Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.Skin DiseasesSkin Neoplasms: Tumors or cancer of the SKIN.Skin Physiological Phenomena: The functions of the skin in the human and animal body. It includes the pigmentation of the skin.Skin Tests: Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.Skin Absorption: Uptake of substances through the SKIN.Skin Pigmentation: Coloration of the skin.Skin, Artificial: Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.Skin Diseases, Bacterial: Skin diseases caused by bacteria.Skin UlcerEpidermis: The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).Skin Abnormalities: Congenital structural abnormalities of the skin.Staphylococcal Skin Infections: Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.Dermatitis: Any inflammation of the skin.Dermatologic Surgical Procedures: Operative procedures performed on the SKIN.Skin Diseases, Viral: Skin diseases caused by viruses.Skin Cream: A water-soluble medicinal preparation applied to the skin.Skin Physiological Processes: Biological activities and functions of the SKIN.Mice, Hairless: Mutant strains of mice that produce little or no hair.Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)Ultraviolet Rays: That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.Dermis: A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of causes.Administration, Cutaneous: The application of suitable drug dosage forms to the skin for either local or systemic effects.Administration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Skin Diseases, Parasitic: Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)Keratosis: Any horny growth such as a wart or callus.Wound Healing: Restoration of integrity to traumatized tissue.Sunlight: Irradiation directly from the sun.Sunscreening Agents: Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Hair Follicle: A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.Rats, Hairless: Mutant strains of rats that produce little or no hair. Several different homozygous recessive mutations can cause hairlessness in rats including rnu/rnu (Rowett nude), fz/fz (fuzzy), shn/shn (shorn), and nznu/nznu (New Zealand nude). Note that while NUDE RATS are often hairless, they are most characteristically athymic.9,10-Dimethyl-1,2-benzanthracene: 7,12-Dimethylbenzanthracene. Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.Hair: A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.Blister: Visible accumulations of fluid within or beneath the epidermis.Sunburn: An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.Sebaceous Glands: Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.Skin Manifestations: Dermatologic disorders attendant upon non-dermatologic disease or injury.Langerhans Cells: Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.Water Loss, Insensible: Loss of water by diffusion through the skin and by evaporation from the respiratory tract.Emollients: Oleagenous substances used topically to soothe, soften or protect skin or mucous membranes. They are used also as vehicles for other dermatologic agents.Dermatitis, Allergic Contact: A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.Dermatologic Agents: Drugs used to treat or prevent skin disorders or for the routine care of skin.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Dermatology: A medical specialty concerned with the skin, its structure, functions, diseases, and treatment.Injections, Intradermal: The forcing into the skin of liquid medication, nutrient, or other fluid through a hollow needle, piercing the top skin layer.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Melanocytes: Mammalian pigment cells that produce MELANINS, pigments found mainly in the EPIDERMIS, but also in the eyes and the hair, by a process called melanogenesis. Coloration can be altered by the number of melanocytes or the amount of pigment produced and stored in the organelles called MELANOSOMES. The large non-mammalian melanin-containing cells are called MELANOPHORES.Tuberculin Test: One of several skin tests to determine past or present tuberculosis infection. A purified protein derivative of the tubercle bacilli, called tuberculin, is introduced into the skin by scratch, puncture, or interdermal injection.Dermatitis, Occupational: A recurrent contact dermatitis caused by substances found in the work place.Dermatitis, Irritant: A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)Drug Eruptions: Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. These may assume various morphologic patterns and produce various types of lesions.Surgical Flaps: Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.Intradermal Tests: Skin tests in which the sensitizer is injected.Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)Neoplasms, Radiation-Induced: Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Radiodermatitis: A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation.Dermatomycoses: Superficial infections of the skin or its appendages by any of various fungi.Melanins: Insoluble polymers of TYROSINE derivatives found in and causing darkness in skin (SKIN PIGMENTATION), hair, and feathers providing protection against SUNBURN induced by SUNLIGHT. CAROTENES contribute yellow and red coloration.Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Pigmentation DisordersKeratosis, Actinic: White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Irritants: Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.Soft Tissue Infections: Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)Mice, Inbred C57BLSkin Diseases, Papulosquamous: A group of dermatoses with distinct morphologic features. The primary lesion is most commonly a papule, usually erythematous, with a variable degree of scaling on the surface. Plaques form through the coalescing of primary lesions.Keratins: A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.Body Temperature Regulation: The processes of heating and cooling that an organism uses to control its temperature.Forehead: The part of the face above the eyes.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.Skin Diseases, Vascular: Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area.Scleroderma, Localized: A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.Laser-Doppler Flowmetry: A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.Collagen: A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Mice, Inbred SENCAR: Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to UV radiation tumorigenesis with single high-dose, but not chronic low-dose, exposures. SENCAR (SENsitive to CARcinogenesis) mice are used in research as an animal model for tumor production.Hypersensitivity, Delayed: An increased reactivity to specific antigens mediated not by antibodies but by cells.Dermoscopy: A noninvasive technique that enables direct microscopic examination of the surface and architecture of the SKIN.Immunoglobulin E: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Dermatitis, Exfoliative: The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)Carcinogens: Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.Sweat Glands: Sweat-producing structures that are embedded in the DERMIS. Each gland consists of a single tube, a coiled body, and a superficial duct.Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.Patch Tests: Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.Mice, Inbred BALB CHand DermatosesPermeability: Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.Sebum: The oily substance secreted by SEBACEOUS GLANDS. It is composed of KERATIN, fat, and cellular debris.Skin Lightening Preparations: Substances used to obtain a lighter skin complexion or to treat HYPERPIGMENTATION disorders.Ear, External: The outer part of the hearing system of the body. It includes the shell-like EAR AURICLE which collects sound, and the EXTERNAL EAR CANAL, the TYMPANIC MEMBRANE, and the EXTERNAL EAR CARTILAGES.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Hypersensitivity, Immediate: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.Anura: An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Self-Examination: The inspection of one's own body, usually for signs of disease (e.g., BREAST SELF-EXAMINATION, testicular self-examination).Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Ichthyosis: Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.PUVA Therapy: Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA).Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.Needles: Sharp instruments used for puncturing or suturing.Clothing: Fabric or other material used to cover the body.Dose-Response Relationship, Radiation: The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Iontophoresis: Therapeutic introduction of ions of soluble salts into tissues by means of electric current. In medical literature it is commonly used to indicate the process of increasing the penetration of drugs into surface tissues by the application of electric current. It has nothing to do with ION EXCHANGE; AIR IONIZATION nor PHONOPHORESIS, none of which requires current.Facial DermatosesTetradecanoylphorbol Acetate: A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.Keratolytic Agents: Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.Neoplasms, Adnexal and Skin Appendage: Neoplasms composed of sebaceous or sweat gland tissue or tissue of other skin appendages. The concept does not refer to neoplasms located in the sebaceous or sweat glands or in the other skin appendages.Eczema: A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed).Mechanoreceptors: Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.Hair Color: Color of hair or fur.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Ultraviolet Therapy: The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.Anti-Infective Agents, Local: Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.Nevus: A circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes and therefore presumed to be of hereditary origin.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Protective Clothing: Clothing designed to protect the individual against possible exposure to known hazards.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Nevus, Pigmented: A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi.Alopecia: Absence of hair from areas where it is normally present.Carcinoma, Skin Appendage: A malignant tumor of the skin appendages, which include the hair, nails, sebaceous glands, sweat glands, and the mammary glands. (From Dorland, 27th ed)Touch: Sensation of making physical contact with objects, animate or inanimate. Tactile stimuli are detected by MECHANORECEPTORS in the skin and mucous membranes.Epidermolysis Bullosa: Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.Soaps: Sodium or potassium salts of long chain fatty acids. These detergent substances are obtained by boiling natural oils or fats with caustic alkali. Sodium soaps are harder and are used as topical anti-infectives and vehicles in pills and liniments; potassium soaps are soft, used as vehicles for ointments and also as topical antimicrobials.Hot Temperature: Presence of warmth or heat or a temperature notably higher than an accustomed norm.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Mustard Gas: Severe irritant and vesicant of skin, eyes, and lungs. It may cause blindness and lethal lung edema and was formerly used as a war gas. The substance has been proposed as a cytostatic and for treatment of psoriasis. It has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP-85-002, 1985) (Merck, 11th ed).Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Pemphigus: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.Scleroderma, Diffuse: A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.Sunbathing: Exposing oneself to SUNLIGHT or ULTRAVIOLET RAYS.Dermatitis, Phototoxic: A nonimmunologic, chemically induced type of photosensitivity producing a sometimes vesiculating dermatitis. It results in hyperpigmentation and desquamation of the light-exposed areas of the skin.Physical Stimulation: Act of eliciting a response from a person or organism through physical contact.Mast Cells: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Malassezia: A mitosporic fungal genus that causes a variety of skin disorders. Malassezia furfur (Pityrosporum orbiculare) causes TINEA VERSICOLOR.Keratosis, Seborrheic: Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.Dermatitis, Seborrheic: A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.Cocarcinogenesis: The combination of two or more different factors in the production of cancer.Thermography: Imaging the temperatures in a material, or in the body or an organ. Imaging is based on self-emanating infrared radiation (HEAT WAVES), or on changes in properties of the material or tissue that vary with temperature, such as ELASTICITY; MAGNETIC FIELD; or LUMINESCENCE.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Antisepsis: The destruction of germs causing disease.Amphibian Proteins: Proteins obtained from species in the class of AMPHIBIANS.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Hair Diseases: Diseases affecting the orderly growth and persistence of hair.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Forearm: Part of the arm in humans and primates extending from the ELBOW to the WRIST.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Warts: Benign epidermal proliferations or tumors; some are viral in origin.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Scabies: A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.Clobetasol: A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Cold Temperature: An absence of warmth or heat or a temperature notably below an accustomed norm.Toes: Any one of five terminal digits of the vertebrate FOOT.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Pressure Ulcer: An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.Foot Dermatoses: Skin diseases of the foot, general or unspecified.Urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Keratin-10: A type I keratin that is found associated with the KERATIN-1 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-10 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.Bandages: Material used for wrapping or binding any part of the body.Hand: The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.Feathers: Flat keratinous structures found on the skin surface of birds. Feathers are made partly of a hollow shaft fringed with barbs. They constitute the plumage.Fingers: Four or five slender jointed digits in humans and primates, attached to each HAND.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.Arsenic: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)Croton Oil: Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.Eyelids: Each of the upper and lower folds of SKIN which cover the EYE when closed.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Cellulitis: An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.Granulation Tissue: A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.Intermediate Filament Proteins: Filaments 7-11 nm in diameter found in the cytoplasm of all cells. Many specific proteins belong to this group, e.g., desmin, vimentin, prekeratin, decamin, skeletin, neurofilin, neurofilament protein, and glial fibrillary acid protein.Gloves, Protective: Coverings for the hands, usually with separations for the fingers, made of various materials, for protection against infections, toxic substances, extremes of hot and cold, radiations, water immersion, etc. The gloves may be worn by patients, care givers, housewives, laboratory and industrial workers, police, etc.Nails: The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Staphylococcus aureus: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.Melanosis: Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
  • Using an eye treatment or eye cream on a daily basis can help to hydrate and protect the fragile skin around the eyes. (walgreens.com)
  • The present invention relates to a method for treating spots and other symptoms of acne and related skins disorders in mammals, which comprises applying to the affected area of the skin of the mammal a non-aqueous composition comprising a dermatologically effective amount of a particulate silica, silica hydrate or precursor thereof. (google.com)
  • The invention also provides compositions for topical application to the skin which comprise particulate silica, silica hydrate or a precursor thereof in a non-aquous carrier medium. (google.com)
  • Doing so will help to hydrate the skin from the inside. (bellaonline.com)
  • And boy, does it ever hydrate the skin! (goodhousekeeping.com)
  • Hydrate and nourish your skin with a custom facial from this spa. (groupon.com)
  • The water-activated exfoliant is packed with skin-rejuvenating ingredients like Japanese rice bran, rice and papaya enzymes and crushed pearl extract that gently remove impurities, hydrate skin and restore youthful radiance. (forbes.com)
  • The star ingredient is packed with over 50 micronutrients that firm and hydrate skin, clear complexion, boost skin cell renewal and minimize appearance of dark spots and fine lines. (forbes.com)
  • Gina Pieper, artistic director for Empire Beauty Schools says, "If your skin gets dry like mine does in winter, I recommend having an exfoliator and moisturizer, I love Dermalogica Skin Prep Scrub and the Intensive Moisture Balance. (sheknows.com)
  • Ultrasensitive skin might not be right for this skin scrub with micro-polishing beads, but if you have oilier skin that can handle the extra scrubbing action, this one is a really good bet for getting rid of acne and blackheads. (nymag.com)
  • This ensures the thorough removal of make-up and oils quickly and easily, avoiding the need to roughly scrub your skin. (panasonic.com)
  • Use glycolic pads (see "The Line Eraser" Minibar ) or a very gentle scrub every other day to keep things clear, avoiding abrasive scrubs that can irritate skin and exacerbate acne outbreaks. (marieclaire.com)
  • Learn about topics such as How to Use a Pumice Stone , How to Use Sugar Scrub , How to Get Rid of Dry Skin on Feet , and more with our helpful step-by-step instructions with photos and videos. (wikihow.com)
  • Don't scrub your skin -- it will only lead to more oil production and breakouts. (medicinenet.com)
  • A stimulating blend of shea butter,exfoliating brown sugar,and essential oils refines and brightens the skin in this gentle scrub from Bamford,crafted in England and scented with rich,spicy notes of cinnamon and rosemary. (shopstyle.com)
  • Vitamin A is essential for skin cell development, and getting adequate amounts in the diet can maintain strong, supple skin. (medicinenet.com)
  • Polishes skin's surface to reduce the look of imperfections, improve tone and texture and reveal soft, supple, healthy-looking skin. (neimanmarcus.com)
  • After using clean the skin with skin toner (not included), skin will feel refreshed,clean,tender and supple. (ebay.co.uk)
  • Fear not dry-skin kin, there are a few things you can do to ensure that your skin remains soft, supple and moisturised both from the outside and from within, during this rather unforgiving season. (dawn.com)
  • Why top quality ingredients are essential in natural skin care - Duration: 72 seconds. (youtube.com)
  • Take years off your skin with all natural plant based ingredients - Duration: 90 seconds. (youtube.com)
  • This article is about natural ingredients and traditional medicine in skin care. (wikipedia.org)
  • Clinical and laboratory studies have identified activities in many natural ingredients that have potential beneficial activities for the skin. (wikipedia.org)
  • The more ingredients in a product, the more likely it will irritate your skin. (webmd.com)
  • Using sunscreen every day can help, but many ingredients in it can irritate the skin. (webmd.com)
  • The most beneficial and effective sunblock ingredients are zinc oxide and titanium dioxide, mineral salts that scatter sunrays and reflect them away from vulnerable skin. (selfgrowth.com)
  • Ingredients such as retinol (a form of vitamin A), vitamin C and advanced peptides can stimulate collagen production, strengthening and protecting the delicate skin around the eyes. (walgreens.com)
  • Advanced skin care ingredients, such as neuropeptides, penetrate the skin and encourage fluids to disperse. (walgreens.com)
  • Ingredients, such as caffeine, can help to tighten the skin, reducing under-eye bags. (walgreens.com)
  • When companies develop skin care ranges, they often include active ingredients that have a cumulative effect across this basic regime. (walgreens.com)
  • It's always tough to find one that doesn't leave a ghostly white cast on your face, but this one goes on smooth and slightly tinted, plus contains skin-protecting ingredients, so it might be worth splurging a little more for sunscreen. (nymag.com)
  • skin care 411: the importance of these ingredients in preventing premature aging of the skin! (scoop.it)
  • This was the inspiration for our new skin care collection, Mary Kay Naturally ™ , where naturally derived ingredients meet exciting product forms. (marykay.com)
  • We want you to feel confident in our skin-loving ingredients, so every Mary Kay Naturally ™ product is third-party certified as natural according to comprehensive standards. (marykay.com)
  • Avoid mechanical exfoliants (things like scrubs and washcloths that physically remove dead skin cells) and chemical exfoliants (ingredients like acids that dissolve or break up dead skin cells). (marieclaire.com)
  • In a day when skin care has become so complicated one might need a PhD to understand what various salves and sprays are supposed to do (let alone decipher the ingredients list), Ms. Healy's simple yet elegant approach is refreshing. (treehugger.com)
  • 79% organic ingredients -Instructions for use: - Using the pipette, add one to two drops directly onto the skin - Alternatively, add a few drops to boost another skincare product - Use in the evening as often as desired before moisturizing - 15ml/ 0.5fl.oz. (shopstyle.com)
  • Supercharged with ingredients like black rose, Vitamin E, geranium oil and shea butter, the rose-scented mask plumps, brightens and deeply hydrates the skin in under 20 minutes. (forbes.com)
  • Harness the power of plant-based active ingredients with our edit of nourishing, purifying and anti-ageing must-haves from Sisley Skincare. (harrods.com)
  • A vibrating silicone face brush is great for stimulating blood flow, which results in tighter, healthier looking skin. (cvs.com)
  • Get younger, healthier looking skin. (drugs.com)
  • Dead skin cells are polished away with the help of Alumina (Aluminum Oxide), the same key ingredient used by dermatologists to dramatically improve skin's texture. (marykay.com)
  • As your skin absorbs the very fine steam particles, your skin's layers are gently and naturally stimulated. (panasonic.com)
  • According to Evan Healy, aesthetician and creator of the evanhealy skin care line, when we bombard our skin with chemicals that dissolve the epidermal layer we damage the skin's ability to defend itself. (treehugger.com)
  • Topical retinoids have the effect of normalizing the skin's follicles and can be very effective in taking care of acne. (buzzle.com)
  • Dehydrated, rough and dull skin is often the result, as a combination of sun, smoke, dirt and grime can quickly weaken your skin's complexion barrier - obviously something we want to avoid! (nuskin.com)
  • A barrier repair cream, such as one that contains ceramides, can help restore the skin," Martin says. (webmd.com)
  • If you have dry, flaky, or itchy skin, you might use a cream or ointment. (kidshealth.org)
  • Night can be a good time to add in a thicker cream (make sure it's still easily absorbed so it doesn't smear on your pillow) with extra skin-saving properties. (aarp.org)
  • Vanicream™ Skin Cream is a non-greasy, long-lasting moisturizing cream that is easy-to-spread, quickly absorbed and non-comedogenic (does not cause acne). (ohsu.edu)
  • If your skin is sensitive and dry, go with a soothing, ceramide-rich cream to strengthen the protective barrier. (marieclaire.com)
  • But a little cream or oil can go a long way when getting camera ready or maintaining healthy skin. (hollywoodreporter.com)
  • a face cream with added UV protection to keep your skin moisturised each day, and another for the night time. (nuskin.com)
  • KORRES WILD ROSE Kpema CC Colour Correcting Cream SPF30 - 30ml MEDIUM SHADE Moisturising cream that instantly brightens, evens out skin tone, covers imperfections and offers sunscreen protection. (ebay.co.uk)
  • Using milk cream as a face pack also helps to nourish and moisturise your skin. (dawn.com)
  • You take care of skin by using moisturized cream and less use of chemical soap, cream. (drugs.com)
  • Prevent your skin from direct sun damages and also wash your skin atleast two times with effective skin cream.eat a healthy diet and drink plenty of water. (drugs.com)
  • Although nothing can substitute for a good diet and regular exercise, this cream will do its part to keep your skin looking toned. (trendhunter.com)
  • According to the American Academy of Dermatology, skin cancer is the most prevalent of all cancers and, with more than 900,000 cases reported each year, rivals its reputation as the "undeclared epidemic. (selfgrowth.com)
  • Whether you drink it or apply it to the skin, a 2000 study in the Archives of Dermatology showed green tea might help reduce the risk of damage from UV rays from the sun, which may reduce the risk for skin cancer. (medicinenet.com)
  • Skin care differs from dermatology, as traditionally practiced, by its additional but less medical scope and by its inclusion of non-physician professionals, such as estheticians and wound care nursing staff. (wikipedia.org)
  • Nevertheless, dermatology has co-opted some aspects of skin care, particularly in the U.S., and to a significantly lesser extent elsewhere, such as the U.K. Add from Guidelines for neonatal skin care have been developed. (wikipedia.org)
  • Even if your skin is naturally dark, you still need to use a sunscreen. (kidshealth.org)
  • Because sunscreen cannot protect your skin completely from the sun, it's also a good idea to wear a brimmed hat and use a lip balm containing sunscreen. (kidshealth.org)
  • Zinc sunscreen blocks the widest spectrum of UVA and UVB rays, protecting skin against burning and the premature appearance of aging and risk of skin cancer. (ohsu.edu)
  • This is a color-infused sunscreen that provides a self-adjusting tint for all skin types. (ohsu.edu)
  • A mineral make up with broad-spectrum sunscreen that is ideal for people with medium or olive, sensitive skin. (ohsu.edu)
  • To protect skin from the sun's UVA and UVB rays and to keep dullness and tanning at bay, wearing a sunscreen is a must. (indiatimes.com)
  • Sunscreen should be applied to all areas of the skin that will be exposed to sunlight, and at least a tablespoon (25 ml) should be applied to each limb, the face, chest, and back, to ensure thorough coverage. (wikipedia.org)
  • From tinted formulas that give gorgeous glow to those with unreal skin-care benefits on the side, the newest and greatest sunscreens are major multitaskers. (refinery29.com)
  • Looking for glowing skin? (amazon.com)
  • Want clearer, more glowing skin in time for your wedding? (theknot.com)
  • Here's your guide to getting a beautiful and glowing skin. (buzzle.com)
  • This article gives you simple methods on how to prepare salt scrubs at home, for a younger and glowing skin. (buzzle.com)
  • Visit our summer body care page for three steps to glowing skin and some summer skincare essentials. (wholefoodsmarket.com)
  • Keep reading to learn the recipe to gorgeous, glowing skin straight from her mouth. (popsugar.com)
  • And, in the quest for dewy, fresh and glowing skin, you could end up making a few skin care mistakes. (indiatimes.com)
  • For natural glowing skin Clean the face 2 times a day along with hot water and a soap designed for people with pimples. (drugs.com)
  • The formulas are specifically designed to improve skin texture and reduce the look of fine lines, and the study showed their effectiveness: Participants saw visible results immediately, and younger and more radiant-looking skin after four weeks of use. (theknot.com)
  • Regular application of vitamin E oil on skin can bring about marked improvement in texture of the skin. (buzzle.com)
  • And, just out, the Algae Brightening Mask promises to reduce fine lines, improve texture, and absorb excess sebum and impurities for a smoother and more radiant skin. (vanityfair.com)
  • Talking about the amazing benefits of coffee for your skin and why I formulated my Texture Reform to include Coffea Arabica Fruit Extract in today's Skin Tip! (hollywoodreporter.com)
  • Texture: Light and watery, this toning lotion penetrates into the skin surface. (neimanmarcus.com)
  • After washing your face , no matter your skin type -- dry, oily or sensitive -- you need moisture to help improve skin tone and texture, and cover up imperfections. (go.com)
  • Due to these factors, fine lines can start to develop, skin tone can turn dull and skin can begin to obtain a rough texture. (go.com)
  • This tool is dermatologist recommended and clinically proven to enhance overall skin color, texture and tone. (shopstyle.com)
  • Apple, Lemon and Red Grape Extracts accelerate natural cell renewal and promotes a brighter complexion - English clay controls sebum production to balance skin - Softening Lactic Acid improves skin tone and texture -Instructions for use: - Apply a generous layer onto cleansed face, neck and décolletage - Leave for 8-10 minutes before rinsing with warm water - Use once a week - 45ml/ 1.5fl.oz. (shopstyle.com)
  • A toll-free phone line supervised by certified wound care nurses and supported by a network of advanced wound care product specialists. (medline.com)
  • How to have youthful looking skin at any age - Duration: 76 seconds. (youtube.com)
  • When you browse the Walgreens website, you will find kits that address the issues faced by all types of skin: from dry to oily, youthful to mature. (walgreens.com)
  • Since scaling the Billboard Hot 100 chart with summer hit " Despacito ," and amassing several hit singles over a multi-decade career, most people think "music" when they think of Daddy Yankee, but his youthful glow at 40 make others think, "great skin. (people.com)
  • Stem cells, and most commonly platelet rich plasma (PRP), are injected and/or infused into the dermal layers to increase collagen and elastin production and rejuvenate skin for a more youthful, healthy look. (askmen.com)
  • Ideal for dark spots and brightening to reveal youthful and healthy - looking skin! (shopstyle.com)
  • All of our facials are customized to work with the body's physiological systems to promote a gentle detoxification, a release of facial tension and stress, and bring harmony back to the skin, body, and mind. (google.com)
  • Ultrasound is gentle and safe while facilitating the rejuvenation of your skin appearance when used with an effective product on a regular basis. (angelfire.com)
  • From hydration to exfoliation, each Mary Kay Naturally ™ product leaves skin looking healthy with gentle formulas suitable for sensitive skin. (marykay.com)
  • Its ultra-gentle formula respects the skin and may be used 3 to 4 times a week. (neimanmarcus.com)
  • Lime Pearl Extract: Natural source of AHA for gentle skin retexturization, allowing the vitamin C to sink in. (neimanmarcus.com)
  • Even out your complexion with a product that shelters your skin. (womansday.com)
  • Watercress Leaf: A surprising new source, watercress leaf extract brightens complexion, increases radiance and corrects skin tone to diminish the appearance of imperfections. (neimanmarcus.com)
  • It is rich yet never greasy, providing hydration and antioxidant protection to the skin for a visibly younger, softer, and healthier-looking complexion. (neimanmarcus.com)
  • Enriched with carob tree extract that soothes the complexion and Wild Rose, rich in vitamin C, that offers signi cant ability to smooth ne lines and skin discolorations. (ebay.co.uk)
  • You can also keep your skin moisturised by using natural honey as a face or body wash as it will nourish your skin and clean it without leaving it dry. (dawn.com)
  • One reason for the increase in the skin cancer rate is the fact that the ozone layer of the earth's atmosphere is steadily deteriorating, allowing more of the sun's ultraviolet rays (UVs) to reach the planet surface - specifically, UVA, UVB and UVC rays. (selfgrowth.com)
  • We all know we need to protect our skin from the sun's harmful rays. (kidshealth.org)
  • Ultraviolet (UVA and UVB) radiation in the sun's rays can cause sunburn in varying degrees, early ageing and increased risk of skin cancer. (wikipedia.org)
  • their SPF number indicates their effectiveness in protecting the skin from the sun's radiation. (wikipedia.org)
  • There isn't a one-size fits all option when it comes to men's skin care. (aarp.org)
  • Dermatologist S. Manjula Jegasothy, M.D. of Miami Skin Institute weighs in on the future of men's skincare from the aesthetic perspective: "The younger generation of men are definitely more concerned about their skin. (askmen.com)
  • Decide which one is right for you, and put an end to dull skin. (marykay.com)
  • When we're dehydrated our skin becomes dry and dull," Chwalek says. (theknot.com)
  • A dull blade will cause you to place more pressure on your skin and will also cause you to go over the same area multiple times since it won't cut the hair cleanly. (healthcentral.com)
  • People with rosacea may also have sensitive skin on other parts of the body. (webmd.com)
  • Zinc is safe for even the most sensitive skin types. (ohsu.edu)
  • Learn everything you want about Sensitive Skin Care with the wikiHow Sensitive Skin Care Category. (wikihow.com)
  • Learn about topics such as How to Wash Your Face when You Have a Sensitive Skin , How to Care for Sensitive Skin , How to Apply Eyeliner to Sensitive Eyes , and more with our helpful step-by-step instructions with photos and videos. (wikihow.com)
  • Works well for sensitive skin. (neimanmarcus.com)
  • CLICK HERE for more tips for sensitive skin. (go.com)
  • Plant extracts in Simplicite natural skin care - Duration: 72 seconds. (youtube.com)
  • Why we love natural skincare - Duration: 76 seconds. (youtube.com)
  • [ 6 ] Moreover, as part of the natural aging process endogenous defense mechanisms decrease, while the production of reactive oxygen species increases, resulting in accelerated skin aging. (medscape.com)
  • Detergent-based soaps strip natural oils and leave a film on your skin. (aarp.org)
  • If you stay up late night after night to edit your vows or redo your seating chart, you'll not only miss out on this natural glow-getting process, you'll likely have a surge in stress hormones that can lead to unwanted skin concerns like acne. (theknot.com)
  • This is gaining popularity with clients who want a more natural and long-lasting solution to their skin care issues. (askmen.com)
  • In this week's episode of Your Best Life, Karl interviews Adina Grigore, who is the founder of the all-natural, sustainable skincare line SW Basics. (wellness.com)
  • Natural plant extracts (Lemon) along with essential oils (Exotic Verbena and Lavender) invigorate the skin and create a sensation of comfort and freshness. (neimanmarcus.com)
  • The growth of Natural and Organic Skin care and Hair care market has been significantly outpacing the synthetic market consistently for the past many years. (prweb.com)
  • Having said that, hydration doesn't work the other way around - showers and long baths serve to dehydrate you further and rob your skin of its natural oil. (dawn.com)
  • It's an ultra-potent glycolic clay mask that quickly eliminates breakouts by absorbing excess oil, killing bacteria and pulling impurities out of the skin. (sheknows.com)
  • Founder of Arithmetic Skincare in San Francisco, California, Andy Bosselman is really excited about the new focus on this scientific treasure: "A lot of skin conditions are treated by wiping out bacteria indiscriminately. (askmen.com)
  • We'll treat many skin conditions by adding bacteria. (askmen.com)
  • The idea is to restore a balance, so that the good bacteria that's on your skin can better control the problematic bacteria. (askmen.com)
  • It also contains mandelic acid, azelaic acid, salicylic acid, zinc, and our trademarked vassoclear, which penetrates deeply into the dermis to heal and repair skin," she says. (sheknows.com)
  • Nano-ionic technology generates steam particles that are 18,000 times finer than regular steam particles, and are better at deeply penetrating the skin. (panasonic.com)
  • Perfect for parched, dry skin, Bamford's deeply hydrating facial oil is blended with antioxidant-rich Strawberry Seed Oil and omega-rich fatty acids. (shopstyle.com)