Thrombosis. Medical search

Formation and development of a thrombus or blood clot in the blood vessel.

The formation or presence of a blood clot (THROMBUS) within a vein.

Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.

Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.

Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.

Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.

Agents that prevent clotting.

Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.

Radiographic visualization or recording of a vein after the injection of contrast medium.

Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.

A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.

A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.

DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.

A short thick vein formed by union of the superior mesenteric vein and the splenic vein.

Veins draining the cerebrum.

A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.

The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.

Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.

Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)

The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.

The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.

Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.

Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.

Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.

Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis.

Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.

The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.

Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.

Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.

Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.

Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.

Bleeding or escape of blood from a vessel.

Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.

An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)

Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).

A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.

A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.

Elements of limited time intervals, contributing to particular results or situations.

Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Short thick veins which return blood from the kidneys to the vena cava.

Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.

Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.

A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.

An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

The natural enzymatic dissolution of FIBRIN.

The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.

Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.

A condition caused by one or more episodes of DEEP VEIN THROMBOSIS, usually the blood clots are lodged in the legs. Clinical features include EDEMA; PAIN; aching; heaviness; and MUSCLE CRAMP in the leg. When severe leg swelling leads to skin breakdown, it is called venous STASIS ULCER.

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.

Obstruction of flow in biological or prosthetic vascular grafts.

A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.

Mechanical devices inserted in the inferior vena cava that prevent the migration of blood clots from deep venous thrombosis of the leg.

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.

Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.

Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.

The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.

The return of a sign, symptom, or disease after a remission.

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Laboratory tests for evaluating the individual's clotting mechanism.

Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

Catheters designed to be left within an organ or passage for an extended period of time.

Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.

Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.

A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.

Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.

Endogenous substances, usually proteins, that are involved in the blood coagulation process.

Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)

The degree to which BLOOD VESSELS are not blocked or obstructed.

The vessels carrying blood away from the capillary beds.

Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.

Disease having a short and relatively severe course.

A subnormal level of BLOOD PLATELETS.

The long large endothelium-lined venous channel on the top outer surface of the brain. It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. Near the lower back of the CRANIUM, the superior sagittal sinus deviates to one side (usually the right) and continues on as one of the TRANSVERSE SINUSES.

The plan and delineation of prostheses in general or a specific prosthesis.

The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.

The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.

A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.

Recording changes in electrical impedance between electrodes placed on opposite sides of a part of the body, as a measure of volume changes in the path of the current. (Stedman, 25th ed)

Material used for wrapping or binding any part of the body.

Instruments that generate intermittent forces, uniformed or graduated, to facilitate the emptying of VEINS. These devices are used to reduce limb EDEMA and prevent venous THROMBOEMBOLISM, such as deep vein thrombosis in the legs.

Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.

A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

The process whereby PLATELETS adhere to something other than platelets, e.g., COLLAGEN; BASEMENT MEMBRANE; MICROFIBRILS; or other "foreign" surfaces.

Radiography of blood vessels after injection of a contrast medium.

The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)

The number of PLATELETS per unit volume in a sample of venous BLOOD.

A heparin fraction with a mean molecular weight of 4500 daltons. It is isolated from porcine mucosal heparin and used as an antithrombotic agent. (From Merck Index, 11th ed)

The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

Radiography of the vascular system of the heart muscle after injection of a contrast medium.

Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.

A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.

The condition of an anatomical structure's being constricted beyond normal dimensions.

A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.

Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.

Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)

Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.

The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.

Inorganic or organic compounds containing trivalent iron.

A cell surface glycoprotein of endothelial cells that binds thrombin and serves as a cofactor in the activation of protein C and its regulation of blood coagulation.

Agents capable of exerting a harmful effect on the body.

Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

Radiography of the vascular system of the brain after injection of a contrast medium.

Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.

Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.

Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells.

Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.

Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.

Increased numbers of platelets in the peripheral blood. (Dorland, 27th ed)

The main artery of the thigh, a continuation of the external iliac artery.

Operative procedures for the treatment of vascular disorders.

Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

A coumarin that is used as an anticoagulant. Its actions and uses are similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p233)

A deficiency of blood coagulation factor V (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait. (Dorland, 27th ed)

Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.

Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Extracellular vesicles generated by the shedding of CELL MEMBRANE blebs.

Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.

A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.

Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.

Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.

A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.

Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.

Enlarged and tortuous VEINS.

Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.

The transference of a part of or an entire liver from one human or animal to another.

A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.

Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.

Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.

A subclass of purinergic P2Y receptors that have a preference for ADP binding and are coupled to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI. The P2Y12 purinergic receptors are found in PLATELETS where they play an important role regulating PLATELET ACTIVATION.

A collective term for pathological conditions which are caused by the formation of a blood clot (THROMBUS) in a blood vessel, or by blocking of a blood vessel with an EMBOLUS, undissolved materials in the blood stream.

Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.

The veins and arteries of the HEART.

Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.

Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.

The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.

Surgical venous shunt between the portal and systemic circulation to effect decompression of the portal circulation. It is performed primarily in the treatment of bleeding esophageal varices resulting from portal hypertension. Types of shunt include portacaval, splenorenal, mesocaval, splenocaval, left gastric-caval (coronary-caval), portarenal, umbilicorenal, and umbilicocaval.

A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.

The time required by whole blood to produce a visible clot.

Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.

Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.

Surgical procedure involving either partial or entire removal of the spleen.

A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.

Substances, usually endogenous, that act as inhibitors of blood coagulation. They may affect one or multiple enzymes throughout the process. As a group, they also inhibit enzymes involved in processes other than blood coagulation, such as those from the complement system, fibrinolytic enzyme system, blood cells, and bacteria.

Laboratory examination used to monitor and evaluate platelet function in a patient's blood.

A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.

Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.

Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.

Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.

Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.

Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

The vessels carrying blood away from the heart.

The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)

Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

An absence or reduced level of blood coagulation factor XII. It normally occurs in the absence of patient or family history of hemorrhagic disorders and is marked by prolonged clotting time.

A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

The vein which drains the foot and leg.

Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.

A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)

Use of HIRUDINS as an anticoagulant in the treatment of cardiological and hematological disorders.

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Narrowing or constriction of a coronary artery.

Systemic infection with Alaria americana (Trematoda). (1/5349)

Alaria americana is a trematode, the adult of which is found in mammalian carnivores. The first case of disseminated human infection by the mesocercarial stage of this worm occurred in a 24-year-old man. The infection possibly was acquired by the eating of inadequately cooked frogs, which are intermediate hosts of the worm. The diagnosis was made during life by lung biopsy and confirmed at autopsy. The mesocercariae were present in the stomach wall, lymph nodes, liver, myocardium, pancreas and surrounding adipose tissue, spleen, kidney, lungs, brain and spinal cord. There was no host reaction to the parasites. Granulomas were present in the stomach wall, lymph nodes and liver, but the worms were not identified in them. Hypersensitivity vasculitis and a bleeding diathesis due to disseminated intravascular coagulation and a circulating anticoagulant caused his death 8 days after the onset of his illness. (+info)

Antiphospholipid, anti-beta 2-glycoprotein-I and anti-oxidized-low-density-lipoprotein antibodies in antiphospholipid syndrome. (2/5349)

Antiphospholipid antibodies (aPL), anti-beta 2-glycoprotein I (anti-beta 2-GPI) and anti-oxidized-low-density lipoprotein (LDL) antibodies are all implicated in the pathogenesis of antiphospholipid syndrome. To investigate whether different autoantibodies or combinations thereof produced distinct effects related to their antigenic specificities, we examined the frequencies of antiphospholipid syndrome (APS)-related features in the presence of different antibodies [aPL, beta 2-GPI, anti-oxidized low density lipoprotein (LDL)] in 125 patients with APS. Median follow-up was 72 months: 58 patients were diagnosed as primary APS and 67 as APS plus systemic lupus erythematosus (SLE). Anticardiolipin antibodies (aCL), anti-beta 2-GPI and anti-oxidized LDL antibodies were determined by ELISA; lupus anticoagulant (LA) by standard coagulometric methods. Univariate analysis showed that patients positive for anti-beta 2-GPI had a higher risk of recurrent thrombotic events (OR = 3.64, 95% CI, p = 0.01) and pregnancy loss (OR = 2.99, 95% CI, p = 0.004). Patients positive for anti-oxidized LDL antibodies had a 2.24-fold increase in the risk of arterial thrombosis (2.24, 95% CI, p = 0.03) and lower risk of thrombocytopenia (OR = 0.41 95% CI, p = 0.04). Patients positive for aCL antibodies had a higher risk of pregnancy loss (OR = 4.62 95% CI, p = 0.001). When these data were tested by multivariate logistic regression, the association between anti-beta 2-GPI and pregnancy loss and the negative association between anti-oxidized LDL antibodies and thrombocytopenia disappeared. (+info)

Blood-borne tissue factor: another view of thrombosis. (3/5349)

Arterial thrombosis is considered to arise from the interaction of tissue factor (TF) in the vascular wall with platelets and coagulation factors in circulating blood. According to this paradigm, coagulation is initiated after a vessel is damaged and blood is exposed to vessel-wall TF. We have examined thrombus formation on pig arterial media (which contains no stainable TF) and on collagen-coated glass slides (which are devoid of TF) exposed to flowing native human blood. In both systems the thrombi that formed during a 5-min perfusion stained intensely for TF, much of which was not associated with cells. Antibodies against TF caused approximately 70% reduction in the amount of thrombus formed on the pig arterial media and also reduced thrombi on the collagen-coated glass slides. TF deposited on the slides was active, as there was abundant fibrin in the thrombi. Factor VIIai, a potent inhibitor of TF, essentially abolished fibrin production and markedly reduced the mass of the thrombi. Immunoelectron microscopy revealed TF-positive membrane vesicles that we frequently observed in large clusters near the surface of platelets. TF, measured by factor Xa formation, was extracted from whole blood and plasma of healthy subjects. By using immunostaining, TF-containing neutrophils and monocytes were identified in peripheral blood; our data raise the possibility that leukocytes are the main source of blood TF. We suggest that blood-borne TF is inherently thrombogenic and may be involved in thrombus propagation at the site of vascular injury. (+info)

Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. (4/5349)

The perivascular implantation of tissue-engineered endothelial cells around injured arteries offers an opportunity to study fundamental vascular physiology as well as restore and improve tissue function. Cell source is an important issue because the ability to implant either xenogeneic or allogeneic cells would greatly enhance the clinical applications of tissue-engineered grafts. We investigated the biological and immunological responses to endothelial cell xenografts and allografts in pigs 4 weeks after angioplasty of the carotid arteries. Porcine or bovine aortic endothelial cells were cultured within Gelfoam matrices and implanted in the perivascular space of 42 injured arteries. Both porcine and bovine endothelial cell grafts reduced the restenosis index compared with control by 54% and 46%, respectively. Perivascular heparin release devices, formulated to release heparin at twice the rate of release of heparan sulfate proteoglycan from endothelial cell implants, produced no significant reduction in the restenosis index. Endothelial cell implants also reduced occlusive thrombosis compared with control and heparin release devices. Host immune responses to endothelial implants were investigated by immunohistochemical examination of explanted devices and by immunocytochemistry of serum samples. The bovine cell grafts displayed infiltration of leukocytes, consisting primarily of lymphocytes, and caused an increase in antibodies detected in serum samples. Reduced cellular infiltration and no humoral response were detected in animals that received allografts. Despite the difference in immune response, the biological effects of xenografts or allografts did not differ significantly. (+info)

The tourniquet in total knee arthroplasty. A prospective, randomised study. (5/5349)

We assessed the influence of the use of a tourniquet in total knee arthroplasty in a prospective, randomised study. After satisfying exclusion criteria, we divided 77 patients into two groups, one to undergo surgery with a tourniquet and one without. Both groups were well matched. The mean change in knee flexion in the group that had surgery without a tourniquet was significantly better at one week (p = 0.03) than in the other group, but movement was similar at six weeks and at four months. There was no significant difference in the surgical time, postoperative pain, need for analgesia, the volume collected in the drains, postoperative swelling, and the incidence of wound complications or of deep-venous thrombosis. We conclude that the use of a tourniquet is safe and that current practice can be continued. (+info)

The value of late computed tomographic scanning in identification of vascular abnormalities after abdominal aortic aneurysm repair. (6/5349)

PURPOSE: The purpose of this study was to determine the prevalence of late arterial abnormalities after aortic aneurysm repair and thus to suggest a routine for postoperative radiologic follow-up examination and to establish reference criteria for endovascular repair. METHODS: Computed tomographic (CT) scan follow-up examination was obtained at 8 to 9 years after abdominal aortic aneurysm (AAA) repair on a cohort of patients enrolled in the Canadian Aneurysm Study. The original registry consisted of 680 patients who underwent repair of nonruptured AAA. When the request for CT scan follow-up examination was sent in 1994, 251 patients were alive and potentially available for CT scan follow-up examination and 94 patients agreed to undergo abdominal and thoracic CT scanning procedures. Each scan was interpreted independently by two vascular radiologists. RESULTS: For analysis, the aorta was divided into five defined segments and an aneurysm was defined as a more than 50% enlargement from the expected normal value as defined in the reporting standards for aneurysms. With this strict definition, 64.9% of patients had aneurysmal dilatation and the abnormality was considered as a possible indication for surgical repair in 13.8%. Of the 39 patients who underwent initial repair with a tube graft, 12 (30.8%) were found to have an iliac aneurysm and six of these aneurysms (15.4%) were of possible surgical significance. Graft dilatation was observed from the time of operation (median graft size of 18 mm) to a median size of 22 mm as measured by means of CT scanning at follow-up examination. Fluid or thrombus was seen around the graft in 28% of the cases, and bowel was believed to be intimately associated with the graft in 7%. CONCLUSION: Late follow-up CT scans after AAA repair often show vascular abnormalities. Most of these abnormalities are not clinically significant, but, in 13.8% of patients, the thoracic or abdominal aortic segment was aneurysmal and, in 15.4% of patients who underwent tube graft placement, one of the iliac arteries was significantly abnormal to warrant consideration for surgical repair. On the basis of these findings, a routine CT follow-up examination after 5 years is recommended. This study provides a population-based study for comparison with the results of endovascular repair. (+info)

Immunohistochemical analysis of arterial wall cellular infiltration in Buerger's disease (endarteritis obliterans). (7/5349)

PURPOSE: The diagnosis of Buerger's disease has depended on clinical symptoms and angiographic findings, whereas pathologic findings are considered to be of secondary importance. Arteries from patients with Buerger's tissue were analyzed histologically, including immunophenotyping of the infiltrating cells, to elucidate the nature of Buerger's disease as a vasculitis. METHODS: Thirty-three specimens from nine patients, in whom Buerger's disease was diagnosed on the basis of our clinical and angiographic criteria between 1980 and 1995 at Nagoya University Hospital, were studied. Immunohistochemical studies were performed on paraffin-embedded tissue with a labeled streptoavidin-biotin method. RESULTS: The general architecture of vessel walls was well preserved regardless of the stage of disease, and cell infiltration was observed mainly in the thrombus and the intima. Among infiltrating cells, CD3(+) T cells greatly outnumbered CD20(+) B cells. CD68(+) macrophages or S-100(+) dendritic cells were detected, especially in the intima during acute and subacute stages. All cases except one showed infiltration by the human leukocyte antigen-D region (HLA-DR) antigen-bearing macrophages and dendritic cells in the intima. Immunoglobulins G, A, and M (IgG, IgA, IgM) and complement factors 3d and 4c (C3d, C4c) were deposited along the internal elastic lamina. CONCLUSION: Buerger's disease is strictly an endarteritis that is introduced by T-cell mediated cellular immunity and by B-cell mediated humoral immunity associated with activation of macrophages or dendritic cells in the intima. (+info)

The intrarenal vascular lesions associated with primary antiphospholipid syndrome. (8/5349)

Even 10 yr after the identification of the antiphospholipid syndrome (APS), renal involvement in the course of APS is still relatively unrecognized, and is probably underestimated. The association of anticardiolipin antibodies and/or lupus anticoagulant with the development of a vaso-occlusive process involving numerous organs is now confirmed. In a multicenter study, 16 cases of "primary" APS (PAPS) were found and followed for 5 yr or more, all with renal biopsy. In all 16 cases of PAPS, there was a vascular nephropathy characterized by small vessel vaso-occlusive lesions associated with fibrous intimal hyperplasia of interlobular arteries (12 patients), recanalizing thrombi in arteries and arterioles (six patients), and focal cortical atrophy (10 patients). In combination, these led to progressive destruction of the kidney, accelerated by acute glomerular and arteriolar microangiopathy in five patients. Focal cortical atrophy is a distinctive lesion, present in 10 biopsies, and likely represents the histologic and functional renal analogue to the multiple cerebral infarcts detected on imaging studies. The clinical hallmark of this vascular nephropathy in PAPS is systemic hypertension, only variably associated with renal insufficiency, proteinuria, or hematuria. The ensemble of histologic renal lesions defined in this study should aid in the separation of the lesions found in cases of secondary APS, especially systemic lupus erythematosus, into those lesions related to APS and those related to the underlying disease. (+info)

Thrombosis[edit]. CASS4 signaling may contribute to platelet activation and aggregation. A PKA/PKG phosphorylation site has ...

https://en.wikipedia.org/wiki/CASS4

Thrombosis[edit]. Complications involve portal vein thrombosis and splenic vein thrombosis: clotting of blood affects the ... thrombosis of the hepatic vein) and portal vein thrombosis. Additionally, the sonographer can make an estimation of the amount ... unless the thrombosis is very minor. In case of minor thrombosis, there are some chances of survival using cadaveric liver ... When a liver cirrhosis patient is suffering from thrombosis, it is not possible to perform a liver transplant, ...

https://en.wikipedia.org/wiki/Ascites

Deep vein thrombosis[edit]. Deep vein thrombosis (DVT) has an incidence of 0.5 to 7 per 1,000 pregnancies, and is the second ... with low molecular weight heparin may be indicated when there are additional risk factors for deep vein thrombosis.[16] ...

https://en.wikipedia.org/wiki/Complications_of_pregnancy

Cerebral venous sinus thrombosis, cavernous sinus thrombosis and jugular vein thrombosis: thrombosis of the veins of the brain ... A venous thrombosis is a thrombosis in a vein, caused by a thrombus (blood clot). A common type of venous thrombosis is a deep ... Budd-Chiari syndrome (thrombosis of the hepatic vein). *Thrombosis of the splanchnic venous system: *Mesenteric vein thrombosis ... Renal vein thrombosis (thrombosis of the veins of the kidneys. Parodoxical embolism[edit]. Systemic embolism of venous origin ...

https://en.wikipedia.org/wiki/Thromboembolism

Thrombosis is a term for a blood clot occurring inside a blood vessel. A common type of venous thrombosis is a deep vein ... Superficial venous thromboses cause discomfort but generally not serious consequences, as do the deep venous thromboses (DVTs) ... In contrast to the understanding for how arterial thromboses occur, as with heart attacks, venous thrombosis formation is not ... Portal vein thrombosis. References[edit]. *^ Saha P, Humphries J, Modarai B, et al. (2011). "Leukocytes and the natural history ...

https://en.wikipedia.org/wiki/Venous_thromboembolism

"Thrombosis. 2013: 640723. doi:10.1155/2013/640723. PMC 3885278. PMID 24455237.. *^ Sanders, Gillian D.; Lowenstern, Angela; ... "Cardiac imaging for assessment of left atrial appendage stasis and thrombosis". Nature Reviews. Cardiology. 11 (8): 470-80. doi ... Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; Council on Lifestyle and Cardiometabolic Health ... "Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College ...

https://en.wikipedia.org/wiki/Atrial_fibrillation

Thrombosis Research. 163: 117-122. doi:10.1016/j.thromres.2018.01.047. PMID 29407622.. ...

https://en.wikipedia.org/wiki/Activated_charcoal

Defects in protein Z lead to increased factor Xa activity and a propensity for thrombosis. ... Thrombosis, and Vascular Biology. 27 (6): 1238-47. doi:10.1161/ATVBAHA.107.139402. PMID 17379841.. ... this is desirable to prevent thrombosis. As of late 2007, four out of five emerging anti-coagulation therapeutics targeted this ...

https://en.wikipedia.org/wiki/Factor_X

People with high levels of factor VIII are at increased risk for deep vein thrombosis and pulmonary embolism. Copper is a ... Fang H, Wang L, Wang H (2007). "The protein structure and effect of factor VIII". Thrombosis Research. 119 (1): 1-13. doi: ... Lavigne-Lissalde G, Schved JF, Granier C, Villard S (October 2005). "Anti-factor VIII antibodies: a 2005 update". Thrombosis ... Antonarakis SE (July 1995). "Molecular genetics of coagulation factor VIII gene and hemophilia A". Thrombosis and Haemostasis. ...

https://en.wikipedia.org/wiki/Factor_VIII

Elice, F; Rodeghiero, F (2012). "Side effects of anti-angiogenic drugs". Thrombosis Research. 129 Suppl 1: 50-3. doi:10.1016/ ... Bruemmer, D. (2012). "Targeting Angiogenesis as Treatment for Obesity". Arteriosclerosis, Thrombosis, and Vascular Biology. 32 ...

https://en.wikipedia.org/wiki/Angiogenesis_inhibitor

Thrombosis Research. 110 (5-6): 255-8. doi:10.1016/S0049-3848(03)00379-7. PMID 14592543. Archived (PDF) from the original on 28 ... Gaciong Z (June 2003). "The real dimension of analgesic activity of aspirin". Thrombosis Research. 110 (5-6): 361-4. doi: ... Journal of Thrombosis and Haemostasis. 6 (10): 1832-4. doi:10.1111/j.1538-7836.2008.03122.x. PMID 18680540.. ...

https://en.wikipedia.org/wiki/Acetylsalicylic_acid

In older patients, there was an apparent increased incidence of breast cancer, heart attacks, venous thrombosis, and stroke, ... George, James L.; Colman, Robert W.; Goldhaber, Samuel Z.; Victor J. Marder (2006). Hemostasis and thrombosis: basic principles ... Olié, V. R.; Canonico, M.; Scarabin, P. Y. (2010). "Risk of venous thrombosis with oral versus transdermal estrogen therapy ...

https://en.wikipedia.org/wiki/Hormone_replacement_therapy

All three studies showed that the risk of new thrombosis was decreased with the use of lepirudin, but the risk for major ... Argatroban has been approved in the USA since 2000 for the treatment of thrombosis in patients with HIT and 2002 for ... Desirudin also reduced the rate of proximal deep vein thrombosis. Bleeding rates were similar with desirudin and heparin. ... doi:10.1016/S0266-4356(03)00242-0. Shapiro, Sandor S. (2003). "Treating Thrombosis in the 21st Century". New England Journal of ...

https://en.wikipedia.org/wiki/Discovery_and_development_of_direct_thrombin_inhibitors

Thrombosis research. 135 (2): 231-42. doi:10.1016/j.thromres.2014.11.012. PMID 25559460.. ...

https://en.wikipedia.org/wiki/Tranexamic_acid

... on thrombosis".[56] Another study reported that the species may be effective in stopping platelet binding in vitro,[57] with ... Thrombosis Research. 112 (3): 151-8. doi:10.1016/j.thromres.2003.10.022. PMID 14967412.. ...

https://en.wikipedia.org/wiki/Jew's_ear

"Postpartum deep vein thrombosis and pulmonary embolism in twin pregnancy: undertaking of clinical symptoms leading to massive ...

https://en.wikipedia.org/wiki/Postnatal

Venous thrombosis; certain arterial thrombotic conditions; patients with deep vein thrombosis, pulmonary embolism, cerebral ... deep vein thrombosis, thromboembolism, pregnancy associated with thrombosis/embolism, hyperhomocysteinemia, and multiple ... Individuals with the mutation are at increased risk of thrombosis in the setting of oral contraceptive use, trauma, and surgery ... Venous thrombosis; pulmonary embolism; transient ischemic attack or premature stroke; peripheral vascular disease, particularly ...

https://en.wikipedia.org/wiki/Gene_testing

"Journal of Thrombosis and Haemostasis. 9 Suppl 1 (Suppl 1): 306-15. doi:10.1111/j.1538-7836.2011.04318.x. PMC 3151023 . PMID ... Morrissey JH (May 2003). "Tissue factor: in at the start...and the finish?". Journal of Thrombosis and Haemostasis. 1 (5): 878- ... Furie B, Furie BC (2007). "Cancer-associated thrombosis". Blood Cells, Molecules & Diseases. 36 (2): 177-81. doi:10.1016/j.bcmd ... Golino P (May 2002). "The inhibitors of the tissue factor:factor VII pathway". Thrombosis Research. 106 (3): V257-65. doi: ...

https://en.wikipedia.org/wiki/Tissue_factor

... thrombosis, and vascular biology. 19 (3): 680-6. doi:10.1161/01.atv.19.3.680. PMID 10073973. Yoo, H; Kim, S. J.; Kim, Y; Lee, H ... Thrombosis, and Vascular Biology. 29 (6): 915-20. doi:10.1161/ATVBAHA.109.185793. PMID 19286633. Yokomizo, T; Kato, K; Hagiya, ... Thrombosis research. 63 (2): 239-48. doi:10.1016/0049-3848(91)90287-7. PMID 1837628. Siangjong, L; Gauthier, K. M.; Pfister, S ...

https://en.wikipedia.org/wiki/12-Hydroxyeicosatetraenoic_acid

Venous thrombosis /. Thrombophlebitis. *primarily lower limb *Deep vein thrombosis. *abdomen *Hepatic veno-occlusive disease ...

https://en.wikipedia.org/wiki/Intermittent_claudication

... thrombosis. These changes create an exaggerated layered appearance (onion skinning).[11] ...

https://en.wikipedia.org/wiki/Hypertensive_nephropathy

"Thrombosis and Haemostasis. 95 (1): 117-127. doi:10.1160/TH05-06-0413. ISSN 0340-6245.. ...

https://en.wikipedia.org/wiki/Endocannabinoid_transporter

Venous thrombosis /. Thrombophlebitis. *primarily lower limb *Deep vein thrombosis. *abdomen *Hepatic veno-occlusive disease ...

https://en.wikipedia.org/wiki/Hypertensive_emergency

"Thrombosis and Haemostasis. 101 (2): 271-78. doi:10.1160/th08-09-0575. PMID 19190809. Retrieved 19 June 2009.. ...

https://en.wikipedia.org/wiki/Secondary_hypertension

From various lines of evidence, it appears that thrombosis and embolism is the predominant problem.[1] ... irregularities in the vessel wall and turbulence increase the risk of thrombosis (the formation of blood clots) and embolism ( ...

https://en.wikipedia.org/wiki/Vertebral_artery_dissection

Venous thrombosis /. Thrombophlebitis. *primarily lower limb *Deep vein thrombosis. *abdomen *Hepatic veno-occlusive disease ...

https://en.wikipedia.org/wiki/Cerebral_aneurysm

This delivery system can cause sepsis and thrombosis. Prostacyclin is unstable, and therefore has to be kept on ice during ... The mechanisms involved in this narrowing process include vasoconstriction, thrombosis, and vascular remodeling (excessive ...

https://en.wikipedia.org/wiki/Pulmonary_Hypertension

Hepatic vein thrombosis: Oral contraceptives. Neoplasm[edit]. Neoplasms have been described with prolonged exposure to some ...

https://en.wikipedia.org/wiki/Hepatotoxicity

Renal vein thrombosis. *Trauma-including blunt trauma to the urinary tract or traumatic foley catheter placement[8] ...

https://en.wikipedia.org/wiki/Blood_in_the_urine

Venous thrombosis /. Thrombophlebitis. *primarily lower limb *Deep vein thrombosis. *abdomen *Hepatic veno-occlusive disease ...

https://en.wikipedia.org/wiki/Pituitary_apoplexy

Thrombosis may occur in veins (venous thrombosis) or in arteries (arterial thrombosis). Venous thrombosis leads to congestion ... Renal vein thrombosis[edit]. Main article: Renal vein thrombosis. Renal vein thrombosis is the obstruction of the renal vein by ... Deep vein thrombosis[edit]. Main article: Deep vein thrombosis. Deep vein thrombosis (DVT) is the formation of a blood clot ... Portal vein thrombosis[edit]. Main article: Portal vein thrombosis. Portal vein thrombosis affects the hepatic portal vein, ...

https://en.wikipedia.org/wiki/Thrombosis

Deep vein thrombosis (DVT) is a condition in which a blood clot develops in the deep veins, most commonly in the lower ... Deep Vein Thrombosis & Pulmonary Embolism. Nimia L. Reyes, Michele G. Beckman, Karon Abe ... The effect of flight-related behaviour on the risk of venous thrombosis after air travel. Br J Haematol. 2009 Feb;144(3):425-9. ... The American College of Chest Physicians published the 9th edition of their Antithrombotic Therapy and Prevention of Thrombosis ...

https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-by-air-land-sea/deep-vein-thrombosis-and-pulmonary-embolism

... and deep vein thrombosis (DVT) in people aged 16 and over ... Embolism and thrombosis Venous thromboembolism in over 16s: ... Take into account the risk of bleeding and of comorbidities such as arterial thrombosis. ... the signs and symptoms of deep vein thrombosis (DVT) and pulmonary embolism ... reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism NICE guideline [NG89]. Published date: 21 ...

https://www.nice.org.uk/guidance/ng89/chapter/Recommendations

Renal vein thrombosis[edit]. Main article: Renal vein thrombosis. Renal vein thrombosis is the obstruction of the renal vein by ... Deep vein thrombosis[edit]. Main article: Deep vein thrombosis. Deep vein thrombosis (DVT) is the formation of a blood clot ... Portal vein thrombosis[edit]. Main article: Portal vein thrombosis. Portal vein thrombosis affects the hepatic portal vein, ... Cavernous sinus thrombosis[edit]. Main article: Cavernous sinus thrombosis. Cavernous sinus thrombosis is a specialised form of ...

https://en.wikipedia.org/wiki/Vascular_thrombosis

Thrombosis. Br Med J 1973; 4 doi: https://doi.org/10.1136/bmj.4.5890.497-a (Published 24 November 1973) Cite this as: Br Med J ...

http://www.bmj.com/content/4/5890/497.2

Physiologic thrombosis is counterbalanced by intrinsic an... more ... Thrombosis is an important part of the normal hemostatic ... What is thrombosis?. Updated: Aug 04, 2021 * Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD ... Thrombosis is an important part of the normal hemostatic response that limits hemorrhage caused by microscopic or macroscopic ... Physiologic thrombosis is counterbalanced by intrinsic antithrombotic properties and fibrinolysis. Under normal conditions, a ...

https://www.medscape.com/answers/811234-88066/what-is-thrombosis

Travelers with an increased risk of deep vein thrombosis, a blood clot forming in a vein, should discuss this risk with their ... DEEP VEIN THROMBOSIS Travelers with an increased risk of deep vein thrombosis (DVT), a blood clot forming in a vein, should ...

https://www.cdc.gov/niosh/travel/pretravel/thrombosis.html

Stent thrombosis is a rare complication of percutaneous coronary intervention and carries a poor prognosis. Recent improvements ... Coronary stent thrombosis has been defined by the Academic Research Consortium criteria. Four types of thrombosis are defined ... Predictors of coronary stent thrombosis: the Dutch Stent Thrombosis Registry. J Am Coll Cardiol. 2009;53:1399-409.CrossRef ... Nakazawa G. Stent thrombosis of drug eluting stent: pathological perspective. J Cardiol. 2011;58:84-91.CrossRefPubMedGoogle ...

https://link.springer.com/chapter/10.1007%2F978-3-319-55994-0_59

3. Thrombosis Thrombosis  Clot in an inappropriate site --uninjured blood vessel  Clot in an inappropriate site uninjured ... Hemostasis and Thrombosis  Hemostasis and Thrombosis  Embolism  Embolism  Infarction  Infarction  Shock  Shock 1 Dr. ... 5. thrombosis; hemodynamic disorders * 1. Hemodynamic Disorders Hemodynamic Disorders  Edema  Edema  Hyperemia and ... 2. THROMBOSIS -Virchow triad 2 Dr. Krishna Tadepalli, MD, www.mletips.com ...

https://www.slideshare.net/krishnatadepalli/5-thrombosis-hemodynamic-disorders

Thrombosis, formation of a blood clot in the heart or in a blood vessel. Factors that play a role in the formation of clots ( ... blood disease: Thrombosis. Thrombosis, the formation of a blood clot (thrombus) that tends to plug functionally normal blood ... Thrombosis, formation of a blood clot in the heart or in a blood vessel. Factors that play a role in the formation of clots ( ... Effects of thrombosis may be blockage of the blood vessel at the point of clot formation or blockage of a vessel at some other ...

https://www.britannica.com/science/thrombosis

an arterial thrombosis is a blood clot in an artery. a clot from a deep vein usually doesnt move to the heart to cause a heart ... What is an arterial thrombosis?. ANSWER An arterial thrombosis is a blood clot in an artery. A clot from a deep vein usually ... CDC: "Deep Vein Thrombosis [DVT] / Pulmonary Embolism [PE] -- Blood Clot Forming in a Vein, Facts." ... CDC: "Deep Vein Thrombosis [DVT] / Pulmonary Embolism [PE] -- Blood Clot Forming in a Vein, Facts." ...

https://www.webmd.com/dvt/qa/what-is-an-arterial-thrombosis

Re: Deep vein thrombosis. Figure 1 which shows deep vein thrombosis in the right leg of a patient with leg swelling and ... Re: Deep vein thrombosis. Deep vein thrombosis (DVT) usually starts in the calf but by the time symptoms develop most patients ... Re: Deep vein thrombosis. With regards to the clinical update article Deep Venous Thrombosis by Stubbs et al BMJ 24/02/2018, ... Deep venous thrombosis and progestogens. Studds and colleagues list "Oestrogen therapy" as a cause of deep venous thrombosis ...

http://www.bmj.com/content/360/bmj.k351/rapid-responses

Source for information on Venous Thrombosis Prevention: The Gale Encyclopedia of Surgery and Medical Tests dictionary. ... Deep vein thrombosis (DVT) can be quite serious. DVT occurs when a blood clot (thrombus) forms in the legs or pelvis; in a few ... "Venous Thrombosis Prevention ." The Gale Encyclopedia of Surgery and Medical Tests. . Encyclopedia.com. (August 6, 2020). https ... Venous Thrombosis Prevention. Definition. Purpose. Description. Prevention methods. Preparation. Normal results. Definition. ...

https://www.encyclopedia.com/medicine/encyclopedias-almanacs-transcripts-and-maps/venous-thrombosis-prevention-0

The Journal of Thrombosis and Thrombolysis is a long-awaited resource for contemporary cardiologists, hematologists, vascular ... Journal of Thrombosis and Thrombolysis. A Journal for Translation, Application and Therapeutics in Thrombosis and Vascular ... The Journal of Thrombosis and Thrombolysis integrated format will expand the readers knowledge base and provide important ... The Journal of Thrombosis and Thrombolysis integrated format will expand the readers knowledge base and provide important ...

http://www.springer.com/medicine/cardiology/journal/11239?hideChart=1

Thrombosis is the formation of a mass of aggregated blood factors (a thrombus, or blood clot); coagulation of the blood. ... deep-vein thrombosis. Surviving a long-distance plane flight. Polycythaemia Rubra Vera. deep venous thrombosis. ... Thrombosis is the formation of a mass of aggregated blood factors (a thrombus, or blood clot); coagulation of the blood. ... splenic vein thrombosis. Instead of the single bullet theory. blood clot. Embolism. ...

https://everything2.com/title/thrombosis

Thrombosis is the process of a blood clot, also known as a thrombus, forming in a blood vessel. This clot can block or obstruct ... Thrombosis Types. Thrombosis can be broadly classified as either venous thrombosis or arterial thrombosis, according to where ... Venous thrombosis occurs in the veins and is categorized further according to where it occurs including:. *Deep vein thrombosis ... Cerebral venous sinus thrombosis. Arterial thrombosis, also known as atherothrombosis due to its association with atheroma ...

https://www.news-medical.net/health/What-is-Thrombosis.aspx

Factor V Leiden and Venous Thrombosis. alert icon Archived: This Page Is No Longer Being Updated This web page is archived ... Factor V Leiden (FVL) and oral contraceptive (OC) use among women with venous thrombosis and controls* FVL†. Cases +. Controls ... Factor V Leiden (FVL) and oral contraceptive (OC) use among women with venous thrombosis and controls*. +. +. 25 ... Association between factor V Leiden (FVL) and oral contraceptive (OC) use in women with venous thrombosis. FVL*. +. 25 ...

https://www.cdc.gov/genomics/hugenet/casestudy/fvl/fvlcase.htm

Health Information on Deep Vein Thrombosis: MedlinePlus Multiple Languages Collection ... Deep Vein Thrombosis: MedlinePlus Health Topic - English Trombosis venosa profunda: Tema de salud de MedlinePlus - español ( ...

https://medlineplus.gov/languages/deepveinthrombosis.html

Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney. ... Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney. ... In most cases, there is no specific way to prevent renal vein thrombosis. Keeping enough fluids in the body may help reduce ... Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. Blood thinners such as ...

https://medlineplus.gov/ency/article/000513.htm

D-dimer assays are used as a tool to rule out thrombosis in symptomatic patients with lupus, but could they also be used to ... Of the 15 patients who had evidence of thrombosis, 14 had D-dimer levels greater than 2.0 µg/ml (,0.5 µg/ml being considered a ... This Practice Point commentary considers whether the D-dimer assay will remain simply a tool to rule out thrombosis in ... Patients with nephrotic syndrome are at increased risk of thrombosis, and previous risk-benefit assessments support the use of ...

https://www.medscape.com/viewarticle/585634_1

To determine factors associated with early pancreatic allograft thrombosis (EPAT). Thrombosis is the leading non-immunological ... Early pancreas allograft thrombosis.. Ramessur Chandran S1, Kanellis J, Polkinghorne KR, Saunder AC, Mulley WR. ...

https://www.ncbi.nlm.nih.gov/pubmed/23495654?dopt=Abstract

Journal of Thrombosis and Thrombolysis A Journal for Translation, Application and Therapeutics in Thrombosis and Vascular ... New Drugs and Technology in Thrombosis and Hemostasis. Vance G. Nielsen, MD, University of Arizona, Tucson, Arizona, USA ... Artificial Intelligence and Machine Learning in Thrombosis, Hemostasis and Vascular Biology. Pharmacology and Practical ... Paul Gurbel, MD, Inova Center for Thrombosis Research and Translational Medicine, Lutherville, MD (USA) ...

https://www.springer.com/journal/11239/editors

Jeff Burzynski raises an interesting point about the danger of the hyperosmolar state and risk of thrombosis. In the patient ... Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis. Crit Care Med 2003;31 ... Worly JM, Fortenberry JD, Hansen I, Chambliss CR, Stockwell J. Deep venous thrombosis in children with diabetic ketoacidosis ... described in a 2-week-old breast-feeding baby who experienced transverse sinus thrombosis4 was much more severe than what was ...

https://www.cmaj.ca/content/173/2/132.2

Raise free funds for Thrombosis UK today by shopping online via Easyfundraising. Click now to shop at no extra cost and raise ... Thrombosis UK is dedicated to promoting the awareness, research and care of thrombosis. ... Raise donations for Thrombosis UK whenever you shop online. Turn your everyday online shopping into FREE donations ...

https://www.easyfundraising.org.uk/causes/thrombosisuk/

Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis. Crit Care Med 2003;31 ... Worly JM, Fortenberry JD, Hansen I, Chambliss CR, Stockwell J. Deep venous thrombosis in children with diabetic ketoacidosis ... 2 The mostly adult entity of hyperosmolar nonketotic coma has had various degrees of association with thrombosis,2,3 as has ... there is a higher incidence of deep venous thrombosis with femoral central venous lines.5,6 Serum glucose and sodium ...

https://www.cmaj.ca/content/173/2/132.1

Working Group on Thrombosis in Pediatric Cardiology and Congenital Heart Disease Brian W. McCrindle, Jennifer S. Li, Cedric ... Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by ...

http://circ.ahajournals.org/collection/thrombosis?page=6

Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...

http://circ.ahajournals.org/content/40/6/755

Learn about the types of thrombosis conditions, where in the human body they happen, the various symptoms of each type, and ... Thrombosis is the medical term for a clot inside a blood vessel. ... Femoral Vein Thrombosis. This is a clot in the long vein in ... Stroke: "Diagnosis and Management of Cerebral Venous Thrombosis.". Johns Hopkins Medicine: "Cerebral Venous Sinus Thrombosis ( ... American College of Cardiology: "Upper Extremity Deep Vein Thrombosis.". Medscape: "Internal Jugular Vein Thrombosis," " ...

https://www.webmd.com/dvt/ss/slideshow-thrombosis-types

deep venous thrombosis. November 27, 2010. Adventures in the emergency room. Angel Problem. Instead of the single bullet theory ... deep-vein thrombosis. Surviving a long-distance plane flight. anti-embolism stocking. A farewell to stockings. ...

https://everything2.com/title/deep+vein+thrombosis

A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. ...

https://www.mayoclinic.org/diseases-conditions/deep-vein-thrombosis/multimedia/deep-vein-thrombosis-video/vid-20112355

CDC: "Deep Vein Thrombosis [DVT] / Pulmonary Embolism [PE] -- Blood Clot Forming in a Vein, Facts. (webmd.com)
exhibited signs or symptoms of incident thromboembolic events including pulmonary embolism, arterial thrombosis, unexplained hypoxic lung injury, microangiopathic antiphospholipid syndrome, Libman-Sacks endocarditis-related embolism, and thrombotic microangiopathic hemolytic anemia. (medscape.com)
People who are cooped up during extended periods of travel are at risk for a condition called deep vein thrombosis (DVT) and pulmonary embolism. (newsmax.com)
Each year 400,000 Americans develop deep-vein thrombosis (DVT), with approximately half of those cases resulting in a blood clot called a pulmonary embolism (PE), a potentially fatal condition. (sheknows.com)
A deep vein thrombosis can break loose and cause a serious problem in the lung, called a pulmonary embolism, or a heart attack or stroke. (news-medical.net)
The most serious complication of deep vein thrombosis is pulmonary embolism , in which a blood clot breaks off of the DVT and travels through the bloodstream and becomes lodged in a blood vessel of the lung. (medicinenet.com)
Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. (medscape.com)
Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. (medscape.com)
Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. (medscape.com)
A deep vein thrombosis - a clot, usually in a lower leg - is one major cause of pulmonary embolism. (medicalnewstoday.com)
Venous thromboembolism or VTE is a condition in which blood clots form most often in the deep veins of the leg, known as deep vein thrombosis or DVT, and can travel in the circulation and lodge in the lungs, known as pulmonary embolism or PE. (punchng.com)
If you or a loved one has been diagnosed with a thrombotic disease, such as deep vein thrombosis (DVT), pulmonary embolism (PE) or other vascular disorder, Park Nicollet offers the expert care to evaluate and treat your condition. (parknicollet.com)
Herein we report a 57-year-old man with HES who presented with deep venous thrombosis of the lower extremities, portal thrombosis, pulmonary embolism, and mesenteric venous thrombosis , which led to intestinal obstruction. (thefreedictionary.com)
Their topics include cilostazol and dipyridamole: much more than weak inhibition of platelets, unfractionated heparin and low molecular weight heparin in ischemic heart disease, vitamin K antagonists, anti-thrombotic strategies in patients undergoing elective percutaneous coronary interventions, and anti-thrombotic therapy in venous thrombosis and pulmonary embolism. (thefreedictionary.com)
Several studies have assessed the risk of venous thrombosis (a collective term for deep vein thrombosis and pulmonary embolism) in women using oral contraceptive pills, but few studies have assessed the risk in users of non-oral hormonal contraceptives. (thefreedictionary.com)
The outcome measures of the retrospective cohort analysis were thromboembolic events, including deep vein thrombosis, myocardial infarction, ischemic stroke, and pulmonary embolism. (medpagetoday.com)
The term venous thromboembolism (VTE) is used to describe two conditions, deep vein thrombosis (DVT) and pulmonary embolism (PE) . (hopkinsmedicine.org)
The drug is already approved for prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, for prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing hip or knee replacement surgery, and for treatment of DVT or PE and reduction in the risk of recurrence of DVT or PE. (medpagetoday.com)
We also provide comprehensive care to children, adolescents and adults with complex inherited or acquired thrombotic disorders, including deep venous thrombosis, pulmonary embolism and thrombotic thrombocytopenia purpura. (massgeneral.org)
Deep Vein Thrombosis - I had a blood clot in my popliteal vein and a pulmonary embolism? (drugs.com)
The abbreviation DVT/PE refers to a VTE where a deep vein thrombosis (DVT) has moved to the lungs (PE or pulmonary embolism). (wikipedia.org)

Thrombosis may occur in veins ( venous thrombosis ) or in arteries ( arterial thrombosis ). (wikipedia.org)
Venous thrombosis leads to congestion of the affected part of the body, while arterial thrombosis (and rarely severe venous thrombosis) affects the blood supply and leads to damage of the tissue supplied by that artery ( ischemia and necrosis ). (wikipedia.org)
Thrombosis is generally defined by the type of blood vessel affected (arterial or venous thrombosis) and the precise location of the blood vessel or the organ supplied by it. (wikipedia.org)
What is an arterial thrombosis? (webmd.com)
An arterial thrombosis is a blood clot in an artery. (webmd.com)
But an arterial thrombosis can. (webmd.com)
Thrombosis can be broadly classified as either venous thrombosis or arterial thrombosis, according to where the thrombus presents in the body. (news-medical.net)
Arterial thrombosis, also known as atherothrombosis due to its association with atheroma rupture, occurs in the arteries. (news-medical.net)
Arterial thrombosis is when the blood clot blocks an artery. (uhhospitals.org)
Arterial thrombosis may be caused by a hardening of the arteries (atherosclerosis). (uhhospitals.org)
Arterial thrombosis can occur in the arteries that supply blood to the heart muscle (coronary arteries). (uhhospitals.org)
When arterial thrombosis occurs in a blood vessel in the brain, it can lead to a stroke. (uhhospitals.org)
Many of the risk factors for venous and arterial thrombosis are the same. (uhhospitals.org)
So far, the evidence for a role of the fibrinolytic system in the defence against arterial thrombosis stems from observations on different patient-groups, and this evidence is steadily becoming stronger. (springer.com)
Stormorken H. (1984) Fibrinolytic Vessel Wall Activator in Arterial Thrombosis. (springer.com)
The vessel may be any vein or artery as for example, in a deep vein thrombosis (venous) or a coronary artery (arterial). (punchng.com)
The two broad classifications of thrombosis are venous and arterial, depending on whether the clot develops in the vein or an artery. (punchng.com)
1) The third type of HIT is associated with clinically significant arterial and/or venous thrombosis (HITT) with consequent high morbidity and mortality. (thefreedictionary.com)
The two types of thrombosis are arterial thrombosis and venous thrombosis. (wisegeek.com)
Most cases of arterial thrombosis result from the rupture of an atheroma, a lesion of accumulated lipids, macrophages, and connective tissue on the walls of blood vessels, characteristic of atherosclerosis. (wisegeek.com)
citation needed] Arterial thrombosis is the formation of a thrombus within an artery. (wikipedia.org)
In most cases, arterial thrombosis follows rupture of atheroma (a fat-rich deposit in the blood vessel wall), and is therefore referred to as atherothrombosis. (wikipedia.org)

As of June 2018, current guidelines from the American College of Chest Physicians (ACCP) and the National Comprehensive Cancer Network (NCCN) recommend LMWH for the first 3-6 months of treatment for cancer-associated thrombosis, and long-term anticoagulation for as long as malignancy is present. (washington.edu)
Ongoing clinical trials comparing LMWH to DOAC therapy for intial treatment of cancer-associated thrombosis may alter these guidelines in the future. (washington.edu)
For a start, the multi-professional healthcare workers in the oncology and thrombosis worlds, need to talk together regularly to coordinate a cancer-associated-thrombosis (CAT) patient care pathway. (warwick.ac.uk)

Deep vein thrombosis (DVT) is a condition in which a blood clot develops in the deep veins, most commonly in the lower extremities. (cdc.gov)
Venous thrombosis prevention refers to the use of medications, other devices, or behavioral changes to prevent blood clots from forming in veins within the body. (encyclopedia.com)
Venous thrombosis consists of blood clots forming abnormally in the leg veins (deep vein thrombosis or DVT) or the lung arteries (pulmonary embolus or PE). (burlingtonfreepress.com)
Thrombosis can block the blood flow in both veins and arteries. (uhhospitals.org)
Thrombosis occurs when blood clots block veins or arteries. (uhhospitals.org)
Symptoms of deep vein thrombosis ( DVT ) occur when there is a blood clot in one of the deep veins (vessels that return blood to the heart after it has delivered oxygen to the tissues). (medicinenet.com)
Hepatic vein thrombosis (HVT) is an obstruction in the hepatic veins of the liver caused by a blood clot. (healthline.com)
Thrombosis of the cerebral veins and sinuses. (nih.gov)
Deep vein thrombosis, or DVT, is a medical condition in which blood clots (thrombi) form in deep veins, usually of the calf, thigh or pelvis. (wikihow.com)
Thrombosis in the Veins of Petroleum. (ebscohost.com)
Cerebral thrombosis most often refers to thrombus formation within cerebral arteries, and the cerebral venous thrombosis refers to clot formation within cerebral veins and sinuses. (wisegeek.com)
Penile thrombosis is the formation of a painful blood clot inside one of the veins in the penis. (wisegeek.com)
Thrombosis occurs when clots obstruct veins (blood vessels that carry blood from the body back into the heart) or arteries (blood vessels that carry oxygenated blood away from the heart to the body). (massgeneral.org)
Deep vein thrombosis" are clots in the deep veins. (health-alliance.com)
A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. (wikipedia.org)
Superficial venous thromboses cause discomfort but generally not serious consequences, as do the deep vein thromboses (DVTs) that form in the deep veins of the legs or in the pelvic veins. (wikipedia.org)
citation needed] While venous thrombosis of the legs is the most common form, venous thrombosis may occur in other veins. (wikipedia.org)

Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting") is the formation of a blood clot inside a blood vessel , obstructing the flow of blood through the circulatory system . (wikipedia.org)
Deep vein thrombosis (DVT) is the formation of a blood clot within a deep vein . (wikipedia.org)
Travelers with an increased risk of deep vein thrombosis (DVT), a blood clot forming in a vein, should discuss this risk with their healthcare provider and take action to decrease the risk. (cdc.gov)
3. Thrombosis Thrombosis  Clot in an inappropriate site --uninjured blood vessel  Clot in an inappropriate site uninjured blood vessel  DIC (Disseminated Intravascular coagulation)- multiple fibrin  DIC (Disseminated Intravascular coagulation)- multiple fibrin thrombi thrombi  Pathogenesis = Virchow's triad  Pathogenesis = Virchow's triad  1. (slideshare.net)
Thrombosis , formation of a blood clot in the heart or in a blood vessel . (britannica.com)
Effects of thrombosis may be blockage of the blood vessel at the point of clot formation or blockage of a vessel at some other point by a clot that has broken free from its point of origin. (britannica.com)
Thrombosis is the process of a blood clot, also known as a thrombus, forming in a blood vessel. (news-medical.net)
Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney. (medlineplus.gov)
Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body. (news-medical.net)
Natural News) A study published in The New England Journal of Medicine revealed that not all patients with deep vein thrombosis (DVT) require clot-clearing drugs and devices as the treatments did not reduce the risk of developing post-thrombotic syndrome, a condition characterized by chronic limb pain and swelling. (naturalnews.com)
Venous thrombosis is when the blood clot blocks a vein. (uhhospitals.org)
Conditions in which the blood is more likely than normal to clot (hypercoagulability) also increase the chance of deep vein thrombosis . (medicinenet.com)
Deep vein thrombosis (DVT) is a medical condition that happens when a blood clot forms in a vein. (healthline.com)
A superficial venous thrombosis is a blood clot in a vein that is close to the surface of the skin. (healthlinkbc.ca)
The most common type of blood clot in pregnancy is deep vein thrombosis (DVT), (Meng et al 2015, RCOG 2015a) which is a clot in a vein deep below your skin's surface. (babycentre.co.uk)
Deep vein thrombosis is a blood clot that forms inside a vein, usually deep within your leg. (rxlist.com)
Deep vein thrombosis is a blood clot or thrombus in a deep vein. (hopkinsmedicine.org)
A blood clot (thrombus) in the deep venous system of the leg leads to deep vein thrombosis (DVT). (medindia.net)
A cerebral thrombosis is a blood clot that forms within one of the cerebral vessels, diminishing the blood, oxygen , and nutrient supplies to the brain parenchyma. (wisegeek.com)
Deep Vein Thrombosis (DVT) occurs when a blood clot forms in a vein, frequently in the leg. (johnmuirhealth.com)
A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. (redorbit.com)
If we could find a way to dial back the enzyme's clot-forming effects, we might be able to offer new hope to patients suffering from clotting disorders and deep-vein thrombosis. (redorbit.com)
Venous thrombosis is thrombosis in a vein, caused by a thrombus (blood clot). (wikipedia.org)

Along with over 160 other organizations, Fletcher Allen Health Care is a partner in "World Thrombosis Day" on Monday. (burlingtonfreepress.com)
World Thrombosis Day 2020 was marked on October 13 all over the world. (punchng.com)
The World Thrombosis Day campaign aims to educate patients, caregivers and medical professionals about the early warning signs, the importance of screening upon hospital admission, prompt interventions and the optimal treatments. (punchng.com)
Today (13 Oct) is World Thrombosis Day . (warwick.ac.uk)

Healthline - What's the Difference Between Thrombosis and Embolism? (britannica.com)

Portal vein thrombosis affects the hepatic portal vein , which can lead to portal hypertension and reduction of the blood supply to the liver. (wikipedia.org)
The author reports a case of melioidosis with a rare manifestation of portal vein thrombosis and cavernous transformation of the portal vein. (hindawi.com)
moreover, portal vein thrombosis can be a potential complication. (hindawi.com)
His CT study showed multiple small liver abscesses, left portal vein thrombosis, and cavernous transformation of the portal vein (Figures 1 and 2 ). (hindawi.com)
Transient hepatic attenuation differences (THAD) due to left portal vein thrombosis were well visualized. (hindawi.com)
Left portal vein thrombosis caused transient hepatic attenuation differences (THAD) between the left and right lobes of the liver. (hindawi.com)

Stent thrombosis is a rare complication of percutaneous coronary intervention and carries a poor prognosis. (springer.com)
A common complication of thrombosis is hypoxia, due to the obstruction of the artery of vein. (news-medical.net)
conducted a case-control study to examine whether FVL might be a causative factor in venous thrombosis occurring as an uncommon but serious complication of oral contraceptive (OC) use. (cdc.gov)
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of death worldwide, making it a major health-care challenge. (nature.com)
Thrombosis is a known complication among COVID-19 patients. (punchng.com)
Penile thrombosis may also occur as a complication of a surgical procedure. (wisegeek.com)

Coronary angiography is limited to determination of the causes of thrombosis. (springer.com)
There are three main causes of thrombosis: hypercoagulability, injury to the endothelial cells of the blood vessel wall and abnormal flow of the blood. (news-medical.net)
Presents the interview with Beverly Hunt, consultant hematologist and founder member of the thrombosis charity Lifeblood, about risks and causes of thrombosis. (ebscohost.com)

Renal vein thrombosis is the obstruction of the renal vein by a thrombus. (wikipedia.org)
Jugular vein thrombosis is a condition that may occur due to infection, intravenous drug use or malignancy. (wikipedia.org)
NIH MedlinePlus: "Deep Vein Thrombosis: Symptoms, Diagnosis, Treatment and Latest NIH Research. (webmd.com)
National Heart, Lung, and Blood Institute: "How Is Deep Vein Thrombosis Treated? (webmd.com)
What activities can I do if I have deep vein thrombosis (DVT)? (webmd.com)
What are the lasting effects after deep vein thrombosis (DVT)? (webmd.com)
2 D'Angelo A, D'Alessandro G, Tomassini L, Pittet JL, Dupuy G, Crippa L. Evaluation of a new rapid quantitative D-dimer assay in patients with clinically suspected deep vein thrombosis.Thromb Haemost. (bmj.com)
Deep vein thrombosis (DVT) can be quite serious. (encyclopedia.com)
A more coherent method to prevent the formation of deep vein thrombosis is the use of compression stockings, which mechanically support the vein to inhibit the formation of blood clots. (news-medical.net)
Renal vein thrombosis is an uncommon disorder. (medlineplus.gov)
However, it may indicate nephrotic syndrome or other causes of renal vein thrombosis. (medlineplus.gov)
Renal vein thrombosis most often gets better over time without lasting damage to the kidneys. (medlineplus.gov)
Call your health care provider if you have symptoms of renal vein thrombosis. (medlineplus.gov)
In most cases, there is no specific way to prevent renal vein thrombosis. (medlineplus.gov)
Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. (medlineplus.gov)
Deep vein thrombosis has been associated with long-haul air travel, but people who work or play for excessive periods at their PCs are also at risk of developing blood clots that could lead to DVT, according to a new report. (zdnet.com)
Cancer, surgery, or using IV drugs can also cause jugular vein thrombosis. (webmd.com)
Radiometer Limited's AQT90 FLEX analyzers have been used in a successful trial to asses D-dimer point-of-care testing for suspected lower limb deep vein thrombosis (DVT). (news-medical.net)
People with deep-vein thrombosis can substantially cut their risk of potentially debilitating complications by starting adequate compression therapy in the first twenty-four hours of DVT therapy (known as the acute phase of treatment), suggests a study published today in the journal Blood. (news-medical.net)
We need to talk about deep vein thrombosis (DVT). (news.com.au)
The fit and healthy pilot suffered deep vein thrombosis, which was left untreated for two months. (news.com.au)
Acting Surgeon General Steven Galson issued a ' call to action ' this week to make more Americans aware of deep-vein thrombosis, life-threatening blood clots that occur in the legs or pelvis. (scientificamerican.com)
Most commonly, deep vein thrombosis occurs in a vein of the leg, but it can also occur in other locations such as the pelvis. (medicinenet.com)
Deep-vein thrombosis (DVT)��affects approximately 2 million Americans each year, according to the Coalition to Prevent Deep-Vein Thrombosis . (foxnews.com)
Deep vein thrombosis of lower extremity: direct intraclot injection of alteplase once daily with systemic anticoagulation--results of pilot study. (medscape.com)
What is hepatic vein thrombosis? (healthline.com)
The following may be signs and symptoms of a deep vein thrombosis. (medicalnewstoday.com)
The ornamental design for a compression sleeves for deep vein thrombosis, as shown and described. (google.com)
Jobst article entitled, Deep Vein Thrombosis, Form 294 R3 (1981). (google.com)
Massachusetts General Hospital is hosting an educational event to promote public awareness of deep-vein thrombosis. (massgeneral.org)
March is Deep-Vein Thrombosis (DVT) Awareness month. (massgeneral.org)
Am I at risk of deep vein thrombosis? (netdoctor.co.uk)
Are there any precautions I should take for deep vein thrombosis? (netdoctor.co.uk)
This is minor surgery so you shouldn't be at any extra significant risk of deep vein thrombosis (DVT) with the timescale involved. (netdoctor.co.uk)
What are the risk factors for deep vein thrombosis? (hopkinsmedicine.org)
Deep vein thrombosis may happen without symptoms. (hopkinsmedicine.org)
How is deep vein thrombosis diagnosed? (hopkinsmedicine.org)
How can deep vein thrombosis be prevented? (hopkinsmedicine.org)
Presents information on deep vein thrombosis. (ebscohost.com)
Possible complications from deep vein thrombosis. (ebscohost.com)
Examines on the cases of hepatic vein thrombosis. (ebscohost.com)
Association of hepatic vein thrombosis with myeloproliferative disorder in patients. (ebscohost.com)
International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) reported obstetric CVT in only 20% of cases as compared to reports from Mexico and India, which report a much higher frequency. (ahajournals.org)
Wang added that patients prone to deep-vein thrombosis might benefit from drugs that target the PAD4 enzyme. (redorbit.com)
Since then, we've learned about the dangers of another "silent killer" you might not be familiar with: Deep vein thrombosis (DVT). (cbsnews.com)
Once things settled down, we learned about the dangers of DVT, or deep vein thrombosis. (cbsnews.com)
The spate of recent deaths on long haul flights mostly due to caused by deep vein thrombosis has prompted the city's medical fraternity to deliberate on ways to tackle the problem. (hindustantimes.com)
Crew on board should be extensively trained to detect deep vein thrombosis. (hindustantimes.com)
Join the ' Deep Vein Thrombosis - First Event ' group to help and get support from people like you. (drugs.com)
Our support group for Deep Vein Thrombosis - First Event has 17 questions and 41 members. (drugs.com)
Deep Vein Thrombosis - First Event - Leg/ankle is really bothering me, is it DVT? (drugs.com)
There are 33 doctors for Deep Vein Thrombosis in Franklin . (healthgrades.com)
CNN reports that neither dehydration, drinking alcoholic beverages, nor sitting in economy class will increase the risk of DVT (Deep Vein Thrombosis). (smartertravel.com)
citation needed] Renal vein thrombosis is the obstruction of the renal vein by a thrombus. (wikipedia.org)
Venous thromboembolism and superficial vein thrombosis account for about 90% of venous thrombosis. (wikipedia.org)
Other rarer forms include retinal vein thrombosis, splanchnic vein thrombosis, cerebral venous sinus thrombosis, renal vein thrombosis, and ovarian vein thrombosis. (wikipedia.org)
Compared with combined oral contraceptives containing levonorgestrel (LNG), and with the same dose of estrogen and duration of use, the rate ratio of deep vein thrombosis for combined oral contraceptives with norethisterone is 0.98, with norgestimate 1.19, with desogestrel (DSG) 1.82, with gestodene 1.86, with drospirenone (DRSP) 1.64, and with cyproterone acetate 1.88. (wikipedia.org)

Recent improvements in stent technology and new antiplatelet therapies have reduced the incidence of stent thrombosis. (springer.com)
Coronary stent thrombosis has been defined by the Academic Research Consortium criteria. (springer.com)
By employing OCT, a number of pathologies such as malapposition, rupture of neoatherosclerosis, uncovered struts, restenosis, evagination, underexpansion, and dissection of the borders have been identified as risk factors for coronary stent thrombosis, allowing causal and specific treatments. (springer.com)
Predictors of coronary stent thrombosis: the Dutch Stent Thrombosis Registry. (springer.com)
Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials. (springer.com)
Stent thrombosis in drug-eluting or bare-metal stents in patients receiving dual antiplatelet therapy. (springer.com)
Kang S-H, Chae I-H, Park J-J, Lee HS, Kang D-Y, Hwang S-S, Youn T-J, Kim H-S. Stent thrombosis with drug-eluting stents and bioresorbable scaffolds: evidence from a network meta-analysis of 147 trials. (springer.com)
Drug-eluting stent thrombosis. (biomedsearch.com)
Additionally, concern exists regarding the long-term safety of DES, as there appears to be a small but real increase in late (LST) and very late stent thrombosis (VLST), seen particularly after the discontinuation of antiplatelet therapy. (biomedsearch.com)
SILVER SPRING, Md. -- The FDA has rejected an application for a new indication allowing rivaroxaban (Xarelto) to be used to reduce the risk of stent thrombosis in patients with acute coronary syndrome (ACS). (medpagetoday.com)

Discusses the mechanism and possible prevention of coronary thrombosis. (ebscohost.com)
Prevention of coronary thrombosis with linolenic acid. (ebscohost.com)

Cerebral venous sinus thrombosis (CVST) is a rare form of stroke which results from the blockage of the dural venous sinuses by a thrombus. (wikipedia.org)

We are pleased to partner with the Oregon Hemophilia and Thrombosis Center to provide a full range of factor medications at the lowest prices available in Oregon. (ohsu.edu)
The Hemophilia and Thrombosis Center at the University of Colorado Denver (UCHTC) is the region's leader for the treatment of patients with bleeding and clotting disorders, as well as an international leader in research for new treatments for these disorders. (idealist.org)
The Hemophilia and Thrombosis Center at MassGeneral Hospital for Children offers comprehensive evaluations and individualized care to children and adults with bleeding disorders due to hemophilia A, hemophilia B, rare clotting factor deficiencies and von Willebrand disease. (massgeneral.org)

Anticoagulants may increase the risk of major bleeding slightly, but has been found to offer a benefit in both the prevention and treatment of thrombosis. (news-medical.net)
The meeting goals integrated the DBDR mission to enhance health by promoting the prevention and treatment of thrombosis with the CSSI mission to employ trans-disciplinary approaches to enable progress in cancer research. (nih.gov)

The Journal of Thrombosis and Thrombolysis is a long-awaited resource for contemporary cardiologists, hematologists, vascular medicine specialists and clinician-scientists actively involved in treatment decisions and clinical investigation of thrombotic disorders involving the cardiovascular and cerebrovascular systems. (springer.com)
The Journal of Thrombosis and Thrombolysis ' integrated format will expand the reader's knowledge base and provide important insights for both the investigation and direct clinical application of the most rapidly growing fields in medicine-thrombosis and vascular science. (springer.com)

Venous thrombosis in the setting of malignancy is a well-known phenomenon explained by multiple factors that lead to a hypercoagulable state. (thefreedictionary.com)
Prevention of Thrombosis in Gynecologic Malignancy. (ebscohost.com)
Provides information on the prevention of thrombosis in gynecologic malignancy. (ebscohost.com)
Alongside patients and other European thrombosis and malignancy experts, this team are lobbying MEPs at the EU in Brussels today, to raise awareness of CAT, the challenge of preventing CAT and most importantly, our plan for improving the lives of people living with CAT. (warwick.ac.uk)

Thrombosis is an important part of the normal hemostatic response that limits hemorrhage caused by microscopic or macroscopic vascular injury. (medscape.com)

What are possible complications of thrombosis? (uhhospitals.org)
Complications depend on where the thrombosis is located. (uhhospitals.org)
Complications of thrombosis can be life-threatening, such as a stroke or heart attack. (uhhospitals.org)
At the Pauline Allen Gill Center for Cancer and Blood Disorders, we work hard to diagnose bleeding disorders and thrombosis early, using genetic screening and counseling when appropriate, and helping to prevent possible problems or complications in our young patients who are at risk. (childrens.com)
Your child's doctor will recommend treatment for thrombosis based on risk for complications. (childrens.com)
If they prevent thrombosis or pregnancy complications in the mouse models, clinical trials would of course follow," Dr. Shaul said. (medindia.net)

Thrombosis occurs when blood clots block your blood vessels. (uhhospitals.org)

Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. (bmj.com)
With regards to the clinical update article 'Deep Venous Thrombosis' by Stubbs et al BMJ 24/02/2018, I should like to highlight an important limitation of D-dimer testing in this context is its relatively short half life. (bmj.com)
The principal focus of the Journal centers on the pathobiology of thrombosis and vascular disorders and the use of anticoagulants, platelet antagonists, cell-based therapies and interventions in scientific investigation, clinical-translational research and patient care. (springer.com)
The Journal will publish original work which emphasizes the interface between fundamental scientific principles and clinical investigation, stimulating an interdisciplinary and scholarly dialogue in thrombosis and vascular science. (springer.com)
Wu and colleagues hypothesized that elevated levels of D-dimer would predate and, therefore, predict clinical manifestations of thrombosis. (medscape.com)
Cross-sectional imaging for diagnosis and clinical outcome prediction of acute basilar artery thrombosis. (medscape.com)
An evaluation of clinical signs in the diagnosis of venous thrombosis. (medscape.com)
Thrombosis Research is an international journal with a goal of rapid dissemination of new information on thrombosis , hemostasis , and vascular biology to advance science and clinical care. (elsevier.com)
Antithrombotic therapy for venous thromboembolic disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th Edition: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. (washington.edu)
Inflammatory conditions such as infection, chronic autoimmune diseases and clonal haematopoiesis of indeterminate potential are associated with an increased risk of thrombotic events, providing clinical evidence for the partnership between inflammation and thrombosis. (nature.com)
This review focuses on DES thrombosis, with particular attention paid to the definitions, incidence, mechanisms and clinical implications. (biomedsearch.com)
Cerebral venous thrombosis (CVT) is an uncommon cause of stroke with extremely diverse clinical features, predisposing factors, brain imaging findings, and outcome. (ahajournals.org)

Elevated levels of soluble fibrin or D-dimer indicate high risk of thrombosis.J Thromb Haemost.2006;4:1253-8. (bmj.com)
As part of this programme, we are highlighting a group of people at high risk of thrombosis - people living with cancer. (warwick.ac.uk)

As one of 130 centers in the national network of centers, Children's provides services to children with bleeding disorders and thrombosis diseases according to guidelines that are developed and established by the National Hemophilia Foundation (NHF), Maternal and Child health Bureau (MCBH), and the Centers for Disease Control and Prevention (CSC). (nationwidechildrens.org)
The Bleeding Disorders and Thrombosis Program at Children's Health is one of only five comprehensive treatment programs for hemophilia and other bleeding disorders in Texas. (childrens.com)
The Bleeding Disorders and Thrombosis program does extensive outreach beyond our clinic walls to provide better access and resources for our patients. (childrens.com)

By interacting with fibrin and platelet β3 integrin, pFn plays a self-limiting regulatory role in thrombosis, suggesting pFn transfusion may be a potential therapy for bleeding disorders, particularly in association with anticoagulant therapy. (jci.org)
Another possible for thrombosis is that treatment for ITP may cause the platelet count to rise too rapidly, he said. (medpagetoday.com)
Physicians should be aware of the risk of thrombosis and take care not to let the platelet count rise too high, Dr. Kuter said. (medpagetoday.com)
RBCs may contribute to hemostasis and thrombosis via mechanisms that include platelet margination leading to an increase in the near-wall platelet concentration, blood viscosity, thrombin generation, and platelet activation. (jci.org)

4 Recent evidence has also demonstrated that among children with DKA, there is a higher incidence of deep venous thrombosis with femoral central venous lines. (cmaj.ca)
The incidence of DES thrombosis is debated and varies somewhat by definition. (biomedsearch.com)

Overview of thrombosis and problems associated with abnormal blood clotting. (britannica.com)
The blood stasis caused by atrial fibrillation may also cause this type of thrombosis. (news-medical.net)
Hypercoagulability, also known as thrombophilia, refers higher levels of coagulation factors in the blood that increase susceptibility to thrombosis. (news-medical.net)
Injury to the epithelial cells on the wall of blood vessels after trauma, surgery or and infection can also precipitate coagulation and possible thrombosis. (news-medical.net)
Abnormal blood flow, such as venous stasis following heart failure or long periods of sedentary behavior, can also cause thrombosis to occur. (news-medical.net)
As stasis of the blood is associated with increased risk of thrombosis, it is important that movements are made regularly, particularly if susceptible individuals are likely to be sedentary for long periods of time, such as in bed or on an airplane. (news-medical.net)
The symptoms of thrombosis may look like other blood disorders or health problems. (uhhospitals.org)
This slow blood flow is probably what increases the risk of thrombosis. (eurekalert.org)
A thrombosis filter configured for placement within a blood vessel lumen. (google.co.uk)
The decrease in nitric oxide causes both white blood cells and platelets to bind to the endothelium, initiating the thrombosis. (medindia.net)
The Thrombosis Center brings together clinicians that specialize in blood clotting disorders . (clevelandclinic.org)
Cleveland Clinic's Thrombosis Center is dedicated to diagnosing and treating conditions related to thrombosis, often called hypercoagulable conditions, thrombophilia or blood clotting disorders. (clevelandclinic.org)

Although the authors do a credible job of describing the diverse causes of pediatric stroke and the controversies surrounding treatment of children, there was little emphasis on the danger of extreme hyperosmolar states and risks of thrombosis. (cmaj.ca)
At the same time, venous thrombosis is the third leading vascular diagnosis after heart attack and stroke. (burlingtonfreepress.com)
Considered an area of medicine that requires specific expertise, Children's specializes in care of children and adolescents with Hemophilia and other bleeding disorders, thrombosis and stroke and ITP. (nationwidechildrens.org)
The inflammatory component of thrombosis is a therapeutic gap and a promising target for the prevention and treatment of cardiovascular diseases such as myocardial infarction, stroke and venous thromboembolism. (nature.com)
Thrombosis is the often preventable underlying problems leading to heart attack, thromboembolic stroke, and venous thromboembolism (VTE), the top three cardiovascular killers. (punchng.com)
The symptoms of cerebral thrombosis are also the symptoms of stroke. (wisegeek.com)
biggest cause of disability in older age is - heart disease related medical events ie thrombosis, stroke, heart attack, aneurysm. (pinboard.in)

Venous thrombosis can occur for a number of reasons. (encyclopedia.com)

Retrieved on April 05, 2020 from https://www.news-medical.net/health/What-is-Thrombosis.aspx. (news-medical.net)

In several Swedish and Dutch populations, the prevalence of FVL was 2-7%, or about 10-fold higher than all previously identified genetic risk factors for thrombosis combined. (cdc.gov)
Do you agree that the relative risk of venous thrombosis in OC users was similar regardless of factor V genotype? (cdc.gov)
Jeff Burzynski raises an interesting point about the danger of the hyperosmolar state and risk of thrombosis. (cmaj.ca)
Obesity is also a major risk factor for venous thrombosis. (burlingtonfreepress.com)
Who is at risk for thrombosis? (uhhospitals.org)
As thrombosis is a significant cause of morbidity and mortality in cancer patients, it is important to identify and appropriately treat patients at higher risk, especially prior to chemotherapy or surgery. (nih.gov)
The risk of cerebral venous thrombosis (CVT) following COVID-19 infection is eight to ten times higher than after receiving a COVID-19 vaccination, researchers have said. (medworm.com)
Targeting inflammation to prevent thrombosis leaves haemostasis mainly unaffected, circumventing the risk of bleeding associated with current approaches. (nature.com)
Public Citizen filed its petition in May asking the agency to pull Ortho Evra from the market in part because of the increased risk of venous thrombosis compared with combined oral contraceptives. (thefreedictionary.com)
Jobst brochure entitled, Venous Thrombosis in the High-Risk Patient, Form 945 (1987). (google.com)
SAN FRANCISCO -- Having immune thrombocytopenia purpura (ITP) appears to increase the risk of thrombosis, a British researcher said here. (medpagetoday.com)
Although none of the hazard ratios met the standard for conventional statistical significance, Sarpatwari said he's convinced that at least the venous thrombosis risk is real. (medpagetoday.com)
Replies to an inquiry on the risk of thrombosis after splenectomy. (ebscohost.com)
Risk factors of thrombosis. (ebscohost.com)
Preventing cerebral thrombosis involves the modification of its risk factors, which include hypertension, diabetes , smoking, and alcohol consumption. (wisegeek.com)
Various risk factors increase the likelihood of any one individual developing a thrombosis. (wikipedia.org)

suggest that a positive D-dimer assay result predicts future clotting events in patients with SLE who lack symptoms of thrombosis. (medscape.com)
What are the symptoms of thrombosis? (uhhospitals.org)

The chance of developing cerebral venous sinus thrombosis was nearly 10 times higher in the two weeks following a diagnosis of SARS-CoV-2 infection than after receiving an mRNA vaccine, a data. (medworm.com)
Cleveland Clinic's Thrombosis Center is a multidisciplinary specialty treatment group dedicated to the diagnosis and treatment of hypercoagulable conditions or thrombophilia. (clevelandclinic.org)

Small-vessel thrombosis is used for thrombosis of smaller and deeper arteries, such as lacunar arteries. (wisegeek.com)
Large-vessel thrombosis is used for thrombosis of bigger arteries, such as the middle cerebral and carotid artery. (wisegeek.com)

Therefore, heparin offers greater use in the treatment, rather than prevention of thrombosis. (news-medical.net)
Penile thrombosis is usually treated with non-steroidal anti-inflammatory (NSAID) pain relievers and an ointment containing the anticoagulant heparin . (wisegeek.com)

Haeger K. Problems of acute deep venous thrombosis. (medscape.com)
Treatment of symptomatic lower extremity acute deep venous thrombosis: role of mechanical thrombectomy. (medscape.com)

In this Review, we discuss how the synergy between inflammation and thrombosis drives thrombotic diseases. (nature.com)
Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. (routledge.com)

Thrombosis affects people of all ages, races and ethnicities, and occurs in both men and women. (punchng.com)

Cavernous sinus thrombosis is a specialised form of cerebral venous sinus thrombosis, where there is thrombosis of the cavernous sinus of the basal skull dura, due to the retrograde spread of infection and endothelial damage from the danger triangle of the face. (wikipedia.org)
These images are a random sampling from a Bing search on the term "Cavernous Sinus Thrombosis. (fpnotebook.com)

There is significant controversy surrounding the dose of anticoagulant therapy, specifically whether the efficacy of dosages for prophylaxis of deep venous thrombosis outweighs the risks associated with full systemic anticoagulation. (cmaj.ca)
Contract notice: Supply of stockings for deep venous thrombosis prophylaxis and medical gloves. (thefreedictionary.com)
Prophylaxis for patients with thrombosis. (ebscohost.com)

The Hemostasis and Thrombosis Center at Nationwide Children's is the largest and only federally recognized pediatric Hemophilia Treatment Center's in Central Ohio. (nationwidechildrens.org)
The thrombosis filter of the present invention includes a body element, a plurality of struts, and a surface treatment. (google.co.uk)
The surface treatment, comprised in part of an anti-proliferative or anti-angiogenic drug, is applied to portions of the thrombosis filter in order to regulate neointimal growth around the thrombosis filter and its anchor elements. (google.co.uk)
The thrombosis filter may further contain a first and a second surface treatment layer. (google.co.uk)
a surface treatment covering at least a portion of the thrombosis filter, wherein the surface treatment comprises two layers, a first surface treatment layer located between a second surface treatment layer and the portion of the thrombosis filter, the first surface treatment layer having properties which enhance endothelial cell growth, and the second surface treatment layer including an anti-proliferative or anti-angiogenic drug. (google.co.uk)
4. A thrombosis filter element according to claim 1 , wherein the second surface treatment layer is dissolvable, wherein the dissolving rate may be varied depending upon the structure and composition of the second surface treatment layer. (google.co.uk)
5. A thrombosis filter element according to claim 1 , wherein the surface treatments incorporate, respectively, the anti-proliferative or anti-angiogenic drug and the endothelial cell growth enhancer with a bio-compatible polymeric material, or a combination of the surface treatment layers with or without the incorporation of the bio-compatible polymeric material. (google.co.uk)
6. A thrombosis filter element according to claim 1 , wherein the first and second surface treatment layers cover the plurality of free ends of the struts in contact with the vessel wall. (google.co.uk)
7. A thrombosis filter element according to claim 1 , wherein the surface treatments, or some combination of the first surface treatment layer and the second surface treatment layer, are coated upon at least a portion of the thrombosis filter element through a dipping or spraying process. (google.co.uk)
an anti-proliferative or anti-angiogenic drug constituting a surface treatment covering at least a portion of the thrombosis filter element, wherein the surface treatment may cover the entire or only discrete regions of the thrombosis filter element, wherein the surface treatment incorporates the anti-proliferative or anti-angiogenic drug with a biocompatible polymeric material, wherein the bio-compatible polymeric material is biodegradable. (google.co.uk)
The acquisition of Calimmune Inc., introduced a new ex vivo hematopoietic stem cell gene therapy (CAL-H/CSL200) for the treatment of sickle cell disease (SCD) into our hematology and thrombosis pipeline. (cslbehring.com)

The prevalence of activated protein C resistance was 20%-60% in selected groups of patients with venous thrombosis, depending on selection criteria. (cdc.gov)
According to a report from NewScientist.com , Beasley's team is to review the records of other patients who had pulmonary embolisms to see if they can find other cases of e-thrombosis. (zdnet.com)
This Practice Point commentary considers whether the D-dimer assay will remain simply a tool to rule out thrombosis in symptomatic patients with SLE or whether it could eventually be used to initiate preventive anticoagulation in asymptomatic patients. (medscape.com)
Worly and associates 2 described 3 patients aged 14-18 months with DKA and calculated serum osmolarity of 291-356 mOsm/L who experienced deep venous thrombosis associated with central venous femoral catheters. (cmaj.ca)
Usefulness of CT Angiography for Therapeutic Decision Making in Thrombolyzing Intubated Patients with Suspected Basilar Artery Thrombosis. (medscape.com)
Of patients evaluated for deep venous thrombosis (DVT) of the lower extremity, only a quarter of them have the disease. (medscape.com)
Useche JN, de Castro AM, Galvis GE, Mantilla RA, Ariza A. Use of US in the evaluation of patients with symptoms of deep venous thrombosis of the lower extremities. (medscape.com)
Several reports have described venous thrombosis in testicular cancer patients during chemotherapy. (thefreedictionary.com)
Patients with APS have circulating antibodies that cause exaggerated thrombosis. (medindia.net)
Patients with thrombosis often require lifelong anti-coagulation therapy," he said. (medindia.net)
Each year we see more than 6,000 patients in the Thrombosis Center. (clevelandclinic.org)
Background and Purpose- The natural history, causative factors, and outcomes of patients with cerebral venous thrombosis from Asia and Middle East have not been well described. (ahajournals.org)
This descriptive multicenter study describes the results for cerebral venous thrombosis patients in South Asia and the Middle East. (ahajournals.org)
Methods- The retrospective and prospective data of patients with radiologically confirmed cerebral venous thrombosis were collected from 4 centers located in Pakistan and United Arab Emirates. (ahajournals.org)
Patients with CAT tell us they feel that neither in one camp or the other - oncology or thrombosis (haematology) - and struggle with obtaining clear information on CAT. (warwick.ac.uk)

Worly JM, Fortenberry JD, Hansen I, Chambliss CR, Stockwell J. Deep venous thrombosis in children with diabetic ketoacidosis and femoral central venous catheters. (cmaj.ca)
Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis. (cmaj.ca)

Dr. Mary Cushman, director, Thrombosis and Hemostasis Program, Fletcher Allen Health Care and Professor of Medicine, University of Vermont. (burlingtonfreepress.com)

Surgical Strategy for Hepatocellular Carcinoma Patients with Portal/Hepatic Vein Tumor Thrombosis (journals.plos.org)

Quiz: Deep Vein Thrombosis - Merck Manuals Consumer Version (merckmanuals.com)

When Thrombosis Strikes: Evaluation, Management, And Counseling | Audio Digest (audio-digest.org)

Educate Youreself On Causes And Treatments Of Scars And Wrinkles, Deep Vein Thrombosis (scintera.com.au)

Travel Yoga, Holiday stress relief, Avoid Deep Vein Thrombosis (drivetimeyoga.com)

JCDR - Nephrotic syndrome, Platelet aggregation, Deep Vein Thrombosis, Hypercoagulable State, Coagulation profile (jcdr.net)

Anatomy31

Organisms3

Diseases67

Chemicals and Drugs68

Analytical, Diagnostic and Therapeutic Techniques and Equipment74

Phenomena and Processes20

Technology, Industry, Agriculture2

Information Science3

Health Care16

Systemic infection with Alaria americana (Trematoda). (1/5349)

Antiphospholipid, anti-beta 2-glycoprotein-I and anti-oxidized-low-density-lipoprotein antibodies in antiphospholipid syndrome. (2/5349)

Blood-borne tissue factor: another view of thrombosis. (3/5349)

Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. (4/5349)

The tourniquet in total knee arthroplasty. A prospective, randomised study. (5/5349)

The value of late computed tomographic scanning in identification of vascular abnormalities after abdominal aortic aneurysm repair. (6/5349)

Immunohistochemical analysis of arterial wall cellular infiltration in Buerger's disease (endarteritis obliterans). (7/5349)

The intrarenal vascular lesions associated with primary antiphospholipid syndrome. (8/5349)

Thrombosis

Venous Thrombosis

Coronary Thrombosis

Sinus Thrombosis, Intracranial

Intracranial Thrombosis

Carotid Artery Thrombosis

Anticoagulants

Sagittal Sinus Thrombosis

Phlebography

Intracranial Embolism and Thrombosis

Iliac Vein

Thrombophilia

Femoral Vein

Upper Extremity Deep Vein Thrombosis

Portal Vein

Cerebral Veins

Heparin

Factor V

Fibrinolytic Agents

Hemostasis

Heparin, Low-Molecular-Weight

Cavernous Sinus Thrombosis

Blood Coagulation

Antiphospholipid Syndrome

Vena Cava, Inferior

Thromboembolism

Platelet Aggregation Inhibitors

Lateral Sinus Thrombosis

Bleeding Time

Thrombectomy

Fibrin Fibrinogen Degradation Products

Stents

Protein S Deficiency

Treatment Outcome

Platelet Aggregation

Mesenteric Veins

Subclavian Vein

Drug-Eluting Stents

Prothrombin

Risk Factors

Popliteal Vein

Jugular Veins

Blood Platelets

Venous Thromboembolism

Hemorrhage

Antibodies, Antiphospholipid

Protein C Deficiency

Cranial Sinuses

Activated Protein C Resistance

Lupus Coagulation Inhibitor

Platelet Activation

Thromboplastin

Time Factors

Thrombolytic Therapy

Warfarin

Follow-Up Studies

Renal Veins

Splenic Vein

Ultrasonography, Doppler, Duplex

Budd-Chiari Syndrome

Antithrombin III Deficiency

Retrospective Studies

Fibrinolysis

Axillary Vein

Mesenteric Vascular Occlusion

Protein C

Postthrombotic Syndrome

Aspirin

Catheterization, Central Venous

Graft Occlusion, Vascular

Fibrin

Vena Cava Filters

Fibrinogen

Postphlebitic Syndrome

Antithrombins

Arteriovenous Shunt, Surgical

Prospective Studies

Ticlopidine

Partial Thromboplastin Time

Recurrence