A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.
Tumors or cancer of the THYROID GLAND.
Pathological processes involving the THYROID GLAND.
Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.
A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.
A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Blood tests used to evaluate the functioning of the thyroid gland.
Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Surgical removal of the thyroid gland. (Dorland, 28th ed)
Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).
A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.
A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly proteins. EC 1.11.1.8.
Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis.
A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)
Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
MAMMARY GLANDS in the non-human MAMMALS.
Inflammatory diseases of the THYROID GLAND. Thyroiditis can be classified into acute (THYROIDITIS, SUPPURATIVE), subacute (granulomatous and lymphocytic), chronic fibrous (Riedel's), chronic lymphocytic (HASHIMOTO DISEASE), transient (POSTPARTUM THYROIDITIS), and other AUTOIMMUNE THYROIDITIS subtypes.
Agents that are used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)
Glands of external secretion that release its secretions to the body's cavities, organs, or surface, through a duct.
An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed)
Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.
Inorganic binary compounds of iodine or the I- ion.
An enlarged THYROID GLAND containing multiple nodules (THYROID NODULE), usually resulting from recurrent thyroid HYPERPLASIA and involution over many years to produce the irregular enlargement. Multinodular goiters may be nontoxic or may induce THYROTOXICOSIS.
A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.
Defective development of the THYROID GLAND. This concept includes thyroid agenesis (aplasia), hypoplasia, or an ectopic gland. Clinical signs usually are those of CONGENITAL HYPOTHYROIDISM.
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
Compounds that contain the Cl(=O)(=O)(=O)O- structure. Included under this heading is perchloric acid and the salts and ester forms of perchlorate.
Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspected of terato- and carcinogenesis.
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
The largest of the three pairs of SALIVARY GLANDS. They lie on the sides of the FACE immediately below and in front of the EAR.
A degradation product of ethylenebis(dithiocarbamate) fungicides. It has been found to be carcinogenic and to cause THYROID hyperplasia.
Cell surface proteins that bind pituitary THYROTROPIN (also named thyroid stimulating hormone or TSH) and trigger intracellular changes of the target cells. TSH receptors are present in the nervous system and on target cells in the thyroid gland. Autoantibodies to TSH receptors are implicated in thyroid diseases such as GRAVES DISEASE and Hashimoto disease (THYROIDITIS, AUTOIMMUNE).
An inorganic compound that is used as a source of iodine in thyrotoxic crisis and in the preparation of thyrotoxic patients for thyroidectomy. (From Dorland, 27th ed)
A mass of histologically normal tissue present in an abnormal location.
A diverticulum from the fourth pharyngeal pouch of an embryo, regarded by some as a rudimentary fifth pharyngeal pouch and by others as a lateral thyroid primordium. The ultimobranchial bodies of lower vertebrates contain large amounts of calcitonin. In mammals the bodies fuse with the thyroid gland and are thought to develop into the parafollicular cells. (Stedman, 25th ed)
A benign epithelial tumor with a glandular organization.
Sweat-producing structures that are embedded in the DERMIS. Each gland consists of a single tube, a coiled body, and a superficial duct.
A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.
A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyroid cells and acts to decrease the formation and absorptive activity of osteoclasts. Its role in regulating plasma calcium is much greater in children and in certain diseases than in normal adults.
Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.
A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).
Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.
A salivary gland on each side of the mouth below the TONGUE.
A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
A dehydrated extract of thyroid glands from domesticated animals. After the removal of fat and connective tissue, the extract is dried or lyophilized to yield a yellowish to buff-colored amorphous powder containing 0.17-0.23% of iodine.
The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH requires the non-covalently bound heterodimers of an alpha and a beta subunit.
A compound forming white, odorless deliquescent crystals and used as iodine supplement, expectorant or in its radioactive (I-131) form as an diagnostic aid, particularly for thyroid function tests.
A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Using fine needles (finer than 22-gauge) to remove tissue or fluid specimens from the living body for examination in the pathology laboratory and for disease diagnosis.
A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.
A sebaceous gland that, in some animals, acts as an accessory to the lacrimal gland. The harderian gland excretes fluid that facilitates movement of the third eyelid.
A group of metabolites derived from THYROXINE and TRIIODOTHYRONINE via the peripheral enzymatic removal of iodines from the thyroxine nucleus. Thyronine is the thyroxine nucleus devoid of its four iodine atoms.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
A dangerous life-threatening hypermetabolic condition characterized by high FEVER and dysfunction of the cardiovascular, the nervous, and the gastrointestinal systems.
Tumors or cancer of the SALIVARY GLANDS.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints.
Large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askenazy cells.
The measurement of an organ in volume, mass, or heaviness.
A product from the iodination of tyrosine. In the biosynthesis of thyroid hormones (THYROXINE and TRIIODOTHYRONINE), tyrosine is first iodized to monoiodotyrosine.
An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)
A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus.
A cyst in the neck caused by persistence of portions of, or by lack of closure of, the primitive thyroglossal duct. (Dorland, 27th ed)
Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.
Infection of the ENDOCRINE GLANDS with species of MYCOBACTERIUM, most often MYCOBACTERIUM TUBERCULOSIS.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
A class of thiocarbamate derivatives whose salts possess fungicidal activity.
April 25th -26th, 1986 nuclear power accident that occurred at Chernobyl in the former USSR (Ukraine) located 80 miles north of Kiev.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Radiopaque medium used as diagnostic aid.
Pathological processes of the PARATHYROID GLANDS. They usually manifest as hypersecretion or hyposecretion of PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
A form of IODINE deficiency disorders characterized by an enlargement of the THYROID GLAND in a significantly large fraction of a POPULATION GROUP. Endemic goiter is common in mountainous and iodine-deficient areas of the world where the DIET contains insufficient amount of iodine.
Stable iodine atoms that have the same atomic number as the element iodine, but differ in atomic weight. I-127 is the only naturally occurring stable iodine isotope.
Ductless glands that secrete HORMONES directly into the BLOOD CIRCULATION. These hormones influence the METABOLISM and other functions of cells in the body.
The sebaceous glands situated on the inner surface of the eyelids between the tarsal plates and CONJUNCTIVA.
The tear-forming and tear-conducting system which includes the lacrimal glands, eyelid margins, conjunctival sac, and the tear drainage system.
A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1271)
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The abundant submucosal mucous glands in the DUODENUM. These glands secrete BICARBONATE IONS; GLYCOPROTEINS; and PEPSINOGEN II.
Membrane transporters that co-transport two or more dissimilar molecules in the same direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.
Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.
Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.
A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.
Uncontrolled release of radioactive material from its containment. This either threatens to, or does, cause exposure to a radioactive hazard. Such an incident may occur accidentally or deliberately.
Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.
An immunoglobulin G, often found in the blood of hyperthyroid individuals. It stimulates the thyroid for a longer duration than does thyrotoxin and may cause hyperthyroidism in newborns due to placental transmission.
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.
Exocrine glands in animals which secrete scents which either repel or attract other animals, e.g. perianal glands of skunks, anal glands of weasels, musk glands of foxes, ventral glands of wood rats, and dorsal glands of peccaries.
An enlarged THYROID GLAND with at least 50% of the gland situated behind the STERNUM. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the TRACHEA leading to deviation, narrowing, and respiratory symptoms.
Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.
Acute inflammatory disease of the THYROID GLAND due to infections by BACTERIA; FUNGI; or other microorganisms. Symptoms include tender swelling, FEVER, and often with LEUKOCYTOSIS.
An imidazole antithyroid agent. Carbimazole is metabolized to METHIMAZOLE, which is responsible for the antithyroid activity.
The part of a human or animal body connecting the HEAD to the rest of the body.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
Inorganic compounds that contain sodium as an integral part of the molecule.
A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.
Tumors or cancer of the PARATHYROID GLANDS.
An inherited autosomal recessive trait, characterized by peripheral resistance to THYROID HORMONES and the resulting elevation in serum levels of THYROXINE and TRIIODOTHYRONINE. This syndrome is caused by mutations of gene THRB encoding the THYROID HORMONE RECEPTORS BETA in target cells. HYPOTHYROIDISM in these patients is partly overcome by the increased thyroid hormone levels.
Organic compounds containing the radical -CSNH2.
A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)
The species Tursiops truncatus, in the family Delphinidae, characterized by a bottle-shaped beak and slightly hooked broad dorsal fin.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.
Large, branched, specialized sweat glands that empty into the upper portion of a HAIR FOLLICLE instead of directly onto the SKIN.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Congenital structural abnormalities and deformities of the musculoskeletal system.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
Elements of limited time intervals, contributing to particular results or situations.
Cyst due to the occlusion of the duct of a follicle or small gland.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Collection of granular epithelial cells in the uterine muscle beneath the placenta that develop during pregnancy in certain species of animals.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed.
A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.
A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified in DROSOPHILA segmentation genes.
Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.
The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.
The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The largest cartilage of the larynx consisting of two laminae fusing anteriorly at an acute angle in the midline of the neck. The point of fusion forms a subcutaneous projection known as the Adam's apple.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.
Excision of one or more of the parathyroid glands.
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A type of endoplasmic reticulum (ER) where polyribosomes are present on the cytoplasmic surfaces of the ER membranes. This form of ER is prominent in cells specialized for protein secretion and its principal function is to segregate proteins destined for export or intracellular utilization.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
An array of tests used to determine the toxicity of a substance to living systems. These include tests on clinical drugs, foods, and environmental pollutants.
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Glands situated on each side of the prostate that secrete a fluid component of the seminal fluid into the urethra.
Calculi occurring in a salivary gland. Most salivary gland calculi occur in the submandibular gland, but can also occur in the parotid gland and in the sublingual and minor salivary glands.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Branches of the VAGUS NERVE. The superior laryngeal nerves originate near the nodose ganglion and separate into external branches, which supply motor fibers to the cricothyroid muscles, and internal branches, which carry sensory fibers. The RECURRENT LARYNGEAL NERVE originates more caudally and carries efferents to all muscles of the larynx except the cricothyroid. The laryngeal nerves and their various branches also carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.
A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
A malignant epithelial tumor with a glandular organization.
The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario. (1/4177)

The thyroid glands of coho salmon collected at different stages of their anadromous migration exhibited progressive and extensive hyperplasia and hypertrophy. The incidence of overt nodule formation rose from 5% in fish collected in August to 24% in fish collected in October. The histological picture of the goiters was similar to that found in thiourea-treated teleosts and thiouracil-treated mammals. There was a concomitant, significant decrease in serum thyroxine and triiodothyronine values between September and October (thyroxine, 1.0+/-0.3 mug/100 ml and 0.4 mug/100 ml in September and October, respectively; triiodothyronine, 400.3+/-51.6 ng/100 ml and 80.2 ng/100 ml in September and October, respectively) and marked hypertrophy and hyperplasia of thyrotrophs. These data indicate a progressive hypothyroid condition which, although it may be linked to iodide deficiency, may well be enhanced by other environmental factors. The evidence for involvement of other factors is discussed.  (+info)

Characterization of an amphioxus paired box gene, AmphiPax2/5/8: developmental expression patterns in optic support cells, nephridium, thyroid-like structures and pharyngeal gill slits, but not in the midbrain-hindbrain boundary region. (2/4177)

On the basis of developmental gene expression, the vertebrate central nervous system comprises: a forebrain plus anterior midbrain, a midbrain-hindbrain boundary region (MHB) having organizer properties, and a rhombospinal domain. The vertebrate MHB is characterized by position, by organizer properties and by being the early site of action of Wnt1 and engrailed genes, and of genes of the Pax2/5/8 subfamily. Wada and others (Wada, H., Saiga, H., Satoh, N. and Holland, P. W. H. (1998) Development 125, 1113-1122) suggested that ascidian tunicates have a vertebrate-like MHB on the basis of ascidian Pax258 expression there. In another invertebrate chordate, amphioxus, comparable gene expression evidence for a vertebrate-like MHB is lacking. We, therefore, isolated and characterized AmphiPax2/5/8, the sole member of this subfamily in amphioxus. AmphiPax2/5/8 is initially expressed well back in the rhombospinal domain and not where a MHB would be expected. In contrast, most of the other expression domains of AmphiPax2/5/8 correspond to expression domains of vertebrate Pax2, Pax5 and Pax8 in structures that are probably homologous - support cells of the eye, nephridium, thyroid-like structures and pharyngeal gill slits; although AmphiPax2/5/8 is not transcribed in any structures that could be interpreted as homologues of vertebrate otic placodes or otic vesicles. In sum, the developmental expression of AmphiPax2/5/8 indicates that the amphioxus central nervous system lacks a MHB resembling the vertebrate isthmic region. Additional gene expression data for the developing ascidian and amphioxus nervous systems would help determine whether a MHB is a basal chordate character secondarily lost in amphioxus. The alternative is that the MHB is a vertebrate innovation.  (+info)

The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. (3/4177)

The gene encoding the Na/I symporter (NIS) is expressed at high levels only in thyroid follicular cells, where its expression is regulated by the thyroid-stimulating hormone via the second messenger, cyclic AMP (cAMP). In this study, we demonstrate the presence of an enhancer that is located between nucleotides -2264 and -2495 in the 5'-flanking region of the NIS gene and that recapitulates the most relevant aspects of NIS regulation. When fused to either its own or a heterologous promoter, the NIS upstream enhancer, which we call NUE, stimulates transcription in a thyroid-specific and cAMP-dependent manner. The activity of NUE depends on the four most relevant sites, identified by mutational analysis. The thyroid-specific transcription factor Pax8 binds at two of these sites. Mutations that interfere with Pax8 binding also decrease transcriptional activity of the NUE. Furthermore, expression of Pax8 in nonthyroid cells results in transcriptional activation of NUE, strongly suggesting that the paired-domain protein Pax8 plays an important role in NUE activity. The NUE responds to cAMP in both protein kinase A-dependent and -independent manners, indicating that this enhancer could represent a novel type of cAMP responsive element. Such a cAMP response requires Pax8 but also depends on the integrity of a cAMP responsive element (CRE)-like sequence, thus suggesting a functional interaction between Pax8 and factors binding at the CRE-like site.  (+info)

Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. (4/4177)

The c-myb gene encodes a sequence specific transactivator that is required for fetal hematopoiesis, but its potential role in other tissues is less clear because of the early fetal demise of mice with targeted deletions of the c-myb gene and incomplete of knowledge about c-myb's expression pattern. In the hematopoietic system, c-Myb protein acts on target genes whose expression is restricted to individual lineages, despite Myb's presence and role in multiple immature lineages. This suggests that c-Myb actions within different cell type-specific contexts are strongly affected by combinatorial interactions. To consider the possibility of similar c-Myb actions could extend into non-hematopoietic systems in other cell and tissue compartments, we characterized c-myb expression in developing and adult mice using in situ hybridization and correlated this with stage-specific differentiation and mitotic activity. Diverse tissues exhibited strong c-myb expression during development, notably tooth buds, the thyroid primordium, developing trachea and proximal branching airway epithelium, hair follicles, hematopoietic cells, and gastrointestinal crypt epithelial cells. The latter three of these all maintained high expression into adulthood, but with characteristic restriction to immature cell lineages prior to their terminal differentiation. In all sites, during fetal and adult stages, loss of c-Myb expression correlated strikingly with the initiation of terminal differentiation, but not the loss of mitotic activity. Based on these data, we hypothesize that c-Myb's function during cellular differentiation is both an activator of immature gene expression and a suppressor of terminal differentiation in diverse lineages.  (+info)

Measurement of serum TSH in the investigation of patients presenting with thyroid enlargement. (5/4177)

In otherwise euthyroid patients presenting with thyroid enlargement, reduction in serum thyrotrophin (TSH) concentrations measured in a sensitive assay may be a marker of thyroid autonomy and may therefore indicate a benign underlying pathology. We investigated prospectively a cohort of 467 subjects presenting consecutively to our thyroid clinic with nodular or diffuse enlargement of the thyroid. Subjects were divided into those with normal (0.4-5.5 mU/l), low but detectable (0.1-0.39 mU/l) or undetectable (< 0.1 mU/l) serum TSH concentrations. The final pathological diagnosis was defined by fine-needle aspiration cytology and clinical follow-up of at least 2 years or by fine-needle aspiration cytology and histology following surgical treatment. Serum TSH concentrations below normal were found in 75 patients (16.1%), those with low serum TSH results having higher mean free T4 concentrations, were older and were more likely to be female. In those with undetectable serum TSH, no patient had a diagnosis of thyroid neoplasia and in those with low but detectable TSH, thyroid neoplasms were diagnosed in two patients (3.4%). In those with normal serum TSH, 12.0% had a final diagnosis of thyroid neoplasm (p = 0.013). Overall, thyroid malignancy was found in one patient (1.3%) of those with a serum TSH measurement below the normal range and 6.9% of those with normal serum TSH (p < 0.06). Reduction in serum TSH at presentation may identify a group which requires less intensive investigation and follow-up than those without biochemical evidence of thyroid autonomy.  (+info)

RhoA activity is required for fibronectin assembly and counteracts beta1B integrin inhibitory effect in FRT epithelial cells. (6/4177)

FRT thyroid epithelial cells synthesize fibronectin and organize a network of fibronectin fibrils at the basal surface of the cells. Fibronectin fibril formation is enhanced by the overexpression of the ubiquitous beta1A integrin and is inhibited by the expression of the dominant-negative beta1B subunit. We tested the hypotheses that RhoA activity might mediate the integrin-dependent fibronectin fibrillogenesis and might counteract beta1B integrin inhibitory effect. FRT-beta1A cells were transfected with a vector carrying a dominant negative form of RhoA (RhoAN19) or treated with the C3 transferase exoenzyme. Both treatments inhibited fibronectin assembly and caused loss of actin microfilaments and adhesion plaques. On the other hand, FRT-beta1B cells were transfected with the constitutively activated form of RhoA (RhoAV14) or treated with the E. coli cytotoxic necrotizing factor 1, which directly activates RhoA. Either treatment restored microfilament and adhesion plaque assembly and promoted fibronectin fibril organization. A great increase in fibronectin fibril assembly was also obtained by treatment of FRT-beta1B cells with TGF-beta. Our data indicate that RhoA is required to promote fibronectin matrix assembly in FRT cells and that the activation of the signal transduction pathway downstream of RhoA can overcome the inhibitory effect of beta1B integrin.  (+info)

Thyroid volumes and urinary iodine in Swiss school children, 17 years after improved prophylaxis of iodine deficiency. (7/4177)

Salt iodine content in Switzerland was raised from 7.5 to 15 mg per kg in 1980, and since then dietary iodine intake has been considered to be sufficient, even though a slight decrease due to imported food has recently been reported. The aim of this study was to establish normal values for thyroid volumes of school children who can be assumed to have had a sufficient iodine intake all their lifetime. Moreover. the present investigation was undertaken to verify that iodine sufficiency had been achieved equally in two regions each served by one of the two Swiss salt producers. Mean iodine concentration in urine spot samples from school children was 16.1 microg/dl, and it was identical in both the city of Lausanne (n=215) and the city of Solothurn (n=208). Thus it can be stated that in both cities (served by two different salt producers) iodine intake is equal and sufficient. Accordingly, thyroid volumes measured by ultrasound in school children aged 6 to 16 years were the same in both Lausanne (n=202) and Solothurn (n=207). Moreover, the age-adjusted median volumes at the 97th percentiles closely agree with and validate provisional international reference values recently proposed by the World Health Organisation and by the International Council for Control of Iodine Deficiency Disease.  (+info)

Regulation of PiT-1, a sodium-dependent phosphate co-transporter in rat parathyroid glands. (8/4177)

A cDNA encoding an Na+-Pi co-transporter, termed rat PiT-1, has now been isolated from rat parathyroid. Expression of rat PiT-1 in Xenopus oocytes revealed that it possesses Na+-dependent Pi co-transport activity. The amount of PiT-1 mRNA in the parathyroid of vitamin D-deficient rats was reduced compared with that in normal animals, and increased markedly after administration of 1,25-dihydroxyvitamin D3. Furthermore, the abundance of PiT-1 mRNA in the parathyroid was much greater in rats fed a low-Pi diet than in those fed a high-Pi diet. Thus, rat PiT-1 may contribute to the effects of Pi and vitamin D on parathyroid function.  (+info)

There are several types of thyroid neoplasms, including:

1. Thyroid nodules: These are abnormal growths or lumps that can develop in the thyroid gland. Most thyroid nodules are benign (non-cancerous), but some can be malignant (cancerous).
2. Thyroid cancer: This is a type of cancer that develops in the thyroid gland. There are several types of thyroid cancer, including papillary, follicular, and medullary thyroid cancer.
3. Thyroid adenomas: These are benign tumors that develop in the thyroid gland. They are usually non-cancerous and do not spread to other parts of the body.
4. Thyroid cysts: These are fluid-filled sacs that can develop in the thyroid gland. They are usually benign and do not cause any symptoms.

Thyroid neoplasms can be caused by a variety of factors, including genetic mutations, exposure to radiation, and certain medical conditions, such as thyroiditis (inflammation of the thyroid gland).

Symptoms of thyroid neoplasms can include:

* A lump or swelling in the neck
* Pain in the neck or throat
* Difficulty swallowing or breathing
* Hoarseness or voice changes
* Weight loss or fatigue

Diagnosis of thyroid neoplasms usually involves a combination of physical examination, imaging tests (such as ultrasound or CT scans), and biopsies. Treatment depends on the type and severity of the neoplasm, and can include surgery, radiation therapy, and medications.

1. Hypothyroidism: This is a condition where the thyroid gland does not produce enough thyroid hormones. Symptoms can include fatigue, weight gain, dry skin, constipation, and depression.
2. Hyperthyroidism: This is a condition where the thyroid gland produces too much thyroid hormone. Symptoms can include weight loss, anxiety, tremors, and an irregular heartbeat.
3. Thyroid nodules: These are abnormal growths on the thyroid gland that can be benign or cancerous.
4. Thyroid cancer: This is a type of cancer that affects the thyroid gland. There are several types of thyroid cancer, including papillary, follicular, and medullary thyroid cancer.
5. Goiter: This is an enlargement of the thyroid gland that can be caused by a variety of factors, including hypothyroidism, hyperthyroidism, and thyroid nodules.
6. Thyrotoxicosis: This is a condition where the thyroid gland produces too much thyroid hormone, leading to symptoms such as weight loss, anxiety, tremors, and an irregular heartbeat.
7. Thyroiditis: This is an inflammation of the thyroid gland that can cause symptoms such as pain, swelling, and difficulty swallowing.
8. Congenital hypothyroidism: This is a condition where a baby is born without a functioning thyroid gland or with a gland that does not produce enough thyroid hormones.
9. Thyroid cancer in children: This is a type of cancer that affects children and teenagers, usually in the form of papillary or follicular thyroid cancer.
10. Thyroid storm: This is a life-threatening condition where the thyroid gland produces an excessive amount of thyroid hormones, leading to symptoms such as fever, rapid heartbeat, and cardiac arrest.

These are just a few examples of the many conditions that can affect the thyroid gland. It's important to be aware of these conditions and seek medical attention if you experience any symptoms or concerns related to your thyroid health.

There are several types of thyroid nodules, including:

1. Benign nodules: These are the most common type of thyroid nodule and are not cancerous. They can be caused by a variety of factors, such as inflammation, infection, or a benign tumor.
2. Malignant nodules: These are less common than benign nodules and are cancerous. They can grow and spread to other parts of the body if left untreated.
3. Thyroid cancer: This is a type of malignant nodule that is caused by abnormal cell growth within the thyroid gland. There are several types of thyroid cancer, including papillary, follicular, and medullary cancer.

Thyroid nodules can cause a variety of symptoms, including:

1. A lump in the neck
2. Pain in the neck or throat
3. Difficulty swallowing or breathing
4. Hoarseness or changes in voice
5. Enlargement of the thyroid gland (goiter)
6. Weight loss or fatigue

Thyroid nodules can be diagnosed through a variety of tests, including:

1. Physical examination: A healthcare provider will examine the neck and throat to feel for any lumps or abnormalities.
2. Thyroid function tests: These tests measure the levels of thyroid hormones in the blood to determine if the nodule is affecting thyroid function.
3. Imaging tests: Such as ultrasound, CT scan, or MRI scans to visualize the nodule and determine its size and location.
4. Fine needle aspiration biopsy (FNAB): A small sample of the nodule is removed and examined under a microscope to determine if it is benign or malignant.

Treatment for thyroid nodules depends on the type and size of the nodule, as well as the patient's overall health. Some common treatments include:

1. Watchful waiting: Small, non-cancerous nodules may not require immediate treatment and can be monitored with regular check-ups.
2. Thyroid hormone medication: To suppress the growth of the nodule and reduce symptoms.
3. Surgery: To remove the nodule or the entire thyroid gland, depending on the size and location of the nodule.
4. Radioactive iodine ablation: To destroy the nodule with radioactive iodine.
5. Ethanol injection: To shrink the nodule with alcohol injections.

It is important to consult a healthcare provider if you experience any symptoms or lumps in the neck, as thyroid nodules can be cancerous and early detection is key for effective treatment.

1. Hypothyroidism: An underactive thyroid gland can cause the gland to become enlarged as it tries to produce more hormones to compensate for the lack of production.
2. Hyperthyroidism: An overactive thyroid gland can also cause the gland to become enlarged as it produces excessive amounts of hormones.
3. Thyroid nodules: These are abnormal growths within the thyroid gland that can cause the gland to become enlarged.
4. Thyroiditis: This is an inflammation of the thyroid gland that can cause it to become enlarged.
5. Iodine deficiency: Iodine is essential for the production of thyroid hormones, and a lack of iodine in the diet can cause the gland to become enlarged as it tries to produce more hormones.
6. Pituitary gland problems: The pituitary gland, located at the base of the brain, regulates the production of thyroid hormones. Problems with the pituitary gland can cause the thyroid gland to become enlarged.
7. Genetic conditions: Some genetic conditions, such as familial goiter, can cause the thyroid gland to become enlarged.

Symptoms of goiter may include:

* A noticeable lump in the neck
* Difficulty swallowing or breathing
* Hoarseness or vocal cord paralysis
* Fatigue
* Weight gain
* Cold intolerance

Goiter can be diagnosed through a physical examination, blood tests to measure thyroid hormone levels, and imaging studies such as ultrasound or radionuclide scans to evaluate the size and function of the gland. Treatment options for goiter depend on the underlying cause and may include medication, surgery, or radioactive iodine therapy.

Hypothyroidism can be diagnosed through a series of blood tests that measure the levels of thyroid hormones in the body. Treatment typically involves taking synthetic thyroid hormone medication to replace the missing hormones. With proper treatment, most people with hypothyroidism can lead normal, healthy lives.

Hypothyroidism is a relatively common condition, affecting about 4.6 million people in the United States alone. Women are more likely to develop hypothyroidism than men, and it is most commonly diagnosed in middle-aged women.

Some of the symptoms of Hypothyroidism include:

1. Fatigue or tiredness
2. Weight gain
3. Dry skin
4. Constipation
5. Depression or anxiety
6. Memory problems
7. Muscle aches and stiffness
8. Heavy or irregular menstrual periods
9. Pale, dry, or rough skin
10. Hair loss or thinning
11. Cold intolerance
12. Slowed speech and movements

It's important to note that some people may not experience any symptoms at all, especially in the early stages of the condition. However, if left untreated, hypothyroidism can lead to more severe complications such as heart disease, mental health problems, and infertility.

Grave's disease is the most common cause of hyperthyroidism and affects about 1 in 200 people. It can occur at any age but is more common in women and tends to run in families. The exact cause of Grave's disease is not known, but it may be related to a combination of genetic and environmental factors.

Symptoms of Grave's disease can vary from person to person, but common signs include:

* Weight loss
* Nervousness or anxiety
* Irregular heartbeat (palpitations)
* Increased sweating
* Heat intolerance
* Fatigue
* Changes in menstrual cycle in women
* Enlargement of the thyroid gland, known as a goiter
* Bulging eyes (exophthalmos)

Grave's disease can be diagnosed through blood tests and scans. Treatment options include medication to reduce the production of thyroxine, radioactive iodine therapy to destroy part of the thyroid gland, and surgery to remove part or all of the thyroid gland.

It is important to seek medical attention if you experience any symptoms of Grave's disease, as untreated hyperthyroidism can lead to complications such as heart problems, osteoporosis, and eye problems. With proper treatment, most people with Grave's disease can manage their symptoms and lead a normal life.

The most common cause of hyperthyroidism is an autoimmune disorder called Graves' disease, which causes the thyroid gland to produce too much thyroxine (T4) and triiodothyronine (T3). Other causes include inflammation of the thyroid gland (thyroiditis), thyroid nodules, and certain medications.

Symptoms of hyperthyroidism can vary depending on the severity of the condition, but may include:

* Rapid weight loss
* Nervousness or irritability
* Increased heart rate
* Heat intolerance
* Changes in menstrual cycle
* Fatigue
* Muscle weakness
* tremors

If left untreated, hyperthyroidism can lead to more serious complications such as heart problems, bone loss, and eye problems. Treatment options for hyperthyroidism include medications to reduce hormone production, radioactive iodine therapy to destroy part of the thyroid gland, and surgery to remove part or all of the thyroid gland.

In pregnant women, untreated hyperthyroidism can increase the risk of miscarriage, preterm labor, and intellectual disability in the baby. Treatment options for pregnant women with hyperthyroidism are similar to those for non-pregnant adults, but may need to be adjusted to avoid harm to the developing fetus.

It is important for individuals suspected of having hyperthyroidism to seek medical attention as soon as possible to receive proper diagnosis and treatment. Early treatment can help prevent complications and improve quality of life.

Causes: Thyroiditis can be caused by a viral or bacterial infection, autoimmune disorders, or radiation exposure.

Symptoms: Symptoms of thyroiditis may include pain and swelling in the neck, difficulty swallowing, hoarseness, fatigue, weight gain, muscle weakness, and depression.

Types: There are several types of thyroiditis, including subacute thyroiditis, silent thyroiditis, and postpartum thyroiditis.

Diagnosis: Thyroiditis is typically diagnosed through a combination of physical examination, blood tests, and imaging studies such as ultrasound or CT scans.

Treatment: Treatment for thyroiditis usually involves antibiotics to treat any underlying infection, pain relief medication to manage neck swelling and discomfort, and hormone replacement therapy to address hormonal imbalances. In some cases, surgery may be necessary to remove part or all of the affected thyroid gland.

Complications: Untreated thyroiditis can lead to complications such as hypothyroidism (underactive thyroid), hyperthyroidism (overactive thyroid), and thyroid nodules or cancer.

Prevention: Preventing thyroiditis is challenging, but maintaining good overall health, avoiding exposure to radiation, and managing any underlying autoimmune disorders can help reduce the risk of developing the condition.

Prognosis: With proper treatment, most people with thyroiditis experience a full recovery and normalization of thyroid function. However, in some cases, long-term hormone replacement therapy may be necessary to manage persistent hypothyroidism or hyperthyroidism.

Adenocarcinoma, follicular accounts for approximately 15% of all thyroid cancers and is more common in women than men. This type of cancer tends to be less aggressive than other types of thyroid cancer, such as papillary carcinoma, but it can still recur (come back) after treatment and spread to other parts of the body (metastasize).

Treatment options for adenocarcinoma, follicular include surgery to remove the tumor, radioactive iodine therapy, and hormone therapy. The prognosis is generally good for patients with this type of cancer, especially if it is detected early and treated appropriately.

In summary, adenocarcinoma, follicular is a type of thyroid cancer that originates in the glands (follicles) of the thyroid gland. It tends to be less aggressive than other types of thyroid cancer but can still recur and spread to other parts of the body. Treatment options include surgery, radioactive iodine therapy, and hormone therapy.

Nodular goiter is often caused by an imbalance in thyroid hormone production, which can lead to the growth of abnormal cells within the gland. It can also be caused by inflammation or infection of the thyroid gland, as well as by inherited genetic conditions that affect the development of the gland.

Symptoms of nodular goiter can include:

* Enlargement of the neck and swelling in the throat
* Difficulty swallowing or breathing
* Hoarseness or voice changes
* Pain in the neck or throat
* Fatigue, weight gain, or cold intolerance (if hypothyroidism is present)
* Weight loss, nervousness, or heat intolerance (if hyperthyroidism is present)

Diagnosis of nodular goiter typically involves a combination of physical examination, imaging tests such as ultrasound or CT scans, and laboratory tests to evaluate thyroid hormone levels. Treatment depends on the underlying cause and severity of the condition and may include medication to regulate thyroid hormone production, surgery to remove part or all of the thyroid gland, or radioactive iodine therapy to destroy abnormal cells within the gland.

Causes:

1. Genetic mutations: Congenital hypothyroidism can be caused by genetic mutations that affect the structure or function of the thyroid gland. These mutations can be inherited from one or both parents.
2. Thyroid dysgenesis: This occurs when the thyroid gland does not develop properly during fetal development.
3. Autoimmune disorders: In some cases, congenital hypothyroidism can be caused by autoimmune disorders that affect the thyroid gland.

Symptoms:

1. Delayed physical growth and development
2. Intellectual disability
3. Muscle weakness
4. Fatigue
5. Cold intolerance
6. Poor feeding or eating habits
7. Slowed speech development
8. Decreased muscle tone (floppy baby)
9. Yellowish tint to the skin and eyes (jaundice)

Diagnosis:

1. Physical examination
2. Blood tests to measure thyroid hormone levels
3. Ultrasound or scan of the thyroid gland
4. Genetic testing to identify genetic mutations

Treatment:

1. Thyroid hormone replacement therapy: This involves taking synthetic thyroid hormones to replace the missing or underproduced hormones.
2. Monitoring of thyroid hormone levels and adjustment of dosage as needed
3. Regular check-ups with a healthcare provider to monitor growth and development

Prognosis:

If congenital hypothyroidism is diagnosed early and treated appropriately, the prognosis is generally good. With proper treatment, most children with this condition can lead normal lives and achieve their full potential. However, if left untreated, the condition can have serious and long-lasting effects on physical and mental development.

Types of thyroid dysgenesis include:

1. Congenital hypothyroidism (CH): This is the most common type of thyroid dysgenesis and occurs when the thyroid gland fails to develop or produce enough thyroid hormones. CH can be caused by genetic mutations, exposure to certain medications or chemicals during pregnancy, or other unknown factors.
2. Thyroid agenesis: This type of dysgenesis occurs when the thyroid gland fails to develop completely, resulting in a absent or underdeveloped gland. Thyroid agenesis can be caused by genetic mutations or exposure to certain medications or chemicals during pregnancy.
3. Thyroid ectopia: This type of dysgenesis occurs when the thyroid gland develops in an abnormal location, such as in the neck or chest, instead of the normal location in the throat. Thyroid ectopia can be caused by genetic mutations or exposure to certain medications or chemicals during pregnancy.

Symptoms of thyroid dysgenesis can vary depending on the severity and type of disorder, but may include:

* Delayed development and growth
* Intellectual disability
* Speech and language difficulties
* Facial abnormalities, such as a small jaw or protruding tongue
* Difficulty swallowing
* Short stature
* Weight gain or obesity
* Fatigue and lethargy
* Cold intolerance
* Dry skin and hair
* constipation

Diagnosis of thyroid dysgenesis is typically made through a combination of physical examination, medical history, and diagnostic tests such as ultrasound, blood tests, and imaging studies. Treatment for thyroid dysgenesis depends on the specific type and severity of the disorder and may include:

* Thyroid hormone replacement medication to normalize hormone levels
* Surgery to correct physical abnormalities or remove a non-functional thyroid gland
* Speech and language therapy to improve communication skills
* Growth hormone therapy to promote growth and development
* Other supportive care as needed, such as nutritional supplements or psychological counseling.

It is important for individuals with thyroid dysgenesis to receive regular medical care and monitoring throughout their lives to manage symptoms and prevent complications. With appropriate treatment and support, many individuals with thyroid dysgenesis can lead active and fulfilling lives.

The disease is named after Hakama Hashimoto, a Japanese physician who first described it in 1912. It is characterized by the presence of inflammatory cells in the thyroid gland, which can lead to damage to the gland and disrupt its ability to produce thyroid hormones.

The symptoms of Hashimoto's disease are similar to those of hypothyroidism and can include fatigue, weight gain, cold intolerance, dry skin, constipation, and depression. The disease is more common in women than men and typically affects people between the ages of 30 and 50.

Hashimoto's disease is diagnosed based on a combination of symptoms, physical examination findings, and laboratory tests, such as blood tests to measure thyroid hormone levels and an ultrasound or biopsy to examine the thyroid gland. Treatment typically involves replacing missing thyroid hormones with synthetic hormones, but in some cases, surgery may be necessary to remove part or all of the thyroid gland.

While Hashimoto's disease is a chronic condition and cannot be cured, it can be effectively managed with appropriate treatment. With early diagnosis and proper management, most people with Hashimoto's disease can lead normal, healthy lives.

Choristoma is a rare benign tumor that originates from the remnants of the embryonic chorion, which is the outer layer of the placenta. It typically affects the ovary, uterus, or broad ligament in women, and less frequently, the testis, epididymis, or spermatic cord in men.

Characteristics:

Choristomas are usually small (less than 5 cm in diameter) and may be solitary or multiple. They can be spherical, oval, or irregular in shape and are often surrounded by a fibrous capsule. The tumors are typically soft to the touch, with a smooth surface, and may be attached to the surrounding tissue by a stalk-like structure called a peduncle.

Clinical Presentation:

Choristomas are usually asymptomatic and are often incidentally detected during pelvic examination or imaging studies performed for other indications. In some cases, they may cause symptoms such as abdominal pain, pelvic pressure, or bleeding, especially if they rupture or become twisted.

Imaging Features:

Choristomas are typically isointense to the liver on T1-weighted magnetic resonance imaging (MRI) and hyperintense on T2-weighted MRI, indicating high signal intensity on both sequences. They may also show enhancement after contrast administration. On ultrasound, choristomas may appear as hypoechoic masses with irregular margins.

Differential Diagnosis:

The differential diagnosis for choristoma includes other benign and malignant tumors that can occur in the ovary, uterus, or broad ligament, such as fibroma, leiomyoma, endometrial polyp, or cancer. The diagnosis of choristoma is based on a combination of clinical, imaging, and histopathological features.

Treatment:

Choristomas are usually managed conservatively with close follow-up and monitoring to ensure that they do not grow or cause any complications. In rare cases, surgical intervention may be necessary if the tumor becomes symptomatic or if there is concern for malignancy. Complete excision of the choristoma is often difficult due to its extensive involvement with surrounding tissues.

Prognosis:

The prognosis for choristoma is generally good, and most cases are benign and asymptomatic. However, in rare cases, malignant transformation can occur, and the tumor may grow and cause symptoms such as abdominal pain, bleeding, or bowel obstruction. The long-term outlook for patients with choristoma depends on the size, location, and aggressiveness of the tumor, as well as the presence of any underlying medical conditions.

In conclusion, choristoma is a rare benign tumor that can occur in the ovary, uterus, or broad ligament. It typically presents with abdominal pain, bleeding, or other symptoms, and imaging studies are useful in diagnosing and monitoring the tumor. While the prognosis for choristoma is generally good, it is important to consider the possibility of malignant transformation and monitor patients closely for any signs of complications.

Adenomas are caused by genetic mutations that occur in the DNA of the affected cells. These mutations can be inherited or acquired through exposure to environmental factors such as tobacco smoke, radiation, or certain chemicals.

The symptoms of an adenoma can vary depending on its location and size. In general, they may include abdominal pain, bleeding, or changes in bowel movements. If the adenoma becomes large enough, it can obstruct the normal functioning of the affected organ or cause a blockage that can lead to severe health complications.

Adenomas are usually diagnosed through endoscopy, which involves inserting a flexible tube with a camera into the affected organ to visualize the inside. Biopsies may also be taken to confirm the presence of cancerous cells.

Treatment for adenomas depends on their size, location, and severity. Small, non-pedunculated adenomas can often be removed during endoscopy through a procedure called endoscopic mucosal resection (EMR). Larger adenomas may require surgical resection, and in some cases, chemotherapy or radiation therapy may also be necessary.

In summary, adenoma is a type of benign tumor that can occur in glandular tissue throughout the body. While they are not cancerous, they have the potential to become malignant over time if left untreated. Therefore, it is important to seek medical attention if symptoms persist or worsen over time. Early detection and treatment can help prevent complications and improve outcomes for patients with adenomas.

Thyroid pain or discomfort
Difficulty swallowing
Hoarseness
Nausea and vomiting
Fatigue
Loss of appetite
Weight loss
An enlarged thyroid gland (goiter)
A tender, swollen thyroid gland in the neck.

Subacute thyroiditis can cause an overactive thyroid (hyperthyroidism), an underactive thyroid (hypothyroidism), or a combination of both. It is diagnosed with blood tests and ultrasound examination. Treatment for subacute thyroiditis includes medication to manage symptoms, rest, and time. In some cases, surgery may be necessary.

Thyroiditis, subacute definition in the medical field:
An autoimmune condition that causes inflammation of the thyroid gland, often developing after a viral infection; symptoms include thyroid pain, difficulty swallowing, hoarseness, nausea and vomiting, fatigue, loss of appetite, weight loss, an enlarged thyroid gland, and tender, swollen thyroid gland in the neck.

The most common cause of thyrotoxicosis is an overactive thyroid gland, known as hyperthyroidism. This can be caused by a variety of factors, including:

* Graves' disease: An autoimmune disorder that causes the thyroid gland to produce too much thyroid hormone.
* Toxic multinodular goiter: A condition in which one or more nodules in the thyroid gland become overactive and produce excessive amounts of thyroid hormone.
* Thyroid adenoma: A benign tumor of the thyroid gland that can cause hyperthyroidism.
* Thyroid cancer: A malignant tumor of the thyroid gland that can cause hyperthyroidism.

Symptoms of thyrotoxicosis can vary depending on the severity of the condition and the individual affected, but may include:

* Weight loss
* Increased heart rate
* Anxiety
* Sweating
* Tremors
* Nervousness
* Fatigue
* Heat intolerance
* Increased bowel movements
* Muscle weakness

Thyrotoxicosis can be diagnosed through a series of tests, including:

* Blood tests: To measure thyroid hormone levels in the blood.
* Thyroid scan: To visualize the thyroid gland and identify any nodules or tumors.
* Ultrasound: To evaluate the structure of the thyroid gland and detect any abnormalities.

Treatment for thyrotoxicosis depends on the underlying cause, but may include:

* Medications to reduce thyroid hormone production.
* Radioactive iodine therapy to destroy part or all of the thyroid gland.
* Surgery to remove part or all of the thyroid gland.

It is important to note that untreated thyrotoxicosis can lead to complications such as heart problems, osteoporosis, and eye problems, so it is important to seek medical attention if symptoms persist or worsen over time.

Characteristics of Medullary Carcinoma:

1. Location: Medullary carcinoma typically arises in the inner substance of the breast, near the milk ducts and blood vessels.
2. Growth pattern: The cancer cells grow in a nodular or sheet-like pattern, with a clear boundary between the tumor and the surrounding normal tissue.
3. Cellular features: The cancer cells are typically large and polygonal, with prominent nucleoli and a pale, pinkish cytoplasm.
4. Lymphocytic infiltration: There is often a significant amount of lymphocytic infiltration surrounding the tumor, which can give it a "spiculated" or "heterogeneous" appearance.
5. Grade: Medullary carcinoma is generally a low-grade cancer, meaning that the cells are slow-growing and less aggressive than those of other types of breast cancer.
6. Hormone receptors: Medullary carcinoma is often hormone receptor-positive, meaning that the cancer cells have estrogen or progesterone receptors on their surface.
7. Her2 status: The cancer cells are typically Her2-negative, meaning that they do not overexpress the Her2 protein.

Prognosis and Treatment of Medullary Carcinoma:

The prognosis for medullary carcinoma is generally good, as it tends to be a slow-growing and less aggressive type of breast cancer. The 5-year survival rate for medullary carcinoma is around 80-90%.

Treatment for medullary carcinoma typically involves surgery, such as a lumpectomy or mastectomy, followed by radiation therapy and/or hormone therapy. Chemotherapy is sometimes used in addition to these treatments, especially if the cancer has spread to the lymph nodes or other parts of the body.

It's important for women with medullary carcinoma to work closely with their healthcare team to develop a personalized treatment plan that takes into account their unique needs and circumstances. With appropriate treatment, many women with medullary carcinoma can achieve long-term survival and a good quality of life.

There are several subtypes of carcinoma, including:

1. Adenocarcinoma: This type of carcinoma originates in glandular cells, which produce fluids or mucus. Examples include breast cancer, prostate cancer, and colon cancer.
2. Squamous cell carcinoma: This type of carcinoma originates in squamous cells, which are found on the surface layers of skin and mucous membranes. Examples include head and neck cancers, cervical cancer, and anal cancer.
3. Basal cell carcinoma: This type of carcinoma originates in the deepest layer of skin, called the basal layer. It is the most common type of skin cancer and tends to grow slowly.
4. Neuroendocrine carcinoma: This type of carcinoma originates in cells that produce hormones and neurotransmitters. Examples include lung cancer, pancreatic cancer, and thyroid cancer.
5. Small cell carcinoma: This type of carcinoma is a highly aggressive form of lung cancer that spreads quickly to other parts of the body.

The signs and symptoms of carcinoma depend on the location and stage of the cancer. Some common symptoms include:

* A lump or mass
* Pain
* Skin changes, such as a new mole or a change in the color or texture of the skin
* Changes in bowel or bladder habits
* Abnormal bleeding

The diagnosis of carcinoma typically involves a combination of imaging tests, such as X-rays, CT scans, MRI scans, and PET scans, and a biopsy, which involves removing a small sample of tissue for examination under a microscope. Treatment options for carcinoma depend on the location and stage of the cancer and may include surgery, radiation therapy, chemotherapy, or a combination of these.

In conclusion, carcinoma is a type of cancer that originates in epithelial cells and can occur in various parts of the body. Early detection and treatment are important for improving outcomes.

References:

1. American Cancer Society. (2022). Carcinoma. Retrieved from
2. Mayo Clinic. (2022). Carcinoma. Retrieved from
3. MedlinePlus. (2022). Carcinoma. Retrieved from

The exact cause of thyroid crisis is not fully understood, but it is believed to be related to an autoimmune response that triggers the release of excessive amounts of thyroid hormones into the bloodstream. This can lead to a rapid increase in heart rate, cardiac arrhythmias, and other serious complications.

There are two main types of thyroid crisis:

1. Graves' disease-related thyroid crisis: This type is more common and typically affects people with Graves' disease, an autoimmune disorder that causes the thyroid gland to produce too much thyroxine (T4) and triiodothyronine (T3).
2. Toxic multinodular goiter-related thyroid crisis: This type is less common and occurs when multiple nodules in the thyroid gland produce excessive amounts of thyroid hormones.

The symptoms of thyroid crisis can vary depending on the severity of the condition, but they may include:

* Fever
* Vomiting
* Abdominal pain
* Diarrhea
* Heart palpitations
* Rapid heart rate
* Cardiac arrhythmias
* Shortness of breath
* Seizures
* Coma

If you suspect that you or someone else is experiencing thyroid crisis, it is essential to seek medical attention immediately. Treatment typically involves hospitalization and may include the following:

1. Thyroid hormone-blocking medications: These drugs can help reduce the levels of thyroid hormones in the bloodstream and alleviate symptoms.
2. Antibiotics: If there are signs of infection, antibiotics may be prescribed to prevent or treat the infection.
3. Corticosteroids: These medications can help reduce inflammation in the thyroid gland and other parts of the body.
4. Cardiac support: In severe cases, cardiac support such as a pacemaker or defibrillator may be necessary to regulate the heart rhythm.
5. Surgery: In some cases, surgery may be required to remove part or all of the thyroid gland.

Preventing Thyroid Crisis
------------------------

While there is no guaranteed way to prevent thyroid crisis, there are several measures you can take to reduce your risk:

1. Monitor your thyroid function: Regular blood tests can help identify any changes in thyroid hormone levels and allow for early treatment.
2. Manage underlying medical conditions: Conditions such as hypothyroidism, hyperthyroidism, and thyroid nodules can increase the risk of thyroid crisis. Proper management of these conditions can help reduce the risk.
3. Avoid stimulating the thyroid gland: Avoiding activities that stimulate the thyroid gland, such as strenuous exercise or excessive iodine intake, can help reduce the risk of thyroid crisis.
4. Seek prompt medical attention: If you experience any symptoms of thyroid crisis, seek prompt medical attention. Early treatment can help prevent complications and improve outcomes.
5. Be aware of your medications: Certain medications, such as steroids and amiodarone, can increase the risk of thyroid crisis. Be aware of the potential risks and discuss any concerns with your healthcare provider.

Living with Thyroid Crisis
-------------------------

Living with thyroid crisis can be challenging, but there are several resources and support options available to help you manage the condition:

1. Healthcare team: Your healthcare provider is your primary source of information and support. They can provide guidance on managing the condition and address any questions or concerns you may have.
2. Online resources: There are several online resources and support groups available for people with thyroid crisis, such as the American Thyroid Association and the Thyroid Foundation of America. These organizations provide information, resources, and support for people with thyroid conditions.
3. Support groups: Joining a support group can provide a sense of community and help you connect with others who are going through similar experiences.
4. Self-care: Engaging in self-care activities such as exercise, meditation, and relaxation techniques can help manage stress and improve overall well-being.
5. Advocating for yourself: Learning to advocate for yourself and your health is essential when living with thyroid crisis. Be proactive and assertive when communicating with your healthcare provider and loved ones about your needs and concerns.

Conclusion
----------

Thyroid crisis, also known as thyroid storm or thyrotoxic crisis, is a life-threatening condition that requires prompt medical attention. It occurs when the thyroid gland becomes overactive and releases excessive amounts of thyroid hormones into the bloodstream. This can lead to symptoms such as fever, rapid heart rate, and muscle weakness.

If you suspect you or someone you know is experiencing a thyroid crisis, it is essential to seek medical attention immediately. Early treatment can help prevent complications and improve outcomes. Living with thyroid crisis can be challenging, but there are several resources and support options available to help manage the condition. By being proactive and advocating for yourself, you can improve your quality of life and manage this condition effectively.

1. Parotid gland tumors: These are the most common type of salivary gland tumor and can be benign or malignant.
2. Submandibular gland tumors: These are less common than parotid gland tumors but can also be benign or malignant.
3. Sublingual gland tumors: These are rare and usually benign.
4. Warthin's tumor: This is a type of benign tumor that affects the parotid gland.
5. Mucoepidermoid carcinoma: This is a type of malignant tumor that can occur in any of the major salivary glands.
6. Acinic cell carcinoma: This is a rare type of malignant tumor that usually occurs in the parotid gland.
7. Adenoid cystic carcinoma: This is a slow-growing malignant tumor that can occur in any of the major salivary glands.
8. Metastatic tumors: These are tumors that have spread to the salivary glands from another part of the body.

Salivary gland neoplasms can cause a variety of symptoms, including painless lumps or swelling in the neck or face, difficulty swallowing, and numbness or weakness in the face. Treatment options depend on the type and stage of the tumor and may include surgery, radiation therapy, and/or chemotherapy.

In conclusion, salivary gland neoplasms are a diverse group of cancers that affect the salivary glands, and it's important to be aware of the different types, symptoms, and treatment options in order to provide effective care for patients with these tumors.

The term "papillary" refers to the fact that the cancer cells grow in a finger-like shape, with each cell forming a small papilla (bump) on the surface of the tumor. APC is often slow-growing and may not cause any symptoms in its early stages.

APC is generally considered to be less aggressive than other types of cancer, such as ductal carcinoma in situ (DCIS) or invasive breast cancer. However, it can still spread to other parts of the body if left untreated. Treatment options for APC may include surgery, radiation therapy, and/or hormone therapy, depending on the location and stage of the cancer.

It's worth noting that APC is sometimes referred to as "papillary adenocarcinoma" or simply "papillary cancer." However, these terms are often used interchangeably with "adenocarcinoma, papillary" in medical literature and clinical practice.

Example sentence: "The patient was diagnosed with a thyroglossal cyst and underwent surgery to have it removed."

Terms near the end of the list that are related to 'Thyroglossal Cyst' in the medical field include:

- Thyroglossal duct - A structure that normally disappears before birth, but can remain and form a cyst.
- Thyroid gland - A gland located in the neck that produces hormones.
- Laryngeal - Relating to the larynx (voice box).
- Parathyroid gland - A gland located near the thyroid gland that regulates calcium levels in the body.

Symptoms of endocrine tuberculosis may include:

* Swelling in the neck
* Pain in the neck or throat
* Difficulty swallowing
* Hoarseness
* Fever
* Fatigue
* Weight loss

Endocrine tuberculosis can be diagnosed through a combination of physical examination, imaging tests such as ultrasound or CT scans, and laboratory tests to detect the presence of TB bacteria. Treatment typically involves antibiotics to kill the TB bacteria, and thyroid hormone replacement therapy to address any hormonal imbalances caused by the infection. Surgery may also be necessary to remove infected tissue.

Endocrine tuberculosis is relatively rare, but it can be a serious condition if left untreated. It is important for healthcare providers to consider the possibility of endocrine TB when diagnosing and treating patients with thyroid disorders, particularly in areas where TB is common.

Here are some common types of tongue diseases:

1. Oral thrush: A fungal infection that causes white patches on the tongue and inner cheeks.
2. Candidiasis: A fungal infection that can cause redness, irritation, and cracks on the tongue.
3. Lichen planus: An autoimmune condition that leads to inflammation and lesions on the tongue.
4. Leukoplakia: A condition characterized by thick, white patches on the tongue that can be caused by smoking or other irritants.
5. Erthyema migrans: A condition that causes a red, itchy rash on the tongue and other parts of the body.
6. Cancer: Malignant tumors can occur on the tongue, which can be benign or malignant.
7. Melanosis: A condition characterized by dark spots or patches on the tongue.
8. Median rhomboid glossitis: An inflammatory condition that affects the tongue and can cause pain, redness, and swelling.
9. Gingivostomatitis: An inflammation of the gums and tongue that can be caused by bacterial or viral infections.
10. Hairy tongue: A condition characterized by long, hair-like projections on the surface of the tongue.

Treatment for tongue diseases depends on the underlying cause and can range from antifungal medications to surgery. In some cases, tongue diseases may be a sign of an underlying health issue, such as a weakened immune system or a nutrient deficiency. It is essential to consult a healthcare professional for proper diagnosis and treatment.

Some common types of parathyroid diseases include:

1. Hyperparathyroidism: This is a condition in which the parathyroid glands produce too much PTH, leading to high levels of calcium in the blood. It can be caused by a benign tumor or by genetic mutations.
2. Hypoparathyroidism: This is a condition in which the parathyroid glands do not produce enough PTH, leading to low levels of calcium in the blood. It can be caused by autoimmune disorders, radiation therapy, or surgical removal of the parathyroid glands.
3. Parathyroid cancer: This is a rare type of cancer that affects the parathyroid glands. It can cause symptoms such as neck swelling, hoarseness, and difficulty swallowing.
4. Familial isolated hyperparathyroidism (FIH): This is a genetic condition that causes benign tumors to grow on one or more of the parathyroid glands, leading to high levels of calcium in the blood.
5. Parathyroid hormone-secreting pancreatic neuroendocrine tumors (PTH-Secreting PNETs): These are rare tumors that occur in the pancreas and produce excessive amounts of PTH, leading to high levels of calcium in the blood.

Treatment options for parathyroid diseases depend on the specific type and severity of the condition. Surgery is often necessary to remove affected glands or tumors, and medications may be used to manage symptoms such as high blood pressure and kidney stones. In some cases, hormone replacement therapy may be needed to replace missing PTH.

There are several types of salivary gland diseases, including:

1. Parotid gland disease: This type of disease affects the parotid gland, which is located in the jaw and produces saliva to aid in digestion.
2. Sublingual gland disease: This type of disease affects the sublingual gland, which is located under the tongue and produces saliva to keep the mouth moist.
3. Submandibular gland disease: This type of disease affects the submandibular gland, which is located below the jaw and produces saliva to aid in digestion.
4. Mucocele: This is a benign tumor that occurs in the salivary glands and can cause swelling and pain.
5. Mucoceles: These are benign tumors that occur in the salivary glands and can cause swelling and pain.
6. Salivary gland stones: This is a condition where small stones form in the salivary glands and can cause pain and swelling.
7. Salivary gland cancer: This is a type of cancer that affects the salivary glands and can be treated with surgery, radiation therapy, or chemotherapy.
8. Sialadenitis: This is an inflammation of the salivary glands that can cause pain, swelling, and difficulty swallowing.
9. Sialosis: This is a condition where the salivary glands become blocked and cannot produce saliva.
10. Salivary gland cysts: These are fluid-filled sacs that occur in the salivary glands and can cause pain, swelling, and difficulty swallowing.

Salivary gland diseases can be diagnosed through a variety of tests, including imaging studies, biopsies, and blood tests. Treatment for these conditions depends on the specific type of disease and may include medications, surgery, or radiation therapy.

Endemic goiter is most commonly seen in areas where iodine is not readily available in the diet, such as in mountainous regions or coastal areas with limited access to seafood. Iodine is essential for the production of thyroid hormones, and a lack of iodine in the diet can lead to an enlargement of the thyroid gland as the body tries to compensate for the deficiency.

Endemic goiter can be diagnosed through physical examination, imaging tests such as ultrasound or X-ray, and blood tests to measure thyroid hormone levels. Treatment typically involves addressing the underlying iodine deficiency through dietary changes or supplements, and in severe cases, medication to regulate thyroid function.

While endemic goiter is relatively uncommon in developed countries, it remains a significant public health issue in many parts of the world where iodine deficiency is prevalent. In these regions, efforts to improve access to iodized salt and other sources of dietary iodine can help prevent and control endemic goiter.

In summary, endemic goiter is a type of goiter that is common in specific geographic regions or populations and is caused by dietary factors, particularly iodine deficiency. It can lead to hypothyroidism if left untreated and can be diagnosed through physical examination, imaging tests, and blood tests. Treatment typically involves addressing the underlying iodine deficiency through dietary changes or supplements.

The term "papillary" refers to the fact that the cancer cells grow in a finger-like shape, resembling a papilla. The term "follicular" refers to the fact that the cancer cells grow near or within glands (follicles). Both types of cancer are considered relatively low-grade, meaning they tend to grow slowly and do not aggressively invade surrounding tissue.

It's important to note that while these types of carcinomas are generally less aggressive than other types of breast or thyroid cancer, they can still be serious and require prompt medical attention. If you suspect you may have symptoms of papillary or follicular carcinoma, it is essential to consult with a healthcare professional for proper diagnosis and treatment.

The word "myxedema" comes from the Greek words "myxo," meaning "mucus," and "едема," meaning "swelling." This is because the nodules that form in patients with myxedema are typically filled with a thick, mucous-like substance.

Myxedema can affect various parts of the body, including the skin, subcutaneous tissues, and organs. The condition is usually diagnosed through a combination of physical examination, imaging studies such as ultrasound or MRI, and biopsy. Treatment for myxedema typically involves addressing the underlying cause, such as hypothyroidism, and managing any symptoms that arise. In some cases, surgery may be necessary to remove the nodules.

Example sentences:

1. The patient developed a radiation-induced neoplasm in their chest after undergoing radiation therapy for breast cancer.
2. The risk of radiation-induced neoplasms increases with higher doses of radiation exposure, making it crucial to minimize exposure during medical procedures.
3. The oncologist monitored the patient's health closely after their radiation therapy to detect any signs of radiation-induced neoplasms.

Examples and Observations:

Oxyphil adenomas are rare in the small bowel (less than 1% of all small intestinal tumors) but are more common in the duodenum and proximal jejunum. They usually manifest as multiple, submucosal nodules that can vary in size from a few millimeters to several centimeters in diameter. [2]

The presence of oxyphil adenomas in the stomach is rare (less than 1% of all gastric tumors) and most often occurs as multiple, small, submucosal nodules. However, larger adenomas may also be present. [3]

Synonyms: oxyphil cell adenoma; oxyphil cell tumor; oxyphil polyp. [1]

Notes:

* Oxyphil adenomas are often associated with familial adenomatous polyposis (FAP) and Turcot syndrome. [2]

References:

[1] Dorland's Medical Dictionary for Health Care Professionals. © 2008 Saunders, an imprint of Elsevier Inc. All rights reserved. Used with permission.

[2] Oxyphil Adenoma. The Merck Manual of Diagnosis and Therapy, Professional Edition. © 2015 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. All rights reserved. Used with permission.

[3] Oxyphil Adenoma. Gastrointestinal Tumors: benign and malignant tumors of the digestive system, including colorectal cancer, stomach cancer, pancreatic cancer, liver cancer, biliary tract cancer, and soft tissue sarcomas. © 2015 Springer International Publishing Switzerland. All rights reserved. Used with permission.

Some common examples of submandibular gland diseases include:

1. Submandibular gland abscess: A bacterial infection that causes swelling and pain in the submandibular gland.
2. Submandibular gland stones: Small, hard deposits that form in the submandibular gland and can cause pain and difficulty swallowing.
3. Parotid gland tumors: Tumors that develop in the parotid gland, which is located near the submandibular gland and helps to produce saliva.
4. Submandibular gland cysts: Fluid-filled sacs that form in the submandibular gland and can cause swelling and pain.
5. Submandibular gland cancer: A type of cancer that develops in the submandibular gland and can spread to other parts of the body.

Symptoms of substernal goiter may include:

* A visible swelling in the neck or chest
* Pain or discomfort in the neck, throat, or chest
* Difficulty swallowing or breathing
* Hoarseness or voice changes
* Fatigue, weight gain, or cold intolerance

If you suspect that you may have substernal goiter, it is important to seek medical attention. A healthcare professional will perform a physical examination and order diagnostic tests such as blood work and imaging studies (e.g., ultrasound, CT scan) to determine the cause of the condition and develop an appropriate treatment plan.

Treatment for substernal goiter will depend on the underlying cause of the condition. For example, hypothyroidism may be treated with synthetic thyroid hormone replacement therapy, while hyperthyroidism may be treated with medications to reduce thyroid hormone production or surgery to remove part or all of the thyroid gland. Thyroid nodules and cancer may require surgical removal of the affected tissue.

In some cases, substernal goiter may not cause any symptoms and may not require treatment. However, it is important to seek medical attention if you notice any unusual changes in your neck or chest, as early detection and treatment can help prevent complications and improve outcomes.

Symptoms of suppurative thyroiditis may include fever, neck swelling, difficulty swallowing, and shortness of breath. Treatment typically involves antibiotics to clear the infection, as well as drainage of any abscesses that have formed. In some cases, surgical removal of the infected tissue may be necessary.

Thyroiditis, suppurative is a relatively rare condition, and it is often seen in older adults and in people with pre-existing conditions such as diabetes or chronic lung disease. Prompt treatment can help prevent complications and improve outcomes for patients with this condition.

There are different types of hyperplasia, depending on the location and cause of the condition. Some examples include:

1. Benign hyperplasia: This type of hyperplasia is non-cancerous and does not spread to other parts of the body. It can occur in various tissues and organs, such as the uterus (fibroids), breast tissue (fibrocystic changes), or prostate gland (benign prostatic hyperplasia).
2. Malignant hyperplasia: This type of hyperplasia is cancerous and can invade nearby tissues and organs, leading to serious health problems. Examples include skin cancer, breast cancer, and colon cancer.
3. Hyperplastic polyps: These are abnormal growths that occur in the gastrointestinal tract and can be precancerous.
4. Adenomatous hyperplasia: This type of hyperplasia is characterized by an increase in the number of glandular cells in a specific organ, such as the colon or breast. It can be a precursor to cancer.

The symptoms of hyperplasia depend on the location and severity of the condition. In general, they may include:

* Enlargement or swelling of the affected tissue or organ
* Pain or discomfort in the affected area
* Abnormal bleeding or discharge
* Changes in bowel or bladder habits
* Unexplained weight loss or gain

Hyperplasia is diagnosed through a combination of physical examination, imaging tests such as ultrasound or MRI, and biopsy. Treatment options depend on the underlying cause and severity of the condition, and may include medication, surgery, or other interventions.

Types of Parathyroid Neoplasms: There are several types of parathyroid neoplasms, including:

1. Adenoma: A benign tumor that is the most common type of parathyroid neoplasm. It usually causes hyperparathyroidism, a condition characterized by high levels of calcium in the blood.
2. Hyperplasia: A condition where the parathyroid glands become enlarged and produce excessive amounts of parathyroid hormone, leading to hyperparathyroidism.
3. Carcinoma: A malignant tumor that is rare and usually occurs in patients with a history of radiation exposure or familial adenomatous polyposis (FAP).

Symptoms of Parathyroid Neoplasms: The symptoms of parathyroid neoplasms can vary depending on the type and size of the tumor. Some common symptoms include:

1. Hyperparathyroidism: High levels of calcium in the blood, which can lead to symptoms such as fatigue, nausea, vomiting, and weakness.
2. Enlarged thyroid gland: A swelling in the neck due to an enlarged thyroid gland, which can cause difficulty swallowing or breathing.
3. Pain in the neck or throat: A painful lump in the neck or throat that can be caused by a tumor pressing on nearby structures.
4. Fever: An elevated body temperature that can occur if the tumor becomes infected or inflamed.
5. Weight loss: Unexplained weight loss, which can occur if the tumor is secreting excessive amounts of parathyroid hormone.

Diagnosis of Parathyroid Neoplasms: The diagnosis of parathyroid neoplasms typically involves a combination of imaging studies and laboratory tests. Some common diagnostic procedures include:

1. Ultrasound: A non-invasive imaging technique that uses high-frequency sound waves to produce images of the thyroid gland and any tumors present.
2. Thyroid scan: A nuclear medicine test that involves injecting a small amount of radioactive material into the bloodstream to visualize the thyroid gland and any tumors present.
3. Calcium levels: Blood tests to measure calcium levels, which can be elevated in hyperparathyroidism.
4. Parathyroid hormone (PTH) level: A blood test to measure PTH levels, which can be elevated in hyperparathyroidism.
5. Biopsy: A procedure that involves removing a small sample of tissue from the thyroid gland and examining it under a microscope for cancer cells.

Treatment of Parathyroid Neoplasms: The treatment of parathyroid neoplasms depends on the type and size of the tumor, as well as the severity of hyperparathyroidism. Some common treatments include:

1. Surgery: The primary treatment for parathyroid neoplastic diseases is surgical removal of the affected parathyroid gland(s).
2. Radioactive iodine ablation: A therapy that involves taking a small dose of radioactive iodine to destroy any remaining thyroid tissue that may be producing excessive amounts of thyroid hormones.
3. Thyroid hormone medications: Medications that are used to control hyperthyroidism and hypothyroidism.
4. Calcium and vitamin D supplements: Medications that are used to treat hypocalcemia and vitamin D deficiency.
5. Monitoring: Regular monitoring of calcium levels, PTH levels, and symptoms is important to ensure that the treatment is effective and to detect any recurrences or complications.

Prognosis: The prognosis for patients with parathyroid neoplasms depends on the type and size of the tumor, as well as the severity of hyperparathyroidism. In general, the prognosis is good for patients who undergo surgical removal of the affected gland(s), but it may be poorer for those with more advanced or invasive tumors.

Complications: Complications of parathyroid neoplasms include:

1. Hyperparathyroidism: Excessive production of PTH can lead to hyperthyroidism, hypocalcemia, and other complications.
2. Recurrence: There is a risk of recurrence after surgical removal of the affected gland(s).
3. Spread of disease: In rare cases, parathyroid tumors can spread to other parts of the body (such as the lymph nodes or bones) and cause metastatic disease.
4. Hypoparathyroidism: Removal of all four parathyroid glands can lead to hypoparathyroidism, which can be life-threatening if not treated promptly.
5. Pancreatitis: Some studies have suggested that there may be an increased risk of pancreatitis in patients with parathyroid neoplasms.

The symptoms of thyroid hormone resistance syndrome can vary depending on the severity of the mutation and may include:

1. Hypoglycemia (low blood sugar)
2. Growth retardation
3. Congenital hypothyroidism (CH)
4. Neonatal hypothyroidism (NH)
5. Cretinism
6. Mental retardation
7. Developmental delays
8. Short stature
9. Coarse facial features
10. Elevated TSH levels

The diagnosis of thyroid hormone resistance syndrome is based on a combination of clinical findings, laboratory tests, and genetic analysis. Treatment options for this condition include:

1. Thyroid hormone replacement therapy to normalize metabolic function and growth.
2. Monitoring TSH levels to ensure that the thyroid hormone dosage is appropriate.
3. Management of associated symptoms such as hypoglycemia or growth retardation.
4. Genetic counseling to discuss the risks of passing on the condition to future generations.

The prognosis for individuals with thyroid hormone resistance syndrome varies depending on the severity of the condition and the presence of any additional health problems. Early diagnosis and appropriate treatment can improve growth and developmental outcomes, but some individuals may experience persistent health issues or intellectual disability.

The cancer cells of this type are thought to arise from abnormalities in the cells that line the ducts of the salivary glands. These abnormal cells grow and divide uncontrollably, forming a mass that can obstruct the flow of saliva and cause symptoms such as pain, swelling, and difficulty eating or speaking.

Mucoepidermoid carcinoma is typically diagnosed with a combination of imaging studies, such as CT scans, MRI, and PET scans, and a biopsy, where a sample of tissue is removed from the tumor and examined under a microscope for cancer cells. Treatment typically involves surgery to remove the tumor, followed by radiation therapy and/or chemotherapy to kill any remaining cancer cells.

Prognosis for this type of cancer is generally good if it is diagnosed early and treated promptly, but it can be challenging to treat if it has spread to other parts of the body.

There are several types of MEN, including:

1. Multiple Endocrine Neoplasia Type 1 (MEN1): This is the most common type of MEN and is caused by mutations in the MEN1 gene, which is located on chromosome 11. This condition typically affects the parathyroid glands, pancreas, and pituitary gland.
2. Multiple Endocrine Neoplasia Type 2A (MEN2A): This type of MEN is caused by mutations in the RET gene, which is located on chromosome 10. It typically affects the parathyroid glands, pancreas, and pituitary gland, as well as other endocrine glands such as the thyroid gland.
3. Multiple Endocrine Neoplasia Type 2B (MEN2B): This type of MEN is also caused by mutations in the RET gene, but it typically affects only the parathyroid glands and the pituitary gland.

The symptoms of MEN vary depending on the specific type and the affected glands. Common symptoms include:

* Hyperparathyroidism (too much parathyroid hormone): This can lead to symptoms such as high blood calcium levels, kidney stones, and bone disease.
* Thyroid cancer: People with MEN are at an increased risk of developing thyroid cancer, particularly papillary thyroid cancer.
* Pancreatic neuroendocrine tumors (PNETs): These are tumors that develop in the pancreas and can produce excess hormones that can cause a variety of symptoms, such as diabetes, high blood sugar, and stomach problems.
* Pituitary tumors: Tumors in the pituitary gland can cause a variety of symptoms related to hormone imbalances, such as excess growth hormone or prolactin.

If you have been diagnosed with MEN, your healthcare provider will recommend regular monitoring and testing to detect any signs of tumors or hormone imbalances early on. Treatment may involve surgery, medication, or other therapies, depending on the specific symptoms and the type of MEN you have.

It is important to note that MEN is a rare condition, and it can be difficult to diagnose. It is important to work with a healthcare provider who has experience in treating patients with MEN. With appropriate treatment, many people with MEN can lead normal, healthy lives.

Some examples of musculoskeletal abnormalities include:

- Carpal tunnel syndrome: Compression of the median nerve in the wrist that can cause numbness, tingling, and weakness in the hand and arm.

- Kyphosis: An exaggerated curvature of the spine, often resulting from osteoporosis or other conditions that affect the bones.

- Osteoarthritis: Wear and tear on the joints, leading to pain, stiffness, and limited mobility.

- Clubfoot: A congenital deformity in which the foot is turned inward or outward.

- Scoliosis: An abnormal curvature of the spine that can be caused by genetics, injury, or other factors.

Musculoskeletal abnormalities can be diagnosed through physical examination, imaging tests such as X-rays and MRIs, and other diagnostic procedures. Treatment options vary depending on the specific condition but may include medication, physical therapy, braces or orthotics, or surgery in severe cases.

The submandibular glands are located beneath the jawbone and produce saliva to aid in digestion. When abnormal cells grow in these glands, it can lead to various types of tumors, including benign and malignant ones. Submandibular gland neoplasms refer to any type of tumor or growth that develops in the submandibular glands.

Types of Submandibular Gland Neoplasms:

There are several types of submandibular gland neoplasms, including:

1. Pleomorphic adenoma: This is the most common type of benign tumor that develops in the submandibular glands. It can grow slowly over time and may or may not cause symptoms.
2. Warthin's tumor: This is a type of benign tumor that is more common in older adults. It typically grows slowly and does not spread to other parts of the body.
3. Mucoepidermoid carcinoma: This is a type of malignant tumor that can grow quickly and spread to other parts of the body. It is rare and usually occurs in people under the age of 40.
4. Acinic cell carcinoma: This is a rare type of malignant tumor that typically affects children and young adults. It grows slowly and has a good prognosis if treated early.
5. Adenoid cystic carcinoma: This is a rare type of malignant tumor that can grow slowly over time and invade surrounding tissues.

Symptoms of Submandibular Gland Neoplasms:

The symptoms of submandibular gland neoplasms vary depending on the size and location of the tumor. Some common symptoms include:

1. Swelling in the neck or jaw
2. Pain or tenderness in the neck, jaw, or ear
3. Difficulty swallowing or eating
4. Numbness or weakness in the face
5. Persistent earaches or hearing loss

Diagnosis of Submandibular Gland Neoplasms:

To diagnose a submandibular gland neoplasm, your doctor will begin with a physical examination and ask questions about your symptoms and medical history. They may also order one or more of the following tests:

1. Fine needle aspiration biopsy: This test involves inserting a thin needle into the tumor to collect a sample of cells for testing.
2. Imaging tests: Such as CT scans, MRI scans, and PET scans to visualize the size and location of the tumor.
3. Endoscopy: A flexible tube with a light and camera on the end is inserted through the mouth or nose to examine the inside of the mouth and throat.
4. Blood tests: To check for certain substances in the blood that can indicate the presence of a neoplasm.

Treatment of Submandibular Gland Neoplasms:

The treatment of submandibular gland neoplasms depends on the type, size, location, and stage of the tumor. Some common treatment options include:

1. Surgery: To remove the tumor and some surrounding tissue.
2. Radiation therapy: High-energy beams to kill cancer cells.
3. Chemotherapy: Drugs to kill cancer cells.
4. Observation: Monitoring the tumor with regular checkups and imaging tests to see if it grows or changes.
5. Endocrine therapy: Medications to reduce the production of hormones that can stimulate the growth of the tumor.

Prognosis of Submandibular Gland Neoplasms:

The prognosis for submandibular gland neoplasms varies based on the type and stage of the tumor. In general, benign tumors have a good prognosis and are unlikely to spread or recur. Malignant tumors, on the other hand, can be more aggressive and may have a poorer prognosis if left untreated.

Prevention of Submandibular Gland Neoplasms:

There is no known way to prevent submandibular gland neoplasms entirely, but early detection and treatment can improve outcomes. Regular dental checkups and self-exams can help identify any abnormalities or changes in the submandibular gland early on. Additionally, avoiding risk factors such as smoking and excessive alcohol consumption can reduce the likelihood of developing a malignant tumor.

Conclusion:

Submandibular gland neoplasms are rare but can be serious conditions that require prompt diagnosis and treatment. While the prognosis varies based on the type and stage of the tumor, early detection and intervention can improve outcomes. Understanding the causes, risk factors, symptoms, diagnosis, treatment options, and prevention strategies for submandibular gland neoplasms can help individuals take a more proactive approach to their health and seek medical attention if they experience any unusual symptoms in the neck or jaw area.

Body weight is an important health indicator, as it can affect an individual's risk for certain medical conditions, such as obesity, diabetes, and cardiovascular disease. Maintaining a healthy body weight is essential for overall health and well-being, and there are many ways to do so, including a balanced diet, regular exercise, and other lifestyle changes.

There are several ways to measure body weight, including:

1. Scale: This is the most common method of measuring body weight, and it involves standing on a scale that displays the individual's weight in kg or lb.
2. Body fat calipers: These are used to measure body fat percentage by pinching the skin at specific points on the body.
3. Skinfold measurements: This method involves measuring the thickness of the skin folds at specific points on the body to estimate body fat percentage.
4. Bioelectrical impedance analysis (BIA): This is a non-invasive method that uses electrical impulses to measure body fat percentage.
5. Dual-energy X-ray absorptiometry (DXA): This is a more accurate method of measuring body composition, including bone density and body fat percentage.

It's important to note that body weight can fluctuate throughout the day due to factors such as water retention, so it's best to measure body weight at the same time each day for the most accurate results. Additionally, it's important to use a reliable scale or measuring tool to ensure accurate measurements.

The exact cause of follicular cysts is not known, but they may be related to hormonal changes, genetic factors, or blockages within the hair follicle. Treatment options include observation, antibiotics, and surgical removal if the cyst becomes inflamed or infected.

A Follicular Cyst is a benign cystic lesion that forms in the scalp or face and typically arises from the hair follicle. They are usually small, soft to the touch, and painless unless they become inflamed or infected.

Follicular cysts are more common in women than men, and often appear during childhood or adolescence. Although their exact cause is unknown, they may be related to hormonal changes, genetic factors, or blockages within the hair follicle.

Small, soft, painless cysts that form on the scalp or face are usually Follicular Cysts, which are benign and do not produce any symptoms unless they become inflamed or infected. They appear more frequently in women than men and often develop during childhood or adolescence. Their exact cause is unknown but may be related to hormonal fluctuations, genetic factors, or blockages within the hair follicle.

There are many different types of cysts that can occur in the body, including:

1. Sebaceous cysts: These are small, usually painless cysts that form in the skin, particularly on the face, neck, or torso. They are filled with a thick, cheesy material and can become inflamed or infected.
2. Ovarian cysts: These are fluid-filled sacs that form on the ovaries. They are common in women of childbearing age and can cause pelvic pain, bloating, and other symptoms.
3. Kidney cysts: These are fluid-filled sacs that form in the kidneys. They are usually benign but can cause problems if they become large or infected.
4. Dermoid cysts: These are small, usually painless cysts that form in the skin or organs. They are filled with skin cells, hair follicles, and other tissue and can become inflamed or infected.
5. Pilar cysts: These are small, usually painless cysts that form on the scalp. They are filled with a thick, cheesy material and can become inflamed or infected.
6. Epidermoid cysts: These are small, usually painless cysts that form just under the skin. They are filled with a thick, cheesy material and can become inflamed or infected.
7. Mucous cysts: These are small, usually painless cysts that form on the fingers or toes. They are filled with a clear, sticky fluid and can become inflamed or infected.
8. Baker's cyst: This is a fluid-filled cyst that forms behind the knee. It can cause swelling and pain in the knee and is more common in women than men.
9. Tarlov cysts: These are small, fluid-filled cysts that form in the spine. They can cause back pain and other symptoms, such as sciatica.
10. ganglion cysts: These are noncancerous lumps that form on the joints or tendons. They are filled with a thick, clear fluid and can cause pain, swelling, and limited mobility.

It's important to note that this is not an exhaustive list and there may be other types of cysts that are not included here. If you suspect that you have a cyst, it's always best to consult with a healthcare professional for proper diagnosis and treatment.

1. Parvovirus (Parvo): A highly contagious viral disease that affects dogs of all ages and breeds, causing symptoms such as vomiting, diarrhea, and severe dehydration.
2. Distemper: A serious viral disease that can affect dogs of all ages and breeds, causing symptoms such as fever, coughing, and seizures.
3. Rabies: A deadly viral disease that affects dogs and other animals, transmitted through the saliva of infected animals, and causing symptoms such as aggression, confusion, and paralysis.
4. Heartworms: A common condition caused by a parasitic worm that infects the heart and lungs of dogs, leading to symptoms such as coughing, fatigue, and difficulty breathing.
5. Ticks and fleas: These external parasites can cause skin irritation, infection, and disease in dogs, including Lyme disease and tick-borne encephalitis.
6. Canine hip dysplasia (CHD): A genetic condition that affects the hip joint of dogs, causing symptoms such as arthritis, pain, and mobility issues.
7. Osteosarcoma: A type of bone cancer that affects dogs, often diagnosed in older dogs and causing symptoms such as lameness, swelling, and pain.
8. Allergies: Dog allergies can cause skin irritation, ear infections, and other health issues, and may be triggered by environmental factors or specific ingredients in their diet.
9. Gastric dilatation-volvulus (GDV): A life-threatening condition that occurs when a dog's stomach twists and fills with gas, causing symptoms such as vomiting, pain, and difficulty breathing.
10. Cruciate ligament injuries: Common in active dogs, these injuries can cause joint instability, pain, and mobility issues.

It is important to monitor your dog's health regularly and seek veterinary care if you notice any changes or abnormalities in their behavior, appetite, or physical condition.

There are two main types of hyperparathyroidism: primary and secondary. Primary hyperparathyroidism is caused by a benign tumor in one of the parathyroid glands, while secondary hyperparathyroidism is caused by another condition that leads to overproduction of PTH, such as kidney disease or vitamin D deficiency.

Symptoms of hyperparathyroidism can include:

* High blood calcium levels
* Bone loss or osteoporosis
* Kidney stones
* Pancreatitis (inflammation of the pancreas)
* Hyperthyroidism (an overactive thyroid gland)
* Fatigue
* Weakness
* Nausea and vomiting
* Abdominal pain
* Headaches

Treatment for hyperparathyroidism usually involves surgery to remove the affected parathyroid gland or glands. In some cases, medications may be used to manage symptoms before surgery. It is important for individuals with hyperparathyroidism to receive prompt medical attention, as untreated hyperparathyroidism can lead to serious complications such as heart disease and kidney failure.

Multiple primary neoplasms can arise in different organs or tissues throughout the body, such as the breast, colon, prostate, lung, or skin. Each tumor is considered a separate entity, with its own unique characteristics, including size, location, and aggressiveness. Treatment for multiple primary neoplasms typically involves surgery, chemotherapy, radiation therapy, or a combination of these modalities.

The diagnosis of multiple primary neoplasms can be challenging due to the overlapping symptoms and radiological findings between the different tumors. Therefore, it is essential to have a thorough clinical evaluation and diagnostic workup to rule out other possible causes of the symptoms and confirm the presence of multiple primary neoplasms.

Multiple primary neoplasms are more common than previously thought, with an estimated prevalence of 2% to 5% in some populations. The prognosis for patients with multiple primary neoplasms varies depending on the location, size, and aggressiveness of each tumor, as well as the patient's overall health status.

It is important to note that multiple primary neoplasms are not the same as metastatic cancer, in which a single primary tumor spreads to other parts of the body. Multiple primary neoplasms are distinct tumors that arise independently from different primary sites within the body.

Examples of autoimmune diseases include:

1. Rheumatoid arthritis (RA): A condition where the immune system attacks the joints, leading to inflammation, pain, and joint damage.
2. Lupus: A condition where the immune system attacks various body parts, including the skin, joints, and organs.
3. Hashimoto's thyroiditis: A condition where the immune system attacks the thyroid gland, leading to hypothyroidism.
4. Multiple sclerosis (MS): A condition where the immune system attacks the protective covering of nerve fibers in the central nervous system, leading to communication problems between the brain and the rest of the body.
5. Type 1 diabetes: A condition where the immune system attacks the insulin-producing cells in the pancreas, leading to high blood sugar levels.
6. Guillain-Barré syndrome: A condition where the immune system attacks the nerves, leading to muscle weakness and paralysis.
7. Psoriasis: A condition where the immune system attacks the skin, leading to red, scaly patches.
8. Crohn's disease and ulcerative colitis: Conditions where the immune system attacks the digestive tract, leading to inflammation and damage to the gut.
9. Sjögren's syndrome: A condition where the immune system attacks the glands that produce tears and saliva, leading to dry eyes and mouth.
10. Vasculitis: A condition where the immune system attacks the blood vessels, leading to inflammation and damage to the blood vessels.

The symptoms of autoimmune diseases vary depending on the specific disease and the organs or tissues affected. Common symptoms include fatigue, fever, joint pain, skin rashes, and swollen lymph nodes. Treatment for autoimmune diseases typically involves medication to suppress the immune system and reduce inflammation, as well as lifestyle changes such as dietary changes and stress management techniques.

The term "calculus" refers to a small, hard deposit that has formed within the salivary gland ducts or sacs. These deposits are made up of crystallized minerals, such as calcium phosphate, ammonium urate, or magnesium ammonium phosphate, which can accumulate in the salivary glands over time due to a variety of factors.

Salivary gland calculi are relatively rare, but they can be quite painful and can cause significant discomfort and difficulty for patients. Treatment options for salivary gland calculi include medications to dissolve the calculi, surgery to remove the calculi, or sialography, a minimally invasive procedure that uses dye to visualize the salivary glands and locate any blockages or stones.

The medical field recognizes several types of salivary gland calculi, including:

1. Parotid calculi: These are the most common type of salivary gland calculus and form in the parotid gland, which is located in front of the ear.
2. Submandibular calculi: These form in the submandibular gland, which is located under the tongue.
3. Sublingual calculi: These form in the sublingual gland, which is located under the tongue.
4. Warthin's tumor: This is a rare type of salivary gland calculus that forms in the parotid gland and can be benign or malignant.

In summary, salivary gland calculi are small, hard deposits that can form within the salivary glands, causing pain, swelling, and difficulty opening the mouth. Treatment options include medications to dissolve the calculi, surgery to remove the calculi, or sialography. The medical field recognizes several types of salivary gland calculi, including parotid, submandibular, sublingual, and Warthin's tumor.

Rare diseases can be caused by genetic mutations, infections, allergies, or other factors, and they can affect any part of the body. Some examples of rare diseases include cystic fibrosis, Huntington's disease, sickle cell anemia, and Tay-Sachs disease.

Because rare diseases are so uncommon, they often receive less attention and funding for research and treatment than more common conditions. However, there are organizations and resources available to support individuals with rare diseases and their families. These include patient advocacy groups, research foundations, and specialized healthcare providers.

Some of the key features of rare diseases include:

1. Low prevalence: Rare diseases affect a small percentage of the population, typically less than 1%.
2. Limited understanding: Many rare diseases are not well understood, and their causes and mechanisms are not yet fully understood.
3. Lack of effective treatments: There may be limited or no effective treatments for rare diseases, leading to a significant impact on quality of life.
4. High cost: Treatment for rare diseases can be expensive, and the financial burden can be significant for families and individuals affected.
5. Limited access to care: Due to the rarity of the disease, individuals may have limited access to specialized healthcare providers and resources.

Rare diseases are a significant public health concern, as they affect millions of people worldwide and can have a profound impact on their quality of life. There is a need for increased research, advocacy, and support for individuals with rare diseases and their families.

Adenocarcinoma is a term used to describe a variety of different types of cancer that arise in glandular tissue, including:

1. Colorectal adenocarcinoma (cancer of the colon or rectum)
2. Breast adenocarcinoma (cancer of the breast)
3. Prostate adenocarcinoma (cancer of the prostate gland)
4. Pancreatic adenocarcinoma (cancer of the pancreas)
5. Lung adenocarcinoma (cancer of the lung)
6. Thyroid adenocarcinoma (cancer of the thyroid gland)
7. Skin adenocarcinoma (cancer of the skin)

The symptoms of adenocarcinoma depend on the location of the cancer and can include:

1. Blood in the stool or urine
2. Abdominal pain or discomfort
3. Changes in bowel habits
4. Unusual vaginal bleeding (in the case of endometrial adenocarcinoma)
5. A lump or thickening in the breast or elsewhere
6. Weight loss
7. Fatigue
8. Coughing up blood (in the case of lung adenocarcinoma)

The diagnosis of adenocarcinoma is typically made through a combination of imaging tests, such as CT scans, MRI scans, and PET scans, and a biopsy, which involves removing a sample of tissue from the affected area and examining it under a microscope for cancer cells.

Treatment options for adenocarcinoma depend on the location of the cancer and can include:

1. Surgery to remove the tumor
2. Chemotherapy, which involves using drugs to kill cancer cells
3. Radiation therapy, which involves using high-energy X-rays or other particles to kill cancer cells
4. Targeted therapy, which involves using drugs that target specific molecules on cancer cells to kill them
5. Immunotherapy, which involves using drugs that stimulate the immune system to fight cancer cells.

The prognosis for adenocarcinoma is generally good if the cancer is detected and treated early, but it can be more challenging to treat if the cancer has spread to other parts of the body.

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Andreeva P (2014). "[Thyroid gland and fertility]". Akusherstvo I Ginekologiia. 53 (7): 18-23. PMID 25675618. Tersigni C, ... clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review" (PDF). ... General factors Diabetes mellitus, thyroid disorders, undiagnosed and untreated coeliac disease, adrenal disease Hypothalamic- ... pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased ...
Teratoma of the thyroid gland. Black grain mycetoma due to Madurella mycetomi: a case report from the East Central State of ... Suseelan, AV; Gupta, IM; Viswanathan, V; Udekwu, FA (1976). "Teratoma of the thyroid gland". International Surgery. 62 (11-12 ...
Wolff, J (1998). "Perchlorate and the thyroid gland". Pharmacological Reviews. 50 (1): 89-105. PMID 9549759. Barzilai, D; ... accumulated in the thyroid as a result of many different disruptions in the further metabolism of iodide in the thyroid gland. ... perchlorate begins to temporarily inhibit the thyroid gland's ability to absorb iodine from the bloodstream ("iodide uptake ... "The Effect of Short-Term Low-Dose Perchlorate on Various Aspects of Thyroid Function". Thyroid. 10 (8): 659-63. doi:10.1089/ ...
Wolff, J (1998). "Perchlorate and the thyroid gland". Pharmacological Reviews. 50 (1): 89-105. PMID 9549759. Barzilai, D; ... accumulated in the thyroid as a result of many different disruptions in the further metabolism of iodide in the thyroid gland. ... perchlorate begins to temporarily inhibit the thyroid gland's ability to absorb iodine from the bloodstream ("iodide uptake ... "The Effect of Short-Term Low-Dose Perchlorate on Various Aspects of Thyroid Function". Thyroid. 10 (8): 659-63. doi:10.1089/ ...
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Tumors of the Thyroid Gland. Volume 4 of Atlas of tumor pathology: Second series. William A. Meissner, Shields Warren. Armed ... Salivary Gland Tumors. Neil W. Swinton, Shields Warren. (1938). Tumors of Dermal Appendages. Harvard University. Cancer ... Warren's research focused primarily on cancer, thyroid disorders, diabetes, and atomic radiation. During his cancer research in ...
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In this volume, he clearly showed that the removing of the thyroid gland from dogs was fatal, and later showed that the ... Iason, Alfred Herbert (1946). The Thyroid Gland in Medical History ... Froben Press. Portals: biology Germany (CS1: Julian- ... Subsequently, he successfully used thyroid extract to treat humans. Untersuchungen zur Physiologie des Nervensystems mit ... injection of animal extract or thyroid transplantation can prevent death. ...
"Wölfler's gland": An accessory thyroid gland. "Wölfler's operation": Operation of gastroenterostomy. described in a paper ... Wölfler is remembered for his work in gastrointestinal surgery, and for his investigations involving the thyroid gland. On ... Surgery of the thyroid and parathyroid glands by Daniel Oertli Works by or about Anton Wölfler at Internet Archive v t e ( ...
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The veins of the thyroid gland. The fascia and middle thyroid veins. Side view of the larynx, showing muscular attachments. ... The distance between the vocal processes and the angle of the thyroid is increased, and the folds are consequently elongated, ... Its action tilts the thyroid forward to help tense the vocal cords. The cricothyroid muscle originates from the anterolateral ... Cricothyroid ligament Larynx vocal fold Thyroid cartilage Vocology - science and practice of voice habilitation Adam's apple ...
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It works by decreasing the amount of thyroid hormone produced by the thyroid gland and blocking the conversion of thyroxine (T4 ... Groot, Leslie J. De; Jameson, J. Larry (2010). Endocrinology Adult and Pediatric: The Thyroid Gland. Elsevier Health Sciences. ... and actively concentrated to the thyroid gland. Depending on several patient variables, however, euthyroid status may not be ... report of a meeting jointly sponsored by the American Thyroid Association and the Food and Drug Administration". Thyroid. 19 (7 ...
In researching her thesis, Über die Thyreoidea von Kretinen und Idioten (On the Thyroid Glands of Cretins and Idiots), she ... 22 March 2011). "Inmunohistochemical Profile of Solid Cell Nest of Thyroid Gland". Endocrine Pathology. Springer. 22 (1): 35-39 ... long been of interest to pathologists as it is thought they could be behind ectopic structures in thyroid glands or in thyroid ... Bychkov, Andrey (September 2015). "Thyroid gland, Congenital anomalies, Solid cell nests". PathologyOutline.com. Retrieved 7 ...
... they are not malignant and they will not spread beyond the thyroid gland. Colloid nodules are the most common kind of thyroid ... Diana S. Dean, M.D. Hossein Gharib, M.D. (10 October 2010). "Fine-Needle Aspiration Biopsy of the Thyroid Gland, Chapter 6d". ... Ultrasound images of diseases of thyroid gland (CS1 maint: multiple names: authors list, All articles with unsourced statements ... "Ultrasound images of diseases of thyroid gland". medicalonly.com. Archived from the original on 23 September 2011. Retrieved 26 ...
Beebe, S. (1914). The Nerve Control of the Thyroid Gland. Beebe, S. P. (1915). The serum treatment of hyperthyroidism. Journal ... Beebe, S. P. (1918). Thyroid disease and the war. Med. Rec. (93); 237-238. Beebe, S. P. (1921). Iodine in the treatment of ... 1909). "A contribution to the physiology and chemistry of the parathyroid gland." The Journal of medical research. 20(2): 149. ... Beebe, S. P. (1911). Present Knowledge of Thyroid Function. Journal of the American Medical Association. 56(9): 658-660. Van ...
"Diagnosing Hyperthyroidism: Overactivity of the Thyroid Gland". endocrineweb. Savage, M W; P Mah; A Weetman; J Newell-Price (1 ... For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid ... goitre Hypothyroidism Thyroiditis Hashimoto's thyroiditis Thyroid cancer Thyroid hormone resistance Parathyroid gland disorders ... Endocrine gland hyperfunction/hypersecretion (leading to hormone excess) Tumours (benign or malignant) of endocrine glands ...
Ignjatovic, Mile (2003). "Historical review of the thyroid gland surgery". Acta Chirurgica Iugoslavica. 50 (3): 9-36. doi: ...
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The pituitary gland also controls the thyroid gland. The cranial cavity has a variety of spinal and cranial nerves residing in ... A gland that is found in this cavity is called the pituitary gland which secretes different fluids that are necessary for ... The body's temperature, physical, and sexual functions are regulated by this gland. One of the major glands are controlled ... The pituitary gland is also found in the make up of the cranial cavity. It plays a major role in the body, creating and ...
... is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the ... Its primary function is to increase the production of T3 and T4 by the thyroid gland. The most useful marker of thyroid gland ... or surgical removal of the thyroid gland. Thyroid surgery may also be performed to remove a thyroid nodule or to reduce the ... The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer". Thyroid. 26 (1): ...
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... and inflammation of endocrine organs that caused inflammation of the pituitary gland, of the thyroid (causing both ... insulin therapy or thyroid hormones). People have also had colon inflammation, liver inflammation, kidney inflammation due to ...
Hormones of the hypothalamus-pituitary-thyroid axis, Hormones of the thyroid gland, Iodinated tyrosine derivatives, Merck ... Levothyroxine is a synthetic form of thyroxine (T4), an endogenous hormone secreted by the thyroid gland, which is converted to ... Repeat thyroid function tests should be done five weeks after the dosage is increased. While a minimal amount of thyroid ... Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress TSH ...
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Cavalieri RR (April 1997). "Iodine metabolism and thyroid physiology: current concepts". Thyroid. 7 (2): 177-181. doi:10.1089/ ... In humans, zinc is primarily found in various organs and tissues such as the brain, intestines, pancreas and mammary glands. In ... Other biomolecules also contain metal ions in their structure, such as iodine in human thyroid hormones. Each biometal in your ...
As with other radioisotopes of iodine, accidental iodine-125 uptake in the body (mostly by the thyroid gland) can be blocked by ... Iodine-125 can be used in scanning/imaging the thyroid, but iodine-123 is preferred for this purpose, due to better radiation ... For radiotherapy ablation of tissues that absorb iodine (such as the thyroid), or that absorb an iodine-containing ... self-medicated preventive administration of stable KI is not recommended in order to avoid to disturb the normal thyroid ...
During embryonic development, the thyroid gland is being formed, beginning at the base of the tongue and moving towards the ... These tumors are generally papillary thyroid carcinomas, arising from the ectopic thyroid tissue within the cyst. Thyroglossal ... Thyroid scans and thyroid function studies are ordered preoperatively; this is important to demonstrate that normally ... Thyroglossal cysts are associated with an increased incidence of ectopic thyroid tissue. Occasionally, a lingual thyroid can be ...
... and C-cell adenomas/adenocarcinomas of the thyroid gland and tumors of the haemopoietic system in males. Second, Lewis rats are ... The most common are adenomas of the pituitary and adenomas/adenocarcinomas of the adrenal cortex in both sexes, mammary gland ... adrenal glands, and hearts are smaller. Scientists have bred many strains or "lines" of rats specifically for experimentation. ...
... thyroid, breast, lung, salivary glands, eye, and skin. MALT is populated by lymphocytes such as T cells and B cells, as well as ...
Thyroid and pancreas cancer may also occur. Although J Aidan Carney also described Carney's triad it is entirely different. ... The most common endocrine gland manifestation is an ACTH-independent Cushing's syndrome due to primary pigmented nodular ... Bano G, Hodgson S (2016). "Diagnosis and Management of Hereditary Thyroid Cancer". Recent Results Cancer Res. Recent Results in ...
Damage to peripheral nerves may impair sensation, movement, gland, or organ function depending on which nerves are affected; in ... Wood-allum, Clare A.; Shaw, Pamela J. (2014). "Thyroid disease and the nervous system". Neurologic Aspects of Systemic Disease ... Laboratory tests include blood tests for vitamin B-12 levels, a complete blood count, measurement of thyroid stimulating ... depending on the affected glands and organs, but common symptoms are poor bladder control, abnormal blood pressure or heart ...
... of the adrenal gland in hopes of avoiding life-long steroid replacement if the left and right adrenal glands need to be removed ... As MIBG therapy can destroy the thyroid, protective medications (potassium iodide) are started prior to treatment and need to ... the adrenal glands naturally produce more steroids; however, if the glands have been removed, they are unable to do so. ... When a tumor composed of the same cells as a pheochromocytoma develops outside the adrenal gland, it is referred to as a ...
Secreted thyroglobulin colloid and colloid nodules of the Thyroid gland Secreted casein 'micelles' of the mammary gland Serum ... Department of Agriculture developed a colloidal phase separation model for milk casein micelles that form within mammary gland ...
... and under/over-productive thyroid glands are the main causes of skin conditions. An Airedale's coat was originally designed to ...
... salivary glands, trachea, brain, prostate, spinal cord, and thyroid. Additionally, RNA-seq data illustrates transcript ... It has 4 transmembrane domains and is expressed in the lungs, thyroid, pancreas, intestines, spinal cord, and brain. Though its ...
The tumor, being in the pituitary gland, can cause secondary health problems. The immune system, thyroid levels, growth hormone ... A craniopharyngioma is a rare type of brain tumor derived from pituitary gland embryonic tissue that occurs most commonly in ... which can affect the function of the pituitary gland and many other hormones Reduction in prolactin production is very uncommon ...
... thyroid, kidneys, and adipose tissues. There is moderate expression in the brain, pancreas, mammary glands, and ovaries. ...
As studies of biological samples (including bone, thyroid glands and other tissues) have been undertaken, it has become ... and thyroid tissues as the most radiosensitive among women. For example, the FGR 13 has estimated that the ratio of thyroid ... Estimated Exposures and Thyroid Doses Received by the American People from Iodine-131 in Fallout Following Nevada Atmospheric ... The Hanford Thyroid Disease Study, an epidemiologic study of the relationship between estimated exposure doses to radioiodine ...
PFASs have been shown to decrease thyroid peroxidase, resulting in decreased production and activation of thyroid hormones in ... decreased mammary gland development, low birth weight (-0.7oz per 1 ng/mL increase in blood PFOA or PFOS level), decreased bone ... Song M, Kim YJ, Park YK, Ryu JC (August 2012). "Changes in thyroid peroxidase activity in response to various chemicals". ... "Probable Link Evaluation of Thyroid disease" (PDF). C8 Science Panel. July 30, 2012. "Probable Link Evaluation of Cancer" (PDF ...
... as well as the structure and function of the thyroid gland. Epitalon appears to increase the proliferation of lymphocytes in ... morphology and functions of the thyroid gland in neonatally hypophysectomized chicken and one-year-old birds". Patol Fiziol ... Epitalon and epithalamin appear to restore melatonin secretion by the pineal gland in both aged monkeys and humans. A human ... Khavinson, VKh; Morozov, VG (2003). "Peptides of pineal gland and thymus prolong human life". Neuro Endocrinol Lett. 24 (3): ...
There were also effects on the lungs, liver, kidney, and thyroid glands of male and female rats. The LD50, or 50% lethal dose ... Exposure to DCPA has shown damaging effects in the adrenal glands, kidneys, livers, thyroids, and spleens of laboratory animals ... in 1993 showed DCPA leading to thyroid tumors in male and female rats, and liver tumors in female rats. Alternatively, a 1963 ...
In the anterior pituitary gland, the effects of somatostatin are: Inhibiting the release of growth hormone (GH) (thus opposing ... the effects of growth hormone-releasing hormone (GHRH)) Inhibiting the release of thyroid-stimulating hormone (TSH) Inhibiting ... Somatostatin is then carried to the anterior pituitary gland, where it inhibits the secretion of growth hormone from ...
The release of this fluid is a product of the Skene's gland (female prostate), located within the walls of the urethra. The ... Males have a more pronounced Adam's apple or thyroid cartilage and deeper voices due to larger vocal cords. Males have larger ...
Patients with uncontrolled adrenal or thyroid dysfunction. Patient with known allergy to enclomiphene or clomiphene. Studies ... in the pituitary gland, which reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, thereby ... antagonizing the estrogen receptors in the pituitary gland, disrupting the negative feedback loop by estrogen towards the ...
Radiation therapy for cancers of the head and neck (including brachytherapy for thyroid cancers) where the salivary glands are ... A stimulated saliva flow rate less than 0.5 ml per gland in 5 minutes or less than 1 ml per gland in 10 minutes is decreased. ... Salivary gland hypofunction has been defined as any objectively demonstrable reduction in whole and/or individual gland flow ... Ascending (suppurative) sialadenitis - an infection of the major salivary glands (usually the parotid gland) that may be ...
He is noted for his pioneering research into the function of the thyroid gland. He also studied the effects of sex hormones on ...
... and thyroid gland lumps; they found no instances of leukemia, and a single case of lymph cancer that originated before the ... Students were described as afflicted with several health issues, such as headaches, rashes, bronchitis, blood and thyroid ... blood and thyroid abnormalities, and in extreme cases, lymphoma and leukemia. Levels of chlorobenzene in groundwater were ...
Certain Foods that Will Hurt Your Thyroid Gland. 13th July 2010. The thyroid gland is an important gland that is located in the ... Thyroid Disorders affecting 4.2 crore Indians every year1 On World Thyroid Day, the Indian Thyroid Society alerts general ... Thyroid Replacement in Fibromyalgia and CFS. Generic Thyroid, Thyroxine and the Hypothalamic Pituita. 12th November 2010 ... Could you have an underactive thyroid slowing down your body? Your thyroid produces hormones that are ess... Read ,. Author: ...
The thyroid gland is a butterfly-shaped gland located inside the front of the lower neck. ... Thyroid gland removal is surgery to remove all or part of the thyroid gland. ... Thyroid gland removal is surgery to remove all or part of the thyroid gland. The thyroid gland is a butterfly-shaped gland ... Too much thyroid hormone (thyroid storm). If you have an overactive thyroid gland, you will be treated with medicine. ...
... here is information on life without a thyroid gland... ... Whether you dont have a thyroid gland due to congenital ... Thyroid. How Someone Ends Up Without a Thyroid. There are several ways that someone can end up without a thyroid gland. First, ... No Thyroid Gland Means You are Hypothyroid. Whether you dont have a thyroid gland because you were born that way, or have had ... People without a thyroid gland may find that they need the addition of the T3 hormone in some form. A functional thyroid gland ...
Metka Logonder-Mlinšek, Miroslav Kališnik & Zdenka Pajer, «Follicular, parafollicular and mast cells in mouse thyroid gland ... Follicular, parafollicular and mast cells in mouse thyroid gland after antithyroid drug application (Volume 4 (1985) - Number 1 ... Follicular, parafollicular and mast cells in mouse thyroid gland after antithyroid drug application ...
We have received an influx of inquiries from a company called Gold Life Choice (formally Life Choice Keto) regarding subscription cancellations and charges. We are not associated with this company, we are a Canadian company, Life Choice Ltd. Please reach out to this company at 1-833-794-0942.. ...
The hormones secreted by the thyroid gland contain triiodo-thyronine (T3), tetraiodothyronine (T4; generally termed thyroxine) ... The thyroid gland weighs about 25 grams. Every lobe of the thyroid gland is 5 cm long, 3 cm wide and 2 cm thick (5 X 3 X 2 cm ... Ectopic thyroid: The Thyroid gland (thyroid tissue) may be seen at an abnormal position anywhere along the course of ... Effects of Huge Enlargement of Thyroid Gland. The thyroid gland can enlarge backwards or downwards but it can not enlarge ...
Tag Archives: thyroid gland. Give Me Strength and Stream of Consciousness. Posted on August 16, 2013. by noellesvoice ... thyroid gland, Universe , 2 Replies Follow Blog via Email. Enter your email address to follow this blog and receive ... It is an auto-immune disease where my body produces antibodies which then fight and try to destroy my thyroid gland. In case ... some dont know it, the thyroid sits in the front of the neck, towards the base. This is also an area called the throat chakra ...
Your thyroid gland plays a vital role in controlling your weight, maintaining your energy levels, keeping your immune system ... Thyroid Health. Thyroid Health - Your thyroid gland plays a vital role in controlling your weight, maintaining your energy ... The health of your liver, adrenal glands, immune system and reproductive system all affect the function of your thyroid gland. ... Your thyroid is one of the most important glands in your body. It controls the way you metabolize food, the way you use energy ...
It is thought to have an impact on the pituitary, thyroid, adrenals, and gonads, though no one is sure how or why. Our ability ... What you will have in this course : Initiation of one code that will help to purify the gland Initiation of 3 code which ... French philosopher Rene Descartes believed that the pineal gland was the home of the SOUL in the seventh century. Recent ... Codes Initiations of all these Code which will help you to just voice out these words and let the magik happen in your gland. ...
For describing the thyroids functions, the Swiss surgeon Theodor ... The thyroid gland was first identified in 1656 by the English ... The thyroid gland was first identified in 1656 by the English anatomist Thomas Wharton. For describing the thyroids functions ... Starting in 1874, Kocher removed the entire thyroid gland from a series of patients with enlarged glands over the next decade. ... The thyroid is among the largest of the endocrine glands, present in all vertebrates, and located in the neck region in ...
... functions of thyroid glands, gland 7, healthy thyroid gland, importance of thyroid gland, levels of thyroid, levels of thyroid ... thyroid disease, thyroid gland, thyroid gland hormones and functions, thyroid weight gain, thyroxine function, weight gain, ... function of thyroid, function of thyroid gland, functions of thyroid, functions of thyroid gland, ... what is the function of thyroid gland in human body, what is the main function of thyroid gland Leave a comment ...
4.1 Thyroid gland 4.2 Parathyroid glands 4.3 Salivary glands 4.4 Lymph nodes 4.5 Miscellaneous Breast and Axilla ... 1.10 Adrenal glands 1.11 Abdominal wall 1.12 Miscellaneous Urinary Tract and male reproductive system ...
FNA performed to confirm this is thyroid tissue. On US there is no connection to the thyroid gland which lies in level 6 and is ... This tends to be hypoechoic and tends to be inferior to the thyroid lobe. This can also be found within the thyroid gland. It ... 19.6 Thyroid Nodules. 19.7 US Characteristics of Thyroid Nodules: What to Look for and What to Include in Our US Thyroid Report ... 19.1 Size of the Thyroid Gland. Size of the thyroid is normally measured in volume with measurement taken in three dimensions. ...
... The thyroid is a radiation-sensitive organ of the human body and therefore in ... Home / Product Catalog / X-ray protection / X-ray protective clothing / RA614 Thyroid Gland and Sternum Protection Mavig ... Our thyroid and sternum protector is characterised by its first-class cut and the best fit, taking into account all aspects of ... With a permanently sewn-on hook & burr closure in the neck as standard, the thyroid and sternum protection is optionally also ...
Thyroid gland anomalies. The thyroid gland forms as a diverticulum from the floor of the pharynx (tuberculum impar) at a site ... Confirmation of a normally functioning thyroid gland is important; therefore, always palpate the thyroid gland during the ... The thyroid gland then forms 2 lobes and descends along a hollow canal called the thyroglossal duct in the midline of the neck ... Arrest in the normal descent of the gland results in ectopic thyroid tissue. ...
The discovery of a tumor as a primary schwannoma in the thyroid gland is rare (Andrion et al. in Virchows Arch 413367-372, 1988 ... Unexpected Tumor: Primary Asymptomatic Schwannoma in Thyroid Gland. Vázquez-Benítez, G; Pérez-Campos, A; Masgrau, N Alberti; ... It constitutes a highly useful tool for diagnosing non-epithelial neoplasia of the thyroid gland. ... Unexpected Tumor: Primary Asymptomatic Schwannoma in Thyroid Gland. ...
WHAT IS THE THYROID GLAND?. The thyroid gland is a butterfly-shaped endocrine gland that is normally located in the lower front ... Thyroid Eye Disease. Thyroid Function Tests. Thyroid Hormone Treatment. Thyroid Nodules. Thyroid Surgery. Thyroid & Weight. ... Hypothyroidism is an underactive thyroid gland. Hypothyroidism means that the thyroid gland cant make enough thyroid hormone ... Surgical removal of part or all of the thyroid gland. Some people with thyroid nodules, thyroid cancer, or Graves disease need ...
Werners the thyroid : a fundamental and clinical text / edited by Sidney H. Ingbar, Lewis E. Braverman. by Werner, Sidney ... by International Thyroid Congress (9th: 1985: São Paulo, Brazil) , Medeiros-Neto, Geraldo A , Gaitan, Eduardo. ... Frontiers in thyroidology : proceedings of the Ninth International Thyroid Congress, held September 1-6, 1985, in São Paulo, ...
We report a case of 22-years-old woman with right leg rhabdomyosarcoma metastatic to the thyroid gland. ... Soft tissue sarcomas metastatic to the thyroid are extremely rare as the majority of thyroid metastasis are caused by tumors of ... Nevertheless, thyroid metastases are not an exceptional finding at autopsy, they are encountered in 2 % to 24 % of the patients ... The thyroid gland is a known but an unusual site for metastatic tumors from various primary sites. Despite the fact that it is ...
Dive into the research topics of The Parathyroid Glands in Thyroid Surgery. Together they form a unique fingerprint. ...
Reminder, dont confuse the Adams apple with the thyroid gland. The thyroid gland is located further down on your neck, closer ... When discussing health and wellness, the thyroid gland isnt likely a hot topic between friends and family. This tiny gland is ... Common thyroid conditions and symptoms:. When your thyroid doesnt produce enough thyroid hormone, your system slows down. When ... including all those related to the thyroid gland. Remember, although thyroid disease is often a life-long condition, it can be ...
The thyroid gland covers the windpipe from three sides. Two ho ... Function Of The Thyroid Gland Image. Thyroid gland. Medically ... Thyroid gland. Medically reviewed by Healthlines Medical Network on February 18, 2015. ... Tags: function, gland, thyroid. This entry was posted in Diagrams and tagged function, gland, thyroid by admin. Bookmark the ... The thyroid gland covers the windpipe from three sides. Two hormones of the thyroid gland, T4 (thyroxine) and T3 ( ...
The impact on thyroid gland function remains unknown.. AB - We aimed to evaluate changes in thyroid gland size during the ... title = "Effect of chemoradiation on the size of the thyroid gland",. abstract = "We aimed to evaluate changes in thyroid gland ... Effect of chemoradiation on the size of the thyroid gland. Ana Marcella Rivas, Eneko Larumbe-Zabala, Olaia Diaz-Trastoy, Ryan ... Effect of chemoradiation on the size of the thyroid gland. / Rivas, Ana Marcella; Larumbe-Zabala, Eneko; Diaz-Trastoy, Olaia et ...
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... ... AIM: To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated thyroid cancer. METHODS: A ...
overactive thyroid gland * a condition with low thyroid hormone levels * increased eosinophils in the blood ...
3 - Thyroid gland insufficiency or hyperactivity. The thyroid gland is important for your metabolism. It produces the T3 and T4 ... Men can also suffer from testosterone insufficiency or problems from the thyroid gland. It can bring brain fog suddenly to ... That is why engaging in a mild exercise could significantly improve your health, make your thyroid gland work better, and give ... In case you have a thyroid gland insufficiency your hormones can also get affected. ...
Primary squamous cell carcinoma of the thyroid gland: A case report and role of radiotherapy.. Lookup NU author(s): Richard ...
  • Although not always the case, the patient with an ectopic thyroid often is hypothyroid and consequently has elevated thyroid-stimulating hormone (TSH). (medscape.com)
  • however, an ectopic thyroid gland cannot be ruled out even in the presence of reference range TSH levels and a clinically euthyroid history. (medscape.com)
  • Aberrant/ectopic thyroid: Incidental findings of a lesion in right level 3 in a 60-year-old patient. (pocketdentistry.com)
  • A few have part or all of their thyroid in the wrong place (ectopic thyroid). (thyroid.org)
  • A wide range of morphological and developmental variations of thyroid gland like hypoplasia, ectopic thyroid tissue, hemiagenesis or agenesis of thyroid gland has been reported. (who.int)
  • If you're worn-out most of the time, your physician is probably going to request blood tests on the two thyroid hormones referred to as T3 thyroid and thyroxinine and even the brain hormones called TSH and prolactin. (articlealley.com)
  • Your thyroid produces hormones that are ess. (articlealley.com)
  • The thyroid gland is an important gland that is located in the neck area and it makes certain hormones that are important to your body and the way that it functions. (articlealley.com)
  • It's the only endocrine gland that depends on external environment for raw material, iodine, to synthesize its hormones. (earthslab.com)
  • It's the only endocrine gland, which doesn't pour its hormones into blood immediately after formation but stores them and after that discharges them in blood to be used as and when needed. (earthslab.com)
  • Thyroid hormones play a major role in the development of vertebrates. (healthsignal.net)
  • The thyroid's job is to make thyroid hormones, which are secreted into the blood and then carried to every tissue in the body. (thyroid.org)
  • Two hormones of the thyroid gland, T4 (thyroxine) and T3 (triiodothyronine), help the body to produce and regulate the hormones adrenaline (also called epinephrine) and dopamine. (anatomysystem.com)
  • Another gland, called the pituitary gland, tells your thyroid how much of these hormones your body needs. (anatomysystem.com)
  • Thyroid hormones and cytogenetic outcomes in backpack sprayers using ethylenebis(dithiocarbamate) (EBDC) fungicides in Mexico. (cdc.gov)
  • In the United States, surgery to remove the thyroid gland, called a thyroidectomy , is most commonly performed on many patients who have been diagnosed with thyroid cancer , or who have had inconclusive thyroid nodule biopsies that couldn't rule out thyroid cancer. (holtorfmed.com)
  • Thus, to avert hemorrhage during thyroidectomy, the thyroid gland is removed together with the true capsule. (earthslab.com)
  • The thyroidectomy specimen showed diffuse infiltration of the thyroid tissue by similar tumour (Figure 2 A & 2 B), which showed also identical immunorecativty to the original specimen. (biomedcentral.com)
  • The blood samples were analyzed for serum thyroxine (T4) and thyroid stimulating hormone (TSH). (cdc.gov)
  • Twenty (20) patients with breast cancer received SC RT, with evaluation [email protected] of thyroid functions in both groups, including thyroid stimulating hormone and free thyroxine prior to RT and 3, 6, 9, 12, 18 and 24 months after RT. (who.int)
  • You may also have surgery if you have an overactive thyroid gland and do not want to have radioactive iodine treatment, or you cannot be treated with antithyroid medicines. (medlineplus.gov)
  • You may also need thyroid medicine or iodine treatments 1 to 2 weeks before your surgery. (medlineplus.gov)
  • Like every cell and organ in our bodies, the thyroid requires specific vitamins and minerals to carry out everyday functions eg Iodine and Selenium. (holistichealthandbeautyshop.com)
  • Some people with Graves' disease, nodular goiter, or thyroid cancer are treated with radioactive iodine (I-131) for the purpose of destroying their thyroid gland. (thyroid.org)
  • HTDS) is a scientific study conducted the 1940s in southeastern Washington iodine-131, researchers investigated to determine whether the risk of State to produce plutonium for nuclear a group of people with a wide range thyroid disease is increased among weapons. (cdc.gov)
  • Did exposure to iodine-131 information showed that large suggest that young children may be result in increased incidence of amounts of iodine-131 and other the most susceptible to the effects thyroid disease? (cdc.gov)
  • Data Col ection -- Participants underwent conducted the scientific and technical iodine-131 through complete evaluations for thyroid disease, work. (cdc.gov)
  • Whether you don't have a thyroid gland because you were born that way, or have had your thyroid surgically removed, the end result is that you are hypothyroid. (holtorfmed.com)
  • You can be hypothyroid and still have a thyroid gland - your gland, however, is not producing enough of the essential thyroid hormone, which delivers oxygen and energy to the cells, tissues, and organs of the body. (holtorfmed.com)
  • Hypothyroid and Thyroidless vs Hypothyroid with a Thyroid: What's the Difference? (holtorfmed.com)
  • What are the key differences for patients who are hypothyroid due to lack of a gland, versus those who still have a thyroid gland, but whose gland is not producing any or enough hormone? (holtorfmed.com)
  • The effect of thyroid hormone on growth is mostly seen in growing children, with hypothyroid children exhibiting mental retardation and growth that is slow and stunted. (healthsignal.net)
  • People are hypothyroid if they have too little thyroid hormone in the blood. (thyroid.org)
  • If the whole thyroid is removed, people will definitely become hypothyroid. (thyroid.org)
  • It's the only endocrine gland that is situated superficially in the body, for this reason reachable for physical examination. (earthslab.com)
  • The thyroid gland which occurs in the base region of our neck is a very important endocrine gland which regulates hormone secretion for a healthy body. (possible.in)
  • Some people deal with hypothyroidism, which occurs when the thyroid is underactive. (articlealley.com)
  • Hypothyroidism is a term that refers to a condition where you have insufficient thyroid hormone. (holtorfmed.com)
  • Whether a patient has a thyroid or not, hypothyroidism requires thyroid hormone replacement treatment. (holtorfmed.com)
  • When a gland is still present, it may still be providing some thyroid hormone, but the thyroid's hormone production may fluctuate, shifting a patient from mild hyperthyroidism to mild hypothyroidism, and causing fluctuating blood test levels and changes to more frequent changes to medication dosage. (holtorfmed.com)
  • Since you have no T3 being produced by your thyroid, if you are taking a T4-only drug like levothyroxine, if your T4 to T3 conversion is not optimal, you may find yourself low in active thyroid hormone, which can cause hypothyroidism symptoms unless a T3 drug (like liothyronine, or natural desiccated thyroid) is added to your treatment. (holtorfmed.com)
  • Hypothyroidism is an underactive thyroid gland. (thyroid.org)
  • Hypothyroidism means that the thyroid gland can't make enough thyroid hormone to keep the body running normally. (thyroid.org)
  • Because thyroid disease runs in families, you should explain your hypothyroidism to your relatives and encourage them to get periodic TSH tests. (thyroid.org)
  • Several disorders can arise if the thyroid produces too much hormone (hyperthyroidism) or not enough (hypothyroidism). (kalonwomen.com)
  • The thyroid gland is a butterfly-shaped gland located inside the front of the lower neck. (medlineplus.gov)
  • Small yet mighty, the thyroid is a butterfly-shaped gland located in the base of the neck. (kalonwomen.com)
  • If you have an overactive thyroid gland, you will be treated with medicine. (medlineplus.gov)
  • Graves' disease is caused by the immune system mistakenly attacking the thyroid, which causes it to become overactive. (kalonwomen.com)
  • Could you have an underactive thyroid slowing down your body? (articlealley.com)
  • It represents less than 1 % of mesenchymal neoplasms of this gland. (bvsalud.org)
  • For this reason, ultrasonography, CT scanning, thyroid scanning, or magnetic resonance imaging (MRI) may be warranted to document a normal thyroid gland. (medscape.com)
  • The echotexture of the normal thyroid gland parenchyma is homogeneous throughout, higher in echogenicity than the overlying strap muscles. (pocketdentistry.com)
  • Neck ultra sound revealed an enlarged right thyroid lobe with hypoechoic heterogenous nodule measuring 4 x 2 cm with other 2 small hypoechoic nodules in the same lobe. (biomedcentral.com)
  • FNAC from the thyroid nodule proved to be undifferentiated malignant tumor. (biomedcentral.com)
  • In some cases, surgery is also performed as a treatment for an enlarged thyroid, known as a goiter, or multiple nodules. (holtorfmed.com)
  • Size is important when there are nodules or if the thyroid is seen to be pathological. (pocketdentistry.com)
  • Some people with thyroid nodules , thyroid cancer , or Graves' disease need to have part or all of their thyroid removed. (thyroid.org)
  • Graves disease is an autoimmune disorder of the thyroid caused by stimulatory thyroid-stimulating hormone receptor antibodies, leading to hyperthyroidism. (medscape.com)
  • Common causes are autoimmune disease, such as Hashimoto's thyroiditis , surgical removal of the thyroid, and radiation treatment. (thyroid.org)
  • There are also thyroid diseases with long-term impact, such as Hashimoto's thyroiditis, Graves' disease and thyroid eye disease. (kalonwomen.com)
  • Also called Hashimoto's disease, is the most common thyroid disease in the United States. (kalonwomen.com)
  • Hashimoto's disease involves the production of immune cells and autoantibodies by the body's immune system that can damage thyroid cells and compromise their ability to make thyroid hormone. (kalonwomen.com)
  • The thyroid gland is a known but an unusual site for metastatic tumors from various primary sites. (biomedcentral.com)
  • Soft tissue sarcomas metastatic to the thyroid are extremely rare as the majority of thyroid metastasis are caused by tumors of the kidneys, lungs, mammary glands, ovaries , and colon or by melanomas. (biomedcentral.com)
  • Every lateral lobe of the gland goes upwards to the oblique line of the thyroid cartilage and below up to the 5th or 6th tracheal ring. (earthslab.com)
  • Every lobe of the thyroid gland is 5 cm long, 3 cm wide and 2 cm thick (5 X 3 X 2 cm). (earthslab.com)
  • On the medial surface of thyroid lobe it thickens to create the suspensory ligament ofBerry, which attaches the lobe to the cricoid cartilage. (earthslab.com)
  • This would enable to scan the thyroid lobe in its maximum dimension. (pocketdentistry.com)
  • IMSEAR at SEARO: Agenesis of Isthmus of thyroid gland with presence of pyramidal lobe and levator glandulae thyroideae. (who.int)
  • When thyroid hormone levels are too low, the body's cells can't get enough thyroid hormone and the body's processes start slowing down. (thyroid.org)
  • There can be many reasons why the cells in the thyroid gland can't make enough thyroid hormone. (thyroid.org)
  • Then there aren't enough thyroid cells and enzymes left to make enough thyroid hormone. (thyroid.org)
  • If part of the gland is left, it may be able to make enough thyroid hormone to keep blood levels normal. (thyroid.org)
  • When your thyroid doesn't produce enough thyroid hormone, your system slows down. (kalonwomen.com)
  • radioactive materials were released of radiation on the thyroid gland. (cdc.gov)
  • Surgery to remove your whole thyroid may take 2 to 3 hours. (medlineplus.gov)
  • This is done more often when the whole thyroid gland is removed. (medlineplus.gov)
  • Injury to the parathyroid glands (small glands near the thyroid) or to their blood supply. (medlineplus.gov)
  • Posterior: Oesophagus tends to be on the left, rarely on the right, longus colli, parathyroid gland (only seen if this is enlarged). (pocketdentistry.com)
  • It is thought to have an impact on the pituitary, thyroid, adrenals, and gonads, though no one is sure how or why. (innerwonderlust.com)
  • Out of these agenesis of the thyroid isthmus is a very rare congenital anomaly. (who.int)
  • COVID-19-related autoimmune thyroid manifestations include Graves disease and thyroid eye disease (TED), although COVID-19 can lead to multiple other thyroid dysfunctions. (medscape.com)
  • ACE-2 is highly expressed in thyroid cells, and COVID-19 has been reported to cause thyroid dysfunction both during and after infection with SARS-CoV-2. (medscape.com)
  • Hence thyroid swellings can be differentiated medically from other swellings in the region of the neck. (earthslab.com)
  • Occasionally the thyroid tumor goes backwards, as the capsule is thin along the posterior edges of the lateral lobes, compressing the adjacent structures without creating a visible swelling on the very front of the neck. (earthslab.com)
  • In case some don't know it, the thyroid sits in the front of the neck, towards the base. (wordpress.com)
  • Hyperechoic tissue found lateral to the carotid artery, it has the same echogenicity as the right thyroid. (pocketdentistry.com)
  • When it's found, newborns are started on thyroid hormone replacement, to avoid the signs and symptoms of this condition, which can include failure to grow, lethargy, developmental delays, and even mental impairment. (holtorfmed.com)
  • Your symptoms should disappear and the serious effects of low thyroid hormone should improve. (thyroid.org)
  • However, thyroid disease affects as many as 30 million Americans, and more than half remain undiagnosed because symptoms are often similar to the signs of other medical conditions. (kalonwomen.com)
  • Thyroid isthmus agenesis does not manifest clinical symptoms, and it can be confused with other thyroid pathologies. (who.int)
  • Primary squamous cell carcinoma of the thyroid gland: A case report and role of radiotherapy. (ncl.ac.uk)
  • Note: warnings about soy still apply, however, as soy can interfere with the body's ability to absorb thyroid hormone. (holtorfmed.com)
  • Ensuring the thyroid gland is healthy and functioning properly is vitally important to the body's overall well-being," said Dr. Felice Caldarella, president of the American Association of Clinical Endocrinology . (kalonwomen.com)
  • Surgical removal of part or all of the thyroid gland. (thyroid.org)
  • We report a case of 22-years-old woman with right leg rhabdomyosarcoma metastatic to the thyroid gland. (biomedcentral.com)
  • If the gland is not palpated, ultrasonography or computed tomography (CT) scanning may be valuable. (medscape.com)
  • There may also be a lateral aberrant thyroid tissue in the neck. (pocketdentistry.com)
  • The sarcoma tissue invades between the thyroid follicles (H&E x100) (A). The tumour cells show significant pleomorphism (H&E x200), (B), diffuse immunoreactivity to vimentin (DAB peroxidase x100) (C) and desmin (DAB peroxidase x200) (D). (biomedcentral.com)
  • No single organ in your body functions independently of the others, and this is very much the case with the thyroid gland. (holistichealthandbeautyshop.com)
  • The thyroid is a radiation-sensitive organ of the human body and therefore in particular need of protection. (oncomedica.ua)
  • Thus, 1690, that an organ such as the thyroid secretin was the first hormone to be isolat- pours into the blood substances of physio- ed. (who.int)
  • Thyroid Disorders affecting 4.2 crore Indians every year1 On World Thyroid Day, the Indian Thyroid Society alerts general public and doctors on the highly prevalent and undiagnosed disease Lucknow, May 19, 2011: Ahead of World Thyroid Day, the message f. (articlealley.com)
  • A lighter application of mascara will reduce this problem as well as avoiding rubbing of the eyes while the mascara is worn.Thyroid Conditions Thyroid disorders can effect general hair growth. (articlealley.com)
  • Up to half of the people who have Graves' disease may develop thyroid eye disease over time. (kalonwomen.com)
  • TED is the most common complication of Graves disease that occurs outside of the thyroid gland. (medscape.com)
  • ABSTRACT The first description of thyroid diseases as they are known today was that of Graves disease by Caleb Parry in 1786, but the pathogenesis of thyroid disease was not discovered until 1882-86. (who.int)
  • RÉSUMÉ La première description des pathologies thyroïdiennes, telles qu'on les connaît aujourd'hui, a été celle de la maladie de Graves par Caleb Parry en 1786, mais la pathogenèse de l'affection thyroïdienne n'a pas été découverte avant 1882-1886. (who.int)
  • Function Of The Thyroid Gland Image diagram and chart - Human body anatomy diagrams and charts with labels. (anatomysystem.com)
  • While they were studying the effects historical developments in our knowledge of "pancreatic juices" on the duodenal mu- of anatomy and physiology of the thyroid cosa, they isolated a substance, giving it gland. (who.int)
  • Nevertheless, thyroid metastases are not an exceptional finding at autopsy, they are encountered in 2 % to 24 % of the patients with malignant neoplasm. (biomedcentral.com)
  • Thyroid gland removal is surgery to remove all or part of the thyroid gland. (medlineplus.gov)
  • A sharp rise in thyroid hormone levels (only around the time of surgery). (medlineplus.gov)
  • A functional thyroid gland produces both T4 - the inactive thyroid hormone, and some T3. (holtorfmed.com)
  • It is an auto-immune disease where my body produces antibodies which then fight and try to destroy my thyroid gland. (wordpress.com)
  • Werner's the thyroid : a fundamental and clinical text / edited by Sidney H. Ingbar, Lewis E. Braverman. (who.int)
  • Brown-Séquard the clinical features of thyroid disease since demonstrated that in animals death from the dawn of the 20th century, the methods adrenalectomy could be delayed by infu- of investigation and treatment advanced sion of blood from healthy animals. (who.int)
  • This paper reviews the main landmarks in the history of thyroid disease, supplemented by a brief discussion of the historically relevant scientific aspects of the thyroid gland, and the evolution of endocrinology as a formal discipline. (who.int)
  • By in the history of thyroid disease, starting with a brief outline of the evolution of mod- the end of the 19th century a number of ern endocrinology. (who.int)
  • There are exceptions: many patients with viral thyroiditis have their thyroid function return to normal, as do some patients with thyroiditis after pregnancy. (thyroid.org)
  • Thyroiditis is an inflammation of the thyroid gland, usually caused by an autoimmune attack or by a viral infection. (thyroid.org)
  • Having a low function thyroid can cause eyelash hair loss. (articlealley.com)
  • The health of your liver, adrenal glands, immune system and reproductive system all affect the function of your thyroid gland. (holistichealthandbeautyshop.com)
  • All these patients can lose part or all of their thyroid function. (thyroid.org)
  • If the thyroid does not function correctly, it can affect every aspect of a person's life. (kalonwomen.com)
  • This entry was posted in Diagrams and tagged function , gland , thyroid by admin . (anatomysystem.com)
  • The impact on thyroid gland function remains unknown. (elsevierpure.com)
  • The authors conclude that heavy exposure to EBDC fungicides appears to affect thyroid function and the lymphocyte genome. (cdc.gov)
  • Perchlorate can disrupt the normal function of the thyroid gland in both children and adults. (cdc.gov)
  • Neck and chest computed tomography (CT) images were used to calculate thyroid gland volume before and after therapy, using Vitrea ® software or the volumetric ellipsoid method. (elsevierpure.com)
  • Also the presence of levator glandulae thyroideae and its anatomical variations gain importance in the pathologies which are related to thyroid gland and their treatment modalities. (who.int)
  • Results of search for 'su:{Thyroid gland. (who.int)
  • Thyroid Health - Your thyroid gland plays a vital role in controlling your weight, maintaining your energy levels, keeping your immune system strong and boosting your mood. (holistichealthandbeautyshop.com)
  • In some people's bodies, the immune system that protects the body from invading infections can mistake thyroid gland cells and their enzymes for invaders and can attack them. (thyroid.org)
  • Thyroid eye disease is an autoimmune disorder that causes your immune system to mistakenly attack the tissues behind your eyes. (kalonwomen.com)
  • To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated thyroid cancer. (bvsalud.org)
  • Most people need to take thyroid hormone pills (thyroid hormone replacement) for the rest of their lives when the whole gland is removed. (medlineplus.gov)
  • Our thyroid and sternum protector is characterised by its first-class cut and the best fit, taking into account all aspects of radiation protection. (oncomedica.ua)
  • While no study can determine the cause of an individual case of thyroid disease, an epidemiological study, such as the HTDS, provides the best way to determine whether disease has increased in a population exposed to a potentially harmful agent such as radiation. (cdc.gov)
  • of radiation doses to the thyroid. (cdc.gov)
  • thyroid radiation doses occurred. (cdc.gov)
  • We aimed to evaluate changes in thyroid gland size during the treatment of malignancies outside the head and neck with chemotherapy and/or external beam radiation. (elsevierpure.com)
  • Exposure to radiation or chemotherapy was not found to be associated with the degree of thyroid gland reduction, nor was the number of days between CT scans or the stage of the malignancy being treated. (elsevierpure.com)
  • Our results showed that the treatment of malignancies outside the head and neck with chemotherapy and/or external beam radiation results in a reduction in thyroid gland size. (elsevierpure.com)
  • therefore, always palpate the thyroid gland during the physical examination. (medscape.com)
  • Fred Hutchinson Cancer Research evaluation of thyroid disease. (cdc.gov)
  • elevated cancer incidence risk for kidney [SIR = 6.25 (1.26 18.3)] and thyroid [3.97 (1.45-8.65)] was also observed. (cdc.gov)
  • In conclusion, this study found a significantly increased risk of thyroid, prostate, colon, and bladder cancer among male firefighters. (cdc.gov)
  • Remember, although thyroid disease is often a life-long condition, it can be managed. (kalonwomen.com)
  • The guide summarizes the findings, explains how and why the study was conducted, and includes information about the treatment of thyroid disease. (cdc.gov)
  • many people who lived in areas contaminated food, the HTDS around Hanford where the highest focused on thyroid disease. (cdc.gov)
  • The thyroid is among the largest of the endocrine glands, present in all vertebrates, and located in the neck region in tetrapods (those with limbs having digits). (healthsignal.net)
  • The present case report is an attempt to highlight the implications of variation of thyroid gland from diagnostic, phylogenetic and functional perspectives. (who.int)
  • First, you can be born without a gland, or with a malformed or non-functional gland. (holtorfmed.com)
  • Delineated above, the pretracheal fascia after enclosing the thyroid gland is connected to the oblique lines of the thyroid cartilage and the body of the hyoid bone in the midline. (earthslab.com)
  • Normal appearance of the thyroid gland is of a butterfly in the midline of anterior neck. (pocketdentistry.com)
  • Finally, the degree of thyroid gland size reduction did not predict mortality. (elsevierpure.com)
  • Frontiers in thyroidology : proceedings of the Ninth International Thyroid Congress, held September 1-6, 1985, in São Paulo, Brazil / edited by Geraldo Medeiros-Neto and Eduardo Gaitan. (who.int)
  • Scientists also ensured concentrates in the thyroid gland decision by Congress to mandate that the HTDS participants included when it is inhaled or consumed in the HTDS in 1988. (cdc.gov)