Tetralogy of Fallot
A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.
Pulmonary Valve Insufficiency
Pulmonary Valve Stenosis
Pulmonary Atresia
A congenital heart defect characterized by the narrowing or complete absence of the opening between the RIGHT VENTRICLE and the PULMONARY ARTERY. Lacking a normal PULMONARY VALVE, unoxygenated blood in the right ventricle can not be effectively pumped into the lung for oxygenation. Clinical features include rapid breathing, CYANOSIS, right ventricle atrophy, and abnormal heart sounds (HEART MURMURS).
Heart Defects, Congenital
Ventricular Function, Right
Heart Septal Defects, Ventricular
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Cyanosis
Trilogy of Fallot
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Ventricular Outflow Obstruction
Pulmonary Artery
Postoperative Complications
Pulmonary Subvalvular Stenosis
Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. It is characterized by restricted blood outflow from the RIGHT VENTRICLE into the PULMONARY ARTERY, exertional fatigue, DYSPNEA, and chest discomfort.
Echocardiography
Heart Ventricles
Tricuspid Valve
Heart Septal Defects
Hypertrophy, Right Ventricular
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Tachycardia, Ectopic Junctional
A rare form of supraventricular tachycardia caused by automatic, not reentrant, conduction initiated from sites at the atrioventricular junction, but not the ATRIOVENTRICULAR NODE. It usually occurs during myocardial infarction, after heart surgery, or in digitalis intoxication with a HEART RATE ranging from 140 to 250 beats per minute.
Chromosomes, Human, Pair 22
Dilatation, Pathologic
Truncus Arteriosus, Persistent
A congenital anomaly caused by the failed development of TRUNCUS ARTERIOSUS into separate AORTA and PULMONARY ARTERY. It is characterized by a single arterial trunk that forms the outlet for both HEART VENTRICLES and gives rise to the systemic, pulmonary, and coronary arteries. It is always accompanied by a ventricular septal defect.
Tachycardia, Ventricular
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
Reoperation
Heart Valve Prosthesis Implantation
Bethanidine
Arrhythmias, Cardiac
Coronary Vessel Anomalies
Echocardiography, Doppler
Cardiac Catheterization
Follow-Up Studies
Treatment Outcome
Malta
An independent state consisting of three islands in the Mediterranean Sea, south of Sicily. Its capital is Valetta. The major island is Malta, the two smaller islands are Comino and Gozo. It was a Phoenician and Carthaginian colony, captured by the Romans in 218 B.C. It was overrun by Saracens in 870, taken by the Normans in 1090, and subsequently held by the French and later the British who allotted them a dominion government in 1921. It became a crown colony in 1933, achieving independence in 1964. The name possibly comes from a pre-Indoeuropean root mel, high, referring to its rocks, but a more picturesque origin derives the name from the Greek melitta or melissa, honey, with reference to its early fame for its honey production. (From Webster's New Geographical Dictionary, 1988, p719 & Room, Brewer's Dictionary of Names, 1992, p330)
Blalock-Taussig Procedure
Magnetic Resonance Imaging, Cine
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
Double Outlet Right Ventricle
Incomplete transposition of the great vessels in which both the AORTA and the PULMONARY ARTERY arise from the RIGHT VENTRICLE. The only outlet of the LEFT VENTRICLE is a large ventricular septal defect (VENTRICULAR SEPTAL DEFECTS or VSD). The various subtypes are classified by the location of the septal defect, such as subaortic, subpulmonary, or noncommitted.
Stroke Volume
Cardiopulmonary Bypass
Transposition of Great Vessels
A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
Heart Septal Defects, Atrial
Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.
Balloon Valvuloplasty
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Outcome of pregnancy in women with congenital shunt lesions. (1/500)
OBJECTIVE: To evaluate the outcome of pregnancy in women with congenital shunt lesions. SETTING: Retrospective study in a tertiary care centre. METHODS: Pregnancy history was obtained by a standardised questionnaire and medical records were reviewed. PATIENTS: 175 women were identified, at a mean (SD) age of 42 (14) years. Pregnancies occurred in 126 women: 50 with an atrial septal defect, 22 with a ventricular septal defect, 22 with an atrioventricular septal defect, 19 with tetralogy of Fallot, and 13 with other complex shunt lesions. RESULTS: 309 pregnancies were reported by 126 woman (2.5 (1.6) pregnancies per woman). The shortening fraction of the systemic ventricle was 40 (8)%, and 98% were in New York Heart Association class I-II at last follow up. Spontaneous abortions occurred in 17% of pregnancies (abortion rate, 0.4 (0.9) per woman). Gestational age of the 241 newborn infants was 8.8 (0.8) months. There were no maternal deaths related to pregnancy. Pre-eclampsia and embolic events were observed in 1.3% and 0.6%, respectively of all pregnancies. Women with complex shunt lesions more often underwent caesarean section (70% v 15-30%, p = 0.005) and gave birth to smaller babies for equivalent gestation (2577 (671) g v 3016 (572) to 3207 (610) g, p < 0.05). The recurrence risk of congenital heart disease was 2.5%. CONCLUSIONS: The outcome of pregnancy is favourable in women with congenital shunt lesions if their functional class and their systolic ventricular function are good. Such patients can be reassured. (+info)Echocardiographic and morphological correlations in tetralogy of Fallot. (2/500)
AIMS: Our aim was to clarify the location and structure of the outlet septum relative to the free-standing subpulmonary infundibulum in the setting of tetralogy of Fallot and to examine its relationship to the other components of the subpulmonary outflow tract, determining their potential influence on clinical outcome. METHODS AND RESULTS: We studied prospectively 41 patients with tetralogy of Fallot (mean age 14 +/- 10.9 months) prior to surgical repair, and compared them with 15 patients undergoing closure of a ventricular septal defect associated with malalignment of the outlet septum but no subpulmonary infundibular stenosis (Eisenmenger ventricular septal defect), and 20 healthy controls. We also examined available autopsied hearts from cases with uncorrected tetralogy of Fallot (8) and Eisenmenger ventricular septal defect (13). Data were indexed for body surface area, and diameter of the tricuspid valve, respectively. The overall length of the subpulmonary infundibulum, including the extent of the muscular outlet septum, was significantly greater for patients with tetralogy of Fallot compared to normals (2.34 +/- 0.6 vs 1.46 +/- 0.34 cm/BSA0.5, P<0.001), whereas the difference between those with tetralogy of Fallot and an Eisenmenger ventricular septal defect was confined to the degree of narrowing of the subpulmonary outlet (0.43 +/- 0.22 vs 2.17 +/- 0.64 cm/BSA0.5, P<0.001). Within the tetralogy of Fallot group, there were linear relationships between deviation of the outlet septum (r= -0.61, P<0.005) and the diameter of the pulmonary valvar orifice (r=0.75, P<0.001), suggesting that growth of the pulmonary arteries may be related to this feature. When patients requiring a transannular patch as part of their surgical repair were compared with those not needing this procedure, differences were found in the diameter of the pulmonary valvar orifice and the pulmonary trunk, but not in the dimensions of the outlet septum. CONCLUSION: The position of the outlet septum in relationship to the remainder of the muscular subpulmonary infundibulum represents a hallmark of tetralogy of Fallot, permitting its differentiation from Eisenmenger ventricular septal defects and normal hearts. (+info)Decreased left ventricular filling pressure 8 months after corrective surgery in a 55-year-old man with tetralogy of Fallot: adaptation for increased preload. (3/500)
A 55-year-old man with tetralogy of Fallot underwent corrective surgery. Left ventricular filling pressure increased markedly with increased left ventricular volume one month after surgery, then decreased over the next 7 months, presumably due to increased left ventricular compliance. (+info)Disopyramide improves hypoxia in patients with tetralogy of Fallot through a negative inotropic action. (4/500)
The hemodynamic and right ventricular volumetric effects of disopyramide were investigated in patients with tetralogy of Fallot (TF). Intracardiac pressure and oxygen saturation were measured, before and after intravenous administration of disopyramide (2 mg/kg) in 7 patients who had not had previous surgery. Right ventricular volume and the diameter of its outflow tract were analyzed in these 7 and in a further 4 patients with a previous shunt. Aortic oxygen saturation increased from 90.4+/-7.5 (mean+/-SD) to 94.1+/-5.5% (p<0.05) with an increase in pulmonary blood flow and pressure. The systolic pressure gradient between the main pulmonary artery and the right ventricle decreased from 59+/-8 to 42+/-9 mmHg (p<0.01). Aortic pressure fell from 77+/-5 to 67+/-4 mmHg (p<0.05). Systemic vascular resistance increased from 15.3+/-2.2 to 19.4+/-3.3 u x m2 (p<0.05). Pulmonary vascular resistance remained unchanged. The diastolic and systolic diameter indices of the right ventricular outflow tract increased from 17.8+/-3.8 to 20.5+/-3.4 and from 6.5+/-3.0 to 10.4+/-2.2 mm/m2, respectively (p<0.01), whereas the right ventricular ejection fraction decreased. Disopyramide improves systemic oxygen saturation in patients with TF through its negative inotropic action on the right ventricle. (+info)The myocardial profile of the cytosolic isozymes of creatine kinase is apparently not related to cyanosis in congenital heart disease. (5/500)
BACKGROUND: CKMB, the cardiac-specific heterodimer of cytosolic creatine-kinase (CK), is developmentally and physiologically regulated, tissue hypoxia being a proposed regulator. In patients with cyanotic heart disease the myocardium is perfused with partially saturated blood. We questioned whether the myocardium of cyanotic subjects contains higher proportions of CKMB. MATERIALS AND METHODS: CK activity, the distribution of cytosolic CK isozymes, activity of lactic dehydrogenase (LDH), and tissue protein content were determined in obstructive tissues removed at corrective surgery of patients with congenital heart defects. Cyanotic (n = 13) and acyanotic (n = 12) subjects were compared. RESULTS: In cyanotic and acyanotic patients, CK activity was 8.4 +/- 0.6 and 7.6 +/- 0.6 IU/mg protein and the proportion of CKMB was 21 +/- 1.4 and 22 +/- 2. 0% (mean +/- S.E.M), respectively. In the two groups of patients, the activity related to the B subunit corresponded to the steady-state level of the CKBmRNA. The tissue content of protein and the activities of CK and LDH were similar in cyanotic and acyanotic subjects and increased with the age. CONCLUSIONS: The lack of difference in CKMB distribution between the cyanotic and acyanotic patients may either indicate that hypooxygenation is not a regulator of CK isozyme expression, or may be attributed to the already high proportion of this isozyme in hypertrophied, obstructive tissues. Recruitment of additional CKMB, in the cyanotic hearts, may thus not be required. (+info)Accuracy of electrocardiographic and echocardiographic indices in predicting life threatening ventricular arrhythmias in patients operated for tetralogy of Fallot. (6/500)
OBJECTIVE: To validate the accuracy of the prognostic significance of non-invasive clinical diagnostic indices as predictors of sustained ventricular tachycardia (sVT) or fibrillation (VF) in patients undergoing repair for tetralogy of Fallot. METHODS: One way analysis of variance and pairwise comparison of the values with the Bonferroni correction, logistic multivariate analysis, and ordinal logistic analysis were used to study quantitative electrocardiographic and echocardiographic variables in 66 patients who had undergone surgery for tetralogy of Fallot by ventriculotomy at a mean (SD) age of 11.8 (9.5) years. The mean (SD) period of follow up was 16.1 (5.7) years after surgery. RESULTS: Four groups of patients were identified by ECG and 24 hour Holter monitoring: 19 (28.7%) without ventricular arrhythmias, 34 (51.5%) with minor ventricular arrhythmias, seven (10.6%) with non-sustained ventricular tachycardia (nsVT), and six (9.0%) with sVT or VF. One way analysis indicated significant differences in QT dispersion (QTd) and end diastolic volume of the right ventricle (EDVRV) among the groups. Univariate logistic analysis showed EDVRV, QTd, and QRS duration to be significantly associated with sVT or VF. Stepwise multivariate analysis and ordinal logistic analysis showed QTd to be preferable to QRS duration as an indicator, because it was unrelated to EDVRV, and was capable of separating different probability curves for nsVT as opposed to sVT or VF. CONCLUSIONS: Stratification of patients undergoing corrective surgery for tetralogy of Fallot and at risk of life threatening arrhythmias is possible by simple and inexpensive means, which provide sensitive and specific indices. (+info)Reduced heart rate variability following repair of tetralogy of Fallot. (7/500)
OBJECTIVE: To examine autonomic function as assessed by heart rate variability in patients 10 or more years after repair of tetralogy of Fallot, and to relate this to cardiac structure, function, and electrocardiographic indices. METHODS: Heart rate variability was measured by standard time domain techniques on a 24 hour Holter ECG in 28 patients, aged 12 to 34 years (mean 19.5), who had undergone repair of tetralogy of Fallot at least 10 years previously. Echocardiography was performed to assess left ventricular size and function, right ventricular size and pressure, and any proximal pulmonary arterial stenosis. Right ventricular function was evaluated by radionuclide scan. QRS duration, QT interval, and QT dispersion were measured on a standard 12 lead ECG. Measurements of heart rate variability were compared with values from 28 age matched healthy controls (mean age 19.9 years). Interrelations between variables were assessed using Pearson correlation coefficients and stepwise regression analysis. RESULTS: Heart rate variability was reduced, compared with values for age matched normal controls, in 12 of the 28 patients. Reduced heart rate variability was associated with increased age, increased right ventricular size and pressure, and widening of the QRS complex. CONCLUSIONS: Reduced heart rate variability is a feature following repair of tetralogy of Fallot. It is associated with increasing age, impaired right ventricular haemodynamics, and widening of the QRS complex. Under these circumstances, reduced heart rate variability may be a marker for deteriorating right ventricular function. Increased QRS duration has been identified as a risk factor for sudden death following repair of tetralogy of Fallot, and impaired cardiac autonomic control may be one of the mechanisms involved. (+info)Tetralogy of Fallot in the fetus: findings at targeted sonography. (8/500)
OBJECTIVES: To evaluate the findings of tetralogy of Fallot in various fetal sonographic views. METHODS: We reviewed the fetal sonograms and medical records of 20 fetuses with prenatal diagnosis of tetralogy of Fallot. We analyzed the indications for targeted sonography, the abnormalities seen in various sonographic views, the postnatal echocardiographic and angiographic findings and autopsy findings. RESULTS: The most common indication for targeted sonography was an abnormal (n = 12) or inadequate (n = 3) finding on sonographic screening in which the abnormality was most frequently found on the three-vessel view (n = 9). The key pathological features of tetralogy of Fallot were uniformly demonstrated in the ventricular outflow tract, three-vessel and short-axis views. The ductus arteriosus was small in 70% of cases and not identifiable in the remaining fetuses. In three of six fetuses with no identifiable ductus, the ductus was shown to be absent at autopsy. The direction of ductal flow was variable. CONCLUSION: The key features of tetralogy of Fallot were always demonstrable in the ventricular outflow tract, three-vessel and short-axis views. The most common reason for referral was the abnormal three-vessel view. (+info)Treatment of Tetralogy Of Fallot, Tetrology Of Fallot, Tetralogy Of Fallot Definition, Causes, Risk Factors, Symptoms,...
Tetralogy of Fallot synonyms, tetralogy of Fallot antonyms - FreeThesaurus.com
Relation of right ventricular mechanics to exercise tolerance in children after tetralogy of Fallot repair<...
General Anatomy/Tetralogy of Fallot - Wikibooks, open books for an open world
Anchor balloon, buddy wire, and wire and sheath techniques to deploy percutaneous pulmonary valves in tetralogy of fallot...
DNA methylation status of NKX2-5, GATA4 and HAND1 in patients with tetralogy of fallot | BMC Medical Genomics | Full Text
Long-Term Evaluation of Tetralogy Patients with Pulmonary Valvular Insufficiency Resulting from Outflow-Patch Correction Across...
Does Pharmacological Therapy Still Play a Role in Preventing Sudden Death in Surgically Treated Tetralogy of Fallot? | Bentham...
NOREPINEPHRINE AND CYANOTIC ATTACKS IN FALLOTS TETRALOGY | Heart
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Fallots tetralogy رباعي فالوت - العيادة السورية - دليل المعلومات الطبي
Right Ventricular Diastolic Function in Children With Pulmonary Regurgitation After Repair of Tetralogy of Fallot: Volumetric...
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Tetralogy of Fallot
What Is Tetralogy of Fallot? at the National Institutes of Health Understanding your child's heart: Tetralogy of Fallot by the ... Tetralogy of Fallot (TOF), formerly known as Steno-Fallot tetralogy, is a congenital heart defect characterized by four ... including tetralogy of Fallot). Below are the four heart malformations that present together in tetralogy of Fallot: There is ... Trilogy of Fallot Congenital rubella syndrome Lehn M. "Fallot's tetralogy". Whonamedit?. Archived from the original on 3 ...
Helen B. Taussig
While this was going on, Taussig observed that infants with cyanotic heart defects such as Tetralogy of Fallot or pulmonary ... Neill, C A; Clark, E B (1994). "Tetralogy of Fallot. The first 300 years". Texas Heart Institute Journal. 21 (4): 272-279. ISSN ... Taussig diagnosed her with Tetralogy of Fallot, a diagnosis which meant that without intervention she certainly would not ... and is used in the care of patients with Tetralogy of Fallot, pulmonary atresia, and more rare and complex abnormalities. At ...
Heart
Tetralogy of Fallot). Some congenital heart defects allow blood that is low in oxygen that would normally be returned to the ...
Multan Institute of Cardiology
Repair of Fallot's Tetralogy • PDA • Surgery for Coarctation of aorta • PA banding • Right Heart bypass in uni ventricular ... "Surgical repair of Tetralogy of Fallot in children and adult patients". Archived from the original on 17 October 2013. ... Tariq Waqar, Yasir Khan, Anjum Jalal Surgical repair of Tetralogy of Fallot in children and adult patients: A Retrospective ...
List of OMIM disorder codes
WNT3 Tetralogy of Fallot; 187500; GDF1 Tetralogy of Fallot; 187500; JAG1 Tetralogy of Fallot; 187500; ZFPM2 Tetrology of Fallot ...
Blue baby syndrome
In tetralogy of Fallot, episodes in which infants become cyanotic are called tet spells, typically occurring during feeding or ... Tetralogy of Fallot is the most common cyanotic cardiac heart defect. Methemoglobinemia is considered to be rare, with acquired ... "Orphanet: Tetralogy of Fallot". www.orpha.net. Retrieved 20 November 2019. CDC (19 November 2019). "Congenital Heart Defects - ... Death can occur when levels reach 70%. The first successful operation to treat blue baby syndrome caused by Tetralogy of Fallot ...
Sussex Spaniel
A heart condition uncommon to the breed is tetralogy of Fallot, which is more common in the Keeshond and English Bulldog breeds ... "What is Tetralogy of Fallot?". Canine Inherited Disorders Database. 2001-10-30. Retrieved 2009-11-23. Lundgren, Becky. " ...
Squatting position
"Tetralogy of Fallot - Symptoms and causes". Mayo Clinic. Retrieved 21 August 2021. Murakami T (2002). "Squatting: the ... Guntheroth WG, Mortan BC, Mullins GL, Baum D. Am "Venous return with knee-chest position and squatting in tetralogy of Fallot ... Toddlers and older children with the congenital heart disease tetralogy of Fallot will often instinctively squat during a "tet ...
Homeobox protein Nkx-2.5
Goldmuntz E, Geiger E, Benson DW (November 2001). "NKX2.5 mutations in patients with tetralogy of fallot". Circulation. 104 (21 ...
Subclavian steal syndrome
Another example is Blalock-Taussig anastomosis for treatment of tetralogy of Fallot. The procedure involves dividing the ... Vertebrobasilar ischemia after correction of tetralogy of Fallot". Stroke. 15 (2): 359-62. doi:10.1161/01.str.15.2.359. PMID ... Kurlan, R; Krall, RL; Deweese, JA (March 1984). "Vertebrobasilar ischemia after total repair of tetralogy of Fallot: ...
Trilogy of Fallot
The first two of these are also found in the more common tetralogy of Fallot. However, the tetralogy has a ventricular septal ... CDC (2019-11-19). "Congenital Heart Defects - Facts about Tetralogy of Fallot , CDC". Centers for Disease Control and ... The Trilogy of Fallot also called Fallot's trilogy is a rare congenital heart disease consisting of the following defects: ... It is named in honor of its discoverer: Etienne Fallot. "Fallot trilogy (Concept Id: C0041022) - MedGen - NCBI". www.ncbi.nlm. ...
Phonocardiogram
"Phonocardiogram in adult patients with tetralogy of Fallot". Journal of Cardiology. 65 (1): 82-86. doi:10.1016/j.jjcc.2014.03. ...
Riaz Haider
Twelve year follow-up of Tetralogy of Fallot after surgical Correction of Fallots Tetralogy in Childhood. Brit. H.J. 34, 2,205 ... "Results of total correction of the tetralogy of Fallot. Long-term haemodynamic evaluation at rest and during exercise". Heart. ... "Results of total correction of the tetralogy of Fallot. Long-term haemodynamic evaluation at rest and during exercise". Heart. ... "Twelve years follow-up after surgical correction of Fallot's tetralogy in childhood". British Heart Journal. 34 (2): 205-206. ...
PITX2
In Congenital Heart Disease, heterozygous mutations in Pitx2 have been involved in the development of Tetralogy of Fallot, ... Sun, Y (February 15, 2016). "PITX2 loss-of-function mutation contributes to tetralogy of Fallot". Gene. 577 (2): 258-264. doi: ...
Absent pulmonary valve syndrome
It is sometimes considered a variant of Tetralogy of Fallot. Nölke, Lars; Azakie, Anthony; Anagnostopoulos, Petrous V.; ...
Right atrial enlargement
... pulmonary stenosis or Tetralogy of Fallot i.e. congenital diseases; chronic lung disease, such as cor pulmonale. Other ...
Tinman (gene)
These include atrial and ventricular septal defects and tetralogy of Fallot. Abnormal placental expression of Nkx2.5 has been ...
Dennis McEldowney
Auto-biographical in nature, it described how he dealt with being an invalid due to having a Tetralogy of Fallot. This book won ... He was born with a congenital heart defect, Tetralogy of Fallot. Owing to this heart condition, McEldowney was an invalid until ...
MYL4
Auckland LM, Lambert SJ, Cummins P (November 1986). "Cardiac myosin light and heavy chain isotypes in tetralogy of Fallot". ... tetralogy of Fallot. Altered ALC-1 expression is also altered in other congenital heart diseases, Double outlet right ventricle ...
Pulmonary atresia with ventricular septal defect
The condition has been called a severe form of Tetralogy of Fallot. If deformed blood vessels coming from the thoracic aorta ... and tetralogy of Fallot (TOF)". FEBS Open Bio. 11 (2): 375-385. doi:10.1002/2211-5463.13044. PMC 7876499. PMID 33211401. Shi X ... "A review of the options for treatment of major aortopulmonary collateral arteries in the setting of tetralogy of Fallot with ... and reoperations after repair of tetralogy of Fallot with pulmonary atresia". The Journal of Thoracic and Cardiovascular ...
SNX8
A candidate gene for 7p22 cardiac malformations including tetralogy of fallot". American Journal of Medical Genetics Part A. ... "7p22.3 microdeletion disrupting SNX8 in a patient presenting with intellectual disability but no tetralogy of Fallot". American ... dysmorphic features and cardiac malformations encompassing tetralogy of Fallot, one of the most common cyanotic congenital ... "Correspondence regarding SNX8 haploinsufficiency and its potential for cardiac anomalies including tetralogy of Fallot". ...
Panangipalli Venugopal
Pseudoaneurysm of ascending aorta 35 years after repair of tetralogy of Fallot". Interactive Cardiovascular and Thoracic ...
Townes-Brocks syndrome
Heart abnormalities, including tetralogy of fallot and defects of the ventricular septum. Hand and foot abnormalities, such as ...
HAND2
Tetralogy of Fallot experienced significantly decreased Hand2 interactions with other key developmental genes such as GATA4 and ... "A novel HAND2 loss-of-function mutation responsible for tetralogy of Fallot". International Journal of Molecular Medicine. 37 ( ...
John W. Kirklin
The Tetralogy of Fallot from a surgical viewpoint, with Robert B. Karp, Philadelphia: Saunders (1970), ISBN 978-0721654744 ... Kirklin's modifications and team work also allowed repairs of tetralogy of Fallot. Varying in style and character, Lillehei and ... ASDs and tetralogy of Fallot. 30 survived and 20 were still alive 50 years later. Following the experimental trial in dogs, ...
JAG1
Notch signaling Alagille syndrome Autosomal dominant Haploinsufficiency Tetralogy of fallot In situ hybridization Conditional ... there is a subset of individuals with JAG1 mutations who present with tetralogy of fallot/pulmonary stenosis that do not show ... mutations in patients with tetralogy of Fallot or pulmonic stenosis". Hum. Mutat. 31 (5): 594-601. doi:10.1002/humu.21231. PMC ...
Down syndrome
Other problems that may occur include tetralogy of Fallot and patent ductus arteriosus. People with Down syndrome have a lower ...
1q21.1 duplication syndrome
In case of a duplication of GJA5 tetralogy of Fallot is more common. In case of a deletion other congenital heart diseases than ... tetralogy of Fallot are more common. A. Ploeger; 'Towards an integration of evolutionary psychology and developmental science: ...
1q21.1 deletion syndrome
In case of a duplication of GJA5 tetralogy of Fallot is more common. In case of a deletion other congenital heart diseases than ... tetralogy of Fallot are more common. "Overview: 1q21.1 microdeletion syndrome". Genetic and Rare Diseases Information Center ( ...
John Maurice Hardman Campbell
"Results of pulmonary valvotomy and infundibular resection in 100 Cases of Fallot's tetralogy". Br Med J. 2 (4880): 111-122. doi ...
Pulmonary agenesis
... tetralogy of Fallot and anomalies of the great vessels. Although pulmonary agenesis, aplasia and hypoplasia are lethal ...
Ectopia cordis
Intracardiac defects Atrial septal defect Ventricular septal defect Tetralogy of Fallot Tricuspid atresia Double outlet right ...
List of circulatory system conditions
Double aortic arch Double inlet left ventricle Double outlet right ventricle Ebstein's anomaly GUCH Tetralogy of Fallot (ToF) ...
Percutaneous pulmonary valve implantation
Tetralogy of Fallot, or persistent truncus arteriosus. PPVI can also be used to replace dysfunctional artificial heart valves. ...
C. Walton Lillehei
These operations included the first repairs of the atrioventricular canal and tetralogy of Fallot. In July of that year, a ... had begun successfully performing surgery on the great vessels around the heart to relieve the symptoms of tetralogy of Fallot ...
Henry F. Gilbert
He had a congenital heart condition known as Tetralogy of Fallot, and his case was published by White and Sprague in the ...
TOF
... mass spectrometry uses the time of flight of an ion in the gas phase to resolve its mass-to-charge ratio Tetralogy of Fallot, a ...
Congenital heart defect
Such defects include persistent truncus arteriosus, total anomalous pulmonary venous connection, tetralogy of Fallot, ... tetralogy of Fallot in 13% of cases), liver, eyes, face, and bones. Though less than 1% of all cases, where no defects are ... and tetralogy of Fallot are the most common congenital heart defects seen in the VACTERL association. Less common defects in ... Tetralogy of Fallot (ToF) Pentalogy of Cantrell Shone's syndrome/ Shone's complex / Shone's anomaly CHD may require surgery and ...
Fetal alcohol spectrum disorder
Ventricular septal defect, atrial septal defect, tetralogy of Fallot, coarctation of the aorta, and/or cardiac rhythm ...
List of fetal abnormalities
... valves Renal agenesis Rh incompatibility Sacrococcygeal teratoma Spina bifida Spinal dysraphism Syndactyly Tetralogy of Fallot ...
Russell M. Nelson
In March 1956, he performed the first successful pediatric cardiac operation at the SLGH, a total repair of tetralogy of Fallot ...
Cri du chat syndrome
... tetralogy of Fallot). Infertility is not associated with Cri du chat. It has also been observed that people with the condition ...
Atrial fibrillation
In particular, people who had atrial septal defects, Tetralogy of Fallot, or Ebstein's anomaly, and those who underwent the ...
MFSD6L
A disease associated with the MFSD6L gene is the Tetralogy of Fallot, which is a series of four congenital heart defects that ...
Major aortopulmonary collateral artery
Management of Tetralogy of Fallot with pulmonary atresia - contains angiographic images of MAPCAs. Maeda, Eriko; Masaaki ... Though it is usually associated with congenital heart diseases with decreased pulmonary blood flow like tetralogy of Fallot or ... Pulmonary atresia with ventricular septal defect (or Tetralogy of Fallot with pulmonary atresia) will result in the development ... Interactive videogame graphic showing repair of tetralogy of Fallot with pulmonary atresia - from Lucile Packard Children's ...
Double outlet right ventricle
... physiology resembles Tetralogy of Fallot in other forms of DORV, blood from both ventricles is substantially mixed in the RV, ... physiology resembles Tetralogy of Fallot DORV is treated with surgery.[citation needed] DORV affects between 1% and 3% of ...
DiGeorge syndrome
... tetralogy of Fallot, and ventricular septal defect) Cyanosis (bluish skin due to poor circulation of oxygen-rich blood) Palatal ... truncus arteriosus and tetralogy of Fallot) Abnormal facies Thymic aplasia or hypoplasia Cleft palate Hypocalcemia/ ...
Atrioventricular septal defect
Certain complications such as tetralogy of Fallot or highly unbalanced flow across the common AV valve can increase risk ...
Jane Somerville
... whose achievements in treating tetralogy of Fallot with the Blalock Taussig shunt, transformed the lives of children. The once ...
1p36 deletion syndrome
... patients may have congenital heart defects ranging from cardiac septal defects to valvular anomalies and tetralogy of Fallot. ...
List of ICD-9 codes 740-759: congenital anomalies
... and anomalies of cardiac septal closure 745.0 Common truncus 745.1 Transposition of great vessels 745.2 Tetralogy of fallot ...
List of syndromes
... syndrome Tension myositis syndrome Terson syndrome Testicular dysgenesis syndrome Tetra-amelia syndrome Tetralogy of Fallot ...
Protein signalling in heart development
... aortic and pulmonary valve stenosis or tetralogy of fallot. The heart valves are formed. Defects in this process are known as ...
Tetralogy of Fallot - Care at Mayo Clinic - Mayo Clinic
Tetralogy of Fallot care at Mayo Clinic. Your Mayo Clinic team. Mayo Clinic doctors treat people with all types of heart ... Innovative research. Mayo Clinic doctors conduct research in new diagnostic tests and treatments for tetralogy of Fallot and ... Advanced diagnosis and treatment. Mayo cardiovascular surgeons have experience and expertise treating tetralogy of Fallot and ... Each Mayo Clinic location offers care for adults with tetralogy of Fallot and other congenital heart diseases. ...
Tetralogy of Fallot | NCBDDD | CDC
Tetralogy of Fallot is in fact a spectrum of diseases and might be clinically severe or mild, depending on the degree of ... Key findings in tetralogy of Fallot:. *Stenosis at or below the pulmonary valve, or pulmonary valve atresia (absent pulmonary ... Tetralogy of Fallot - Documentation Checklist. Describe in detail the clinical and echocardiographic findings: *Anatomy - ... Tetralogy of Fallot is a structural heart anomaly characterized clinically by cyanosis, and anatomically by an obstructed right ...
Tetralogy of Fallot: MedlinePlus Medical Encyclopedia
Tetralogy of Fallot is a type of congenital heart defect. Congenital means that it is present at birth. ... Tet; TOF; Congenital heart defect - tetralogy; Cyanotic heart disease - tetralogy; Birth defect - tetralogy ... Tetralogy of Fallot is rare, but it is the most common form of cyanotic congenital heart disease. It occurs equally as often in ... Surgery to repair tetralogy of Fallot is done when the infant is very young, typically before 6 months of age. Sometimes, more ...
Tetralogy of Fallot - Mayo Clinic
Tetralogy of Fallot (TOF) in Adults: Practice Essentials, Background, Anatomy
... because tetralogy of Fallot results in an inadequate flow of blood to the lungs for oxygenation (right-to-left shunt) (see the ... Tetralogy of Fallot (TOF) is one of the most common congenital heart disorders (CHDs). This condition is classified as a ... See also Tetralogy of Fallot With Pulmonary Stenosis, Tetralogy of Fallot With Pulmonary Atresia, and Tetralogy of Fallot With ... encoded search term (Tetralogy of Fallot (TOF) in Adults) and Tetralogy of Fallot (TOF) in Adults What to Read Next on Medscape ...
Tetralogy of Fallot With Absent Pulmonary Valve: Background, Pathophysiology, Etiology
... with absent pulmonary valve is a rare congenital anomaly characterized by features of tetralogy of Fallot with either ... See Tetralogy of Fallot, Tetralogy of Fallot With Pulmonary Stenosis, and Tetralogy of Fallot With Pulmonary Atresia for more ... encoded search term (Tetralogy of Fallot With Absent Pulmonary Valve) and Tetralogy of Fallot With Absent Pulmonary Valve What ... However, tetralogy of Fallot with absent pulmonary valve is rare, with approximately 3% of patients with tetralogy of Fallot ...
Tetralogy of Fallot: Aidan's Story | Children's Hospital of Philadelphia
From his prenatal diagnosis of tetralogy of Fallot, to treatment after birth and follow-up care, Aidan has benefited from the ... Tetralogy of Fallot (TOF) is a congenital heart defect that can be diagnosed either before or after a baby is born. Learn more ... The diagnosis: Tetralogy of Fallot (TOF). Maria was 20 weeks pregnant when an ultrasound showed an irregularity in her babys ... When Ben was 2-years-old, he had open heart surgery to repair tetralogy of Fallot. Today, he is a happy and energetic boy. ...
Tetralogy of Fallot - Pediatrics - Merck Manuals Professional Edition
Tetralogy of Fallot - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical ... Tetralogy of Fallot (see figure Tetralogy of Fallot Tetralogy of Fallot ) accounts for 7 to 10% of congenital heart anomalies. ... Pathophysiology of Tetralogy of Fallot The ventricular septal defect in tetralogy of Fallot is often described as a ... Tetralogy of Fallot By Lee B. Beerman , MD, Childrens Hospital of Pittsburgh of the University of Pittsburgh School of ...
What is Tetralogy of Fallot
Tetralogy of Fallot (ToF) is a heart defect that features 4 main defects. Less blood will flow to the lungs so oxygen levels in ... Tetralogy of Fallot (ToF) What is Tetralogy of Fallot (ToF)?. The heart is made up of 4 chambers. The lower two equal sized ... Tetralogy of Fallot is a heart condition that is named after the French doctor Etienne-Louis Arthur Fallot who described it in ... Babies born with Tetralogy of Fallot, often abbreviated to ToF, have less blood flowing to the lungs, meaning that the level of ...
Tetralogy of Fallot (TOF)
Tetralogy of Fallot is 4 congenital heart defects. This means that your child is born with them. These 4 problems occur ... Tetralogy of Fallot (TOF). What is tetralogy of Fallot?. Tetralogy of Fallot (TOF) is a set of 4 congenital heart defects that ... Key points about tetralogy of Fallot. * Tetralogy of Fallot is a set of 4 congenital heart defects. Children are born with this ... What causes tetralogy of Fallot?. Genes and family history may play a part in TOF. It may also be caused by Down syndrome or ...
Tetralogy of Fallot in Cats: A Rare but Serious Birth Defect
... ... "Tetralogy of Fallot." Vetstream.com. Web.. *DJ Brockman, DE Holt, JW Gaynor, and TE Theman. "Long-term Palliation of Tetralogy ... Tetralogy of Fallot is the most common of rare diseases that produce cyanosis as a main finding. It is said to make up 6% of ... Symptoms of Tetralogy of Fallot. While uncommon in dogs it is even less frequently reported in cats. Most cases are first seen ...
What you should know about tetralogy of Fallot and surgery
Can you explain the condition and treatment? Can I expect him to live a normal life? ANSWER: Tetralogy of Fallot is a ... Tetralogy of Fallot causes oxygen-poor blood to flow out of the heart and to the rest of the body, often resulting in babies ... Most tetralogy of Fallot children generally do well after surgery. The blood flow to the lungs is restored, and they are no ... Most people with tetralogy of Fallot will need a pulmonary valve replacement at some time in the future. The age when this ...
Outlier-based identification of copy number variations using targeted resequencing in a small cohort of patients with tetralogy...
The anatomy of tetralogy of Fallot with pulmonary stenosis.<...
Anderson, R. H., & Jacobs, M. L. (2008). The anatomy of tetralogy of Fallot with pulmonary stenosis. Cardiology in the young, ... The anatomy of tetralogy of Fallot with pulmonary stenosis. Cardiology in the young. 2008 Dec;18 Suppl 3:12-21. doi: 10.1017/ ... Anderson, Robert H. ; Jacobs, Marshall L. / The anatomy of tetralogy of Fallot with pulmonary stenosis. In: Cardiology in the ... Anderson, RH & Jacobs, ML 2008, The anatomy of tetralogy of Fallot with pulmonary stenosis., Cardiology in the young, vol. 18 ...
UMN Medical School Researchers Study the Long-Term Effects of Tetralogy of Fallot | Medical School - University of Minnesota
This project was in collaboration with researchers at Emory University.Tetralogy of Fallot is a birth defect that affects ... School researchers evaluated the long-term survival rate of patients with a very serious cardiac defect called tetralogy of ... Tetralogy of Fallot is a birth defect that affects normal blood flow through the heart. This heart defect can cause reduced ... Infants with tetralogy of Fallot can have a bluish-looking skin color, called cyanosis, because their blood doesnt carry ...
External Compression of the Abdominal Aorta Reversing Tetralogy of Fallot Cyanotic Crisis | Anesthesiology | American Society...
External Compression of the Abdominal Aorta Reversing Tetralogy of Fallot Cyanotic Crisis Philippe L. Baele, M.D.; Philippe L. ... Anesthetic Management of Tetralogy of Fallot with Absent Pulmonary Valve Anesthesiology (May 1989) ... External Compression of the Abdominal Aorta Reversing Tetralogy of Fallot Cyanotic Crisis. Anesthesiology 1991; 75:146-148 doi ...
Tetralogy of Fallot (Fallot Tetralogy): Symptoms, Diagnosis and Treatment - Symptoma
Tetralogy of Fallot (Fallot Tetralogy): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. ... Tetralogy of Fallot (TOF) is a congenital disorder of the heart. It is made up of four anatomical malformations, hence the ... Fallot Tetralogy Tetralogy of Fallot (TOF) is a congenital disorder of the heart. It is made up of four anatomical ... Tetralogy of Fallot is a common congenital heart disorder. It is a cyanotic heart disease and is the most common cause of blue ...
ESC 365 - Right ventricular apical bulging in repaired tetralogy of Fallot with severe pulmonary regurgitation
Exploring the cause of conduction delays in patients with repaired Tetralogy of Fallot<...
Exploring the cause of conduction delays in patients with repaired Tetralogy of Fallot. EP Europace. 2021 Mar 1;23:I105-I112. ... Exploring the cause of conduction delays in patients with repaired Tetralogy of Fallot. In: EP Europace. 2021 ; Vol. 23. pp. ... Exploring the cause of conduction delays in patients with repaired Tetralogy of Fallot. / Verzaal, N.J.; Masse, S.; Downar, E. ... N2 - Aim Cardiac dyssynchrony in patients with repaired Tetralogy of Fallot (rToF) has been attributed to right bundle branch ...
Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot - Wellcome Centre for Human...
Prenatal images of left hemitruncus in tetralogy of fallot with an absent pulmonary valve<...
Tsukimori, K, Morihana, E, Fusazaki, N & Fujita, Y 2013, Prenatal images of left hemitruncus in tetralogy of fallot with an ... Tsukimori, K., Morihana, E., Fusazaki, N., & Fujita, Y. (2013). Prenatal images of left hemitruncus in tetralogy of fallot with ... Prenatal images of left hemitruncus in tetralogy of fallot with an absent pulmonary valve. Pediatric Cardiology. 2013 Jun;34(5 ... Prenatal images of left hemitruncus in tetralogy of fallot with an absent pulmonary valve. In: Pediatric Cardiology. 2013 ; Vol ...
Tetralogy of Fallot With Pulmonary Stenosis Differential Diagnoses
... with pulmonary stenosis is the common form of tetralogy of Fallot, and it is the focus of this article. Tetralogy of Fallot is ... encoded search term (Tetralogy of Fallot With Pulmonary Stenosis) and Tetralogy of Fallot With Pulmonary Stenosis What to Read ... Direct vision intracardiac surgical correction of the tetralogy of Fallot, pentalogy of Fallot, and pulmonary atresia defects; ... Treatment of Fallots tetralogy in children under 1 year of age]. Rozhl Chir. 1962 Mar. 41:181-3. [QxMD MEDLINE Link]. ...
IMSEAR at SEARO: Tetralogy of Fallot--clinical profile.
4mos Tetralogy of Fallot, s/p BT shunt | NIH 3D Print Exchange
Tetralogy of Fallot - Ethos Veterinary Health
Our Little Braveheart | Surviving Tetralogy of Fallot
As with most Tetralogy of Fallot patients, he has leakage in his pulmonary valve. Weve always been told that its possible he ... I will say that I am very grateful that there is a generation of adults ahead of Jake who are living with Tetralogy of Fallot. ... Tagged as CHD, CHD Awareness Week, congenital heart defect, congenital heart disease, heart defect, Tetralogy of Fallot. ... It was then that we discovered Jake had a congenital heart defect called Tetralogy of Fallot (TOF). ...
Tetralogy of Fallot | Cyanotic Heart Disease | Geeky Medics
A summary of Tetralogy of Fallot including pathophysiology, risk factors, clinical features (symptoms, signs), key ... Tetralogy of Fallot diagram.. Development of Tetralogy of Fallot. The development of Tetralogy of Fallot begins in utero and is ... Causes of Tetralogy of Fallot. There is no single cause for Tetralogy of Fallot. Instead, the development of TOF is ... A, W., Tetralogy of Fallot- antenatal. Case Study Radiopaedia 2020.. *Lee, W., et al., Tetralogy of Fallot: prenatal diagnosis ...
Duodenal atresia tetralogy of Fallot - Rare Psychiatry News
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct. ...
Tetralogy of Fallot in Children | NYU Langone Health
Pediatric Congenital Heart Program at Hassenfeld Childrens Hospital at NYU Langone treat children who have tetralogy of Fallot ... Treatment for Tetralogy of Fallot. Babies diagnosed with tetralogy of Fallot require a series of heart surgeries, referred to ... Diagnosing Tetralogy of Fallot. Tetralogy of Fallot is often detected before birth during a prenatal ultrasound or fetal ... Tetralogy of Fallot in Children. Facebook. Opens in a new tab Twitter. Opens in a new tab ...
plastic injection mold defects images tetralogy of fallot brain
Tetralogy of Fallot (TOF) , Johns Hopkins Medicine. Tetralogy of Fallot (TOF) Tetralogy of Fallot (TOF) is a combination of ... Tetralogy of Fallot (TOF) , Johns Hopkins Medicine. Tetralogy of Fallot (TOF) Tetralogy of Fallot (TOF) is a combination of ... Tetralogy of Fallot , NCBDDD , CDC. Mar 30, 2021·Tetralogy of Fallot is a structural heart anomaly characterized clinically by ... Congenital Heart Defects: Tetralogy of Fallot - Childrens Health .... The four problems caused by tetralogy of Fallot include ...
DiagnosisCase of tetralogy of falCoarctation of thFindings in tetralogyFeatures of tetralogyEtienne-Louis Arthur FallotChild with tetralogyAorticSymptomsAbsent pulmonary valveCyanoticDefectsAdultsAtrialPatientsSeptalPediatricAnomaliesCyanosisCardiologyFlowing to the lungsPulmonary valve replacementRepairTransannularRight ventricleAdulthoodAnomalyCongenital cardiacOxygenRefersBabiesHeart surgeryUncommonClinical trialsPrenatalSurgeryBloodGeneticAnatomyBirthOutflowOutcomes
Diagnosis1
- A nurse is caring for an infant with a diagnosis of tetralogy of Fallot. (medihealthwriter.com)
Case of tetralogy of fal1
- We report a case of tetralogy of Fallot with pulmonary atresia, total anomalous pulmonary venous return, complete atrioventricular septal defects, absence of central pulmonary arteries and a double aortic arch. (researchwithrutgers.com)
Coarctation of th1
- 10 microns and sulfur dioxide with coarctation of the aorta, tetralogy of Fallot and atrial septal defects. (cdc.gov)
Findings in tetralogy1
- Anatomic findings in tetralogy of Fallot are depicted. (medscape.com)
Features of tetralogy2
- Tetralogy of Fallot (TOF) with absent pulmonary valve is a rare congenital anomaly characterized by features of tetralogy of Fallot with either rudimentary ridges or the complete absence of pulmonic valve tissue and usually with a hypoplastic pulmonary valve annulus. (medscape.com)
- Drawing showing absence of the pulmonary valve with features of tetralogy of Fallot. (medscape.com)
Etienne-Louis Arthur Fallot1
- The syndrome is named for French physician Etienne-Louis Arthur Fallot, M.D., who first published a description of the defect in 1888. (observerxtra.com)
Child with tetralogy2
- If a child with tetralogy of Fallot becomes blue, immediately place the child on their side or back and put the knees up to the chest. (medlineplus.gov)
- Compared with a normal heart, the heart in a child with tetralogy of Fallot has several changes that affect blood flow and make it difficult for blood to receive enough oxygen. (nyulangone.org)
Aortic3
- Tetralogy of Fallot and right-sided aortic arch configuration was noted. (springeropen.com)
- The aortic valve overrides the interventricular septum in this heart with tetralogy of Fallot. (ipccc.net)
- Postoperative transcatheter intervention was needed in 2 patients (1.8%): one for dilatation of aortic arch stenosis after repair of hypoplastic left heart syndrome with equine pericardium and one for dilatation of pulmonary artery branches after repair of tetralogy of Fallot using bovine pericardium. (autotissue.de)
Symptoms4
- [ 1 , 2 ] Some patients who never underwent surgery for mild tetralogy during childhood may present as adults with a variety of symptoms, and other patients who may only have had a palliative procedure (eg, shunt placement) can also present as adults. (medscape.com)
- What are the symptoms of tetralogy of Fallot? (brighamandwomens.org)
- Wide variation in the basic anatomic morphology, pathophysiology, clinical signs and symptoms, and surgical methods of therapy is noted for tetralogy of Fallot (TOF). (medscape.com)
- There was also a background of tetralogy of Fallot(TOF) with symptoms of chronic breathlessness and palpitations. (springeropen.com)
Absent pulmonary valve2
- However, tetralogy of Fallot with absent pulmonary valve is rare, with approximately 3% of patients with tetralogy of Fallot having the absent pulmonary valve syndrome. (medscape.com)
- Etiologic factors for tetralogy of Fallot (TOF) with absent pulmonary valve are not known in most cases. (medscape.com)
Cyanotic6
- Tetralogy of Fallot is rare, but it is the most common form of cyanotic congenital heart disease. (medlineplus.gov)
- Tetralogy of Fallot is the most common cause of cyanotic heart disease and may occur at a rate of 1-3 cases per 1000 live births. (medscape.com)
- We evaluated our outlier- based method in comparison to the CNV calling tool CoNIFER using eight HapMap exome samples and subsequently applied both methods to targeted resequencing data of patients with Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease. (mdc-berlin.de)
- Stenting of the right ventricular outflow tract in the high-risk infant with cyanotic teratology of Fallot. (medscape.com)
- Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease (CHD) presenting after the neonatal period 1,2 . (geekymedics.com)
- Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease and the population of ToF repair survivors is growing rapidly. (biomedcentral.com)
Defects13
- People with tetralogy of Fallot are more likely to also have other congenital defects. (medlineplus.gov)
- Children with tetralogy of Fallot are more likely to have chromosome disorders, such as Down syndrome, Alagille syndrome, and DiGeorge syndrome (a condition that causes heart defects, low calcium levels, and poor immune function). (medlineplus.gov)
- Tetralogy of Fallot is a combination of four congenital heart defects. (mayoclinic.org)
- Tetralogy of Fallot (TOF) is a set of 4 congenital heart defects that occur together. (brighamandwomens.org)
- Doctors at Johns Hopkins were the first to devise a procedure to place a shunt to bypass cardiac defects related to tetralogy of Fallot and redirect unoxygenated blood directly to the lungs. (observerxtra.com)
- Therefore, Tetralogy of Fallot is characterised by four defects. (geekymedics.com)
- Lesions include Tetralogy of Fallot, atrial septal defect and ventricular septal defects. (geekymedics.com)
- Babies diagnosed with tetralogy of Fallot require a series of heart surgeries , referred to as complete repair, to treat the defects associated with this condition. (nyulangone.org)
- Elastron TPE- plastic injection mold defects images tetralogy of fallot brain ,Increase the melt temperature: If two different flows meet together and are colder than normal, weld lines will appear. (isarkarinokari.com)
- Tetralogy of Fallot (TOF) Tetralogy of Fallot (TOF) is a combination of four congenital (present at birth) heart defects that affect infants and children. (isarkarinokari.com)
- The most common congenital defects in horses are ventricular septal defect, patent ductus arteriosus, tetralogy of Fallot, and tricuspid dysplasia. (msdvetmanual.com)
- Direct vision intracardiac surgical correction of the Tetralogy of Fallot, Pentalogy of Fallot and pulmonary atresia defects. (ijsurgery.com)
- Tetralogy of Fallot is a rare combination of four defects that required her to undergo surgery as a baby and to be examined regularly by a cardiologist. (empoweredtoserve.org)
Adults5
- Doctors in the Center for Congenital Heart Disease at Mayo Clinic's campus in Minnesota treat children and adults with tetralogy of Fallot and other congenital heart diseases. (mayoclinic.org)
- Each Mayo Clinic location offers care for adults with tetralogy of Fallot and other congenital heart diseases. (mayoclinic.org)
- About half of all tetralogy of Fallot patients develop heart rhythm problems as adults, and they may need a pacemaker or defibrillator. (observerxtra.com)
- Arya S, Kovach J, Singh H, Karpawich PP. Arrhythmias and sudden death among older children and young adults following tetralogy of Fallot repair in the current era: are previously reported risk factors still applicable? (medscape.com)
- I will say that I am very grateful that there is a generation of adults ahead of Jake who are living with Tetralogy of Fallot. (ourlittlebraveheart.com)
Atrial3
- To compare trans-atrial/Trans-pulmonary and trans-annular/trans-ventricular techniques of surgical correction of tetralogy of fallot. (pafmj.org)
- Fifteen years' experience of Tetralogy of fallot corrections at AFIC-NIHD indicates that Trans-atrial / Trans-pulmonary approach is more beneficial to patients due to high survival rate, less morbidity, less hospital stay and an early discharge. (pafmj.org)
- Right atrial approach for surgical correction of tetrology of Fallot. (ijsurgery.com)
Patients15
- The mortality rate in untreated patients reaches 50% by age 6 years, but in the present era of cardiac surgery, children with simple forms of tetralogy of Fallot enjoy good long-term survival with an excellent quality of life. (medscape.com)
- Although the classic boot-shaped heart ( coeur en sabot ) is the hallmark of the disorder in infants, this shape of the heart may not be seen in adult patients. (medscape.com)
- MINNEAPOLIS, MN- December 19, 2018 - University of Minnesota Medical School researchers evaluated the long-term survival rate of patients with a very serious cardiac defect called tetralogy of Fallot. (umn.edu)
- In a cohort study funded by a grant from the National Heart, Lung, and Blood Institute (NHLBI), researchers studied nearly 3,300 patients who had surgery which repaired their tetralogy of Fallot. (umn.edu)
- Researchers found the overall survival of patients in the database of tetralogy of Fallot surgery was almost 95 percent over 25 years, but there were survival differences among patients. (umn.edu)
- Aim Cardiac dyssynchrony in patients with repaired Tetralogy of Fallot (rToF) has been attributed to right bundle branch block (RBBB), fibrosis and/or the patches that are inserted during repair surgery. (maastrichtuniversity.nl)
- Shah RR, Poommipanit P, Law MA, Amin Z. Anchor balloon, buddy wire, and wire and sheath techniques to deploy percutaneous pulmonary valves in tetralogy of fallot patients. (medscape.com)
- Nollert G, Fischlein T, Bouterwek S, Bohmer C, Klinner W, Reichart B. Long-term survival in patients with repair of tetralogy of Fallot: 36-year follow-up of 490 survivors of the first year after surgical repair. (medscape.com)
- Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort. (medscape.com)
- As with most Tetralogy of Fallot patients, he has leakage in his pulmonary valve. (ourlittlebraveheart.com)
- The aim of the study was to assess the hemodynamic impact and prognostic relevance of RV pressure load in a population of patients following tetralogy of Fallot repair. (thechipnetwork.org)
- Relation between right ventricular enlargement, QRS duration, and right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation after surgical repair. (ijsurgery.com)
- Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. (ijsurgery.com)
- Background: Ventricular tachycardia (VT) in patients following tetralogy of Fallot (TOF) repair is challenging to map because of the presence of scar, patch material, and hemodynamic residua of surgery. (elsevier.com)
- Background: Studies suggest that right ventricular (RV) fibrosis is associated with RV remodeling and long-term outcomes in patients with tetralogy of Fallot (TOF). (mssm.edu)
Septal7
- Tetralogy of Fallot (TOF) (pronounced te-tral-uh-jee of Fal-oh), one of the most common congenital heart disorders, comprises right ventricular (RV) outflow tract obstruction (RVOTO) (infundibular stenosis), ventricular septal defect (VSD), aorta dextroposition (overriding aorta), and RV hypertrophy (see the image below). (medscape.com)
- Tetralogy of Fallot (TOF) consists of a malalignment ventricular septal defect (VSD), infundibular pulmonary stenosis, overriding aorta, and right ventricular hypertrophy (RVH). (medscape.com)
- Tetralogy of Fallot consists of 4 features: a large ventricular septal defect, right ventricular outflow tract obstruction and pulmonic valve stenosis, right ventricular hypertrophy, and over-riding of the aorta. (merckmanuals.com)
- The ventricular septal defect in tetralogy of Fallot is often described as a malalignment type, since the conal septum is displaced anteriorly. (merckmanuals.com)
- Other conditions to consider when evaluating a patient with suspected Tetralogy of Fallot with pulmonary stenosis include acute anemia, asthma and reactive airway disease, bacteremia and sepsis, cardiogenic shock, Ebstein malformation of the tricuspid valve, pseudotruncus arteriosus, pulmonary atresia, septic shock, and ventricular septal defect (VSD). (medscape.com)
- Home 1 / IPCCC Structure 2 / 01.01.20 - Atrioventricular septal defect and tetralogy of Fallot. (ipccc.net)
- IPCCC Definition A congenital cardiac malformation with both an atrioventricular septal defect (atrioventricular canal defect) and tetralogy of Fallot. (ipccc.net)
Pediatric6
- Mayo Clinic cardiologists, pediatric cardiologists and cardiac surgeons have extensive experience diagnosing and treating people with tetralogy of Fallot and other congenital heart diseases. (mayoclinic.org)
- After the fetal echocardiography, pediatric cardiologist Shobha Natarajan, MD , confirmed that the baby did have tetralogy of Fallot. (chop.edu)
- Long-term Outcomes of Tetralogy of Fallot: A Study From the Pediatric Cardiac Care Consortium," published in JAMA Cardiology, is one of several papers published looking at pediatric mortality. (umn.edu)
- Our team at the Pediatric Congenital Heart Program , part of Hassenfeld Children's Hospital at NYU Langone , includes pediatric cardiac surgeons, cardiologists, anesthesiologists, and cardiothoracic nurse practitioners who are experts in the care of children who have tetralogy of Fallot. (nyulangone.org)
- All babies with tetralogy of Fallot are closely monitored by our team at the Pediatric Congenital Heart Program, who develop a treatment plan based on your baby's individual needs. (nyulangone.org)
- As they grow, children with tetralogy of Fallot are closely followed by our team at the Pediatric Congenital Heart Program, and as they get older, through the Congenital Heart Transition Program . (nyulangone.org)
Anomalies1
- BAE is effective even in presence of underlying vascular anomalies such as Fallot of Tetralogy. (springeropen.com)
Cyanosis4
- In some children with unrepaired tetralogy of Fallot, most often those several months up to 2 years of age, sudden episodes of profound cyanosis and hypoxia (hypercyanotic or "tet" spells) may occur, which may be lethal. (merckmanuals.com)
- Tetralogy of Fallot is the most common of rare diseases that produce cyanosis as a main finding. (pethealthnetwork.com)
- Infants with tetralogy of Fallot can have a bluish-looking skin color, called cyanosis, because their blood doesn't carry enough oxygen. (umn.edu)
- Fallot A. Contribution to the pathological anatomy of the blue disease (cardiac cyanosis), Marseille. (ijsurgery.com)
Cardiology1
- As a result, many children with repaired tetralogy of Fallot survive into adulthood and are seen at cardiology clinics. (medscape.com)
Flowing to the lungs1
- Babies born with Tetralogy of Fallot, often abbreviated to ToF, have less blood flowing to the lungs, meaning that the level of oxygen in their blood is low. (tinytickers.org)
Pulmonary valve replacement1
- Most people with tetralogy of Fallot will need a pulmonary valve replacement at some time in the future. (observerxtra.com)
Repair12
- Cardiovascular surgeons have experience performing intracardiac repair surgery - a procedure that improves and redirects blood flow in the heart so that blood flows in the correct direction - to treat tetralogy of Fallot. (mayoclinic.org)
- Surgery to repair tetralogy of Fallot is done when the infant is very young, typically before 6 months of age. (medlineplus.gov)
- The patient's oxygenation status, serum lactate levels, and base excess value appear to be prognostic markers for mortality in those undergoing surgical repair of tetralogy of Fallot. (medscape.com)
- Effect of transannular patching on outcome after repair of tetralogy of Fallot. (medscape.com)
- Low incidence of arrhythmias in the right ventricular infundibulum sparing approach to tetralogy of Fallot repair. (medscape.com)
- Gellis L, Banka P, Marshall A, Emani S, Porras D. Transcatheter balloon dilation for recurrent right ventricular outflow tract obstruction following valve-sparing repair of tetralogy of Fallot. (medscape.com)
- Right ventricular outflow tract stenting in tetralogy of Fallot infants with risk factors for early primary repair. (medscape.com)
- Hill G. Repair and follow-up of Tetralogy of Fallot with pulmonary stenosis. (medscape.com)
- Background: Recent data have demonstrated that overall mortality and adverse events are not significantly different for primary repair (PR) and staged repair (SR) approaches to management of neonates with symptomatic tetralogy of Fallot (sTOF). (uab.edu)
- Fatal arrhythmia late after repair of tetralogy of Fallot (TOF) is related to right ventricular volume load caused by pulmonary valve regurgitation (PR). (jspccs.jp)
- Transatrial transpulmonary repair of tetrology of Fallot. (ijsurgery.com)
- Early results after transatrial/ transpulmonary repair of tetralogy of Fallot. (ijsurgery.com)
Transannular2
- The objective of this study was to evaluate the early and mid-term outcome of total correction of tetralogy of Fallot (TOF) done through transatrial approach avoiding ventriculotomy with or without transannular patching. (ijsurgery.com)
- Tetralogy of Fallot: transannular and right ventricular patching equally affect late functional status. (ijsurgery.com)
Right ventricle1
- In some cases of Tetralogy of Fallot, the pulmonic stenosis is so great, that the easiest path for the blood to take is from the right ventricle, through the hole in the septum to the left ventricle and out the aorta. (ethosvet.com)
Adulthood1
- Most people with tetralogy of Fallot are diagnosed in infancy, but in rare cases the condition is not detected until adulthood. (nyulangone.org)
Anomaly1
- The term "tetralogy" refers to the four main features of the anomaly, but it is actually due to a single defect. (observerxtra.com)
Congenital cardiac1
- Tetralogy of Fallot is an uncommon congenital cardiac abnormality that can affect both cats and dogs. (ethosvet.com)
Oxygen5
- Pulse oximetry, available in many nurseries, is a helpful initial tool to screen for low blood oxygenation, though not specifically for tetralogy of Fallot as there are many causes of low oxygen saturation in the newborn, including sepsis, lung disease and a variety of CHDs. (cdc.gov)
- Tetralogy of Fallot causes low oxygen levels in the blood. (medlineplus.gov)
- Some babies with Tetralogy may also have "spells" - caused by a sudden drop in the oxygen level of the blood. (tinytickers.org)
- Tetralogy of Fallot causes oxygen-poor blood to flow out of the heart and to the rest of the body, often resulting in babies having blue-tinged skin because their blood doesn't carry enough oxygen. (observerxtra.com)
- Our doctors are among the most skilled in the country at treating babies born with tetralogy of Fallot, a congenital heart defect that has an impact on the way blood moves from the heart to the lungs and makes it difficult for blood to receive enough oxygen. (nyulangone.org)
Refers2
- Tetralogy" refers to the number 4. (brighamandwomens.org)
- The word 'tetralogy' refers to something made up of four parts. (geekymedics.com)
Babies2
- Most babies diagnosed with Tetralogy of Fallot will not need immediate treatment so can be discharged as normal, soon after birth. (tinytickers.org)
- There are tetralogy babies who have sufficient blood flow to the lungs, and these babies are commonly termed "pink tets. (observerxtra.com)
Heart surgery3
- Three days later, Aidan had open heart surgery to treat his tetralogy of Fallot. (chop.edu)
- Due to the issues caused by tetralogy of Fallot, your grandson will need heart surgery, though the timing will depend on the specifics of his situation. (observerxtra.com)
- Beau Casson: Tetralogy of Fallot, Heart Surgery and Meeting Ajmal Shahzad! (wordpress.com)
Uncommon1
- An uncommon cardiac defect called "Tetralogy of Fallot" is a devastating birth defect of cats 1 . (pethealthnetwork.com)
Clinical trials1
- Mayo Clinic doctors conduct research in new diagnostic tests and treatments for tetralogy of Fallot and conduct clinical trials. (mayoclinic.org)
Prenatal1
- Tetralogy of Fallot is often detected before birth during a prenatal ultrasound or fetal echocardiogram , a scan that provides a detailed picture of your child's beating heart in the womb. (nyulangone.org)
Surgery2
- However, it is important to understand that corrective surgery for tetralogy of Fallot performed in childhood is not curative surgery. (medscape.com)
- Most tetralogy of Fallot children generally do well after surgery. (observerxtra.com)
Blood2
- Several cases of polycythemia (excess red blood cells) have been associated with Tetralogy of Fallot. (pethealthnetwork.com)
- Tetralogy of Fallot is a birth defect that affects normal blood flow through the heart. (umn.edu)
Genetic2
- A common genetic condition with tetralogy of Fallot (seen in about 15-20 % of cases) is deletion 22q11, a condition in which a small part of chromosome 22 is missing. (cdc.gov)
- However, Tetralogy of Fallot is associated with various genetic conditions . (geekymedics.com)
Anatomy2
- The anatomy of tetralogy of Fallot with pulmonary stenosis. (elsevier.com)
- Anderson RH, Weinberg PM. The clinical anatomy of tetralogy of Fallot. (ijsurgery.com)
Birth1
- He was diagnosed with Tetralogy of Fallot antenatally and was born at term (a normal vaginal birth). (symptoma.com)
Outflow1
- Tetralogy of Fallot is in fact a spectrum of diseases and might be clinically severe or mild, depending on the degree of obstruction in the right ventricular outflow tract. (cdc.gov)
Outcomes1
- Challenges and outcomes of pregnancy in an uncorrected Tetralogy of Fallot with pulmonary atresia and major aorta-pulmonary collateral arteries (MAPCA): a case report. (bvsalud.org)