OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth CareGeographicals
TaxusPaclitaxelDrug-Eluting StentsCoronary RestenosisCardiovascular AgentsPlant PoisoningTubulin ModulatorsProsthesis DesignChromium AlloysAngioplasty, Balloon, CoronaryPrince Edward IslandNew South WalesTurner SyndromeFraudEmbryologyDocumentationSanitary EngineeringBathing BeachesHawksEncyclopedias as TopicParisRestaurantsWaterPublic-Private Sector PartnershipsCoxsackie and Adenovirus Receptor-Like Membrane ProteinInvestmentsAngioplasty, BalloonAdenoviridaeReceptors, VirusCardiac CatheterizationFloridaDeerNitrogen CompoundsPhysalisEntomophthoralesPinusNigeriaTransportationAppointments and SchedulesAmyloid beta-Protein PrecursorPrenatal CareObstetrics and Gynecology Department, HospitalAutomobile DrivingCitiesTravelEuropean UnionAzospirillum brasilenseArchaeoglobalesAutomobilesLoveBaltimorePhenylketonuriasWindNeonatal ScreeningBlood Specimen Collection
Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).Paclitaxel: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.Drug-Eluting Stents: Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.Cardiovascular Agents: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.Plant Poisoning: Poisoning by the ingestion of plants or its leaves, berries, roots or stalks. The manifestations in both humans and animals vary in severity from mild to life threatening. In animals, especially domestic animals, it is usually the result of ingesting moldy or fermented forage.Tubulin Modulators: Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Chromium Alloys: Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Prince Edward Island: An island in the Gulf of St. Lawrence constituting a province of Canada in the eastern part of the country. It is very irregular in shape with many deep inlets. Its capital is Charlottetown. Discovered by the French in 1534 and originally named Ile Saint-Jean, it was renamed in 1799 in honor of Prince Edward, fourth son of George III and future father of Queen Victoria. (From Webster's New Geographical Dictionary, 1988, p981 & Room, Brewer's Dictionary of Names, 1992, p433)New South Wales: A state in southeastern Australia. Its capital is Sydney. It was discovered by Captain Cook in 1770 and first settled at Botany Bay by marines and convicts in 1788. It was named by Captain Cook who thought its coastline resembled that of South Wales. (From Webster's New Geographical Dictionary, 1988, p840 & Room, Brewer's Dictionary of Names, 1992, p377)Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.Fraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Embryology: The study of the development of an organism during the embryonic and fetal stages of life.Documentation: Systematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature (From ALA Glossary of Library and Information Science, 1983). It often involves authenticating or validating information.Sanitary Engineering: A branch of engineering concerned with the design, construction, and maintenance of environmental facilities conducive to public health, such as water supply and waste disposal.Bathing Beaches: Beaches, both natural and man-made, used for bathing and other activities.Hawks: Common name for many members of the FALCONIFORMES order, family Accipitridae, generally smaller than EAGLES, and containing short, rounded wings and a long tail.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)ParisRestaurantsWater: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Public-Private Sector Partnerships: An organizational enterprise between a public sector agency, federal, state or local, and a private sector entity. Skills and assets of each sector are shared to deliver a service or facility for the benefit or use of the general public.Coxsackie and Adenovirus Receptor-Like Membrane Protein: An Ig superfamily transmembrane protein that localizes to junctional complexes that occur between ENDOTHELIAL CELLS and EPTHELIAL CELLS. The protein may play a role in cell-cell adhesion and is the primary site for the attachment of ADENOVIRUSES during infection.Investments: Use for articles on the investing of funds for income or profit.Angioplasty, Balloon: Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.Adenoviridae: A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.Receptors, Virus: Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.FloridaDeer: The family Cervidae of 17 genera and 45 species occurring nearly throughout North America, South America, and Eurasia, on most associated continental islands, and in northern Africa. Wild populations of deer have been established through introduction by people in Cuba, New Guinea, Australia, New Zealand, and other places where the family does not naturally occur. They are slim, long-legged and best characterized by the presence of antlers. Their habitat is forests, swamps, brush country, deserts, and arctic tundra. They are usually good swimmers; some migrate seasonally. (Walker's Mammals of the World, 5th ed, p1362)Nitrogen Compounds: Inorganic compounds that contain nitrogen as an integral part of the molecule.Physalis: A plant genus of the family SOLANACEAE. Members contain physalin and withangulatin.Entomophthorales: An order of fungi comprising mostly insect pathogens, though some infect mammals including humans. Strict host specificity make these fungi a focus of many biological control studies.Pinus: A plant genus in the family PINACEAE, order Pinales, class Pinopsida, division Coniferophyta. They are evergreen trees mainly in temperate climates.Nigeria: A republic in western Africa, south of NIGER between BENIN and CAMEROON. Its capital is Abuja.Transportation: The means of moving persons, animals, goods, or materials from one place to another.Appointments and Schedules: The different methods of scheduling patient visits, appointment systems, individual or group appointments, waiting times, waiting lists for hospitals, walk-in clinics, etc.Amyloid beta-Protein Precursor: A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.Prenatal Care: Care provided the pregnant woman in order to prevent complications, and decrease the incidence of maternal and prenatal mortality.Obstetrics and Gynecology Department, Hospital: Hospital department responsible for the administration and management of services provided for obstetric and gynecologic patients.Automobile Driving: The effect of environmental or physiological factors on the driver and driving ability. Included are driving fatigue, and the effect of drugs, disease, and physical disabilities on driving.Cities: A large or important municipality of a country, usually a major metropolitan center.Travel: Aspects of health and disease related to travel.European Union: The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)Azospirillum brasilense: A species of motile, free-living, gram-negative bacteria that occur in the soil. They are aerobic or microaerophilic and are sometimes capable of nitrogen fixation.Archaeoglobales: An order of extremely thermophilic, sulfate-reducing archaea, in the kingdom EURYARCHAEOTA. The single family Archaeoglobaceae contains one genus ARCHAEOGLOBUS.Automobiles: A usually four-wheeled automotive vehicle designed for passenger transportation and commonly propelled by an internal-combustion engine using a volatile fuel. (Webster, 1973)Love: Affection; in psychiatry commonly refers to pleasure, particularly as it applies to gratifying experiences between individuals.BaltimorePhenylketonurias: A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).Wind: The motion of air relative to the earth's surface.Neonatal Screening: The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.

New taxane diterpenoid from seed of the Chinese yew, Taxus yunnanensis. (1/79)

A novel taxane diterpenoid with a rearranged 5/7/6-membered ring system was isolated from seeds of the Chinese yew, Taxus yunnanensis. Its structure was established as 9alpha,13alpha-diacetoxy-10beta-benzoxy-5alpha- cinnamoyl-11(1 5-->1)-abeotaxa-4(20),11-dien-15-ol on the basis of a spectroscopic analysis. Its relative stereochemistry is proposed from the results of NOESY experiments.  (+info)

Two novel taxane diterpenoids from the needles of Japanese yew, Taxus cuspidata. (2/79)

Two novel taxane diterpenoids were isolated from the needles of Japanese yew, Taxus cuspidata, and their structures were determined to be lbeta-hydroxy-7beta-acetoxytaxinine (1) and lbeta,7beta-dihydroxytaxinine (2) on the basis of spectral analyses including 2D-NMR studies.  (+info)

Reversal of P-glycoprotein and multidrug-resistance protein-mediated drug resistance in KB cells by 5-O-benzoylated taxinine K. (3/79)

A newly synthesized taxoid originally from the Japanese yew Taxus cuspidata, 5-O-benzoylated taxinine K (BTK) was examined for its ability to reverse P-glycoprotein (P-gp) and multidrug resistance protein (MRP)-mediated multidrug resistance. BTK reversed the resistance to paclitaxel, doxorubicin (ADM), and vincristine (VCR) of KB-8-5 and KB-C2 cells that overexpress P-gp by directly interacting with P-gp. BTK also moderately reversed the resistance to ADM of KB/MRP cells that overexpress MRP. However, BTK neither inhibited the transporting activity of MRP nor reduced intracellular glutathione levels in KB/MRP cells. BTK shifted the distribution of ADM in KB/MRP cells from punctate cytoplasmic compartments to the nucleoplasm and cytoplasm by inhibiting acidification of cytoplasmic organelles. These two functions of BTK make it able to reverse both P-gp- and MRP-mediated MDR. BTK in combination with ADM should be useful for treating patients with tumors that overexpress both P-gp and MRP.  (+info)

Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthase. (4/79)

BACKGROUND: The committed step in the biosynthesis of the anticancer drug taxol in yew (Taxus) species is the cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene. The enzyme taxadiene synthase catalyzes this complex olefin cation cyclization cascade involving the formation of three rings and three stereogenic centers. RESULTS: Recombinant taxadiene synthase was incubated with specifically deuterated substrates, and the mechanism of cyclization was probed using MS and NMR analyses of the products to define the crucial hydrogen migration and terminating deprotonation steps. The electrophilic cyclization involves the ionization of the diphosphate with closure of the A-ring, followed by a unique intramolecular transfer of the C11 proton to the re-face of C7 to promote closure of the B/C-ring juncture, and cascade termination by proton elimination from the beta-face of C5. CONCLUSIONS: These findings provide insight into the molecular architecture of the first dedicated step of taxol biosynthesis that creates the taxane carbon skeleton, and they have broad implications for the general mechanistic capability of the large family of terpenoid cyclization enzymes.  (+info)

New 11(15-->1)abeotaxane, 11(15-->1),11(10-->9)bisabeotaxane and 3,11-cyclotaxanes from Taxus yunnanensis. (5/79)

Chemical examination of the seeds of Chinese yew, Taxus yunnanensis Cheng et L. K. Fu resulted in the isolation of an 11(15-->1)abeotaxane, an 11(15-->1), 11(10-->9)bisabeotaxane and two 3,11-cyclotaxanes. The structures of these new taxoids were established as 13alpha-acetoxy-5alpha-cinnamoyloxy-11(15-->1)abeotaxa-4(20),11-diene-9alpha,10be ta,15-triol (1), 20-acetoxy-2alpha-benzoyloxy-4alpha, 5alpha, 7beta, 9alpha, 13alpha-pentahydroxy-11(15-->1), 11(10-->9) bisabeotax-11-eno-10,15-lactone (2), 2alpha,10beta-diacetoxy-5alpha-cinnamoyloxy-9alpha-hydroxy-3,11 -cyclotax-4(20)-en-13-one (3) and 10beta-acetoxy-2alpha,5alpha,9alpha-trihydroxy-3,11-cyclotax-4(20)-en-13-one (4) on the basis of spectral analyses.  (+info)

Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase. (6/79)

A central feature in the biosynthesis of Taxol is oxygenation at multiple positions of the taxane core structure, reactions that are considered to be mediated by cytochrome P450-dependent monooxygenases. A PCR-based differential display-cloning approach, using Taxus (yew) cells induced for Taxol production, yielded a family of related cytochrome P450 genes, one of which was assigned as a taxane 10 beta-hydroxylase by functional expression in yeast. The acquired clones that did not function in yeast were heterologously expressed by using the Spodoptera fugiperda-baculovirus-based system and were screened for catalytic capability by using taxa-4(20),11(12)-dien-5 alpha-ol and its acetate ester as test substrates. This approach allowed identification of one of the cytochrome P450 clones (which bore 63% deduced sequence identity to the aforementioned taxane 10 beta-hydroxylase) as a taxane 13 alpha-hydroxylase by chromatographic and spectrometric characterization of the corresponding recombinant enzyme product. The demonstration of a second relevant hydroxylase from the induced family of cytochrome P450 genes validates this strategy for elucidating the oxygenation steps of taxane diterpenoid (taxoid) metabolism. Additionally, substrate specificity studies with the available cytochrome P450 hydroxylases now indicate that there is likely more than one biosynthetic route to Taxol in yew species.  (+info)

New taxane diterpenoids from the roots of Taiwanese Taxus mairei. (7/79)

Five new taxane diterpenoids, taxumairols G (1), H (2), I (3), J (4), and L (5) were isolated from extracts of the roots of Taiwanese Taxus mairei (LEMEE & LEVL.) S. Y. Hu. Compounds 1-4 belong to the new 11(15-->1)-abeo-taxene system, having a tetrahydrofuran ring along carbons C-2, C-3, C-4 and C-20. Compounds 3 and 4 contain an isopropenyl group at C-1 while compounds 1 and 2 are attached with a benzoxyl group at C-15. The structures of compounds 1-5 were determined on the basis of two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond correlation (HMBC), and nuclear Overhauser effect spectroscopy (NOESY) experiments.  (+info)

The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus. (8/79)

The formation of several acyl groups and an amide group of Taxol is catalyzed by regioselective CoA thioester-dependent acyltransferases. Several full-length acyltransferase sequences, obtained from a cDNA library constructed from mRNA isolated from Taxus cuspidata cells induced for Taxol production with methyl jasmonate, were individually expressed in Escherichia coli, from which a cDNA clone encoding a 3'-N-debenzoyl- 2'-deoxytaxol N-benzoyltransferase was identified. This recombinant enzyme catalyzes the stereoselective coupling of the surrogate substrate N-debenzoyl-(3'RS)-2'-deoxytaxol with benzoyl-CoA to form predominantly one 3'-epimer of 2'-deoxytaxol. The product 2'-deoxytaxol was confirmed by radio-HPLC,(1)H-NMR, and chemical ionization-MS. This enzymatic reaction constitutes the final acylation in the Taxol biosynthetic pathway. The full-length cDNA coding for the N-benzoyltransferase has an ORF of 1,323 nucleotides and encodes a 441-residue protein with a calculated molecular weight of 49,040. The recombinant enzyme expressed in E. coli has a pH optimum at 8.0, a k(cat) approximately 1.5 +/- 0.3 s(-1) and K(m) values of 0.42 mM and 0.40 mM for the N-deacylated taxoid and benzoyl-CoA, respectively. In addition to improving the production yields of Taxol in genetically engineered host systems, this enzyme provides a means of attaching modified aroyl groups to taxoid precursors for the purpose of improving drug efficacy.  (+info)

Taxus cuspidata Columnaris - Plant FinderTaxus cuspidata 'Columnaris' - Plant Finder
Taxus cuspidata, commonly known as Japanese yew, is a broad-columnar needled evergreen tree or multistemmed shrub that is native to Korea, China, Russia and Japan. In its native habitat, it will grow to as much as 30-50 tall. In cultivation it will grow much smaller, particularly if regularly pruned. It features linear, spiny-tipped, dark green needles (to 1" long). Leaves are often tinged yellow beneath. Foliage may turn reddish-brown or yellow in winter. Scaly, reddish brown bark. Although classified as a conifer, female yews (plants are dioecious) do not produce cones, but instead produce red, ornamentally-attractive, berry-like fruits, each having a single seed almost completely surrounded by a fleshy red aril. Birds will feed on the berry-like fruits and help spread plants to other locations ...
The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear...The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear...
Gymnosperms represent five of the six lineages of seed plants. However, most sequenced plant mitochondrial genomes (mitogenomes) have been generated for angiosperms, whereas mitogenomic sequences have been generated for only six gymnosperms. In particular, complete mitogenomes are available for all major seed plant lineages except Conifer II (non-Pinaceae conifers or Cupressophyta), an important lineage including six families, which impedes a comprehensive understanding of the mitogenomic diversity and evolution in gymnosperms. Here, we report the complete mitogenome of Taxus cuspidata in Conifer II. In comparison with previously released gymnosperm mitogenomes, we found that the mitogenomes of Taxus and Welwitschia have lost many genes individually, whereas all genes were identified in the mitogenomes of Cycas, Ginkgo and Pinaceae. Multiple tRNA genes and introns also have been lost in some lineages of gymnosperms, similar to the pattern observed in angiosperms. In general, gene clusters could be less
Taxine - WikipediaTaxine - Wikipedia
Taxine is a toxic alkaloid compound present in the Yew tree, Taxus baccata. It is composed of more than seven alkaloids, the main constituents being taxine A and taxine B; the other components are their derivatives, such as 2-deacetyltaxine A, isotaxine B and 1-deoxytaxine B. This substance is characterized by high melting and boiling point. Taxine is soluble in chloroform and alcohol, and insoluble in water or oil. Taxine can be found in Taxus species: Taxus cuspidata, T. baccata (English yew), Taxus x media, Taxus canadensis, Taxus floridana and Taxus brevifolia (Pacific or western yew). All of these species contain taxine in every part of the plant except in the aril, the fleshy covering of the seeds (berries). Each species contains a different amount of taxine concentration, which leads to varying toxicities within the genus. This is the case of the Taxus brevifolia or Pacific yew and the Taxus baccata (English yew); T. baccata contains high taxine concentration, which leads to a high ...
Taxus × media Citation - Plant FinderTaxus × media 'Citation' - Plant Finder
Taxus x media is a hybrid designation for a large number of shrubby, often wide-spreading crosses of English yew (Taxus baccata) and Japanese yew (Taxus cuspidata). These hybrids are noted for combining the ornamental excellence of English yew with the winter hardiness of Japanese yew. Although primarily resembling T. cuspitata in appearance, the various hybrid cultivars can vary considerably in size and character. Height ranges from 2-20 tall depending on the cultivar. Two ranked, pointed, oblong to needle-like, olive to dark green leaves are attractive year round. Bark is scaly brown. Plants are dioecious (separate male and female plants). Female plants produce red, berry-like fruits instead of cones. Each fruit has a single seed almost completely surrounded by a fleshy red aril. All parts of this plant are poisonous if ingested ...
First Report of Leaf Blight of Japanese Yew Caused by Pestalotiopsis microspora in KoreaFirst Report of Leaf Blight of Japanese Yew Caused by Pestalotiopsis microspora in Korea
Worldwide, Japanese yew (Taxus cuspidata Sieb. & Zucc.) is a popular garden tree, with large trees also being used for timber. In July 2012, leaf blight was observed on 10% of Japanese yew seedling leaves planted in a 500-m2 field in Andong, Gyeongsangbuk-do Province, South Korea. Typical symptoms included small, brown lesions that were first visible on the leaf margin, which enlarged and coalesced into the leaf becoming brown and blighted. To isolate potential pathogens from infected leaves, small sections of leaf tissue (5 to 10 mm2) were excised from lesion margins. Eight fungi were isolated from eight symptomatic trees, respectively. These fungi were hyphal tipped twice and transferred to potato dextrose agar (PDA) plates for incubation at 25°C. After 7 days, the fungi produced circular mats of white aerial mycelia. After 12 days, black acervuli containing slimy spore masses formed over the mycelial mats. Two representative isolates were further characterized. Their conidia were straight or ...
Taxus Baccata. - A DICTIONARY OF PRACTICAL MATERIA MEDICA By John Henry CLARKE, M.D. Presented by M di-TTaxus Baccata. - A DICTIONARY OF PRACTICAL MATERIA MEDICA By John Henry CLARKE, M.D. Presented by M di-T
Presented by M di-T Taxus Baccata.. Taxus baccata. Yew. N. O. Conifer . Tincture of the fresh young shoots. (Tincture of the berries.). Clinical.─Ciliary neuralgia. Cystitis. Digestion, too rapid. Dysuria. Ear, polypus of. Eruptions. Fainting. Gout. Hair, falling out. Headache, with photopsia. Heart, affections of. Kidneys, affections of. Knees, abscess of. Lachrymation. Nose, eruption on. Rheumatism. Purpura. Spermatorrh a. Strangury. Vision, dim.. Characteristics.─The poisonous properties of the Yew have been recognised and disputed from ancient times. Gerarde says that in his schooldays he and his companions ate their fill of the berries of the Yew and slept not only under its shade, but on its branches, without any ill effect. But there is plenty of evidence on the other side. Recently (Med. Press, May 29, 1901), a patient of Mullingar Asylum died suddenly from eating Yew leaves. Some years ago a correspondence in the Times brought to light instances of the lethal effects of Yew leaves ...
Spatial genetic structure of Taxus baccata L. in the western Mediterranean Basin: Past and present limits to gene movement over...Spatial genetic structure of Taxus baccata L. in the western Mediterranean Basin: Past and present limits to gene movement over...
TY - JOUR. T1 - Spatial genetic structure of Taxus baccata L. in the western Mediterranean Basin: Past and present limits to gene movement over a broad geographic scale. AU - González-Martínez, Santiago C.. AU - Dubreuil, M.. AU - Riba, M.. AU - Vendramin, G. G.. AU - Sebastiani, F.. AU - Mayol, M.. PY - 2010/6/1. Y1 - 2010/6/1. N2 - English yew (Taxus baccata L., Taxaceae), a Tertiary relict, provides a seminal example of a widespread albeit locally endangered (often close to extinction) tree species. In order to gain detailed insights into the evolutionary dynamics of the species on a broad geographical scale, over 1000 trees from 91 populations of English yew in the western Mediterranean were analyzed using seven nuclear microsatellite markers. Our results revealed contrasting patterns of genetic structure at different spatial scales: genetic variation was highly structured at the local scale, while only a low proportion of the observed variation was attributed to regional differences. We ...
Expression profiling of genes involved in Taxuyunnanine C biosynthesis in cell suspension cultures of Taxus chinensis by...Expression profiling of genes involved in Taxuyunnanine C biosynthesis in cell suspension cultures of Taxus chinensis by...
TY - JOUR. T1 - Expression profiling of genes involved in Taxuyunnanine C biosynthesis in cell suspension cultures of Taxus chinensis by repeated elicitation with a newly synthesized jasmonate and sucrose feeding. AU - Gao, Ming-Bo. AU - Zhang, Wei. AU - Li, Xingtai. AU - Ruan, Cheng-jiang. AU - Fan, Shengdi. PY - 2011/1. Y1 - 2011/1. N2 - Taxus suspension cell culture has the potential to provide a sustainable source of anticancer drug paclitaxel (Taxol ® ) and other taxoids. In the cell culture of Taxus chinensis, Taxuyunnanine C (Tc) is the primary taxoid. To design a rational strategy for redirecting the precursor fluxes from other taxoids into paclitaxel production, we employed Real-time Quantitative PCR (RQ-PCR) to understand the dynamic profiling of key biosynthetic pathway genes of palcitaxel and taxoids during the culture process. Six genes (TASY, TDAT, T5αH, TαH, T10βH and T14βH) were quantified under the process condition of double elicitation by 2, 3-dihydroxylpropanyl jasmonate ...
Taxus media ( Moon Yew ) | Backyard GardenerTaxus media ( Moon Yew ) | Backyard Gardener
This dense erect-rounded form also has upright shoots and branches. In general, form is broadly pyramidal with a central leader. Similar to Taxus cuspidata, the Anglojap Yew has olive green branchlets which do not turn brown the second year. Bud scales are blunt and leaves are two-ranked. Thrives in sandier soil that
Walter Pall Bonsai Adventures: March 2014Walter Pall Bonsai Adventures: March 2014
Japanese yew, Taxus cuspidata, imported from Japan in 2013. I acquired the tree in may 2013 and started to redesign immediately. I somehow felt that it was a good tree, but not really great. to me it was too nice, too symmetrical, too much man-made, too much bonsai and too little tree, too little soul, more form than soul, too traditional. Anyway I decided recently to drastically change the style: rotate the tree one hour clockwise, tilt it 10° to the left, cut out a few branches so one can see the interesting trunk and deadwood, cut some long branches on the right, bring down the right main branch and make a move to the left, on the left everything long, new pot. The result is clearly a different tree, a tree which does not want to be a standard bonsai, more of a tree then a bonsai, it is in the Fairy Tale Bonsai Style. The new pot is by Walter Venne form Germany. When I showed this work on the German Forum I got the remarks that the tree was great, but the pot was not liked - it looks like a ...
Walter Pall Bonsai Adventures: March 2014Walter Pall Bonsai Adventures: March 2014
Japanese yew, Taxus cuspidata, imported from Japan in 2013. I acquired the tree in may 2013 and started to redesign immediately. I somehow felt that it was a good tree, but not really great. to me it was too nice, too symmetrical, too much man-made, too much bonsai and too little tree, too little soul, more form than soul, too traditional. Anyway I decided recently to drastically change the style: rotate the tree one hour clockwise, tilt it 10° to the left, cut out a few branches so one can see the interesting trunk and deadwood, cut some long branches on the right, bring down the right main branch and make a move to the left, on the left everything long, new pot. The result is clearly a different tree, a tree which does not want to be a standard bonsai, more of a tree then a bonsai, it is in the Fairy Tale Bonsai Style. The new pot is by Walter Venne form Germany. When I showed this work on the German Forum I got the remarks that the tree was great, but the pot was not liked - it looks like a ...
Taxus o nolvadexTaxus o nolvadex
Nolvadex - Taxus pertenece al grupo de hormonas sexuales y es lo que se considerar cuidadosamente si ellos deben o no tomar Nolvadex. (continua) (continua) Código mundial antidoping: Lista de 2006* m X o Azenildo Nolvadex Tamoxusta Nolvadex Taxus Nolvadex Teatrois Triacana Teenofen.. (Taxus) Tamoxifen. buy Taxus, 30 Tabs. (Taxus) Tamoxifen in mexico online. Does cymbalta cause nasal congestion image to enlarge. Spanish Name. Price: $15.00. 1 Piece Cost. $0.00. Is 20mg of nolvadex enough for pct. taxus 30 tabs tamoxifeno 20 mg. efectos secundarios de tamoxifeno 20 mg nolvadex eod. nolvadex- o tamoxifeno 20 mg. Taxus - Novaldex - (tamoxifeno citrato) - La tienda de anabólicos. Cre dosage Venezuela o 0 1 creme tamoxifen induced hypercalcemia can get fluorescence.. Indicated for the treatment of metastatic breast cancer in postmenopausal women, tumors with estrogen receptor positive or unknown are likely to benefit most. Porque mucha gente prefiere el Nolvadex sobre el Clomid, lo que de los ...
Common Yew | About-garden.comCommon Yew | About-garden.com
Plant: Common Yew * Taxus baccata Pendula Graciosa * Syn: Taxus baccata pendula graciosa, Taxus baccata pendula overeynderi - conifer, weeping form, acicular
Taxus Cardium | Investor Relations | News ReleaseTaxus Cardium | Investor Relations | News Release
SAN DIEGO, March 17, 2014 /PRNewswire/ -- Cardium Therapeutics Inc. (Trading Symbol: CRXM) reported that it has changed its corporate name and business to Taxus Cardium Pharmaceuticals Group Inc. in connection with its strategic collaboration and funding arrangement concluded with China-based Shanxi Taxus Pharmaceuticals Co., Ltd. The strategic collaboration is designed to support the commercial development of Generx® and Excellagen® by Taxus Cardium, and also to provide new opportunities to explore the commercialization of these products for the emerging and rapidly growing advanced healthcare market in the Peoples Republic of China, and Shanxi Taxus oncology-focused product opportunities for the U.S. market. The deal includes funding in the form of direct investments in Taxus Cardium of up to $5.0 million to support the commercialization of the companys products. Stock acquired by Shanxi Taxus in connection with the strategic alliance will be purchased at a premium above the ...
Taxus chinensis - Useful Tropical PlantsTaxus chinensis - Useful Tropical Plants
Taxus chinensis has undergone a large population reduction (more than 50%) since the 1990s as a result of the discovery of the importance of this species for treating cancer. There are attempts now to propagate this species to meet the demand, however, exploitation of wild plants is likely to continue but probably at a lower rate than before. Exploitation has reduced the population in many areas of China although the species is still wide-spread. Logging and deforestation in Viet Nam may have had a bigger impact as populations there are small; it may have reduced the species to some extent to the less accessible places. The plant is classified as Endangered in the IUCN Red List of Threatened Species(2013 ...
Difference between revisions of Roberts:Publications - OpenWetWareDifference between revisions of "Roberts:Publications" - OpenWetWare
Agrawal, S.K., Chin, K.S., Sanabria-Delong, N., Aamer, K.A., Sardinha, H., Tew, G.N., Roberts, S.C. and Bhatia, S.R. (2005) Rheology and biocompatibility of poly (lactide)-poly (ethylene oxide)-poly (lactide) hydrogels. Bhatia, S.R., Khattak, S.F. and Roberts, S.C. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51. Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed Naill, M.C. and Roberts, S.C. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed Naill, M.C. and Roberts, S.C. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed Naill, M.C. and Roberts, S.C. (2005) Flow cytometric analysis ...
Difference between revisions of Roberts:Publications - OpenWetWareDifference between revisions of "Roberts:Publications" - OpenWetWare
Agrawal, S.K., Chin, K.S., Sanabria-Delong, N., Aamer, K.A., Sardinha, H., Tew, G.N., Roberts, S.C. and Bhatia, S.R. (2005) Rheology and biocompatibility of poly (lactide)-poly (ethylene oxide)-poly (lactide) hydrogels. Bhatia, S.R., Khattak, S.F. and Roberts, S.C. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51. Khattak, S.F., Bhatia, S.R. and Roberts, S.C. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed Naill, M.C. and Roberts, S.C. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed Naill, M.C. and Roberts, S.C. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed Naill, M.C. and Roberts, S.C. (2005) Flow cytometric analysis ...
UMass Amherst: Biology Department: News: Walker Named Gilgut ProfessorUMass Amherst: Biology Department: News: Walker Named Gilgut Professor
Elsbeth Walkers main area of research focuses on understanding the fundamental mechanisms underlying iron homeostasis in plants, which can set the foundation for increasing available iron in food crops. Her work on this subject began with the identification of Yellow Stripe1 (YS1), which encodes the iron-phytosiderophore transporter that is responsible for primary iron uptake in grass species. Subsequently, her group investigated the related family of proteins, YELLOW STRIPE1-LIKEs (YSLs), and demonstrated their involvement in the long distance movement of metals in plants. She is keenly interested in uncovering additional features of both the iron uptake, and long distance iron movement pathways. Elsbeth has more recently begun to investigate the genetic basis of taxol biosynthesis using cultured Taxus cells, using transcriptome analyses. She hopes that this effort will enable cheaper and more efficient production of this important anti-cancer drug.. Elsbeth is an enthusiastic teacher, and ...
Taxus baccata ( Fisheri English Yew ) | Backyard GardenerTaxus baccata ( Fisheri English Yew ) | Backyard Gardener
This cultivar is erect and has yellow to green foliage. The needles are flat and shiny. The bark is typically reddish brown and the berries, when present, are red. Branching is both horizontal and ascending. This plant likes a moist, slightly acidic soil with a decent amount of light. Excellent for
Taxus - WikipèdiaTaxus - Wikipèdia
En 1971, los quimistas Wani, Wall e Taylor isolan una molecula, lo paclitaxel o Taxòl. La rusca de Taxus brevifolia (tueis del Pacific) - que se trapa en America del Nòrd a lescai de « mètge de las selvas » - foguèt utilizada per las seunas proprietats anticancerosas. I a dins los brots joves dels taxanes (moleculas toxicas) que contenon de substàncias anticancerosas. Sol inconvenient: es rare. 10 kg de rusca de tueis del Pacific donan sonque 1 grama de produch actiu[1]. Saven que levar la rusca daqueles arbres los tua. Mai tard se produguèt per emisintèsa, amb la DAB-III una molecula presenta dins las agulhas de Taxus baccata, le taxotèr, una substéncia vesina del taxòl, mas dos còps mai eficaç. Aquela molecula es al vam de la luta anticàncer, fòrça eficaç contra los càncers del sen, de lovari, del palmon. ...
Taxus Cardium Pharmaceuticals Group, Inc. formerly Cardium Therapeutics, Inc., Mergers and Acquisitions M & ATaxus Cardium Pharmaceuticals Group, Inc. formerly Cardium Therapeutics, Inc., Mergers and Acquisitions M & A
MarketLines Company Mergers & Acquisitions (M&A), Partnerships & Alliances and Investments reports offer a comprehensive breakdown of the organic and inorganic growth activity undertaken by an organization to sustain its competitive advantage.. MarketLines Taxus Cardium Pharmaceuticals Group, Inc. (formerly Cardium Therapeutics, Inc.) Mergers & Acquisitions (M&A), Partnerships & Alliances and Investments report includes business description, detailed reports on mergers and acquisitions (M&A), divestments, capital raisings, venture capital investments, ownership and partnership transactions undertaken by Taxus Cardium Pharmaceuticals Group, Inc. (formerly Cardium Therapeutics, Inc.) since January 2007.. Key Findings. Provides intelligence on Taxus Cardium Pharmaceuticals Group, Inc. (formerly Cardium Therapeutics, Inc.)s M&A, strategic partnerships and alliances, capital raising and private equity transactions.. Detailed reports of various financial transactions undertaken by Taxus Cardium ...
NameThatPlant.net: Poa cuspidataNameThatPlant.net: Poa cuspidata
Poa cuspidata, early bluegrass. NameThatPlant.net currently features 3745 plants and 23,049 images. For many plants, the website displays maps showing physiographic provinces within the Carolinas and Georgia where the plant has been documented.
سنتز نانوذرات نقره کلوئیدی پایدار با خاصیت ضدباکتریایی با استفاده از عصارۀ گیاه سرخدار (Taxus baccata L.)سنتز نانوذرات نقره کلوئیدی پایدار با خاصیت ضدباکتریایی با استفاده از عصارۀ گیاه سرخدار (Taxus baccata L.)
مقدمه: مقاومت باکتریایی به آنتی‌بیوتیک‌ها، اهمیت توسعۀ عوامل ضدباکتریایی جدید را افزایش داده است. نانوذرات نقره می‌توانند به‌عنوان یکی از عوامل ضدباکتریایی مهم مطرح باشند. با توجه به نگرانی‌های زیست‌محیطی دربارۀ گسترش کاربرد نانوذرات نقره، استفاده از روش‌های سبز برای سنتز این نانوذرات، ضمن کاهش نگرانی‌ها می‌تواند به تکامل نانوذراتی با خصوصیات برتر نیز منجر شود. مواد و روش‌ها: عصارۀ اتانلی برگ گیاه سرخدار تهیه شد و در غلظت‌های مختلف برای احیای نیترات نقره و سنتز نانوذرات نقره استفاده شد. نانوذرات حاصل با روش‌های مختلف شامل طیف‌سنجی مرئی- ماوراء
Antisense-induced suppression of taxoid 14β-hydroxylase gene expressio by Feng-Lan Li, Xiao-Jun Ma et al."Antisense-induced suppression of taxoid 14β-hydroxylase gene expressio" by Feng-Lan Li, Xiao-Jun Ma et al.
The enzyme taxoid 14β-hydroxylase (14OH) directs a side-route of taxol pathway to 14β-hydroxy taxoids. Suppression of this side-route could increase the production of taxol. To suppress taxoid 14β- hydroxylase gene (14OH) expression in theTaxus × media TM3 cell line, antisense RNA inhibition approach was used in this study. Following the construction of an antisense RNA expression vector of 14OH from Taxus chinensis, the antisense 14OH cDNA (as14OH) was introduced into TM3 cells by Agrobacterium tumefaciens-mediated transformation. Southern blot analysis of hygromycin phosphotransferase gene (HYG) revealed that this selection gene was integrated successfully into the genome of Taxus × media cells. Reverse transcription-polymerase chain reaction (RT-PCR) analysis showed that the 14OH mRNA level in transgenic cells dropped dramatically, suggesting that the expression of endogenous14OH gene was significantly suppressed by the exogenous as14OH gene. Correspondingly, the total yield of three major C-14
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EPO - T 1219/03 (Production of taxol/PHYTON INC.) of 25.8.2005EPO - T 1219/03 (Production of taxol/PHYTON INC.) of 25.8.2005
Summary of Facts and Submissions. I. European Patent No. 0 672 162 (application No. 93 906 156.0) was filed on 22 February 1993. The patent relates to the enhanced production of taxol and taxanes by cell cultures of Taxus species and was granted on the basis of 9 claims, of which claims 1 and 9 read as follows:. 1. A process for recovering taxol and other taxanes in high yields from cell cultures of a Taxus species comprising: cultivating in suspension culture, in one or more nutrient media under growth and product formation conditions, cells of a Taxus species derived from callus and/or suspension cultures and recovering said taxol and other taxanes from said cells and/or said medium of said cell culture, said conditions comprising one or more of: continuous or intermittent illumination with broadband or narrowband light; or nutrient media which are of altered medium composition for growth and production phases of the culture.. 9. A process as claimed in anyone of claims 1 to 8, wherein ...
Fungi Associated with Root Rot of Pinus wallichiana Seedlings in KashmirFungi Associated with Root Rot of Pinus wallichiana Seedlings in Kashmir
Abstract: This study was conducted to find out the cause of root rot disease of blue pine (Pinus wallichiana) seedlings which is an important limiting factor in its successful production right from the nursery raising. The pathogens associated with the disease were isolated, morphologically characterised and identified as Fusarium oxysporum f.sp. pini (Schlecht.) Synd. and Hans., Rhizoctonia solani Kuhn and Macrophomina phaseolina (Tassi) Goid. F. oxysporum was the most abundant pathogenic fungus in diseased roots of blue pine seedlings with isolation frequency of 38.6%, whereas R. solani and M. phaseolina showed isolation frequencies of 11.0 and 3.3%, respectively. All the three fungi proved pathogenic and caused characteristic root rot symptoms when inoculated separately. Root rot disease of Pinus wallichiana seedlings was prevalent in all the three districts of Kashmir valley surveyed, during 2008 and 2009. ...
Tahki Coast Yarn - 20 Yew Berry at Jimmy Beans WoolTahki Coast Yarn - 20 Yew Berry at Jimmy Beans Wool
Tahki Coast Yarn - 20 Yew Berry - This all-season wool-cotton blend is perfect for sea-worthy knits, such as cables and Fair Isles. The worsted weight yarn is overdyed for a heathery effect in a palette of misty shades. Tahki Coast Yarn - 20 Yew Berry is available now at Jimmy Beans Wool with Free U.S. Flat Rate shipping for orders over $75, $4 U.S. Flat Rate shipping on all other orders!
Anticonvulsant, analgesic and antipyretic activities of Taxus wallichi by Muhammad Nisar, Inamullah Khan et al."Anticonvulsant, analgesic and antipyretic activities of Taxus wallichi" by Muhammad Nisar, Inamullah Khan et al.
Taxus wallichiana Zucc. (Himalayan Yew) is often used in northern areas of Pakistan for the treatment of pyrexia, acute pains and epilepsy. We have investigated certain pharmacological activities of the methanol leaf extract against convulsion, nociception and pyrexia induced in rodents. The aim was to justify and explore its folk uses in these pathological conditions, on scientific basis. The studies were carried out using acetic acid-induced nociception and pentylenetetrazole-induced convulsions in mice, while formalin test and yeast-induced pyrexia in rats. Significant analgesic (67.77 and 74.29%) effect was found in acetic acid-induced model at doses of 100 and 200 mg/kg, i.p. respectively. Crude extract exhibited significant (P | 0.05) inhibition of the formalin noxious stimulation on both early and late phases of pain by the extracts (100 and 200 mg/kg doses). In case of yeast-induced pyrexia model, 200 mg/kg dose showed very significant (P | 0.01) inhibition while 50 and 100 mg/kg dose caused a
Boston Scientific: Taxus stent sales were off 25 percent during Q2 - MassDeviceBoston Scientific: Taxus stent sales were off 25 percent during Q2 - MassDevice
Sales of Boston Scientific Corp.s Taxus drug-eluting stent line fell 25 percent during the three months ended June 30, according to a detailed earnings report filed with the Securities and Exchange Commission. Total second-quarter sales for the coronary stent system were $269 million, compared to $358 million during the same period last year. Thats a slight improvement from the first quarter, which saw Taxus sales slide 28 percent compared with the first quarter of 2008.. The modest rebound jibes with a report by Angiotech, the Vancouver-based pharmaceutical company that makes the drug used in the stents coating. Angiotech said the royalties it derives from Taxus sales were showing small signs of improvement after several down quarters. But the details suggest the rebound for BSCs overall drug eluting stent business wasnt as robust as initially reported. In July, BoSci said second-quarter drug-eluting stent sales increased by $63 million in the U.S., or 36 percent. Included in that ...
Yew - Everything2.comYew - Everything2.com
European yew - Taxus baccata - also known as the common yew One of the 3 native evergreens of Great Britain, the yew is a type of conifer, although it b...
Scinax cuspidatus (Lutz, 1925) | Amphibian Species of the WorldScinax cuspidatus (Lutz, 1925) | Amphibian Species of the World
Hyla cuspidata Lutz, 1925, C. R. Mém. Hebd. Séances Soc. Biol. Filial., Paris, 93 (1925, vol. 2): 211. Syntypes: Not stated, by museum records AL-MNRJ 299-302, UMMZ 64149 (according to Peters, 1952, Occas. Pap. Mus. Zool. Univ. Michigan, 539: 16), and MCZ 12889 (according to Barbour and Loveridge, 1929, Bull. Mus. Comp. Zool., 69: 278) and (according to Cochran, 1961, Bull. U.S. Natl. Mus., 220: 53) USNM 96139, 96147-49, 96370. Type locality: Rio-de-Janeiro, Brazil. Syntypes from Manguinhos, Rio de Janeiro, Brazil and Rio de Janeiro, Brazil according to Cochran, 1961, Bull. U.S. Natl. Mus., 220: 53.. Ololygon cuspidata - Fouquette and Delahoussaye, 1977, J. Herpetol., 11: 387-396.. Scinax cuspidata - Duellman and Wiens, 1992, Occas. Pap. Mus. Nat. Hist. Univ. Kansas, 151: 16, 21.. Scinax cuspidatus - Köhler and Böhme, 1996, Rev. Fr. Aquar. Herpetol., 23: 139.. ...
Clinical Outcome of Patients With and Without Diabetes Mellitus After Percutaneous Coronary Intervention With the Resolute...Clinical Outcome of Patients With and Without Diabetes Mellitus After Percutaneous Coronary Intervention With the Resolute...
In general, randomized trials are more rigorous than observational studies, yet they are often limited in power to address many individual clinical questions, due to the sample size of individual populations. Therefore, an acceptable compromise of a prospectively planned analysis compared with a performance goal was derived from historical data. This acceptability of a performance goal study on the basis of historical data was used for U.S. approval of the first-generation Taxus Liberté PES (Boston Scientific, Natick, Massachusetts) (31). The TAXUS ATLAS trial (TAXUS ATLAS: A Multi-center, Single-arm Study of the TAXUS Liberté-SR Stent for the Treatment of Patients With de Novo Coronary Artery Lesions)-a prospective, single-arm study in de novo coronary lesions-compared treatment with the Taxus Liberté PES versus a matched historical control group of patients from the TAXUS-IV and -V trials treated with the Taxus Express PES (31). The Taxus Liberté PES met its performance goal as compared ...
Serval - Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew...Serval - Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew...
The toxicity of yew (Taxus spp) is well known from ancient times and is mainly due to taxins acting as inhibitors of calcium and sodium transport across the cell membrane of cardiac myocytes. The confirmation of yew taxins in body fluids can be carried out by liquid chromatography-tandem mass spectrometry (LC-MS/MS). However, before selecting this precise but expensive technique, an orientation test should be done to ascertain yew presence as toxic agent in the organism. As the 3,5-dimethoxyphenol (3,5-DMP), myrtenol and 1-octen-3-ol appear as glycosidically bound volatile compounds and are very yew specific, the detection of 3,5-DMP and the measurement of 1-octen-3-ol / myrtenol concentration ratio constitute reliable indicators of yew presence in forensic cases. The detection of these compounds is easily performed by gas chromatography-mass spectrometry (GC-MS) (SIM) after an enzymatic hydrolysis (β-glucosidase) allowing the release of volatile compounds from yew glycosides. Copyrigh
New Study Suggests Better Patient Outcomes with CYPHER,Sirolimus-Eluting Coronary Stent than with Taxus Stent in,Real-World...New Study Suggests Better Patient Outcomes with CYPHER,Sirolimus-Eluting Coronary Stent than with Taxus Stent in,Real-World...
Registry Analysis Published in Journal Heart Finds Taxus StentImplan... ...MIAMI LAKES Fla. June 4 2007 /PRNewswire via COMTEX NewsNetwork/ -...The authors of the analysis sought to identify risk factors forsympto... The major new finding of this study was that the use of theTaxus Ste...,New,Study,Suggests,Better,Patient,Outcomes,with,CYPHER,Sirolimus-Eluting,Coronary,Stent,than,with,Taxus,Stent,in,Real-World,Clinical,Settings,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
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SID-530 | CAS# | microtubule inhibitor | MedKoo BiosciencesSID-530 | CAS# | microtubule inhibitor | MedKoo Biosciences
SID-530 is an intravenous formulation containing docetaxel, a semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata, with potential antineoplastic activity. Taxol analogue SID 530 binds to and stabilizes tubulin, inhibiting microtubule disassembly, which results in cell-cycle arrest at the G2/M phase and cell death. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) (last updated: 6/23/2015)
docetaxel | Semantic Scholardocetaxel | Semantic Scholar
A semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and cell death. This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Docetaxel has been studied for use as a radiation-sensitizing agent. (NCI04)
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California yew synonyms | Best 3 synonyms for California yewCalifornia yew synonyms | Best 3 synonyms for California yew
The best 3 synonyms for California yew, including: pacific yew, western yew, Taxus brevifolia and more... Find another word for California yew at YourDictionary.
Tropicos | Name - !Calliergonella cuspidata (Hedw.) LoeskeTropicos | Name - !Calliergonella cuspidata (Hedw.) Loeske
Plantas medianas a algo robustas, formando manojos laxos a densos, verde brillantes a amarillas o pardo-doradas. Tallos erectos o ascendentes, poco a muy ramificados, ramas cortas, generalmente cuspidadas en los extremos; hialodermis presente en sección transversal, cordón central débil; párafilos ausentes; pseudoparáfilos foliosos. Hojas subjuláceas, erectas, anchamente ovadas a ovado-oblongas, aprox. 2-2.5 mm de largo hasta 2 mm de ancho, profundamente cóncava, ápice obtuso a agudo-redondeado, base auriculada; márgenes planos abajo, incurvos arriba, enteros; costa ausente u ocasionalmente corta y doble (raramente hasta 5-furcada); células apicales cortas, 10-25 µm de largo, 4-5 µm de ancho; células mediales lineares, 50-90 µm de largo, 2-4 µm de ancho; región alar ± excavada, células ovales a oblongas, 50-100 µm de largo, 25-50 µm de ancho, hileras externas hialinas, de paredes delgadas, hileras internas dorado-amarillas; células de la inserción alargadas, fuertemente ...
UTEX LB FD262 Craticula cuspidata | UTEX Culture Collection of AlgaeUTEX LB FD262 Craticula cuspidata | UTEX Culture Collection of Algae
Algae Detail UTEX Number: FD262Class: BacillariophyceaeStrain: Craticula cuspidataMedia: CHEV Diatom MediumOrigin: Arizona, USADescription of Location: Type Cul
Tropicos | Name - !Calliergonella cuspidata (Hedw.) LoeskeTropicos | Name - !Calliergonella cuspidata (Hedw.) Loeske
Chinese specimens examined: Heilongjiang: Dailing, Kozlov 29 (MO); Ning-an Co., C. Gao 3465, G.-Y. Li 10326 (both in IFSBH); Xiao Xing An Ling (Mt.), T. Cao 40217 (MO); Yichun City, C. Gao 124, Y.-H. Wu 1388 (both in IFSBH). Henan: Tong-bai Co., L.-S. Gong 171 (MO). Jilin: An-tu Co., K.-C. Lang 58 (MO, PE), Koponen 36943 (PE); Dun-hua Co., K.-Q. Zhou 292 (PE); Hua-dian Co., K.-Y. Zhao 17 (IFSBH); Hui-nan Co., K.-Y. Zhao 24 (IFSBH); Jiao-he Co., C. Gao 1495, 1550 (both in IFSBH, MO); Jing-yu Co., K.-Y. Zhao 63 (IFSBH); Jiu-tai Co., C. Gao 1796, 1797 (both in IFSBH, MO); Lin-jiang Co., S.-E. Liu 8889 (MO); Mt. Changbai, Vitt 34807 (ALTA, MO); Pan-shi Co., K.-Y. Zhao 5, 14 (both in IFSBH); Tong-hua Co., K.-Y. Zhao 47 (IFSBH); Yong-ji Co., K.-Y. Zhao 20, 21 (both in IFSBH). Liaoning: Kuan-dian Co., Y.-H. Wu 1178 (IFSBH); Xin-bin Co., C. Gao & E.-Z. Bai 40509 (IFSBH, MO). Nei Mongol: Da Xing An Ling (Mt.), X.-L. Bai 530 (NY); Gen-he, C. Gao 732, 3515 (both in IFSBH). Shaanxi: Tai-bai Co., X.-J. Li ...
UC/JEPS: Jepson Manual treatment for DOWNINGIA cuspidataUC/JEPS: Jepson Manual treatment for DOWNINGIA cuspidata
Flower sessile, generally inverted at full bloom by twisted ovary; corolla generally ,, calyx, blue to pink or white, generally with a symmetric white or yellow spot on lower lip, tube entire, limb strongly 2-lipped, generally 2 lobes of upper lip , 3 of lower; stamens fused (filaments, anthers in tubes), generally 2 smaller anthers each with terminal tuft of bristles, 1 triangular or horn-like, generally 0.2 0.5 mm, others linear, shorter; ovary pedicel-like, chambers 1 2, placentas parietal or ...
Publications - joanne yew laboratoryPublications - joanne yew laboratory
Shankar S, Calvert MEK, and Yew JY. 2015. Measuring physiological responses of Drosophila sensory neurons to lipid pheromones using live calcium imaging. J Vis Exp. In press. Ng WC, Chin JSR, Tan KJ, Yew JY. 2015. The fatty acid elongase Bond is essential for Drosophila sex pheromone synthesis and male fertility. Nat Commun. 6:9263. Reiff T, Jacobson J, Cognigni P, Antonello Z, Ballesta E, Tan KJ, Yew JY, Dominguez M, Miguel-Aliaga I. 2015. Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. Elife. 4:e06930 Shankar S, Chua JY, Tan KJ, Calvert ME, Weng R, Ng WC, Mori K, Yew JY. 2015. The neuropeptide tachykinin is essential for pheromone detection in a gustatory neural circuit. Elife. 4:e06914. Yew JY and Chung H. 2015. Insect pheromones: an overview of function, form, and discovery. Prog Lipid Res. 59: 88-105. Vasudevan A, Kumar V, Chiang YN, Yew JY, Cheemadan S, and Vyas A. 2015. Aplha2u-glubulins mediate manipulation of host
Taxus floridana (Florida Yew)Taxus floridana (Florida Yew)
Clear felling of Pinus palustris forests during the 19th century along with selective logging of the slope forests in the early 1900s may have resulted in range reduction and habitat fragmentation during the 19th and 20th centuries (Reinsmith and Foreman 1934, Kwit 1998). The most immediate threat facing Florida yew is the lack of regeneration; a causal agent for this has not yet been identified. Rubbing and browsing by white tailed deer is also a problem as it may lead to the death of individual stems. As hunting within protected areas is prohibited, deer numbers within these areas increase during the hunting season (winter), resulting in increased pressure on the yew trees ...
Takahashi Taxol total synthesis - WikipediaTakahashi Taxol total synthesis - Wikipedia
The Takahashi Taxol total synthesis published by Takashi Takahashi in 2006 is one of several successful methods in taxol total synthesis. The method starts from geraniol and differs from the other 6 published methods that it is a formal synthesis (the final product is baccatin III which lacks the amide tail found in taxol itself) and that it is racemic (the product baccatin III is optically inactive). A key feature of the published procedure is that several synthetic steps (construction of rings A, B and C) were performed in an automated synthesizer on a scale up to 300 gram and that purification steps were also automated. Ring A was synthesised starting from geraniol 1 and involved acylation (acetic anhydride, DMAP, Et3N) to 2, epoxidation (N-bromosuccinimide, tBuOH/H2O then triethylamine) to 3, radical cyclisation (titanocene dichloride, manganese, triethylborane, 2,6-lutidine) to 4, alcohol protection (ethyl vinyl ether, camphorsulfonic acid) to 5, alcohol deprotection (NaOH, MeOH/THF/H2O) to ...
CHINESE HERB PAIRED WITH IRON KILLS 98 PERCENT OF BREAST CANCER CELLS IN 16 HOURS!CHINESE HERB PAIRED WITH IRON KILLS 98 PERCENT OF BREAST CANCER CELLS IN 16 HOURS!
Some herbal remedies are showing great results when research is applied. Even the potent anticancer drug taxol comes from the bark of the yew tree. Many people are hesitant to take herbs due to the fact that they are not regulated by the Food and Drug Administration. For people who are interested in using herbs, seek out the care of a specialist who can help guide you and assure that any herbs you are taking are being dosed properly and will not have a negative interaction with any medications that you may currently be taking. For many taking herbs may seem like an attractive option but many wonder what herbs are best ...
Chiral Enzymatic Activity in Cell Cultures of Taxus SpeciesChiral Enzymatic Activity in Cell Cultures of Taxus Species
The results showed an oscillatory behavior between er and reaction time, resulting in enantioselectivity changes according to pH conditions within 1 week. In the course of 1 day, we observed an increase of er in all pH treatments, but by the second day the opposite was observed with the exception of the treatment at pH 6.5 and 8.0. By the third day, a decrease in er was observed at pH 6.5, whereas a continuous increase was observed at pH 8.0. These results exhibited no periodic dependence between er and reaction time. Both enantiomers were identified as the main product in the enantiomeric mixture. At pH values of 4.0 and 6.0, the oscillatory behavior was also present, but the opposite enantioselectivity was observed during the reaction course because the (R)-enantiomer was mainly obtained. Enantioselective changes were previously reported when racemic benzoin was deracemized by Rhizopus oryzae at pH 7.5-8.0 and pH 4.0-5.0 [29].. The present results suggest that Taxus globosa Schltdl. cells are ...
Drug-eluting stent thrombosis in routine clinical practice two-year outcomes and predictors from the Taxus arrive registries<...Drug-eluting stent thrombosis in routine clinical practice two-year outcomes and predictors from the Taxus arrive registries<...
TY - JOUR. T1 - Drug-eluting stent thrombosis in routine clinical practice two-year outcomes and predictors from the Taxus arrive registries. AU - Lasala, John M.. AU - Cox, David A.. AU - Dobies, David. AU - Baran, Kenneth. AU - Bachinsky, William B.. AU - Rogers, Edwin W.. AU - Breall, Jeffrey A.. AU - Lewis, David H.. AU - Song, Aijun. AU - Starzyk, Ruth M.. AU - Mascioli, Stephen R.. AU - Dawkins, Keith D.. AU - Baim, Donald S.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 2009/8. Y1 - 2009/8. N2 - Background-Stent thrombosis (ST) is an uncommon but serious complication of drug-eluting and bare metal stents. To assess drug-eluting stent ST in contemporary practice, we analyzed 2-year data from the 7492-patient ARRIVE registry. Methods and Results-Patients were enrolled at the initiation of percutaneous coronary intervention with no inclusion/ exclusion criteria beyond use of the paclitaxel-eluting TAXUS stent. Two-year follow-up was 94% with independent ...
SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries - Tabular...SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries - Tabular...
Due to the introduction of drug-eluting stents (DESs) and to improvements in therapy for both percutaneous coronary intervention (PCI) and coronary artery bypass surgery (CABG) patients, PCI is challenging CABG as the gold standard for treatment of three vessel (3VD) and left main (LM) coronary disease.. SYNTAX is a novel, randomized trial with nested registries comparing PCI with paclitaxel-eluting TAXUS stents to CABG for 3VD and LM patients to evaluate the best treatment for these patients with complex coronary disease.. Patients at participating centers will be evaluated by both a cardiothoracic surgeon and by an interventional cardiologist.. Those patients who are determined to be eligible for treatment by both PCI and CABG will be randomized to receive either PCI with a polymer-based paclitaxel-eluting TAXUS stent or CABG.. Patients who are determined to be unsuitable for treatment by PCI will be treated by CABG and will be entered into a CABG registry to help define the patient population ...
Optimize Suspension Cell Culture with Corning Mini Bioreactors | SelectScienceOptimize Suspension Cell Culture with Corning Mini Bioreactors | SelectScience
The new Corning Mini Bioreactors are ideal for high throughput process optimization for suspension cell culture. Consisting of a 50mL centrifuge polyprene tube with a vented cap, Corning Mini Bioreactors are sterile, nonpyrogenic, RNase-/DNase-free and are suitable for cell line development, clone selection, media optimization and recombinant protein development.
Vol 7: Development and application of an automated, multiwell plate based screening system for suspension cell culture. - pdf...Vol 7: Development and application of an automated, multiwell plate based screening system for suspension cell culture. - pdf...
Vol 7: Development and application of an automated, multiwell plate based screening system for suspension cell culture.. This article is from BMC Proceedings, volume 7.AbstractNone . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Common yew | definition of Common yew by Medical dictionaryCommon yew | definition of Common yew by Medical dictionary
Looking for online definition of Common yew in the Medical Dictionary? Common yew explanation free. What is Common yew? Meaning of Common yew medical term. What does Common yew mean?
At Least We Know These Dont Work: Negative Trials at CTAD | ALZFORUMAt Least We Know These Don't Work: Negative Trials at CTAD | ALZFORUM
Adam Boxer, University of California, San Francisco, presented his centers Phase 1 trial of TP1 287. Also known as abeotaxane, this small-molecule taxol derivative stabilizes microtubules. TPI 287 accumulates in the brain, and has been tested primarily to treat central nervous system tumors. Its application to tauopathies grew out of work showing beneficial effects of the microtubule stabilizer epothilone D in tau transgenic mice (Zhang et al., 2012). Testing of epothilone D in AD patients started in 2012 but was discontinued for lack of efficacy.. Boxers group examined the safety and tolerability of TP1 287 in 44 people with the primary four-repeat tauopathies cortical basal degeneration (CBD) or progressive supranuclear palsy (PSP), and in 33 people with AD. Participants received abeotaxane by intravenous infusion once every three weeks for nine weeks, with an option for open-label extension up to three months.. In recruiting for the CBD cohort, Boxer screened with amyloid PET to exclude ...
Paclitaxel ManufacturerPaclitaxel Manufacturer
Today, Biolyse Pharma is the industry leader in the research and development of injectable Paclitaxel products for use in cancer treatments.. Since Biolyse researchers first discovered that Paclitaxel could be produced from Taxus canadensis the company has gained fourteen years of valuable experience with the product. In September of 1994, Biolyse obtained authorization from the Federal Health Protection Branch (HPB) to administer its Paclitaxel for Injection, to patients under a clinical trial program.. Paclitaxel is a chemotherapeutic agent that is currently prescribed worldwide to treat the most aggressive forms of ovarian, lung and breast cancer, as well as AIDS related Kaposis sarcoma. Paclitaxel belongs to the chemical group known as taxanes, a family of molecules found in various natural sources. Paclitaxel is considered by the scientific and medical community as a first line of defense in the treatment of cancer. In 1992, both the American and Canadian National Cancer Institutes ...
Goodbye, Toxic Taxus: Yew Plants Are Killing Wildlife - Hobby FarmsGoodbye, Toxic Taxus: Yew Plants Are Killing Wildlife - Hobby Farms
The yew, popular in residential landscaping, is used to discourage wild animals from grazing, but in the U.S. it has killed elk, moose and bears.
Scientific Protocols - Immortalization of adult human colonic epithelial cells extracted from normal tissues obtained via...Scientific Protocols - Immortalization of adult human colonic epithelial cells extracted from normal tissues obtained via...
Reagent Set-up:. Solution A To make one liter: Add to 700 ml of DI water 71.48 gm of Hepes, 10 ml of Phenol Red (1.75mg/ml), Sodium Hydroxide to bring to pH of 7.0, 7.2 gm of glucose, 2.24 gm of potassium chloride, 71.28 gm of sodium chloride, and 1.42 gm of sodium phosphate. pH again to 7.5 then add 300 ml of DI water to complete volume to 1 liter. Sterile filter (22 micron filter) and keep in 4C.. Digestion enzyme stocks Make 10x stocks of collagenase type 1 and 100x stocks of dispase. For collagenase type 1, add 13,659 U to 9.1 ml of X media (final concentration= 1500U/ml). For dispase, add 5mg to 1.25 ml of X media (final concentration= 4mg/ml). Stocks can be stored for up to 2 weeks in -20C.. 1x digestion mix Combine together 3.0 ml of 10x collagenase, 300 μl of 100x dispase, 750 μl of fetal bovine serum, and approximately 26 ml of X media to make 30 mls of digestion mix. Final concentrations of enzymes in 1x digestion mix: collagenase= 150 U/ml, dispase= 40 μg/ml; final percentage of ...
Why do cats eat plants, and should I be worried? | Dr. Justine Lee, DVM, DACVECC, DABT, Board-Certified Veterinary Specailist -...Why do cats eat plants, and should I be worried? | Dr. Justine Lee, DVM, DACVECC, DABT, Board-Certified Veterinary Specailist -...
Other dangerous types of plants? Cardiac glycosides like foxglove, lily of the valley, kalanchoe, Japanese yew, etc. Most of these grow outside, but when in doubt, Id keep these out of reach. This type does not cause kidney failure, but can cause life-threatening heart arrhythmias and death when ingested by dogs or cats.. Another common houseplant that cats seen to chew on are Dieffenbachia or philodendron. These plants contain insoluble calcium oxalate (not soluble calcium oxalate, like so many websites erroneously mention!), which cause oral pain when chewed on. This isnt life-threatening however, and typically just results in foaming and frothing at the mouth. My advice? Keep these plants elevated out of reach, and if your cat does get into it, just offer something tasty to flush out the mouth - a small amount of chicken broth, canned tuna water (not oil!), or even chicken noodle soup. If your cat continues to vomit, a veterinary visit is a must.. My hint? I keep one spider plant in my ...
Most recent papers with the keyword Developement | Read by QxMDMost recent papers with the keyword Developement | Read by QxMD
Numerous studies have documented the negative effects of ozone (O3) on tree species in growing season, however, little is done in non-growing season. Three evergreen tree species, Phoebe bournei (Hemsl.) Yang (P. bournei), Machilus pauhoi Kanehira (M. pauhoi) and Taxus chinensis (Pilger) Rehd (T. chinensis), were exposed to non-filtered air, 100 nmol mol-1 O3 air (E1) and 150 nmol mol-1 O3 air (E2) in open-top chambers in subtropical China. In the entire period of experiment, O3 fumigation decreased net photosynthesis rate (Pn) through stomatal limitation during the transition period from growing to non-growing season (TGN), and through non-stomatal limitation during the period of non-growing season (NGS) in all species tested ...
Arsenic and Old Leaves: The Art of Poisoning Your Fantasy Characters - Part 2 « Fantasy-FactionArsenic and Old Leaves: The Art of Poisoning Your Fantasy Characters - Part 2 « Fantasy-Faction
Oooh, yummy red berries… and look, the birds are eating them! How tasty, Ill have another one… *yawn*… and maybe just lay down here for a quick nap…". …and then never wake up? Ah, yes. The allure of the English or European yew tree-lovely to look at, and tempting to take a bite from, and even better if you never want to wake up again.. In England, the yew is commonly known as "the graveyard tree", though actually for more of an historical reason than anything ominous. Roman invaders to England used to hold church services under yew trees, and thus ancient yews are still occasionally found next to churches in England-just like graveyards.. Nearly every part of the yew tree is poisonous, with one small exception: the flesh of its bright, red berries. However, inside the aril is a poisonous seed, which can easily be ingested by accident. The color and shape of the berries is highly tempting for children, animals, and hungry passers-by, but eating even just a few seeds or leaves can be ...
chy1 - Cyanide hydratase - Gibberella baccata - chy1 gene & proteinchy1 - Cyanide hydratase - Gibberella baccata - chy1 gene & protein
Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants (PubMed:8409923). Has also low but significant nitrilase activity with acetonitrile, propionitrile and benzonitrile (PubMed:12725921).
Development of an automated, multiwell plate based screening system for suspension cell culture | BMC Proceedings | Full TextDevelopment of an automated, multiwell plate based screening system for suspension cell culture | BMC Proceedings | Full Text
An automated media blend screening was carried out in a second experiment highlighting another main area of application. Two seed trains of a CHO cell line, media blends of two growth media and two feeding strategies were screened in 120 wells on 6 well plates. A success rate of 100 % enabled the evaluation of all wells in terms of cell growth and productivity. An increase in viable cell density and product titer of about 20% in comparison to the reference process was achieved.. 2 L bioreactor runs were performed to confirm these optimized parameters. A total of 6 bioreactor runs using the identified best combination of media blends, seed train and feeding strategy verified the predicted results from the multiwell plates and showed an increase in productivity of about 15 %.. ...
DMOZ - Health: Pharmacy: Drugs and Medications: P: PaclitaxelDMOZ - Health: Pharmacy: Drugs and Medications: P: Paclitaxel
Paclitaxel is a chemotherapeutic drug originally developed from the bark of the Pacific Yew tree. Given the relative scarcity of Pacific Yew trees and environmental concerns over their loss, scientists sought to synthesize the product but settled instead on semisynthesizing it from the needle of the English Yew, a procedure now used in the creation of Bristal-Myers Squibbs Taxol. Paclitaxel was approved by the FDA in 1992 for use in the treatment of ovarian cancer and in 1994 for use in the treatment of breast cancer. It is not a cure for cancer but it may stop the abnormal cancer cells from dividing and growing so they eventually die.
WIPO Panel Rules Boston Scientific Liberte(R) and TAXUS(R) Liberte(R) Stents Do Not Infringe Medinol PatentsWIPO Panel Rules Boston Scientific Liberte(R) and TAXUS(R) Liberte(R) Stents Do Not Infringe Medinol Patents
Boston Scientific Corporation (NYSE: BSX) announced today that a World Intellectual Property Organization (WIPO) arbitration panel has issued its ruling in an arbitration between
LEE KWAN YEW, Father of Modern Singapore, 1924-2015LEE KWAN YEW, Father of Modern Singapore, 1924-2015
Lee Kuan Yew, who led Singapore into prosperity over 30-year rule, dies at 91 By William Branigin March 22 Lee Kuan Yew, whose efficient but often heavy-handed leadership helped transform Singapore from a chaotic British colonial backwater into one of the worlds most prosperous and orderly states, died March 23 in a Singapore hospital. He was 91. Mr. Lee had been hospitalized with pneumonia since February. The prime ministers office announced the death. As prime minister
Money in Stents -- The Motley FoolMoney in Stents -- The Motley Fool
handily beat Wall Street estimates when it reported a 38% earnings increase. The highlight was the success of its Taxus coronary stent. Blockbuster news could be on the horizon.. A stent is a wire mesh that keeps open surgically cleared arteries. One of the limitations of bare metal stents is that 30% of patients develop scar tissue that can cause re-blockage. Boston Scientific sells a drug-coated stent in Europe that limits this scarring from occurring.. The future for stents is bright. Boston Scientific believes its 2005 stent market opportunity is 50% of a $5 billion market. When you have total sales of $876 million in the latest quarter, this potential is a rare opportunity.. The Taxus drug-coated stent achieved a number of milestones in the latest quarter. Sales were up 100%. European sales exceeded those of the only other drug-coated stent on the market -- Johnson & Johnsons ...
SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries - Study...SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries - Study...
Additive EuroSCORE is a prognostic scoring system calculating predicted operative mortality for patients undergoing cardiac surgery; it has been the most rigorously evaluated scoring system in cardiac surgery. A predetermined weighted score is assigned for specified patient-, cardiac-, and operation-related factors; for example, pulmonary hypertension is assigned a score of 2. The sum of scores is the additive EuroSCORE. EuroSCORE is calculated from site reported baseline data. A score of greater than 6 is considered as being predictive of an increased mortality risk. (www.euroscore.org ...
Plant Cell Culture: Essential MethodsPlant Cell Culture: Essential Methods
... provides the reader with a concise overview and is an essential laboratory manual for students and early-career researchers.
Cancer Drug Stimulates Tripolar Mode of Mitosis - Science and Technology Research NewsCancer Drug Stimulates Tripolar Mode of Mitosis - Science and Technology Research News
Taxane-based radiochemotherapy* is widely used in the treatment of various locally advanced cancers - including non-small-cell lung carcinoma (NSCLC). Taxanes have two effects: they inhibit cell division, and they also sensitize tumor cells for radiation therapy. Researchers at the Department of Radiation Therapy & Radiooncology at Munich University Hospital and the Radiation Cytogenetics Research Unit at Helmholtz Zentrum München have now demonstrated in detail how this works.. Specifically, the scientists investigated the effect of Paclitaxel, a member of the taxane family isolated from the bark of the Pacific yew (Taxus brevifolia). "By using cell biological and biochemical approaches, we were able to show in the present study that clinically relevant doses of Paclitaxel induce tripolar instead of normal bipolar cell division," said first author Dr. Michael Orth of Munich University Hospital. Put in simple terms, instead of dividing into two cells, the cell divides into three. "Tumor cells ...
Yew Poisoning in Cats - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, CostYew Poisoning in Cats - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
The yew is a common evergreen tree that is toxic to all animals including cats. If ingested, muscle tremors, seizures, respiratory distress, and cardiac failure resulting in death can occur. - Wag! (formerly Vetary)
Singapore PMs siblings publicly denounce himSingapore PM's siblings publicly denounce him
We believe, unfortunately, that Hsien Loong is driven by a desire for power and personal popularity. His popularity is inextricably linked to Lee Kuan Yews legacy.. His political power is drawn from his being Lee Kuan Yews son. We have observed that Hsien Loong and Ho Ching want to milk Lee Kuan Yews legacy for their own political purposes.. We also believe, based on our interactions, that they harbour political ambitions for their son, Hongyi.. They reiterated their fathers wish to demolish his house at 38, Oxley Road (photo, above) upon his passing, and accused Hsien Loong and Ho Ching of wanting to preserve the house to enhance his political capital.. "The values of Lee Kuan Yew are being eroded by his own son. Our father placed our country and his people first, not his personal popularity or private agendas.. We are very sad that we have been pushed to this. We feel hugely uncomfortable and closely monitored in our own country. We do not trust Hsien Loong as a brother or as a ...
Taxane and Taxoid Chemotherapeutic Agents - Iwao OjimaTaxane and Taxoid Chemotherapeutic Agents - Iwao Ojima
The long-term objective of this research program is to discover and develop new and effective chemotherapeutic agents for fight against cancer, including cytoto...
Doc says med manufacturers using his stent technology | SE Texas RecordDoc says med manufacturers using his stent technology | SE Texas Record
BCS Taxus coronary stent A surgeon considered a leader in cardiac stent technology is taking on Boston Scientific Corp. and Johnson & Johnson for infringement of his patents.
Boston Scientific Reports Expanded Trial of Stent Showed Positive Data - WSJBoston Scientific Reports Expanded Trial of Stent Showed Positive Data - WSJ
Boston Scientific said its Taxus Express2 stent system showed significant reduction of the recurrence of a narrowing of arteries in diabetic patients.
Regional & Local Websites | Members | Alcoholics Anonymous (Great Britain) LtdRegional & Local Websites | Members | Alcoholics Anonymous (Great Britain) Ltd
The Saturday, 7pm meeting at St Helens Church, Solihull, will be held at St Michael Angel Church, corner of Rowland Road and Yew Tree Lane, Yardley, B26 1AP, on Jan 20th, Jan 27th and Feb 3rd at 7pm. It will return back to St Helens on 10th Feb. ...
Streptopus parviflorus in Flora of China @ efloras.orgStreptopus parviflorus in Flora of China @ efloras.org
5. Streptopus parviflorus Franchet, Nouv. Arch. Mus. Hist. Nat. ser. 2, 10: 89. 1887. 小花扭柄花 xiao hua niu bing hua Streptopus mairei H. Léveillé.. Rhizome short, thickened. Stem usually branched distally, 20--50 cm, glabrous. Leaves lanceolate to ovate-lanceolate, 4--8 × 1.5--4 cm, thinly papery, base cordate, margin entire, apex acuminate. Peduncle 2.5--4 cm, glabrous, neither jointed nor geniculate, 1- or 2-flowered. Flowers nodding. Tepals white, lanceolate, 6.5--8 × 1--2 mm. Stamens 3--3.5 mm; filaments 1.8--2.2 mm; anthers ca. 1 mm. Style ca. 2.5 mm, slightly longer than ovary; stigma 3-lobed. Berry 5--8 mm in diam., many seeded. Seeds oblong, curved. Fl. Jun, fr. Aug--Sep.. * Forests, thickets, alpine grasslands; 2000--3500 m. SW Sichuan, NW Yunnan.. ...
Natural ProductsNatural Products
Ho, G. A.; Nouri, D. Tantillo, D. J. J. Org. Chem. 2005, 70, 5139-5143: The Cationic Cascade Route to Longifolene. Nouri, D. H.; Tantillo, D. J. Curr. Org. Chem. 2006, 10, 2055-2074: They Came from the Deep: Syntheses, Applications, and Biology of Ladderanes. Gutta, P.; Tantillo, D. J. J. Am. Chem. Soc. 2006, 128, 6172-6179: Theoretical Studies of Farnesyl Cation Cyclization: Pathways to Pentalenene. Gutta, P.; Tantillo, D. J. Org. Lett. 2007, 9, 1069-1071: A Promiscuous Proton in Taxadiene Biosynthesis?. Willenbring, D.; Tantillo, D. J. Russ. J. Gen. Chem. 2008, 78, 723-731 (Rossiiskii Khimicheskii Zhurnal 2007, 51, 49-55): "Mechanistic Possibilities for Oxetane Formation in the Biosynthesis of Taxols D Ring". Wang, S. C.; Tantillo, D. J. J. Org. Chem. 2008, 73, 1516-1523: Theoretical Studies on Synthetic and Biosynthetic Oxidopyrylium-Alkene Cycloadditions. Pericyclic Pathways to Intricarene. Tantillo, D. J. J. Phys. Org. Chem. 2008, 21, 561-570: Recent Excursions to the Lands ...
Yew Pine | ASPCAYew Pine | ASPCA
If you think that your animal is ill or may have ingested a poisonous substance, contact your local veterinarian or our 24-hour emergency poison hotline directly at 1-888-426-4435.
Yew: PollenwarndienstYew: Pollenwarndienst
Core competence of other disciplines are as well as cooperations with partners from science and industry essential to realize our projects and services in order to grant the best possible and innovative pollen information on a scientific basis. High-quality services, which we want to provide for free, are in need of different partnerships. We pay special attention to the preservation of our independence and objectivity and not to face our users with direct advertising.. ...
PlantFiles Pictures: Joshua Tree (Yucca brevifolia) by davePlantFiles Pictures: Joshua Tree (Yucca brevifolia) by dave
Welcome to the famous Daves Garden website. Join our friendly community that shares tips and ideas for gardens, along with seeds and plants.
Daily Ohio statesman (Columbus, Ohio : 1855), 1869-06-30 :: Ohio StatesmanDaily Ohio statesman (Columbus, Ohio : 1855), 1869-06-30 :: Ohio Statesman
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Ardbeg Corryvreckan 57.1%Ardbeg Corryvreckan 57.1%
Reviewed by Dave Broom and Martine Nouet. Awarded Recommended. Discussed in 9 topics. Dry with good extract. Loosens well with a drop of water showing grapefruit,ripe pear,a hint of malt then some yew. - more...
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TaxusPaclitaxelDrug-Eluting StentsCoronary RestenosisCardiovascular AgentsPlant PoisoningTubulin ModulatorsProsthesis DesignChromium AlloysAngioplasty, Balloon, CoronaryPrince Edward IslandNew South WalesTurner SyndromeFraudEmbryologyDocumentationSanitary EngineeringBathing BeachesHawksEncyclopedias as TopicParisRestaurantsWaterPublic-Private Sector PartnershipsCoxsackie and Adenovirus Receptor-Like Membrane ProteinInvestmentsAngioplasty, BalloonAdenoviridaeReceptors, VirusCardiac CatheterizationFloridaDeerNitrogen CompoundsPhysalisEntomophthoralesPinusNigeriaTransportationAppointments and SchedulesAmyloid beta-Protein PrecursorPrenatal CareObstetrics and Gynecology Department, HospitalAutomobile DrivingCitiesTravelEuropean UnionAzospirillum brasilenseArchaeoglobalesAutomobilesLoveBaltimorePhenylketonuriasWindNeonatal ScreeningBlood Specimen Collection
Taxus floridana (Florida Yew)Taxus floridana (Florida Yew)
Taxus Stents Deal Is Offered - tribunedigital-sunsentinelTaxus Stents Deal Is Offered - tribunedigital-sunsentinel
Boston Scientific: Taxus stent sales were off 25 percent during Q2 - MassDeviceBoston Scientific: Taxus stent sales were off 25 percent during Q2 - MassDevice
Taxus cuspidata Columnaris - Plant FinderTaxus cuspidata 'Columnaris' - Plant Finder
Taxus - WikipèdiaTaxus - Wikipèdia
New Study Suggests Better Patient Outcomes with CYPHER,Sirolimus-Eluting Coronary Stent than with Taxus Stent in,Real-World...New Study Suggests Better Patient Outcomes with CYPHER,Sirolimus-Eluting Coronary Stent than with Taxus Stent in,Real-World...
Taxus Baccata. - A DICTIONARY OF PRACTICAL MATERIA MEDICA By John Henry CLARKE, M.D. Presented by M di-TTaxus Baccata. - A DICTIONARY OF PRACTICAL MATERIA MEDICA By John Henry CLARKE, M.D. Presented by M di-T
Taxus Cardium Pharmaceuticals Group Inc CRXM Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated:...Taxus Cardium Pharmaceuticals Group Inc CRXM Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated:...
Medtronic Resolute® Drug-Eluting Stent Shows Superiority to Taxus® DES in Study of Patients with Coronary Artery...Medtronic Resolute® Drug-Eluting Stent Shows Superiority to Taxus® DES in Study of Patients with Coronary Artery...
The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear...The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear...
Sydney taxi CorruptionSydney taxi Corruption
Category:Taxidea taxus - Wikimedia CommonsCategory:Taxidea taxus - Wikimedia Commons
Taxis and PRT - ConnectedCitiesTaxis and PRT - ConnectedCities
Water Taxi Beach - WikipediaWater Taxi Beach - Wikipedia
Taxus Cardium | Investor Relations | News ReleaseTaxus Cardium | Investor Relations | News Release
Taxus Cardium | Investor Relations | News ReleaseTaxus Cardium | Investor Relations | News Release
Taxus - WikipediaTaxus - Wikipedia
Hailing a Taxi - The Washington PostHailing a Taxi - The Washington Post
Taxus fuana - WikipediaTaxus fuana - Wikipedia
Cortona: Taxis & Rental Cars - TripAdvisorCortona: Taxis & Rental Cars - TripAdvisor
Blurry taxis : Digital Photography ReviewBlurry taxis : Digital Photography Review
Top Taxi Booking App NigeriaTop Taxi Booking App Nigeria
Battery Swapping TaxisBattery Swapping Taxis
Taxi Driver Solidarity - The New York TimesTaxi Driver Solidarity - The New York Times
Freewing T-45 Daytime Taxi Test - YouTubeFreewing T-45 Daytime Taxi Test - YouTube
Bike Taxi in India - Future OpportunityBike Taxi in India - Future Opportunity
3 Ways to Use Taxis - wikiHow3 Ways to Use Taxis - wikiHow
Taxi (unrated) | Miami.com | Miami...'Taxi' (unrated) | Miami.com | Miami...
Jeremy Guthrie: Water taxis - Sun SentinelJeremy Guthrie: Water taxis - Sun Sentinel
Category:Water Taxi Beach - Wikimedia CommonsCategory:Water Taxi Beach - Wikimedia Commons
Branson Taxi: Season 1 - TV ReviewsBranson Taxi: Season 1 - TV Reviews
taxi News - Japan Real Time - WSJtaxi News - Japan Real Time - WSJ
Black Days For The London TaxiBlack Days For The London Taxi
Taiwan Taxi | Acer DesignTaiwan Taxi | Acer Design
Water Taxi | Travel + LeisureWater Taxi | Travel + Leisure
Taxi Driver - Spain Barcelona City 3D App StoredaTaxi Driver - Spain Barcelona City 3D App Store'da
Taxi Drivers How to Prevent Robbery | NIOSH | CDCTaxi Drivers How to Prevent Robbery | NIOSH | CDC
Transport Media Organise Taxi Branding For Langham LondonTransport Media Organise Taxi Branding For Langham London
Rapido Bike Taxi App on the App StoreRapido Bike Taxi App on the App Store
OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth CareGeographicals
TaxusPaclitaxelDrug-Eluting StentsCoronary RestenosisCardiovascular AgentsPlant PoisoningTubulin ModulatorsProsthesis DesignChromium AlloysAngioplasty, Balloon, CoronaryPrince Edward IslandNew South WalesTurner SyndromeFraudEmbryologyDocumentationSanitary EngineeringBathing BeachesHawksEncyclopedias as TopicParisRestaurantsWaterPublic-Private Sector PartnershipsCoxsackie and Adenovirus Receptor-Like Membrane ProteinInvestmentsAngioplasty, BalloonAdenoviridaeReceptors, VirusCardiac CatheterizationFloridaDeerNitrogen CompoundsPhysalisEntomophthoralesPinusNigeriaTransportationAppointments and SchedulesAmyloid beta-Protein PrecursorPrenatal CareObstetrics and Gynecology Department, HospitalAutomobile DrivingCitiesTravelEuropean UnionAzospirillum brasilenseArchaeoglobalesAutomobilesLoveBaltimorePhenylketonuriasWindNeonatal ScreeningBlood Specimen Collection
BaccataStentCuspidataBrevifoliaChinensisZuccTaxolExpress2WallichianaCardiumShrubTaxoidGenomeWikimedia CommonsGenus2018UberCity'sLimousine CommissionLondon TaxiFaresYellow taxisCompany'sDriverCabs3000London'sProtesting taxi driversParisRidesFerriesStreetsServiceServicesIconicHail a taxiLicensesPassengerCityIndiaBusesTimePeopleFleetBlack cabTraditional taxiGroupMobile appWorkTrustworthyYearsLoginBusinessOfficialsNewsBooking AppTaiwan TaxiNational taxiTouristsDrivenPublicDockRegulateJoomlaRanks
Baccata5
Stent3
  • Sales of Boston Scientific Corp. 's Taxus drug-eluting stent line fell 25 percent during the three months ended June 30, according to a detailed earnings report filed with the Securities and Exchange Commission. (massdevice.com)
  • MINNEAPOLIS--( BUSINESS WIRE )-- The Resolute ® drug-eluting stent (DES) from Medtronic, Inc. (NYSE: MDT), showed superiority to Boston Scientific Corp.'s Taxus ® DES on the primary endpoint of the RESOLUTE Japan clinical study: in-stent late lumen loss at eight months. (fiercehealthcare.com)
  • The primary endpoint of RESOLUTE Japan compared 100 patients treated with the Resolute DES to a historical control - specifically, eight-month in-stent late lumen loss for 135 patients in the ENDEAVOR IV clinical trial who received a Taxus DES. (fiercehealthcare.com)
Cuspidata1
Brevifolia3
Chinensis2
  • In the cell culture of Taxus chinensis, Taxuyunnanine C (Tc) is the primary taxoid. (edu.au)
  • Following the construction of an antisense RNA expression vector of 14OH from Taxus chinensis , the antisense 14OH cDNA (as 14OH ) was introduced into TM3 cells by Agrobacterium tumefaciens -mediated transformation. (up.edu)
Zucc2
Taxol2
  • Taxus suspension cell culture has the potential to provide a sustainable source of anticancer drug paclitaxel (Taxol ® ) and other taxoids. (edu.au)
  • These results indicated that the antisense RNA strategy is a useful tool in suppressing the expression of genes in Taxus and this method could be used to silence other important genes that divert Taxol pathway to side-route metabolites. (up.edu)
Express21
  • Included in that increase, however, was a $22 million "returns reserve adjustment" the company took during the second quarter of 2008 to compensate for the planned transition from the Taxus Express2 to the second-generation Taxus Liberté. (massdevice.com)
Wallichiana1
Cardium1
  • Taxus Cardium Pharmaceuticals Group Inc CRXM Pharmaceuticals Healthcare Deals and Alliances Profile provides you comprehensive data and trend analysis of the company's Mergers and Acquisitions MAs, partnerships and financings. (bioportfolio.com)
Shrub1
  • The yew, aka Taxus spp , is a tree / shrub that grows predominatly in wet , temperate climates. (everything2.com)
Taxoid2
  • To suppress taxoid 14β- hydroxylase gene ( 14OH ) expression in the Taxus × media TM3 cell line, antisense RNA inhibition approach was used in this study. (up.edu)
  • and Qui, De-You, "Antisense-induced suppression of taxoid 14β-hydroxylase gene expression in transgenic Taxus × media cells" (2011). (up.edu)
Genome1
  • Southern blot analysis of hygromycin phosphotransferase gene (HYG) revealed that this selection gene was integrated successfully into the genome of Taxus × media cells. (up.edu)
Wikimedia Commons1
  • Wikimedia Commons prepausa de documents multimèdia liures sus Taxus . (wikipedia.org)
Genus3
  • Taxus is a genus of small coniferous trees or shrubs in the yew family Taxaceae. (wikipedia.org)
  • Known to botanists as the conifer genus Taxus or yew, there is current consensus that there are eight species worldwide, occurring on various continents and in diverse climates. (mountauburn.org)
  • Taxus x × media , whenever you see the letter × between the genus ( Taxus ) and species ( media ) of a plant name that identifies this as a plant which had parentage from two different species, referred to as a hybrid. (mountauburn.org)
20181
  • Other potential rivals include crowd-funded eVolo, a firm based near Mannheim that has said it expects to receive special regulatory approval for its two-seat "multicopter" with 18 rotors to be used as flying taxis in pilot projects by 2018. (ndtv.com)
Uber22
City's7
  • Earlier this month Nissan unveiled its update of New York City's most iconic moving public space: the Taxi, only a year after New York City Taxi and Limousine Commission selected the automaker, after an extremely competitive two-year bid selection process. (metropolismag.com)
  • Understanding that the NYC Taxi is a major element of the city's brand, the design team gave the brand the face-lift it deserves. (metropolismag.com)
  • The first bomb blew up at 1:05 p.m. yesterday in one of the city's trademark yellow-and-black taxis, which was parked at an intersection in the Mumba Devi neighborhood. (baltimoresun.com)
  • Hong Kong - Hong Kong saw its first electric taxis hit the streets on Saturday in a step towards reducing the city's high levels of roadside pollution. (news24.com)
  • Shanghai's transportation authority also plans to enlist the city's taxi dispatch centers to supervise and regulate taxi-hailing apps. (chinadaily.com.cn)
  • During a visit to Mbandaka, the AP attended a workshop run by the government and the World Health Organization for 300 of the city's estimated 4,000 taxi drivers. (morningjournal.com)
  • Earlier this year, the city's Taxi and Limousine Commission said there are 545 money-grubbing hacks who pulled off the scam between 50 and 499 times - and a disturbing 88 who did it more than 500 times. (villagevoice.com)
Limousine Commission3
London Taxi5
  • London Taxi will get you home or to work or wherever you need to be with a just click to hail a private car directly from your location. (apple.com)
  • You can specify an 8 seater, estate or just a normal saloon to take you away and in spite it being called London Taxi, this app is not just restricted to London. (apple.com)
  • Let London Taxi take you securely, economically and comfortably to your destination. (apple.com)
  • London Taxi comes from the makers of the most downloaded London Commuter app ever, London Tube Map (so you know you're in safe hands! (apple.com)
  • The new Austin FX4 was not just the first London taxi to be fitted with four doors for, together with the Routemaster bus, it was symbolic of post-war change in the capital. (telegraph.co.uk)
Fares5
  • He is a pretty bad taxi driver, unsure of the routes to well-known Tehran landmarks and less than diligent about collecting fares and delivering customers to their destinations. (miamiherald.com)
  • Taxi fares are basically made up of a starting fee and then a per-kilometre charge (listed here). (inyourpocket.com)
  • Taxi Booking is suitable for - Metered taxi services, Limo and Private hire pre-booked fixed fares, Hourly car hire, Shuttle and Bus ticket sales. (joomla.org)
  • The six-day strike had left commuters stranded across the country, with taxis taking only emergency fares for disabled people or those needing to get to hospitals, and led to scuffles in Rome as protesters clashed with police. (thestar.com.my)
  • Santaco's highest decision-making body‚ Management Council (Manco)‚ has decided at its specially convened meeting that taxi fares for local and long-distance operations will increase‚" the organisation said. (timeslive.co.za)
Yellow taxis1
Company's1
  • B MC had developed a replacement model, codenamed ADO39, but this was cancelled following the company's merger with Leyland, and the now virtually iconic taxi would have to continue in production for several more years. (telegraph.co.uk)
Driver24
  • Keep your hand raised until a taxi driver spots you and pull over. (wikihow.com)
  • Make eye contact with the driver when your taxi pulls over. (wikihow.com)
  • Once your driver has stopped, approach the taxi and make direct eye contact as you do so. (wikihow.com)
  • Open the backseat door and enter the taxi, where you can tell the driver your destination. (wikihow.com)
  • All he needed was a taxi and the driver to go with it. (fanfiction.net)
  • Johannesburg - A taxi driver who had been using somebody else's name on his licence was cornered and arrested in Ivory Park, east of Johannesburg on Wednesday. (news24.com)
  • The taxi driver turned out to be a licenceless Mozambican national who had been passing himself off as Ringani for years. (news24.com)
  • The team approached the product design of the Taxi by considering the passenger and the driver. (metropolismag.com)
  • A taxi licence in Rome is worth €150,000 (RM704,794), but the NCC pays ten times less elsewhere," said Gabriele, 52, who has been a taxi driver since 2011 and did not want to give his surname. (thestar.com.my)
  • We are a public service and we're independent while they're defending multi-nationals,' said taxi driver Marta Fernandez, 42, during the protest which shut off traffic for at least two hours. (voanews.com)
  • Lal Sahab Singh, a taxi driver whose white clothes were spotted with blood, was yards away when the bomb exploded. (baltimoresun.com)
  • Malele said the driver carried a responsibility to ensure the taxi was disinfected, riders sanitised and ensure the windows were semi-ajar, and this would ensure there was accountability all around to ensure commuters and drivers were safe when commuting. (iol.co.za)
  • The driver will also shut the door when you leave the taxi. (hubpages.com)
  • A New York City taxi driver who fatally struck a pedestrian in Manhattan in November had been working more than 15 hours. (wsj.com)
  • Officers took the two into custody after seeing that the pair was wanted on a variety of criminal offenses but let taxi driver Abdullah Sönmez go, according to reports. (hurriyetdailynews.com)
  • Not long ago there were reports of a taxi driver taking an Arab tourist from Kadıköy on the Asian side of the city, over the Bosphorus Bridge to the European side, and back over the bridge to the Sabiha Gökçen Airport on the Asian side. (hurriyetdailynews.com)
  • In another report, a taxi driver was accused of trying to kick out the husband and kidnap his wife. (hurriyetdailynews.com)
  • A taxi driver who was embroiled in a road rage incident punched a motorcyclist so severely that it left him with a permanent eye injury. (yahoo.com)
  • A motorcycle taxi driver carries a passenger through the streets of Mbandaka, Congo. (morningjournal.com)
  • Despite his worries, the taxi driver in Mbandaka city never presented himself to health officials, who are vaccinating everyone who's had direct contact with a sick person and then contacts of those people, too. (morningjournal.com)
  • Jens Stoltenberg: Norway's prime minister works as taxi driver for afternoon. (slate.com)
  • In what he described as an effort to hear from real Norwegians, Stoltenberg dressed up as a taxi driver and spent an afternoon driving people around Oslo. (slate.com)
  • Why did you decide to become a licensed taxi driver, instead of just a taxi passenger? (seriouseats.com)
  • After the November 15th Metropolitan Transit System Taxicab Advisory Committee (MTS-TAC) election, the 800-member strong taxi driver association plans to once again bring up the issue of lease fees through their new elected representatives. (kpbs.org)
Cabs5
30001
  • Mathematicians at the MIT CSAIL computer lab have developed a new algorithm they say could eliminate allow 3000 carpooling vehicles to do the work of 14,000 taxis. (gas2.org)
London's1
Protesting taxi drivers1
  • Among travelers caught up in the chaos was U.S. rock singer Courtney Love, widow of late Nirvana lead singer Kurt Cobain, who wrote in a Tweet appeal to the French president that her car had come under siege by protesting taxi drivers. (reuters.com)
Paris7
  • In concept, Water Taxi Beach is similar to Paris Beach in Paris , France . (wikipedia.org)
  • Taxis drivers block a highway outside Paris, as they take part in a demonstration to protest against the growing number of minicabs, known in France as Voitures de Tourisme avec Chauffeurs (VTC). (sfgate.com)
  • Taxi drivers in London, Paris and other European capitals. (sfgate.com)
  • A yellow ribbon reading "Taxi on strike" is seen on a Paris taxi which is taking part in a demonstration near the Eiffel Tower, in Paris, on Wednesday. (sfgate.com)
  • PARIS (Reuters) - France ordered a nationwide clampdown on UberPOP on Thursday, siding with taxi drivers who blockaded major transport hubs in angry protests against the popular online ride-sharing service. (reuters.com)
  • Creative ways to beat city traffic are always appreciated, and Paris is taking it to the next level with new flying water taxis. (matadornetwork.com)
  • If near field communication (NFC) technology can be used to help commuters pay for their bus journeys in Paris , then why not let taxi patrons in Taiwan use it to book their next ride? (springwise.com)
Rides9
  • This Taxi Booking App app allow the users to get a safe, reliable and classy rides with the simple taps. (slideshare.net)
  • Taxi apps are those apps which allows the users to get a safe, reliable and classy rides with the fingertips of their hands. (slideshare.net)
  • It's a win for the young startup, especially in light of the TLC's on-again, off-again battles with e-hailing services and the recent kibosh it put on another sharing service, SideCar, which used private vehicles, not taxis, to provide shared rides. (crainsnewyork.com)
  • He tested his sense that people would be motivated to share rides by trying to hand out dollar bills to travelers at the head of the taxi line at Penn Station if they would stand aside for a few minutes and not take the next cab. (crainsnewyork.com)
  • The latest taxi apps offer fast rides to the customers and help them to reach their destinations well in time. (selfgrowth.com)
  • The taxi apps also offer shared rides which enable them to cut down on expenses while at the same time get the best quality taxi services for their needs. (selfgrowth.com)
  • The number of taxi rides is growing - overwhelmingly so for people in poor neighborhoods - as fire officials wrestle with more calls and limited resources. (azcentral.com)
  • The number of taxi calls by Phoenix fire has grown steadily in recent years, both in numbers and in percentage of taxi rides compared with all dispatches. (azcentral.com)
  • The researchers used data from over 3 million NYC taxi rides to create a simulation of an average day for taxi drivers. (popularmechanics.com)
Ferries1
  • The beach concept was created in 2005 as an experiment in community and economic development by New York Water Taxi to attract Manhattanites to Long Island City and to make weekend ferries serving the new residential high-rises near the beach financially viable. (wikipedia.org)
Streets1
  • As a result, many taxi drivers cruise the streets with their eye on a collection of cell phones dotted on their dashboards running various apps while searching for big-ticket bids, which poses potential safety hazards. (chinadaily.com.cn)
Service19
Services15
  • 2. Vice-President and President of Taxi Industry Services Association, respectively. (google.com)
  • Many people took the operating companies' offer to trade-in their cars and invest in taxis and PRT services for which they get a big discount. (google.com)
  • Launch your own Nigeria taxi booking app for transportation services. (slideshare.net)
  • The fledgling union for Chicago's taxi drivers complained, citing an ordinance barring anyone but taxicabs and limousine services from serving the airports. (nytimes.com)
  • Taxi drivers hold a banner during a strike action in protest of unliscensed taxi-type-services in Barcelona on Wednesday. (sfgate.com)
  • With Taxi Booking Light you can start selling your transportation services on your website in minutes. (joomla.org)
  • Founded in 2002, New York Water Taxi has continuously expanded its routes and increased its fleet while delivering spectacular views for a price that shames the car services. (nymag.com)
  • More than a thousand Spanish taxi drivers blocked a central Madrid boulevard on Thursday, beeping horns and setting off firecrackers, to protest plans to open the country to greater competition from ride-hailing and car-sharing services. (voanews.com)
  • SHANGHAI, Feb 9 (Reuters) - Chinese ride hailing giant Didi Chuxing will set up a venture with SoftBank Group Corp to provide ride-hailing and other services for the Japanese taxi industry, the companies said in a statement on Friday. (reuters.com)
  • There are also plans to look at potential routes for the proposed water taxi services, he added. (thefreedictionary.com)
  • Munich-based Lilium, backed by investors who include Skype co-founder Niklas Zennstrom, said the planned five-seater jet, which will be capable of vertical take-off and landing, could be used for urban air taxi and ride-sharing services. (ndtv.com)
  • Such factors have certainly increased the demand for the services that are offered by taxi app development companies. (selfgrowth.com)
  • Here are some of the reasons why companies looking to be a part of online taxi booking services are currently using the expertise offered by the taxi app development firms. (selfgrowth.com)
  • Most of the taxi apps are light, easy to use and deliver fast services which has enabled them to become very popular within a short time. (selfgrowth.com)
  • The best thing about taxi apps is that both the consumers and taxi drivers are on the same page when it comes to their services as well as the prices that they need to pay for a ride. (selfgrowth.com)
Iconic1
Hail a taxi3
  • When you're ready to hail a taxi, stand at the edge of the sidewalk away from oncoming cars. (wikihow.com)
  • If you make it easy for drivers to see you, you will hail a taxi faster. (wikihow.com)
  • Ask at your hotel for help to write the location to where you want to go, then go hail a taxi on the street, as it will be cheaper than booking one. (hubpages.com)
Licenses1
  • Slackening the rules would pitch the heavily-regulated taxi sector, which requires licenses and closely monitored quality and safety controls, against untested drivers which operate with little, or no, restrictions, taxi unions say. (voanews.com)
Passenger1
  • The jet, whose power consumption per km is comparable to an electric car, could offer passenger flights at prices comparable to normal taxis but with speeds five times faster, Lilium said. (ndtv.com)
City20
  • Water Taxi Beach was an artificial temporary beach operated from 2005 to 2010 on a wharf on the East River in the Hunters Point section of Long Island City , in the New York City borough of Queens . (wikipedia.org)
  • There are taxis in Cortona, but they don't just roam around like in a large city such as Rome. (tripadvisor.co.uk)
  • Eager to reverse the trend, taxi drivers in Chicago and other cities are for the first time seeking to form a national taxi drivers' union - not just to gain leverage against UberX but also to pressure city officials and taxi companies to heed their concerns. (nytimes.com)
  • The powerful taxi drivers' union in New York City, with 17,000 members, is spearheading this effort, bringing its organizing expertise to Chicago, where it is pushing to unionize thousands of drivers and to link up with drivers' unions in Philadelphia, Miami, Houston, northern Maryland and Austin, Tex. (nytimes.com)
  • One snag these unionization plans face is that taxi drivers are usually independent contractors who are barred by antitrust law from colluding to set prices (although they can lobby city officials to grant fare increases). (nytimes.com)
  • One recent Sunday afternoon, three leaders of the New York City Taxi Workers Alliance met with 10 Chicago taxi drivers on Chicago's North Side to strategize about expanding the union here and trying to halt UberX's expansion. (nytimes.com)
  • South Korea's transport ministry and Seoul City conducted a test-run of a drone taxi - capable of carrying two people, with a demonstration in Seoul on Wednesday. (reuters.com)
  • The new Taxi will start appearing on New York City roads on October 31, 2013. (metropolismag.com)
  • I've hailed my fair share of taxis in New York City, which are mostly Crown Victorias. (gas2.org)
  • Cabdrivers crusaded yesterday to get the city to add a surcharge to taxi meters to offset rising gas prices. (nypost.com)
  • He called for more charging stations around the city to encourage taxi drivers to go electric - BYD said it is setting up 47 chargers in nine charging locations near car parks. (news24.com)
  • Summary: New Delhi [India], June 26 (ANI): Minister of State for Shipping, Mansukh Mandaviya on Wednesday inspected the Sonia Vihar site for proposed Yamuna Water Taxi Project of Inland Waterways Authority of India (IWAI) here said that the project will boost tourism in a sustainable way and reduce traffic congestion in the city. (thefreedictionary.com)
  • OKLAHOMA CITY Boathouse Foundation Executive Director Mike Knopp and Bricktown Water Taxi General Manager Chad Huntington have been talking for several years about connecting their two areas. (thefreedictionary.com)
  • The City of Memphis has landed an $800,000 U.S. Department of Transportation grant to put water taxis in the Mississippi River but convincing city officials to come up with a 20 percent match for the project could be a tough sell, The Commercial Appeal reports . (bizjournals.com)
  • These distinctive blue Toyotas are the most common taxis in the city, as well as the most reputable. (travbuddy.com)
  • Hundreds are being vaccinated in Congo's deadly Ebola outbreak, but busy taxi drivers who might be ferrying the sick in an infected city of more than 1 million argue they are on the front lines as well and should receive the vaccine. (morningjournal.com)
  • Propped against his motorcycle taxi outside a hospital in the city affected by Congo's latest deadly Ebola outbreak, Jean Cedric waved a hand in the air, showing his fear about the risks of his job. (morningjournal.com)
  • With few cars in the vibrant city on the Congo River, the majority of residents rely on motorcycle taxis as their primary mode of transport. (morningjournal.com)
  • Taxi vouchers are paid for by the city and cost a fraction of an ambulance ride. (azcentral.com)
  • Thanks to them, I stumbled upon some wonderful off-the-radar spots (I haven't found a steak that's come close since), but I wanted to see how the taxi adventures would translate in a city where drivers, and food, come from all over the world. (seriouseats.com)
India2
  • Owing to mobility demand, the concept of bike taxi is gaining popularity in India. (slideshare.net)
  • BOMBAY, India - Two powerful bombs concealed in parked taxis exploded yesterday in the heart of Bombay, India's commercial capital, killing 45 people and wounding at least 135. (baltimoresun.com)
Buses1
  • However, taxis are often the only way of getting around after midnight because trains and buses have stopped. (hubpages.com)
Time11
  • In the mean time please do not forget to ask yourself, how the taxi mafia managed to silence and sabotage far too many inquiries and outcomes mentioned in The Power of the Taxi Mafia and in the Sydney Morning Herald! (google.com)
  • Your first time riding in a taxi can be a little confusing. (wikihow.com)
  • This allows taxi drivers to know where potential customers are in real time. (acer.com)
  • This time the terrorists used taxis, and last time they used scooters. (baltimoresun.com)
  • You can choose the Time and place from where you want to borrow the taxi. (issuu.com)
  • There's also a time charge if the speed drops below 10km/h, or if the taxi stops. (hubpages.com)
  • The very idea behind the whole business is to merging mobile applications with traditional taxi business so that customers can book taxis online any time they want. (selfgrowth.com)
  • One of the main reasons why taxi apps have become so much popular in such a short time is that they make use of the best quality app development technologies in order to create apps which can be extremely useful to the consumers. (selfgrowth.com)
  • Our company looking for a group of team build taxi software web application , and hosted on our server , also we need written for the program manual technical user ,give support plus maintenance for managing Development must complete in frame time 7-8 weeks with test etc. (freelancer.com)
  • The algorithm can even predict areas where taxi usage will be high in the future, and send taxis to that area ahead of time for faster pickups. (popularmechanics.com)
  • For the first time, taxi drivers will get representation on a committee that advises the Metropolitan Transit System on taxi regulations. (kpbs.org)
People10
  • Toyota Motor's Japan Taxi, born in a government committee and designed to be an all-things-to-all-people cab, has become a high-priced icon of Tokyo's budget-busting 2020 Olympic and Paralympic Games. (japantimes.co.jp)
  • Taxis are expensive, so don't use them unless you are with 3 other people to share the costs and you are trying to out run a tsunami. (hubpages.com)
  • Taxis are used by millions of people all around the world and they are widely preferred due to the simple and hassle-free traveling experience that they can provide. (selfgrowth.com)
  • Even today, taxi transportation forms an essential component of the regular public conveyance modes that are used by various people. (selfgrowth.com)
  • A taxi company app can not only make it easier for people to find taxis even during the busy hours of the day but it can also render it much easier and convenient. (selfgrowth.com)
  • They are particularly useful for people who tend to use taxis on a frequent basis. (selfgrowth.com)
  • Gone are the days when people had to stand in long queues in order to find the taxi that they are looking for. (selfgrowth.com)
  • Fwelo told the all-male group that she saw too many taxi drivers "die from fever" during the much larger West Africa outbreak four years ago that killed more than 11,000 people in Guinea, Liberia and Sierra Leone. (morningjournal.com)
  • She took a communal taxi via Liberia's capital Monrovia, exposing five other people to the virus who later contracted and died of the Ebola. (foxnews.com)
  • On the Greek island of Zakynthos (population approximately 35,000), at least 600 people (including taxi drivers and recreational hunters) have falsely registered themselves as blind and are collecting disability payments (of at least 350 euros, about $462, per month) from Greece's cash-strapped government. (care2.com)
Fleet2
Black cab1
  • We don't care if it is a NYC yellow cab, a London black cab or a Havanna Coco Taxi as long as it's a taxi and there is blur in the image. (dpreview.com)
Traditional taxi1
  • Mobile taxi-booking apps have currently posed as a major edge for the traditional taxi business. (selfgrowth.com)
Group6
Mobile app1
Work7
  • Taxi is full of wry jokes, surprising incidents and allusions to Mr. Panahi's earlier work. (miamiherald.com)
  • Taxi , though, happens to be the work of a great one, one of the most humane and imaginative practitioners of the art currently working. (miamiherald.com)
  • This is a payment plugin to accept Credit Cards through Authorize.net This payment plugin is for Taxi Booking extension for Joomla and will not work on it's own or for any other extension. (joomla.org)
  • But she had urged them to find a way to return to work, saying "the taxi drivers are a calling card for tourists and foreigners" stranded at airports, stations and hotels. (thestar.com.my)
  • How Stafford Taxis Work? (issuu.com)
  • Effective from March 1, taxi drivers that reject roadside hailing customers are subject to fines worth 200 yuan ($32) and 15 days' suspension of their work permit. (chinadaily.com.cn)
  • But if parliament doesn't work on this issue and the justice system hands down a different ruling [not in favor of the taxi drivers], our patience will have run out. (hurriyetdailynews.com)
Trustworthy1
  • Furthermore, if you're not familiar with Jakarta it's always best to take the BlueBird because not all taxis are trustworthy (and sometimes not even safe). (travbuddy.com)
Years1
  • S ixty years ago, sales commenced of a taxi so radical in design that not a few cabbies in the capital regarded it with a degree of suspicion. (telegraph.co.uk)
Login1
  • 4. Features of taxi app  Easy Login and Registration  User-friendly interface  Multiple languages  Multiple currencies  Flexible payment options  Reviews and feedback  Customer care support etc. (slideshare.net)
Business4
Officials3
  • Mamabolo said monitoring would be done by the taxi association leaders and government officials deployed to ranks. (iol.co.za)
  • He said the marshals and managers would be trained and monitored to ensure the whole operation was above board, such as ensuring they adhered to what is required on the app, and there will be government officials to oversee that this happens as well as taxi industry co-ordinators to add support. (iol.co.za)
  • While officials say that anyone, including taxi drivers, who have had contact with an Ebola case or with one of those contacts will be vaccinated, the drivers are harder to track down because they're always on the move. (morningjournal.com)
News1
Booking App1
Taiwan Taxi2
  • A partnership between Nokia and Taiwan Taxi enables those with NFC-enabled phones to use that technology to book their next ride. (springwise.com)
  • That, indeed, is now possible thanks to a partnership between Nokia and Taiwan Taxi. (springwise.com)
National taxi3
  • The A.F.L.-C.I.O. supports the idea of a national taxi drivers' union as part of its broader strategy to reverse decades of decline in union membership and power. (nytimes.com)
  • National Taxi Alliance spokesperson Theo Malele said they were elated that the government had come in to reinforce the management in the taxi industry to ensure all commuting masses were safe when using transport. (iol.co.za)
  • The South African National Taxi Council (Santaco) has announced taxi fare increases between R1 and R10 for local trips and R1 to R20 for long distance journeys from August 1. (timeslive.co.za)
Tourists1
Driven3
  • It's definitely a United Nations," said Karen Chamberlain, who has driven a taxi in Chicago for two decades. (nytimes.com)
  • The Nissan design, the NV200 Taxi, is the result of a research-driven and cross-disciplinary collaboration of The Cooper-Hewitt National Design Museum , the Design Trust for Public Space , and Smart Design . (metropolismag.com)
  • They do not want to ride old taxis driven by rude drivers anymore. (hurriyetdailynews.com)
Public10
Dock1
Regulate1
  • Thailand introduced the law in 2005 to regulate Two-wheelers taxi and become the first country in the world to do so. (slideshare.net)
Joomla3
  • Taxi Booking Light is a lightweight version of the famous Taxi Booking for Joomla extension. (joomla.org)
  • Taxi Booking Light has the same front end booking form as Taxi Booking for Joomla, as well as a back-end management panel for Cars, Settings and Orders. (joomla.org)
  • From the creators of Taxi Booking for Joomla here is Share Cost - crowdfunding for Joomla. (joomla.org)
Ranks2
  • More stringent measures to ensure compliance with lockdown regulations in taxi ranks have been introduced. (iol.co.za)
  • Commuter Maureen Peta said this calmed down commuters who were feeling unsettled, and showed some seriousness to ensure ranks and taxis were not areas of danger as they had to use them daily as numbers go up in infections. (iol.co.za)
Battery Swapping Taxis
Battery Swapping Taxis (psfk.com)
Taiwan Taxi | Acer Design
Taiwan Taxi | Acer Design (acer.com)
Vaya Africa launches electric ride-hail taxi network
Vaya Africa launches electric ride-hail taxi network (au.finance.yahoo.com)
Decision to suspend taxi operations elicits mixed feelings - 'Unreasonable', says Kuwaiti citizen - ARAB TIMES - KUWAIT NEWS
Decision to suspend taxi operations elicits mixed feelings - 'Unreasonable', says Kuwaiti citizen - ARAB TIMES - KUWAIT NEWS (arabtimesonline.com)
MIGHTY JAM ROCK-SOUND BACTERIA #1 - RIDDIM TAXI
MIGHTY JAM ROCK-SOUND BACTERIA #1 - RIDDIM TAXI (riddimtaxi.com)
Racist slurs directed at Halifax taxi driver | CTV News
Racist slurs directed at Halifax taxi driver | CTV News (atlantic.ctvnews.ca)
Category:Taxidea taxus - Wikimedia Commons
Category:Taxidea taxus - Wikimedia Commons (commons.wikimedia.org)
An expert travel guide to Budapest | Telegraph Travel
An expert travel guide to Budapest | Telegraph Travel (telegraph.co.uk)
Coronavirus: Chance to contain outbreak is 'narrowing' says WHO
Coronavirus: Chance to contain outbreak is 'narrowing' says WHO (telegraph.co.uk)
Transportation in New York City - Wikipedia
Transportation in New York City - Wikipedia (en.wikipedia.org)
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Coffs Harbour - Wikipedia (en.wikipedia.org)
7 Ways Tech Made Your Life Better in 2014 | Money
7 Ways Tech Made Your Life Better in 2014 | Money (time.com)
Weird and wonderful world of creepy-crawlies | New Scientist
Weird and wonderful world of creepy-crawlies | New Scientist (newscientist.com)
New beetle species bites army ant's butt and hitches a ride | New Scientist
New beetle species bites army ant's butt and hitches a ride | New Scientist (newscientist.com)
Charlie's Angels (1977), Season 5 on iTunes
Charlie's Angels (1977), Season 5 on iTunes (itunes.apple.com)
Guide to Meeting & Event Planning in Grand County, CO
Guide to Meeting & Event Planning in Grand County, CO (cvent.com)
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Guide to Meeting & Event Planning in Franklin, TN (cvent.com)
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Guide to Meeting & Event Planning in Iowa City/Coralville, IA (cvent.com)
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Guide to Meeting & Event Planning in Phuket, Thailand (cvent.com)
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Guide to Meeting & Event Planning in Salt Lake, UT (cvent.com)
France: Tipping & Etiquette - TripAdvisor
France: Tipping & Etiquette - TripAdvisor (tripadvisor.co.uk)
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Guide to Meeting & Event Planning in Valley Forge - Montgomery County, PA (cvent.com)
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Guide to Meeting & Event Planning in New York City, NY (cvent.com)
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Guide to Meeting & Event Planning in Philadelphia, PA (cvent.com)
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Guide to Meeting & Event Planning in Fort Worth, TX (cvent.com)
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Guide to Meeting & Event Planning in Manchester, England (cvent.com)
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Guide to Meeting & Event Planning in St. Louis, MO (cvent.com)
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Guide to Meeting & Event Planning in Istanbul, Turkey (cvent.com)
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Guide to Meeting & Event Planning in Anaheim, CA (cvent.com)
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Guide to Meeting & Event Planning in Kansas City, MO (cvent.com)
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Guide to Meeting & Event Planning in Melbourne, Australia (cvent.com)
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Guide to Meeting & Event Planning in Stockholm, Sweden (cvent.com)
Vancouver Hotel Transportation | Directions & Map | Four Seasons Hotel
Vancouver Hotel Transportation | Directions & Map | Four Seasons Hotel (fourseasons.com)
Guide to Meeting & Event Planning in Riyadh, Saudi Arabia
Guide to Meeting & Event Planning in Riyadh, Saudi Arabia (cvent.com)
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Guide to Meeting & Event Planning in Arosa, Switzerland (cvent.com)