Adenocarcinoma, Follicular
Thyroid Gland
A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.
Carcinoma, Papillary
Thyroid Nodule
A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).
Biopsy, Fine-Needle
Carcinoma
Adenoma, Oxyphilic
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Galectin 3
A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.
Thyroid Hormones
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Immunohistochemistry
Receptors, Thyroid Hormone
Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.
Thyrotropin
A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.
Triiodothyronine
A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
Thyroxine
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Hypothyroidism
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Iodide Peroxidase
Thyroid Hormone Receptors beta
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Neoplasms
Goiter
Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Hyperthyroidism
Iodine
Neoplasms, Cystic, Mucinous, and Serous
Thyroiditis, Autoimmune
Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis.
Thyroid Hormone Receptors alpha
Graves Disease
A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
Neoplasms, Multiple Primary
Adenocarcinoma, Papillary
Iodine Radioisotopes
Carcinoma, Papillary, Follicular
Goiter, Nodular
Carcinoma, Medullary
A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)
Over-representation of a germline RET sequence variant in patients with sporadic medullary thyroid carcinoma and somatic RET codon 918 mutation. (1/4130)
The aetiology of sporadic medullary thyroid carcinoma is unknown. About 50% harbour a somatic mutation at codon 918 of RET (M918T). To investigate whether other RET sequence variants may be associated with or predispose to the development of sporadic medullary thyroid carcinoma, we analysed genomic DNA from the germline and corresponding tumour from 50 patients to identify RET sequence variants. In one patient, tumour DNA showed a novel somatic 12 bp in-frame deletion in exon 15. More interestingly, we found that the rare polymorphism at codon 836 (c.2439C > T; S836S) occurred at a significantly higher frequency than that in control individuals without sporadic medullary thyroid carcinoma (Fisher's exact test, P = 0.03). Further, among the nine evaluable cases with germline c.2439C/T, eight also had the somatic M918T mutation in MTC DNA which was more frequent than in patients with the more common c.2439C/C (89% vs 40%, respectively; Fisher's exact test, P = 0.01). These findings suggest that the rare sequence variant at codon 836 may somehow play a role in the genesis of sporadic medullary thyroid carcinoma. (+info)Medullary thyroid carcinoma with multiple hepatic metastases: treatment with transcatheter arterial embolization and percutaneous ethanol injection. (2/4130)
A 54-year-old man with medullary thyroid carcinoma in the thyroid gland was unable to undergo total thyroidectomy because the tumor had invaded the mediastinum. Radiation therapy and chemotherapy were given. Seven years later, intractable diarrhea and abdominal pain appeared, and computed tomography demonstrated hypervascular tumors in the thyroid gland and in the liver. The tumors were successfully treated with percutaneous ethanol injection to a lesion in the thyroid gland and transcatheter arterial embolization followed by percutaneous ethanol injection to tumors in the liver. Transcatheter arterial embolization and percutaneous ethanol injection may be valuable in treating medullary thyroid carcinoma. (+info)Epithelial thyroid tumors in cows. (3/4130)
From 1964 to 1973, 370 tumors were collected from cows of unknown age. Ten (2.7%) of these were primary thyroid tumors. Three were malignant. The benign tumors were solitary encapsulated adenomas in the parenchyma with more or less defined trabeculae, tubular, and microfollicular pattern. One of the malignant tumors was a cystic papillary adenocarcinoma, and two were small cell carcinomas consisting of small, sometimes binuclear, pleomorphic cells. (+info)Overexpression of fibroblast growth factor receptor 3 in a human thyroid carcinoma cell line results in overgrowth of the confluent cultures. (4/4130)
Recent reports indicate that a gain-of-function mutation in fibroblast growth factor receptor 3 (FGFR-3) inhibits cell growth in the cartilaginous growth plates. These results suggest that FGFR-3 may be the receptor transducing growth inhibitory signals. Using reverse transcription-PCR we examined seven papillary thyroid carcinomas to determine FGFR-3 expression. Six out of the seven papillary carcinomas expressed FGFR-3. To clarify the role of FGFR-3 in thyroid carcinoma, FGFR-3 was overexpressed in an established human papillary thyroid carcinoma cell line. High levels of FGFR-3 protein were identified in cells stably transfected with the vector containing FGFR-3 cDNA. The specific binding of 125I-FGF-2 of these cells was threefold higher than that of control cells. Growth rates of cells overexpressing FGFR-3 were similar to those of control cells. However, cells overexpressing FGFR-3 continued to grow beyond the density at which control cells stopped proliferating. These results suggest that FGFR-3 in thyroid carcinoma is not involved strongly in the cell proliferation mechanism but may contribute to the malignant extension of some of the carcinomas by modifying cell contact signaling. (+info)Psychosocial impact of genetic testing in familial medullary-thyroid carcinoma: a multicentric pilot-evaluation. (5/4130)
BACKGROUND: Many crucial problems are associated with the diagnosis of inherited cancer susceptibility. One of the most important is related to the psychosocial consequences of the knowledge by the patients and their relatives of their own genetical status. Little data are available in the literature, mainly from studies including small numbers of selected and motivated patients. PATIENTS AND METHODS: From January till December 1997, we studied the psychometric and quality of life parameters of 77 subjects followed in two French specialized centers. These subjects had been treated for either sporadic or familial or were at risk for medullary thyroid carcinoma. All patients had previously attended genetic counselling with detection of germline Ret-mutations, were informed on their own genetic risk, had good short-term prognosis and performance status and did not receive recent cancer treatment. Each patient was invited to answer two questionnaires, the hospital anxiety and depression scale (HADS) and the subjective quality of life profile (SQLP). RESULTS: We report herein the descriptive results of this study (HADS and SQLP scores and distributions) and describe the individual clinical covariates that might explain the observed differences between subgroups of individuals. Although psychometric scores appeared similar in these subgroups, quality of life scores were lower in Ret-mutation carriers. Genetically-predisposed patients were less satisfied and expressed more expectations for favourable change in their quality of life. CONCLUSION: This finding suggests a high level of frustration and latent unsatisfaction related either to the management of the genetic information given by the clinicians and its psychosocial consequences or simply to the knowledge of the genetic risk of cancer. Further studies on the individual consequences of genetic testing, information delivery and when necessary psychotherapeutic interventions, are needed to insure the quality of presymptomatic genetic testing in this field of oncology. (+info)A new rapid technique for the fixation of thyroid gland surgical specimens. (6/4130)
One of the main diagnostic problems in thyroid pathology is to distinguish between follicular adenoma and follicular carcinoma. Thorough sampling of the nodule's capsule is recommended in order to identify capsular invasion. However, during the hardening of the tissue, by the usual fixatives the capsule shrinks and rolls downwards and sometimes the capsule separates from the remaining tissue. The present work evaluates the use of "Lymph Node Revealing Solution" (LNRS) for the rapid fixation (2h) of different thyroid lesions as compared to that of formalin. Fifty-one unselected consecutive cases of thyroid nodules, which included various benign and malignant lesions, were examined. Each specimen was cut in two equal parts; one was fixed in LNRS, the other in formalin. Fixation in LNRS for 2 hours gave adequate results in sectioning and staining of the tissue, and excellent immunostains. Its advantage over formalin is the conservation of the natural relationship between the capsule and the rest of the tissue, on the same plane, as well as the short time required for the final diagnosis. (+info)Overexpression of c-Ras in hyperplasia and adenomas of the feline thyroid gland: an immunohistochemical analysis of 34 cases. (7/4130)
Formalin-fixed, paraffin-embedded thyroid glands from 18 cats diagnosed with hyperthyroidism were evaluated immunohistochemically for overexpression of the products of oncogenes c-ras and bcl2 and the tumor suppressor gene p53. Fourteen thyroid glands from euthyroid cats without histologically detectable thyroid lesions were examined similarly as controls. Results from these investigations showed that all cases of nodular follicular hyperplasia/adenomas stained positively for overexpression of c-Ras protein using a mouse monoclonal anti-human pan-Ras antibody. The most intensely positively staining regions were in luminal cells surrounding abortive follicles. Subjacent thyroid and parathyroid glands from euthyroid cats did not stain immunohistochemically for pan-Ras. There was no detectable staining for either Bc12 or p53 in any of the cats. These results indicated that overexpression of c-ras was highly associated with areas of nodular follicular hyperplasia/adenomas of feline thyroid glands, and mutations in this oncogene may play a role in the etiopathogenesis of hyperthyroidism in cats. (+info)Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53. (8/4130)
Differentiated thyroid carcinomas (in contrast to the rarer anaplastic form) are unusual among human cancers in displaying a remarkably low frequency of p53 mutation and appear to retain wild-type (wt) p53 function as assessed by the response of derived cell lines to DNA damage. Using one such cell line, K1, we have tested the effect of experimental abrogation of p53 function by generating matched sub-clones stably expressing either a neo control gene, a dominant-negative mutant p53 (143ala) or human papilloma virus protein HPV16 E6. Loss of p53 function in the latter two groups was confirmed by abolition of p53-dependent 'stress' responses including induction of the cyclin/CDK inhibitor p21WAF1 and G1/S arrest following DNA-damage. In contrast, no change was detected in the phenotype of 'unstressed' clones, with respect to any of the following parameters: proliferation rate in monolayer, serum-dependence for proliferation or survival, tumorigenicity, cellular morphology, or tissue-specific differentiation markers. The K1 line therefore represents a 'neutral' background with respect to p53 function, permitting the derivation of functionally p53 + or - clones which are not only iso-genic but also iso-phenotypic. Such a panel should be an ideal tool with which to test the p53-dependence of cellular stress responses, particularly the sensitivity to potential therapeutic agents, free from the confounding additional phenotypic differences which usually accompany loss of p53 function. The results also further support the hypothesis that p53 mutation alone is not sufficient to drive progression of thyroid cancer to the aggressive anaplastic form. (+info)Altered gene expression profiles by sodium/iodide symporter gene transfection in a human anaplastic thyroid carcinoma cell line...
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Thyroid neoplasm
... is a neoplasm or tumor of the thyroid. It can be a benign tumor such as thyroid adenoma, or it can be a ... Thyroid adenoma is a benign neoplasm of the thyroid. Thyroid nodules are very common and around 80 percent of adults will have ... Thyroid nodules are a major presentation of thyroid neoplasms, and are diagnosed by ultrasound guided fine needle aspiration ( ... Other thyroid malignancies include thyroid lymphoma, various types of thyroid sarcoma, smooth muscle tumors, teratoma, squamous ...
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features
... (NIFTP) is an indolent thyroid tumor that was ... A noninvasive neoplasm that arises from the thyroid follicular cells (cells that normally make thyroid hormone), showing a ... Abbreviations: NIFTP: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features EFVPTC: Encapsulated ... Definition of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): ...
Oncogene
Mitchell RS, Kumar V, Abbas AK, Fausto N (2007). "Chapter 20 - Neoplasms of the Thyroid". Robbins Basic Pathology (8th ed.). ...
Hürthle cell
Erickson, Lori A. "Hurthle Cell Thyroid Neoplasms." Atlas of Endocrine Pathology. Springer New York, 2014. 63-66. Hürthle, Karl ... Hürthle cell is used only to indicate cells of thyroid follicular origin. Hürthle cell neoplasms can be separated into Hürthle ... of all differentiated thyroid cancers. Oncocytes in the thyroid are often called Hürthle cells. Although the terms oncocyte, ... formerly considered a subtype of follicular thyroid cancer). This version is a relatively rare form of differentiated thyroid ...
Project 4.1
Hempelmann, L H (1968). "Risk of thyroid neoplasms after irradiation in childhood. Studies of populations exposed to radiation ... Children began to disproportionately develop thyroid cancer (due to exposure to radioiodines), and almost a third of those ... exposed developed neoplasms by 1974.[unreliable medical source?] James Reeves to Frank D. Peel, "Establishment of Program 4 and ...
Mammary secretory carcinoma
"Overview of the 2022 WHO Classification of Thyroid Neoplasms". Endocrine Pathology. 33 (1): 27-63. doi:10.1007/s12022-022-09707 ... thyroid gland (now termed salivary gland-type carcinoma of the thyroid), or skin (now termed secretory carcinoma of the skin or ... salivary gland-type carcinomas of the thyroid, and secretory carcinoma of the skin. This translocation is the sole genetic ... "Clinicopathologic and molecular characterization of NTRK-rearranged thyroid carcinoma (NRTC)". Modern Pathology. 33 (11): 2186- ...
Secretory carcinoma
"Overview of the 2022 WHO Classification of Thyroid Neoplasms". Endocrine Pathology. 33 (1): 27-63. doi:10.1007/s12022-022-09707 ... In a review of 11 cases, salivary gland-type carcinomas of the thyroid were diagnosed in adult females (9 cases) and males (2 ... Chambers M, Nosé V, Sadow PM, Tafe LJ, Kerr DA (March 2021). "Salivary-Like Tumors of the Thyroid: A Comprehensive Review of ... All cases were treated by thyroidectomy (removal of the thyroid gland) plus radiotherapy in 6 cases and/or chemotherapy in 3 ...
ETV6-NTRK3 gene fusion
"Overview of the 2022 WHO Classification of Thyroid Neoplasms". Endocrine Pathology. 33 (1): 27-63. doi:10.1007/s12022-022-09707 ... and radiation-induced papillary thyroid carcinoma. Because cancers associated with the expression of the ETV6-NTRK3 fusion ... salivary gland-type carcinoma of the thyroid, secretory carcinoma of the skin, congenital fibrosarcoma, congenital mesoblastic ...
Invasive cribriform carcinoma of the breast
"Overview of the 2022 WHO Classification of Thyroid Neoplasms". Endocrine Pathology. 33 (1): 27-63. doi:10.1007/s12022-022-09707 ... thyroid gland (termed cribriform-morular thyroid carcinoma), colon (termed cribriform colon cancer), and lung (termed ...
Tafazzin
... papillary thyroid carcinoma, non-small cell lung cancer, glioma, gastric cancer, thyroid neoplasms, and rectal cancer. It is ... papillary thyroid carcinoma and non-small cell lung cancer, glioma, gastric cancer, thyroid neoplasms, and rectal cancer. Barth ... In thyroid neoplasm, TAFAZZIN allows follicular adenomas to be distinguished from follicular carcinomas, while in cervical ... TAFAZZIN overexpression has been linked to rectal cancer, prostate cancer, thyroid neoplasm, and cervical cancer. In a study of ...
David Velázquez Fernández
2009) Information theoretical methods to deconvolute genetic regulatory networks applied to thyroid neoplasms. (2009) Análisis ... Accuracy of centinel node in papillary thyroid carcinoma (2001) Quality of life in bariatric surgery (2002) Utilidad de la ...
N-alpha-acetyltransferase 10
"Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms". Thyroid. 15 (10): 1131-6 ...
Stt3a, catalytic subunit of the oligosaccharyltransferase complex
... putative markers for characterization of follicular thyroid neoplasms from fine-needle aspirates". Laryngoscope. 121 (5): 983-9 ... ARG2 and FAM129A are not useful in diagnosing thyroid follicular tumors". Mod. Pathol. 25 (4): 537-47. doi:10.1038/modpathol. ...
NAA15
"Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms". Thyroid. 15 (10): 1131-6 ... Fluge Ø, Bruland O, Akslen LA, Varhaug JE, Lillehaug JR (2002). "NATH, a novel gene overexpressed in papillary thyroid ...
Kate Pragnell
Pragnell died on 19 November 1905 at 39 Brompton Square, from a thyroid neoplasm. She bequeathed her business to Alice Stewart ...
Hyalinizing trabecular adenoma
A challenging neoplasm of the thyroid". Endocrine Practice. 17 (6): e140-3. doi:10.4158/EP11138.CR. PMID 21940281. v t e ( ... Hyalinizing trabecular adenoma (or Hyalinizing trabecular adenoma) is a subtype of thyroid adenoma. Ünlütürk, U; Karaveli, G; ... Thyroid tumor, All stub articles, Medical sign stubs). ...
Squamous-cell thyroid carcinoma
... is rare malignant neoplasm of thyroid gland which shows tumor cells with distinct squamous ... The incidence of SCTC is less than 1% out of thyroid malignancies. Squamous epithelial cells are not found in normal thyroid, ... Often SCTC is diagnosed in one of the thyroid lobes, but not in the pyramidal lobe. Another possible way of SCTC development ... MI Syed; M Stewart; S Syed; S Dahill; C Adams; DR Mclellan; LJ Clark (2011). "Squamous cell carcinoma of the thyroid gland: ...
Follicular thyroid cancer
If fine needle aspiration cytology (FNAC) suggests follicular neoplasm, thyroid lobectomy should be performed to establish the ... Thyroid follicular cells are the thyroid cells responsible for the production and secretion of thyroid hormones. Approximately ... Thyroid and Parathyroid Cancers Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer The ... Follicular thyroid cancer accounts for 15% of thyroid cancer and occurs more commonly in women over 50 years of age. ...
Thyroid adenoma
A challenging neoplasm of the thyroid". Endocrine Practice. 17 (6): e140-3. doi:10.4158/EP11138.CR. PMID 21940281. Carlé, Allan ... emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules By Daniel J Kelley and Arlen D Meyers. ... A thyroid adenoma is a benign tumor of the thyroid gland, that may be inactive or active (functioning autonomously) as a toxic ... A thyroid adenoma is distinguished from a multinodular goiter of the thyroid in that an adenoma is typically solitary, and is a ...
Poorly differentiated thyroid cancer
Poorly differentiated thyroid carcinoma is malignant neoplasm of follicular cell origin showing intermediate histopathological ... v t e (Articles with short description, Short description matches Wikidata, Thyroid cancer, All stub articles, Oncology stubs) ... "Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic ... patterns between differentiated and undifferentiated thyroid cancers. Presence of small cells with round nuclei and scant ...
Thyroid cancer
Newly reclassified variant: noninvasive follicular thyroid neoplasm with papillary-like nuclear features is considered an ... Stage M1 thyroid cancer Stage N1a thyroid cancer Stage N1b thyroid cancer Stage T1a thyroid cancer Stage T1b thyroid cancer ... The four main types are papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and anaplastic thyroid ... T2 thyroid cancer Stage T3 thyroid cancer Stage T4a thyroid cancer Stage T4b thyroid cancer Detection of differentiated thyroid ...
Radiation effects from the Fukushima Daiichi nuclear disaster
Increased risk for thyroid neoplasm remains elevated for at least 40 years after exposure. Potassium iodide tablets prevent ... None had thyroid cancer.[citation needed] Fukushima Medical University gives the number of children diagnosed with thyroid ... Persons exposed to releases of I-131 from any source have a higher risk for developing thyroid cancer or thyroid disease, or ... Ultrasonographic detectable thyroid nodules and cysts are extremely common and can be found at a frequency of up to 67% in ...
Multiple endocrine neoplasia
Other endocrine and non-endocrine neoplasms including adrenocortical and thyroid tumors, visceral and cutaneous lipomas, ... Medullary Thyroid Ca MEN IIb (1P, 2Ms) - Pheochromocytoma, Medullary Thyroid Ca, Marfanoid habitus/mucosal neuroma MEN1 gene ... of patients with MEN1 and gastrinoma FMTC = familial medullary thyroid cancer MEN 2B is sometimes known as MEN 3 and the ... described medullary (solid) thyroid carcinoma.[citation needed] In 1961 Sipple described a combination of a pheochromocytoma, ...
NIFTP
... one of the Coloured Book protocols Noninvasive follicular thyroid neoplasm with papillary-like nuclear features - a tumour ... previously classified as papillary thyroid carcinoma This disambiguation page lists articles associated with the title NIFTP. ...
Downwinders
Several severe adverse health effects, such as an increased incidence of cancers, thyroid diseases, CNS neoplasms, and possibly ... and thyroid tissues as the most radiosensitive among women. For example, the FGR 13 has estimated that the ratio of thyroid ... Estimated Exposures and Thyroid Doses Received by the American People from Iodine-131 in Fallout Following Nevada Atmospheric ... The Hanford Thyroid Disease Study, an epidemiologic study of the relationship between estimated exposure doses to radioiodine ...
Squamous cell carcinoma
... system lists a number of morphological subtypes and variants of malignant squamous cell neoplasms, including: Papillary thyroid ... A type of lung cancer Squamous-cell thyroid carcinoma: A type of thyroid cancer Esophageal squamous-cell carcinoma: A type of ... Primary squamous-cell thyroid carcinoma shows an aggressive biological phenotype resulting in poor prognosis for patients. ... Berman JJ (November 2004). "Tumor taxonomy for the developmental lineage classification of neoplasms". BMC Cancer. 4 (1): 88. ...
Nuclear groove
It can be present in: Thyroid neoplasms: It is a characteristic feature of papillary thyroid carcinoma, but has also been seen ... in other types of thyroid neoplasms, as well as in non-neoplastic thyroid lesions. Ovarian tumors including Brenner tumors, ... Breast carcinomas Vaginal, cervical and/or endometrial neoplasms Papillary neoplasms of several organs: papillary transitional ... Pathogenesis and Diagnostic Significance of Nuclear Grooves in Thyroid and Other Sites". International Journal of Surgical ...
Hürthle cell neoplasm
... is a rare tumor of the thyroid, typically seen in women between the ages of 70 and 80 years old. When ... The thyroid gland is responsible for producing the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Patients with ... "Thyroid Cancer: About Thyroid Cancer , Memorial Sloan Kettering Cancer Center". www.mskcc.org. Retrieved 2015-11-23. Ristevska ... Some patients may only have half of their thyroid removed, this is known as a thyroid lobectomy. Another treatment option ...
Iodine-131
"Malignant and benign neoplasms of the thyroid in patients treated for hyperthyroidism: a report of the cooperative ... For example, children treated with moderate dose of 131I for thyroid adenomas had a detectable increase in thyroid cancer, but ... This occurs because when the radioactive iodine destroys the thyroid cells, they can release thyroid hormone into the blood ... and will also accumulate in the thyroid. As it decays, it may cause damage to the thyroid. The primary risk from exposure to ...
Yuri Nikiforov (scientist)
"Colloid-Rich" follicular neoplasm/suspicious for follicular neoplasm thyroid fine-needle aspiration specimens: Cytologic, ... Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology ... Noninvasive follicular thyroid neoplasms cause little risk for patients Dr. Nikiforov on Reclassifying Subtype of Thyroid ... The patients still undergo surgery, in which their thyroid tumors are removed, typically with half, but not all, of the thyroid ...
List of cardiology mnemonics
Pirates:p. 3 Pulmonary: PE, COPD Iatrogenic Rheumatic heart: mitral regurgitation Atherosclerotic: MI, CAD Thyroid: ... Infections Acute renal failure Cardiac infarction Rheumatic fever Injury Neoplasms Dressler's syndrome PericarditiS:p. 34 PR ...
List of diseases (C)
... type 2 Cutis marmorata telangiectatica congenita Cutis verticis gyrata mental deficiency Cutis verticis gyrata thyroid aplasia ... Carrington syndrome Cartilage hair hypoplasia like syndrome Cartilage-hair hypoplasia Cartilaginous neoplasms Cartwright-Nelson ... hypoxia Cerebral malformations hypertrichosis claw hands Cerebral palsy Cerebral thrombosis Cerebral ventricle neoplasms ... Choriocarcinoma Chorioretinitis Chorioretinopathy dominant form microcephaly Choroid plexus cyst Choroid plexus neoplasms ...
Laboratory rat
Comparison of Neoplasms in Six Sources of Rats Diamond JM (January 2006). Collapse: How Societies Choose to Fail or Succeed. ... and C-cell adenomas/adenocarcinomas of the thyroid gland and tumors of the haemopoietic system in males. Second, Lewis rats are ... The Lewis rat suffers from several spontaneous pathologies: first, they can suffer from high incidences of neoplasms, with the ... A 1972 study compared neoplasms in Sprague Dawley rats from six different commercial suppliers and found highly significant ...
Carney complex
Thyroid and pancreas cancer may also occur. Although J Aidan Carney also described Carney's triad it is entirely different. ... Melanocytic nevi and neoplasms, Syndromes affecting the skin, Syndromes affecting the heart, Syndromes with tumors). ... Bano G, Hodgson S (2016). "Diagnosis and Management of Hereditary Thyroid Cancer". Recent Results Cancer Res. Recent Results in ... "Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association". J Clin Endocrinol Metab. 96 (11): ...
Index of biochemistry articles
... neoplasm protein - Nernst equation - nerve - nerve growth factor - nerve growth factor receptor - nerve tissue protein - nerve ... thyroid hormone receptor - thyrotropin - thyrotropin receptor - thyrotropin-releasing hormone receptor - thyroxine - timeline ...
Craniopharyngioma
The immune system, thyroid levels, growth hormone levels, and testosterone levels can be compromised from craniopharygioma. All ... usually suprasellar neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch. Rathke's ...
Cancer
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... "Avoiding the 'C' Word for Low-Risk Thyroid Cancer". Medscape. Retrieved 13 April 2020. "The C word: how we react to cancer ... Autopsy studies in Europe and Asia showed that up to 36% of people have undiagnosed and apparently harmless thyroid cancer at ... and thyroid cancer as well as other cancer types. The efficacy of chemotherapy depends on the type of cancer and the stage. In ...
Intraparenchymal hemorrhage
Hemorrhagic neoplasms are more complex, heterogeneous bleeds often with associated edema. These hemorrhages are related to ... Glioblastomas are the most common primary malignancies to hemorrhage while thyroid, renal cell carcinoma, melanoma, and lung ... of consciousness Hypertension Arteriovenous malformation Aneurysm rupture Cerebral amyloid angiopathy Intracranial neoplasm ...
Hyperinsulinemia
Neoplasm Carbohydrate malabsorption Pancreatic cancer Polycystic ovary syndrome (PCOS) Trans fats Since hyperinsulinemia and ... possibly connected to an underactive thyroid) Obesity and hyperinsulinemia have some links with some types of cancer Fasting ...
Downregulation and upregulation
Such mutations and epigenetic alterations can give rise to cancer (see malignant neoplasms).[verification needed] Investigation ... of thyroid cancers, 40-90% of colorectal cancers and 50% of brain cancers.[citation needed] Similarly, epigenetic ...
Radiation therapy
Examples are the infusion of metaiodobenzylguanidine (MIBG) to treat neuroblastoma, of oral iodine-131 to treat thyroid cancer ... Hypopituitarism commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head ... In contrast, adrenocorticotrophic hormone (ACTH) and thyroid stimulating hormone (TSH) deficiencies are the least common among ... thyroid dysfunction, and pituitary axis dysfunction. Modern radiation therapy aims to reduce side effects to a minimum and to ...
List of skin conditions
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... Thyroid acropachy Eosinophilic cutaneous conditions encompass a wide variety of diseases that are characterized histologically ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
Mucoepidermoid carcinoma
"Salivary Gland Neoplasms". Medscape.{{cite web}}: CS1 maint: multiple names: authors list (link) Updated: Jan 13, 2021}} ... Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, and thyroid gland. Mucicarmine ... "Primary mucoepidermoid carcinoma and sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid gland: a report of ...
Extraskeletal myxoid chondrosarcoma
EMC shows the smallest morphological variation between the tumors among all myxoid soft tissue neoplasms. The myxoid matrix has ... in some of the thyroid papillary carcinomas. Recent evidence demonstrates that tumors with these various translocations have ... Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs ... Articles with short description, Short description matches Wikidata, Neoplasms, Oncology). ...
Idiopathic orbital inflammatory disease
Its diagnosis is of exclusion once neoplasm, primary infection and systemic disorders have been ruled out. Once diagnosed, it ... A differential diagnosis includes lymphoproliferative lesions, thyroid ophthalmopathy, IgG4-related ophthalmic disease, ... Its former name, orbital pseudotumor, is derived due to resemblance to a neoplasm. However, histologically it is characterized ... most common cause of exophthalmos following Grave's orbitopathy and the third most common orbital disorder following thyroid ...
MALT lymphoma
ISBN 0-7817-5007-5. Frequency of lymphoid neoplasms. (Source: Modified from WHO Blue Book on Tumour of Hematopoietic and ... and MALT lymphoma of the salivary gland and the thyroid). Owing to the causal relationship between H. pylori infection and MALT ...
Glossary of communication disorders
Laryngeal neoplasms Abnormal growths in the larynx (voice box) that can be cancerous or noncancerous. Laryngeal nodules ... This surgery is named for its proximity to the thyroid gland. Tinnitus Sensation of a ringing, roaring, or buzzing sound in the ... thyroid problems, or trauma to the larynx (voice box). Hyper neurotic diafragma contractions The hiccups Hypogeusia Diminished ... a window in the thyroid cartilage is created and an implant is inserted into the para-glottic space via an open approach. ...
List of diseases (T)
... dysplasia Thymoma Thymus neoplasm Thyrocerebrorenal syndrome Thyroglossal tract cyst Thyroid agenesis Thyroid cancer Thyroid ... carcinoma, follicular Thyroid carcinoma, papillary (TPC) Thyroid hormone plasma membrane transport defect Thyroid, renal and ... Temtamy-Shalash syndrome TEN Ter Haar-Hamel-Hendricks syndrome Ter Haar syndrome Teratocarcinosarcoma Teratoma Testes neoplasm ... syndrome Tolosa-Hunt syndrome Toluene antenatal infection Tomaculous neuropathy Tome-Brune-Fardeau syndrome Tongue neoplasm ...
Epithelioid sarcoma
... thyroid hormone receptor beta, and nuclear receptor coactivator 1, among others. Cyclin D and CDKs promote cell cycle ... a distinctive aggressive neoplasm showing rhabdoid features. Clinicopathologic, immunohistochemical, and ultrastructural study ...
List of MeSH codes (D12.776)
... thyroid hormone MeSH D12.776.624.664.700.830.500 - thyroid hormone receptors alpha MeSH D12.776.624.664.700.830.750 - thyroid ... neoplasm MeSH D12.776.377.715.548.114.248 - antibodies, phospho-specific MeSH D12.776.377.715.548.114.252 - antibodies, ... thyroid-stimulating MeSH D12.776.377.715.548.114.323.480.500 - long-acting thyroid stimulator MeSH D12.776.377.715.548.114. ... long-acting thyroid stimulator MeSH D12.776.377.715.548.114.619.393.570 - muromonab-cd3 MeSH D12.776.377.715.548.114.619.393. ...
Leo K. Bustad
Marks, Sidney; George, Lynn A.; Bustad, Leo K. (1957). "Fibrosarcoma involving the thyroid gland of a sheep given I131 daily". ... "Studies on the prevalence of type C virus associated with gibbon hematopoietic neoplasms". Bibliotheca Haematologica. ... Bustad, L. K.; Marks, S.; George, L. A.; Seigneur, L. J. (1957). "Thyroid Adenomas in Sheep administered Iodine-131 Daily". ...
Mir-25 microRNA precursor family
"Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb ... MicroRNA expression pattern in intraductal papillary mucinous neoplasm]". The Korean Journal of Gastroenterology = Taehan ...
Thymidine kinase in clinical chemistry
"Increased activities of thymidylate synthetase and thymidine kinase in human thyroid tumors". Thyroid. 1 (4): 347-51. doi: ... Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... in thyroid tumors in leukemia and in breast cancer. Therapy that influences the rate of cell proliferation influences the TK ... "Biochemical measure of the volume doubling time of human pulmonary neoplasms". Cancer. 55 (7): 1530-5. doi:10.1002/1097-0142( ...
Hydroquinone
This conclusion was reached based on the extent of absorption in humans and the incidence of neoplasms in rats in several ... studies where adult rats were found to have increased rates of tumours, including thyroid follicular cell hyperplasias, ...
Browsing EB95 by Subject "Thyroid Neoplasms"
Malignant neoplasms of thyroid and other endocrine glands - ICD-10 Codes- Codify by AAPC
The Icd-10 code range for Malignant neoplasms of thyroid and other endocrine glands C73-C75 is medical classification list by ... Malignant neoplasms of thyroid and other endocrine glands contains ICD-10 codes for Malignant neoplasm of thyroid gland, ... Malignant neoplasms of thyroid and other endocrine glands ICD-10-CM Code range C73-C75. The ICD-10 code range for Malignant ... Malignant neoplasm of adrenal gland, Malignant neoplasm of other endocrine glands and related structures ...
Follicular Neoplasm in a 19yr Old Female - Thyroid Disease ManagerThyroid Disease Manager
MORE STRANGE THYROID TESTS- 2 March 2015. March 2, 2015. *SUPPRESSED TSH WITHOUT CLEAR CAUSE? TREATMENT? 10Jan2015. January 12 ... Contact Thyroid Manager. By letter. Endocrine Education, Inc.. 5490 South Shore Drive, N1. Att: Samuel Refetoff, President ... Clinically it is a thyroid cyst replacing whole of the left lobe. no history in family, exposureto radiation etc. is present. ... TFTs are normal.FNAC has shown follicular neoplasm. I plan to take her up for hemithyroidectomy proceed sos ...
Results of search for 'su:{Thyroid neoplasms}' › WHO HQ Library catalog
Histological typing of thyroid tumours / Chr. Hedinger, in collaboration with E. D. Williams and L. H. Sobin. by Hedinger, ... Histological typing of thyroid tumours / Chr. Hedinger, in collaboration with L. H. Sobin. by Hedinger, Christoph Ernst , Sobin ... by International Thyroid Congress (9th: 1985: São Paulo, Brazil) , Medeiros-Neto, Geraldo A , Gaitan, Eduardo. ... Treatment of thyroid cancer in childhood : proceedings of a workshop held September 10-11, 1992, at the National Institutes of ...
Thyroid Cancer | Thyroid Cancer Treatment | MedlinePlus
There are several thyroid cancer types with different treatments. Discover options available. ... Your thyroid is a butterfly-shaped gland in your neck. ... ClinicalTrials.gov: Thyroid Neoplasms (National Institutes of ... Thyroid Hormone Treatment (American Thyroid Association) Also in Spanish * Thyroid Surgery (American Thyroid Association) Also ... What is thyroid cancer?. Thyroid cancer is a cancer that starts in the tissues of the thyroid. Your thyroid is a small, ...
IMSEAR at SEARO: Spectrum of thyroid neoplasms: A one year study at tertiary referral center
Background: Thyroid cancer accounts for approximately 1% of total cancer cases Thyroid neoplasms are most common malignant ... Sireesha Annapoorna, Triveni B., Sai Mallikarjun, K Srilaxmi.. Spectrum of thyroid neoplasms: A one year study at tertiary ... Spectrum of thyroid neoplasms: A one year study at tertiary referral center. ... Follicular adenoma was the most common benign neoplasm We have encountered almost the entire spectrum of thyroid neoplasms ...
Hurthle Cell Carcinoma (Oncocytic Carcinoma) Medication: Thyroid hormones
... few institutions have extensive experience with Hürthle cell neoplasms. ... Hürthle cell cancer accounts for only about 3-10% of all differentiated thyroid cancers; therefore, ... Hürthle cell carcinoma of the thyroid gland is an unusual and relatively rare type of differentiated thyroid cancer. ... The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016 Jan ...
Regulations - WTC Health Program
Malignant neoplasm of the thyroid.. * Malignant neoplasms of the blood and lymphoid tissues (including, but not limited to, ... Malignant neoplasm of the urinary bladder.. * Malignant neoplasm of the kidney.. * Malignant neoplasms of the renal pelvis; ... Malignant neoplasms of the liver and intrahepatic bile duct.. * Malignant neoplasms of the retroperitoneum and peritoneum; ... Malignant neoplasms of the trachea; bronchus and lung; heart, mediastinum and pleura; and other ill-defined sites in the ...
Browsing Governing bodies by Subject
Use of color Doppler ultrasonography for the prediction of malignancy in follicular thyroid neoplasms: systematic review and...
Use of color Doppler ultrasonography for the prediction of malignancy in follicular thyroid neoplasms: systematic review and ... in predicting malignancy in thyroid follicular neoplasms (FNs). METHODS:. We searched Medical Subject Headings together with ... We included studies that assessed the diagnostic accuracy of CDU in identifying malignancy in thyroid FNs. The assessments of ... Predominant internal flow seen on CDU is associated with malignancy of thyroid FNs. Absence of internal flow or predominantly ...
Unilateral thyroid neoplasm in a cat | Advanced Veterinary Medical Imaging
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) - MyPathologyReport.ca
... is a non-invasive type of thyroid tumour. ... Non-invasive follicular thyroid neoplasm with papillary-like ... Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a non-invasive type of thyroid tumour ... Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP).. Exclusion criteria. Your pathologist ... Is non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) a type of cancer?. NIFTP is a non- ...
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors
... kinase are specific and key oncogenic events in the onset of thyroid gland cancers such as the Medullary Thyroid Carcinoma (MTC ... Thyroid Gland / metabolism * Thyroid Gland / pathology * Thyroid Neoplasms / drug therapy* * Thyroid Neoplasms / metabolism ... kinase are specific and key oncogenic events in the onset of thyroid gland cancers such as the Medullary Thyroid Carcinoma (MTC ... Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors ...
Jong-In Park, PhD | Professor | Medical College of Wisconsin
Thyroid Neoplasms. Research Interests. Oncogenic transformation requires reprogramming in signaling and metabolism, which ... Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.. (Starenki D, Sosonkina N, Hong SK, ... in which medullary thyroid cancer is a key pathological presentation. As a member of the American Cancer Society MEN2 ... including thyroid cancer. For example, inherited RET mutations are an important prognostic marker for the multiple endocrine ...
Follicular neoplasms: The role for observation, fine needle aspiration biopsy, thyroid suppression, and surgery<...
Thyroid gland, Thyroid neoplasms, Thyroid nodule, Thyroidectomy, Thyrotropin, Triiodothyronine", ... Follicular neoplasms: The role for observation, fine needle aspiration biopsy, thyroid suppression, and surgery. Seminars in ... Follicular neoplasms : The role for observation, fine needle aspiration biopsy, thyroid suppression, and surgery. In: Seminars ... Follicular neoplasms : The role for observation, fine needle aspiration biopsy, thyroid suppression, and surgery. / Louis, ...
Classic Total Thyroidectomy With or Without Drains - Full Text View - ClinicalTrials.gov
Thyroid Neoplasms [C19.874.788]. Additional relevant MeSH terms:. Layout table for MeSH terms. ... Several techniques are employed in order to resect the suffering thyroid gland. Classic TT is considered today, the golden ... Patient had a previous thyroid operation. *Patient is participating in another clinical trial which may affect this studys ... surgery of the thyroid gland is considered safe with practically null mortality. Morbidity, although infrequent, is still a ...
Advanced Search Results - Public Health Image Library(PHIL)
Preoperative prediction of non-invasive follicular thyroid neoplasm with papillary-like nuclear features: a Canadian single...
... non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in April 2016. The purpose of this study ... An international group of experts recommended reclassifying non-invasive follicular variant of papillary thyroid cancers (FVPTC ... From: Preoperative prediction of non-invasive follicular thyroid neoplasm with papillary-like nuclear features: a Canadian ...
Jason Clain, M.D. | Harvard Catalyst Profiles | Harvard Catalyst
Solitary Thyroid Nodule Guidelines: Guidelines Summary
Diagnosis and management of pediatric endocrine neoplasms. Curr Opin Pediatr. 2009 Jun. 21(3):379-85. [QxMD MEDLINE Link]. ... Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2015 Jul. 25 (7):716-59. [ ... Thyroid nodules, thyroid function and dietary iodine in the Marshall islands. Int J Epidemiol. 1999 Aug. 28(4):742-9. [QxMD ... Canadian Pediatric Thyroid Nodule (CaPTN) Study Group. The Canadian Pediatric Thyroid Nodule Study: an evaluation of current ...
NIOSHTIC-2 Search Results - Full View
Exposure before age 8 to low doses of radioactive iodine was associated with increased risk of thyroid neoplasms and ... Epidemiology; Nuclear-energy; Nuclear-radiation; Nuclear-wastes; Radioactive-wastes; Thyroid-gland; Thyroid-gland-disorders; ... Thyroid disease associated with exposure to the Nevada test site radiation - a reevaluation based on corrected dosimetry and ... to radioactive iodine in fallout from nuclear weapons testing at the Nevada Test Site and the development of thyroid neoplasms ...
Pathology Residency Program | NorthShore
Portal Regional da BVS
Thyroid Gland, Thyroidectomy, Surgical Procedures, Operative, General Surgery, Therapeutics, Carcinoma, Thyroid Neoplasms, ... Medical Oncology, Neoplasms, Public Health, Internal Medicine, Diagnostic Techniques and Procedures, Clinical Medicine, Nursing ... Gastrointestinal Neoplasms, Lung Neoplasms, Lung, Health Promotion ... Breast Neoplasms, Breast, Drug Therapy, Diagnostic Services, 50233, Pathological Conditions, Signs and Symptoms, Breast ...
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Resection of an Intrathoracic Thyroid Gland | CTSNet
Chapter 4, Surgery for Neoplasms of the Thyroid gland. In Bland KI, Karakousis CP, Copeland EM, et al. Atlas of Surgical ... Leuchter I, Becker M, Mickel R, Dulguerov P. Horners syndrome and thyroid neoplasms. ORL J Otorhinolaryngol Relat Spec 2002;64 ... Ectopic intrathoracic thyroid is a rare presentation of thyroid disease and of all mediastinal tumors [3]. It is defined as the ... Nuclear Tc99 thyroid scan revealed a cold nodule in the right inferior thyroid gland extending below the sternum (Figure 4). ...
Multiple Cause Mortality 2002: List of 358 Selected Causes of Death
124 Malignant neoplasms of thyroid and other endocrine glands (C73-C75). 125 Other malignant neoplasms of other and unspecified ... 120 Malignant neoplasm of eye and adnexa (C69). 121 1 Malignant neoplasms of meninges, brain and other parts of central nervous ... 096 Malignant neoplasms of bone and articular cartilage (C40-C41). 097 1 Melanoma and other malignant neoplasms of skin (C43- ... 090 1 Malignant neoplasms of respiratory and intrathoracic organs (C30-C39). 091 Of nasal cavity, middle ear and accessory ...
Yan Shen's Research
| CureHunter
Thyrotropin - 505(b)(2) development and clinical trial profile - locations, diseases, companies
Thyroid Neoplasms. 4. [disabled in preview]. 0. This preview shows a limited data set. Subscribe for full access, or try a ... certain thyroid gland abnormalities. Normal thyroid gland function depends on proper chemical signaling between the thyroid ... Healthy volunteers between 18 and 65 years of age and all patients requiring TRH evaluation of hypothalamic-pituitary-thyroid ... Investigate whether a deficiency in endogenous cortisol and/or thyroid hormones after birth influences the severity of lung ...
GlandTumorsDifferentiated thyroid cancerCANCERAmerican Thyroid AssociationNodulesParathyroidCancersFine-needle aspCarcinomasMetastasisThyroiditisProstatic neoplasmsDiagnosisMalignant thyroidThyroidectomyBiopsyPituitaryRadioactive IodineMalignancyAnaplastic thyroid carcinomaSurgeryAdenomaPoorly differentiatedMalignanciesPatients With ThyroidSolitary thyroiClinicalTumourLymphomasHormoneLesions of the thyroidCarcinoma of the thyroidResectionThyroglobulinPulmonaryHistologicalNodule ManagementMetastatic thyroidDiseaseTissuesTissueAdenocarcinomaEndocrineLymphomaRadiotherapyVariant of follicular
Gland30
- Your thyroid is a small, butterfly-shaped gland in the front of your neck. (medlineplus.gov)
- Strazisar B, Petric R, Sesek M, Zgajnar J, Hocevar M, Besic N. Predictive factors of carcinoma in 279 patients with Hürthle cell neoplasm of the thyroid gland. (medscape.com)
- The diagnosis cannot be made after a small tissue sample is removed from the thyroid gland in a procedure called fine-needle aspiration. (mypathologyreport.ca)
- When examined under the microscope, the tumour cells in NIFTP are often separated from the surrounding normal thyroid gland by a thin tissue barrier called a tumour capsule . (mypathologyreport.ca)
- If no capsule is seen, the tumour cells should still be separated from the normal thyroid gland by a small space. (mypathologyreport.ca)
- Like the normal thyroid gland, NIFTP is made up of follicular cells that connect together to form follicles. (mypathologyreport.ca)
- Your pathologist also needs to examine the tumour to ensure it does not have other features that are seen in cancers of the thyroid gland but not in NIFTP. (mypathologyreport.ca)
- It is now known that "gain of function" mutations of RET (REarranged during Transfection) kinase are specific and key oncogenic events in the onset of thyroid gland cancers such as the Medullary Thyroid Carcinoma (MTC). (nih.gov)
- The diagnosis and management of follicular carcinoma of the thyroid gland remains a controversial topic. (utmb.edu)
- Nowadays, surgery of the thyroid gland is considered safe with practically null mortality. (clinicaltrials.gov)
- Several techniques are employed in order to resect the suffering thyroid gland. (clinicaltrials.gov)
- Nuclear Tc99 thyroid scan revealed a cold nodule in the right inferior thyroid gland extending below the sternum ( Figure 4 ). (ctsnet.org)
- At operation, through a cervical collar incision 2 cm above the supra-sternal notch, and with the neck extended, the right thyroid gland was explored. (ctsnet.org)
- The right thyroid gland extended into the middle mediastinum posterior to the innominate vein and lateral to the trachea. (ctsnet.org)
- The mass was subsequently removed, preserving the superior portion of the right thyroid gland, and measured 8 x 6 x 5 cm ( Figure 6 ). (ctsnet.org)
- Figure 6: Operative specimen - intra thoracic thyroid gland. (ctsnet.org)
- This study will determine the safety and activity of a new formulation of thyrotropin-releasing hormone (TRH), a drug used for diagnosing and evaluating patients with certain thyroid gland abnormalities. (drugpatentwatch.com)
- Normal thyroid gland function depends on proper chemical signaling between the thyroid gland, the hypothalamus (the part of the brain where TRH is made), and the pituitary (another part of the brain). (drugpatentwatch.com)
- Healthy volunteers between 18 and 65 years of age and all patients requiring TRH evaluation of hypothalamic-pituitary-thyroid gland interaction may be eligible for this study. (drugpatentwatch.com)
- It also ensures the proper functioning of the thyroid gland. (mdpi.com)
- However, Hodgkin s lymphoma affecting thyroid gland is very rare. (endocrine-abstracts.org)
- Thyroid nodules are growths or swellings on the thyroid gland. (southcarolinablues.com)
- Primary thyroid lymphoma can be defined as a lymphoma that arises from the thyroid gland. (medscape.com)
- [ 1 ] This definition excludes those that invade the thyroid gland as a consequence of either metastasis or direct extension. (medscape.com)
- The most common subtype of NHLs that arise primarily from the thyroid gland is diffuse large-cell lymphoma (DLBCL). (medscape.com)
- Lymphoma of the thyroid gland. (medscape.com)
- The book explains the metabolism of purines and pyrimidines in cancer, hypercalcemia in neoplastic disease without evidence of bone metastases, and neoplasms of other organs, such as the pituitary gland, thyroid, testis, and adrenal cortex. (elsevier.com)
- Tumors or cancer of the THYROID GLAND. (bvsalud.org)
- The thyroid gland has the function of secreting hormones that play an important role in metabolism. (bvsalud.org)
- Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
Tumors17
- Jung CK, Bychkov A, Kakudo K. Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach. (medscape.com)
- Pisanu A, Sias L, Uccheddu A. Factors predicting malignancy of Hürthle cell tumors of the thyroid: influence on surgical treatment. (medscape.com)
- Although the 2012 American Thyroid Association guidelines do not advocate molecular testing of anaplastic thyroid carcinoma tumors, selective BRAF inhibitors are being tested in patients with BRAF -mutated anaplastic thyroid carcinoma and may hold promise. (medscape.com)
- Ectopic intrathoracic thyroid is a rare presentation of thyroid disease and of all mediastinal tumors [3]. (ctsnet.org)
- Patients include those with pituitary reserve, inconsistent thyroid function test, inappropriate TSH secretion, or pre- and post-operative evaluation of pituitary tumors. (drugpatentwatch.com)
- OBJECTIVE: This study aims to evaluate the diagnostic value of ultrasound in thyroid Hürthle cell tumors. (iospress.com)
- METHODS: A retrospective analysis was carried out on 27 patients with thyroid Hürthle cell tumors, in terms of the size, shape, boundary, echo, aspect ratio, cystic degeneration, calcification, peripheral halo sign and blood supply of the tumor, through surgical pathological validation. (iospress.com)
- RESULTS: The maximum diameter of the thyroid Hürthle cell tumors is between 0.6 cm and 4.6 cm. (iospress.com)
- Biochemistry of Human Cancer focuses on advances in the application of biochemistry to the study of human cancers, such as neoplastic immunoglobulinopathies, cancer of the bladder, tumors of the neural crest, leukemias and lymphomas, and neoplasms of the bone. (elsevier.com)
- The remaining chapters look at the role of enzymes and immunoglobulins in cancer, the tryptophan metabolism in cancer of the bladder and the carcinoid syndrome, the link between amino acid metabolism and tumors of the neural crest, and the neoplasms of the digestive tract and the accessory organs (pancreas and liver). (elsevier.com)
- Thyroid cancer cell line mutations recapitulate those found in primary tumors (e.g. (elsevier.com)
- Thyroid carcinomas are uncommon tumors in pediatric patients. (lww.com)
- Tumors derived from the thyroid follicle are well-differentiated thyroid carcinomas (WDTC) and include papillary thyroid carcinomas (PTC) and follicular thyroid carcinomas (FTC). (lww.com)
- These tumors, although rare (about 2 and 5% of thyroid cancer cases, respectively) ( 3 ), represent the most aggressive thyroid tumors but their median survival time is rather different being of 6-12 months and 3-5 years for ATC and PDTC, respectively ( 4 , 5 ). (spandidos-publications.com)
- However, at least two or three histological classifications to better distinguish these two types of advanced thyroid tumors have been proposed and the one chosen by the pathologist for the diagnosis should be indicated in the pathological report ( 8 , 9 ). (spandidos-publications.com)
- for this reason, a more tailored disease management will be possible.Thyroid cancer is the most prevalent neoplasm among endocrine tumors, presenting an increasing incidence trend over the last few years. (unimi.it)
- The role of electron microscopy in characterization of uncommon epithelial pulmonary neoplasms, metastatic neoplasms to and from lung and other tumors, including mesenchymal neoplasms. (uab.edu)
Differentiated thyroid cancer4
- The American Thyroid Association (ATA) issued management guidelines for children with thyroid nodules and differentiated thyroid cancer. (medscape.com)
- In this article we review the treatment of both well differentiated thyroid cancer (WDTC), as well as medullary thyroid cancer (MTC). (lww.com)
- Anaplastic (ATC) and poorly differentiated thyroid cancer (PDTC) are very aggressive cancers whose histological diagnosis is not always straightforward. (spandidos-publications.com)
- Anaplastic (ATC) and poorly differentiated thyroid cancer (PDTC) take origin from the follicular cells but during the process of tumoral transformation, they lose progressively the typical features of these cells, being the ATC completely undifferentiated while PDTC showing an intermediate spectrum of differentiation ( 1 , 2 ). (spandidos-publications.com)
CANCER58
- Treatment of thyroid cancer in childhood : proceedings of a workshop held September 10-11, 1992, at the National Institutes of Health, in Bethesda, Maryland / edited by Jacob Robbins. (who.int)
- What is thyroid cancer? (medlineplus.gov)
- Thyroid cancer is a cancer that starts in the tissues of the thyroid. (medlineplus.gov)
- What are the different types of thyroid cancer? (medlineplus.gov)
- Who is more likely to develop thyroid cancer? (medlineplus.gov)
- Certain people are more likely to develop thyroid cancer. (medlineplus.gov)
- What are the symptoms of thyroid cancer? (medlineplus.gov)
- Thyroid cancer may not cause symptoms at first. (medlineplus.gov)
- How is thyroid cancer diagnosed? (medlineplus.gov)
- What are the treatments for thyroid cancer? (medlineplus.gov)
- Treatment for thyroid cancer depends on the type of cancer you have and whether the cancer has spread. (medlineplus.gov)
- Can Thyroid Cancer Be Found Early? (medlineplus.gov)
- Can Thyroid Cancer Be Prevented? (medlineplus.gov)
- It is called pre-cancerous because if not removed, it can over time turn into a type of cancer called papillary thyroid carcinoma . (mypathologyreport.ca)
- NIFTP is a non-invasive type of thyroid cancer. (mypathologyreport.ca)
- However, unlike other types of thyroid cancer, it has a very low malignant potential which means it is very unlikely to spread to lymph nodes or other parts of the body. (mypathologyreport.ca)
- At that time, it was also considered a type of thyroid cancer. (mypathologyreport.ca)
- The follicular cells show changes that pathologists describe as "papillary-like nuclear features" because they look similar to the cells in a type of cancer called papillary thyroid carcinoma . (mypathologyreport.ca)
- Papilla are very commonly seen in a type of cancer called papillary thyroid carcinoma and are not seen in NIFTP. (mypathologyreport.ca)
- See Thyroid Cancer Staging . (medscape.com)
- Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies. (medscape.com)
- Fine needle aspiration, although very sensitive with other types of thyroid cancer, has limited accuracy with follicular lesions. (utmb.edu)
- Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study. (medscape.com)
- Thyroid nodules in pediatric patients: sonographic characteristics and likelihood of cancer. (medscape.com)
- Busko M. ATA Issues First Advice for Thyroid Nodules, Cancer in Children. (medscape.com)
- The recommendations apply to thyroid nodules ≥1 cm in maximal diameter, evaluated by ultrasonography, in adult patients without a history of thyroid cancer 1 . (radiopaedia.org)
- However, these nodules may also be caused by thyroid cancer, which occurs in 4-6.5% of nodules. (southcarolinablues.com)
- A cohort study of 2215 patients with primary thyroid lymphoma from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute reported 5- and 10-year overall survival rates of 71.61% and 55.95%, respectively. (medscape.com)
- Mice study showed that CSF1/CSF1R mediated TAMs recruitment in papillary thyroid cancer (PTC) and targeting CSF1/CSF1R impaired BRAF-induced thyroid cancer progression [ 21 ]. (biomedcentral.com)
- Purpose: Thyroid cancer cell lines are valuable models but have been neglected in pancancer genomic studies. (elsevier.com)
- We aim to provide a validated dataset for thyroid cancer researchers. (elsevier.com)
- 1 The incidence of thyroid cancer increases rapidly between 15 and 29 years of age, and reaches a plateau by the fifth to sixth decades. (lww.com)
- In the United States from 1975 to 2000, thyroid cancer accounted for about 10% of all malignancies diagnosed in individuals 15 to 29 years of age and was the fourth most common cancer in this age group. (lww.com)
- The study excluded patients who had undergone partial thyroidectomy, patients who had been operated on with minimally invasive techniques, patients operated on for an overactive nodular goiter, recurrent goiter, cancer or suspected thyroid cancer, patients with clinical signs of vocal fold palsy before surgery, and patients with diseases of the central or peripheral nervous system that may cause damage to the motor system or neuron of the motor system. (researchsquare.com)
- This practical guide to the management of thyroid nodules and cancer offers the practitioner a common-sense approach to the management of an increasingly common clinical problem. (novapublishers.com)
- Thyroid cancer is the most rapidly increasing cancer diagnosis in the United States and is now the fifth most common cancer among women. (novapublishers.com)
- Indeed, an estimated 65,000 adults (15,000 men and 50,000 women) in the United States will be diagnosed this year with thyroid cancer. (novapublishers.com)
- Practitioners seeking to help their patients and make sense of conflicting thyroid cancer guidelines will discover illustrative cases that represent common situations in clinical practice. (novapublishers.com)
- Follicular Variant Papillary Cancer-Some Variants are now Reclassified as "Vanishing Thyroid Cancer" Syndrome (Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features=NIFTP)! (novapublishers.com)
- Multikinase inhibitors have shown improved clinical outcome and implemented tumor response in advanced thyroid cancer. (unimi.it)
- Targeted agents for advanced thyroid cancer: 'knowledge is power'- the role of multikinase inhibitors / A. Mangano, H.Y. Kim, G.D. Lianos, D.H. Roukos, G. Dionigi. (unimi.it)
- Breast cancer is the most common neoplasm to metastasize to the oral cavity altogether. (washington.edu)
- Dr. Zhang's research accomplishments include the discovery of diagnostic markers to distinguish thyroid cancer from benign growths and to differentiate between the precursor lesion for esophageal cancer (squamous dysplasia) and other reactive changes in the esophagus. (mayo.edu)
- Dr. Zhang and colleagues also detected chromosomal alterations by florescence in situ hybridization (FISH) in urothelial carcinoma and rarer histologic variants of bladder cancer, and discovered the diagnostic utility of combination of HMGA2 and IMP3 qRT-PCR in thyroid neoplasms. (mayo.edu)
- Molecular markers for thyroid cancer. (mayo.edu)
- Dr. Zhang is developing molecular diagnostic markers for thyroid cancer and collaborating with endocrinologists at Mayo Clinic to develop prognostic markers. (mayo.edu)
- The tumor-formerly called EFVPTC (encapsulated follicular variant of papillary thyroid carcinoma) but now known as NIFTP (noninvasive follicular thyroid neoplasm with papillary-like nuclear features), with no C on the end to designate 'carcinoma'-is estimated to make up between 10% and 20% of all thyroid cancer diagnoses in Northern America and Europe, according to a press release . (newser.com)
- All those people were diagnosed with cancer, which is terrifying psychologically for a patient, and also leads to aggressive, risky-and now officially unnecessary-treatments, such as the removal of the thyroid and radioactive iodine treatments. (newser.com)
- If it's not a cancer, let's not call it a cancer,' the president-elect of the American Thyroid Association tells the Times . (newser.com)
- Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing. (cdc.gov)
- Thyroid cancers represent approximately 1% of new cancer diagnoses in the United States each year. (medscape.com)
- For summarized information on staging and treatment, see Thyroid Cancer Staging and Thyroid Cancer Treatment Protocols . (medscape.com)
- Other studies which have included construction laborers as part of their cohort have observed findings similar to those of ours, with the exception of the excess risk of thyroid cancer. (cdc.gov)
- The data presented in this edition of Cancer Incidence in Five The CI5 data include all invasive malignant neoplasms and Continents (CI5) are mainly organised according to anatomical some non-invasive malignant neoplasms For most morphology site However, for some sites, the histological type of cancer codes, a fifth digit /1 or /2 automatically excludes the data entry. (who.int)
- Other specified malignant neoplasm (Other specified cancer tumour Other codes are obsolete, ie the entities have been in the previous edition). (who.int)
- A neoplasm and malignant tumour are other common names for cancer. (who.int)
- Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. (who.int)
- The National Comprehensive Cancer Network (NCCN) and the European Society for Medical Oncology recommend consideration of molecular diagnostic testing in patients with indeterminate cytology, including follicular neoplasms to help predict malignancy, assist in management decisions, and aid in identification of clinical trials. (medscape.com)
American Thyroid Association1
- According to the American Thyroid Association guidelines , this patient should now be managed in the same way as a cytologically confirmed thyroid carcinoma. (medscape.com)
Nodules20
- For children at high risk for thyroid neoplasia, an annual physical examination is recommended and if the examination finds palpable nodules, thyroid asymmetry, and/or abnormal cervical lymphadenopathy, additional imaging is warranted. (medscape.com)
- Evaluation of cytologically benign solitary thyroid nodules by ultrasonography: A retrospective analysis of 1877 cases. (medscape.com)
- Management of thyroid nodules in children: a 20-year experience. (medscape.com)
- Thyroid nodules in children: current profile of a changing disease. (medscape.com)
- Solitary thyroid nodules in 71 children and adolescents. (medscape.com)
- Hung W. Solitary thyroid nodules in 93 children and adolescents. (medscape.com)
- Al-Shaikh A, Ngan B, Daneman A, Daneman D. Fine-needle aspiration biopsy in the management of thyroid nodules in children and adolescents. (medscape.com)
- Pediatric thyroid nodules: management in the era of fine needle aspiration. (medscape.com)
- Deng F, Knipe H, SRU guidelines for assessment of thyroid nodules. (radiopaedia.org)
- The Society of Radiologists in Ultrasound (SRU) guidelines for the assessment of thyroid nodules were defined in a consensus conference statement published in 2005 focused on which thyroid nodules detected on ultrasonography should undergo fine needle aspiration . (radiopaedia.org)
- Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. (radiopaedia.org)
- Core needle biopsy of thyroid nodules - evaluation of diagnostic utility and pain experience. (nel.edu)
- A crucial problem in the non-operative diagnosis of thyroid nodules is the significant amount of non-diagnostic biopsies. (nel.edu)
- Stangierski A, Wolinski K, Martin K, Leitgeber O, Ruchala M. Core needle biopsy of thyroid nodules - evaluation of diagnostic utility and pain experience. (nel.edu)
- Many more will be treated for thyroid nodules. (novapublishers.com)
- Alterations in this function may bring complications to individuals, among them thyroid nodules. (bvsalud.org)
- The prevalence of thyroid nodules is higher in white people, older adults, women, smokers, with accumulated body fat and larger waist circumference. (bvsalud.org)
- The aim of this study was to compare dietary intake of patients with benign (BN) and malignant (MN) thyroid nodules. (bvsalud.org)
- History taking, physical examination, laboratory evaluation, and fine-needle aspiration biopsy (FNAB) are the mainstays in the evaluation of thyroid nodules. (medscape.com)
- FNAB is the most important diagnostic tool in evaluating thyroid nodules and should be the first intervention. (medscape.com)
Parathyroid6
- Obtain serum calcium levels to rule out medullary thyroid carcinoma or parathyroid neoplasms. (medscape.com)
- Dr Chambers has an active clinical research program with a focus on diseases of the breast, thyroid and parathyroid glands, and neuroendocrine tumours. (edu.au)
- Thyroid and Parathyroid Surgery: New and Emerging Concepts. (elsevier.com)
- A prospective study to compare the efficacy of ICG dye Angiography and Parathyroid Hormone measurement in early prediction of risk of decrease in blood calcium levels after thyroid surgery. (who.int)
- 6. Previous thyroid and parathyroid surgery. (who.int)
- Hypoparathyroidism (HypoPT) is a rare (orphan) endocrine disease with low calcium and inappropriately low (insufficient) circulating parathyroid hormone levels, most often in adults secondary to thyroid surgery. (bvsalud.org)
Cancers3
- Experimental Design: We performed next-generation sequencing (NGS) and analyzed the transcriptome of 60 authenticated thyroid cell lines and compared our findings with the known genomic defects in human thyroid cancers. (elsevier.com)
- Thyroid cancers represent the largest group of pediatric carcinomas. (lww.com)
- Lung and prostate cancers are the most common neoplasms to metastasize to the oral cavity in men. (washington.edu)
Fine-needle asp1
- Ultrasonography is an essential imaging technique for evaluation of thyroid masses and is used to guide fine-needle aspiration cytologic and core needle biopsy procedures. (medscape.com)
Carcinomas9
- Bronner MP, Clevenger CV, Edmonds PR, Lowell DM, McFarland MM, LiVolsi VA. Flow cytometric analysis of DNA content in Hürthle cell adenomas and carcinomas of the thyroid. (medscape.com)
- Thyroid carcinomas and lung adenocarcinoma share cytomorphological features yet have different prognoses. (elsevier.com)
- Thyroid carcinomas can be classified according to the cell of origin. (lww.com)
- In general, PTC represents about 80% and FTC accounts for approximately 20% of the differentiated thyroid carcinomas. (lww.com)
- Medullary thyroid carcinomas (MTC) are derived from calcitonin-producing cells and account for 5% to 10% of thyroid carcinomas. (lww.com)
- Theoretically, any malignant neoplasm can metastasize to the oral cavity, but in actuality few do and of the ones that do, the majority is carcinomas. (washington.edu)
- In both efforts, he works with cytology and paraffin-embedded specimens of thyroid carcinomas. (mayo.edu)
- Thyroid malignancies are divided into papillary carcinomas (80%), follicular carcinomas (10%), medullary thyroid carcinomas (5-10%), anaplastic carcinomas (1-2%), primary thyroid lymphomas (rare), and primary thyroid sarcomas (rare). (medscape.com)
- Hürthle cell carcinomas account for 2-3% of all thyroid malignancies. (medscape.com)
Metastasis1
- A rare case of pulmonary metastasis has been reported in a 65-year-old woman diagnosed with a primary thyroid MALToma who underwent total thyroidectomy, followed by chemotherapy. (medscape.com)
Thyroiditis3
- Exposure before age 8 to low doses of radioactive iodine was associated with increased risk of thyroid neoplasms and thyroiditis in this cohort. (cdc.gov)
- Thyroid lymphomas are very frequently associated with Hashimoto thyroiditis . (medscape.com)
- patients with Hashimoto thyroiditis have a 60 times higher risk of developing primary thyroid lymphoma, compared with the general population. (medscape.com)
Prostatic neoplasms1
- It then discusses the important biochemical aspects of pulmonary and prostatic neoplasms, including the serum acid and alkaline phosphatase activities of prostatic carcinoma. (elsevier.com)
Diagnosis7
- General comment: I do not believe that the material recovered from a cystic fluid (if indeed the nodule is entirely fluid) can allow the diagnosis of follicular neoplasm. (thyroidmanager.org)
- How do pathologists make the diagnosis of non-invasive follicular thyroid neoplasm with papillary-like nuclear features? (mypathologyreport.ca)
- Diagnosis of anaplastic thyroid carcinoma (ATC) requires cytologic examination of tumor tissue. (medscape.com)
- The pathological diagnosis confirmed a benign thyroid adenoma. (ctsnet.org)
- OBJECTIVE: To assess the possible contribution by a multiparametric quantitative approach to the cytologic diagnosis of oxyphilic cell (OC) thyroid lesions. (elsevier.com)
- The differential diagnosis of follicular thyroid carcinoma (FTC) and follicular adenoma (FA) before surgery is a clinical challenge. (biomedcentral.com)
- This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
Malignant thyroid2
- Nearly 2400 individuals, 15 to 29 years of age were diagnosed with a malignant thyroid neoplasm in the United States during the year 2000. (lww.com)
- Mucoepidermoid carcinoma (MEC) is a rare malignant thyroid neoplasm. (scilit.net)
Thyroidectomy1
- Thyroid hormone therapy is used to replace endogenous production after thyroidectomy and radioactive iodine therapy. (medscape.com)
Biopsy1
- We included 4 studies, which collectively evaluated 457 thyroid FNs, 67 of which had been classified as malignant based on the evaluation of surgical biopsy samples. (bvsalud.org)
Pituitary1
- The anterior pituitary produces six major hormones: (1) prolactin (PRL), (2) growth hormone (GH), (3) adrenocorticotropin hormone (ACTH), (4) luteinizing hormone (LH), (5) follicle-stimulating hormone (FSH), and (6) thyroid-stimulating hormone (TSH). (mhmedical.com)
Radioactive Iodine1
- In 1993 we reported an association between exposure to radioactive iodine in fallout from nuclear weapons testing at the Nevada Test Site and the development of thyroid neoplasms in a cohort of 2473 exposed as children, and followed for up to 38 years. (cdc.gov)
Malignancy10
- Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy. (medscape.com)
- Use of color Doppler ultrasonography for the prediction of malignancy in follicular thyroid neoplasms: systematic review and meta-analysis. (bvsalud.org)
- The purpose of this systematic review was to obtain summary estimates of the diagnostic accuracy of color Doppler ultrasonography (CDU) in predicting malignancy in thyroid follicular neoplasms (FNs). (bvsalud.org)
- We included studies that assessed the diagnostic accuracy of CDU in identifying malignancy in thyroid FNs. (bvsalud.org)
- Moderate, rich, predominant, or exclusive internal flow on CDU of thyroid FNs was considered indicative of malignancy . (bvsalud.org)
- Predominant internal flow seen on CDU is associated with malignancy of thyroid FNs. (bvsalud.org)
- Absence of internal flow or predominantly peripheral flow indicates a low probability of thyroid FN malignancy . (bvsalud.org)
- For an intrathoracic thyroid, surgical removal is indicated when the mass is large, when there is local compression of adjacent structures, and when there is a possibility of malignancy. (ctsnet.org)
- The "Indeterminate" Thyroid FNA-What Additional Genomic Testing can Help Differentiate Malignancy Risk? (novapublishers.com)
- Hürthle cell carcinoma is a rare thyroid malignancy that is often considered a variant of follicular carcinoma. (medscape.com)
Anaplastic thyroid carcinoma4
- All patients with anaplastic thyroid carcinoma are classified as having stage IV disease, because of the high mortality of the disease. (medscape.com)
- Cabanillas ME, Zafereo M, Gunn GB, Ferrarotto R. Anaplastic Thyroid Carcinoma: Treatment in the Age of Molecular Targeted Therapy. (medscape.com)
- Identification of novel therapeutic targets in anaplastic thyroid carcinoma using functional genomic mRNA-profiling: Paving the way for new avenues? (medscape.com)
- Cases of MEC with papillary, insular, and anaplastic thyroid carcinoma have been reported. (scilit.net)
Surgery2
- Thyroid surgery has evolved over the years from one of the most dangerous procedures to operations that are not only safe, but also well-tolerated and complication rates are low. (researchsquare.com)
- In an indirect laryngoscopic examination performed by a laryngologist before the surgery, no disturbances in the mobility of the vocal folds were found, and no other voice disorders unrelated to thyroid diseases in the form of hoarseness, aphonia, dyspnea or laryngeal wheezing were found. (researchsquare.com)
Adenoma1
- However, its accuracy has been largely compromised for follicular lesions, namely follicular thyroid carcinoma (FTC) and follicular adenoma (FA). (biomedcentral.com)
Poorly differentiated1
- Rule out lymphoma in the presence of a poorly differentiated large cell thyroid tumor. (medscape.com)
Malignancies4
- 5% of thyroid malignancies. (endocrine-abstracts.org)
- It represents less than 5% of thyroid malignancies. (medscape.com)
- primary thyroid lymphoma may constitute 1-8% of all thyroid malignancies and 1-7% of all extranodal lymphomas. (medscape.com)
- The clinical presentation is similar to that of other thyroid malignancies. (medscape.com)
Patients With Thyroid3
- As with other non-Hodgkin lymphomas, the median age of presentation in patients with thyroid lymphoma is approximately 60 years. (medscape.com)
- The prognosis for patients with thyroid large-cell lymphoma usually is favorable because they typically present with localized disease, which is amenable to treatment with chemotherapy and radiation (see Treatment ). (medscape.com)
- Patients with thyroid eye disease often have associated globe proptosis and lid lag along with eyelid retraction. (eyewiki.org)
Solitary thyroi3
- Bentley AA, Gillespie C, Malis D. Evaluation and management of a solitary thyroid nodule in a child. (medscape.com)
- Thyroid carcinoma most commonly manifests as a painless, palpable, solitary thyroid nodule. (medscape.com)
- The key to the workup of the solitary thyroid nodule is to differentiate malignant from benign disease and, thus, to determine which patients require intervention and which patients may be monitored serially. (medscape.com)
Clinical5
- An aged cat with a thyroid neoplasm showed clinical signs and had laboratory data and post mortem findings similar to those observed in human and canine patients afflicted with hyperthyroidism. (avmi.net)
- In light of additional clinical information and TGB immunostain, the diagnoses of these two cases changed to metastatic thyroid carcinoma. (elsevier.com)
- Commercially available panels of molecular markers utilizing FNA specimens from the thyroid are currently considered to be laboratory-developed tests (LDTs), which are regulated by the Centers for Medicare & Medicaid Services (CMS) as high-complexity tests under the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88). (southcarolinablues.com)
- Clinical Significance of Thyroid-Stimulating Hormone Receptor Gene Mutations and/or Sodium-Iodine Symporter Gene Overexpression in Indeterminate Thyroid Fine Needle Biopsies. (bu.edu)
- To Study the Prevalence of Different Forms of Thyroid Dysfunctions, Their Risk Factors and Clinical Implications in Cases of Type 2 Diabetes Mellitus, Presenting at Tertiary Care Hospital of Kumaon Region of Uttarakhand. (aimdrjournal.com)
Tumour4
- Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a non-invasive type of thyroid tumour. (mypathologyreport.ca)
- The tumour was described as non-invasive because the entire tumour was surrounded by a capsule and the tumour cells were not seen spreading into or invading the normal thyroid tissue. (mypathologyreport.ca)
- This examination needs to be performed in order to make sure that the tumour cells do not cross the tumour capsule or spread into the normal surrounding thyroid tissue. (mypathologyreport.ca)
- The terms 'neoplasm' and 'tumour' are used interchangeably. (who.int)
Lymphomas1
- Primary thyroid lymphomas are practically always non-Hodgkin lymphomas (NHLs). (medscape.com)
Hormone3
- Thyroid hormone therapy. (medlineplus.gov)
- The values of total thyroxin 3 (TT3), total thyroxin 4 (TT4), free thyroxin 3 (FT3), free thyroxin 4 (FT4), and thyroid stimulating hormone (TSH) were all normal. (ctsnet.org)
- Lastly, suppression of thyroid stimulating hormone (TSH) may be one of the most beneficial treatments for WDTC. (lww.com)
Lesions of the thyroid1
- Hürthle cell lesions of the thyroid: Progress made and challenges remaining. (medscape.com)
Carcinoma of the thyroid1
- Grossly, anaplastic carcinoma of the thyroid (ATC) is a large, fleshy, off-white tumor. (medscape.com)
Resection1
- Classic TT is considered today, the golden standard of total thyroid resection. (clinicaltrials.gov)
Thyroglobulin1
- Thyroid Transcription Factor-1 (TTF-1) is an immunohistochemical (IHC) marker used to confirm pulmonary and thyroid carcinoma, while Thyroglobulin (TGB) is expressed by thyroid carcinoma. (elsevier.com)
Pulmonary2
- Herrera GA, Alexander CB, Jones M. Ultrastructural characterization of pulmonary neoplasms I. The role of electron microscopy in characterization of the most common epithelial neoplasms. (uab.edu)
- Herrera GA, Alexander CB, Jones M. Ultrastructural characterization of pulmonary neoplasms II. (uab.edu)
Histological2
Nodule Management1
- Utilities of RAS Mutations in Preoperative Fine Needle Biopsies for Decision Making for Thyroid Nodule Management: Results from a Single-Center Prospective Cohort. (bu.edu)
Metastatic thyroid1
- After 5 years of follow-up, she was diagnosed with metastatic thyroid MALT lymphoma. (medscape.com)
Disease11
- Cannon J. The significance of hurthle cells in thyroid disease. (medscape.com)
- Chiesa F. Thyroid disease in northern Italian children born around the time of the Chernobyl nuclear accident. (medscape.com)
- Nodular thyroid disease in children and adolescents. (medscape.com)
- Thyroid disease associated with exposure to the Nevada test site radiation - a reevaluation based on corrected dosimetry and examination data. (cdc.gov)
- A panel of three medical experts, blinded to the exposure history of the subjects and using the most recent diagnostic criteria, reviewed the medical history of the 358 subjects with thyroid disease. (cdc.gov)
- Investigate whether a deficiency in endogenous cortisol and/or thyroid hormones after birth influences the severity of lung disease and the development of chronic lung disease. (drugpatentwatch.com)
- The purpose of this study is to evaluate the type and frequency of thyroid disease most often associated with acromegaly patients.Material and methods: We conducted a retrospective observational study analysing the data from the observation charts of 77 patients with acromegaly (58 fem. (endocrine-abstracts.org)
- The most common causes of upper eyelid retraction include thyroid eye disease, recession of superior rectus muscle, and contralateral ptosis. (eyewiki.org)
- The most common cause of unilateral or bilateral upper eyelid retraction is Graves' ophthalmopathy, or thyroid eye disease. (eyewiki.org)
- Upper eyelid retraction in thyroid eye disease often has temporal flare, when retraction is more pronounced at the lateral aspect of the eyelid. (eyewiki.org)
- If thyroid eye disease has been ruled out, Bartley proposed three categories of upper eyelid retraction: neurogenic, myogenic, and mechanistic causes. (eyewiki.org)
Tissues2
- Compound 5 was able to significantly reduce proliferation of both commercially available TT cell lines and surgical thyroid tissues obtained from patients with MTC and displayed a suitable drug-like profile, thus standing out as a promising candidate for further development towards the treatment of clinically unresponsive MTC. (nih.gov)
- A 12-year-old neutered male Husky dog had a neoplasm at the base of the heart which did not invade surrounding tissues. (avmi.net)
Tissue4
- It is defined as the presence of enlarged thyroid tissue below the plane of the thoracic inlet. (ctsnet.org)
- Malignant struma ovarii is a rare ovarian neoplasm composed predominantly of mature thyroid tissue. (nel.edu)
- Adjacent to the neoplasm was a rim of ectopic thyroid tissue that appeared histologically normal. (avmi.net)
- Malignant neoplasms of the kidney can originate from different types of tissue. (krebsdaten.de)
Adenocarcinoma5
- The cytopathology archive of The Johns Hopkins Hospital was searched for cases of lung adenocarcinoma versus thyroid carcinoma with TTF-1 and TGB IHC. (elsevier.com)
- Forty-four cases of lung adenocarcinoma (25) and thyroid carcinoma (19) were retrieved. (elsevier.com)
- One was metastatic lung adenocarcinoma to the thyroid and three were metastatic papillary thyroid carcinoma (PTC) to the lung. (elsevier.com)
- TTF-1 and TGB is a small immunostain panel that can differentiate lung adenocarcinoma from thyroid carcinoma and prevent misdiagnosis and its consequences. (elsevier.com)
- Sathiyamoorthy, S & Maleki, Z 2014, ' Cytomorphologic overlap of differentiated thyroid carcinoma and lung adenocarcinoma and diagnostic value of TTF-1 and TGB on cytologic material ', Diagnostic cytopathology , vol. 42, no. 1, pp. 5-10. (elsevier.com)
Endocrine1
- The ICD-10 code range for Malignant neoplasms of thyroid and other endocrine glands C73-C75 is medical classification list by the World Health Organization (WHO). (aapc.com)
Lymphoma6
- Thyroid lymphoma is the only curable condition that may be confused with ATC. (medscape.com)
- Primary thyroid Hodgkin lymphoma is extremely rare. (medscape.com)
- It has also been reported that a mutation or deletion in A20, which is a negative regulator of NF-кB signaling pathway, plays a role in the pathogenesis of certain subsets of thyroid B-cell lymphoma, especially MALTomas. (medscape.com)
- Primary thyroid lymphoma is rare. (medscape.com)
- Kesireddy M, Lasrado S. Thyroid Lymphoma. (medscape.com)
- The significance of MALT histology in thyroid lymphoma: a review of patients from the BNLI and Royal Marsden Hospital. (medscape.com)
Radiotherapy1
- Radiotherapy is a mode of treatment that is often used for malign neoplasms of the head and neck and has a significant cure rate, although it is associated with various oral complications 2 . (bvsalud.org)
Variant of follicular1
- Accumulation of p27(kip1) is associated with cyclin D3 overexpression in the oxyphilic (Hurthle cell) variant of follicular thyroid carcinoma. (medscape.com)