Tartrazine
Azo Compounds
Microchemistry
Drug Eruptions
Pseudolymphoma
Acute Generalized Exanthematous Pustulosis
Exanthema
Trimethoprim-Sulfamethoxazole Combination
Skin Diseases, Vesiculobullous
Skin Diseases
Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice. (1/15)
Secretions of Paneth, intermediate and goblet cells have been implicated in innate intestinal host defense. We have investigated the role of T cells in effecting alterations in small intestinal epithelial cell populations induced by infection with the nematode Trichinella spiralis. Small intestinal tissue sections from euthymic and athymic (nude) mice, and mice with combined deficiency in T-cell receptor beta and delta genes [TCR(beta/delta)-/-] infected orally with T. spiralis larvae, were examined by electron microscopy and after histochemical and lineage-specific immunohistochemical staining. Compared with uninfected controls, Paneth and intermediate cell numbers increased significantly in infected euthymic and nude mice but not infected TCR(beta/delta)-/- mice. Transfer of mesenteric lymph node cells before infection led to an increase in Paneth and intermediate cells in TCR(beta/delta)-/- mice. In infected euthymic mice, Paneth cells and intermediate cells expressed cryptdins (alpha-defensins) but not intestinal trefoil factor (ITF), and goblet cells expressed ITF but not cryptdins. In conclusion, a unique, likely thymic-independent population of mucosal T cells modulates innate small intestinal host defense in mice by increasing the number of Paneth and intermediate cells in response to T. spiralis infection. (+info)Tartrazine in atopic eczema. (2/15)
Multiple double blind placebo controlled challenges with tartrazine 50 mg (three challenges) and glucose placebo (three challenges) were performed in 12 children with atopic eczema aged 1 to 6 years. The children were selected on the basis of severity (regular clinic attenders) and a parental history that tartrazine provoked worsening of the eczema. In only one patient did the three tartrazine challenge periods correspond with the highest symptom scores or the highest physician observer scores, and the probability of this occurring by chance in one or more patients out of 12 was 0.46. In this sample we were unable to confirm intolerance to tartrazine in 11 out of 12 patients. (+info)Prolonged use of the food dye tartrazine (FD&C yellow no 5) and its effects on the gastric mucosa of Wistar rats. (3/15)
Tartrazine is one of the most widely used artificial foods, drugs and cosmetic dyes. It is a nitrous derivative and is known to cause allergic reactions such as asthma and urticaria, as well as having been the focus of studies on mutagenesis and carcinogenesis due to its transformation into aromatic amine sulfanilic acid after being metabolized by the gastrointestinal microflora. 45 male Wistar rats were assigned to a control group (A) or a treatment one (B). The treatment group received 7.5 mg x kg(-1) x day(-1) of tartrazine daily in drinking water offered ad libitum for ten months from weaning to the age of twelve months. There was a significant increase in the number of lymphocytes and eosinophils of the gastric antrum mucosa. No carcinogenetic changes in any gastric area were observed during the study. As tartrazine belongs to the azo class, it is still a possible food carcinogen. Other studies with different doses and schedules, observing their effects associated to other carcinogens should be carried out if their safe use is to be recommended. (+info)Sodium salicylate sensitivity in an asthmatic patient with aspirin sensitivity. (4/15)
Non-acetylated salicylates have been recommended for use as alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs) in aspirin and/or tartrazine-sensitive patients. We experienced a case of an aspirin-sensitive asthmatic patient who developed a broncho-obstructive reaction after taking 100 mg of sodium salicylate. The result of this study suggests that sodium salicylate may cross-react with aspirin in aspirin-and tartrazine-sensitive patients. (+info)Matrix remodeling during intervertebral disc growth and degeneration detected by multichromatic FAST staining. (5/15)
(+info)Toxicity of xanthene food dyes by inhibition of human drug-metabolizing enzymes in a noncompetitive manner. (6/15)
(+info)Effect of artificial food colours on childhood behaviour. (7/15)
We performed an objective evaluation of 39 children whose behaviour was observed by their parents to improve on an artificial food additive free diet and to deteriorate with dietary lapses. Only 19 children completed a double blind placebo controlled challenge study with artificial food colours. In these children food colours were shown to have an adverse effect on a daily Conners' rating of behaviour, but most parents could not detect these changes. A pharmacological mechanism of food additive intolerance is proposed to explain these effects. (+info)Development of an ultrasensitive immunoassay for detecting tartrazine. (8/15)
(+info)Tartrazine is a synthetic food coloring agent, also known as E number E102. It is a yellow dye derived from coal tar and is primarily used in the food industry to add or restore color. Tartrazine can be found in various products such as candies, desserts, beverages, sauces, and baked goods.
In addition to its use in food, tartrazine is also employed in cosmetics, personal care items, and pharmaceuticals. It serves as a coloring agent and can help improve the appearance of these products. However, some people may experience allergic reactions or sensitivities to tartrazine, which can result in symptoms like hives, itching, or swelling.
It is essential to note that tartrazine has been approved for use by regulatory bodies worldwide, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). However, these organizations recommend limiting its usage in food products due to potential health concerns.
Food coloring agents, also known as food dyes, are substances that are added to foods and beverages to improve or modify their color. They are typically made from synthetic chemicals, although some are derived from natural sources. Food coloring agents are subject to regulation by the U.S. Food and Drug Administration (FDA) and other regulatory bodies to ensure their safety.
Food coloring agents are used for a variety of reasons, including:
* Making foods look more appealing or attractive
* Restoring the natural color of foods that has been lost during processing
* Helping consumers identify products, such as flavors or varieties of candy
* Ensuring consistency in the color of a product from batch to batch
Some common food coloring agents include:
* Blue 1 (Brilliant Blue)
* Blue 2 (Indigo Carmine)
* Green 3 (Fast Green FCF)
* Red 3 (Erythrosine)
* Red 40 (Allura Red)
* Yellow 5 (Tartrazine)
* Yellow 6 (Sunset Yellow)
It is important to note that some people may be sensitive or allergic to certain food coloring agents and may experience adverse reactions after consuming them. Additionally, there has been some concern about the potential health effects of artificial food dyes, although current research does not support a strong link between their consumption and negative health outcomes in the general population.
Azo compounds are organic compounds characterized by the presence of one or more azo groups (-N=N-) in their molecular structure. The term "azo" is derived from the Greek word "azō," meaning "to boil" or "to sparkle," which refers to the brightly colored nature of many azo compounds.
These compounds are synthesized by the reaction between aromatic amines and nitrous acid or its derivatives, resulting in the formation of diazonium salts, which then react with another aromatic compound containing an active methylene group to form azo compounds.
Azo compounds have diverse applications across various industries, including dyes, pigments, pharmaceuticals, and agrochemicals. They are known for their vibrant colors, making them widely used as colorants in textiles, leather, paper, and food products. In addition, some azo compounds exhibit unique chemical properties, such as solubility, stability, and reactivity, which make them valuable intermediates in the synthesis of various organic compounds.
However, certain azo compounds have been found to pose health risks due to their potential carcinogenicity and mutagenicity. As a result, regulations have been imposed on their use in consumer products, particularly those intended for oral consumption or direct skin contact.
I'm sorry for any confusion, but "Microchemistry" is not a commonly used term in medicine. It is, however, a branch of chemistry that deals with the separation, identification, and analysis of chemical substances in minute quantities. This field can be applied in various scientific disciplines, including forensic science, environmental science, and materials science.
In the medical field, you might encounter similar concepts under terms like "microanalysis" or "clinical chemistry," which refer to the identification and measurement of chemical components in body fluids (like blood or urine) for diagnostic purposes. But again, "Microchemistry" is not a standard term used in this context.
A "drug eruption" is a general term used to describe an adverse skin reaction that occurs as a result of taking a medication. These reactions can vary in severity and appearance, and may include symptoms such as rash, hives, itching, redness, blistering, or peeling of the skin. In some cases, drug eruptions can also cause systemic symptoms such as fever, fatigue, or joint pain.
The exact mechanism by which drugs cause eruptions is not fully understood, but it is thought to involve an abnormal immune response to the medication. There are many different types of drug eruptions, including morphilliform rashes, urticaria (hives), fixed drug eruptions, and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), which is a severe and potentially life-threatening reaction.
If you suspect that you are experiencing a drug eruption, it is important to seek medical attention promptly. Your healthcare provider can help determine the cause of the reaction and recommend appropriate treatment. In some cases, it may be necessary to discontinue the medication causing the reaction and switch to an alternative therapy.
Pseudolymphoma is a term used to describe a benign reactive lymphoid hyperplasia that mimics the clinical and histopathological features of malignant lymphomas. It is also known as pseudolymphomatous cutis or reactive lymphoid hyperplasia.
Pseudolymphoma can occur in various organs, but it is most commonly found in the skin. It is usually caused by a localized immune response to an antigenic stimulus such as insect bites, tattoos, radiation therapy, or certain medications. The condition presents as a solitary or multiple nodular lesions that may resemble lymphoma both clinically and histologically.
Histologically, pseudolymphoma is characterized by a dense infiltrate of lymphocytes, plasma cells, and other immune cells, which can mimic the appearance of malignant lymphoma. However, unlike malignant lymphomas, pseudolymphomas lack cytological atypia, mitotic activity, and clonal proliferation of lymphoid cells.
Pseudolymphoma is usually a self-limiting condition that resolves spontaneously or with the removal of the antigenic stimulus. However, in some cases, it may persist or recur, requiring further evaluation and treatment to exclude malignant lymphoma.
Acute Generalized Exanthematous Pustulosis (AGEP) is a severe cutaneous adverse reaction that typically occurs within 48 hours after the initiation of medication. It is characterized by the rapid development of widespread sterile pustules on an erythematous and edematous base, often accompanied by systemic symptoms such as fever and neutrophilia.
The most common triggers for AGEP are antibiotics (such as beta-lactams, macrolides, and fluoroquinolones), antifungals, and calcium channel blockers. The diagnosis of AGEP is based on clinical presentation, histopathological findings, and the exclusion of other causes of pustular eruptions.
The management of AGEP includes immediate discontinuation of the offending medication, supportive care, and sometimes systemic corticosteroids. The prognosis is generally good with most patients recovering within 2 weeks, although recurrences may occur upon re-exposure to the causative agent.
An exanthem is a skin eruption or rash that often occurs as a symptom of various diseases, such as infectious illnesses. It can appear in different forms, including maculopapular (consisting of both macules and papules), vesicular (small fluid-filled blisters), petechial (small purple or red spots caused by bleeding under the skin), or erythematous (reddened). The rash can be localized to certain areas of the body or generalized, covering large parts or the entire body. Exanthems are usually accompanied by other symptoms related to the underlying disease, such as fever, cough, or muscle aches.
Trimethoprim-sulfamethoxazole combination is an antibiotic medication used to treat various bacterial infections. It contains two active ingredients: trimethoprim and sulfamethoxazole, which work together to inhibit the growth of bacteria by interfering with their ability to synthesize folic acid, a vital component for their survival.
Trimethoprim is a bacteriostatic agent that inhibits dihydrofolate reductase, an enzyme needed for bacterial growth, while sulfamethoxazole is a bacteriostatic sulfonamide that inhibits the synthesis of tetrahydrofolate by blocking the action of the enzyme bacterial dihydropteroate synthase. The combination of these two agents produces a synergistic effect, increasing the overall antibacterial activity of the medication.
Trimethoprim-sulfamethoxazole is commonly used to treat urinary tract infections, middle ear infections, bronchitis, traveler's diarrhea, and pneumocystis pneumonia (PCP), a severe lung infection that can occur in people with weakened immune systems. It is also used as a prophylactic treatment to prevent PCP in individuals with HIV/AIDS or other conditions that compromise the immune system.
As with any medication, trimethoprim-sulfamethoxazole combination can have side effects and potential risks, including allergic reactions, skin rashes, gastrointestinal symptoms, and blood disorders. It is essential to follow the prescribing physician's instructions carefully and report any adverse reactions promptly.
Vesiculobullous skin diseases are a group of disorders characterized by the formation of blisters (vesicles) and bullae (larger blisters) on the skin. These blisters form when there is a separation between the epidermis (outer layer of the skin) and the dermis (layer beneath the epidermis) due to damage in the area where they join, known as the dermo-epidermal junction.
There are several types of vesiculobullous diseases, each with its own specific causes and symptoms. Some of the most common types include:
1. Pemphigus vulgaris: an autoimmune disorder where the immune system mistakenly attacks proteins that help to hold the skin together, causing blisters to form.
2. Bullous pemphigoid: another autoimmune disorder, but in this case, the immune system attacks a different set of proteins, leading to large blisters and inflammation.
3. Dermatitis herpetiformis: a skin condition associated with celiac disease, where gluten ingestion triggers an immune response that leads to the formation of itchy blisters.
4. Pemphigoid gestationis: a rare autoimmune disorder that occurs during pregnancy and causes blisters on the abdomen and other parts of the body.
5. Epidermolysis bullosa: a group of inherited disorders where there is a fragile skin structure, leading to blistering and wound formation after minor trauma or friction.
Treatment for vesiculobullous diseases depends on the specific diagnosis and may include topical or systemic medications, such as corticosteroids, immunosuppressants, or antibiotics, as well as wound care and prevention of infection.
Skin diseases, also known as dermatological conditions, refer to any medical condition that affects the skin, which is the largest organ of the human body. These diseases can affect the skin's function, appearance, or overall health. They can be caused by various factors, including genetics, infections, allergies, environmental factors, and aging.
Skin diseases can present in many different forms, such as rashes, blisters, sores, discolorations, growths, or changes in texture. Some common examples of skin diseases include acne, eczema, psoriasis, dermatitis, fungal infections, viral infections, bacterial infections, and skin cancer.
The symptoms and severity of skin diseases can vary widely depending on the specific condition and individual factors. Some skin diseases are mild and can be treated with over-the-counter medications or topical creams, while others may require more intensive treatments such as prescription medications, light therapy, or even surgery.
It is important to seek medical attention if you experience any unusual or persistent changes in your skin, as some skin diseases can be serious or indicative of other underlying health conditions. A dermatologist is a medical doctor who specializes in the diagnosis and treatment of skin diseases.
Tartrazine
E-102
International Numbering System for Food Additives
Orange (colour)
Food coloring
Sunset yellow FCF
Zinc deficiency
Nimetazepam
Galliano (liqueur)
Nutritional neuroscience
Saffron
Trichrome staining
Pyrazolone
Criticism of the Food and Drug Administration
Mushy peas
Ingredients of cosmetics
Brilliant blue FCF
Coal tar
Confectionery
Autoimmune disease
Excipient
Feingold diet
Acid dye
Mad cow crisis
Food intolerance
Wheat allergy
Mountain Dew
Frederick Wratten
Lorazepam
List of food additives
Tartrazine - Wikipedia
Tartrazine - International Association of Color Manufacturers
E102 - Tartrazine
E102 - Tartrazine
E102 - Tartrazine - Page 10
Tartrazine Solution - Volu-Sol
Tartrazine/Lemon yellow | ROMA
Tartrazine C16H9N4Na3O9S2 structure - Flashcards | StudyHippo.com
Tartrazine Food Colour Manufacturer, Supplier, Exporter
Ethnic Tribal Metallic Earrings 'Chime Tartrazine' - Funparey
Factory Price Tartrazine CAS 1934-21-0 - Research-Chem-Lab
Tartrazine Color: The Bright and Controversial Yellow Hue - Cali Post
Tartrazine Yellow, C.I. 19140 (Water Soluble) / FD&C - MOMCARES PH
Yellow 5 (Tartrazine) Food Dye: Concerns and Avoiding It - Food Coloring
Fabric Brightener - Fabric Pre-Post Wash Prices, Manufacturers & Suppliers
Removal of Food Dye Tartrazine (E102) from Aqueous Solution using ZnO and CuO-TiO2 as Photocatalysts
Fixed Drug Eruptions: Background, Pathophysiology, Etiology
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JECFA Releases Call for Data for 82nd Meeting
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Surface Behavior of Rhodamin and Tartrazine on Silica-Cellulose Sol-Gel Surfaces by Thin Layer Elution | Wonorahardjo | The...
Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse<...
BBC News | E-CYCLOPEDIA | Chicken tikka masala: Spice and easy does it
DailyMed - HYDROXYZINE PAMOATE capsule
Fotivda 890mcg hard capsules - Summary of Product Characteristics (SmPC) - (emc)
Zatarain's® Cajun Style Smoked Sausage | Zatarain's
McCormick® Gourmet Collection Thyme, Ground (tomillo molido, línea gourmet) | Espanol
Contain tartrazine5
- Many foods contain tartrazine in varying proportions, depending on the manufacturer or person preparing the food. (wikipedia.org)
- A number of personal care and cosmetics products may contain tartrazine, usually labelled as CI 19140 or FD&C Yellow 5, including: Liquid and bar soaps, green hand sanitizer, moisturizers and lotions, mouth washes, perfumes, toothpastes, and shampoos, conditioners and other hair products. (wikipedia.org)
- Types of pharmaceutical products that may contain tartrazine include vitamins, antacids, cold medications (including cough drops and throat lozenges), lotions and prescription drugs. (wikipedia.org)
- Trials could be in either adults or children with asthma or allergic asthma (e.g. sensitivity to aspirin or food items known to contain tartrazine). (cochrane.org)
- This product does not contain tartrazine. (pharmasave.com)
E1021
- When in food, tartrazine is typically labelled as "color", "tartrazine", or "E102", depending on the jurisdiction, and the applicable labeling laws (see Regulation below). (wikipedia.org)
Dyes2
- Tartrazine appears to cause the most allergic and intolerance reactions of all the azo dyes, particularly among asthmatics and those with an aspirin intolerance. (wikipedia.org)
- These dyes include curcumin , anthocyanin , and tartrazine (yellow dye #5). (nih.gov)
Aspirin3
- There has been conflicting evidence as to whether tartrazine causes exacerbations of asthma with some studies finding a positive association especially in individuals with cross-sensitivity to aspirin. (cochrane.org)
- The authors discuss the bronchoconstriction caused by tartrazine (Yellow 5) in people who are aspirin-sensitive, as well as its effect on the prostaglandin system of guinea pig lungs. (talkingaboutthescience.com)
- 4. Before you take this drug, tell your doctor if you are allergic to aspirin or tartrazine. (stason.org)
Carmine1
- Colour Carmine, Tartrazine E104, E133. (notonthehighstreet.com)
Ponceau1
- Each capsule shell/ink contains about 0.6 mg of methyl paraben, 0.15 mg of propyl paraben, 0.015 mg of sunset yellow FCF, 0.165 mg tartrazine and 1.5 mg ponceau 4R. (who.int)
Yellow9
- Tartrazine is a synthetic lemon yellow azo dye primarily used as a food coloring. (wikipedia.org)
- Tartrazine is a commonly used color all over the world, mainly for yellow, and can also be used with brilliant blue FCF (FD&C Blue 1, E133) or green S (E142) to produce various green shades. (wikipedia.org)
- Products containing tartrazine commonly include processed commercial foods that have an artificial yellow or green color, or that consumers expect to be brown or creamy looking. (wikipedia.org)
- Various types of medications include tartrazine to give a yellow, orange or green hue to a liquid, capsule, pill, lotion, or gel, primarily for easy identification. (wikipedia.org)
- This synthetic dye, also known as Tartrazine, is frequently referred to as FD&C Yellow No. 5 in the United States. (culinarysolvent.com)
- Look for Yellow No. 5, Yellow No. 6, Tartrazine, Sunset Yellow FCF, or their respective E numbers in the ingredients list. (culinarysolvent.com)
- This is sad, the transparent tartrazine yellow I put into the tubes bled through the acrylic medium when I painted the first day of a painting today, 5-17-13. (realcolorwheel.com)
- There are also several 'Tartrazine Yellow' products. (realcolorwheel.com)
- contains FD&C yellow no. 5 (tartrazine) as a color additive. (rolaids.com)
Allergic2
- Studies of tartrazine exclusion for other allergic conditions such as hay fever, allergic rhinitis and eczema were only considered if the results for subjects with asthma were separately identified. (cochrane.org)
- Ardern K. Tartrazine exclusion for allergic asthma. (cochrane.org)
Artificial1
- Our study aimed to determine the long-term (30 and 90 days) exposure effect of one of the commonly used artificial food colorants , tartrazine , on NMRI mice . (bvsalud.org)
Ingredients1
- Most, if not all, medication data sheets are required to contain a list of all ingredients, including tartrazine. (wikipedia.org)
Absorbance1
- Tartrazine is water-soluble and has a maximum absorbance in an aqueous solution at 425 nm. (wikipedia.org)
Sensitivity2
- Symptoms from tartrazine sensitivity can occur by either ingestion or cutaneous exposure to a substance containing tartrazine. (wikipedia.org)
- Routine tartrazine exclusion may not benefit most patients, except those very few individuals with proven sensitivity. (cochrane.org)
Food3
- Tartrazine is the best known and one of the most commonly used food additives. (cochrane.org)
- Yup, tartrazine merupakan salah satu food additive atau bahan tambahan pangan (BTP) berjenis pewarna yang diizinkan di Indonesia. (web.id)
- In the picture: tartrazine, labeled as a food coloring. (botanical-online.com)
Allergy1
- The Canadian Compendium of Pharmaceuticals and Specialties (CPS), a prescribing reference book for health professionals, mentions tartrazine as a potential allergy for each drug that contains tartrazine. (wikipedia.org)
Effects3
- There is much controversy about whether tartrazine has ill effects on individuals who are not clearly intolerant. (wikipedia.org)
- Due to the paucity of available evidence, it is not possible to provide firm conclusions as to the effects of tartrazine on asthma control. (cochrane.org)
- Tartrazine alone could elicit effects on the expressions of NFκB (p = 0.013) and MAPK8 (p = 0.022). (nih.gov)
Include1
- Some include tartrazine in the allergens alert section. (wikipedia.org)
Effect2
- To assess the overall effect of tartrazine (exclusion or challenge) in the management of asthma. (cochrane.org)
- Warning: Tartrazine may an have effect on activity and attention in children. (notonthehighstreet.com)
Studies1
- In none of the studies did tartrazine challenge or avoidance in diet significantly alter asthma outcomes. (cochrane.org)
Activity1
- Tartrazine Modifies the Activity of DNMT and HDAC Genes-Is This a Link between Cancer and Neurological Disorders? (bvsalud.org)
People1
- It is not clear how many individuals are sensitive or intolerant to tartrazine, but the University of Guelph estimates that it is 1 to 10 out of every ten thousand people (0.01% to 0.1% of the population). (wikipedia.org)
Analysis1
- Selama ini, beberapa metode sudah digunakan untuk mengukur/mendeteksi kadar zat tartrazine ini, seperti Stopped-flow kinetic analysis , voltammetric analysis , visible spectrophotometry , bahkan High Performance Liquid Chromatography . (web.id)