AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
ThiazolesThiamineBenzothiazolesThiostreptonThiamine PyrophosphateFANFTThiamine TriphosphateCarbon-Nitrogen LyasesQuinolinesMolecular StructureHydrazonesSulfurtransferasesSulfur CompoundsOxathiinsHeterocyclic CompoundsQuantitative Structure-Activity RelationshipIntercalating AgentsFluorescent DyesStructure-Activity RelationshipMacrocyclic CompoundsBacteriocinsCyclizationDrug Screening Assays, AntitumorNucleotidyltransferasesBiocatalysisParasitic Sensitivity TestsMagnetic Resonance SpectroscopyAnti-Bacterial AgentsCell Line, TumorPeptidesPeptides, CyclicPyrimidinesModels, MolecularEscherichia coliMolecular Sequence DataSalmonella typhimuriumModels, ChemicalAntineoplastic AgentsEscherichia coli ProteinsDNA
Thiazoles
Thiamine
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
Benzothiazoles
Compounds with a benzene ring fused to a thiazole ring.
Thiostrepton
One of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.
Thiamine Pyrophosphate
The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
FANFT
A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
Thiamine Triphosphate
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
Carbon-Nitrogen Lyases
Enzymes that catalyze the cleavage of a carbon-nitrogen bond by means other than hydrolysis or oxidation. Subclasses are the AMMONIA-LYASES, the AMIDINE-LYASES, the amine-lyases, and other carbon-nitrogen lyases. EC 4.3.
Quinolines
Molecular Structure
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Hydrazones
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
Sulfurtransferases
Enzymes which transfer sulfur atoms to various acceptor molecules. EC 2.8.1.
Sulfur Compounds
Inorganic or organic compounds that contain sulfur as an integral part of the molecule.
Oxathiins
Heterocyclic Compounds
Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)
Quantitative Structure-Activity Relationship
A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity information gathered from a series of similar compounds.
Intercalating Agents
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
Fluorescent Dyes
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Structure-Activity Relationship
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
Macrocyclic Compounds
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
Bacteriocins
Substances elaborated by specific strains of bacteria that are lethal against other strains of the same or related species. They are protein or lipopolysaccharide-protein complexes used in taxonomy studies of bacteria.
Cyclization
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Drug Screening Assays, Antitumor
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Nucleotidyltransferases
A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.
Biocatalysis
The facilitation of biochemical reactions with the aid of naturally occurring catalysts such as ENZYMES.
Parasitic Sensitivity Tests
Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
Magnetic Resonance Spectroscopy
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Cell Line, Tumor
A cell line derived from cultured tumor cells.
Peptides
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Peptides, Cyclic
Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).
Pyrimidines
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
Models, Molecular
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Salmonella typhimurium
A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.
Models, Chemical
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Escherichia coli Proteins
Proteins obtained from ESCHERICHIA COLI.
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Carbon disulphide absorption during xanthate reagent mixing in a gold mine concentrator. (1/5377)

A xanthate reagent mixer at a gold mine concentrator was exposed to carbon disulphide by extensive skin contamination with xanthate powder and solution during the reagent mixing process. Absorption of carbon disulphide was confirmed by the detection of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA). Drager colorimetric tube testing during subsequent mixing recorded a maximum concentration of at least 60 ppm carbon disulphide. An illness consisting of predominantly gastrointestinal symptoms began 20 h after the exposure. Although this may have been due to carbon disulphide toxicity this is by no means certain. The need for engineering controls, impervious protective clothing and full-face respirators with particulate and organic vapour cartridges is discussed. This episode occurred at another mine site, unrelated to Mount Isa Mines Limited.  (+info)

Acute troglitazone action in isolated perfused rat liver. (2/5377)

1. The thiazolidinedione compound, troglitazone, enhances insulin action and reduces plasma glucose concentrations when administered chronically to type 2 diabetic patients. 2. To analyse to what extent thiazolidinediones interfere with liver function, we examined the acute actions of troglitazone (0.61 and 3.15 microM) on hepatic glucose and lactate fluxes, bile secretion, and portal pressure under basal, insulin- and/or glucagon-stimulated conditions in isolated perfused rat livers. 3. During BSA-free perfusion, high dose troglitazone increased basal (P < 0.01), but inhibited glucagon-stimulated incremental glucose production by approximately 75% (10.0 +/- 2.5 vs control: 40.0 +/- 7.2 micromol g liver(-1), P < 0.01). In parallel, incremental lactate release rose approximately 6 fold (13.1 +/- 5.9 vs control: 2.2 +/- 0.8 mmol g liver(-1), P < 0.05), while bile secretion declined by approximately 67% [0.23 +/- 0.02 vs control: 0.70 +/- 0.05 mg g liver(-1) min(-1)), P < 0.001]. Low dose troglitazone infusion did not enhance the inhibitory effect of insulin on glucagon-stimulated glucose production, but rapidly increased lactate release (P < 0.0005) and portal venous pressure (+0.17 +/- 0.07 vs +0.54 +/- 0.07 cm buffer height, P < 0.0001). 4. These results indicate that troglitazone exerts both insulin-like and non-insulin-like hepatic effects, which are blunted by addition of albumin, possibly due to troglitazone binding.  (+info)

Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27. (3/5377)

Mast cells are widely distributed in human tissues, including the human uterus. However, the function of mast cells in uterine smooth muscle has not been clearly established. Mast cells possess secretory granules containing such substances as heparin, serotonin, histamine and many cytokines. To help establish the role of mast cells in the human myometrium, the action of heparin was investigated using smooth muscle cells (SMC) from normal myometrium and from leiomyoma. The proliferation of cultured myometrial and leiomyomal SMC was inhibited by heparin treatment. Flow cytometric analysis showed that the population in the G1 phase of the cell cycle increased under heparin treatment. Western blotting analysis showed that markers of SMC differentiation such as alpha-smooth muscle actin (alpha-SMA), calponin h1 and cyclin-dependent kinase inhibitor p27 were induced by heparin, whereas cell-cycle-related gene products from the G1 phase of the cell cycle, such as cyclin E and cdk2, were not changed. Taken together, these results indicate that heparin inhibits the proliferation of myometrial and leiomyomal SMC through the induction of alpha-SMA, calponin h1 and p27. We suggest that heparin from mast cells may induce differentiation in uterine SMC and may influence tissue remodelling and reconstruction during physiological and pathophysiological events.  (+info)

Latrunculin-A causes mydriasis and cycloplegia in the cynomolgus monkey. (4/5377)

PURPOSE: To determine the effect of latrunculin (LAT)-A, which binds to G-actin and disassembles actin filaments, on the pupil, accommodation, and isolated ciliary muscle (CM) contraction in monkeys. METHODS: Pupil diameter (vernier calipers) and refraction (coincidence refractometry) were measured every 15 minutes from 0.75 to 3.5 hours after topical LAT-A 42 microg (approximately 10 microM in the anterior chamber [AC]). Refraction was measured every 5 minutes from 0.5 to 1.5 hours after intracameral injection of 10 microl of 50 microM LAT-A (approximately 5 microM in AC), with intramuscular infusion of 1.5 mg/kg pilocarpine HCl (PILO) during the first 15 minutes of measurements. Pupil diameter was measured at 1 and 2 hours, and refraction was measured every 5 minutes from 1 to 2 hours, after intravitreal injection of 20 microl of 1.25 mM LAT-A (approximately 10 microM in vitreous), with intramuscular infusion of 1.5 mg/kg PILO during the first 15 minutes of measurements (all after topical 2.5% phenylephrine), and contractile response of isolated CM strips, obtained <1 hour postmortem and mounted in a perfusion apparatus, to 10 microM PILO +/- LAT-A was measured at various concentrations. RESULTS: Topical LAT-A of 42 microg dilated the pupil without affecting refraction. Intracameral LAT-A of 5 microM inhibited miotic and accommodative responses to intramuscular PILO. Intravitreal LAT-A of 10 microM had no effect on accommodative or miotic responses to intramuscular PILO. LAT-A dose-dependently relaxed the PILO-contracted CM by up to 50% at 3 microM in both the longitudinal and circular vectors. CONCLUSIONS: In monkeys, LAT-A causes mydriasis and cycloplegia, perhaps related to its known ability to disrupt the actin microfilament network and consequently to affect cell contractility and adhesion. Effects of LAT-A on the iris and CM may have significant physiological and clinical implications.  (+info)

Mechanism of weight gain suppressing effect of ER-40133, an angiotensin I converting enzyme inhibitor, in growing rats. (5/5377)

Effects of ER-40133, an inhibitor of angiotensin converting enzyme (ACE), on weight gain and sodium and potassium balance were studied in growing SD male rats. Thirty-two animals (seven weeks of age) were divided into two groups; one received a standard diet containing 0.227% sodium and the other a low (0.065%) sodium diet. They were divided into four subgroups; one control group and three treated groups receiving 3, 10 or 30 mg/kg of ER-40133, by gavage, once a day for five consecutive days. Body weight gain (average of the standard and low sodium diet groups) was -32% in the 3 mg/kg group,-74% in 10 mg/kg group and -99% in 30 mg/kg group, when compared with the control group. There was a highly linear correlation between suppression of body weight gain and reduction in sodium and potassium retention for both groups of animals given the standard and low sodium diet. The reduced sodium retention, the primary effect of ACE inhibitors, accounted for about 30% of suppressed weight gain, and the reduced potassium retention, the secondary effect of sodium deficiency, could account for the rest about 70% of weight suppression by ER-40133.  (+info)

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively. (6/5377)

The nuclear peroxisome proliferator-activated receptor gamma (PPARgamma) activates the transcription of multiple genes involved in intra- and extracellular lipid metabolism. Several cofactors are crucial for the stimulation or the silencing of nuclear receptor transcriptional activities. The two homologous cofactors p300 and CREB-binding protein (CBP) have been shown to co-activate the ligand-dependent transcriptional activities of several nuclear receptors as well as the ligand-independent transcriptional activity of the androgen receptor. We show here that the interaction between p300/CBP and PPARgamma is complex and involves multiple domains in each protein. p300/CBP not only bind in a ligand-dependent manner to the DEF region of PPARgamma but also bind directly in a ligand-independent manner to a region in the AB domain localized between residue 31 to 99. In transfection experiments, p300/CBP could thereby enhance the transcriptional activities of both the activating function (AF)-1 and AF-2 domains. p300/CBP displays itself at least two docking sites for PPARgamma located in its N terminus (between residues 1 and 113 for CBP) and in the middle of the protein (between residues 1099 and 1460).  (+info)

L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding. (7/5377)

Insulin-sensitizing thiazolidinedione (TZD) compounds are high affinity ligands for a member of the nuclear receptor family, peroxisome proliferator-activated receptor (PPAR) gamma. A scintillation proximity assay for measurement of 3H-radiolabeled TZD binding to human PPARgamma under homogeneous conditions was developed. Using this approach, a novel non-TZD compound (L-764406) was shown to be a potent (apparent binding IC50 of 70 nM) PPARgamma ligand. Preincubation of PPARgamma with L-764406 prevented binding of the [3H]TZD, suggesting a covalent interaction with the receptor; in addition, structurally related analogues of L-764406, which would be predicted not to interact with PPARgamma in a covalent fashion, did not displace [3H]TZD binding to PPARgamma. Covalent binding of L-764406 was proven by an observed molecular weight shift of a tryptic PPARgamma ligand binding domain (LBD) peptide by mass spectrometric analysis. A specific cysteine residue (Cys313 in helix 3 of hPPARgamma2) was identified as the attachment site for this compound. In protease protection experiments, the liganded receptor adopted a typical agonist conformation. L-764406 exhibited partial agonist activity in cells expressing a chimeric receptor containing the PPARgamma LBD and a cognate reporter gene and also induced the expression of the adipocyte-specific gene aP2 in 3T3-L1 cells. In contrast, L-764406 did not exhibit activity in cells transfected with chimeric receptors containing PPARalpha or PPARdelta LBDs. The partial agonist properties of L-764406 were also evident in a co-activator association assay, indicating that the increased transcription in cells was co-activator mediated. Thus, L-764406 is a novel non-TZD ligand for PPARgamma and is also the first known partial agonist for this receptor. The results suggest a critical functional role for Cys313, and helix 3, in contributing to ligand binding and subsequent agonist-induced conformational changes.  (+info)

Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts. (8/5377)

Troglitazone is a thiazolidinedione used for the treatment of NIDDM and potentially for other insulin-resistant disease states. Troglitazone has recently been shown to increase cardiac output and stroke volume in human subjects. These actions are thought to be mediated by the reduction of peripheral resistance, but a potential direct effect on cardiac function has not been studied. Therefore, we investigated the direct cardiac hemodynamic effects of troglitazone in isolated perfused rat hearts. Five groups of hearts were studied. Hearts were tested under isovolumetric contraction with a constant coronary flow, and troglitazone (0.2, 0.5, and 1.0 micromol) was administered by bolus injection. Peak isovolumetric left ventricular pressure (LVPmax), peak rate of rise of LVP (dP/dt(max)), and peak rate of fall of LVP (dP/dt(min)) were significantly increased 1 min after troglitazone administration in a dose-dependent manner, while the heart rate (HR) and coronary perfusion pressure (CPP) were significantly decreased (P < 0.05). HR was then fixed by pacing and/or CPP was fixed with nitroprusside to eliminate any effect of the two variables on the action of troglitazone. With constant HR and/or constant CPP, the effect of troglitazone on LVPmax, dP/dt(max), and dP/dt(min) was still unchanged. In addition, the positive inotropic, positive lusitropic, and negative chronotropic actions of troglitazone were not influenced even when hearts were pretreated with prazosin, propranolol, or nifedipine. In conclusion, troglitazone has direct positive inotropic, positive lusitropic, negative chronotropic, and coronary artery dilating effects. The inotropic and chronotropic actions of troglitazone are not mediated via adrenergic receptors or calcium channels. These findings have important clinical implications for diabetic patients with congestive heart failure.  (+info)

2-Mercapto thiazoline, China 2-Mercapto thiazoline, 2-Mercapto thiazoline exporters, China 2-Mercapto thiazoline Suppliers -...
We, China 2-Mercapto thiazoline Manufacturers, China 2-Mercapto thiazoline Suppliers, provide quality 2-Mercapto thiazoline product and the products related with China 2-Mercapto thiazoline - nwchemical
http://www.chinachemnet.com/38045/2-mercapto-thiazoline-1617530.html
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapyClonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
article{f635f2cb-0638-4e22-adf6-fccd64151250, abstract = {Dasatinib, a broad-spectrum tyrosine kinase inhibitor (TKI), predominantly targets BCR-ABL and SRC oncoproteins and also inhibits off-target kinases, which may result in unexpected drug responses. We identified 22 patients with marked lymphoproliferation in blood while on dasatinib therapy. Clonality and immunophenotype were analyzed and related clinical information was collected. An abrupt lymphocytosis (peak count range 4-20 x 10(9)/l) with large granular lymphocyte (LGL) morphology was observed after a median of 3 months from the start of therapy and it persisted throughout the therapy. Fifteen patients had a cytotoxic T-cell and seven patients had an NK-cell phenotype. All T-cell expansions were clonal. Adverse effects, such as colitis and pleuritis, were common (18 of 22 patients) and were preceded by LGL lymphocytosis. Accumulation of identical cytotoxic T cells was also detected in pleural effusion and colon biopsy samples. ...
https://lup.lub.lu.se/search/publication/1478172
Thiazoles - Halogenated Heterocycles | Sigma-AldrichThiazoles - Halogenated Heterocycles | Sigma-Aldrich
Thiazoles and their derivatives have been frequently discovered as a vital component of novel and structurally diverse natural products that exhibit a wide variety of biological activities. The exceptional range of antitumor, antiviral, and antibiotic activities, as well as their presence in peptides, or ability to bind to proteins, DNA, and RNA, have directed numerous synthetic studies and new applications of these heterocycles.The thiazole ring has been identified as a central feature of a myriad of natural products, perhaps the best known being the epothilones. Additionally, thiazoles are frequently appearing in peptide research. Thiazoles can also serve as a protected formyl group that can be liberated in the late stages of a complex natural product synthesis. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.Learn More about Thiazoles
https://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16272144
Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity<...
TY - JOUR. T1 - Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity. AU - Takasu, Kiyosei. AU - Inoue, Hiroshi. AU - Kim, Hye Sook. AU - Suzuki, Makoto. AU - Shishido, Tadao. AU - Wataya, Yusuke. AU - Ihara, Masataka. PY - 2002/2/28. Y1 - 2002/2/28. N2 - The rhodacyanine dye MKT-077 (1), a potent antitumor agent, was found to possess strong in vitro activity against Plasmodium falciparum and a low cytotoxicity. Several new rhodacyanine dyes related to 1, containing a variety of linked heterocyclic moieties, were synthesized, and their antimalarial potencies were evaluated. The synthetic rhodacyanines were found to have EC50 values against P. falciparum in vitro in the range of 4-300 nM. Several compounds in this series have remarkable selective toxicity profiles (, 100).. AB - The rhodacyanine dye MKT-077 (1), a potent antitumor agent, was found to possess strong in vitro activity against Plasmodium falciparum and a low cytotoxicity. Several new ...
https://okayama.pure.elsevier.com/en/publications/rhodacyanine-dyes-as-antimalarials-1-preliminary-evaluation-of-th
2-(4-Aminophenyl)-6-hydroxynaphtho[2,1-d]thiazole-8-sulfonic acid - Alfa Chemistry2-(4-Aminophenyl)-6-hydroxynaphtho[2,1-d]thiazole-8-sulfonic acid - Alfa Chemistry
Alfa Chemistry is the worlds leading provider for special chemicals. We offer qualified products for 6259-72-9(2-(4-aminophenyl)-6-hydroxynaphtho[2,1-d]thiazole-8-sulfonic acid),please inquire us for 6259-72-9(2-(4-aminophenyl)-6-hydroxynaphtho[2,1-d]thiazole-8-sulfonic acid).
http://www.alfa-chemistry.com/cas_6259-72-9.htm
THIAZOLE-5-FORMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF - XIANGBEI WELMAN PHARMACEUTICAL CO LTDTHIAZOLE-5-FORMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF - XIANGBEI WELMAN PHARMACEUTICAL CO LTD
The present invention relates to a thiazole-5-formic acid derivative, a stereoisomer and a pharmaceutically acceptable salt thereof, the structure of the thiazole-5-formic acid derivative being represented by general formula (I). The compound of the general formula (I), the stereoisomer thereof and/or the pharmaceutically acceptable salt thereof of the present invention can be used to prepare a medicament for preventing or treating hyperuricemia and/or gout, and can be prepared to dosage forms for various routes of administration. The compounds provided in the present invention have good tolerance, safety and excellent uric acid reducing activities.
http://www.sumobrain.com/patents/wipo/Thiazole-5-formic-acid-derivative/WO2019144842A1.html
4-methyl-5-thiazole ethanol | Article about 4-methyl-5-thiazole ethanol by The Free Dictionary4-methyl-5-thiazole ethanol | Article about 4-methyl-5-thiazole ethanol by The Free Dictionary
Looking for 4-methyl-5-thiazole ethanol? Find out information about 4-methyl-5-thiazole ethanol. C6H9NOS A viscous, oily liquid; soluble in alcohol, ether, benzene, chloroform, and water; used as an intermediate in the synthesis of vitamin B1 and as a... Explanation of 4-methyl-5-thiazole ethanol
http://encyclopedia2.thefreedictionary.com/4-methyl-5-thiazole+ethanol
China 2016 Hot Effecient Bacteriacide, Bismerthiazol & Zn Thiazole - China Bismerthiazol, Zn ThiazoleChina 2016 Hot Effecient Bacteriacide, Bismerthiazol & Zn Thiazole - China Bismerthiazol, Zn Thiazole
China 2016 Hot Effecient Bacteriacide, Bismerthiazol & Zn Thiazole, Find details about China Bismerthiazol, Zn Thiazole from 2016 Hot Effecient Bacteriacide, Bismerthiazol & Zn Thiazole - Shanghai Fuang Agrochemical Co. Ltd.
http://fuangagrochemical.en.made-in-china.com/product/gvFnYQhOAsWL/China-2016-Hot-Effecient-Bacteriacide-Bismerthiazol-Zn-Thiazole.html
Some thiazole derivatives as potent antiproliferative agents with CDK2/Cycin E/A inhibitory activities Poster | Technology...Some thiazole derivatives as potent antiproliferative agents with CDK2/Cycin E/A inhibitory activities Poster | Technology...
We report synthesis and biological evaluation of novel thiazole derivatives. High throughput screening of various compounds for their anti-proliferative activity led to the identification of thiazolo-thiones as potential candidate for Lung cancer (NCl-H23, NClH510A, NCI-H522) and breast cancer (MDA-MB-453/231/468, MCF-7). The most potent compounds were also screened for their inhibitory activity against CDK2/ Cyclin E/A which are considered as promising targets for lung and breast cancer.
https://www.technologynetworks.com/neuroscience/posters/some-thiazole-derivatives-as-potent-antiproliferative-agents-with-cdk2cycin-ea-inhibitory-activities-230170
Computer Based Design And Synthesis OF Some Novel THiazole Derivatives Bearing a Sulfonamide Moiety and Studying Their...Computer Based Design And Synthesis OF Some Novel THiazole Derivatives Bearing a Sulfonamide Moiety and Studying Their...
Thesis, English, Computer Based Design And Synthesis OF Some Novel THiazole Derivatives Bearing a Sulfonamide Moiety and Studying Their Potential Synergistic Anticancer Effect With Irradiation for Aiten Mahmoud Mohamed
http://www.philadelphia.edu.jo/newlibrary/eng/english-books/671-english-books/93345-engb-93345
Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97% 10g Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97%Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97% 10g Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97%
Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97% 10g Alfa Aesar™ 2-Amino-4-(3-pyridyl)thiazole, 97% Aminophenyls to Aminotetra -Organics
https://www.fishersci.co.uk/shop/products/2-amino-4-3-pyridyl-thiazole-97-1/15404878
4-(bromomethyl)-2-methyl-1,3-thiazole 74704-39-5 H-NMR | C-NMR Spectral Analysis NMR Spectrum4-(bromomethyl)-2-methyl-1,3-thiazole 74704-39-5 H-NMR | C-NMR Spectral Analysis NMR Spectrum
4-(bromomethyl)-2-methyl-1,3-thiazole 74704-39-5 NMR spectrum, 4-(bromomethyl)-2-methyl-1,3-thiazole H-NMR spectral analysis, 4-(bromomethyl)-2-methyl-1,3-thiazole C-NMR spectral analysis ect.
http://www.molbase.com/en/hnmr_74704-39-5-moldata-1545.html
2-Methylthieno[2,3-d]thiazole 61612-02-0 H-NMR | C-NMR Spectral Analysis NMR Spectrum2-Methylthieno[2,3-d]thiazole 61612-02-0 H-NMR | C-NMR Spectral Analysis NMR Spectrum
2-Methylthieno[2,3-d]thiazole 61612-02-0 NMR spectrum, 2-Methylthieno[2,3-d]thiazole H-NMR spectral analysis, 2-Methylthieno[2,3-d]thiazole C-NMR spectral analysis ect.
http://www.molbase.com/en/hnmr_61612-02-0-moldata-22468.html
Accela Chembio Inc 4-(2-NITROPHENYL)THIAZOLE 5G 4-(2-NITROPHENYL)THIAZOLE | Fisher ScientificAccela Chembio Inc 4-(2-NITROPHENYL)THIAZOLE 5G 4-(2-NITROPHENYL)THIAZOLE | Fisher Scientific
Shop a large selection of products and learn more about Accela Chembio Inc 4-(2-NITROPHENYL)THIAZOLE 5G 4-(2-NITROPHENYL)THIAZOLE .
https://www.fishersci.com/shop/products/4-2-nitrophenyl-thiazole-5g/50250640
Download Chemistry of Heterocyclic Compounds: Thiazole and Its by Metzger PDF - MAXLIFECO.COM Books
30e V for the second: it corresponds to the ionization of the lone pair of the amino group that is conjugated with the ring T system. 75 eV. 5 eV corresponding to the nitro group. All the assignments could be confirmed with good precision by CNDO/S calculations (Table 1-20). Bernardi et al. (131) have studied the halogen derivatives experimentally and theoretically. The experimental assignments have been compared successfully to theoretical results obtained by ab initio STO-3G and 4-31G methods (192, 193). Various isotopically labeled thiazoles have been synthezised for physicochemical purposes: 2- and 5-deutero and 25 I. 6N D2S0, at 118 for 8 days (111). 5 moles of nondeuterated thiazole, resulted from the thermal decarboxylation of thiazol-4-yldeuterocarboxylicacid (1 13). N-Thiazole was prepared from labeled thiourea through the Hantzsch cyclization with 1,2-dichloroethoxyethane, Sandmeyer bromination of the 2-aminothiazole, and reduction by zinc and acetic acid of the 15N-2-bromothiazole ...
http://maxlifeco.com/lib/chemistry-of-heterocyclic-compounds-thiazole-and-its-derivatives-part-one
4-(3-Amino-phenyl)-thiazole-2-carboxylic acid methyl ester - Alfa Chemistry4-(3-Amino-phenyl)-thiazole-2-carboxylic acid methyl ester - Alfa Chemistry
4-(3-Amino-phenyl)-thiazole-2-carboxylic acid methyl ester/AFI885279721 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
http://www.alfa-chemistry.com/cas_885279-72-1.htm
methyl 4,5-dimethyl-2,5-dihydro-1,3-thiazole-2-carboxylate | C7H11NO2S - ChemSynthesis
methyl 4,5-dimethyl-2,5-dihydro-1,3-thiazole-2-carboxylate - chemical structural formula, chemical names, chemical properties, synthesis references
http://www.chemsynthesis.com/base/chemical-structure-22885.html
Frontier Scientific 100g 2-(tert-butoxycarbonylamino)thiazole-5-carboxylic | Fisher ScientificFrontier Scientific 100g 2-(tert-butoxycarbonylamino)thiazole-5-carboxylic | Fisher Scientific
Frontier Scientific 100g 2-(tert-butoxycarbonylamino)thiazole-5-carboxylic acid, 302964-02-9 MFCD06796614 2-(TERT-BUTOXYCARBONYLAMIN100G
https://www.fishersci.com/shop/products/2-tert-butoxycarbonylamin100g/501380313
N-Propyl-5-(3-phenyl-4-pyridyl)thiazole-2-amine | C17H17N3S - PubChemN-Propyl-5-(3-phenyl-4-pyridyl)thiazole-2-amine | C17H17N3S - PubChem
N-Propyl-5-(3-phenyl-4-pyridyl)thiazole-2-amine | C17H17N3S | CID 117918945 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/117918945
2-amino-5-2-furyl-1-3-thiazole-4-carboxylic-acid | VWR2-amino-5-2-furyl-1-3-thiazole-4-carboxylic-acid | VWR
Learn more about 2-amino-5-2-furyl-1-3-thiazole-4-carboxylic-acid. We enable science by offering product choice, services, process excellence and our people make it happen.
https://us.vwr.com/store/product/21172161/2-amino-5-2-furyl-1-3-thiazole-4-carboxylic-acid
1-3-thiazole-2-carboxylic-acid-sodium-salt | VWR1-3-thiazole-2-carboxylic-acid-sodium-salt | VWR
Learn more about 1-3-thiazole-2-carboxylic-acid-sodium-salt. We enable science by offering product choice, services, process excellence and our people make it happen.
https://us.vwr.com/store/product/21151120/1-3-thiazole-2-carboxylic-acid-sodium-salt
IJMS | Free Full-Text | In Silico Identification of Structure Requirement for Novel Thiazole and Oxazole Derivatives as Potent...IJMS | Free Full-Text | In Silico Identification of Structure Requirement for Novel Thiazole and Oxazole Derivatives as Potent...
Fructose 1,6-bisphosphatase (FBPase) has been identified as a drug discovery target for lowering glucose in type 2 diabetes mellitus. In this study, a large series of 105 FBPase inhibitors were studied using a combinational method by 3D-QSAR, molecular docking and molecular dynamics simulations for a further improvement in potency. The optimal 3D models exhibit high statistical significance of the results, especially for the CoMFA results with rncv2, q2 values of 0.986, 0.514 for internal validation, and rpred2, rm2 statistics of 0.902, 0.828 statistics for external validation. Graphic representation of the results, as contoured 3D coefficient plots, also provides a clue to the reasonable modification of molecules. (1) Substituents with a proper length and size at the C5 position of the thiazole core are required to enhance the potency; (2) A small and electron-withdrawing group at the C2 position linked to the thiazole core is likely to help increase the FBPase inhibition; (3) Substituent groups as
http://www.mdpi.com/1422-0067/12/11/8161
Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit - Full...Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit - Full...
Masitinib is a selective tyrosine kinase inhibitor with potent activity against the juxta membrane domain of c-Kit. Masitinib is also thought to promote survival via modulation of immunostimulation-mediated anticancer effects and modulation of the tumor microenvironment. The objective of this study was to evaluate the efficacy and safety of masitinib with respect to dacarbazine in the treatment of non-resectable or metastatic stage 3 or stage 4 melanoma carrying a mutation in the juxta membrane domain of c-Kit. Following a protocol amendment, the dacarbarzine treatment group was closed and recruitment restricted to masitinib treatment of chemo-naïve (first-line) patients ...
https://www.clinicaltrials.gov/ct2/show/NCT01280565?term=melanoma+phase+III&rank=100
A Phase 3 Study to Compare Efficacy and Safety of Masitinib in Combination With Gemcitabine, to Placebo in Combination With...A Phase 3 Study to Compare Efficacy and Safety of Masitinib in Combination With Gemcitabine, to Placebo in Combination With...
Human pancreatic cancer overexpresses a number of important tyrosine kinase (TK) growth factors receptors and ligands, including expression of both PDGF and PDGF receptors. Drugs that can selectively inhibit TKs are likely to be of benefit in pancreatic cancer. Masitinib is a TK inhibitor, selectively and effectively inhibiting c-Kit (mast cell growth factor receptor), PDGF receptor, FGF receptor and to a lower extent the FAK kinases. Pre-clinical and clinical studies have shown that masitinib can reverse resistance of pancreatic tumor cell lines to gemcitabine. Based on pre-clinical and phase 2 clinical studies, masitinib can be considered as a good candidate to use in combination with gemcitabine in the treatment of pancreatic cancer ...
https://clinicaltrials.gov/show/NCT00789633
Synthesis, Characterization and Antimicrobial Activity of Some Oxazole and Thiazole DerivativesSynthesis, Characterization and Antimicrobial Activity of Some Oxazole and Thiazole Derivatives
International Journal of Pharmacy and Pharmaceutical Research (IJPPR) will give best paper award every year in the form of money along with certificate to support research activity of scholar ...
http://ijppr.humanjournals.com/synthesis-characterization-and-antimicrobial-activity-of-some-oxazole-and-thiazole-derivatives/
Thiazole derivatives - Patent # 4919706 - PatentGenius
Certain N-[(heterocyclic)aminocarbonyl]thiazolesulfonamides, such as N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-4-thiazolesulfonamide, are useful as herbicides and/or plant growth regulants.
http://www.patentgenius.com/patent/4919706.html
Application # 2001/0000178. PYRIDYL SUBSTITUTED THIAZOLES - Patents.com
Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a
http://patents.com/us-20010000178.html
一种含有2-吡啶基噻吩的噻唑小分子的合成及其对HSO3-的识别-Synthesis of Thiazole Small Molecule Containing 2-Pyridylthiophene and Its Recognition to HSO3
以1-乙基碘化-2-甲基苯并噻唑为原料,合成一种新的噻唑衍生物(化合物1),并通过1H NMR、MS谱表征了其结构。以检测水溶液中HSO3-为目的,利用紫外-可见光谱研究了Cl-,Br-,I-,NO3-,H2PO4-,CO32-,HCO3-,ClO4-,SO42-,Ac-,HS-,HSO3-等常见阴离子对化合物1光谱的影响。研究表明：化合物1对HSO3-具有响应时间快、检测限低(0.25 μmol.L-1)等特点；通过比较发现,化合物1对HS￣的检测限2.4 μmol.L-1,但需较长的反应时间。因此,在短时间、低浓度下,HS-对HSO3-的识别无明显干扰,化合物1可用于快速选择性检测HSO3-。;A new thiazole
http://znzk.scuec.edu.cn/ch/reader/view_abstract.aspx?flag=2&file_no=201710110000001&journal_id=znmzdxxbzr
Plus itPlus it
5745 Interactions between dual Bcr/Abl and Src inhibitor dasatinib and MEK1/2 inhibitors have been examined in CML cell lines and primary specimens, including those resistant to imatinib mesylate. Co-treatment of K562 or LAMA cells with marginally toxic concentrations of the MEK1/2 inhibitors PD184352 or U0126 and extremely low concentrations of dasatinib (e.g., sub-nanomolar) synergistically potentiated mitochondrial damage, caspase activation, and apoptosis. Similar interactions were observed in CD34+ cells from a CML patient-derived but not in normal human CD34+ bone marrow cells. These interactions were associated with multiple perturbations in survival signaling pathways, including inactivation of Bcr/Abl, STAT5, ERK1/2, down-regulation of Bcl-xL, Mcl-1, and dephosphorylation/activation of BIM. These perturbations were also associated with BAX and BAK translocation, resulting in activation of caspases as well as mitochondrial dysfunction. BIM knockdown by shRNA suppressed both BAX and BAK ...
http://cancerres.aacrjournals.org/content/67/9_Supplement/5745
5-ethyl-4-methyl-2-nonyl-3-thiazoline, cis5-ethyl-4-methyl-2-nonyl-3-thiazoline, cis
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/inchi/InChI%3D1S/C15H29NS/c1-4-6-7-8-9-10-11-12-15-16-13
A Phase II Study of Biological Response to Dasatinib Treatment in Patients with Acral Lentiginous, or Mucosal MelanomaA Phase II Study of Biological Response to Dasatinib Treatment in Patients with Acral Lentiginous, or Mucosal Melanoma
The goal of this clinical research study is to compare how the drug Sprycel (dasatinib) can help to control the tumor in patients whose tumor has a gene abnormality known as a
https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.ID2009-0447.html
Masitinib (AB1010) | c-Kit Inhibitor | MedChemExpressMasitinib (AB1010) | c-Kit Inhibitor | MedChemExpress
Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity. - Mechanism of Action & Protocol.
https://www.medchemexpress.com/Masitinib.html
Masitinib ( AB1010)Masitinib ( AB1010)
immune Uncategorized Col4a2, Masitinib ( AB1010) interactions where the biological aftereffect of an publicity depends upon an individuals genotype are widely held to become ubiquitous-and rightly thus considering epidemiologists have got long abandoned the paradigm of ascribing disease to either character or nurture (if indeed they ever considered etiology in unifactoral conditions) and today seek to comprehend the joint actions of both character and nurture. gene-environment connections in individual observational research stands in sharpened contrast towards the wide-spread proof for gene-environment relationship from experimental research in model microorganisms (2). This discrepancy is certainly a puzzle. Masitinib ( AB1010) Will there be something fundamentally different about the biology of individual complicated attributes? Are there limitations to how gene-environment interactions have been analyzed in humans? Or both? Stenzel et al. (3) discuss two important methodological ...
https://www.immune-source.com/tag/masitinib-ab1010/
RCSB PDB - 1ADF: CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE...RCSB PDB - 1ADF: CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE...
1ADF: Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1ADF
RCSB PDB - 1ADG: CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE...RCSB PDB - 1ADG: CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE...
1ADG: Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1ADG
CAS 87-69-4 products price,suppliersCAS 87-69-4 products price,suppliers
Look for 4-Bromo-1,3-thiazole-2,5-dicarbaldehyde (cas 87-69-4) prices, manufacturers, suppliers, exporters start with Guidechem!Global mass 4-Bromo-1,3-thiazole-2,5-dicarbaldehyde supplier for your selection.
https://www.guidechem.com/cas/87-69-4.html
Dasatinib thwarts brain cancer metastasis after bevacizumab use - ONADasatinib thwarts brain cancer metastasis after bevacizumab use - ONA
Combining the antiangiogenic bevacizumab with the kinase inhibitor dasatinib stopped glioblastoma metastasis after shrinking the tumors.
https://www.oncologynurseadvisor.com/web-exclusives/dasatinib-thwarts-brain-cancer-metastasis-after-bevacizumab-use/article/282198/
Does Dasatinib Improve Outcomes and Tolerability in Patients with Chro by Brian MerusiDoes Dasatinib Improve Outcomes and Tolerability in Patients with Chro by Brian Merusi
Objective: The objective of this selective EBM review is to determine whether or not dasatinib improves outcomes and tolerability in patients with chronic myeloid leukemia as compared to imatinib. Study Design: Review of three English language, non-blinded randomized controlled trials from 2009, 2010, and 2010. Data Sources: Randomized, controlled, non-blinded clinical trials comparing dasatinib to imatinib or comparing dasatinib once daily vs dasatinib twice daily, found using the PubMed database. Outcomes measured: Overall survival and progression-free survival were measured at one and two years after initiation of therapy. Safety profiles and incidence of adverse effects were also measured. This is graded on a scale of 1 to 4, from lowest in severity to highest in severity. Additionally, adverse effects were noted as hematologic (neutropenia, anemia, thrombocytopenia) or nonhematologic (fluid retention, diarrhea, vomiting, fever). Results: When comparing dasatinib to imatinib, both drugs provided
https://digitalcommons.pcom.edu/pa_systematic_reviews/52/
Thiazoles | Harvard Catalyst Profiles | Harvard CatalystThiazoles | Harvard Catalyst Profiles | Harvard Catalyst
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial. Trials. 2021 Jan 04; 22(1):3 ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Thiazoles
Induced Phenotypic Resistance to an Antimetabolite | ScienceInduced Phenotypic Resistance to an Antimetabolite | Science
Resistance to bacteriostasis by 2-thiazole alanine develops rapidly; however, such resistance is lost during growth in the absence of the analog. This induced resistance is accompanied by increased formation of an enzyme sensitive to 2-thiazole alanine. Maintenance of the elevated enzyme levels in growing cells, like resistance, requires the presence of the analog. ...
http://science.sciencemag.org/content/131/3411/1449
ECMDB: 4-Methyl-5-(2-phosphoethyl)-thiazole (ECMDB20094) (M2MDB000942)
Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). EcoCyc: a comprehensive database of Escherichia coli biology. Nucleic Acids Res 39:D583-D590. Pubmed: 21097882 ...
http://ecmdb.ca/compounds/ECMDB20094
Thiazole, 5-ethyl-2-methylThiazole, 5-ethyl-2-methyl
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/cbook.cgi?ID=C19961525&Units=CAL&Mask=2000&Type=KOVATS-RI-POLAR-ISOTHERMAL
Ziprasidone treatment
Ziprasidone treatment ziprasidone 20 mg order generic online 120 amount of packaging only $96. Ziprasidone treatment non a prescription.
https://tennistopic.com/ziprasidone-antidepressant-2605127/ziprasidone-treatment
N-(2-Ethylpyrimidin-4-yl)-1,3-thiazol-2-amine | C9H10N4S - PubChemN-(2-Ethylpyrimidin-4-yl)-1,3-thiazol-2-amine | C9H10N4S - PubChem
N-(2-Ethylpyrimidin-4-yl)-1,3-thiazol-2-amine | C9H10N4S | CID 88854415 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/N-_2-Ethylpyrimidin-4-yl_-1_3-thiazol-2-amine
2634-33-5, Ziprasidone, Ziprasidone hydrochloride, Ziprasidone Mesylate, Intermediate, Manufacturer, Supplier, India, China
Manus Aktteva Biopharma LLP, a global supplier of 1,2-Benzisothiazolin-3-one (CAS No.: 2634-33-5), 2634-33-5 offers for your requirements of RND, evaluation, pilots and commercial along with supportive technical package required for evaluation.
http://www.manusaktteva.com/intermediate/2634-33-5
The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal...
BACKGROUND: The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from being a fatal disorder to becoming a chronic disease. Due to the probable long lasting treatment with tyrosine-kinase inhibitors (TKIs), the knowledge of their effects on normal cells is of pivotal importance.. DESIGN AND METHODS:. We investigated the effects of dasatinib treatment on human bone marrow-derived mesenchymal stromal cells (MSCs).. RESULTS:. Our findings demonstrate, for the first time, that dasatinib induces MSCs adipocytic differentiation. Particularly, when the TKI is added to the medium inducing osteogenic differentiation, a high MSCs percentage acquires adipocytic morphology and overexpresses adipocytic specific genes, including PPARγ, CEBPα, LPL and SREBP1c. Dasatinib also inhibits the activity of alkaline phosphatase, an osteogenic marker, and remarkably reduces matrix mineralization. The increase of PPARγ is ...
https://iris.unicampania.it/handle/11591/187709
Thiazole: A Privileged Motif in Marine Natural Products | Bentham ScienceThiazole: A Privileged Motif in Marine Natural Products | Bentham Science
Title:Thiazole: A Privileged Motif in Marine Natural Products. VOLUME: 16 ISSUE: 1. Author(s):Sunil Kumar* and Ranjana Aggarwal. Affiliation:Department of Chemistry, Kurukshetra University, Kurukshetra-136119, Department of Chemistry, Kurukshetra University, Kurukshetra-136119. Keywords:Marine natural products, thiazoles, alkaloids, cytotoxic activity, privileged, secondary metabolite.. Abstract:Marine natural products have proven to be a rich source of drugs and drug leads. These natural products are secondary metabolites and show biological activity against bacteria, fungi and viruses. Natural products containing thiazole ring occur often in marine sources. They exhibit diverse and remarkable biological activities, including antitumor, antibacterial, anti-inflammatory and cytotoxic activities, to name a few. This review surveys the natural thiazole derivatives that have been isolated from marine microorganisms, with emphasis on biological implications in last three decades.. ...
https://www.eurekaselect.com/161231/article
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)<...
TY - JOUR. T1 - An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). AU - Lehmann, Jürgen M.. AU - Moore, Linda B.. AU - Smith-Oliver, Tracey A.. AU - Wilkison, William O.. AU - Willson, Timothy M.. AU - Kliewer, Steven A.. PY - 1995/6/2. Y1 - 1995/6/2. N2 - Thiazolidinedione derivatives are antidiabetic agents that increase the insulin sensitivity of target tissues in animal models of non-insulin- dependent diabetes mellitus. In vitro, thiazolidinediones promote adipocyte differentiation of preadipocyte and mesenchymal stem cell lines; however, the molecular basis for this adipogenic effect has remained unclear. Here, we report that thiazolidinediones are potent and selective activators of peroxisome proliferator-activated receptor γ (PPARγ), a member of the nuclear receptor superfamily recently shown to function in adipogenesis. The most potent of these agents, BRL49653, binds to PPARγ with a K(d) of approximately 40 nM. ...
https://utsouthwestern.pure.elsevier.com/en/publications/an-antidiabetic-thiazolidinedione-is-a-high-affinity-ligand-for-p
A Density Function Theory Based Quantitative Structure Activity Relationships Study of Thiazoline Derivatives as Anticancer...A Density Function Theory Based Quantitative Structure Activity Relationships Study of Thiazoline Derivatives as Anticancer...
The Quantitative Structure-Activity Relationship of a series of novel Thiazoline derivatives with anticancer activity has been studied by using the density functional theory by B3LYP/ 6-31G. Descriptors of quantum mechanics of 21 thiazoline derivatives with known activity were obtained. Multiple linear regressions were employed to model the relationships between molecular descriptors and biological activity of molecules using stepwise method. The most model shows not only significant statistical quality, but also predictive ability, with the square of adjusted correlation coefficient (R2=0.945) and standard error (SE=0.586). We find that the anticancer activity expressed that as half maximal inhibitory concentration (IC50), closely relates to the highest occupied molecular orbital, dipole moment, softness, hardness, ionization energy, electron affinity. Accordingly can be offered a quantitative model, and interpret the activity of the compounds relying on the multivariate statistical analysis. This
http://ijac.journals.pnu.ac.ir/article_2178_116.html
CAS No.49790-72-9,Benzothiazole, 2-[[(5-nitro-2-furanyl)methyl]thio]- SuppliersCAS No.49790-72-9,Benzothiazole, 2-[[(5-nitro-2-furanyl)methyl]thio]- Suppliers
Find quality suppliers and manufacturers of 49790-72-9(Benzothiazole, 2-[[(5-nitro-2-furanyl)methyl]thio]-) for price inquiry. where to buy 49790-72-9(Benzothiazole, 2-[[(5-nitro-2-furanyl)methyl]thio]-).Also offer free database of 49790-72-9(Benzothiazole, 2-[[(5-nitro-2-furanyl)methyl]thio]-) including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, solution etc.
http://www.lookchem.com/cas-497/49790-72-9.html
2-Amino-6-fluorobenzothiazole (CAS 348-40-3) Market Research Report 20182-Amino-6-fluorobenzothiazole (CAS 348-40-3) Market Research Report 2018
2-Amino-6-fluorobenzothiazole (CAS 348-40-3) Market Research Report 2018 aims at providing comprehensive data on 2-amino-6-fluorobenzothiazole market
https://marketpublishers.com/report/industry/chemicals_petrochemicals/cbindex_348-40-3_market_research_report.html
BENZO[D]THIAZOLE,2-(PYRIDIN-4-YL)-, CasNo.2295-38-7 Angene International Limited United KingdomBENZO[D]THIAZOLE,2-(PYRIDIN-4-YL)-, CasNo.2295-38-7 Angene International Limited United Kingdom
BENZO[D]THIAZOLE,2-(PYRIDIN-4-YL)- 2295-38-7 Suppliers,provide BENZO[D]THIAZOLE,2-(PYRIDIN-4-YL)- 2295-38-7 product and the products related with United Kingdom BENZO[D]THIAZOLE,2-(PYRIDIN-4-YL)- 2295-38-7 Angene International Limited United Kingdom
https://angene.lookchem.com/products/CasNo-2295-38-7-BENZO-D-THIAZOLE-2--PYRIDIN-4-YL---6434624.html
Benzothiazole, 4-nitro- (6CI,7CI,8CI,9CI) (CAS 2942-08-7) Market Research Report 2018Benzothiazole, 4-nitro- (6CI,7CI,8CI,9CI) (CAS 2942-08-7) Market Research Report 2018
The report generally describes benzothiazole, 4-nitro- (6ci,7ci,8ci,9ci), examines its uses, production methods, patents. Benzothiazole, 4-nitro- (6CI,7CI,8CI,9CI)
https://marketpublishers.com/report/industry/chemicals_petrochemicals/benzothiazole_4-nitro-_6ci_7ci_8ci_9ci_2942-08-7_market_research_report.html
Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts | BMC Research Notes | Full TextDasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts | BMC Research Notes | Full Text
In this study, we compared the effects of the Src inhibitor dasatinib on the urothelial cancer cell line RT112 and its gemcitabine-resistant sub-line RT112rGEMCI20 in cell culture and in an orthotopic bladder cancer xenograft model in mice.. In cell culture, both cell lines displayed similar growth kinetics. Dasatinib inhibited Src phosphorylation in RT112 and RT112rGEMCI20 cells at low nanomolar concentrations similar to those that had already been described to affect Src phosphorylation [9]. While dasatinib had previously been shown to interfere with the phosphorylation of Akt (Thr308 and Ser473) in squamous cell lung cancer [22], we only detected inhibition of phosphorylation of Akt (Thr308). The reasons for this may be the consequence of cell type-specific differences between the investigated models. Although dasatinib exerted similar effects on Src signaling in RT112 and RT112rGEMCI20 cells, its effects on cell viability differed between the two cell lines. The effective concentrations of ...
https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-016-2256-3
Meloxicam En France - Expédition rapide - BTC accepté - IPolicyPlanet
Ordonner Mobic Meloxicam En Ligne, Acheter Meloxicam Bon Marché, Acheter Meloxicam Au Senegal, Comment Acheter Du Meloxicam Sur Le Net, Acheter Meloxicam Thailande, Acheter Mobic Pfizer France, Achat Meloxicam Original, Commander Mobic 7.5 mg Le Moins Cher, Forum Ou Acheter Mobic En Ligne, Site De Confiance Pour Acheter Mobic, Ou Acheter Du Mobic Pour Femme En France, Commander Meloxicam Generic, Ordonner Générique 7.5 mg Mobic Japon, Acheter Mobic Au Senegal, Acheter Mobic Generique France, Achat Générique Meloxicam Le Portugal, acheté Meloxicam à prix réduit, Achetez Mobic 7.5 mg Bas Prix Sans Ordonnance, Achat Mobic 7.5 mg Moins Cher, Buy Meloxicam Over Internet, Meloxicam Pas Cher Paypal, Mobic 7.5 mg Vente Générique, acheté Mobic à prix réduit, Achetez Générique Mobic Singapour, Achat Générique Mobic Meloxicam France, Acheté Générique Mobic 7.5 mg Lille, Acheté Générique Mobic Strasbourg, Mobic Meloxicam Passer La Commande, Pharmacie En Ligne Mobic Generique, Achat ...
http://ipolicyplanet.com/2017/06/13/meloxicam-en-france-expedition-rapide-btc-accepte/
Syntheses and antibacterial activity of testosterone succinate-vitamin B|inf|1|/inf| conjugate<...Syntheses and antibacterial activity of testosterone succinate-vitamin B|inf|1|/inf| conjugate<...
TY - JOUR. T1 - Syntheses and antibacterial activity of testosterone succinate-vitamin B1 conjugate. AU - Figueroa-Valverde, L.. AU - Díaz-Cedillo, F.. AU - Camacho-Luis, A.. AU - Lopez-Ramos, M.. PY - 2010/8/20. Y1 - 2010/8/20. N2 - In this study, a straight forward route for the synthesis of testosterone succinate-vitamin B1 conjugate and their antibacterial activities on S. aureus, E. coli and K. pneumoniae are reported. This first step was achieved by reacting 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5- (2-hydroxyethyl)-4-methylthiazolium chloride (vitamin B1) with testosterone- succinate resulting in amide bond formation. The results showed that the 1H NMR spectra of the testosterone succinate-vitamin B1 conjugate shows upfield shifts at 0.80 and 1.19 ppm for methyls present in the heterocyles rings at 3.18 and 3.90 ppm for methylenes of the hydroxietilen moiety bonded to thiazol ring. The hydrogens of the methylene between the pyrimidine and thiazol rings appears at 5.68 ppm. In ...
https://ipn.elsevierpure.com/en/publications/syntheses-and-antibacterial-activity-of-testosterone-succinate-vi
Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer | Molecular...Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer | Molecular...
Here, we describe a large-scale mass spectrometry-based proteomics approach to delineate phosphoproteome responses to the MEK inhibitor selumetinib in the context of KRAS-mutant lung cancer. Previous studies showed global phosphoproteome responses to MEK and RAF inhibition in the context of BRAF-mutant melanoma (48, 49); to our knowledge, this study is the first global phosphoproteomics approach that addresses how KRAS-mutant lung cancer cells respond to pharmacologic MEK inhibition. Importantly, we demonstrate widespread increases in protein phosphorylation following treatment with a MEK inhibitor, which at first glance seems counterintuitive. However, this result is consistent with other observations that kinase inhibitors can lead to increased phosphorylation of some substrate proteins. Previously, we revealed TBK1 knockdown leads to increased phosphorylation of EGFR, MET, and their downstream ERK→Jun, Myc in KRAS-mutant lung cancer cells (23). The tyrosine kinase inhibitor dasatinib ...
http://mcr.aacrjournals.org/content/14/10/1019.full?ijkey=o28gQik1FnrpQ&keytype=ref&siteid=aacrjnls%3Futm_source%3D150506&utm_medium=landing10&utm_campaign=AMMR
Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies<...
TY - JOUR. T1 - Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies. AU - Su, Yi. AU - Flores, Shaney. AU - Wang, Guoqiao. AU - Hornbeck, Russ C.. AU - Speidel, Benjamin. AU - Joseph-Mathurin, Nelly. AU - Vlassenko, Andrei G.. AU - Gordon, Brian A.. AU - Koeppe, Robert A.. AU - Klunk, William E.. AU - Jack, Clifford R.. AU - Farlow, Martin R.. AU - Salloway, Stephen. AU - Snider, Barbara J.. AU - Berman, Sarah B.. AU - Roberson, Erik D.. AU - Brosch, Jared. AU - Jimenez-Velazques, Ivonne. AU - van Dyck, Christopher H.. AU - Galasko, Douglas. AU - Yuan, Shauna H.. AU - Jayadev, Suman. AU - Honig, Lawrence S.. AU - Gauthier, Serge. AU - Hsiung, Ging Yuek R.. AU - Masellis, Mario. AU - Brooks, William S.. AU - Fulham, Michael. AU - Clarnette, Roger. AU - Masters, Colin L.. AU - Wallon, David. AU - Hannequin, Didier. AU - Dubois, Bruno. AU - Pariente, Jeremie. AU - Sanchez-Valle, Raquel. AU - Mummery, Catherine. AU - Ringman, John M.. AU - Bottlaender, ...
https://mayoclinic.pure.elsevier.com/en/publications/comparison-of-pittsburgh-compound-b-and-florbetapir-in-cross-sect
DDW How to Buy Used or Surplus Circuit Breakers | Spy BotDDW How to Buy Used or Surplus Circuit Breakers | Spy Bot
For homes or businesses trying to cut costs, used circuit breakers may be an option for their electrical needs. You can visit several online stores that carry all sorts of brands of used circuit breakers. Finding a used circuit breaker can also be useful in locating obsolete or outdate breakers. Many companies only sell used circuit breakers that have been tested for quality and safety. Because used circuit breakers are usually old, it is necessary to test them prior to purchase or using them. Testing used circuit breakers is essential for safety as well as for functional reasons. In older used breakers, the naked eye simply cannot determine if the contacts are corroded. If the contacts are indeed corroded, your circuit breaker may not function properly or safely. Most electricians recommend not to use used circuit breakers to ensure your safety, because prices on new circuit breakers are generally reasonable.. Sometime a company may have too many circuit breakers or breakers that have become ...
https://spy-bot.net/ddw-how-to-buy-used-or-surplus-circuit-breakers/
Benzothiazole derivatives, processes for their preparation and pharmaceutical compositions containing these compounds -...
Benzothiazole derivatives corresponding to the general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent, independently of one another, a hydrogen atom, a halogen atom, a linear C.sub.1 -C.sub.3 -alkyl group or a linear C.sub.1 -C.sub.3 -alkoxy group, R.sup.5 represents a hydrogen atom or a linear C.sub.1 -C.sub.3 -alkyl group, R.sup.6 represents a hydrogen atom, and R.sup.7 represents a formyl group, a carbalkoxy group of the formula ##STR2## wherein R.sup.8 denotes a linear or branch chained C.sub.1 -C.sub.4 -alkyl group, or it represents an acyl group of the formula ##STR3## wherein R.sup.9 denotes a linear C.sub.1 -C.sub.3 -alkyl group, or R.sup.6 and R.sup.7 together represent the group ##STR4## wherein R.sup.10 and R.sup.11 represent, independently of one another, a hydrogen atom or a linear C.sub.1 -C.sub.6 -alkyl group or R.sup.6 and R.sup.7 represent the group ##STR5## wherein R.sup.12 and R.sup
http://www.patentgenius.com/patent/4732986.html
Synthesis and structural studies of novel benzothiazole derivative and evaluation of their antimicrobial activity| AbstractSynthesis and structural studies of novel benzothiazole derivative and evaluation of their antimicrobial activity| Abstract
Benzothiazole are important group of compounds reported to have various biological activities and hence the present study was undertaken in order to s..
http://www.derpharmachemica.com/abstract/synthesis-and-structural-studies-of-novel-benzothiazole-derivativernand-evaluation-of-their-antimicrobial-activity-11052.html
Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof - Miller, Duane D.Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof - Miller, Duane D.
Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides according to formulae (I) and (II) are disclosed |chemistry id=CHEM-US-00001 num=1||img id=
http://www.freepatentsonline.com/y2006/0040998.html
Browsing by Keywords ThiazolidineBrowsing by Keywords Thiazolidine
The forward chemogenomics strategy allowed us to identify a potent cytotoxic thiazolidine compound as an apoptosis-inducing agent. Chemical structures were designed around a thiazolidine ring, a structure already noted for ...
http://repository.bilkent.edu.tr/browse?type=subject&value=Thiazolidine
Synthesis of 2,3-Dihydroimidazo[2,1-b]thiazole Derivatives via Cyclization of N-Allylimidazoline-2-thiones - Zurich Open...Synthesis of 2,3-Dihydroimidazo[2,1-b]thiazole Derivatives via Cyclization of N-Allylimidazoline-2-thiones - Zurich Open...
TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents ...
http://www.zora.uzh.ch/id/eprint/39535/
film of 3,9-di(9H-carbazol-9-yl)benzo-[d]benzo[4,5]imidazo[2,1-b]thiazole doped with 10-(4-(4,6-diphenyl-1,3,5-triazin-2-yl...film of 3,9-di(9H-carbazol-9-yl)benzo-[d]benzo[4,5]imidazo[2,1-b]thiazole doped with 10-(4-(4,6-diphenyl-1,3,5-triazin-2-yl...
Page contains details about film of 3,9-di(9H-carbazol-9-yl)benzo-[d]benzo[4,5]imidazo[2,1-b]thiazole doped with 10-(4-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-9,9-diphenyl-9,10-dihydroacridine . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-M8044813
CARBOXY OXAZOLE OR THIAZOLE COMPOUNDS AS DGAT- 1 INHIBITORS USEFUL FOR THE TREATMENT OF OBESITY - Patent applicationCARBOXY OXAZOLE OR THIAZOLE COMPOUNDS AS DGAT- 1 INHIBITORS USEFUL FOR THE TREATMENT OF OBESITY - Patent application
0114] Compounds of formula (I): [0115] Methyl 3-methyl-2-(5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)oxazole-2-ca- rboxamido)butanoate, [0116] 3-Methyl-2-(5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)oxazole-2-ca- rboxamido)butanoic acid, [0117] Methyl 2-(5-(4-(3-(2-chlorophenyl)ureido)phenyl)oxazole-2-carboxamido)-3-methylb- utanoate, [0118] 2-(5-(4-(3-(2-Chlorophenyl)ureido)phenyl)oxazole-2-carboxamido)-3-methylb- utanoic acid, [0119] Methyl 2-(5-(4-(3-(3,4-dimethylphenyl)ureido)phenyl)oxazole-2-carboxamido)-3-met- hylbutanoate, [0120] 2-(5-(4-(3-(3,4-dimethylphenyl)ureido)phenyl)oxazole-2-carboxamido)-3-met- hylbutanoic acid, [0121] Methyl 2-(5-(4-(3-(4-chloro-2-phenoxyphenyl)ureido)phenyl)oxazole-2-carboxamido)- -3-methylbutanoate, [0122] 2-(5-(4-(3-(4-chloro-2-phenoxyphenyl)ureido)phenyl)oxazole-2-carboxamido)- -3-methylbutanoic acid, [0123] Methyl 3-methyl-2-(5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)thiazole-2-c- arboxamido)butanoate, [0124] ...
http://www.patentsencyclopedia.com/app/20120214854
A Novel and Expedient Approach to New Thiazoles, Thiazolo3,2-apyridines, Dihydrothiophenes, and Hydrazones Incorporating...
A Novel and Expedient Approach to New Thiazoles, Thiazolo3,2-apyridines, Dihydrothiophenes, and Hydrazones Incorporating Thieno2,3-bthiophene Moiety. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/jun5/149743144414-A-Novel-and-Expedient-Approach-to-New-Thiazoles-Thiazolo32-apyridines-Dihydrothiophenes-and-Hydrazones-Incorporating-Thieno23-bthiophene-Moiety.php
Meloxicam Sulfa Allergy - Bula Do Meloxicam 2 MgMeloxicam Sulfa Allergy - Bula Do Meloxicam 2 Mg
Meloxicam tablets for dogs in india, meloxicam generico 15 mg, picture of generic meloxicam, para que sirve meloxicam con metocarbamol, meloxicam 7 5 mg para que serve, meloxicam for cats for sale, meloxicam y metocarbamol efectos secundarios
http://www.delpiano.com/bestsellers/index.php/meloxicam-sulfa-allergy-28dn
Plus itPlus it
This study shows for the first time that the novel thiazole antibiotic thiostrepton selectively induces cell death in breast cancer cells through the down-regulation of FOXM1 expression. Furthermore, thiostrepton treatment, accompanied by a loss of FOXM1 expression, results in a reduction in the proliferation, invasiveness, and transformation ability of breast cells. Critically, thiostrepton has no affect on the proliferation of nontransformed breast epithelial cells.. Thiostrepton has been identified previously as an anticancer agent in a study of thiazole antibiotics and derivatives (16). We sought to identify the mechanism by which thiostrepton may induce cell death in breast cancer cells and determined the expression level and activity of a series of cell fate regulators in response to thiostrepton treatment. No change was observed in the phosphorylation status of the prosurvival factors Akt and ERK, whereas phosphorylation of FOXO3a, which we have reported previously as a critical mediator ...
https://mct.aacrjournals.org/content/7/7/2022
Structure revision of N-mercapto-4-formylcarbostyril produced by Pseudomonas fluorescens G308 to 2-(2-hydroxyphenyl)thiazole-4...
An antibiotic substance isolated from Pseudomonas fluorescens strain G308 was earlier assigned the structure of N-mercapto-4-formylcarbosty...
https://orgc.research.vub.be/structure-revision-of-n-mercapto-4-formylcarbostyril-produced-by-pseudomonas-fluorescens-g308-to-2-2
ACTIVE INGREDIENT FORMULATIONS CONTAINING 2-THIAZOLE-4YL-1H-BENZOIMIDAZOL (THIABEN-DAZOLE OR TBZ) FOR THE PRODUCTION OF WPC -...ACTIVE INGREDIENT FORMULATIONS CONTAINING 2-THIAZOLE-4YL-1H-BENZOIMIDAZOL (THIABEN-DAZOLE OR TBZ) FOR THE PRODUCTION OF WPC -...
0003]One component of the driving force of this market trend is and was certainly the assumption that, owing to their proportion of plastic, WPC are resistant to attack by fungi. However, only shortly after the market launch of WPC for the outdoor sector, reports of fungal growth of naturally weathered WPC appeared (P. I. Morris and P. Cooper, Forest Products Journal, 1998, 48(1), 86-88) and subsequent investigations in the laboratory clearly showed the susceptibility of WPC to fungal growth (e.g. P. E. Laks, Wood Design Focus, 2000, 11(4), 7.14; M. Mankowski and J. J. Morrell, Wood and Fiber Science, 2000, 32(3), 340-345; N. M. Stark et al., Journal of Applied Polymer Science, 2003, 90(10), 2609-2617). In particular, wood-discolouring fungi and fungi causing soft rot, such as, for example, Ascomycetes and Deuteromycetes, play an important role here. In addition to said fungi, wood-destroying fungi, such as, for example, Basidiomycetes, can also attack and destroy WPC. Further studies on ...
http://www.patentsencyclopedia.com/app/20100330185
AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thalianaAtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana
Thiamine (vitamin B(1)) is an essential compound for organisms. It contains a pyrimidine ring structure and a thiazole ring structure. These two moieties of thiamine are synthesized independently and then coupled together. Here we report the molecular characterization of AtTHIC, which is involved in …
https://pubmed.ncbi.nlm.nih.gov/18332905/?dopt=Abstract
Dasatinib 302962-49-8, China Dasatinib 302962-49-8 Manufacturers, China Dasatinib 302962-49-8 Suppliers
We,China Dasatinib 302962-49-8 Suppliers and China Dasatinib 302962-49-8 Manufacturers, provide Dasatinib 302962-49-8 product and the products related with China Dasatinib 302962-49-8
http://chemnet.com/ChinaSuppliers/53271/Dasatinib--2257707.html
Dasatinib 302962-49-8, China Dasatinib 302962-49-8 Manufacturers, China Dasatinib 302962-49-8 Suppliers - princechem
We,China Dasatinib 302962-49-8 Suppliers and China Dasatinib 302962-49-8 Manufacturers, provide Dasatinib 302962-49-8 product and the products related with China Dasatinib 302962-49-8 - princechem
http://chemnet.com/ChinaSuppliers/16771/Dasatinib--2144486.html
Heterocyclic Benzothiazoles Supplier & Distributors | ApolloHeterocyclic Benzothiazoles Supplier & Distributors | Apollo
Heterocyclic Benzothiazoles Manufacture, Bulk Supply & Global Distributors. View & Buy from our full range of Heterocyclic Benzothiazoles | Apollo Scientific
https://store.apolloscientific.co.uk/category/chemicals/heterocyclic-building-blocks/heterocyclic-benzothiazoles
Marine Drugs | Free Full-Text | Thiopeptide Antibiotics: Retrospective and Recent Advances | HTMLMarine Drugs | Free Full-Text | Thiopeptide Antibiotics: Retrospective and Recent Advances | HTML
Thiopeptides, or thiazolyl peptides, are a relatively new family of antibiotics that already counts with more than one hundred different entities. Although they are mainly isolated from soil bacteria, during the last decade, new members have been isolated from marine samples. Far from being limited to their innate antibacterial activity, thiopeptides have been found to possess a wide range of biological properties, including anticancer, antiplasmodial, immunosuppressive, etc. In spite of their ribosomal origin, these highly posttranslationally processed peptides have posed a fascinating synthetic challenge, prompting the development of various methodologies and strategies. Regardless of their limited solubility, intensive investigations are bringing thiopeptide derivatives closer to the clinic, where they are likely to show their veritable therapeutic potential.
http://www.mdpi.com/1660-3397/12/1/317/htm
Polbase - Structure of polymerase: Co(III)bleomycinB2 bithiazole/C-terminal tail domain bound to d(ATTTAGTTAACTAAAT) complexed...
Polymerase structure: Co(III)bleomycinB2 bithiazole/C-terminal tail domain bound to d(ATTTAGTTAACTAAAT) complexed with MMLV RT catalytic fragment ( PDBid: 2R2U)
https://polbase.neb.com/structures/415-co-iii-bleomycinb2-bithiazole-c-terminal-tail-domain-bound-to-d-atttagttaactaaat-complexed-with-mmlv-rt-catalytic-fragment
Publishers of academic thesis & dissertations. Free search & preview. PDF downloads. Instant access to paperback & ebook...Publishers of academic thesis & dissertations. Free search & preview. PDF downloads. Instant access to paperback & ebook...
KIT inhibition with dasatinib represents a promising approach to targeted therapy in t(8;21) acute myeloid leukemia (AML) and clinical trials are currently evaluating its clinical relevance. However, data on continuous long-term dasatinib exposure of AML cells are limited and the potential effects on KIT inhibition and dasatinib sensitivity are unexplored. Treatment-related resistance ultimately limits clinical efficacy of tyrosine kinase inhibitors (TKI), which could similarly apply to dasatinib in t(8;21) AML. In this study, we used the dasatinib-sensitive KITmut t(8;21) AML cell line Kasumi-1 to model, in a confined and control- lable way, molecular effects upon continuous dasatinib treatment. Long-term dasatinib exposure at clinically relevant levels resulted in markedly decreased drug-sensitivity of KITmut t(8;21) AML cells. Notably, all dasatinib-resistant clones lacked secondary KIT-mutations. Instead, persistent growth correlated with alterations in KIT expression levelsdthat is, either KIT
http://www.dissertation.com/abstracts/1116838
elisa kits manufacturer - Protocols for Western Blot and Rabbit Poly-clonal antibodies anti-human proteinselisa kits manufacturer - Protocols for Western Blot and Rabbit Poly-clonal antibodies anti-human proteins
Two novel isosteric conjugates of guanidiniocarbonyl-pyrrole and 6-bromo-TO (thiazole orange) had been ready, differing solely in linker connectivity to cyanine (benzothiazole nitrogen vs. quinoline nitrogen). The quinoline analog was considerably extra vulnerable to aggregation in an aqueous medium, which resulted in induced round dichroism (ICD; λ = 450-550 nm) recognition between A-T(U) and G-C basepair …. Fluorimetric and CD Recognition between Various ds-DNA/RNA Depends on a Cyanine Connectivity in Cyanine-guanidiniocarbonyl-pyrrole Conjugate Read More ». ...
https://westernblotinfo.com/tag/elisa-kits-manufacturer/
Antibodies - Protocols for Western Blot and Rabbit Poly-clonal antibodies anti-human proteinsAntibodies - Protocols for Western Blot and Rabbit Poly-clonal antibodies anti-human proteins
Two novel isosteric conjugates of guanidiniocarbonyl-pyrrole and 6-bromo-TO (thiazole orange) had been ready, differing solely in linker connectivity to cyanine (benzothiazole nitrogen vs. quinoline nitrogen). The quinoline analog was considerably extra vulnerable to aggregation in an aqueous medium, which resulted in induced round dichroism (ICD; λ = 450-550 nm) recognition between A-T(U) and G-C basepair …. Fluorimetric and CD Recognition between Various ds-DNA/RNA Depends on a Cyanine Connectivity in Cyanine-guanidiniocarbonyl-pyrrole Conjugate Read More ». ...
https://westernblotinfo.com/category/antibodies/
Design, synthesis, biological evaluation and preliminary mechanism study of novel benzothiazole derivatives bearing indole...Design, synthesis, biological evaluation and preliminary mechanism study of novel benzothiazole derivatives bearing indole...
Sigma-Aldrich offers abstracts and full-text articles by [Junjie Ma, Guanglong Bao, Limei Wang, Wanting Li, Boxuan Xu, Baoquan Du, Jie Lv, Xin Zhai, Ping Gong].
https://www.sigmaaldrich.com/catalog/papers/25874341
ThiazoleThiazole
... , or 1,3-thiazole, is a heterocyclic compound that contains both sulfur and nitrogen. The term 'thiazole' also refers ... Thiazoles are structurally similar to imidazoles, with the thiazole sulfur replaced by nitrogen. Thiazole rings are planar and ... Thiazole itself is a pale yellow liquid with a pyridine-like odor and the molecular formula C3H3NS. The thiazole ring is ... Certain thiazoles can be accessed through application of the Herz reaction. Thiazoles are generally formed via reactions of ...
https://en.wikipedia.org/wiki/Thiazole
Thiazole tautomeraseThiazole tautomerase
... (EC 5.3.99.10, tenI (gene)) is an enzyme with systematic name 2-(2-carboxy-4-methylthiazol-5-yl)ethyl ... Thiazole+tautomerase at the US National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 5.3.99). ... Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP (June 2011). "A missing enzyme in thiamin thiazole ... ethyl phosphate The enzyme catalyses the irreversible aromatization of the thiazole moiety of 2-[(2R,5Z)-2-carboxy-4- ...
https://en.wikipedia.org/wiki/Thiazole_tautomerase
Thiazole synthaseThiazole synthase
... (EC 2.8.1.10, thiG (gene)) is an enzyme with systematic name 1-deoxy-D-xylulose 5-phosphate:thiol ... Thiazole+synthase at the US National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 2.8.1). ... Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP (June 2011). "A missing enzyme in thiamin thiazole ... Park JH, Dorrestein PC, Zhai H, Kinsland C, McLafferty FW, Begley TP (October 2003). "Biosynthesis of the thiazole moiety of ...
https://en.wikipedia.org/wiki/Thiazole_synthase
Cook-Heilbron thiazole synthesisCook-Heilbron thiazole synthesis
The Cook-Heilbron thiazole synthesis highlights the formation of 5-aminothiazoles through the chemical reaction of α- ... Thiazoles are found in a number of pharmacological compounds such as tiazofurin and dasatinib (antineoplastic agents), ... A couple of the compounds that were analysed for in vivo anti-cancer activity contained thiazole derivatives that had been ... Variation of substituents at the 2nd and 4th position of the thiazole is introduced by selecting different combinations of ...
https://en.wikipedia.org/wiki/Cook–Heilbron_thiazole_synthesis
ImidazothiazolesImidazothiazoles
Park, Jin-Hun; El-Gamal, Mohammed I.; Lee, Yong Sup; Oh, Chang-Hyun (2011-12-01). "New imidazo[2,1-b]thiazole derivatives: ... thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT6 Receptor Agonist". Journal of Medicinal ... thiazole moiety". European Journal of Medicinal Chemistry. 45 (1): 63-68. doi:10.1016/j.ejmech.2009.09.024. PMID 19939519. ... thiazole derivatives". European Journal of Medicinal Chemistry. 42 (3): 320-326. doi:10.1016/j.ejmech.2006.10.012. PMID ...
https://en.wikipedia.org/wiki/Imidazothiazoles
Sulfur dyeSulfur dye
They feature thiazoles, thiazone, thianthrene, and phenothiazonethioanthrone subunits. Being nonionic, sulfur dyes are ...
https://en.wikipedia.org/wiki/Sulfur_dye
SulfathiazoleSulfathiazole
v t e v t e (ECHA InfoCard ID from Wikidata, Drugs with no legal status, Thiazoles, Sulfonamide antibiotics, All stub articles ... Rouf A, Tanyeli C (June 2015). "Bioactive thiazole and benzothiazole derivatives". European Journal of Medicinal Chemistry. 97 ...
https://en.wikipedia.org/wiki/Sulfathiazole
OxazoleOxazole
Thiazole, an analog with the oxygen replaced by a sulfur. Benzoxazole, where the oxazole is fused to another aromatic ring. ... Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base; its conjugate acid has a pKa of 0.8, ... Oxazoles are not as abundant in biomolecules as the related thiazoles with oxygen replaced by a sulfur atom. With a pKa of 0.8 ...
https://en.wikipedia.org/wiki/Oxazole
BenzothiazoleBenzothiazole
... s consist of a 5-membered 1,3-thiazole ring fused to a benzene ring. The nine atoms of the bicycle and the ... Benzothiazoles are related to thiazoles, which lack the fused benzene ring. Benzoxazoles, which substitute an oxygen for the ... The heterocyclic core of the molecule is readily substituted at the unique methyne centre in the thiazole ring. It is a ... structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29, miscellaneous". EFSA ...
https://en.wikipedia.org/wiki/Benzothiazole
AccelerantAccelerant
The thiazoles are used for the vulcanization of thick articles, and as basic accelerator in EPDM compounds (ethylene-propylene- ... Another important group of primary accelerators is formed by the thiazoles. The two main products are mercaptobenzothiazole ( ...
https://en.wikipedia.org/wiki/Accelerant
SYBR SafeSYBR Safe
Thiazole orange does show toxicity at this dose. TO (Thiazole Orange) SYBR Green I SYBR Green II SYBR Gold YO (Oxazole Yellow) ... Thiazole Orange has been shown to be three to four times less mutagenic than ethidium bromide whereas SYBR Safe is four to five ... Evenson WE; Boden LM; Muzikar KA; O'Leary DJ (2012). "1H and 13C NMR Assignments for the Cyanine Dyes SYBR Safe and Thiazole ... SYBR Safe has a very similar structure to thiazole orange, which has a methyl group attached to the charged nitrogen, whereas ...
https://en.wikipedia.org/wiki/SYBR_Safe
5-HT3 antagonist5-HT3 antagonist
Zhu LP, Ye DY, Tang Y (January 2007). "Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists". Journal of ...
https://en.wikipedia.org/wiki/5-HT3_antagonist
LY3372689LY3372689
The molecule contains three rings: thiazole, piperidine and oxadiazole. Other functional groups included are an ether, ... Thiazoles, Piperidines, Acetamides, Ethers, Organofluorides, All stub articles, Pharmacology stubs). ...
https://en.wikipedia.org/wiki/LY3372689
Non steroidal aromatase inhibitorsNon steroidal aromatase inhibitors
... thiazole derivatives". Bioorganic & Medicinal Chemistry. 26 (8): 1986-1995. doi:10.1016/j.bmc.2018.02.048. ISSN 0968-0896. PMID ...
https://en.wikipedia.org/wiki/Non_steroidal_aromatase_inhibitors
Heterocyclic compoundHeterocyclic compound
Thiazoles and isothiazoles contain a sulfur and a nitrogen atom in the ring. Dithiolanes have two sulfur atoms. A large group ...
https://en.wikipedia.org/wiki/Heterocyclic_compound
ThiazolineThiazoline
Thiazole - an analogue with 2 double bonds Thiazolidine - an analogue with no double bonds Oxazoline - an analogue with O in ... The amino acid cysteine is produced industrially from substituted thiazole. 2-Aminothiazoline-4-carboxylic acid is an ...
https://en.wikipedia.org/wiki/Thiazoline
Host-guest chemistryHost-guest chemistry
In this study they used thiazole orange as the indicator. The helicase unwinds the dsDNA to make ssDNA. The fluorescence ... Biancardi, Alessandro; Tarita, Biver; Alberto, Marini; Benedetta, Mennucci; Fernando, Secco (2011). "Thiazole orange (TO) as a ... intensity of thiazole orange has a greater affinity for dsDNA than ssDNA and its fluorescence intensity increases when it is ...
https://en.wikipedia.org/wiki/Host–guest_chemistry
ThiamineThiamine
The thiazole ring is formed in a reaction catalysed by thiazole synthase (EC 2.8.1.10). The ultimate precursors are 1-deoxy-D- ... The thiazole is substituted with methyl and hydroxyethyl side chains. Thiamine is stable at acidic pH, but it is unstable in ... The thiazole and pyrimidine moieties are biosynthesized separately and are then combined to form ThMP by the action of thiamine ... Thiamine and its metabolites (2-methyl-4-amino-5-pyrimidine carboxylic acid, 4-methyl-thiazole-5-acetic acid, and others) are ...
https://en.wikipedia.org/wiki/Thiamine
PlantazolicinPlantazolicin
This process converts cysteine and serine/threonine residues into thiazole and (methyl)oxazole heterocycles (as seen to the ... Melby, Joel O.; Nard, Nathan J.; Mitchell, Douglas A. (2011). "Thiazole/Oxazole-modified microcins: Complex natural products ... it can be classified further as a thiazole/oxazole-modified microcin (TOMM) or a linear azole-containing peptide (LAP). The ... Structure Elucidation of Ribosomally Synthesized Thiazole/Oxazole Peptides from Bacillus amyloliquefaciensFZB42". Organic ...
https://en.wikipedia.org/wiki/Plantazolicin
ThiazolidineThiazolidine
Thiazole Thiazoline International Union of Pure and Applied Chemistry (2014). Nomenclature of Organic Chemistry: IUPAC ...
https://en.wikipedia.org/wiki/Thiazolidine
HydrofuramideHydrofuramide
M. Bravar; Jelencic, J.; Dabetic, M. (1988). "Kinetics of additive-containing sulfur-thiazole vulcanization of styrene- ...
https://en.wikipedia.org/wiki/Hydrofuramide
AminothiazoleAminothiazole
2-Aminothiazole is a heterocyclic amine featuring a thiazole core. It can also be considered a cyclic isothiourea. It possesses ...
https://en.wikipedia.org/wiki/Aminothiazole
Thiamine pyrophosphateThiamine pyrophosphate
Thus, the thiazole ring is the "reagent portion" of the molecule. The C2 of this ring is capable of acting as an acid by ... The part of TPP molecule that is most commonly involved in reactions is the thiazole ring, which contains nitrogen and sulfur. ... TPP consists of a pyrimidine ring which is connected to a thiazole ring, which is in turn connected to a pyrophosphate ( ...
https://en.wikipedia.org/wiki/Thiamine_pyrophosphate
Hauser baseHauser base
Shilai, M.; Kondo, Y.; Sakamoto, T. (2001). "Selective metallation of thiophene and thiazole rings with magnesium amide base". ...
https://en.wikipedia.org/wiki/Hauser_base
OxathiazolonesOxathiazolones
Thiazole and isothiazole, analogues without the carbonyl group or oxygen atom. Oxazole and isoxazole, analogues without the ...
https://en.wikipedia.org/wiki/Oxathiazolones
CefdinirCefdinir
The bromoketone array in that intermediate constitutes a classical starting function for construction of thiazoles. Reaction of ... Thiazoles, AbbVie brands, Astellas Pharma, Vinyl compounds). ...
https://en.wikipedia.org/wiki/Cefdinir
Anne McNeilAnne McNeil
"Impact of Preferential π-Binding in Catalyst-Transfer Polycondensation of Thiazole Derivatives". ACS Macro Lett. 5 (12): 1411- ...
https://en.wikipedia.org/wiki/Anne_McNeil
AlkaloidAlkaloid
... thiazole and peptide alkaloids, and other miscellaneous alkaloids". Nat. Prod. Rep. 17 (1): 57-84. doi:10.1039/a809403i. PMID ...
https://en.wikipedia.org/wiki/Alkaloid
OxazolidineOxazolidine
Thiazole, an analog with the oxygen atom replaced by a sulfur atom. Benzoxazole, where the oxazole is fused to another aromatic ...
https://en.wikipedia.org/wiki/Oxazolidine
NitroimidazoleNitroimidazole
Other heterocycles such as nitrothiazoles (thiazole) are also used for this purpose. Nitroheterocycles may be reductively ...
https://en.wikipedia.org/wiki/Nitroimidazole
Browsing by Subject ThiazolesBrowsing by Subject "Thiazoles"
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://extranet.who.int/iris/restricted/browse?authority=Thiazoles&type=mesh
Thiazole, 4,5-dimethylThiazole, 4,5-dimethyl
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/cbook.cgi?ID=C3581917&Units=SI&Mask=FFFF
Thiazole derivatives - Patent US-6344562-B1 - PubChemThiazole derivatives - Patent US-6344562-B1 - PubChem
US-6344562-B1 chemical patent summary.
https://pubchem.ncbi.nlm.nih.gov/patent/US-6344562-B1
ethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylateethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylate
... Molecular Formula: C13H10F3NO2S ...
https://scitoys.com/scichem/jqp033/2737237.html
Allyl aniline : the synthesis of certain thiazolesAllyl aniline : the synthesis of certain thiazoles
The University of Kansas prohibits discrimination on the basis of race, color, ethnicity, religion, sex, national origin, age, ancestry, disability, status as a veteran, sexual orientation, marital status, parental status, gender identity, gender expression and genetic information in the Universitys programs and activities. The following person has been designated to handle inquiries regarding the non-discrimination policies: Director of the Office of Institutional Opportunity and Access, [email protected], 1246 W. Campus Road, Room 153A, Lawrence, KS, 66045, (785)864-6414, 711 TTY. ...
https://kuscholarworks.ku.edu/handle/1808/18553
Thiazole Red (TO-PRO®-3), 1 mM in DMSO - BiotiumThiazole Red (TO-PRO®-3), 1 mM in DMSO - Biotium
Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant nucleic acid stain with ex/em of 642/657 nm (with DNA). ... Thiazole Red (TO-PRO®-3), 1 mM in DMSO Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant, high-affinity far-red ... Thiazole Red Homodimer (TOTO®-3), 1 mM in DMSO Thiazole red homodimer (TRhD), also known as TOTO®-3, is a cell-impermeant, high ... Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is ...
https://biotium.com/product/thiazole-red-1mm-in-dmso/
Synthesis, anticandidal activity, and cytotoxicity of some thiazole de by LEYLA YURTTAŞ, YUSUF ÖZKAY et al."Synthesis, anticandidal activity, and cytotoxicity of some thiazole de" by LEYLA YURTTAŞ, YUSUF ÖZKAY et al.
Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal ... Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal ... Synthesis, anticandidal activity, and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains ... and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains," Turkish Journal of Chemistry: Vol. 38: No. 5, ...
https://journals.tubitak.gov.tr/chem/vol38/iss5/13/
Ethyl-2-(2-amino-4-thiazole-4-yl)acetic acid, China Ethyl-2-(2-amino-4-thiazole-4-yl)acetic acid Manufacturers, China Ethyl-2-...
2-amino-4-thiazole-4-yl)acetic acid product and the products related with China Ethyl-2-(2-amino-4-thiazole-4-yl)acetic acid - ... 2-amino-4-thiazole-4-yl)acetic acid Manufacturers, provide Ethyl-2-( ... 2-amino-4-thiazole-4-yl)acetic acid Suppliers and China Ethyl-2-( ... Send your inquiry to Ethyl-2-(2-amino-4-thiazole-4-yl)acetic ... China Ethyl-2-(2-amino-4-thiazole-4-yl)acetic acid Suppliers, China Ethyl-2-(2-amino-4-thiazole-4-yl)acetic acid Manufacturers. ...
http://www.chemnet.com/ChinaSuppliers/19796/Ethyl-2-
We Prepared a Set of Functionalized 1,3-Thiazoles to Power Up Your Research | Building Blocks | Blog | Life ChemicalsWe Prepared a Set of Functionalized 1,3-Thiazoles to Power Up Your Research | Building Blocks | Blog | Life Chemicals
3-thiazole building blocks for anti-tumor, antifungal, and enzyme-inhibiting research. ... 1,3-Thiazole-derived fluorescent dyes, such as Thiazole Orange 3, have found important applications in cytometry as "light-up" ... 1,3-Thiazole is a privileged scaffold in drug discovery. Many thiazole-based compounds have anti-tumor, antifungal, and enzyme- ... Some selected structures featuring a 1,3-thiazole ring are listed below. The full database of the functionalized 1,3-thiazoles ...
https://lifechemicals.com/blog/building-blocks/343-we-prepared-a-set-of-functionalized-1,3-thiazoles-to-power-up-your-research
6-phenyl-5-(4-pyridinyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole - C16H13N3S, density, melting point, boiling point, structural...
... thiazole - C16H13N3S, synthesis, structure, density, melting point, boiling point ... thiazole , density of 6-phenyl-5-(4-pyridinyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole , refractive index of 6-phenyl-5-(4- ... Tags: melting point of 6-phenyl-5-(4-pyridinyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole , boiling point of 6-phenyl-5-(4- ... 6-phenyl-5-pyridin-4-yl-3,4-dihydro-2H-imidazo[2,1-b]thiazole ...
https://www.chemsynthesis.com/base/chemical-structure-11690.html
2-(Dimethylaminomethyl)-4-(2-Aminoethylthiomethyl)Thiazole Properties, Molecular Formula, Applications - WorldOfChemicals2-(Dimethylaminomethyl)-4-(2-Aminoethylthiomethyl)Thiazole Properties, Molecular Formula, Applications - WorldOfChemicals
Get 2-(Dimethylaminomethyl)-4-(2-Aminoethylthiomethyl)Thiazole molecular formula, CAS number, boiling point, melting point, ...
https://www.worldofchemicals.com/chemicals/chemical-properties/2-dimethylaminomethyl-4-2-aminoethylthiomethylthiazole.html
2-BROMO-4-METHOXYBENZO[D]THIAZOLE2-BROMO-4-METHOXYBENZO[D]THIAZOLE
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser. ...
https://www.dougdiscovery.com/2-bromo-4-methoxybenzo-d-thiazole.html
Copper(II) bis-thiazole complex immobilized on silica nanoparticlesCopper(II) bis-thiazole complex immobilized on silica nanoparticles
... : Preparation, characterization and its application as a ...
https://www.researcher-app.com/paper/106697
where to buy Thiazoleswhere to buy Thiazoles
We also provide custom synthesis and GMP manufacturing services.where to buy Thiazoles ... where to buy Thiazoles, Chemenu is research-based manufacturer of pharmaceutical intermediates and fine chemicals offering ... Thiazoles. Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of ... Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic ...
https://www.chemenu.com/category/20.html
2-Furfurylthio thiazole - organotin2-Furfurylthio thiazole - organotin
与2-Furfurylthio thiazole 相关的文章列表 ...
https://www.organotin.org/archives/tag/2-furfurylthio-thiazole
Chemistry of the thiazoles. Part I. Synthesis of 5-aminothiazole derivatives - Publications of the IAS FellowsChemistry of the thiazoles. Part I. Synthesis of 5-aminothiazole derivatives - Publications of the IAS Fellows
Ganapathi, K. ; Venkataraman, Alamela (1945) Chemistry of the thiazoles. Part I. Synthesis of 5-aminothiazole derivatives ...
http://repository.ias.ac.in/11387/
ethyl 5-amino-2-(methylamino)-1,3-thiazole-4-carboxylate AldrichCPR | Sigma-Aldrichethyl 5-amino-2-(methylamino)-1,3-thiazole-4-carboxylate AldrichCPR | Sigma-Aldrich
3-thiazole-4-carboxylate AldrichCPR; CAS Number: 52868-72-1; Linear Formula: C7H11N3O2S; find -PH008652 MSDS, related peer- ...
https://www.sigmaaldrich.cn/CN/zh/product/aldrich/ph008652
Browsing by Subject
Thiazoles [‎4]‎. Thimerosal [‎1]‎. Thiocarbamates [‎1]‎. Thiophosphoric Acid Esters [‎4]‎. Thioridazine [‎1]‎. ...
https://apps.who.int:80/iris/browse?rpp=20&offset=5778&etal=-1&sort_by=-1&type=mesh&starts_with_previous=T&order=ASC
Thiazole RX01 Qingdao Ruxiang Technology Co., Ltd.Thiazole RX01 Qingdao Ruxiang Technology Co., Ltd.
The bactericidal mechanism of the thiazole fungicide is that it can penetrate the microbial cell membrane into the nucleus and ... Thiazole RX01-Qingdao Ruxiang Technology Co., Ltd.-Product Overview: ... Product Overview: The bactericidal mechanism of the thiazole fungicide is that it can penetrate the microbial cell membrane ...
http://en.ruxiangchemical.com/product/61.html
IMSEAR at SEARO: Heterocyclic systems containing bridgehead nitrogen atom. 13. Antifungal and antibacterial activities of...
Antifungal and antibacterial activities of thiazole and thiazolidinone derivatives.. Authors: Mohan, J. Chadha, V K. Chaudhary ... Antifungal and antibacterial activities of thiazole and thiazolidinone derivatives. Indian Journal of Experimental Biology. ...
https://imsear.searo.who.int/handle/123456789/57099?locale=ar
PEACH THIAZOLE 1% ETOH NATURAL 1360 - Advanced BiotechPEACH THIAZOLE 1% ETOH NATURAL 1360 - Advanced Biotech
2022 Advanced Biotech , 10 Taft Road , Totowa, NJ 07512 , Phone: (973)339-6242 , Fax: (973)256-4101. ...
https://www.adv-bio.com/peach-thiazole-1-etoh-natural-1360/
2-Ethyl-4-Methyl Thiazole Manufacturer, Supplier, Exporter
Buy 2-Ethyl-4-Methyl Thiazole online at reasonable price. A. B. ENTERPRISES is based out in Mumbai, Maharashtra, India. Some of ...
https://m.dyechemindia.com/2-ethyl-4-methyl-thiazole-5370797.html
4-Methyl-5 Vinyl Thiazole Manufacturer,Exporter,Supplier4-Methyl-5 Vinyl Thiazole Manufacturer,Exporter,Supplier
... supplier and exporter of 4-Methyl-5 Vinyl Thiazole. We offer best quality of 4-Methyl-5 Vinyl Thiazole at a best price. These ... 4-Methyl-5 Vinyl Thiazole is water insoluble in nature and shows solubility in alcohol. It can be availed at market leading ... 4-Methyl-5 Vinyl Thiazole is a chemical compound with nutty odor and clear colorless appearance in liquid form. It has ...
https://www.aromaaromatics.net/4-methyl-5-vinyl-thiazole-4159078.html
Search OdorsSearch Odors
4,5 DIMETHYL THIAZOLE. Meaty, Nutty. 5 BETA-HYDROXY-ETHYL-4-METHYL THIAZOLE (Sulfurol). Beef, nutty. ...
https://www.atsdr.cdc.gov/odors/search_results.html
TPL and Drug Sensitivity of Resistant Leukemia Cell LinesTPL and Drug Sensitivity of Resistant Leukemia Cell Lines
HL60/A cells were exposed to DOX with or without TPL (14 nM) for 48 h in vitro with IC50 detected by methyl thiazole ... Cytotoxicity of TPL to HL60, HL60/A, K562 and K562/G was determined using an methyl thiazole tetrazolium bromide (MTT) assay. ... After 24 h of drug exposure the cytotoxicity and IC50 values were determined by methyl thiazole tetrazolium bromide assay.. ... Methyl Thiazole Tetrazolium Bromide Proliferation Cytotoxicity Assay. Drug cytotoxicity was determined using the colorimetric ...
https://www.medscape.com/viewarticle/809638_2
Formation constant of lanthanide metal ion with substituted thiazole Schiff base in mixed solvent media and thermodynamic...Formation constant of lanthanide metal ion with substituted thiazole Schiff base in mixed solvent media and thermodynamic...
Formation constant of lanthanide metal ion with substituted thiazole Schiff base in mixed solvent media and thermodynamic ... Formation constant of lanthanide metal ion with substituted thiazole Schiff base in mixed solvent media and thermodynamic ... Formation constant of lanthanide metal ion with substituted thiazole Schiff base in mixed solvent media and thermodynamic ...
https://www.chemijournal.com/archives/?year=2020&vol=8&issue=2&ArticleId=8745&si=false
Isopropyl-2 4-methyl Thiazole 1% in Ethyl Alcohol | VigonIsopropyl-2 4-methyl Thiazole 1% in Ethyl Alcohol | Vigon
Hazard Statement: Highly flammable liquid and vapor. Causes mild skin irritation. Causes serious eye irritation. May cause respiratory irritation. May cause drowsiness or dizziness. Precautionary Statement: -PREVENTION- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Keep container tightly closed. Ground and bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting equipment. Use non-sparking tools. Take action to prevent static discharges. Avoid breathing mist or vapor. Wash thoroughly after handling. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection ...
https://www.vigon.com/product/isopropyl-2-4-methyl-thiazole-1-in-ethyl-alcohol/
2,4-dibromo-1,3-thiazole-5-carbaldehyde - Chemlyte solutions2,4-dibromo-1,3-thiazole-5-carbaldehyde - Chemlyte solutions
2,4-dibromo-1,3-thiazole-5-carbaldehyde. For more information please contact us at [email protected] or Inquire with ...
https://chemlytesolutions.com/chemlyte_products/24-dibromo-13-thiazole-5-carbaldehyde/
Synthesis and Characterization of Ethycarbazole and Thiazole Containing Polymers | AVESİSSynthesis and Characterization of Ethycarbazole and Thiazole Containing Polymers | AVESİS
In this study bis (ethylcarbazole) diethylthiazole (ECzEBTECz) comonomer was synthesized by Stille coupling reaction and then electrochemically polymerized. The redox behaviour of resulting polymer, P [ECzEBTECz] was investigated by cyclic voltammetry at different scan rates. Polymeric film was further characterized by ATR-FTIR, UV-Visible and fluorescence spectrophotometric measurements. The capacitive behaviour of polymer was investigated by electrochemical impedance spectroscopic (EIS) measurements. Electrical equivalent circuit was applied to the experimental data to correlate the results, obtain the parameter of each element and explain the interface between the glassy carbon/P[ECzEBTECz]/Bu4NPF6 system. Voltammetry results show that the redox behaviour of the polymeric film is quite reversible and stable even at high scan rates. Fluorescence measurements suggest that the emission of the bithiazole moiety allows access to full visible spectrum so the color of polymer expected to suit to the ...
https://avesis.itu.edu.tr/yayin/c202fe94-8f32-460a-82a8-b0ba1bdb587c/synthesis-and-characterization-of-ethycarbazole-and-thiazole-containing-polymers
Synthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene...Synthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene...
Theoretical harmonic frequencies of ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate (1) were optimized. ... a thiazole ester, was synthesized by refluxing 1-(2-nitrobenzylidene)thiosemicarbazide and ethyl bromopyruvate. The compound is ... thiazole-4-carboxylate (1) was also evaluated for its anti-oxidant and anti-microbial activities. ... a vital role for this relatively small HOMO-LUMO gape and overall electronic properties when compared with similar thiazole ...
https://bmcchem.biomedcentral.com/articles/10.1186/s13065-022-00805-1/tables/5
DerivativesSynthesisEthylPhenylMETHYL THIAZOLEPolymersInsolubleAntibacterialThiamineSolubilityCharacterizationSolventNuttyHeterocyclesMechanismThiopheneChemistryStructuresStructuralOrganicProductsRingsApplicationsDrugFoundCell
Derivatives4
  • Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal activity and cytotoxicity. (tubitak.gov.tr)
  • 13. Antifungal and antibacterial activities of thiazole and thiazolidinone derivatives. (who.int)
  • A number of derivatives of thiazole have been synthesized from Hantzsh Method. (fip.org)
  • Combination of structural elements from a potent Y5 antagonist (2) with thiazole fragments that exhibit weak Y5 affinities followed by lead optimisation led to the discovery of (5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-yl)-piperidin-4-ylmethyl-amino and (4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen-2-yl)-piperidin-4-ylmethyl-amino derivatives. (novartis.com)
Synthesis3
  • Synthesis, anticandidal activity, and cytotoxicity of some thiazole de" by LEYLA YURTTAŞ, YUSUF ÖZKAY et al. (tubitak.gov.tr)
  • 5 1,3-Thiazoles are also indispensable in organic synthesis as place-holding groups for the formyl functionality 6 and chiral auxiliaries 7 in asymmetric reactions. (lifechemicals.com)
  • A general synthesis of thiazoles. (ias.ac.in)
Ethyl1
  • For more information, please view Spec of ethyl 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate 117724-62-6.pdf . (capotchem.com)
Phenyl1
  • In this study we investigated whether the intrathecal administration (i.t.) of the novel pyrazolyl-thiazole derivative 2-[5-trichloromethyl-5-hidroxy-3-phenyl-4,5-dihydro-1 H -pyrazol-1-yl]-4-(4-bromophenyl)-5-methylthiazole (B50)Â caused antinociception in adult male mice, using the hot plate and acetic acid writhing assays. (edu.br)
METHYL THIAZOLE1
  • Drug cytotoxicity was determined using the colorimetric methyl thiazole tetrazolium bromide (MTT) proliferation assay. (medscape.com)
Polymers1
  • Technology benefits from thiazole-containing semiconducting conjugated polymers 8 and catalysts, such as compound 4 9 in Fig. 1. (lifechemicals.com)
Insoluble4
  • 4-Methyl-5 Vinyl Thiazole is water insoluble in nature and shows solubility in alcohol. (aromaaromatics.net)
  • However, zinc thiazole is highly insoluble in water and in most organic solvents. (biomedcentral.com)
  • 2012 ). This zinc complex is an insoluble molecule and is commercially available as zinc thiazole suspension concentrate (SC) since 2007. (biomedcentral.com)
  • However, the insoluble property of zinc thiazole greatly limits its activity. (biomedcentral.com)
Antibacterial2
  • Taken together, this study provides for the first time a method for dissolving zinc thiazole, and may help to better understand the antibacterial mechanism of zinc thiazole. (biomedcentral.com)
  • The antibacterial mechanism of zinc thiazole (in DMSO solvent) against Xoo strain PXO99 was investigated, and the protective and curative activities of zinc thiazole against rice bacterial blight were determined. (biomedcentral.com)
Thiamine2
  • From left to right, Tube 1 contained growth medium plus only casein, Tube 2 contained growth medium plus casein and thiamine, and Tube 3 contained growth medium plus casein and thiazole. (cdc.gov)
  • Based on the results of this particular test, this strain of T. concentricum was dependent on the thiazole portion of the thiamine molecule, based on the enhanced growth in tubes 2, which contained thiamine, and 3, which contained thiazole. (cdc.gov)
Solubility1
  • In this work, we found for the first time that zinc thiazole can be dissolved in dimethyl sulfoxide (DMSO), and the solubility of zinc thiazole in DMSO is more than 20 mg/mL. (biomedcentral.com)
Characterization1
  • Mallakpour S, Zadehnazari A, Functionalized Multi-Walled Carbon Nanotubes with Vitamin C Structures: Characterization and Fabricat ion of Thiazole Containing Poly(Amide-Imide)-based Composites, Polymer-Plastics Technology and Engineering, 2015. (ac.ir)
Solvent1
  • In this study, dimethylsulfoxide (DMSO) was found to be a suitable solvent to dissolve zinc thiazole. (biomedcentral.com)
Nutty1
  • 4-Methyl-5 Vinyl Thiazole is a chemical compound with nutty odor and clear colorless appearance in liquid form. (aromaaromatics.net)
Heterocycles1
  • The thiazole ring system comprises a five membered aromatic heterocycles, substituted with a nitrogen and a sulphur atom, commonly in the 1,3 thiazole or 1,2 iso-thiazole positions. (fip.org)
Mechanism1
  • Product Overview: The bactericidal mechanism of the thiazole fungicide is that it can penetrate the microbial cell membrane into the nucleus and bind to the base pair in the nucleus, thereby destroying the replication of the DNA and killing the microorganism. (ruxiangchemical.com)
Thiophene1
  • To increase ligand efficiency, the thiophene ring was replaced bioisosterically by a thiazole ring, and the pyran ring was opened. (elsevier.com)
Chemistry2
  • Thiazoles are very important functional groups in medicinal chemistry. (chemenu.com)
  • Chemistry of the thiazoles. (ias.ac.in)
Structures1
  • Some selected structures featuring a 1,3-thiazole ring are listed below. (lifechemicals.com)
Structural1
  • The structural unit of substituted 1,3-thiazole is ubiquitous in natural products and synthetic materials. (lifechemicals.com)
Organic1
  • The thiazole ring has been reported to be soluble in organic solvents (Kashyap et al. (biomedcentral.com)
Products1
  • Thiazole-containing natural products isolated from cyanobacteria of different marine organisms include small linear peptides ( e.g. , nordysidenin 1 in Fig. 1), linear oligopeptides (so-called Apramidas), cyclic peptides ( e.g. , tenuecyclamide A 2 in Fig. 1), and alkaloids. (lifechemicals.com)
Rings1
  • Thiamin pyrophosphate (TPP) and its component parts: the pyrimidine and thiazole rings, and the pyrophosphate (or "diphosphate") moiety. (medlink.com)
Applications1
  • 1,3-Thiazole-derived fluorescent dyes, such as Thiazole Orange 3 , have found important applications in cytometry as "light-up" probes for DNA. (lifechemicals.com)
Drug1
Found2
  • 2 Moreover, a few macrocycles and cyclic lactones bearing the thiazole ring were found in some soil bacteria extracts. (lifechemicals.com)
  • Zinc thiazole is found safe to non-target organisms and easy to be degraded in soil (Wei et al. (biomedcentral.com)
Cell3
  • Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant, high-affinity far-red nucleic acid stain. (biotium.com)
  • Interestingly, zinc thiazole at 25 μg/mL enhanced the cell division and altered the cell wall integrity of Xoo . (biomedcentral.com)
  • Thiostrepton (TS) is a thiazole antibiotic that inhibits expression of FOXM1, an oncogenic transcription factor required for cell cycle progression and resistance to oncogene-induced oxidative stress. (cdc.gov)
Thiazole, 4,5-dimethyl
Thiazole, 4,5-dimethyl (webbook.nist.gov)
In-vitro cytotoxic screening of Glycyrrhiza glabra L. (Fabaceae): A natural anticancer drug
In-vitro cytotoxic screening of Glycyrrhiza glabra L. (Fabaceae): A natural anticancer drug (researchgate.net)
Ethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylate
Ethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylate (scitoys.com)
Handan Kaitai Pharmaceutical Technology Co., Ltd--4-Methyl-1,3-thiazole-5-carboxylic acid,1,1'-Carbo
Handan Kaitai Pharmaceutical Technology Co., Ltd--4-Methyl-1,3-thiazole-5-carboxylic acid,1,1'-Carbo (changdapharm.com)
Abstracts - FIP - International Pharmaceutical Federation
Abstracts - FIP - International Pharmaceutical Federation (fip.org)
Journal of Chemical Sciences | Indian Academy of Sciences
Journal of Chemical Sciences | Indian Academy of Sciences (ias.ac.in)
Zeitschrift für Naturforschung C Volume 76 Issue 11-12
Zeitschrift für Naturforschung C Volume 76 Issue 11-12 (degruyter.com)
ISOPENTANOL - Pierron
ISOPENTANOL - Pierron (pierron.fr)
Bacillamide C: the convergent approach - Organic & Biomolecular Chemistry (RSC Publishing)
Bacillamide C: the convergent approach - Organic & Biomolecular Chemistry (RSC Publishing) (pubs.rsc.org)
Ethylene Carbonate Manufacturers, Ethylene Carbonate Suppliers, Exporters
Ethylene Carbonate Manufacturers, Ethylene Carbonate Suppliers, Exporters (tradeindia.com)
4 Methoxy Phenyl Acetone Manufacturers, Suppliers, Dealers & Prices
4 Methoxy Phenyl Acetone Manufacturers, Suppliers, Dealers & Prices (tradeindia.com)
Research - Professor Iain McCulloch
Research - Professor Iain McCulloch (imperial.ac.uk)
Polymers | Free Full-Text | Designing High-Refractive Index Polymers Using Materials Informatics
Polymers | Free Full-Text | Designing High-Refractive Index Polymers Using Materials Informatics (mdpi.com)
AR-AO-14418: Uses, Interactions, Mechanism of Action | DrugBank Online
AR-AO-14418: Uses, Interactions, Mechanism of Action | DrugBank Online (go.drugbank.com)
Nomenclature Des Carbocycles Et Des Hetero Cycles | PDF | Groupe fonctionnel | Hétérocycle
Nomenclature Des Carbocycles Et Des Hetero Cycles | PDF | Groupe fonctionnel | Hétérocycle (fr.scribd.com)
Search Results
Search Results (webbook.nist.gov)
MeSH Browser
MeSH Browser (meshb.nlm.nih.gov)
Full publication list | Max Planck Institute for Polymer Research
Full publication list | Max Planck Institute for Polymer Research (mpip-mainz.mpg.de)
Subrahmanya K | Professor (Associate) | MSc, PhD
Subrahmanya K | Professor (Associate) | MSc, PhD (researchgate.net)
Kimtech™ G3 White Nitrile Gloves (62815), ISO Class 3 or Higher Cleanrooms, High Tack Grip, Ambidextrous, 12, XL, Double...
Kimtech™ G3 White Nitrile Gloves (62815), ISO Class 3 or Higher Cleanrooms, High Tack Grip, Ambidextrous, 12", XL, Double... (kcprofessional.com)
Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling | bioRxiv
Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling | bioRxiv (biorxiv.org)
Frontiers | Membrane Thickness as a Key Factor Contributing to the Activation of Osmosensors and Essential Ras Signaling...
Frontiers | Membrane Thickness as a Key Factor Contributing to the Activation of Osmosensors and Essential Ras Signaling... (frontiersin.org)
Publications
Publications (people.uncw.edu)
BindingDB PrimarySearch_ki
BindingDB PrimarySearch_ki (bindingdb.org)
Synthesis, anticandidal activity, and cytotoxicity of some thiazole de by LEYLA YURTTAŞ, YUSUF ÖZKAY et al.
"Synthesis, anticandidal activity, and cytotoxicity of some thiazole de" by LEYLA YURTTAŞ, YUSUF ÖZKAY et al. (journals.tubitak.gov.tr)
HeteroCycles
HeteroCycles (heterocycles.jp)