A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Protein Disulfide Reductase (Glutathione)
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Heterocyclic Compounds, Bridged-Ring
Oxidoreductases Acting on Sulfur Group Donors
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
Receptors, Amino Acid
Cell surface proteins that bind amino acids and trigger changes which influence the behavior of cells. Glutamate receptors are the most common receptors for fast excitatory synaptic transmission in the vertebrate central nervous system, and GAMMA-AMINOBUTYRIC ACID and glycine receptors are the most common receptors for fast inhibition.
Amino Acid Sequence
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Chromatography, High Pressure Liquid
Cobra Neurotoxin Proteins
Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Protein Structure, Secondary
Carrier proteins for OXYTOCIN and VASOPRESSIN. They are polypeptides of about 10-kDa, synthesized in the HYPOTHALAMUS. Neurophysin I is associated with oxytocin and neurophysin II is associated with vasopressin in their respective precursors and during transportation down the axons to the neurohypophysis (PITUITARY GLAND, POSTERIOR).
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Protein Structure, Tertiary
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Analysis of PEPTIDES that are generated from the digestion or fragmentation of a protein or mixture of PROTEINS, by ELECTROPHORESIS; CHROMATOGRAPHY; or MASS SPECTROMETRY. The resulting peptide fingerprints are analyzed for a variety of purposes including the identification of the proteins in a sample, GENETIC POLYMORPHISMS, patterns of gene expression, and patterns diagnostic for diseases.
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
NADH, NADPH Oxidoreductases
A group of oxidoreductases that act on NADH or NADPH. In general, enzymes using NADH or NADPH to reduce a substrate are classified according to the reverse reaction, in which NAD+ or NADP+ is formally regarded as an acceptor. This subclass includes only those enzymes in which some other redox carrier is the acceptor. (Enzyme Nomenclature, 1992, p100) EC 1.6.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Electrophoresis, Polyacrylamide Gel
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
Amino Acid Substitution
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 126.96.36.199.
Carbon forms disulfides and diselenides. Silicon forms several hydrides; two of them are SiH4 and Si2H6. Silicon forms ... Silicon also forms a dioxide and a disulfide. Silicon nitride has the formula Si3N4. Germanium forms five hydrides. The first ... Germanium bonds to all natural single chalcogens except polonium, and forms dioxides, disulfides, and diselenides. Germanium ...
List of alchemical substances
Sb2O3 Fool's gold - a mineral, iron disulfide or pyrite; can form oil of vitriol on contact with water and air. Fulminating ... or ferrous sulfate) Marcasite - a mineral; iron disulfide. In moist air it turns into green vitriol, FeSO4. Rouge/Crocus/ ... Used for glass coloring Quicksilver - Mercury Realgar - arsenic disulfide, an ore of arsenic Red Vitriol - cobalt sulfate ...
metal dichalcogenides such as tantalum disulfide, titanium disulfide, and vanadium disulfide. graphite iron oxychloride layered ... Revelli, J. F.; Disalvo, F. J. (1995). "Tantalum Disulfide (TaS2) and Its Intercalation Compounds". Inorganic Syntheses. 30: ... Mckelvy, M. J.; Claunsinger, W. S. (1995). "Titanium Disulfide". Inorganic Syntheses. 30: 28-32. doi:10.1002/9780470132616.ch7 ...
Also called "white graphite." Tungsten disulfide. Similar usage as molybdenum disulfide, but due to the high cost only found in ... Molybdenum disulfide (MoS2). Used in CV joints and space vehicles. Does lubricate in vacuum. Hexagonal boron nitride. Used in ... Graphite and molybdenum disulfide are the predominant materials used as dry lubricants. The lubricity of many solids is ... The two main dry lubricants are graphite and molybdenum disulfide. They offer lubrication at temperatures higher than liquid ...
Disulfides reduce to thiols (via thiolates). LiBHEt3 deprotonates carboxylic acids, but does not reduce the resulting lithium ...
1,2-Dithiolanes are cyclic disulfides. Some dithiolanes are natural products that can be found in foods, such as asparagusic ...
Protein disulfide-isomerase, also known as the beta-subunit of prolyl 4-hydroxylase (P4HB), is an enzyme that in humans encoded ... Tian G, Xiang S, Noiva R, Lennarz WJ, Schindelin H (January 2006). "The crystal structure of yeast protein disulfide isomerase ... Ko HS, Uehara T, Nomura Y (September 2002). "Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic ... Bastos-Aristizabal S, Kozlov G, Gehring K (May 2014). "Structural insight into the dimerization of human protein disulfide ...
... is often used as a reducing agent to break disulfide bonds within and between proteins as a preparatory step for gel ... TCEP can keep the cysteines from forming di-sulfide bonds and unlike dithiothreitol and β-mercaptoethanol, it will not react as ... Ruegg, U.T & Rudinger, J. (1977). "Reductive cleavage of cystine disulfides with tributylphosphine". Methods Enzymol. Methods ... in the sense that TCEP does not regenerate-the end product of TCEP-mediated disulfide cleavage is in fact two free thiols/ ...
Disulfide Trisulfide Fujimori, Toshihiko; Morelos-Gómez, Aarón; Zhu, Zhen; Muramatsu, Hiroyuki; Futamura, Ryusuke; Urita, Koki ...
Disulfide bonds are broken. The B subunit remains in the endosome as a pore. The A subunit ADP-ribosylates host eEF-2. eEF-2 is ... Proteolytic nicking separates A and B subunits, which remain joined by disulfide bonds until they reach the cytosol. The toxin ... Diphtheria toxin is a single polypeptide chain of 535 amino acids consisting of two subunits linked by disulfide bridges, known ...
It is structurally similar to the more famous material molybdenum disulfide, MoS2. TaS2 is a semiconductor with d1 electron ... Revelli, J. F.; Disalvo, F. J. (1995). "Tantalum Disulfide (TaS2) and Its Intercalation Compounds". Inorganic Syntheses. ... Dunnill, Charles W.; MacLaren, Ian; Gregory, Duncan H. (2010). "Superconducting tantalum disulfide nanotapes; growth, structure ...
Damien, D.; Jove, J. (1971). "Americium disulfide and diselenide". Inorganic and Nuclear Chemistry Letters. 7 (7): 685. doi: ...
X. Intrachain disulfide bonds". Biochemistry. 9 (16): 3188-96. doi:10.1021/bi00818a011. PMID 4923144. Suter L, Barnikol HU, ... 3. The complete sequence and the location of the disulfide bridges". J. Biol. Chem. 244 (13): 3550-60. PMID 4893682. Gall WE, ...
Its presence was detected using positive ion mass spectrometry using a DART ion source and the disulfide dipyrithione [de] (2,2 ... "Bioactive Pyridine-N-oxide Disulfides from Allium stipitatum". J. Nat. Prod. 72 (3): 360-365. doi:10.1021/np800572r. PMC ...
... , in its simplest form, consists of two alpha and two beta chains, connected by disulfide bridges. The chains ... Malchy B, Dixon GH (1973). "Studies on the interchain disulfides of human haptoglobins". Can. J. Biochem. 51 (3): 249-64. doi: ...
Sri Siddhartha Medical College
Hypoglycemic effect of disulfides in experimental diabetes mellitus. Anti-atherosclerotic effect of disulphide in rats fed ...
Nuzzo, Ralph G.; Allara, David L. (31 May 1983). "Adsorption of bifunctional organic disulfides on gold surfaces". Journal of ...
"Adsorption of bifunctional organic disulfides on gold surfaces". Journal of the American Chemical Society. 105 (13): 4481-4483 ...
Many other organic S compounds affect the global sulfur cycle, including methanethiol , dimethyl disulfide, and carbon ... "Anaerobic respiration with elemental sulfur and with disulfides". FEMS Microbiology Reviews. 22 (5): 353-381. doi:10.1111/j. ... disulfide. Microorganisms that have sulfur-based metabolism represent a great opportunity for industrial processes, in ...
Homology to other disulfide oxidoreductases". J. Biol. Chem. 262 (36): 17313-8. PMID 3693355. Pons G, Raefsky-Estrin C, ... Additionally, DLD is a flavoenzyme oxidoreductase that contains a reactive disulfide bridge and a FAD cofactor that are ... functional similarities and divergent evolution of the pyridine nucleotide-disulfide oxidoreductases". Archives of Biochemistry ...
Phi value analysis
Wedemeyer, WJ; Welker, E; Narayan, M; Scheraga, HA (June 2000). "Disulfide bonds and protein folding". Biochemistry. 39 (23): ... value was used to study segment association in a folding transition state as covalent crosslinks like disulfide bonds were ...
... contains three disulfide bridges. Phoratoxin expresses different features that are typical for membrane active ...
Oxidation gives the disulfide (MBTS). This disulfide can react with amines to give sulfenamide derivatives such as DCBS and 2- ... The industrial route entails the high temperature reaction of aniline and carbon disulfide in the presence of sulfur, which ... Other routes developed by Hoffmann include the reactions of carbon disulfide with 2-aminophenol and of sodium hydrosulfide with ... Mercaptobenzothiazole disulfide (MBTS) Dicyclohexyl-2-benzothiazolesulfenamide (DCBS) Using MBT, rubber vulcanizes with less ...
Epidermal growth factor
This sequence contains six cysteine residues that form three intramolecular disulfide bonds. Disulfide bond formation generates ... Human EGF is 6-kDa and has 53 amino acid residues and three intramolecular disulfide bonds. EGF was originally described as a ... It contains three disulfide bridges. EGF, via binding to its cognate receptor, results in cellular proliferation, ...
... is 58 amino acid residues long and has a molecular mass of 6598 Da; it has 3 disulfide bridges. It has large homology ...
They are disulfide-rich peptides. Only two types are so far reported from two different species, the larger oxytoxin 1 (OxyTx1 ... It is a large peptide having a molecular mass of 8059.2 Da; but shows the size of 9,109.4 Da due to the presence of disulfide ... It is composed of 69 amino acid residue, which are cross-linked by five disulfide bridges. ...
... contains three disulfide bridges. Charybdotoxin occludes the pore of calcium-activated voltage-gated shaker K+ ...
Pregnancy-associated plasma protein A
Disulfide structure and carbohydrate attachment". The Journal of Biological Chemistry. 278 (4): 2106-17. doi:10.1074/jbc. ... "Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein ... "Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein ...
For example, it is an effective reagent for the desulfurization of organic disulfides. Trofimov, Boris A.; Arbuzova, Svetlana N ... Burns, John A.; Butler, James C.; Moran, John; Whitesides, George M. (1991). "Selective Reduction of Disulfides by Tris(2- ...
Dynamic covalent chemistry
Boronic acid condensation (BAC), and disulfide exchange constitute the two main reactions in this category. Disulfides can ... The application of disulfide chemistry has the added advantage of being a biological motif. Cysteine residues can form ... Some examples of this are shown in schemes 5 and 8, in an ester exchange, and disulfide exchange reactions. The second type, ... disulfide bonds in natural systems. Boronic acid self-condensation or condensation with diols is a well-documented dynamic ...
Disulfide - Wikipedia
... disulfide species". A disulfide ensemble is a grouping of all disulfide species with the same number of disulfide bonds, and is ... Disulfides where the two R groups are the same are called symmetric, examples being diphenyl disulfide and dimethyl disulfide. ... This process of disulfide rearrangement (known as disulfide shuffling) does not change the number of disulfide bonds within a ... for disulfide species having one, two, etc. disulfide bonds. Thus, the (26-84) disulfide species belongs to the 1S ensemble, ...
Hydrogen disulfide - Wikipedia
... hydrogen disulfide adds to alkenes to give disulfides and thiols. The deuterated form of hydrogen disulfide DSSD, has a similar ... Hydrogen disulfide has been described as "having a severe and irritating odour" that is similar to camphor or SCl 2, causing " ... Hydrogen disulfide is the inorganic compound with the formula H2S2. This hydrogen chalcogenide is a pale yellow volatile liquid ... Hydrogen disulfide can be synthesised by dissolving alkali metal or alkaline earth metal polysulfides in water. When the ...
Disulfide - Wikipedia
... disulfide species". A disulfide ensemble is a grouping of all disulfide species with the same number of disulfide bonds, and is ... Organic disulfides. A selection of disulfides FeS2,. "fools gold". S2Cl2,. a common industrial chemical. cystine,. ... a common organic disulfide. Symmetrical disulfides are compounds of the formula R2S2. Most disulfides encountered in organo ... This process of disulfide rearrangement (known as disulfide shuffling) does not change the number of disulfide bonds within a ...
Carbon Disulfide | NIOSH | CDC
Workers may be harmed by carbon disulfide. The level of exposure depends upon the dose, duration, and work being done. ... Carbon disulfide (CS2) is a colorless liquid with an ether-like odor. Exposure can cause dizziness, poor sleep, headache, ... EPA Acute Exposure Guideline Levels (AEGLs): Carbon Disulfideexternal icon. *EPA Chemistry Dashboard: Carbon Disulfideexternal ... IPCS INCHEM (CICADS) 46: Carbon Disulfideexternal icon. *IPCS INCHEM Environmental Health Criteria 10: Carbon Disulfideexternal ...
Carbon Disulfide | ToxFAQs™ | ATSDR
Carbon disulfide has been found in at least 210 of the 1,430 National Priorities List sites identified by the Environmental ... Exposure to carbon disulfide can occur by breathing it in the air and by drinking water or eating foods that contain it. ... What is carbon disulfide?. Pure carbon disulfide is a colorless liquid with a pleasant odor that is like the smell of ... How can carbon disulfide affect my health?. At very high levels, carbon disulfide may be life-threatening because of its ...
ICSC 1586 - DIMETHYL DISULFIDE
Evacuate danger area! Consult an expert! Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb liquid in sand or inert absorbent. Carefully collect remainder in sealable containers. Store and dispose of according to local regulations ...
carbon disulfide (CHEBI:23012)
Carbon Disulfide | Toxicological Profile | ATSDR
Occupational Exposure to Carbon Disulfide (77-156) | NIOSH | CDC
Appendix I - Air Sampling Method for Carbon Disulfide. X. Appendix II - Analytical Method for Carbon Disulfide. 77-156F.PDF (28 ... I. Recommendations for a Carbon Disulfide Standard. 77-156B.PDF (21 pages, 697K)pdf icon. ... Criteria for a Recommended Standard: Occupational Exposure to Carbon Disulfide. ... Appendix III - Method of Biologic Monitoring for Carbon Disulfide: Iodine-Azide Test. ...
Tire and Rubber Company - Carbon disulfide Exposure | NIOSH | CDC
The exposure under study was carbon disulfide, a chemical used in rubber chemicals department. ... Carbon disulfide exposures at the plant were not found at levels associated with heart disease and the chemical was removed ... Tire and Rubber Company (1) (Carbon disulfide Exposure). 2001. Study Background. NIOSH conducted a study of workers at a tire ... Some studies suggest that carbon disulfide, a chemical used in making rubber chemicals, may increase the risk of heart disease ...
Diffusion coefficient of hexane in carbon disulfide | SpringerLink
This chapter provides the diffusion coefficient of hexane in carbon disulfide at different concentrations measured using ... Winkelmann J. (2018) Diffusion coefficient of hexane in carbon disulfide. In: Lechner M.D. (eds) Diffusion in Gases, Liquids ... This chapter provides the diffusion coefficient of hexane in carbon disulfide at different concentrations measured using ...
Diameter-dependent wetting of tungsten disulfide nanotubes | PNAS
2013) Tungsten disulfide nanotubes reinforced biodegradable polymers for bone tissue engineering. Acta Biomater 9(9):8365-8373. ... Diameter-dependent wetting of tungsten disulfide nanotubes. Ohad Goldbart, Sidney R. Cohen, Ifat Kaplan-Ashiri, Polina ... Here, we present a comprehensive wetting study of individual tungsten disulfide nanotubes by water. We reveal the nature of ... We have studied the wetting of individual, size-selected tungsten disulfide nanotubes, both experimentally and theoretically. ...
Crystal structure of tetraisobutylthiuram disulfide: Ingenta Connect
Tetraisobutylthiuram disulfide molecules of one optical configuration form sheets in the plane of the a and b axes. Inversion ... Tetrakis(2-methylpropyl)thioperoxydicarbonic diamide, or tetraisobutylthiuram disulfide, C18H36N2S4, crystallizes in a general ... position in the triclinic space group P-1 but shows pseudo-C2 symmetry about the disulfide bond. The C-S-S-C torsion angle [− ...
Ultrahigh-current-density niobium disulfide catalysts for hydrogen evolution | Nature Materials
Here, we report the synthesis of the metallic 2H phase of niobium disulfide with additional niobium (2H Nb1+xS2, where x is ~ ... The metallic 2H phase of niobium disulfide now exhibits enhanced current densities versus a reversible hydrogen electrode. ... Here, we report the synthesis of the metallic 2H phase of niobium disulfide with additional niobium (2H Nb1+xS2, where x is ~ ... Yang, J., Mohmad, A.R., Wang, Y. et al. Ultrahigh-current-density niobium disulfide catalysts for hydrogen evolution. Nat. ...
Protein Disulfide Isomerases
... is a multifunctional protein that facilitates the formation of correct disulfide crosslinks between cysteine residues during ... The catalysis of disulfide formation relies almost entirely on the high reactivity of PDIs active site disulfides. However, ... Catalysis of disulfide isomerisation. Disulfide isomerisation is initiated by attack of the nucleophilic cysteine of the PDI. ... Protein disulfide isomerase (PDI) is a multifunctional protein that facilitates the formation of correct disulfide crosslinks ...
Disulfide Bonds: Key to Wheat Protein Functionality | SpringerLink
Disulfide bonds in wheat proteins are major factors that determine the properties of the proteins and their functionality in ... Disulfide Bond Bread Wheat Wheat Flour Mercuric Chloride Glutenin Subunit These keywords were added by machine and not by the ... Disulfide bonds in wheat proteins are major factors that determine the properties of the proteins and their functionality in ... Huebner F.R., Bietz J.A., Wall J.S. (1977) Disulfide Bonds: Key to Wheat Protein Functionality. In: Friedman M. (eds) Protein ...
Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits | PNAS
Inter-subunit disulfide bonds also produced some ASIC1a complexes larger than trimers. Inter-subunit disulfide bond formation ... ASIC1a Forms Inter-Subunit Disulfide Bonds in Vivo.. To learn if ASIC1a forms inter-subunit disulfide links in vivo, we blotted ... ASIC1a Forms Inter-Subunit Disulfide Bonds.. To learn whether inter-subunit disulfide bonds might contribute to the multimeric ... of surface subunits were linked by inter-subunit disulfide bonds. These data indicate that disulfide linkage between ASIC1a ...
The molar heat of vaporization of carbon disulfide, | bartleby
NTU research team discovers optoelectronic application for molybdenum disulfide
Disulfide content of reduced hen ... preview & related info | Mendeley
Disulfide content of reduced hen egg white and human milk lysozymes during the folding process. *Perraudin J ... Following disulfide bond formation, under identical conditions, similar products were found during the folding of both ... Perraudin, J. P., Guillard, R., Prieels, J. P., Torchia, T., & Thierry, D. (1983). Disulfide content of reduced hen egg white ...
Aqueous Medium Synthesis Route for Randomly Stacked Molybdenum Disulfide
Molybdenum disulfide (MoS2) is a hexagonal layer structured material. The MoS2 layers, each of which consists of a layer of ... R. N. Viswanath and S. Ramasamy, "Preparation and isochronal sintering behavior of molybdenum disulfide compound," Journal of ... R. R. Chianelli, E. B. Prestridge, T. A. Pecoraro, and J. P. Deneufville, "Molybdenum disulfide in the poorly crystalline "rag ... K. I. Tanaka and T. Okuhara, "Regulation of intermediates on sulfided nickel and molybdenum disulfide catalysts," Catalysis ...
Disulfides | Molecular and Cellular Biology
Role of Disulfide Bridges Formed in the Luminal Domain of ATF6 in Sensing Endoplasmic Reticulum Stress Satomi Nadanaka, Tetsuya ... Intramolecular Disulfide Bonds of the Prolactin Receptor Short Form Are Required for Its Inhibitory Action on the Function of ... Mixed-Disulfide Folding Intermediates between Thyroglobulin and Endoplasmic Reticulum Resident Oxidoreductases ERp57 and ... Protein Disulfide Isomerase Bruno Di Jeso, Young-nam Park, Luca Ulianich, A. Sonia Treglia, Malene L. Urbanas, Stephen High, ...
Kanazawa University Research: Opposite Piezoresistant Effects of Rhenium Disulfide in two Principle Directions
PRNewswire/ -- Using optical and electrical measurements, a two-dimensional anisotropic crystal of rhenium disulfide was found ... Rhenium disulfide (ReS2) is a two-dimensional (2D) material crystallizing into a flake-like structure, as a black platelet ( ... Kanazawa University Research: Opposite Piezoresistant Effects of Rhenium Disulfide in two Principle Directions ... This novel finding is expected to lead to wide application of rhenium disulfide. ...
Dimethyl disulfide ≥99.0% | Methyl disulfide | Sigma-Aldrich
Methyl disulfide; Linear Formula: CH3SSCH3; Empirical Formula: C2H6S2; find related products, papers, technical documents, MSDS ... Dimethyl disulfide (DMDS) is an organic dialkyl disulfide. It is one of the odorous compounds found on the working face of ... Dimethyl disulfide (DMDS) may be used to derivatize alkenes for the determination of position of double bond by MS. It may also ... Nutrition Research, Organic Building Blocks, Phytochemicals by Plant (Food/Spice/Herb), Sulfides/Disulfides, Sulfur Compounds ...
Bis((4-ethyl-1-piperazinyl)thiocarbonyl)disulfide BRN 0831511 DISULFIDE, BIS((4-ETHYL-1-PIPERAZINYL)THIOCARBONYL) (4- ... DISULFIDE, BIS((4-ETHYL-1-PIPERAZINYL)THIOCARBONYL)
- In the laboratory, iodine in the presence of base is commonly employed to oxidize thiols to disulfides. (wikipedia.org)
- Reagents that deliver the equivalent of "RS+" react with thiols to give asymmetrical disulfides: RSH + R′SNR″2 → RS−SR′ + HNR″2 where R″2N is the phthalimido group. (wikipedia.org)
- In organosulfur chemistry, hydrogen disulfide adds to alkenes to give disulfides and thiols. (wikipedia.org)
- In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′. The linkage is also called an SS-bond or sometimes a disulfide bridge and is usually derived by the coupling of two thiol groups. (wikipedia.org)
- In biology, disulfide bridges formed between thiol groups in two cysteine residues are an important component of the secondary and tertiary structure of proteins. (wikipedia.org)
- The structure of hydrogen disulfide is similar to that of hydrogen peroxide, with C2 point group symmetry. (wikipedia.org)
- Click here for the Molybdenum Disulfide SDS . (lesker.com)
- Molybdenum disulfide is a chemical compound that looks like a dark gray mineral with a metallic sheen and is soft and oily to the touch. (tecnolubeseal.it)
- TecnolubeSeal has a full range of molybdenum disulfide lubricants. (tecnolubeseal.it)
- Rheolube 380: synthetic grease with molybdenum disulfide ideal for lubricating screw balls and/or medium and small gears. (tecnolubeseal.it)
- Fluorocarbongel 880 MS: high viscosity silicone grease able to withstand high loads due to the combination of PTFE and molybdenum disulfide. (tecnolubeseal.it)
- Fluorocarbongel 875 MS: PAO-base grease with molybdenum disulfide, ideal for kinematic lifetime lubrication lenses such as fifth wheels, gears and/or bearings. (tecnolubeseal.it)
- Molybdenum Disulfide is a superior dry lubricant with dozens of uses. (runawaybike.com)
- Formulated with Molybdenum Disulfide, a compound that helps satisfy the severe lubrication requirements of heavy-duty industrial and construction equipment as well as automotive and/or heavy-duty vehicle applications, Moly Grease serves to lubricate and protect sliding surfaces and/or surfaces under great pressure. (petroleumservicecompany.com)
- The Molybdenum Disulfide molecules form protective layers that prevent metal-to-metal contact and smooth out the surfaces in operation, thus reducing operating temperatures and friction. (petroleumservicecompany.com)
- Molybdenum disulfide is the main component of molybdenite-solid black powder with a metallic luster. (whatsontianjin.com)
- 4. Due to the low friction coefficient of the molybdenum disulfide , the frictional resistance generated between the friction devices is small, which can save electricity. (whatsontianjin.com)
- 6. The application of molybdenum disulfide lubrication solves the technical key and improves the working efficiency and working precision. (whatsontianjin.com)
- 7. Molybdenum disulfide has the function of filling and filling, can restore the geometric dimensions of some parts, and extend the service life. (whatsontianjin.com)
- 8. Molybdenum disulfide has the characteristics of moisture-proof, waterproof, alkali proof, and acid-proof. (whatsontianjin.com)
- 9. Using molybdenum disulfide plastic or powder to smelt molded parts can save a lot of non-ferrous metals. (whatsontianjin.com)
- 10. After using molybdenum disulfide lubrication in some equipment, the complex oil supply system can be omitted, which significantly simplifies the structure of the material, relatively improves the effective area utilization rate, and will also cause significant reforms-equipment design. (whatsontianjin.com)
- 11. Molybdenum disulfide also has its disadvantages, such as poor thermal conductivity, insufficient friction coefficient, and low permeability (compared to dilute oil). (whatsontianjin.com)
- Solid lubricants composites based by Graphite, Molybdenum Disulfide, etc. are used in the forms of sintered alloys, dry films, or liquid films being dispersed in oil at various sliding contacts. (fujipress.jp)
- Associate Professor Justin Ye, head of the Device Physics of Complex Materials group at the University of Groningen, studied superconductivity in a double layer of molybdenum disulfide and discovered new superconducting states. (rug.nl)
- Superconductivity has been shown in monolayer crystals of, for example, molybdenum disulphide or tungsten disulfide that have a thickness of just three atoms. (rug.nl)
- Ye and his collaborators studied a double layer of molybdenum disulfide: 'In that configuration, the interaction between the two layers creates new superconducting states. (rug.nl)
- This is a schematic (top) and SEM picture (bottom) of the suspended double layer of molybdenum disulfide with ionic liquid gating. (rug.nl)
- With the suspended bilayer of molybdenum disulfide, Ye and collaborators have all the ingredients needed to study some special superconducting states. (rug.nl)
- Rather than silica, he experiments with molybdenum disulfide nanotubes, which mix well with oil. (wearechange.org)
- Small size Monolayer Tungsten disulfide will be supplied as powder or dispersion‚ and it has good solubility in water and ethanol. (acsmaterial.com)
- Dibenzothiazole Disulfide Detailed Dibenzothiazole Disulfide Description Features: a) Molecular formula: C14H8N2S4 b) Molecular weight: 332.50 c) Technical specification: GB / T 11408 - 2003 d) Appearance: white or light yellow powder or granular e) Melting point: 166.0 o C (min. (nijmegen-nieuws.nl)
- Rubber Accelerator MBTS(DM) Chemical Name 2, 2-Dibenzothiazole Disulfide (MBTS) Molecular Formula C14H8N2S4 Molecular Weight 332.5 CAS No. 120-78-5 Specifications GB/T 11408-2013 ItemSpecifications High grade AppearanceWhite or light yellow powder or Granular Initial Melting Point (℃)Min.170.0 Fin. (nijmegen-nieuws.nl)
- In this study an effect of inorganic fullerene-like tungsten disulfide nanoparticles (IF-WS2) in aramid/phenolic resin/PVB composite for improving its viscoelastic and mechanical properties is examined. (ac.rs)
- The dispersion concentration of small size Monolayer Tungsten disulfide in water will be adjustable in 0.1mg - 1 mg/ml. (acsmaterial.com)
- Mechanically deposited tungsten disulfide saturable absorber for low-threshold Q-switched erbium-doped fiber laser. (acsmaterial.com)
- abstract = "Tungsten disulfide (WS2) is a layered transition metal dichalcogenide with a reported band gap of 1.8 eV in bulk and 1.32-1.4 eV in its thin film form. (edu.sa)
- Even in the strongest static magnetic field in Europe, which has a strength of 37 Tesla, the superconductivity in tungsten disulfide does not show any change. (rug.nl)
- Carbon disulfide is a colorless volatile liquid chemical with formula CS 2 and CAS number 75-15-0. (worldofchemicals.com)
- Carbon disulfide is commercially prepared by sulfur reaction with charcoal or methane, ethane, propane and propene are used to prepare it to a limited extent. (worldofchemicals.com)
- Carbon disulfide appears as a colorless to the light yellow liquid compound. (worldofchemicals.com)
- Carbon disulfide has melting point of -111.61 degree Celsius and boiling point of 46.24 degree Celsius. (worldofchemicals.com)
- Carbon disulfide has an ether-like or chloroform odor and commercially foul smell. (worldofchemicals.com)
- The principal use of carbon disulfide is in the manufacturing of rayon and cellophane. (worldofchemicals.com)
- Carbon disulfide is an important intermediate in carbon tetrachloride chemical synthesis. (worldofchemicals.com)
- Carbon disulfide suppliers , manufacturers or buyers need to consider some safety in handling and storage guides when they buy carbon disulfide . (worldofchemicals.com)
- Store carbon disulfide in a cool, dry and well-ventilated place. (worldofchemicals.com)
- In case of contact of carbon disulfide with skin or hair, remove contaminated clothing and drench affected area with plenty of water. (worldofchemicals.com)
- Global Reach- We are an online portal with carbon disulfide suppliers, manufacturers and exporters listed from across the globe. (worldofchemicals.com)
- Quality Assurance: With our verified list of carbon disulfide suppliers we ensure the quality of the carbon disulfide. (worldofchemicals.com)
- Fast Processing: Our experts process the enquiries quickly, connecting genuine buyers and suppliers of carbon disulfide. (worldofchemicals.com)
- Vapors: ethyl alcohol, carbon disulfide, acetone. (petzl.com)
- The "negative signature mass" process is different from the conventional approach in that it does not directly rule-in disulfide linkages, but rather eliminates linkages from a list of all possible theoretical linkages, with the goal of ruling out enough linkages so that only one disulfide structure can be constructed. (elsevier.com)
- Well-defined reductively degradable amphiphilic block copolymers having disulfide linkages positioned repeatedly on hydrophobic chains, thus exhibiting fast degradation, were prepared by a combination of polycondensation and ATRP . (rsc.org)
- their degradation rate was significantly enhanced with the increasing amounts of disulfide linkages in ssPES-OH and reducing agents . (rsc.org)
- 2-Merceptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis. (thomassci.com)
- FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. (uniprot.org)
- Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. (sigmaaldrich.com)
- Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure. (sigmaaldrich.com)
- Recombinant protein expression may produce aberrant disulfide bonds and could result in safety concerns or decreased efficacy. (ku.edu)
- The use of ETD facilitates this analysis because disulfide bonds are preferentially cleaved when subjected to ETD. (ku.edu)
- It was found that one region of the protein, the V1/V2 loops, had significant heterogeneity in the disulfide bonds. (ku.edu)
- Proper localization of disulfide bonds also facilitates the prediction of protein three-dimensional (3D) structure. (proteinpeptideletters.com)
- However, it is both time-consuming and labor-intensive using conventional experimental approaches to determine disulfide bonds, especially for large-scale data sets. (proteinpeptideletters.com)
- Interestingly, comparison of top features between interand intra-chain disulfide bonds revealed the similarities and differences of the mechanisms of forming these two types of disulfide bonds, which might help understand more of the mechanisms and provide clues to further experimental studies in this research field. (proteinpeptideletters.com)
- 2-Merceptoethanol is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. (thomassci.com)
- References disulfide_atom_indices_ , disulfide_info_ , disulfide_partners_ , disulfide_residue_types_ , empty() , and resid_2_disulfide_index_ . (rosettacommons.org)
- The operating principles and the effectiveness of the algorithm are described in the context of analyzing ribonuclease A, a 124-residue protein containing eight cysteines in the form of four cystines (disulfides). (elsevier.com)
- Find a host of high-grade, pure and colorless dibenzothiazole disulfide c14h8n2s4 at Alibaba.com for various chemical and pharmaceutical purposes. (nijmegen-nieuws.nl)
- Increasing interest in production of protein-based pharmaceuticals (biotherapeutics) is accompanied by an increased need for verification of protein folding and correct disulfide bonding. (ku.edu)
- Thus, the thorough analysis of disulfide bonding is a necessity for protein therapeutics. (ku.edu)
- The method was applied for assigning the disulfide-bonding network of a recombinant monomer of the HIV envelope protein gp120. (ku.edu)
- Protein disulfide bond is formed during post-translational modifications, and has been implicated in various physiological and pathological processes. (proteinpeptideletters.com)
- The genomics of disulfide bonding and protein stabilization in thermophiles. (ucla.edu)
- Here, we have tried to enhance the stability of the BNCs because the L-proteins in the BNCs were aggregated due to random disulfide bridging when stored for a long period at 4 °C. The envelope protein contains fourteen cysteine residues in the S domain. (fujita-hu.ac.jp)
- Here, the concept of "negative signature mass" is introduced as the novel feature of an algorithm designed to identify the disulfide structure of a cystinyl protein given an input of mass spectral data and an amino acid sequence. (elsevier.com)
- WESTCO™ TBzTD Accelerator Tetrabenzylthiuram disulfide CAS# 10591-85-2 WESTCO™ TBzTD is a fast curing primary or secondary accelerator for NR, SBR and NBR with long scorch times and low to nil nitrosamine generation during vulcanization. (madebyaniek.nl)
- Alibaba.com offers 875 dibenzothiazole disulfide mbts products. (nijmegen-nieuws.nl)
- Here, we make use of this well-characterized reaction to assign disulfide bonding networks by coupling the use of extracted ion chromatograms (XICs) of cysteine-containing peptides with ETD analysis to produce an efficient assignment approach for disulfide bonding. (ku.edu)
- Human acid sphingomyelinase - Assignment of the disulfide bond pattern. (mpg.de)
- The above is the search results for Chinese Dm, click for more recommended manufacturers & suppliers listings such as mbts, dibenzothiazole disulfide, antioxidant. (nijmegen-nieuws.nl)
- When freed from the constraints of a disulfide link to Cys-43, Cys-40 pivots to become slightly more solvent-accessible. (rcsb.org)
- Our approach achieves a prediction accuracy of 0.8702 for inter-chain disulfide bond prediction using 128 features and 0.9219 for intra-chain disulfide bond prediction using 261 features. (proteinpeptideletters.com)
- Features of sequence conservation, residual disorder, and amino acid factor are used for inter-chain disulfide bond prediction. (proteinpeptideletters.com)
- An efficient method for data processing and interpretation is needed to support and extend disulfide mass-mapping methodology based on partial reduction and cyanylation-induced cleavage to proteins containing more than four cystines. (elsevier.com)
- However, in addition to iron-disulfides (such as pyrite), ASS landscapes often contain large amounts of iron-monosulfide minerals. (edu.au)
- A wide variety of dibenzothiazole disulfide mbts options are available to you, such as classification, usage, and type. (nijmegen-nieuws.nl)
- 10591-85-2, Tetrabenzylthiuram Disulfide, Benzyl Tuex manufacturer / supplier in China, offering Tetrabenzylthiuram Disulfide Tbztd (CAS No. 10591-85-2), 3-Acryloxypropyltrimethoxysilane, CAS: 4369-14-6, UV Absorbent UV-531 CAS: 1843-05-6 Light Stabilizer and so on. (madebyaniek.nl)
- Analysis of optimal feature set indicated key features and key sites for the disulfide bond formation. (proteinpeptideletters.com)
- Therefore, investigation of thiol disulfide balance with presented method represents a new promising test for early diagnosis and management of women at high risk for cervical cancer. (researchsquare.com)
- Since there are also some limitations for disulfide bond prediction based on 3D structure features, developing sequence-based, convenient and fast-speed computational methods for both inter- and intra-chain disulfide bond prediction is necessary. (proteinpeptideletters.com)
- This method can be used to assign a disulfide pattern in a de novo fashion, to detect disulfide shuffling, and to provide information on heterogeneity, when more than one disulfide bonding pattern is present. (ku.edu)
- In this study, we developed a computational method for both types of disulfide bond prediction based on maximum relevance and minimum redundancy (mRMR) method followed by incremental feature selection (IFS), with nearest neighbor algorithm as its prediction model. (proteinpeptideletters.com)
- Support for Disulfides. (bakerlab.org)
- And in addition to these features, sequential distance between a pair of cysteines is also used for intra-chain disulfide bond prediction. (proteinpeptideletters.com)