen (September 10, 1979). "Sha Na ...
Businessweek profile International Herald Tribune profile New York Times profile (paid) Asia Times profile Time magazine ... At the same time, a petrol bomb was thrown at the Next Media headquarters in Tseung Kwan O Industrial Estate. The fires were ... The following day, Lai announced he would step down as head of Next Media "so as to spend more time with his family and further ... It was at this time he converted to the Catholic faith, which has a long history in China. Lai pioneered a reader-centric ...
"Religion: Small War in Sweden". TIME. October 21, 1957. ...
Tine Rømer Holtegaard was asleep, having taken sleeping pills, when she was stabbed at least 20 times in the chest. Borch, who ... Spear, Lisa (16 September 2015). "ISIS-Inspired Teen Lisa Borch Jailed Over Mom's Stabbing Death". TIME. Retrieved 20 September ... Charter, David (16 September 2015). "Teen kills mother after viewing Isis beheadings". The Times. Retrieved 20 September 2015 ...
Pendergrass, Eugene P. (Autumn 1965). "Review of The Life and Times of Emil H. Grubbe by Paul C. Hodges". Isis. 56 (3): 395. ... Hodges, Paul C. (1964). The Life and Times of Emil H. Grubbe. University of Chicago Press. Mukherjee, Siddhartha (16 November ...
"Val Bjornson". The New York Times. March 12, 1987. Retrieved May 27, 2010. CQ Weekly Report, Volume 12, page 1040. ... Congressional Quarterly, 1954 http://www.icelandminnesota.com/scholarship.htm "National Affairs: Who Won". Time. September 27, ...
Over time, however, her pay slipped in comparison to the pay of male area managers with equal or less seniority. By the end of ... Grace and Grit is the first time she shared her life story and journey leading to her national struggle for fair pay. On ... The act seeks to reverse the Supreme Court's ruling in Ledbetter v. Goodyear, which restricted the time period for filing pay ... Under this bill, every discriminatory paycheck or other compensation can be filed, unrestricted from a time period for filing a ...
"Sport: Who Won". Time. 30 June 1952. Retrieved 10 February 2012. ...
13, 1950 -- Page 1". Time. November 13, 1950. Retrieved 2007-01-13. "Gathering Leaves - A Family History Encyclopedia - Person ...
Dubbed "the three-time loss from Holy Cross" by detractors, Casey hired two then-generally unknown political strategists, James ... He also refused to say whether he would campaign for the Democratic nominee, though he told the New York Times, "I support the ... Wines, Michael (August 1, 1996). "The States And The Issues". The New York Times. Retrieved May 22, 2010. Casey, Robert P. ( ... Newton-Small, Jay (November 24, 2009). "Can a Pro-Life Dem Bridge the Health-Care Divide?". Time. Retrieved December 6, 2010. ...
The New York Times. 12 December 1986. "The press: samizdat West". Time. 105 (15). 14 April 1975. Alexeyeva, Lyudmila; ... During this time he had met several fellow dissidents, including Larisa Bogoraz, the wife of his associate Yuli Daniel, who ... During his time in the camps Marchenko educated himself, reading a number of accessible socio-political works, including the ... My Testimony provided a detailed account of both his time in labour camps and in prison, as well as a wide-ranging look at ...
In 1905, the Hartford City Times and Blackford County Gazette were merged, and the new weekly became known as the Times-Gazette ... Beginning 2007, the Hartford City News-Times began using the name News-Times on its web site (without Hartford City), and calls ... See "Talking Pictures Seen Here Tonight for First Time" in the August 3, 1908 edition of Hartford City's Times-Gazette. Gray's ... and the combined entity became the Hartford City News-Times. The Hartford City News-Times, changing ownership over the years, ...
A 29 December 1975 TIME cover story named her as one of the world's "living saints" in a list that included Mother Teresa, ... TIME. 106: 447. 1975. Calian, Carnegie Samuel (1982). Today's Pastor in Tomorrow's World. Westminster Press. p. 51. ISBN ...
"Died". Time. 17 June 1985. Retrieved 2008-07-20. John Ringling North, 81, flamboyant, fast-talking showman who from 1937 to '43 ... Petersburg Times. September 28, 1947. Retrieved 2009-02-12. Miss Mabel Ringling. 23, granddaughter of a founder of the Ringling ... Head of Tented Shows In America Dies in New Orleans" (PDF). New York Times. August 19, 1907. Retrieved 2008-07-20. When the ... One of Six Famous Brothers". New York Times. Retrieved 2008-07-21. One of the famous "six brothers of Baraboo," Charles ...
In a road network, congestion can be considered a specific measure of the time delay in a journey or time lost through traffic ... Daniel Gross (2007-02-17). "What's the Toll? It Depends on the Time of Day". The New York Times. Retrieved 2008-07-15. Victoria ... For example, in the case of a Boeing 757, the peak landing fee was about 2.5 times higher than the off-peak fee in all three ... During weekends cars pay US$5. The toll remained at the previous toll of US$4 at all other times on weekdays. According to the ...
Ozersky, Josh (June 8, 2010). "In Medium Raw, Bourdain Is the Last Honest Man". TIME. GQ Contributors Page The Craft of Food ... "WEDDINGS; Lettie Teague, Alan Richman". The New York Times, October 2, 1994. October 2, 1994. Archived from the original on 29 ... Faerie Folk' Strike Back With Fritters". New York Times, Kim Severson, December 6, 2006. December 6, 2006. Retrieved April 23, ...
Her 1963 times of 51.4 (400 m) and 1:59.1 (800 m) bettered the world records, the latter the first woman under 2 minutes. They ... Ann Packer won the Olympic 800 m in a new official world record of 2.01.1. In 1966, Time magazine stated in an article on the ... In October 1960, she surpassed the 400 metres world record with an unratified time of 53.0. She won the 400 m at the Brothers ... A note in the 1964 British Athletics yearbook states, "The IAAF are withholding recognition of a time of 53.1 by Betty Cuthbert ...
Rule, Sheila (February 20, 1992). "On a D Train in Disguise, the Grammys Ride In". The New York Times. The New York Times ... Strauss, Neil (February 27, 2002). "The Pop Life; Tough Competition At Grammys". The New York Times. The New York Times Company ... Shazli, Ardi (February 5, 1996). "Limited tickets to see Grammy awards in LA". New Straits Times. New Straits Times Press. ... permanent dead link] Lewis, Martin (February 21, 2001). "The Pre-Grammys: Song-By-Song-By-Simon". Time. Time Inc. Retrieved ...
At the same time, Democrat Bill Clinton carried Louisiana by a considerable margin of 927,837 votes to 712,586 cast for ... Time. Retrieved June 4, 2008. Elections Division from the Louisiana Secretary of State. ...
Her husband was questioned by a judge but has not been charged at this time. Prosecutors believe he may have been unaware of ... Time. Paris. Retrieved 21 April 2017. "Details emerge in French baby killing case". BBC News. 29 July 2010. Retrieved 21 April ...
"A New Coal Pact," Time, June 8, 1981; Hartson, "Sam Church Faces His Greatest Challenge," Gettysburg Times, March 30, 1981; " ... New York Times, September 28, 1982; "Mine Union Chiefs Sue Over Campaign Tactics," New York Times, March 5, 1983. Robbins, " ... By this time, his political opponents had decided that his erratic behavior and poor physical condition justified putting him ... "Surprise Strike." Time. April 13, 1981. Wysong, Jere A. and Williams, Sherman R. "The UMWA Health Care Program for Miners: ...
In a later interview to TIME magazine, the lead air marshal aboard the flight stated, "there was never a time when my main ... A Washington Times story claimed that some air marshals believed that Northwest flight 327 was a "dry run" for a future ... One such passenger confirmed the story to the Washington Times. Debate over what happened on the flight became an Internet ... Donnelly, Sally B. (August 4, 2004). "An Air Marshal's View of Flight 327". Time. Retrieved August 11, 2006. "Terror in the ...
Brian spent time in the Menard Correctional Center from 1979 until 1982. On February 25, 1983, 10-year-old Jeanine Nicarico ( ... Gacy prosecutor Terry Sullivan doubted the story, pointing out that not only did Dugan not come forward at the time of the ... Cohen, Adam (1999-03-21). "The Frame Game". Time. Retrieved 2011-03-13. Gutowski, Christy (2009-10-05). "Cruz: Dugan Confessed ...
At this time Volks was a producer of resin figure kits, and the early Super Dollfie were made and sold similarly to resin kits ... The first release was a limited run of only 50 dolls, but sales were so successful that the doll was rereleased two times, and ... Yo-SD, from the Japanese infant (幼, yō), are only available as limited editions, but they have been released several times. ... Ball-jointed doll Dollfie Time Magazine, AVERY HOLTON, "Anime Girls", Sunday, Jul. 18, 2004 "a tough polyurethane-resin mix ...
Begley, Sarah (25 January 2017). "Review: Paul Auster's New Novel Is Four Times the Fun". Time. Retrieved 20 November 2017. ... At the time of its publication, it was the first new Auster novel to have appeared in seven years. Auster worked on the book ... At the time of its publication in January and February 2017, the book received mixed reviews, and with widely divergent ... The novel is the story of Archie Ferguson told at four different times, and in four different versions. Each chapter in the ...
Argento at the time.. Ms. Argento, who lives in Rome, subsequently turned to Ms. Goldberg - a prominent lawyer for victims of ... The Times has tried repeatedly since Thursday to get a response to the matter from Ms. Argento and her representatives. She did ... The documents, which were sent to The New York Times through encrypted email by an unidentified party, include a selfie dated ... Carrie Goldberg, her lawyer who handled the matter, read email messages from The Times, according to two people familiar with ...
The New York Times: Find breaking news, multimedia, reviews & opinion on Washington, business, sports, movies, travel, books, ... The New York Times gathered names of the dead and memories of their lives from obituaries across the country, helping to reckon ...
Japan should enforce a law parallel to the US Taiwan Relations Act (TRA) to consolidate its partnership with Taiwan, Jikido Aeba, a Japanese lawmaker and academic, told a seminar in Taipei yesterday. He is also concerned about Taiwans security in the face of mounting Chinese pressure, ...FULL STORY ...
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Forest River is recalling model year 2017-2018 Prime Time Wildcat fifth-wheel recreational trailers as carbon monoxide may ... Forest River recalls Prime Time Wildcat fifth-wheel recreational trailers. Carbon monoxide may enter the vehicle. 09/26/2017 , ... Forest River is recalling 88 model year 2017-2018 Prime Time Wildcat fifth-wheel recreational trailers. ...
Time matters. When sepsis is quickly recognized and treated, lives are saved. Healthcare providers are the critical link to ...
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It doesnt mean that Chinas economy is three or four times better, or its model is somehow desirable. Rather,... ... Observers dont get very excited about the fact that Chinas economic growth is frequently three or four times what America ... Real Time Economics. Rortybomb. Ryan Avent. Spencer Ackerman. The Stash. Steve Benen. Tapped. Taxvox. Tom Laskawy. The ... It doesnt mean that Chinas economy is three or four times better, or its model is somehow desirable. Rather, its in large ...
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A mood disorder developed at some time during the first year after injury in 46 of 92 patients with a TBI (51%), compared with ... Furthermore, these changes may persist and evolve with time.. A significant proportion of patients in whom mood disorders ... Among study participants without a history of psychiatric illness, those with moderate to severe TBI were 4 times (95% ...
Youll get full access to our website, print and digital editions, and the Times Higher Education app for iOS, Android and ... If you like what youre reading online, why not take advantage of our subscription and get unlimited access to all of Times ... This UK university league table reveals the 93 best UK universities and colleges, according to the trusted Times Higher ...
Live From Upswell: Now Is Time To Step Up. Paul Clolery November 15, 2018. LOS ANGELES - The "brutal fact" in the nation and ... The NonProfit Times November 15, 2018. It has been six months since the General Data Protection Regulation (GDPR) went onto ... Live From Upswell: Now Is Time To Step Up. Paul Clolery November 15, 2018. ...
Sample interpretation: Compared with 5-17-year-olds, the rate of death is 45 times higher in 30-39-year-olds and 7,900 times ... Compared with 18-29-year-olds, the rate of hospitalization is 8 times higher in 75-84-year-olds (55 divided by 7 equals 7.9). ...
Recovery Time. Muscles need 48 hours for baseline strength to recover from high-intensity strength training. This finding is ... The primary programming factors for you to consider are length of recovery time after strength training, and the frequency, ... perform cardiovascular and strength training in the same session because it seems to achieve multiple goals at the same time. ...
A Method for Measuring Similarity of Simulation Time-Series Data Based on Dynamic Time Warping. Ping Ma, Zhong Zhang, Kaibin ... How Real-time Analysis Turns Big Medical Data Into Precision Medicine?. Dr.-Ing. Matthieu-P. Schapranow, Hasso Plattner ... A Real-time Color-matching Method Based on SmartPhones For Color-blind People. MyoungBeom Chung, Hyunseung Choo ... Early Detection of Critical Faults Using Time-Series Analysis on Heterogeneous Information Systems in the Automotive Industry. ...
Im tired all the time, should I try a detox diet?. *The low-down on Paleo - Welcome to our three part series on the ... Im tired all the time, should I try a detox diet?. *The low-down on Paleo - Welcome to our three part series on the ... Time spent on home food preparation and indicators of healthy eating. Am J Prev Med. Published online 18 Sept, 2014. ... Regular exercise goes hand-in-hand with healthy eating, and making time to exercise is protective for our health in the long ...
Her pain was gone in a few months.CreditIan C. Bates for The New York Times. By. Gina Kolata ... View all New York Times newsletters.. An error has occurred. Please try again later.. You are already subscribed to this email. ... Sign up for Science Times. Well bring you stories that capture the wonders of the human body, nature and the cosmos. ... You agree to receive occasional updates and special offers for The New York Times products and services. ...
He ran 10 miles a day as the legend goes, and I too I love to run; all the time, at random times -never planned or strategized ... Eating back in paleolithic time were much more seasonal, so certain nutrients were not around in certain times of the year, ... But the question is, have we had time to adapt sufficiently to make it a healthy food? I would argue the answer is no. There ... As a first-time reader of your blog, its refreshing to see some rationality in the Paleo debate.. Its also interesting to see ...
Online Support 24/7. Zithromax 1 Time Dose. Discreet Packaging Via Recorded Delivery. ... It seems that online illnesses come to zithromax 1 time dose restrictive insufficiencies about folic times. If you do choose to ... Is quickly determined bad history which the zithromax 1 time dose the is ibufem anything prolonged therapy timing correctly ... Zyloprim performs adenomyomas of zithromax 1 time dose town prescriptions with different capsules of time. Since this increased ...
... it will ensure that a taxpayers existing tax debt will not grow through interest charges during this difficult time. ...
Enter Joda-Time, an easy-to-use open source date/time library for the Java platform. As youll see in this article, Joda-Time ... Applications need to know what time it is and what time its going to be, and sometimes they must calculate the path between ... eases the pain and tedium of manipulating dates and time. ... But at the time of this writing, the Joda-Time API appears to ... And a Joda-Time implementation for Google Web Toolkit (called Goda-Time) has also seen some progress but at the time of this ...
PC Clock Difference Exploring Time from Planck Time to the lifespan of the universe Different systems of measuring time Time on ... of time to an earthbound observer. In this view, all points in time (including future times) "persist" in some way. Time travel ... mean time; apparent time; Greenwich Time. 4. a limited period or interval, as between two successive events: a long time.... 14 ... Time is what clocks measure. We use time to place events in sequence one after the other, and we use time to compare how long ...
Its time again for the GNOMEYs, where we celebrate the best and worst of Cereal Time.. This is our last video for a while as ... Final Show! Cereal Time Awards 2016 , Cereal Time - Duration: 11 minutes.. *2 years ago ... Watch Cereal Time every weekday morning from 6am UK time.. Want to help m... ... We Act Out Harry Potter & The Cursed Child #NoSpoilers , Cereal Time - Duration: 10 minutes.. Cereal Time ...
Were launching our Trusts Time Capsule Competition today! In this competition we are challenging our children to work on ... Push the limits with a new piece of technology - Imagine what you might be using in 10 Years time? ... And of course, this is also an invitation to create their very own Time Capsule! ... their own, in pairs or a group of three to develop or represent five things for their time capsule, (to be opened in 10 years ...
  • Standard time zones of the world since 2016. (wikipedia.org)
  • Time for School: 2003 - 2016 puts a human face on an underreported global crisis, by spotlighting the 12-year journey of five extraordinary children in five countries as they struggle to get a basic education. (pbs.org)
  • We're launching our Trust's Time Capsule Competition today! (google.com)
  • In this competition we are challenging our children to work on their own, in pairs or a group of three to develop or represent five things for their time capsule, (to be opened in 10 years - if you wish to do that! (google.com)
  • And of course, this is also an invitation to create their very own Time Capsule! (google.com)
  • Back up a lifetime's worth of memories with AirPort Time Capsule, a wireless hard drive that works seamlessly with Time Machine in OS X. It's also a full-featured Wi-Fi base station with the latest 802.11ac technology and simultaneous dual-band support. (apple.com)
  • AirPort Time Capsule includes a 2TB or 3TB hard drive that works with Time Machine in OS X to create the perfect no-hassle backup solution. (apple.com)
  • With 802.11ac technology and a powerful beamforming antenna array, AirPort Time Capsule gives you up to 3x faster Wi-Fi and a stronger, clearer signal. (apple.com)
  • With the antennas at the top of the elevated design, AirPort Time Capsule now has a higher platform for dispersing the signal. (apple.com)
  • Connect your DSL or cable modem to AirPort Time Capsule and use the built-in setup assistant to create your new wireless network in just a few taps from your iPhone, iPad, or iPod touch. (apple.com)
  • AirPort Time Capsule can turn any external USB hard drive into a secure drive you can share across your Wi-Fi network. (apple.com)
  • Any Wi-Fi device you have will work with AirPort Time Capsule. (apple.com)
  • And since AirPort Time Capsule features a built-in firewall that protects your network from malicious Internet attacks, you can enjoy the web with peace of mind. (apple.com)
  • Could you please tell me what the 'time capsule' means in the following context? (usingenglish.com)
  • A 'time capsule' is usually a box that is sealed and often buried containing items typical of the time, like newspapers, magazines or anything else that is suggested as representing life at that time. (usingenglish.com)
  • I understand the original meaning of 'time capsule' (I actually made it when I was younger), but I suppose this is used as a different meaning in that context. (usingenglish.com)
  • what goes into a time-capsule are usually everyday items which nevertheless are iconic of the age. (usingenglish.com)
  • To say his 'stupid remark' is going into a time-capsule suggests that it is the epitome of all stupid remarks ever to be made. (usingenglish.com)
  • In my language we would not use 'time capsule' to express such a meaning. (usingenglish.com)
  • A milestone birthday, a college party house, and an eighteen-year-old time capsule. (newyorker.com)
  • Everybody had turned forty or was about to, so, even though the time capsule had been in the ground for only eighteen years, not a significant number, we decided to dig it up. (newyorker.com)
  • Then, at once, before you knew it, the time for the Time-Capsule Party had arrived-a last hurrah. (newyorker.com)
  • An operational definition of time, wherein one says that observing a certain number of repetitions of one or another standard cyclical event (such as the passage of a free-swinging pendulum) constitutes one standard unit such as the second, is highly useful in the conduct of both advanced experiments and everyday affairs of life. (wikipedia.org)
  • Generally speaking, methods of temporal measurement, or chronometry, take two distinct forms: the calendar, a mathematical tool for organising intervals of time, and the clock, a physical mechanism that counts the passage of time. (wikipedia.org)
  • Others, however, will note the impressive duration of the trilobites' passage through geologic time, as well as their incredible diversity, which saw over 25,000 scientifically recognized species end up inhabiting every available oceanic niche within their world. (amnh.org)
  • From birth to death, through the passage of time with the rising and setting of the sun, man appears young or old, on earth, in the stars or beyond, whether in heaven or hell. (louvre.fr)
  • The second section, 'Time Exposed,' examines photographers whose work gives form to the literal passage of time as well as moments of historic and cultural change. (nga.gov)
  • The irreversibility and inexorability of the passage of time is borne in on human beings by the fact of death . (britannica.com)
  • That method takes as an argument the number of milliseconds since January 1, 1970 at midnight Greenwich Mean Time (GMT) (also known as the epoch ), correcting for time zone. (ibm.com)
  • Unfortunately, it appeared to contain one too many missiles, a point that had not emerged before the photo was used on the front pages of The Los Angeles Times, The Financial Times, The Chicago Tribune and several other newspapers as well as on BBC News, MSNBC, Yahoo! (youtube.com)
  • performance for auditoriums is the reverberation time, which is directly proportional to the volume of the hall and inversely proportional to the amount of sound absorbency within it, including wall and ceiling surfaces and the audience itself. (britannica.com)
  • Amount of RNA required for Real Time Arrays is directly proportional to the number of assay plates being analyzed. (utmb.edu)
  • https://www.geosociety.org/documents/gsa/timescale/timescl.pdf displays the current Geologic Time Scale, which serves as a reference for study of the trilobites on this website. (amnh.org)
  • An Iranian government scientist claims to have invented a real, working time machine--the latest in a list of wild inventions from the country with no basis in reality. (youtube.com)
  • All clocks within each zone would be set to the same time as the others, but differed by one hour from those in the neighboring zones. (wikipedia.org)
  • With remarkable precision, the arrival-time clocks tell you to the minute when the next trains are due. (yahoo.com)
  • When the New Year arrived, so did an app that provides real-time arrival information that's synced to underground clocks at about a third of the subway stops. (yahoo.com)
  • As explained in the featured video, daylight saving time is intended to give you more access to daylight hours, thereby reducing energy costs and promoting healthy outdoor activities, and for nearly a century countries around the world have moved their clocks forwards in the spring and backward in the fall. (lewrockwell.com)
  • The risk decreased again after clocks were reset back to standard time in the fall. (lewrockwell.com)
  • Using Esri's solutions, response teams were able to stay connected with each other and share secure information with other first responders for real-time, shared situational awareness. (esri.com)
  • Get a step-by-step blueprint to leveraging precision medicine and genomics to capture market share in these turbulent times. (intel.com)
  • Technology enables physicians to share and monitor data instantly across multiple devices, saving time and improving care. (intel.com)
  • A study, published in 2007… combined surveys from 55,000 people in central Europe with data on 50 individuals' sleeping and wakefulness patterns for eight weeks around the shifts to and from daylight saving time. (lewrockwell.com)
  • The researchers found people never fully adjust their circadian rhythms to the hour shift associated with daylight saving time (or, as it is known in Europe, summer time). (lewrockwell.com)
  • According to Till Roenneberg, a German chronobiologist, your circadian body clock (which is set by daylight and nighttime darkness) never adjusts to the gaining of an "extra" hour of sunlight at the end of the day during daylight saving time. (lewrockwell.com)
  • This second view, in the tradition of Gottfried Leibniz and Immanuel Kant, holds that time is neither an event nor a thing, and thus is not itself measurable nor can it be travelled. (wikipedia.org)
  • The primary programming factors for you to consider are length of recovery time after strength training, and the frequency, type, intensity and volume of endurance training. (acefitness.org)
  • Currently, the international unit of time, the second, is defined by measuring the electronic transition frequency of caesium atoms (see below). (wikipedia.org)
  • Because Universal Time is synchronous with night and day, and more precise atomic-frequency standards drift away from this, however, UT is still used to produce a correction (called a leap second ) to atomic time, in order to obtain a broadcast form of civil time that carries atomic frequency. (wikipedia.org)
  • Thus, civil broadcast standards for time and frequency usually follow International Atomic Time closely, but occasionally step (or "leap") in order to prevent them from drifting too far from mean solar time. (wikipedia.org)
  • The Fourier transform relates the function in the time domain, shown in red, to the function in the frequency domain, shown in blue. (wikipedia.org)
  • A time-domain graph shows how a signal changes with time, whereas a frequency-domain graph shows how much of the signal lies within each given frequency band over a range of frequencies. (wikipedia.org)
  • The use of the contrasting terms time domain and frequency domain developed in U.S. communication engineering in the late 1940s, with the terms appearing together without definition by 1950. (wikipedia.org)
  • The Frame Timing API enables web developers to monitor the performance of their applications, as experienced by their users, by observing when the browser is unable to deliver the desired refresh rate due to long-running frames that exceed the allotted time budget. (w3.org)
  • As part of an integrated solution for emergency management operations, Esri provides a capability that enables real-time situational awareness for responders. (esri.com)
  • Einstein was describing one of the most profound implications of his Theory of General Relativity - that the perception of time is subjective. (scienceblogs.com)
  • Perception of odor intensity and time-course of olfactory adaptation. (springer.com)
  • By embracing this complexity, contemporary artists have placed photography at the center of a renewed discussion around the construction of history and memory and the perception of time. (nga.gov)
  • The New York Times gathered names of the dead and memories of their lives from obituaries across the country, helping to reckon with the devastation. (nytimes.com)
  • Artifacts from the Paleolithic suggest that the moon was used to reckon time as early as 6,000 years ago. (wikipedia.org)
  • They both sound OK, yet I reckon that the correct one is it's high time we left because it refers to a present that is entirely possible, yet not happening, thus the subjunctive. (usingenglish.com)
  • Nowadays, UT in relation to International Atomic Time (TAI) is determined by Very Long Baseline Interferometry (VLBI) observations of distant quasars, a method which can determine UT1 to within 4 milliseconds. (wikipedia.org)
  • Author, The Trouble With Physics THE LIBERATION OF TIME I would like to describe a change in viewpoint, which I believe will alter how we think about everything from the most abstract questions on the nature of truth to the most concrete questions in our daily lives. (mail-archive.com)
  • The problem of time confronts us at every key juncture in fundamental physics: What was the big bang and could something have come before it? (mail-archive.com)
  • Another manifestation of this ancient view is the currently popular idea that time is an emergent quality not present in the fundamental formulation of physics. (mail-archive.com)
  • Time is a component quantity of various measurements used to sequence events, to compare the duration of events or the intervals between them, and to quantify rates of change of quantities in material reality or in the conscious experience. (wikipedia.org)
  • The Future of Cereal Time - Duration: 16 minutes. (youtube.com)
  • How Real-time Analysis Turns Big Medical Data Into Precision Medicine? (iaria.org)
  • Get a real-time stream of unprocessed hit-level data available within seconds of collection with our Live Stream feature in Adobe Analytics. (adobe.com)
  • With the Live Stream feature in Adobe Analytics, you can access hit-level, unprocessed data in near real time (30 to 90 seconds), which you can use in live-traffic dashboards. (adobe.com)
  • Learn more about real-time data in Adobe Analytics. (adobe.com)
  • Our server-side approach to processing and populating report variables and defining visitor segmentation rules allows you to create real-time segmentation of all online data without creating complex rules on your site. (adobe.com)
  • This critical information is accessible via apps that provide real-time access to information that supports data-driven decisions that can help save lives and property. (esri.com)
  • Whether your team is working in the operations center monitoring the situation and planning for the next operational period, conducting real-time operational briefings, or deployed to the field for coordination, these updates are immediately available wherever they are needed most. (esri.com)
  • To support your decision making, Esri provides you with ready to use real-time information from partners like the federal government and the private sector. (esri.com)
  • If communications are running normally, the data being collected in the field feeds a live dashboard that provides your team with a real-time view of the data being collected for missions like damage assessment. (esri.com)
  • Speak with an expert today about how Esri's solution for emergency management operations can transform your response efforts through a real-time, integrated solution. (esri.com)
  • Real Time PCR is the gold standard for validating gene expression data. (utmb.edu)
  • Upon completion of QC, real-time analysis with be carried out on our ABI 7500 and a detail report generated. (utmb.edu)
  • Delivering real-time data, Intel® Core™ i7 processor-based medical carts improve patient outcomes and provider efficiency. (intel.com)
  • Real-Time Healthcare with Intel Processing. (intel.com)
  • The opposing view is that time does not refer to any kind of "container" that events and objects "move through", nor to any entity that "flows", but that it is instead part of a fundamental intellectual structure (together with space and number) within which humans sequence and compare events. (wikipedia.org)
  • The operational definition leaves aside the question whether there is something called time, apart from the counting activity just mentioned, that flows and that can be measured. (wikipedia.org)
  • The question of how many seconds per second time flows (or one advances through it) is obviously an absurd one, for it suggests that the flow or advance comprises a rate of change with respect to something else-to a sort of hypertime. (britannica.com)
  • Photography, once understood as verifying specific facts, capturing singular moments of time, and preserving explicit memories, is now recognized to have a multifaceted and slippery relationship to the truth and to the past. (nga.gov)
  • It was at such a moment a few years ago when I first realized the power of Joda-Time. (ibm.com)
  • Four items that represent how living each one of the Remarkable Lives values will help create Our Remarkable World in 10 Years Time (it can be e.g. an object or behaviours, or something else! (google.com)
  • Then to put the astonishing parameters of Geologic Time in a proper perspective, consider the following: the last trilobites (proteids) swam in the Permian oceans some 251 million years ago. (amnh.org)
  • An Iranian businessman claims to have mastered time with a machine that allows users to fast forward up to eight years into the future. (youtube.com)
  • These short stories will cover a time period from the late 1930's to the mid 1970's Chapter Two will be by The Investigator Series, covering the writer's experiences from 1960 to 2000, covering his 40 years as an Investigator. (lulu.com)
  • Chapter Three, The Time Travel Series is going to be a series of short stories about the things The MainStreet Writer, The Investigator and The Time Traveler learned during eighty-five years of Time Travel as a Spirit in a man's body. (lulu.com)
  • This post originally stated that the child on the Time cover is 4-years-old. (slate.com)
  • It's normally intended to be opened after a length of time, 25,50, 100 years so that future generations have a record. (usingenglish.com)
  • For such events, the question of which event occurs at a later time depends entirely on what coordinate system you use, with no coordinate system being preferred over any other. (mail-archive.com)
  • The Reaction Time Scholarship is available to students attending Universal Technical Institute or NASCAR Technical Institute. (fastweb.com)
  • When a human subject follows instructions to make a specific response as soon as he can after the presentation of a specific signal, the latency of the response is called reaction time ( RT ). (encyclopedia.com)
  • The second is that of Siegmund Exner, who first used the term "reaction time" in 1873. (encyclopedia.com)
  • Time-intensity methods represent a special form of intensity scaling that is either repeated at short intervals or continuous. (springer.com)
  • The issue of whether daylight savings time (DST) should be abolished comes up at regular intervals, and for good reason. (lewrockwell.com)
  • All of these versions of UT, except for UTC, are based on Earth's rotation relative to distant celestial objects ( stars and quasars ), but with a scaling factor and other adjustments to make them closer to solar time . (wikipedia.org)
  • Blood for most infections is discounts a short dna concentrations found through the zithromax 1 time dose molecule within magnesium-containing. (eyfel.de)
  • At the same time, many short-hours workers in developing and transition countries may be underemployed and thus more likely to fall into poverty. (ilo.org)
  • You will also spend a short period of time shadowing an experienced researcher . (bath.ac.uk)
  • There is still time to take cuttings of pinks, penstemons, salvias, artemisias, lavenders and other silver-leaved or short-lived plants. (telegraph.co.uk)
  • Did you know men's nutrition needs change at different times of the lifespan? (daa.asn.au)
  • World of Work 60, Aug. 2007 - Green jobs: Climate change in the world of work, Working time around the world. (ilo.org)
  • For many, the time change associated with daylight savings time 1 (DST) also means spending several days or even weeks feeling generally off-kilter. (lewrockwell.com)
  • When daylight savings gets added into the mix, this risk tends to become even more pronounced One 2012 study 6 found that heart attacks increased by 10 percent on the Monday and Tuesday following the time change to DST. (lewrockwell.com)
  • This change comes from the deepest and most difficult problems facing contemporary science: those having to do with the nature of time. (mail-archive.com)
  • Ordinary change can, of course, be represented in a space-time picture: for example, a particle at rest is represented by a straight line and an oscillating particle by a wavy line. (britannica.com)
  • As exemplified by Vera Lutter's (b. 1960) Ca' del Duca Sforza, Venice II: January 13-14, 2008 (2008), a breathtaking photograph of Venice made over a period of two days, these artists work against the modernist attraction to speed and instantaneity and deliberately plan their exposures, which often extend over long periods of time. (nga.gov)
  • With the interest thus aroused in the variability of human behavior, and with the concurrent development of accurate timing apparatus designed to eliminate this factor from astronomical observations, there eventually resulted the measurement of true RT s by two astronomers. (encyclopedia.com)
  • Time is used to define other quantities-such as velocity-so defining time in terms of such quantities would result in circularity of definition. (wikipedia.org)
  • These verbal skills have to be picked up in very complex ways (partly by ostension), and it is not surprising that the meaning of the word time cannot be distilled into a neat verbal definition. (britannica.com)
  • But the question is, have we had time to adapt sufficiently to make it a healthy food? (blogspot.com)
  • Do significantly take a zithromax 1 time dose functional antibiotic to cure make up for a missed one. (eyfel.de)
  • Nearly a century after adopting its first international standard on working time, a new ILO study estimates that one in five workers around the world - or over 600 million persons - are still working more than 48 hours a week, often merely to make ends meet. (ilo.org)
  • The fourth section, 'Framing Time and Place,' examines how photographs-by artists as diverse as Idris Khan (b. 1978), Andrew Moore (b. 1957), Mark Ruwedel (b. 1954), and Mikhael Subotzky (b. 1981) and Patrick Waterhouse (b. 1981), can make the past vividly present through the depiction of urban vistas and landscapes. (nga.gov)
  • The stupider the idea sounds, the more likely it'll make a great Epic Meal Time video. (forbes.com)
  • The documents, which were sent to The New York Times through encrypted email by an unidentified party, include a selfie dated May 9, 2013, of the two lying in bed. (nytimes.com)
  • She previously worked at the New Delhi bureau of The New York Times. (wsj.com)
  • The fallout from "a sexual battery" was so traumatic that it hindered Mr. Bennett's work and income and threatened his mental health, according to a notice of intent to sue that his lawyer sent in November to Richard Hofstetter, Mr. Bourdain's longtime lawyer, who was also representing Ms. Argento at the time. (nytimes.com)
  • However, if the work within the frame exceeds this time budget, for whatever reason, then one or more frames is skipped, resulting in inconsistent response, processing, and rendering times, which hurts the user experience. (w3.org)
  • Women's availability for paid work appears to be constrained by the time they devote to their household/domestic responsibilities. (ilo.org)
  • Do you work for Lynn Time Bank? (idealist.org)
  • Divided into five sections, The Memory of Time examines work made from the early 1990s to the present by artists who explore these complex issues. (nga.gov)
  • This also explains why contented pensioners, like myself, often wonder how they ever found time to go to work. (newscientist.com)
  • This guest ensures that dramatically on zithromax 1 time dose the cheapest slijm site infection rate. (eyfel.de)
  • 2. Site of tumor  Rapidly proliferating tumor has poor LC with increase in time eg- head & neck, NSCLC  In slowly growing tumor eg. (slideshare.net)
  • Add to that the fact that many people descend from groups that have been eating grains for far less time than that, and you begin to see the problem. (blogspot.com)
  • Perhaps we simply weren't wired to ponder the number of stars in the sky… the multitude of sand grains on a beach… or the "deep time" age of the universe. (amnh.org)
  • Nevertheless, diverse fields such as business, industry, sports, the sciences, and the performing arts all incorporate some notion of time into their respective measuring systems. (wikipedia.org)
  • Carrie Goldberg, her lawyer who handled the matter, read email messages from The Times, according to two people familiar with the case, but she has not responded. (nytimes.com)
  • Check the box if you do not wish to receive promotional offers via email from TIME. (time.com)
  • For example, in neoclassical, economic theory, which is anchored in the study of equilibria of markets and games, time is largely abstracted away. (mail-archive.com)
  • In the Time magazine story, which is largely a profile of attachment guru William Sears, he answers this objection by arguing that attachment parenting is perfect for working mothers because as soon as they get home they can instantly rebond with their babies by strapping them up in a sling and then sleeping with them the whole night. (slate.com)
  • One of the features of time that puzzled the Neoplatonist philosopher Augustine of Hippo , in the 5th century ce , was the difficulty of defining it. (britannica.com)
  • Prior to the introduction of standard time , each municipality throughout the civilized world set its official clock, if it had one, according to the local position of the Sun (see solar time ). (wikipedia.org)
  • Standard time, as originally proposed by Scottish-Canadian Sir Sandford Fleming in 1879, divided the world into twenty-four time zones , each one covering 15 degrees of longitude. (wikipedia.org)
  • An oscilloscope is a tool commonly used to visualize real-world signals in the time domain. (wikipedia.org)
  • GENEVA - According to a new ILO study, Working time around the world: Trends in working hours, laws and policies in a global comparative perspective ( See note 1 ), an estimated 22 per cent of the global workforce, or 614.2 million workers, are working "excessively" long hours. (ilo.org)
  • Each Chapter is a Chapter of The Writers Life, as he Traveled through Time & Space in a World of Newness. (lulu.com)
  • That conversation started The Time Traveler on a more in-depth study of the Invisible World around him. (lulu.com)
  • It was the beginning of a new adventure in the Life of the Time Traveler, as he searched for more about The Invisible World all around him. (lulu.com)
  • Charlie The Time Traveler, will give you enough about this invisible World around you to get you started on your search on how you can use these invisible powers to 'Create' your own World. (lulu.com)
  • The Australian city of Melbourne, recently a coronavirus hotspot in the country, is the latest to announce it will lift restrictions after going 24 hours without a single new infection or death for the first time in four months, in sharp contrast to the other side of the world where new infections are spiking in the U.S. and in Europe, and fresh lockdowns are being introduced. (forbes.com)
  • Among study participants without a history of psychiatric illness, those with moderate to severe TBI were 4 times (95% confidence interval [CI], 2.4 to 6.8) more likely to sustain any psychiatric illness in the 6 months following a TBI than those without a TBI. (psychiatrictimes.com)
  • Time has long been an important subject of study in religion, philosophy, and science, but defining it in a manner applicable to all fields without circularity has consistently eluded scholars. (wikipedia.org)
  • This groundbreaking study of over 50 countries reviews global working time issues - including national laws and policies, trends in actual working hours, the specific experiences of different economic sectors and different types of workers, as well as the implications for future policies relating to working time. (ilo.org)
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