Thyroxine
Thyroxine-Binding Proteins
Triiodothyronine
Hypothyroidism
Thyrotropin
Thyroid Hormones
Triiodothyronine, Reverse
Hyperthyroidism
Thyroid Gland
Iodide Peroxidase
Congenital Hypothyroidism
Iodine Isotopes
Iodine
Thyronines
Propylthiouracil
Prealbumin
Radioimmunoassay
Methimazole
Antithyroid Agents
Goiter
Thyroglobulin
Thyroxine-Binding Globulin
Thyrotropin-Releasing Hormone
Serum Globulins
Myxedema
Dialysis
Iodine Radioisotopes
Thyrotoxicosis
Graves Disease
Serum Albumin
Reagent Kits, Diagnostic
Euthyroid Sick Syndromes
Norethandrolone
Potassium Iodide
Immunoassay
Liver
Thyroiditis, Autoimmune
Hypophysectomy
Monoiodotyrosine
Carbimazole
Diiodotyrosine
Pregnancy
Perchlorates
Growth Hormone
Thyroiditis
Serum Albumin, Radio-Iodinated
Thiouracil
Reference Values
The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario. (1/3269)
The thyroid glands of coho salmon collected at different stages of their anadromous migration exhibited progressive and extensive hyperplasia and hypertrophy. The incidence of overt nodule formation rose from 5% in fish collected in August to 24% in fish collected in October. The histological picture of the goiters was similar to that found in thiourea-treated teleosts and thiouracil-treated mammals. There was a concomitant, significant decrease in serum thyroxine and triiodothyronine values between September and October (thyroxine, 1.0+/-0.3 mug/100 ml and 0.4 mug/100 ml in September and October, respectively; triiodothyronine, 400.3+/-51.6 ng/100 ml and 80.2 ng/100 ml in September and October, respectively) and marked hypertrophy and hyperplasia of thyrotrophs. These data indicate a progressive hypothyroid condition which, although it may be linked to iodide deficiency, may well be enhanced by other environmental factors. The evidence for involvement of other factors is discussed. (+info)Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. (2/3269)
We have examined the effects of l-thyroxine (T4) on the activation of signal transducer and activator of transcription 3 (STAT3) and on the STAT3-dependent induction of c-Fos expression by epidermal growth factor (EGF). T4, at a physiological concentration of 100 nM, caused tyrosine phosphorylation and nuclear translocation (i.e. activation) of STAT3 in HeLa cells in as little as 10-20 min. Activation by T4 of STAT3 was maximal at 30 min (15+/-4-fold enhancement; mean+/-S.E.M.) in 18 experiments. This effect was reproduced by T4-agarose (100 nM) and blocked by CGP 41251, genistein, PD 98059 and geldanamycin, inhibitors of protein kinase C (PKC), protein tyrosine kinase (PTK), mitogen-activated protein kinase (MAPK) kinase and Raf-1 respectively. Tyrosine-phosphorylated MAPK also appeared in nuclear fractions within 10 min of treatment with T4. In the nuclear fraction of T4-treated cells, MAPK immunoprecipitate also contained STAT3. The actions of T4 were similar in HeLa and CV-1 cells, which lack thyroid hormone receptor (TR), and in TR-replete skin fibroblasts (BG-9). T4 also potentiated the EGF-induced nuclear translocation of activated STAT1alpha and STAT3 and enhanced the EGF-stimulated expression of c-Fos. Hormone potentiation of EGF-induced signal transduction and c-Fos expression was inhibited by CGP 41251, geldanamycin and PD 98059. Therefore the non-genomically induced activation by T4 of STAT3, and the potentiation of EGF by T4, require activities of PKC, PTK and an intact MAPK pathway. (+info)Inhibition by lead of production and secretion of transthyretin in the choroid plexus: its relation to thyroxine transport at blood-CSF barrier. (3/3269)
Long-term, low-dose Pb exposure in rats is associated with a significant decrease in transthyretin (TTR) concentrations in the CSF. Since CSF TTR, a primary carrier of thyroxine in brain, is produced and secreted by the choroid plexus, in vitro studies were conducted to test whether Pb exposure interferes with TTR production and/or secretion by the choroid plexus, leading to an impaired thyroxine transport at the blood-CSF barrier. Newly synthesized TTR molecules in the cultured choroidal epithelial cells were pulse-labeled with [35S]methionine. [35S]TTR in the cell lysates and culture media was immunoprecipitated and separated by SDS-PAGE, and quantitated by autoradiography and liquid scintillation counting. Pb treatment did not significantly alter the protein concentrations in the culture, but inhibited the synthesis of total [35S]TTR (cells + media), particularly during the later chase phase. Two-way ANOVA of the chase phase revealed that Pb exposure (30 microM) significantly suppressed the rate of secretion of [35S]TTR compared to the controls (p < 0.05). Accordingly, Pb treatment caused a retention of [35S]TTR by the cells. In a two-chamber transport system with a monolayer of epithelial barrier, Pb exposure (30 microM) reduced the initial release rate constant (kr) of [125I]T4 from the cell monolayer to the culture media and impeded the transepithelial transport of [125I]T4 from the basal to apical side of epithelial cells by 27%. Taken together, these in vitro data suggest that sequestration of Pb in the choroid plexus hinders the production and secretion of TTR by this tissue. Consequently, this may alter the transport of thyroxine across this blood-CSF barrier. (+info)Pseudogout attack associated with chronic thyroiditis and Sjogren's syndrome. (4/3269)
A 66-year-old woman, diagnosed with chronic thyroiditis at age 63, presented with anorexia and fatigue. Therapy for the chronic thyroiditis consisted of levothyroxine sodium (100 microg/day). Her symptoms were attributed to the insufficient supply of levothyroxine sodium. Following a dosage increase to 150 microg/day, she suffered from an acute attack of pseudogout. Clinical features were complicated by Sjogren's syndrome, which appeared after treatment onset. Pseudogout was effectively treated by colchicine after administration of diclofenac sodium failed to alleviate the symptoms. Pseudogout is a recognized complication of thyroid replacement therapy, but association with Sjogren's syndrome has not been previously reported. (+info)Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats. (5/3269)
AIM: To develop a cardiac hypertrophic model in rats. METHODS: Rats were i.p. levothyroxine 0.5 mg.kg-1.d-1 x 10 d. The action potentials of right papillary muscles were recorded by standard glass-microelectrode technique. The left coronary artery was ligated followed by reperfusion and the apparent infarcted zone (AIZ) was determined by tetracycline fluoresence, and the superoxide dismutase (SOD) activity and malondialdehyde (MDA) product in myocardium were also measured. RESULTS: In the rats treated by levothyroxine, the heart was hypertrophic and the action potential duration (APD) and effective refractory period (ERP) were prolonged, the APD20, APD50, APD90, and ERP were prolonged by 80%, 79%, 74%, and 68%, respectively. No changes in resting potential (RP), action potential amplitude (APA), and Vmax were produced. The incidence of heart arrest (8/8) and the risk of death (67 +/- 0) induced by ischemia-reperfusion in rats with hypertrophic heart was higher than those in normal rats (4/10 and 44 +/- 19, respectively). The AIZ was expanded markedly in hypertrophic heart, and attenuated by lidocaine and propranolol. CONCLUSION: Levothyroxine-induced heart hypertrophy is a suitable model for severe ischemia and arrhythmias in rats. (+info)Histamine aggravated levothyroxine-induced cardiomyopathy in guinea pigs. (6/3269)
AIM: To study effects of histamine on cardiomyopathy. METHODS: Cardiomyopathy model was developed in guinea pig by i.p. levothyroxine 0.5 mg.kg-1.d-1 for 10 d. Langendroff's hearts were perfused. ECG and contractile force were recorded. Histamine (5 micrograms) was given by intra-aortic injection. Histamine content of coronary venous effluent was determined fluorometrically. RESULTS: Attack of histamine on cardiomyopathy was severer than that in normal hearts. Tachycardia was more prominent; atrioventricular conduction block occurred earlier; decrease in coronary flow was more marked. Uptakes of histamine were 37% in the model and 19% in the normal hearts (P < 0.01). CONCLUSION: Histamine aggravated levothyroxine-cardiomyopathy. (+info)Hormonal changes in thalassaemia major. (7/3269)
Patients with severe thalassaemia major suffer endocrine and other abnormalities before their eventual death from iron overload due to repeated blood transfusions. The endocrine status of 31 thalassaemic patients aged 2-5 to 23 years was investigated. Exact data were available on the rate and duration of blood transfusion in all of them and in many the liver iron concentration was also known. Although the patients were euthyroid, the mean serum thyroxine level was significantly lower, and the mean thyrotrophic hormone level significantly higher, compared with the values found in normal children. Forty oral glucose tolerance tests with simultaneous insulin levels were performed in 19 children, of whom 5 developed symptomatic diabetes and one had impaired tolerance. Previous tests on all 6 patients were available and some showed raised insulin levels possibly due to insulin resistance. 2 patients had clinical hypoparathyroidism and are described. The parathyroid hormone levels determined by radioimmunoassay in 25 patients were below the mean for the age group in all and outside the reference range in 16. Nonfasting plasma calcium levels were not reduced. Puberty was delayed in some patients. Concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) measured in urine from 7 girls and 5 boys showed considerable variation. In the boys there was an overall tendency for FSH and LH excretion to be low with regard to age, but with respect to puberty rating FSH exretions were normal or low and LH normal or raised. The girls showed a tendency for LH but not FSH excretion to be raised in relation to puberty rating. The severity of the endocrine changes was related to the degree of iron loading and is discussed in relation to previous work in which the iron loading has rarely been accurately indicated nor parathyroid status assessed. (+info)Developmental aspects of glutathione S-transferase B (ligandin) in rat liver. (8/3269)
The postnatal development in male Sprague-Dawley rats of hepatic glutathione S-transferase B (ligandin) in relation to the other glutathione S-transferases is described. The concentration of glutathione S-transferase B in 1-day-old male rats is about one-fifth of that in adult animals. The enzyme reaches adult concentrations 4-5 weeks later. When assessed by substrate specificity or immunologically, the proportion of transferase B relative to the other glutathione S-transferases is high during the first week after birth. At this age, 67.5% of the transferase activity towards 1-chloro-2,4-dinitrobenzene is immunoprecipitable by anti-(transferase B), compared with about 50% in adults and older pups. Between the second and the fifth postnatal week, the fraction of transferase B increases in parallel fashion with the other transferases in hepatic cytosol. Neither L-thyroxine nor cortisol induce a precocious increase in glutathione S-transferase activity. Phenobarbital did induce transferase activity towards 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene in both pups and adults. The extent of induction by phenobarbital was a function of basal activity during development such that the percentage stimulation remained constant from 5 days postnatally to adulthood. (+info)Thyroxine, also known as T4, is a hormone produced by the thyroid gland in the neck. It plays a crucial role in regulating metabolism, growth, and development in the body. In the medical field, thyroxine is often prescribed to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormones. In this case, thyroxine is given to replace the missing hormone and help restore normal metabolic function. Thyroxine is also used to treat certain types of thyroid cancer, as well as to prevent the recurrence of thyroid cancer after surgery. In some cases, thyroxine may be used to treat other conditions, such as Turner syndrome, a genetic disorder that affects females. Thyroxine is typically taken orally in the form of a tablet or liquid, and the dosage is adjusted based on the patient's individual needs and response to treatment. It is important to follow the instructions provided by a healthcare provider when taking thyroxine, as taking too much or too little can have serious consequences.
Thyroxine-binding proteins (TBPs) are proteins that bind to thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3), in the bloodstream. There are three main types of TBPs: thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), and albumin. TBG is the most abundant TBP in the blood, accounting for about 75% of the total TBP concentration. It is synthesized in the liver and binds to T4 and T3 with high affinity, preventing their degradation and transport to target tissues. TBG also plays a role in regulating the availability of thyroid hormones to tissues. TBPA is a minor TBP that is synthesized in the liver and binds to T4 and T3 with lower affinity than TBG. It is involved in the transport of thyroid hormones to tissues and also plays a role in regulating thyroid hormone levels. Albumin is a major plasma protein that binds to T4 and T3 with low affinity. It is synthesized in the liver and plays a role in the transport of thyroid hormones to tissues. TBPs play an important role in regulating thyroid hormone levels in the body. Changes in the levels of TBPs can affect the availability of thyroid hormones to tissues and can lead to thyroid hormone disorders.
Triiodothyronine, also known as T3, is a hormone produced by the thyroid gland. It plays a crucial role in regulating metabolism, growth, and development in the body. T3 is synthesized from thyroxine (T4), another thyroid hormone, by removing an iodine atom from each of the three iodine atoms in T4. In the medical field, T3 is often measured as a diagnostic tool to evaluate thyroid function. Abnormal levels of T3 can indicate a variety of thyroid disorders, including hypothyroidism (low thyroid hormone levels) and hyperthyroidism (high thyroid hormone levels). T3 levels may also be monitored in patients with certain conditions, such as heart disease, to assess their overall health and response to treatment.
Hypothyroidism is a medical condition in which the thyroid gland does not produce enough thyroid hormones. The thyroid gland is a small gland located in the neck that plays a crucial role in regulating the body's metabolism. When the thyroid gland does not produce enough hormones, the body's metabolism slows down, leading to a range of symptoms such as fatigue, weight gain, cold intolerance, dry skin, hair loss, constipation, and depression. Hypothyroidism can be caused by a variety of factors, including autoimmune disorders, iodine deficiency, radiation therapy, surgery, and certain medications. It is typically diagnosed through blood tests that measure the levels of thyroid hormones in the body. Treatment for hypothyroidism typically involves taking synthetic thyroid hormone medication to replace the hormones that the body is not producing enough of. With proper treatment, most people with hypothyroidism can manage their symptoms and live normal, healthy lives.
Thyrotropin, also known as thyroid-stimulating hormone (TSH), is a hormone produced by the anterior pituitary gland in the brain. It plays a crucial role in regulating the function of the thyroid gland, which is responsible for producing hormones that control metabolism in the body. TSH stimulates the thyroid gland to produce and release thyroid hormones, including thyroxine (T4) and triiodothyronine (T3). These hormones regulate the body's metabolism, affecting how the body uses energy and how quickly it burns calories. In the medical field, TSH is often measured as part of routine blood tests to assess thyroid function. Abnormal levels of TSH can indicate a variety of thyroid disorders, including hypothyroidism (an underactive thyroid) and hyperthyroidism (an overactive thyroid). TSH levels can also be affected by other medical conditions, such as pituitary tumors or certain medications.
Thyroid hormones are hormones produced by the thyroid gland, a small gland located in the neck. There are two main types of thyroid hormones: thyroxine (T4) and triiodothyronine (T3). These hormones play a crucial role in regulating metabolism, growth, and development in the body. Thyroxine (T4) is the primary thyroid hormone produced by the thyroid gland. It is converted into triiodothyronine (T3) in the body, which is the more active thyroid hormone. T3 and T4 are responsible for regulating the body's metabolism, which is the process by which the body converts food into energy. They also play a role in regulating the body's growth and development, as well as the function of the heart and nervous system. Thyroid hormones are regulated by the hypothalamus and the pituitary gland, which are located in the brain. The hypothalamus produces a hormone called thyrotropin-releasing hormone (TRH), which stimulates the pituitary gland to produce thyroid-stimulating hormone (TSH). TSH then stimulates the thyroid gland to produce T4 and T3. Abnormal levels of thyroid hormones can lead to a variety of health problems, including hyperthyroidism (too much thyroid hormone), hypothyroidism (too little thyroid hormone), and thyroid nodules or cancer. Treatment for thyroid disorders typically involves medication to regulate the levels of thyroid hormones in the body.
Triiodothyronine, also known as T3, is a hormone produced by the thyroid gland that plays a crucial role in regulating metabolism in the body. Reverse T3, also known as rT3, is a form of T3 that is converted from T4 (thyroxine) in the liver and kidneys. It is not as biologically active as T3 and is often considered a waste product. In some cases, levels of rT3 may be elevated in the blood, which can indicate an underlying thyroid disorder or other health issue.
Hyperthyroidism is a medical condition in which the thyroid gland produces excessive amounts of thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3). This overproduction of hormones can cause an array of symptoms, including weight loss, increased heart rate, anxiety, irritability, tremors, and heat intolerance. Hyperthyroidism can be caused by a variety of factors, including Graves' disease, thyroiditis, and thyroid nodules. It can also be caused by taking too much thyroid hormone medication or by consuming excessive amounts of iodine. Treatment for hyperthyroidism typically involves medications to reduce the production of thyroid hormones, radioactive iodine therapy to destroy overactive thyroid cells, or surgery to remove part or all of the thyroid gland. The specific treatment approach depends on the underlying cause of the condition and the severity of the symptoms.
Iodide Peroxidase (also known as Thyroid Peroxidase) is an enzyme that plays a critical role in the production of thyroid hormones in the thyroid gland. It catalyzes the oxidation of iodide ions to form iodine, which is then incorporated into thyroglobulin, a large protein produced by thyroid cells. The iodinated thyroglobulin is then broken down into smaller thyroid hormones, thyroxine (T4) and triiodothyronine (T3), which are essential for regulating metabolism in the body. In the medical field, the measurement of thyroid peroxidase antibodies (TPOAb) is often used as a diagnostic tool for autoimmune thyroid diseases such as Hashimoto's thyroiditis and Graves' disease. In these conditions, the immune system mistakenly attacks the thyroid gland, leading to inflammation and damage to the gland's ability to produce thyroid hormones. The presence of TPOAb in the blood can indicate an autoimmune response and help guide treatment decisions.
Congenital hypothyroidism is a medical condition that occurs when the thyroid gland does not produce enough thyroid hormones during fetal development or shortly after birth. This can lead to a range of symptoms, including growth retardation, delayed development, and intellectual disability. The thyroid gland is responsible for producing hormones that regulate metabolism, which is the process by which the body uses energy. When the thyroid gland does not produce enough hormones, the body's metabolism slows down, leading to the symptoms of hypothyroidism. Congenital hypothyroidism is usually diagnosed through newborn screening tests, which check for the presence of thyroid hormones in a baby's blood. If the test is positive, further testing is done to confirm the diagnosis and determine the underlying cause of the condition. Treatment for congenital hypothyroidism typically involves lifelong thyroid hormone replacement therapy, which involves taking medication to replace the missing thyroid hormones. With proper treatment, most babies with congenital hypothyroidism can grow and develop normally.
In the medical field, iodine isotopes refer to different forms of the element iodine that have different atomic weights due to the presence of different numbers of neutrons in their nuclei. The most commonly used iodine isotopes in medicine are iodine-123 (I-123) and iodine-131 (I-131). I-123 is a short-lived isotope with a half-life of 13.2 hours, which makes it useful for imaging the thyroid gland and other organs. It is often used in diagnostic procedures such as thyroid scans and radioiodine uptake tests. I-131, on the other hand, is a longer-lived isotope with a half-life of 8 days. It is commonly used in the treatment of thyroid cancer and hyperthyroidism. In these treatments, I-131 is administered to the patient, and it is taken up by the thyroid gland, where it emits beta particles that destroy the cancerous or overactive cells. Overall, iodine isotopes play an important role in medical imaging and treatment, particularly in the diagnosis and management of thyroid disorders.
Iodine is a chemical element that is essential for the proper functioning of the thyroid gland, which is located in the neck and plays a crucial role in regulating metabolism. In the medical field, iodine is commonly used as a dietary supplement to prevent and treat iodine deficiency disorders, which can lead to a range of health problems, including goiter, hypothyroidism, and cretinism. Iodine is also used in medical imaging procedures, such as radioiodine scans, which are used to diagnose and monitor thyroid disorders. In these procedures, a small amount of radioactive iodine is administered to the patient, and the thyroid gland's ability to absorb and store the iodine is measured using a special camera. In addition to its use in medicine, iodine is also used in the production of certain chemicals and pharmaceuticals, as well as in the manufacturing of dyes, pigments, and other industrial products.
Thyroid diseases refer to a group of disorders that affect the thyroid gland, a small endocrine gland located in the neck that produces hormones that regulate metabolism. The thyroid gland produces two main hormones: thyroxine (T4) and triiodothyronine (T3), which are essential for regulating the body's metabolism, growth, and development. There are several types of thyroid diseases, including: 1. Hypothyroidism: This is a condition in which the thyroid gland does not produce enough thyroid hormones. Symptoms of hypothyroidism include fatigue, weight gain, cold intolerance, dry skin, and depression. 2. Hyperthyroidism: This is a condition in which the thyroid gland produces too much thyroid hormone. Symptoms of hyperthyroidism include weight loss, rapid heartbeat, anxiety, and tremors. 3. Thyroid nodules: These are small growths on the thyroid gland that can be benign or malignant. 4. Thyroiditis: This is an inflammation of the thyroid gland that can cause symptoms such as pain, swelling, and difficulty swallowing. 5. Thyroid cancer: This is a rare type of cancer that affects the thyroid gland. Symptoms of thyroid cancer may include a lump in the neck, difficulty swallowing, and hoarseness. Thyroid diseases can be diagnosed through blood tests, imaging studies, and physical examination. Treatment options for thyroid diseases depend on the specific condition and may include medication, surgery, or radiation therapy.
Thyronines are hormones produced by the thyroid gland that play a crucial role in regulating metabolism in the body. There are two main types of thyronines: thyroxine (T4) and triiodothyronine (T3). Thyroxine is the primary hormone produced by the thyroid gland and is converted into triiodothyronine in the body. Both hormones are essential for regulating metabolism, which is the process by which the body uses energy from food. Thyroxine and triiodothyronine help to control the rate at which the body burns calories, affects the body's sensitivity to insulin, and regulates the growth and development of tissues. Thyroid hormones are also important for maintaining a healthy heart rate, regulating body temperature, and supporting normal brain function. Imbalances in thyronine levels can lead to a variety of health problems, including hypothyroidism (low levels of thyroid hormones) and hyperthyroidism (high levels of thyroid hormones).
Propylthiouracil is a medication that is used to treat hyperthyroidism, a condition in which the thyroid gland produces too much thyroid hormone. It works by blocking the production of thyroid hormones in the thyroid gland. Propylthiouracil is usually taken by mouth in tablet form and is often used in combination with other medications to treat hyperthyroidism. It can also be used to treat certain types of goiter, an enlargement of the thyroid gland. Common side effects of propylthiouracil include nausea, vomiting, diarrhea, headache, and skin rash. It is important to follow the instructions of your healthcare provider when taking propylthiouracil and to report any side effects to your healthcare provider.
Prealbumin is a type of protein that is produced in the liver and is found in the bloodstream. It is a precursor to albumin, which is the most abundant protein in the blood and plays a key role in maintaining the osmotic pressure of blood vessels and transporting nutrients and hormones throughout the body. Prealbumin levels can be measured in the blood as a way to assess liver function and nutritional status. Low levels of prealbumin may indicate liver disease, malnutrition, or other conditions that affect protein synthesis in the liver. High levels of prealbumin may indicate liver disease or other conditions that cause the liver to produce more prealbumin than normal.
Hyperthyroxinemia is a medical condition characterized by an abnormally high level of thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3), in the bloodstream. This can occur due to various reasons, including overproduction of thyroid hormones by the thyroid gland, decreased clearance of thyroid hormones from the bloodstream, or a combination of both. Hyperthyroxinemia can lead to a range of symptoms, including weight loss, increased heart rate, nervousness, anxiety, irritability, tremors, and difficulty sleeping. In severe cases, it can cause more serious complications such as heart problems, bone loss, and eye problems. Treatment for hyperthyroxinemia typically involves medications to reduce the production of thyroid hormones or to block their absorption in the bloodstream. In some cases, surgery may be necessary to remove part or all of the thyroid gland. It is important to diagnose and treat hyperthyroxinemia promptly to prevent complications and improve quality of life.
Methimazole is a medication that is used to treat hyperthyroidism, a condition in which the thyroid gland produces too much thyroid hormone. It works by inhibiting the production of thyroid hormones in the thyroid gland. Methimazole is usually taken by mouth, and the dosage and duration of treatment will depend on the severity of the condition and the response of the patient to the medication. It is important to follow the instructions of a healthcare provider when taking methimazole, as it can have side effects and may interact with other medications.
Iopanoic acid is a medication used in the medical field as a contrast agent for diagnostic imaging procedures such as computed tomography (CT) scans. It is a type of iodinated contrast agent that is injected into the bloodstream to enhance the visibility of organs and tissues on the CT scan. Iopanoic acid is particularly useful for imaging the liver, gallbladder, and bile ducts, as well as for evaluating blood vessels in the brain and spinal cord. It is usually administered as an intravenous injection and is well-tolerated by most patients. However, like all contrast agents, it can cause allergic reactions in some individuals, so it is important to inform your healthcare provider if you have a history of allergies or other medical conditions before receiving an iopanoic acid injection.
Antithyroid agents are medications that are used to treat hyperthyroidism, a condition in which the thyroid gland produces too much thyroid hormone. These medications work by reducing the production of thyroid hormones in the gland. There are several different types of antithyroid agents, including methimazole (Tapazole), propylthiouracil (PTU), and carbimazole (Carbimazole). These medications are typically prescribed for people who have Graves' disease, a type of hyperthyroidism that is caused by an autoimmune disorder, or for people who have had radioactive iodine therapy or surgery to treat their hyperthyroidism. Antithyroid agents can be effective in controlling the symptoms of hyperthyroidism and can help to prevent complications from the condition. However, they can also cause side effects, such as skin rash, hair loss, and liver problems.
Goiter is a medical condition characterized by an enlargement of the thyroid gland, which is located in the neck. The thyroid gland is responsible for producing hormones that regulate metabolism, and an overactive or underactive thyroid gland can cause the gland to become enlarged. There are several types of goiter, including simple goiter, which is caused by a lack of iodine in the diet, and toxic goiter, which is caused by an overactive thyroid gland. Other types of goiter include nodular goiter, which is characterized by the presence of nodules or lumps in the thyroid gland, and struma nodosa, which is a rare type of goiter that is characterized by the presence of large, firm nodules in the thyroid gland. Goiter can cause a variety of symptoms, including difficulty swallowing, hoarseness, and a visible swelling in the neck. In some cases, goiter can also cause high blood pressure, an irregular heartbeat, and other complications. Treatment for goiter depends on the underlying cause and may include medication, surgery, or radioactive iodine therapy.
Thyroglobulin is a large glycoprotein that is synthesized and secreted by the thyroid gland. It is the precursor protein for thyroid hormones, thyroxine (T4) and triiodothyronine (T3), which are essential for regulating metabolism in the body. In the medical field, thyroglobulin is often used as a diagnostic marker for thyroid cancer. When thyroid cells become cancerous, they continue to produce thyroglobulin even after the gland has been removed. This means that measuring thyroglobulin levels in the blood can help doctors detect and monitor thyroid cancer. Thyroglobulin levels may also be used to monitor the effectiveness of treatment for thyroid cancer. If the cancer is responding well to treatment, the thyroglobulin levels should decrease. If the levels remain high or increase, it may indicate that the cancer has returned or is still present. In addition to its use in thyroid cancer diagnosis and monitoring, thyroglobulin is also used as a marker for other types of cancer, such as ovarian cancer and breast cancer.
Thyroxine-Binding Globulin (TBG) is a protein found in the blood that binds to thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3). TBG is produced by the liver and plays a crucial role in regulating the levels of thyroid hormones in the body. TBG can bind up to 95% of the circulating thyroxine in the blood, making it the primary carrier of thyroid hormones in the bloodstream. The amount of TBG in the blood can be affected by various factors, including pregnancy, liver disease, and certain medications. In the medical field, TBG levels are often measured as part of thyroid function tests to assess thyroid hormone levels and diagnose thyroid disorders. Abnormal TBG levels can indicate problems with thyroid hormone metabolism or liver function.
Thyrotropin-Releasing Hormone (TRH) is a hormone produced by the hypothalamus, a region of the brain that plays a crucial role in regulating various bodily functions, including metabolism, growth, and development. TRH is responsible for stimulating the release of thyroid-stimulating hormone (TSH) from the anterior pituitary gland, which in turn stimulates the thyroid gland to produce thyroid hormones. Thyroid hormones are essential for regulating metabolism, growth, and development in the body. They help to regulate the body's energy levels, maintain body temperature, and support the growth and development of tissues and organs. TRH is also involved in regulating the sleep-wake cycle, appetite, and mood. It is often used in medical treatments for conditions such as hypothyroidism, which is a condition characterized by low levels of thyroid hormones, and for disorders of the sleep-wake cycle, such as insomnia.
Serum globulins are a group of proteins found in the blood plasma that are responsible for various functions in the body. They are classified into four main categories: albumin, alpha globulins, beta globulins, and gamma globulins. Albumin is the most abundant serum protein, accounting for about 50-60% of total serum protein. It plays a crucial role in maintaining the osmotic pressure of the blood, transporting hormones and fatty acids, and serving as a reservoir for various substances. Alpha globulins are a diverse group of proteins that include haptoglobin, alpha-1 acid glycoprotein, and alpha-2 macroglobulin. They play a role in the immune system, as well as in the transport and metabolism of various substances. Beta globulins include transferrin, which transports iron in the blood, and haptoglobin, which binds to free hemoglobin and helps to remove it from the bloodstream. Gamma globulins, also known as immunoglobulins, are the most diverse group of serum proteins and are responsible for the immune response. They are produced by B cells in response to foreign substances and are involved in the destruction of pathogens and the production of antibodies. Abnormal levels of serum globulins can indicate various medical conditions, such as liver disease, kidney disease, or certain types of cancer.
Myxedema is a severe form of hypothyroidism, which is a condition in which the thyroid gland does not produce enough thyroid hormones. Myxedema is characterized by a thickening and swelling of the skin, particularly in the face, neck, and limbs, as well as dry, brittle hair and nails, weight gain, cold intolerance, fatigue, and depression. It can also cause slowed heart rate, low blood pressure, and decreased mental function. Myxedema is a medical emergency and requires prompt treatment with thyroid hormone replacement therapy.
Diiodothyronines are a group of hormones that are produced by the thyroid gland. They are composed of two iodine atoms and are responsible for regulating the body's metabolism. The two main diiodothyronines are thyroxine (T4) and triiodothyronine (T3). T4 is the more abundant of the two hormones, but T3 is more potent and has a faster onset of action. Diiodothyronines play a critical role in maintaining normal growth and development, as well as regulating the body's energy metabolism. Abnormal levels of diiodothyronines can lead to a variety of health problems, including hyperthyroidism (too much thyroid hormone) and hypothyroidism (too little thyroid hormone).
Iodine radioisotopes are radioactive forms of the element iodine that are used in medical imaging and treatment procedures. These isotopes have a nucleus that contains an odd number of neutrons, which makes them unstable and causes them to emit radiation as they decay back to a more stable form of iodine. There are several different iodine radioisotopes that are commonly used in medical applications, including iodine-123, iodine-125, and iodine-131. Each of these isotopes has a different half-life, which is the amount of time it takes for half of the radioactive material to decay. The half-life of an iodine radioisotope determines how long it will remain in the body and how much radiation will be emitted during that time. Iodine radioisotopes are often used in diagnostic imaging procedures, such as thyroid scans, to help doctors visualize the structure and function of the thyroid gland. They may also be used in therapeutic procedures, such as radiation therapy, to treat thyroid cancer or other thyroid disorders. In these cases, the radioactive iodine is administered to the patient and selectively absorbed by the thyroid gland, where it emits radiation that damages or destroys cancerous cells.
Thyrotoxicosis is a medical condition characterized by an overactive thyroid gland, which leads to an excessive production of thyroid hormones. The thyroid gland is a small endocrine gland located in the neck, and it plays a crucial role in regulating the body's metabolism. When the thyroid gland produces too much thyroid hormone, it can cause a range of symptoms, including weight loss, rapid heartbeat, anxiety, tremors, heat intolerance, sweating, and changes in menstrual patterns. In severe cases, thyrotoxicosis can lead to more serious complications, such as heart problems, eye problems, and even a life-threatening condition called thyroid storm. Thyrotoxicosis can be caused by a variety of factors, including Graves' disease, thyroiditis, and thyroid nodules. Treatment typically involves medications to reduce thyroid hormone production, radioactive iodine therapy, or surgery to remove part or all of the thyroid gland.
Graves' disease is an autoimmune disorder that affects the thyroid gland, a small gland located in the neck that produces hormones that regulate metabolism. In Graves' disease, the immune system mistakenly attacks the thyroid gland, causing it to produce excessive amounts of thyroid hormones, a condition known as hyperthyroidism. The symptoms of Graves' disease can vary widely and may include weight loss, rapid or irregular heartbeat, anxiety, tremors, heat intolerance, sweating, and bulging eyes (Graves' ophthalmopathy). The disease can also cause swelling of the thyroid gland, known as a goiter. Graves' disease is typically treated with medications that help to reduce the production of thyroid hormones, such as methimazole or propylthiouracil. In some cases, surgery or radioactive iodine therapy may be necessary to remove the overactive thyroid gland or destroy the gland's ability to produce hormones.
In the medical field, iodides refer to compounds that contain the element iodine. Iodine is an essential trace element that is required for the proper functioning of the thyroid gland, which is responsible for regulating metabolism in the body. There are several different types of iodides, including potassium iodide, sodium iodide, and calcium iodide. These compounds are often used in medical treatments to help prevent or treat thyroid disorders, such as hypothyroidism (an underactive thyroid) and hyperthyroidism (an overactive thyroid). Iodides can also be used to treat other conditions, such as radiation sickness, as well as to prevent the development of certain types of cancer, such as thyroid cancer and breast cancer. It is important to note that while iodides can be beneficial in certain medical situations, they can also have side effects and may interact with other medications. As such, it is important to use iodides under the guidance of a qualified healthcare professional.
Serum albumin is a type of protein that is found in the blood plasma of humans and other animals. It is the most abundant protein in the blood, accounting for about 50-60% of the total protein content. Serum albumin plays a number of important roles in the body, including maintaining the osmotic pressure of the blood, transporting hormones, fatty acids, and other molecules, and serving as a buffer to regulate pH. It is also an important indicator of liver function, as the liver is responsible for producing most of the serum albumin in the body. Abnormal levels of serum albumin can be an indication of liver disease, kidney disease, or other medical conditions.
Euthyroid sick syndrome (ESS) is a condition that occurs in patients who are critically ill and have an abnormal response to stress. It is characterized by a decrease in the production of thyroid hormones, despite normal levels of thyroid-stimulating hormone (TSH). This decrease in thyroid hormone production is thought to be caused by the body's response to stress, which can lead to a decrease in the production of thyroid-stimulating hormone-releasing hormone (TRH) and thyroid-stimulating hormone (TSH) from the hypothalamus and pituitary gland, respectively. ESS is most commonly seen in patients who are critically ill, such as those with sepsis, trauma, or major surgery. It is also seen in patients with certain medical conditions, such as cancer, heart failure, and chronic obstructive pulmonary disease (COPD). Symptoms of ESS can include fatigue, weakness, weight loss, and a slowed heart rate. Treatment for ESS typically involves treating the underlying cause of the illness and providing supportive care, such as fluid and electrolyte replacement, to help the body recover.
Norethandrolone is a synthetic estrogenic and androgenic steroid that is used in the medical field for various purposes. It is a derivative of the hormone norethisterone, which is a progestin. Norethandrolone is available in both oral and injectable forms and is commonly used in the treatment of conditions such as breast cancer, endometriosis, and uterine bleeding. It is also used in the treatment of menopausal symptoms, such as hot flashes and vaginal dryness. In addition, norethandrolone is sometimes used in the treatment of certain types of breast cancer in postmenopausal women. It is important to note that norethandrolone can have side effects, including mood changes, weight gain, and an increased risk of blood clots, and should only be used under the supervision of a healthcare professional.
Potassium iodide (KI) is a medication that is used to protect the thyroid gland from the harmful effects of radioactive iodine. It is typically prescribed to people who live in areas where there is a risk of exposure to radioactive iodine, such as after a nuclear accident or in areas where the soil is contaminated with radioactive iodine. KI works by saturating the thyroid gland with non-radioactive iodine, which prevents it from absorbing radioactive iodine. This helps to protect the thyroid gland from damage and reduces the risk of thyroid cancer. KI is usually taken as a pill, and the dose and duration of treatment depend on the level of radiation exposure and the individual's age and health. It is important to follow the instructions of a healthcare provider when taking KI to ensure that it is effective and safe.
Autoimmune thyroiditis, also known as Hashimoto's thyroiditis, is a type of thyroiditis that occurs when the immune system attacks the thyroid gland, leading to inflammation and damage to the gland. This condition is characterized by the production of antibodies against the thyroid gland, which can cause the gland to become enlarged and produce less thyroid hormone. Symptoms of autoimmune thyroiditis may include fatigue, weight gain, cold intolerance, constipation, dry skin, and depression. Treatment typically involves hormone replacement therapy with synthetic thyroid hormone to replace the hormone that the damaged thyroid gland is no longer producing.
Monoiodotyrosine (MIT) is a thyroid hormone intermediate that is produced when the thyroid gland converts the amino acid tyrosine into thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3). MIT is a precursor to T3 and is formed when one iodine atom is added to the tyrosine molecule. MIT is also used as a diagnostic tool in the medical field to measure the activity of the thyroid gland. A high level of MIT in the blood can indicate an overactive thyroid gland, while a low level can indicate an underactive thyroid gland. Additionally, MIT is used as a treatment for certain thyroid disorders, such as hyperthyroidism, by blocking the production of thyroid hormones in the gland.
Carbimazole is a medication used to treat hyperthyroidism, a condition in which the thyroid gland produces too much thyroid hormone. It works by inhibiting the production of thyroid hormones in the thyroid gland. Carbimazole is typically prescribed for patients with Graves' disease, a type of hyperthyroidism caused by an autoimmune disorder. It is usually taken orally, and the dosage may need to be adjusted periodically based on blood tests to monitor the patient's thyroid function. Side effects of carbimazole may include nausea, vomiting, diarrhea, headache, and skin rash. It is important to follow the dosage instructions provided by the healthcare provider and to report any side effects to the healthcare provider.
Diiodotyrosine, also known as DIT, is a thyroid hormone precursor that is formed from the amino acid tyrosine. It is produced in the thyroid gland and is converted into the thyroid hormones thyroxine (T4) and triiodothyronine (T3) through a series of enzymatic reactions. In the medical field, diiodotyrosine is used as a diagnostic tool to measure the function of the thyroid gland. A test called a DIT scan involves injecting a small amount of diiodotyrosine into the bloodstream and then using a special camera to track its uptake by the thyroid gland. The results of this test can help doctors diagnose conditions such as hyperthyroidism (an overactive thyroid gland) or hypothyroidism (an underactive thyroid gland). Diiodotyrosine is also used in the treatment of certain thyroid disorders. For example, it may be used to help regulate the production of thyroid hormones in people with hypothyroidism who do not respond well to standard treatment with thyroid hormone replacement therapy. It may also be used to treat certain types of thyroid cancer.
Perchlorates are a class of inorganic salts that contain the perchlorate ion (ClO4-). They are commonly used as oxidizing agents, rocket propellants, and as components in fireworks and pyrotechnics. In the medical field, perchlorates are used as a diagnostic tool to evaluate thyroid function. Specifically, perchlorate thyroid uptake tests are used to measure the ability of the thyroid gland to absorb and use iodine, which is an essential nutrient for the production of thyroid hormones. Perchlorates can also be used as a treatment for certain types of thyroid disorders, such as hyperthyroidism, by blocking the uptake of iodine by the thyroid gland and reducing the production of thyroid hormones. However, the use of perchlorates as a treatment is generally not recommended due to potential side effects and the availability of safer and more effective treatments.
Growth hormone (GH) is a peptide hormone produced by the anterior pituitary gland in the brain. It plays a crucial role in regulating growth and development in humans and other animals. GH stimulates the liver to produce insulin-like growth factor 1 (IGF-1), which promotes the growth of bones, muscles, and other tissues. In children, GH is essential for normal growth and development. It stimulates the growth plates in bones to lengthen, leading to increased height. In adults, GH is involved in maintaining muscle mass, bone density, and overall body composition. GH deficiency can lead to a variety of health problems, including short stature in children, decreased muscle mass and strength, increased body fat, and decreased bone density. GH replacement therapy is sometimes used to treat GH deficiency, particularly in children with growth disorders. In addition to its role in growth and development, GH has been studied for its potential therapeutic effects in a variety of conditions, including obesity, diabetes, and aging. However, the use of GH as a performance-enhancing drug is banned by most sports organizations due to its potential to increase muscle mass and strength.
Thyroiditis is a medical condition characterized by inflammation of the thyroid gland, which is a small gland located in the neck that produces hormones that regulate metabolism. There are several types of thyroiditis, including: 1. Subacute thyroiditis: This is a type of thyroiditis that is caused by a viral infection and is characterized by pain and swelling in the thyroid gland. 2. Hashimoto's thyroiditis: This is an autoimmune disorder in which the immune system attacks the thyroid gland, leading to inflammation and damage to the gland. 3. Postpartum thyroiditis: This is a type of thyroiditis that occurs in women after giving birth and is characterized by inflammation and swelling of the thyroid gland. 4. Thyroiditis associated with Graves' disease: This is a type of thyroiditis that occurs in people with Graves' disease, an autoimmune disorder that causes the thyroid gland to produce too much thyroid hormone. Symptoms of thyroiditis may include pain or tenderness in the neck, swelling of the thyroid gland, fatigue, weight gain or loss, and changes in heart rate or blood pressure. Treatment for thyroiditis depends on the underlying cause and may include medications to manage symptoms or treat the underlying condition, as well as lifestyle changes such as a healthy diet and regular exercise.
Serum Albumin, Radio-Iodinated is a radiopharmaceutical used in medical imaging to diagnose and monitor liver and kidney function. It is a modified form of serum albumin, a protein found in the blood, that has been labeled with radioactive iodine. The radioactive iodine allows the serum albumin to be detected by medical imaging equipment, such as a gamma camera or a PET scanner. When injected into the bloodstream, the serum albumin, radio-iodinated travels through the body and is taken up by the liver and kidneys. The amount of serum albumin that is taken up by these organs can be measured using medical imaging equipment, which can provide information about the function of the liver and kidneys. Serum albumin, radio-iodinated is often used to diagnose liver and kidney diseases, such as cirrhosis, hepatitis, and kidney failure. It can also be used to monitor the effectiveness of treatment for these conditions.
Thiouracil is a medication that is used to treat certain types of goiter, which is an enlargement of the thyroid gland. It works by reducing the production of thyroid hormones in the gland. Thiouracil is also used to treat hyperthyroidism, which is a condition in which the thyroid gland produces too much thyroid hormone. It is usually taken by mouth in the form of tablets. Side effects of thiouracil may include nausea, vomiting, diarrhea, and skin rash. It is important to follow the instructions of your healthcare provider when taking thiouracil.
Thyroxine deiodinase
Thyroxine-binding globulin
Thyroxine-binding proteins
Thyroxine 5-deiodinase
Reference ranges for blood tests
Thyroid function tests
Iodine in biology
Organoiodine chemistry
Chan-Lam coupling
Thyrotoxicosis factitia
Hermann Niemeyer
1914 in science
Thyroid
Electron transport chain
Thiocyanate
Thyrotoxic myopathy
Bovidae
Triiodothyronine
Polystyrene sulfonate
Victor Trikojus
George Barger
Once Upon a Time... Life
Lewis E. Braverman
Iodine deficiency
Congenital iodine deficiency syndrome
Levothyroxine
Amenorrhea
Tyropanoic acid
Pyridoxal phosphate
Aromatic amino acid
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Triiodothyronine4
- Thyroxine (T4) and triiodothyronine (T3) are the 2 biologically active thyroid hormones. (mayocliniclabs.com)
- Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status. (bvsalud.org)
- This review represents the conclusions on the clinical use of current routine TSH and TH ( thyroxine [T4] and triiodothyronine [T3]) assays, taking into account geographic differences in disease prevalence and clinical and laboratory practice among writing members. (bvsalud.org)
- Estimation of T4 (thyroxine) and T3 (triiodothyronine) is used to check for thyroid diseases. (orangehealth.in)
Serum10
- Serum thyroid-stimulating hormone (TSH) and thyroxine (T4) levels will be used to assess thyroid function and will provide population-based reference information on these hormone levels. (cdc.gov)
- The Access Total T4 assay is a paramagnetic particle, chemiluminescent, competitive binding enzyme immunoassay for the quantitative determination of total thyroxine (T4) in human serum, using the Access Immunoassay System. (cdc.gov)
- A sample was added to a reaction vessel with anti-thyroxine antibody, thyroxine-alkaline phosphatase conjugate, and paramagnetic particles coated with goat anti-mouse capture antibody and a stripping agent to dissociate all T4 from serum-binding proteins. (cdc.gov)
- And spread of some factors including serum during these anabolic interventions are associated suppression, L-Thyroxine for sale in the majority of patients. (showyou.com)
- order FRT4 / T4 (Thyroxine), Free, Serum. (mayocliniclabs.com)
- Evidence Central , evidence.unboundmedicine.com/evidence/view/EBMG/451238/all/Effect_of_thyroxine_therapy_on_serum_lipid_levels_in_subclinical_hypothyroidism. (unboundmedicine.com)
- Previous investigations have shown that the serum free thyroxine level of cats is affected by brief administration of food high or low in iodine content. (avmi.net)
- We have now measured serum free thyroxine levels in groups of cats fed relatively high or low iodine diets for much longer periods (5 months). (avmi.net)
- In contrast to our earlier findings, the chronic ingestion of relatively high or low iodine diets did not lead to statistically significant differences in serum free thyroxine levels. (avmi.net)
- A microplate chemiluminescence enzyme immunoassay (CLEIA) with high sensitivity, selectivity and reproducibility was developed for the determination of free thyroxine (FT4) in human serum. (ijbs.com)
Globulin2
- In the blood, T4 is either free (not bound) or protein-bound (primarily bound to thyroxine-binding globulin). (medscape.com)
- More than 99.9% of the T4 in blood is bound to carrier proteins, specially to thyroxine-binding globulin (TBG), and the free fraction of T4 (free T4, FT4) just accounts for ∼0.03% [ 1 ]. (ijbs.com)
Hypothyroidism3
- Free thyroxine (free T4) tests are used to help evaluate thyroid function and diagnose thyroid diseases, including hyperthyroidism and hypothyroidism, usually after discovering that the thyroid stimulating hormone (TSH) level is abnormal. (privatemdlabs.com)
- Therefore, when your doctor suspects any symptoms related to thyroid disease or Hypothyroidism, they may prescribe a Total T4 (Thyroxine) Test to determine the functioning of the thyroid gland. (redcliffelabs.com)
- T4 Test, also called Thyroxine Test, is used to assess thyroid functions, measure t4 levels and diagnose a condition that may affect the thyroid, including Hypothyroidism, Hyperthyroidism, and Disorders of the pituitary gland. (redcliffelabs.com)
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- Bound T4 is thyroxine that attaches or binds to certain proteins which prevent it from entering your tissues. (medlineplus.gov)
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- The test measures the level of thyroxine hormones & helps evaluate thyroid function. (redcliffelabs.com)
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- 2000. Assessing the role of ortho -substitution on polychlorinated biphenyl binding to transthyretin, a thyroxine transport protein. (cdc.gov)
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Synthetic2
- This is the most common synthetic form of thyroxine (thyroid hormone). (newbornscreening.info)
- Synthetic thyroxine is a form of the hormone that is naturally produced by the thyroid gland in the body. (365chemists.com)
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- Thyroxine (T4) is a hormone produced by the thyroid gland. (privatemdlabs.com)
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- What is a Thyroxine (T4) Test? (medlineplus.gov)
- A thyroxine test is a blood test that helps diagnose thyroid conditions. (medlineplus.gov)
- Why do I need a thyroxine test? (medlineplus.gov)
- What happens during a thyroxine test? (medlineplus.gov)
- In most cases, you don't need any special preparations for a thyroxine blood test. (medlineplus.gov)
- If your TSH test results are not normal or if you are suspected of having thyroid disease, you may be asked to get Thyroxine Test done. (redcliffelabs.com)
- When is the Thyroxine (T4) test recommended? (orangehealth.in)
- Why get the Thyroxine (T4) test? (orangehealth.in)
- The Thyroxine (T4) test is to measure: The thyroxine test analyses only the active form of the thyroid hormone, which is unbound and can directly enter the cells and affect them. (orangehealth.in)
- What is the cost of the Thyroxine (T4) test in Noida? (orangehealth.in)
- The cost of the Thyroxine (T4) test in Noida is Rs. (orangehealth.in)
- How often should I get tested for the Thyroxine (T4) test? (orangehealth.in)
- The Thyroxine (T4) test is prescribed by your doctor after completing the assessment of your conditions. (orangehealth.in)
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Total1
- Being a crucial thyroid hormone, Total T4 (Thyroxine) regulates metabolism, body temperature, and other body functions. (redcliffelabs.com)
Form2
- Free T4 is the active form of thyroxine hormone that enters your tissues where it's needed. (medlineplus.gov)
- Thyroxine, also called thyroxine T4, is the main form of thyroid hormone made by the thyroid gland. (orangehealth.in)
Body1
- To create a hyperthyroid condition, mature male Sprague--Dawley rats were given injections of thyroxine (dose range: 0.1 to 1 mg/kg body wt daily for 7 days). (cdc.gov)
Shown1
- The chemical structure of thyroxine is shown below. (medscape.com)
Specific1
- Thyroxine in the sample competed with the thyroxine-alkaline phosphatase conjugate for binding sites on a limited amount of specific anti-thyroxine antibody. (cdc.gov)
Anti-thyroxine2
- A sample was added to a reaction vessel with anti-thyroxine antibody, thyroxine-alkaline phosphatase conjugate, and paramagnetic particles coated with goat anti-mouse capture antibody and a stripping agent to dissociate all T4 from serum-binding proteins. (cdc.gov)
- Thyroxine in the sample competed with the thyroxine-alkaline phosphatase conjugate for binding sites on a limited amount of specific anti-thyroxine antibody. (cdc.gov)
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- Thyroxine is the generic name of the Thyronorm 100 mcg, and it is produced by Abbott Pharmaceuticals. (genericonlinemeds.com)
Hormone6
- Thyroxine, also known as T4, is a type of thyroid hormone. (medlineplus.gov)
- Free T4 is the active form of thyroxine hormone that enters your tissues where it's needed. (medlineplus.gov)
- In order to assess relationships between thyroid hormone status and findings on brain MRI, a subset of babies was recruited to a multi-centre randomised, placebo-controlled trial of levothyroxine (LT4) supplementation for babies born before 28 weeks' gestation (known as the TIPIT study, for Thyroxine supplementation In Preterm InfanTs ). (bvsalud.org)
- It is thyroglobulin's job to connect iodine and tyrosine to form basic thyroid hormone (thyroxine or T4). (wellnessresources.com)
- Hypothyroidism is a condition that, traditionally, is characterised by low levels of thyroid hormone (such as thyroxine), which in turn can lead to symptoms such as fatigue, mental sluggishness and low mood, weight gain, sensitivity to cold, cold hands and feet, dry skin, dry hair and thinning of the hair. (drbriffa.com)
- An underactive thyroid is typically associated with a thyroid-stimulating hormone (TSH) level above the reference range and a thyroxine (FT4) level that is below the reference range. (btf-thyroid.org)
Thyroid gland1
- Your doctor will prescribe levothyroxine, a synthetic version of the thyroxine produced by the thyroid gland. (btf-thyroid.org)
Concentrations1
- Among recipients of a placebo, babies in the lowest quartile of plasma -free thyroxine (FT4) concentrations had significantly higher apparent diffusion coefficient measurements in the posterior corpus callosum and streamlines that were shorter and less numerous in the right internal capsule . (bvsalud.org)
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- Natural desiccated thyroid is not necessarily for everyone, but my experience in practice tells me that, overall, it is more effective than levo-thyroxine (T4 alone) in the treatment of hypothyroidism, and often helps individuals who found that levo-thyroxine did little for them. (drbriffa.com)
Study3
- Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings in the TIPIT study. (bvsalud.org)
- In this study, hypothyroid individuals were treated, at separate times, with levo-thyroxine and desiccated thyroid (for 16 weeks each). (drbriffa.com)
- According to the report and summary of the study, desiccated thyroid did not result in improved quality of life compared with thyroxine alone, but did lead to 'modest' weight loss (3 lbs on average). (drbriffa.com)
Version2
- The prefix LEVO means the "left-hand" version of a molecule, and thyroxine is the biological term for the real T4. (stopthethyroidmadness.com)
- In just the same way that levothyroxine is the mirror-image or "left-handed" version of regular thyroxin, RT3, or Reverse T3, is the mirror-image or "left-handed" version of T3. (stopthethyroidmadness.com)