Devices for accelerating protons or electrons in closed orbits where the accelerating voltage and magnetic field strength varies (the accelerating voltage is held constant for electrons) in order to keep the orbit radius constant.
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Penetrating electromagnetic radiation emitted when the inner orbital electrons of an atom are excited and release radiant energy. X-ray wavelengths range from 1 pm to 10 nm. Hard X-rays are the higher energy, shorter wavelength X-rays. Soft x-rays or Grenz rays are less energetic and longer in wavelength. The short wavelength end of the X-ray spectrum overlaps the GAMMA RAYS wavelength range. The distinction between gamma rays and X-rays is based on their radiation source.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Devices which accelerate electrically charged atomic or subatomic particles, such as electrons, protons or ions, to high velocities so they have high kinetic energy.
The spectrometric analysis of fluorescent X-RAYS, i.e. X-rays emitted after bombarding matter with high energy particles such as PROTONS; ELECTRONS; or higher energy X-rays. Identification of ELEMENTS by this technique is based on the specific type of X-rays that are emitted which are characteristic of the specific elements in the material being analyzed. The characteristic X-rays are distinguished and/or quantified by either wavelength dispersive or energy dispersive methods.
The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Medical treatment involving the use of controlled amounts of X-Rays.
The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Scattering of a beam of electromagnetic or acoustic RADIATION, or particles, at small angles by particles or cavities whose dimensions are many times as large as the wavelength of the radiation or the de Broglie wavelength of the scattered particles. Also know as low angle scattering. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Small angle scattering (SAS) techniques, small angle neutron (SANS), X-ray (SAXS), and light (SALS, or just LS) scattering, are used to characterize objects on a nanoscale.
Analytical technique for studying substances present at enzyme concentrations in single cells, in situ, by measuring light absorption. Light from a tungsten strip lamp or xenon arc dispersed by a grating monochromator illuminates the optical system of a microscope. The absorbance of light is measured (in nanometers) by comparing the difference between the image of the sample and a reference image.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
Analysis of the energy absorbed across a spectrum of x-ray energies/wavelengths to determine the chemical structure and electronic states of the absorbing medium.
Tomography using x-ray transmission.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
Diagnostic aid in pancreas function determination.
Irradiation of one half or both halves of the body in the treatment of disseminated cancer or widespread metastases. It is used to treat diffuse metastases in one session as opposed to multiple fields over an extended period. The more frequent treatment modalities are upper hemibody irradiation (UHBI) or lower hemibody irradiation (LHBI). Less common is mid-body irradiation (MBI). In the treatment of both halves of the body sequentially, hemibody irradiation permits radiotherapy of the whole body with larger doses of radiation than could be accomplished with WHOLE-BODY IRRADIATION. It is sometimes called "systemic" hemibody irradiation with reference to its use in widespread cancer or metastases. (P. Rubin et al. Cancer, Vol 55, p2210, 1985)
Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
Acidic water usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water.
Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
Any combustible hydrocarbon deposit formed from the remains of prehistoric organisms. Examples are petroleum, coal, and natural gas.
An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.
Stable elementary particles having the smallest known negative charge, present in all elements; also called negatrons. Positively charged electrons are called positrons. The numbers, energies and arrangement of electrons around atomic nuclei determine the chemical identities of elements. Beams of electrons are called CATHODE RAYS.
A contagious disease caused by canine adenovirus (ADENOVIRUSES, CANINE) infecting the LIVER, the EYE, the KIDNEY, and other organs in dogs, other canids, and bears. Symptoms include FEVER; EDEMA; VOMITING; and DIARRHEA.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.
A province of eastern Canada. Its capital is Quebec. The region belonged to France from 1627 to 1763 when it was lost to the British. The name is from the Algonquian quilibek meaning the place where waters narrow, referring to the gradually narrowing channel of the St. Lawrence or to the narrows of the river at Cape Diamond. (From Webster's New Geographical Dictionary, 1988, p993 & Room, Brewer's Dictionary of Names, 1992, p440)
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
The fraudulent misrepresentation of the diagnosis and treatment of disease.
Facilities or services which are especially devoted to providing palliative and supportive care to the patient with a terminal illness and to the patient's family.
A former branch of knowledge embracing the study, description, and classification of natural objects (as animals, plants, and minerals) and thus including the modern sciences of zoology, botany, and mineralogy insofar as they existed at that time. In the 17th, 18th, and 19th centuries it was much used for the generalized pursuit of certain areas of science. (Webster, 3d ed; from Dr. James H. Cassedy, NLM History of Medicine Division)
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.

Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy. (1/504)

Iron is found in high concentration in some areas of the brain, and increased iron in the substantia nigra is a feature of Parkinson's disease. The purpose of this study was to investigate the physical environment of brain iron in post-mortem tissue to provide information on the possible role of iron in neurodegeneration in Parkinson's disease. Iron has also been implicated as the cause of signal loss in areas of high brain iron on T2-weighted MRI sequences. Knowledge of the physical environment of the brain iron is essential in interpreting the cause of signal change. Post-mortem tissue was obtained from six cases of Parkinson's disease and from six age-matched controls. Iron levels were measured using absorption spectrophotometry. Extended X-ray absorption fine structure was used to evaluate the atomic environment of iron within the substantia nigra and both segments of the globus pallidus. Cryo-electron transmission microscopy was used to probe the iron storage proteins in these areas. Iron levels were increased in the parkinsonian nigra and lateral portion of the globus pallidus. Spectra from the extended X-ray absorption fine structure experiments showed that ferritin was the only storage protein detectable in both control and parkinsonian tissue in all areas studied. Cryo-electron transmission microscopy studies showed that ferritin was more heavily loaded with iron in Parkinson's disease when compared with age-matched controls. In summary we have shown that iron levels are increased in two areas of the brain in Parkinson's disease including the substantia nigra, the site of maximal neurodegeneration. This produces increased loading of ferritin, which is the normal brain iron storage protein. It is possible that increased loading of ferritin may increase the risk of free radical-induced damage. Differences in ferritin loading may explain regional differences in iron's effect on the T2 signal.  (+info)

Branching patterns of intramural coronary vessels determined by microangiography using synchrotron radiation. (2/504)

The intramural coronary artery (IMCA) with a diameter of 50-500 micrometers is critical for blood supply to the inner layers of heart muscle. We introduced digital measurement to microangiography using monochromatic synchrotron radiation and quantified branching patterns of the IMCA, the epicardial coronary artery (EPCA), and the distal ileal artery (DIA). The pre- and postbranching diameters were measured (95-1,275 micrometers) in seven dogs. A typical arterial segment divided into two nearly equivalent branches, and a regression line of daughter-to-mother diameter plots was almost identical among the EPCA (y = 0.838x - 16.7 in micrometers), IMCA (y = 0.737x - 2.18), and DIA (y = 0.755x + 8.63). However, a considerable difference was present at a segment where a proximal IMCA branched off from an EPCA (y = 0.182x + 90.2). Moreover, a proximal IMCA diameter had no relationship to the branching order from an EPCA. The precision of this method was confirmed by the good correlation of diameter measurements between two independent observers (r = 0.999, y = 1.02x - 1.07). In conclusion, using digital microangiography we demonstrated that the self-similar branching pattern of coronary arteries was discrete at the connection between the IMCA and EPCA.  (+info)

Digitized cerebral synchrotron radiation angiography: quantitative evaluation of the canine circle of Willis and its large and small branches. (3/504)

BACKGROUND AND PURPOSE: Conventional X-ray angiography lacks the sensitivity and spatial resolution needed to detect small amounts of iodinated contrast material and to quantitate diameters of the small vessels in the brain. The purpose of this study was to ascertain whether digitized synchrotron radiation microangiography, with the use of a high-definition TV camera system, can accurately show small cerebral vessels. METHODS: Six anesthetized dogs were exposed to monochromatic synchrotron radiation with an energy level of 33.3 keV optimized for iodine detection while iodinated contrast material was injected into the brachiocephalic and vertebral arteries. The images were detected with a high-definition TV camera system with a spatial resolution of 30 microm. In all, 26 cerebral angiograms of the circle of Willis with its branches were obtained, and the images were digitized at a workstation. RESULTS: The small branches of the circle of Willis were clearly visible on all images. Vasodilatation of the circle of Willis and its large and small branches induced by CO2 inhalation was quantitatively confirmed on the images: for example, the diameter of one small branch was increased from 0.24 +/- 0.04 mm to 0.38 +/- 0.12 mm. Temporal subtraction improved the image quality. CONCLUSION: The synchrotron radiation angiographic system is useful for visualizing large and small vessels deep in the brain as well as for quantitating their diameters.  (+info)

Yeast RNA polymerase II at 5 A resolution. (4/504)

Appropriate treatment of X-ray diffraction from an unoriented 18-heavy atom cluster derivative of a yeast RNA polymerase II crystal gave significant phase information to 5 A resolution. The validity of the phases was shown by close similarity of a 6 A electron density map to a 16 A molecular envelope of the polymerase from electron crystallography. Comparison of the 6 A X-ray map with results of electron crystallography of a paused transcription elongation complex suggests functional roles for two mobile protein domains: the tip of a flexible arm forms a downstream DNA clamp; and a hinged domain may serve as an RNA clamp, enclosing the transcript from about 8-18 residues upstream of the 3'-end in a tunnel.  (+info)

Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures. (5/504)

The unusual bacteriophage PRD1 features a membrane beneath its icosahedral protein coat. The crystal structure of the major coat protein, P3, at 1.85 A resolution reveals a molecule with three interlocking subunits, each with two eight-stranded viral jelly rolls normal to the viral capsid, and putative membrane-interacting regions. Surprisingly, the P3 molecule closely resembles hexon, the equivalent protein in human adenovirus. Both viruses also have similar overall architecture, with identical capsid lattices and attachment proteins at their vertices. Although these two dsDNA viruses infect hosts from very different kingdoms, their striking similarities, from major coat protein through capsid architecture, strongly suggest their evolutionary relationship.  (+info)

Intramyocardial vascular volume distribution studied by synchrotron radiation-excited X-ray fluorescence. (6/504)

We evaluated the vascular volume distribution with fine resolution (0.1-1.3 mg myocardial tissue) in the sagittal plane of the left ventricle by using the microsphere filling method in 21 dogs. The coronary arterial volume density in the sagittal plane did not exhibit normal distribution and was characterized by variability among the outer-to-inner layers and within the layers (+2SD/-2SD > 80 times), and the median values in the layers ranged from 4.7 to 22. 9 nl/mg myocardial tissue. The fractal analysis of vascular volume revealed a self-similar nature with a fractal dimension (D value) similar to that of flow distribution (1.20 +/- 0.05 and 1.24 +/- 0. 09 for vascular volume and flow distribution, respectively) and had a more marked variability than the flow. The correlation of the regional vascular volume between adjacent regions decreased as the distance increased. However, the correlation coefficients in the endocardial-to-epicardial direction were significantly higher than those in the anterior-to-posterior direction (P < 0.05 by paired t-test). In conclusion, we determined intramyocardial vascular volume density in the sagittal plane, and the distribution revealed considerable variability, self-similarity, and asymmetry in the correlation among the adjacent regions. These observations could be related to the characteristics of the intramural coronary vascular network.  (+info)

Crystal versus solution structures of thiamine diphosphate-dependent enzymes. (7/504)

The quaternary structures of the thiamine diphosphate-dependent enzymes transketolase (EC 2.2.1.1; from Saccharomyces cerevisiae), pyruvate oxidase (EC 1.2.3.3; from Lactobacillus plantarum), and pyruvate decarboxylase (EC 4.1.1.1; from Zymomonas mobilis and brewers' yeast, the latter in the native and pyruvamide-activated forms) were examined by synchrotron x-ray solution scattering. The experimental scattering data were compared with the curves calculated from the crystallographic models of these multisubunit enzymes. For all enzymes noted above, except the very compact pyruvate decarboxylase from Z. mobilis, there were significant differences between the experimental and calculated profiles. The changes in relative positions of the subunits in solution were determined by rigid body refinement. For pyruvate oxidase and transketolase, which have tight intersubunit contacts in the crystal, relatively small modifications of the quaternary structure (root mean square displacements of 0.23 and 0.27 nm, respectively) sufficed to fit the experimental data. For the enzymes with looser contacts (the native and activated forms of yeast pyruvate decarboxylase), large modifications of the crystallographic models (root mean square displacements of 0.58 and 1.53 nm, respectively) were required. A clear correlation was observed between the magnitude of the distortions induced by the crystal environment and the interfacial area between subunits.  (+info)

Specific chemical and structural damage to proteins produced by synchrotron radiation. (8/504)

Radiation damage is an inherent problem in x-ray crystallography. It usually is presumed to be nonspecific and manifested as a gradual decay in the overall quality of data obtained for a given crystal as data collection proceeds. Based on third-generation synchrotron x-ray data, collected at cryogenic temperatures, we show for the enzymes Torpedo californica acetylcholinesterase and hen egg white lysozyme that synchrotron radiation also can cause highly specific damage. Disulfide bridges break, and carboxyl groups of acidic residues lose their definition. Highly exposed carboxyls, and those in the active site of both enzymes, appear particularly susceptible. The catalytic triad residue, His-440, in acetylcholinesterase, also appears to be much more sensitive to radiation damage than other histidine residues. Our findings have direct practical implications for routine x-ray data collection at high-energy synchrotron sources. Furthermore, they provide a direct approach for studying the radiation chemistry of proteins and nucleic acids at a detailed, structural level and also may yield information concerning putative "weak links" in a given biological macromolecule, which may be of structural and functional significance.  (+info)

New advances in instrumentation, demonstration of proof-of-principle studies, and development of new tools and methods for data analysis and interpretation have enabled the technique of Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy to become a useful tool for structural and functional biology. This paper discusses the characterisation of two new SRCD beamlines, CD1 at the Institute for Storage Rings (ISA), Denmark and 4B8 at the Beijing Synchrotron Radiation Facility (BSRF), China, and new applications of the method for examining biological systems ...
article{9c427bbf-e48d-404f-aa8d-386a5072b5fd, abstract = {,p,Apolipoprotein A-I (apoA-I) in high-density lipoprotein (HDL) provides cardiovascular protection. Synchrotron radiation circular dichroism (SRCD) spectroscopy was used to analyze the dynamic solution structure of the apoA-I protein in the apo- and HDL-states and the protein structure conversion in HDL formation. Wild-type apoA-I protein was compared to human variants that either are protective (R173C, Milano) or lead to increased risk for ischaemic heart disease (A164S). Comparable secondary structure distributions in the HDL particles, including significant levels of beta strand/turn, were observed. ApoA-I Milano in HDL displayed larger size heterogeneity, increased protein flexibility, and an altered lipid-binding profile, whereas the apoA-I A164S in HDL showed decrease thermal stability, potentially linking the intrinsic HDL propensities of the variants to disease risk.,/p,}, articleno = {13540}, author = {Giudice, Rita Del and ...
X-ray computed tomography (CT) experiments performed at synchrotron radiation facilities require adequate computing and storage resources due to the large amount of acquired and reconstructed data produced. To satisfy the heterogeneous needs of beamline users, flexible solutions are also required. Moreover, the growing demand of quantitative image analysis impose an easy integration between the CT reconstruction process and the subsequent feature extraction step. This paper presents some of the software solutions adopted by the SYRMEP beamline of the Italian synchrotron radiation facility Elettra. By using the enhanced version of the reconstruction software here presented as well as data reduction and data analysis tools, beamline users can easily implement an integrated and comprehensive approach to the digital image processing and image analysis required by a tomography-oriented scientific workflow.. ...
Synchrotron radiation X-ray tomographic microscopy (SRXTM) was used to characterize the three-dimensional microstructure, geometry and distribution of different phases in two shale samples obtained from the North Sea (sample N1) and the Upper Barnett Formation in Texas (sample B1). Shale is a challenging material because of its multiphase composition, small grain size, low but significant amount of porosity, as well as strong shape- and lattice-preferred orientation. The goals of this round-robin project were to (i) characterize microstructures and porosity on the micrometer scale, (ii) compare results measured at three synchrotron facilities, and (iii) identify optimal experimental conditions of high-resolution SRXTM for fine-grained materials. SRXTM data of these shales were acquired under similar conditions at the Advanced Light Source (ALS) of Lawrence Berkeley National Laboratory, USA, the Advanced Photon Source (APS) of Argonne National Laboratory, USA, and the Swiss Light Source (SLS) of ...
Inaugurated in 1994, the ESRF is the worlds most intense x-ray source, a public center of excellence for fundamental research, also committed to applied and industrial research. Located in Grenoble, France, the ESRF is a model of international cooperation with 21 partner nations, of which 13 are Members and 8 are Scientific Associates.. The ESRF - the European Synchrotron Radiation Facility - is the most intense source of synchrotron-generated light, producing x-rays 100 billion times brighter than the x-rays used in hospitals. These x-rays, endowed with exceptional properties, are produced at the ESRF by the high energy electrons that race around the storage ring, a circular tunnel measuring 844 meters in circumference. Each year, the demand to use these x-ray beams increases and thousand of scientists from around the world come to Grenoble, to access the 43 highly specialized experimental stations, called beamlines, each equipped with state-of-the-art instrumentation, operating 24 hours a ...
Companies need to constantly look through the structure of materials to meet the current needs of society and the economy by developing new products and processes or improve existing ones, making them more efficient and cheap.. Research done with the use of synchrotron light sources have benefited the development of numerous products and components, from baby diapers to turbines for aircraft. They have been - and still are - used in the development of more durable, resistant and inexpensive batteries for electric cars, cellphones and laptops and the development of new semiconductors, capable of increasing the efficiency of organic solar cells for the production of electricity.. Among the largest US companies, according to Fortune magazines ranking, at least 32 of them use synchrotron light sources in the development of their products. Exxon Mobil, Chevron, General Electric, Ford Motor, HP, GM, IBM, Boeing, Johnson & Johnson, Pfizer, Novartis, Intel and 3M are among these companies.. Companies ...
News and bulletins about European Synchrotron Radiation Facility for biotechnology, life sciences, pharmacy, healthcare, diagnostics, bioinformatics, updated daily and relevant to the sector, can be found on this page.
Buy or Rent Medium-scale Synchrotron Radiation Facilities In Asia: Approaches To Effective And Versatile Use as an eTextbook and get instant access.
In the framework of the HL-LHC project, the vacuum performance of new surface material needs to be studied. In particular, a-C coating is proposed as an anti-multipactor surface in the HL-LHC Inner Triplets. Since the protons in the HL-LHC Inner Triplets will generate synchrotron radiation (SR) with ~ 10 eV critical energy and ~ 10^16 ph/m/s flux, it is therefore of great importance to study the impact of such photons on a-C coating held at room and cryogenic temperature and compare the results against present LHC material. This paper describes construction and parameters of experimental set-up based on new Synchrotron Radiation beamline from booster synchrotron BEP at BINP. The experimental program releasing in collaboration between CERN and BINP for performing measurements of photon stimulated gas desorption, photon distribution and photo-electron emission provoked by synchrotron radiation are presented ...
Cereal crops accumulate low levels of iron (Fe) of which only a small fraction (5-10%) is bioavailable in human diets. Extensive co-localization of Fe in outer grain tissues with phytic acid, a strong chelator of metal ions, results in the formation of insoluble complexes that cannot be digested by humans. Here we describe the use of synchrotron X-ray fluorescence microscopy (XFM) and high resolution secondary ion mass spectrometry (NanoSIMS) to map the distribution of Fe, zinc (Zn), phosphorus (P) and other elements in the aleurone and subaleurone layers of mature grain from wild-type and an Fe-enriched line of rice (Oryza sativa L.). The results obtained from both XFM and NanoSIMS indicated that most Fe was co-localized with P (indicative of phytic acid) in the aleurone layer but that a small amount of Fe, often present as hotspots, extended further into the subaleurone and outer endosperm in a pattern that was not co-localized with P. We hypothesize that Fe in subaleurone and outer ...
During FY 1997 Brookhaven National Laboratory celebrated its 50th Anniversary and 50 years of outstanding achievement under the management of Associated Universities, Inc. This progress report is divided into the following sections: (1) introduction; (2) science highlights; (3) meetings and workshops; (4) operations; (5) projects; (6) organization; and (7) abstracts and publications.
Powder diffraction was developed independently in 1916 by Peter Debye and Paul Scherrer in Germany and Albert Hull in the U.S. To commemorate this 100th anniversary, a half-day symposium on historical developments in powder diffraction as well as contemporary APS work was held on November 11, 2016.. Where the speakers have agreed, recordings of the talks and slides have been placed in youtube.. David Cox, Brookhaven National Laboratory (Retired) Some Recollections from the Early Days of Neutron and Synchrotron X-ray Powder Diffraction. Tim Fawcett, International Centre for Diffraction Data 100 Years of Powder Diffraction. Pete Chupas, Advanced Photon Source 80+ Years of Pair Distribution Function Measurements. Andrey Yakovenko, Advanced Photon Source New In-Situ Capabilities at 17-BM Rapid Acquisition Powder Diffraction Line. Saul Lapidus, Advanced Photon Source Improving On Great: The High-Resolution Powder Diffractometer, 11-BM. Olaf J. Borkiewicz, Advanced Photon Source Whats New ...
This paper describes the effects of intense synchrotron radiation beams from the Advanced Photon Source on small ferritin crystals suspended in solution. Typical powder diffraction, shown in the figure, identifies a number of individual crystals within the X-ray beam. After exposures in the range 2×107 Grays, the crystals were found to disintegrate suddenly in a spectacular way, as captured on the JSR cover image. The peak evolution to larger momentum transfer implies that the crystals collapse, possibly due to loss of hydration.. ...
This review updates the recent advances and applications of three prominent synchrotron radiation techniques, microprobe X-ray fluorescence spectroscopy/imaging, X-ray absorption spectroscopy, and infrared microspectroscopy, and highlights how these tools are useful to the medicinal chemist. A brief description of the principles of the techniques is given with emphasis on the advantages of using synchrotron radiation-based instrumentation rather than instruments using typical laboratory radiation sources. This review focuses on several recent applications of these techniques to solve inorganic medicinal chemistry problems, focusing on studies of cellular uptake, distribution, and biotransformation of established and potential therapeutic agents. The importance of using these synchrotron-based techniques to assist the development of, or validate the chemistry behind, drug design is discussed.
2018 The Author(s). Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0). Received: 11 February 2018 / Revised: 4 March 2018 / Accepted: 6 March 2018 / Published: 8 March 2018. (This article belongs to the Special Issue Processing-Structure-Properties Relationships in Polymers) This research used resources of the Advanced Photon Source (APS), a US Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract DE-AC02-06CH11357. The authors acknowledge all the staff at beamline 5-ID-D DND-CAT of the Advanced Photon Source (APS) at the Argonne National Laboratories, especially Steven Weigand and James Rix for their support before and during the synchrotron experiments. The authors acknowledge Mary Beth Kossuth at ...
X-ray synchrotron radiation pseudo-holotomography as a new imaging technique to investigate angiogenesis and bone regeneration in in vivo implanted engineered ...
The Stanford Synchrotron Radiation Lightsource (SSRL) provides synchrotron radiation, a name given to X-rays or light produced by electrons circulating in a storage ring at nearly the speed of light. These extremely bright X-rays can be used to investigate various forms of matter ranging from objects of atomic and molecular size to man-made materials with unusual properties.
Flow- or stretch-induced crystallization (FIC or SIC) is believed to be mainly responsible for the excellent mechanical properties of polymers during real service conditions. With the development of synchrotron radiation X-ray scattering, time resolution has been increased from minutes to millisecond, the in-situ tracing of the structural evolution of polymers under complex external fields becomes possible. Recently, the FIC behaviors of polymers (i.e. natural rubber and polyethylene) during multi-axial deformation like biaxial stretching, film blowing and balloon blowing have been systematically studied by our group with a series of custom-built experimental devices combined with synchrotron radiation X-ray scattering techniques. Considering the phenomenon of frustrating SIC for natural rubber during biaxial stretching, here we proposed a new model for SIC based on the results of theoretical calculation, which decouples the free energy contributions of chain orientation from that of ...
Last week, Frank Brenker and his colleagues Bart Vekemans, Laszlo Vincze, and Manfred Burghammer analyzed the first track to be extracted from the Stardust Interstellar Collector. We suspected that this is a particle that was ejected from an impact of a high-velocity particle (either an interplanetary dust particle or an interstellar dust particle) on the port (left-side) aft solar panel. We thought that this would be the case for two reasons. We mainly based this expectation on the trajectory - it appears to be pointing back to the aft solar panel - but also on the track shape - it does not show the shock-induced flaring that one usually sees with hypervelocity impacts. Dr. Brenker and colleagues used a highly focussed x-ray beam at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. ESRF is essentially an x-ray microscope the size of a shopping mall. The incredibly tight focus of this beam (about a tenth of a micron!) is ideal for the analysis of these very tiny samples. ...
The application of the X-ray phase-contrast `edge illumination principle to the highly coherent beams available at synchrotron radiation facilities is presented here. We show that, in this configuration, the technique allows achieving unprecedented angular sensitivity, of the order of few nanoradians. The results are obtained at beamlines of two different synchrotron radiation facilities, using various experimental conditions. In particular, different detectors and X-ray energies (12 keV and 85 keV) were employed, proving the flexibility of the method and the broad range of conditions over which it can be applied. Furthermore, the quantitative separation of absorption and refraction information, and the application of the edge illumination principle in combination with computed tomography, are also demonstrated. Thanks to its extremely high phase sensitivity and its flexible applicability, this technique will both improve the image quality achievable with X-ray phase-contrast imaging and allow ...
Here we report that the equation of state (EOS) of Mo is obtained by an integrated technique of laser-heated DAC and synchrotron X-ray diffraction. The cold compression and thermal expansion of Mo have been measured up to 80 GPa at 300 K, and 92 GPa at 3470 K, respectively. The P-V-T data have been treated with both thermodynamic and Mie-Gruneisen-Debye methods for the thermal EOS inversion. The results are self-consistent and in agreement with the static multi-anvil compression data of Litasov et al. (J. Appl. Phys. 113, 093507 (2013)) and the theoretical data of Zeng et al. (J. Phys. Chem. B 114, 298 (2010)). Furthermore, these high pressure and high temperature (HPHT) data with high precision firstly complement and close the gap between the resistive heating and the shock compression experiment. ...
Andrzej Joachimiak. Andrzej Joachimiak is an expert in synchrotron-based X-ray crystallography and structural biology. At Argonne, he has made significant contributions to the high-throughput crystallography using synchrotron radiation and the development of state-of-the-art facilities for macromolecular crystallography. The development and integration of the novel synchrotron beamlines, exploitation of the anomalous signal-based phasing methods in the third-generation environment and integration of hardware and software at the Structural Biology Center beamlines at the Advanced Photon Source contributed very strongly to the enhanced efficiency of such facilities worldwide.. ...
We describe the design and performance of the Los Alamos VUV synchrotron radiation beamline, U3C, on the VUV ring of the National Synchrotron Light Source at Brookhaven National Laboratory. The beamline uses separate function optics to collect and focus the horizontally and vertically diverging beam. The monochromator is a grazing incidence Roland circle instrument of the extended grasshopper design (ERG). A post monochromator refocusing mirror is used to focus or collimate the diverging beam from the monochromator. The beamline control and diagnostics systems are also discussed ...
Structural biology has developed rapidly over the last decade, driven by the various genome projects around the world and by advances in the field of biomolecular crystallisation. X-ray diffraction from macromolecular crystals is used to reveal the atomic arrangement of proteins, nucleic acids and viruses. In this respect, macromolecular crystallography is a powerful tool in the drug-design process. The outstanding properties of the X-ray beams provided by synchrotron radiation sources are now essential for collecting high-quality diffraction data. Pharmaceutical companies appreciate the rapid data collection on very small crystals and at higher resolution than with conventional X-ray sources.. The ESRFs crystallography beamlines have seen a large increase in demand for beamtime from industry in recent years. Companies are also requesting faster access to the synchrotron facilities. Therefore, a data collection service was set up, whereby the user sends their frozen samples to ESRF. The ...
TY - JOUR. T1 - Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase. AU - Pham, Khoa N.. AU - Lewis-Ballester, Ariel. AU - Yeh, Syun Ru. N1 - Funding Information: We thank Dr. Denis L. Rousseau for helpful discussions. The structural data were collected by the Lilly Research Laboratories Collaborative Access Team (LRL-CAT) beamline staff at Sector 31 of the Advanced Photon Source. This research used resources of the Advanced Photon Source, a US Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357. Use of the Lilly Research Laboratories Collaborative Access Team (LRL-CAT) beamline at Sector 31 of the Advanced Photon Source was provided by Eli Lilly Company, which operates the facility. This work was supported by National Institute of Health Grant GM115773 and GM126297 to S.-R.Y. Publisher Copyright: Copyright © 2019 American ...
The CAT end station of the CAT-ACT beamline at ANKA is dedicated to catalytic research using X-ray spectroscopic techniques. It will be operated by the Grunwaldt group at the Institute for Chemical Technology and Polymer Chemistry (http://www.itcp.kit.edu/grunwaldt/) and the Institute of Catalysis Research and Technology (http://www.ikft.kit.edu/234.php).. Synchrotron radiation based techniques have evolved as key speciation methods in catalysis research, especially with respect to in-situ and in-operando X-ray based characterization techniques as a basis for a rational design of heterogeneous catalysts. Knowledge of oxidation state and coordination environment of the catalytically active centers, nanoparticle morphology etc. contributed significantly to a deeper understanding of heterogeneously catalyzed reactions and serves today as a basis for the design of new catalysts and for first-principles kinetic modeling. The beamline design places emphasis on in situ X-ray Absorption Spectroscopy ...
The Stanford Synchrotron Radiation Lightsource (SSRL) at the SLAC National Accelerator Laboratory is a national synchrotron x-ray research facility funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences.
The Stanford Synchrotron Radiation Lightsource (SSRL) at the SLAC National Accelerator Laboratory is a national synchrotron x-ray research facility funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences.
The figure above depicts the s-SNOM setup used in the published work using two different sources, a tunable narrow band quantum cascade laser (QCL) and the synchrotron broadband IR beam. As an innovation brought by the research, the synchrotron setup used a classic symmetric Michelson interferometer for Fourier processing the data as an alternative to the standard asymmetric scheme typically used in s-SNOM. Better SNR related to increased optical power at the sample and higher mechanical stability highlight the instrumental advances of the research. The work explored the interferometric properties of the far-field background arising from tip-sample geometrical scattering and developed a model for retrieving the near-field phase, and consequently the absorption properties, of a variety of samples such as poly(methyl methacrylate) (PMMA), poly(dimethylsiloxane) (PDMS), explosive polymers 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) and pentaerythritol tetranitrate (PETN), and Bovine Serum Albumin ...
Contacts: Peter Genzer, (631) 344-3174 | Written by Chelsea WhytePrint The University of California, Riverside issued the following release on Wednesday, Jan. 16. X-ray diffraction and microdiffraction studies for this work were conducted at beamlines X13B and X6B at the National Synchrotron Light Source, with the help of Brookhaven physicist, co-author Elaine DiMasi. For more information about Brookhavens role, contact Chelsea Whyte, [email protected], 631-344-8671, or Peter Genzer,
SPring-8 is a third-generation synchrotron radiation facility, and provides the most powerful synchrotron radiation currently available. SPring-8 is being widely opened for domestic and foreign researchers to strengthen advanced research in fundamental science and industrial applications and so forth.The Japan Synchrotron Radiation Research Institute (JASRI) is responsible for the management, operation and development of the facility.
SPring-8 is a third-generation synchrotron radiation facility, and provides the most powerful synchrotron radiation currently available. SPring-8 is being widely opened for domestic and foreign researchers to strengthen advanced research in fundamental science and industrial applications and so forth.The Japan Synchrotron Radiation Research Institute (JASRI) is responsible for the management, operation and development of the facility.
The temperature sensitivity of vaccines and therapeutic proteins forces the distribution of life-saving treatments to rely heavily on the temperature-controlled (usually 2-8 degrees C) supply and distribution network known as the cold chain. Here, using avidin as a model, we demonstrate how surface engineering could significantly increase the thermal stability of therapeutic proteins. A combination of spectroscopic (Fourier transform infrared, circular dichroism, and ultraviolet-visible) and scattering techniques (dynamic light scattering, small-angle, and wide-angle X-ray scattering) were deployed to probe the activity, structure, and stability of the model protein. Temperature-dependent synchrotron radiation circular dichroism spectroscopy was used to demonstrate a significant increase in thermal stability, with a half denaturation temperature of 139.0 degrees C and reversible unfolding with modified avidin returning to a 90% folded state when heated to temperatures below 100 degrees C. ...
The Protein Circular Dichroism Data Bank (PCDDB) is a web-based resource containing circular dichroism (CD) and synchrotron radiation circular dichroism spectral and associated metadata located at http://pcddb.cryst.bbk.ac.uk. This resource provides a freely available, user-friendly means of accessing validated CD spectra and their associated experimental details and metadata, thereby enabling broad usage of this material and new developments across the structural biology, chemistry, and bioinformatics communities. The resource also enables researchers utilizing CD as an experimental technique to have a means of storing their data at a secure site from which it is easily retrievable, thereby making their results publicly accessible, a current requirement of many grant-funding agencies world-wide, as well as meeting the data-sharing requirements for journal publications. This tutorial provides extensive information on searching, accessing, and downloading procedures for those who wish to utilize ...
Addressing global challenges. The ESRF is a centre of excellence for fundamental research, also committed to applied and industrial research. It contributes to overcoming the societal and environmental challenges facing the world.. ...
Addressing global challenges. The ESRF is a centre of excellence for fundamental research, also committed to applied and industrial research. It contributes to overcoming the global challenges facing the world.. ...
Sutherland, J. C., Dec 1 2009, Modern Techniques for Circular Dichroism and Synchrotron Radiation Circular Dichroism Spectroscopy. Wallace, B. A. & Janes, R. W. (eds.). p. 19-72 54 p. (Advances in Biomedical Spectroscopy; vol. 1).. Research output: Chapter in Book/Report/Conference proceeding › Chapter ...
The gadolinium-based nanoagent named AGuIX ® is a unique radiosensitizer and contrast agent which improves the performance of radiotherapy and medical imaging. Currently tested in clinical trials, AGuIX ® is administrated to patients via intravenous injection. The presence of nanoparticles in the blood stream may induce harmful effects due to undesired interactions with blood components. Thus, there is an emerging need to understand the impact of these nanoagents when meeting blood proteins. In this work, the influence of nanoagents on the structure and stability of the most abundant blood protein, human serum albumin, is presented. Synchrotron radiation circular dichroism showed that AGuIX ® does not bind to the protein, even at the high ratio of 45 nanoparticles per protein at 3 mg/L. However, it increases the stability of the albumin. Isothermal thermodynamic calorimetry and fluorescence emission spectroscopy demonstrated that the effect is due to preferential hydration processes. Thus, this study
Day, L., Zhai, J., Xu, M., Jones, N. C., Hoffmann, S. V., & Wooster, T. J. (2014). Conformational changes of globular proteins adsorbed at oil-in-water emulsion interfaces examined by synchrotron radiation circular dichroism. Food Hydrocolloids, 34, 78-87. doi: 10.1016/j.foodhyd.2012.12.015.. Zhai, J. L., Day, L., Aguilar, M. I., & Wooster, T. J. (2013). Protein folding at emulsion oil/water interfaces. Current Opinion in Colloid and Interface Science, 18(4), 257-271. doi: 10.1016/j.cocis.2013.03.002.. ...
EMBL Grenoble collaborates with the Structural Biology group at the ESRF (European Synchrotron Radiation Facility) in the design, construction, operation and development of synchrotron beamlines for macromolecular crystallography (MX) and small angle X-ray scattering (SAXS).
The Proton Synchrotron Booster (PSB), a synchrotron, is the first and smallest circular proton accelerator in the accelerator chain at the CERN Large Hadron Collider injection complex. It contains four superimposed rings with a radius of 25 meters, which take protons with an energy of 6988801088243500000♠50 MeV from the linear accelerator LINAC 2 and accelerate them up to 6990224304708179999♠1.4 GeV, ready to be injected into the Proton Synchrotron. Before the PSB was built in 1972, LINAC 2 injected directly into the Proton Synchrotron, but the greater injection energy provided by the booster allows more protons to be injected and a higher luminosity at the end of the accelerator chain. As part of the High Luminosity Large Hadron Collider upgrade, the PSBs injection energy is being increased for the same reason. LINAC 2 is being replaced by LINAC 4, which will provide an energy of 6989256348237920000♠160 MeV into the PSB. Another way LINAC 4 will enable the PSB to hold more protons is by ...
X-ray Talbot interferometry, which uses two transmission gratings, has the advantage that broad energy bandwidth x-rays can be used. We demonstrate the use of white synchrotron radiation for high-speed X-ray phase imaging and tomography in combination with an X-ray Talbot interferometer. The moiré fringe visibility over 20% was attained, enabling quantitative phase measurement. X-ray phase images with a frame rate of 500 f/s and an X-ray phase tomogram with a scan time of 0.5 s were obtained successfully. This result suggests a breakthrough for time-resolved three-dimensional observation of objects that weakly absorb X-rays, such as soft material and biological objects.. ©2009 Optical Society of America. Full Article , PDF Article ...
Vertebrate hard tissues first appeared in the dermal skeletons of early jawless vertebrates (ostracoderms) and were further modified in the earliest jawed vertebrates. Fortunately, histological information is usually preserved in these early vertebrate fossils and has thus been studied for more than a century, done so by examining thin sections, which provide general information about the specific features of vertebrate hard tissues in their earliest forms. Recent progress in synchrotron X-ray microtomography technology has caused a revolution in imaging methods used to study the dermal skeletons of early vertebrates. Virtual thin sections obtained in this manner can be used to reconstruct the internal structures of dermal skeletons in three-dimensions (3D), such as vasculature, buried odontodes (tooth-like unites) and osteocytes. Several body scales of early vertebrates have been examined using this imaging method and in situ 3D models of internal structures are created. Andreolepis (an early ...
Characterizations of stored electron beams and more recently positron beams circulating in the Advanced Photon Source (APS) 7-GeV storage ring have been done using optical synchrotron radiation (SR) and x-ray synchrotron radiation (XSR) imaging techniques. Results include the measurement of the bunch length and horizontal beam size versus single-bunch current for both electron and positron beams, observations of multibunch bunch length effects near 100 mA stored beam current, and initial diagnostics of a coupled-bunch instability with 15-minute period. Both the Hamamatsu C5680 dual-sweep streak camera using OSR and a pinhole camera using XSR from a bending magnet source point were utilized. Proposed enhancements to the beamline will also be presented.
The ASTRA Toolbox is a MATLAB and Python platform providing scalable, high-performance GPU primitives for 2D and 3D tomography, including building blocks for advanced reconstruction algorithms. One of its main design goals is geometric flexibility, allowing the toolbox to be used with many types of experimental setups.. The ASTRA Toolbox has been developed jointly by the Computational Imaging group of CWI, and the University of Antwerp. It is used in tomographic imaging research by academics working on novel algorithms and in experimental imaging labs. It is also deployed by several industrial partners as the core of the reconstruction software in their imaging equipment and applications. Furthermore, the toolbox is a main component in a number of other applications, including software used at two of the largest synchrotrons in the world: the European Synchrotron Radiation Facility (ESRF) in Grenoble, and the Advanced Photon Source (APS) in Chicago. ...
The influence of strain rate on development of deformation texture under a dynamic shock compression of a 904L stainless steel was quantitatively investigated using synchrotron X-ray diffraction and crystallographic orientation distribution function (ODF) analysis. The Split-Hopkinson Pressure Bar (SHPB) technique was used to generate a high strain rate of andgt; 10(3) s(-1) for preparing the deformed samples. Starting with an almost random texture in a solution treatment condition, the deformed material developed several typical texture components, such as Goss texture and Brass texture. Compared to the texture components displayed in the state of quasi-static compression deformation, it was found that the high-speed deformation generated much weaker texture components. In combination with the change in microstructures observed by electron backscattering diffraction (EBSD) and the transmission electron microscopy (TEM) technique, the high-energy X-ray diffraction provides a powerful tool for ...
Sznitman, J; Sutter, R; Altorfer, D; Stampanoni, M; Rösgen, T; Schittny, J C (2010). Visualization of respiratory flows from 3D reconstructed alveolar airspaces using X-ray tomographic microscopy. Journal of Visualization, 13(4):337-345. ...
Comparison of synchrotron radiation and conventional X-ray microcomputed tomography for assessing trabecular bone microarchitecture of human femoral ...
Accelerators like the National Synchrotron Light Source (NSLS) II fire particles around a circular tunnel to nearly the speed of light. But as electrons curve around the ring, they lose energy in the form of light. Rather than think of this as a defect, researchers at Brookhaven National Laboratory found a way to harness this excess light and use it to understand the world at its most fundamental level. This basic research, however, can lead to remarkable and practical results. Considering the original NSLS at Brookhaven helped win two Nobel prizes, create better HIV treatments and rethink the battery, this increase in performance will likely open the door to groundbreaking new discoveries.. ...
Abstract: Background: As a novel approach to solve the protein structure, serial femtosecond crystallography (SFX) has been developed rapidly owing to the advantages of the room-temperature data collection, lower radiation damage and time-resolved study. The first X-ray free-electron laser (XFEL) based SFX experiment has offered a new method to structure determination of protein microcrystals successfully. Purpose:The aim is to introduce SFX into the widely-available third-generation synchrotron radiation (SR). Methods: The electrospinning sample delivery system is a potential method to be applied on SR. The theoretical and experimental researches on electrospinning were studied using BL17U1 beamline in Shanghai synchrotron radiation facility (SSRF). Results: A microjet containing microcrystals was produced from the liquid meniscus and controlled by an electrostatic field. The air ionization problem disturbing electrospinning in SR experiment was solved by providing vacuum condition and coaxial ...
In order to investigate FeSO4, ZnSO4 (the two of main metal compositions of Shanghai PM2.5 (particle matter with those aerodynamical diameter |2.5 mu m)) effects on acute lung injury, six solutions contained PM2.5 aerosol particles, FeSO4, ZnSO4 and their mixtures were instilled intratracheally into mouse lungs for experiment. By 2 days. after instillation, the live mice were checked in vivo by synchrotron refractive index microradiography. In addition after extracted and examined by dissection, the right lobes of lung were fixed by formalin, then imaged by synchrotron microradiography again. Corresponding parts of those lung tissues were embedded in paraffin for histopathologic study. The synchrotron X-ray microradiographs of live mouse lung showed different lung texture changes after instilled with different toxic solutions. Hemorrhage points in lung were observed more from those mice instilled by FeSO4 contained toxin solutions groups. Bronchial epithelial hyperplasia can be observed in ZnSO4
Presented here is a protocol for cell culture on silicon nitride membranes and plunge-freezing prior to X-ray fluorescence imaging with ...
A radiation-based timer for use in an implantable medical device (IMD) includes a radiation source and a radiation detection circuit. The radiation source emits radiation particles during a process referred to as radioactive decay. The radiation detection circuit detects the radiation particles emitted during the decay process and tracks the number of radiation particles detected. When the number of radiation particles detected reaches a threshold value, a timer signal is generated. In this manner, the radiation-based timer generates a timer signal as a function of the radioactive decay of the radiation source. The timer signal may be used by one or more components of the IMD for any of a number of functions, including as a wakeup trigger for a communications and/or a sensor event.
Micro-X-ray absorption near-edge structure (μ-XANES) spectroscopy has been used by several recent studies to determine the oxidation state and coordination of iron in silicate glasses. Here, we present new results from Fe μ-XANES analyses on a set of 19 Fe-bearing felsic glasses and 9 basaltic glasses with known, independently determined, iron oxidation state. Some of these glasses were measured previously via Fe XANES (7 rhyolitic, 9 basaltic glasses; Cottrell et al. 2009), while most felsic reference glasses (12) were analyzed for the first time. The main purpose of this study was to understand how small changes in glass composition, especially at the evolved end of silicate melt compositions occurring in nature, may affect a calibration of the Fe μ-XANES method.. We performed Fe μ-XANES analyses at different synchrotron radiation sources [Advanced Photon Source (APS), Argonne, U.S.A., and Angströmquelle Karlsruhe (ANKA), Germany] and compared our results to existing calibrations obtained ...
TY - JOUR. T1 - Novel rhenium(V) nitride complexes with dithiocarbimate ligands. T2 - A synchrotron X-ray and DFT structural investigation. AU - Perils, Joanne. AU - Cortezon-Tamarit, Fernando. AU - Kuganathan, Navaratnarajah. AU - Kociok-Köhn, Gabriele. AU - Dilworth, Jonathan R. AU - Pascu, Sofia I.. PY - 2018/4/24. Y1 - 2018/4/24. N2 - The application of rhenium complexes as therapeutic agents in nuclear medicine has propelled research into the chemistry of these compounds. In our effort to develop and investigate new therapeutic radiopharmaceuticals based on the complexes of rhenium we have investigated the nitride core, [ReN]2+. This work looks at the behavior of sulfonamide based dithiocarbimates towards the rhenium(V) nitride core. The aim here was to prepare anionic complexes with aromatic as well as fluorescent aromatic groups in the sulfonamide substituent located on the dithiocarbimate backbone. We envisaged that the polar sulfonamide and dianionic charge would confer solubility in ...
...SASKATOON SASKATCHEWAN Canadian Light Source (CLS) staff scientist Lu... The advantage to using microscopes with synchrotron light is that it ...The team analyzed preserved samples of healthy and diseased tissue tha...Barretts Esophagus (BE) occurs when the cells that normally line the ...,University,of,Saskatchewan,and,Canadian,Synchrotron,researchers,shed,light,on,esophageal,disease,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
We thank Prof. Dr. Wolfgang Baehr (University of Utah, USA) for providing us PrBP/δ expression vector. We are obliged to Ms. Ingrid Semjonow, Ms. Helena Seibel and Mr. Brian Bauer for their excellent technical assistance in purifying reagents and in protein preparations. We are grateful to Uwe Müller, Manfred Weiss and the scientific staff of the BESSY-MX/Helmholtz Zentrum Berlin für Materialien und Energie at beamlines BL14.1, BL14.2 and BL14.3 operated by the Joint Berlin MX-Laboratory at the BESSY II electron storage ring (Berlin-Adlershof, Germany) and the scientific staff of the European Synchrotron Radiation Facility (ESRF, Grenoble) at beamlines ID14-1, ID14-4, ID23-1, ID23-2, ID30A, ID30B and ID29, where the data were collected, for continuous support. This work was supported by grants from the Deutsche Forschungsgemeinschaft (SFB740 to T.M., C.M.T.S, M.H., P.S.; SFB1078-B6 to P.S.; SFB958 to C.M.T.S.), DFG Cluster of Excellence Unifying Concepts in Catalysis (Research Field D/E to ...
The penetrating power of X-rays coupled with the high flux of 3rd generation synchrotron sources makes X-ray tomography to excel among fast imaging methods . To exploit this asset of synchrotron sources is the motivation for setting up an ultra-fast tomography endstation at the TOMCAT beamline. The state of the art instruments at synchrotron sources offer routinely a temporal resolution of tens of seconds in tomography. For a number of applications, for example biomedical studies, the relevant time scales (breathing, heartbeat) are rather in the range of 0.5-2 seconds. To overcome motion artifacts when imaging such systems a new ultra-fast tomographic data acquisition scheme is being developed at the TOMCAT beamline. We can acquire a full set of projections at sub-second timescale in monochromatic or white-beam configuration. We present a feasibility study with the ultimate aim to achieve sub-second temporal resolution in 3D without significant deterioration of the spatial resolution. For the ...
In this study, the course of myofibrillogenesis in Drosophila pupae was followed by means of conventional X-ray diffraction and end-on microdiffraction. Owing to the high transmission of X-ray beams, the diffraction technique is suitable for detecting overall regularity in molecular arrangement in bulk specimens such as the thoraces of insects. With the wavelength of the X-ray used here (0.1 nm), this technique will be applicable to larger insects, including honeybees and silkworm moths. In the conventional X-ray diffraction recordings, in which the beamsize is comparable to the size of a Drosophila thorax (approx. 1 mm), the extent of development of thoracic musculature can be diagnosed with a single shot of chest X-ray. This is a non-invasive method requiring relatively low doses of X-rays and may be incorporated for routine checks of developmental status and/or quick assessment of effect of mutations on flight muscle-related genes. On the other hand, the end-on microdiffraction recording is ...
The European Synchrotron Radiation Facility Medical Research Beamline is now fully operational. One of the primary programs is the development of dual-energy transvenous coronary angiography for in vivo human research protocols. Previous work at this and other synchrotrons has been entirely devoted to the use of the dual-energy digital subtraction technique at the iodine k-absorption edge at 33.17 keV. The images are recorded in a line scan mode following venous injection of the contrast agent. Considerations of the patient dose, the dilution of the contrast agent in the pulmonary system and the arteries overlying the filled ventricles have limited the image quality. The ESRF facility was designed to allow dual- energy imaging at higher energies, for example at the gadolinium k-absorption edge at 50.24 keV. The advantages have been theoretically known for many years, with the higher energy promising higher image quality with less radiation dose. During the commissioning phase of the ESRF ...
Nanoflake/graphite Fibers EI 作者:Liu, Zhihe ;Tan, Hua ;Liu, Daobin ;Liu, Xiaobiao ;Xin, Jianping ;Xie, Junfeng ;Zhao, Mingwen ;Song, Li ;Dai, Liming ;Liu, Hong 作者机构:[Liu, Zhihe ;Liu, Hong ] Institute for Advanced Interdisciplinary Research (IAIR), University of Jinan, Shandong; 250022, China;[Liu, Daobin ;Song, Li ] National Synchrotron Radiation Laboratory CAS Hefei Science Center University of Science and Technology of China Hefei, Anhui; 230026, China;[Liu, Zhihe ;Tan, Hua ;Xin, Jianping ;Liu, Hong ] State Key Laboratory of Crystal Materials, Shandong University, Jinan; Shandong; 250100, China;[Xie, Junfeng ] College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan; 250014, China;[Liu, Xiaobiao ;Zhao, Mingwen ] School of Physics and Microelectronics, Shandong University Jinan, Shandong; 250100, China;[Dai, Liming ] Center of Advanced Science and Engineering for Carbon (Case4carbon), Department of Macromolecular Science and Engineering, ...
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Earth Sciences, Department of Earth Sciences. Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Earth Sciences, Department of Earth Sciences, Solid Earth Geology. ...
Synchrotron-based micro X-ray absorption spectroscopy (micro-XAS) in combination with micro X-ray fluorescence (micro-XRF) and micro X-ray diffraction (micro-XRD) are powerful tools for spatially resolved micro-scale investigations of retention processes in heterogeneous systems. We have successfully applied these techniques in the investigations of uptake processes in argillaceous rocks and hardened cement paste. Here one of the essential questions is On what mineral phase or phases is sorption occurring in the complex mineral assemblage? and Is it the same phase(s) assumed in the modeling? In some cases minor minerals may well be important. Furthermore, we were able to shine light into the alkali-aggregate reaction, which is a severe alteration process limiting the lifetime of concrete structures exposed to water or moisture ...
An initial tranche of results from day-to-day use of a robotic system for setting up 100 nl-scale vapour-diffusion sitting-drop protein crystallizations has been surveyed. The database of over 50 unrelated samples represents a snapshot of projects currently at the stage of crystallization trials in Oxford research groups and as such encompasses a broad range of proteins. The results indicate that the nanolitre-scale methodology consistently identifies more crystallization conditions than traditional hand-pipetting-style methods; however, in a number of cases successful scale-up is then problematic. Crystals grown in the initial 100 nl-scale drops have in the majority of cases allowed useful characterization of X-ray diffraction, either in-house or at synchrotron beamlines. For a significant number of projects, full X-ray diffraction data sets have been collected to 3 Šresolution or better (either in-house or at the synchrotron) from crystals grown at the 100 nl scale. To date, five structures ...
A photovoltaic device comprises an upper cell and a lower cell separated by an electrically insulating layer. The cells and the layers are fabricated as a single monolithic structure, and separate electrical contacts are provided for the upper and lower cells to allow independent extraction of current from each cell. The upper cell has a larger bandgap than the lower cell so that incident low energy photons unabsorbed and unconverted by the upper cell can propagate through to the lower cell for conversion. The two bandgaps can be selected to accommodate spectral ranges of interest. The device is incorporated into a system including two sources of photons with different wavelength ranges associated with the bandgaps of the two cells, such that each cell can convert photons from one source. One source may be the sun and the other may be a local photon source such as a thermal source. Alternatively, both photon sources may be local sources. Operation of the device can be further optimised and
The J. Bennett Johnston, Sr., Center for Advanced Microstructures and Devices (CAMD), is named for the father of its congressional sponsor, Senator J. Bennett Johnston, Jr. of Louisiana. CAMD is a synchrotron radiation research center at Louisiana State University in Baton Rouge. The mission of CAMD is to provide infrastructure for research and education in synchrotron-based science and technology. The facility was built with a $25-million grant from the U.S. Department of Energy and its operations are state-funded by LSU. The heart of the facility is a 1.3 GeV electron storage ring that was built exclusively to provide synchrotron radiation. Research in basic sciences and microfabrication is conducted by scientist and engineers from Louisiana universities, along with distinguished scientists from national and international institutions. ...
Norwegian and International Researchers can apply for the Fellowship.. Scholarship Description: The PhD project will be in the field of structural biology on a project entitled Bacterial toxins - Structure, function and molecular interactions . The project will ideally combine biophysical characterization (foremost by X-ray crystallography) with cell biological investigations. It is anticipated that the project will include a research stay at a foreign institution such as the European Synchrotron Radiation Facility (ESRF), Grenoble. The project can be expanded to involve collaborations with Michele Cascella (computational chemistry) and Kirsten Sandvig (cell biology).. Number of award(s): One PhD research fellowship is available.. Duration of award(s): The fellowship will be for a period of 4 years, with 25 % compulsory work (teaching responsibilities at the Department). Otherwise, the fellowship will be for a period of 3 years, with no compulsory work.. What does it cover? Position code 1017, ...
CHDI Foundation, Inc., a biomedical research organization exclusively focused on developing disease-modifying therapies for HD, is working with BioFocus, a drug discovery provider, to solve the structure of the active caspase-6 and in complex with inhibitors, with a view towards developing caspase-6 specific drugs. Using mosquito® Crystal for automated low-volume crystal screening, BioFocus identified crystallization conditions for apo-caspase-6 in the active state (PDB ID 3P45), in complex with the reversible inhibitor Ac-VEID-CHO (PDB ID 3P4U), as well as in complex with the irreversible inhibitor Z-VAD-FMK (PDB ID 3QNW). Optimization of the crystallization conditions of the irreversible inhibitor yielded plate-like crystals typically only 10-20 μm thick, which required synchrotron light to gain sufficient optical resolution.. ...
The DXAS beamline is an experimental station dedicated to dispersive x-ray absorption spectroscopy (acronym for DXAS) techniques, in the hard x-ray energy range (5 to 14 keV). The peculiarity of this beamline is the capability to collect absorption spectra over an extended range of photon energies without any mechanical movement of its optical elements. The DXAS is especially suited for detecting weak signals in XANES (X-ray Absorption Near-Edge Spectroscopy) and XMCD (X-ray Magnetic Circular Dichroism) experiments and for tracking time-dependent evolution of chemical reactions.. DXAS is installed on a 1.67T bending-magnet source, and it was opened to users in 2005. The beamline is comprised by the synchrotron light source, a vertically focusing bendable mirror, a bent crystal polychromator, and an area detector. The beam path over the optical elements starts when it hits the bendable mirror, used for vertical focusing as well as harmonic rejection. Then the light beam impinges onto a ...
TY - JOUR. T1 - Controlling N-doping type in carbon to boost single-atom site Cu catalyzed transfer hydrogenation of quinoline. AU - Zhang, Jian. AU - Zheng, Caiyan. AU - Zhang, Maolin. AU - Qiu, Yajun. AU - Xu, Qi. AU - Cheong, Weng Chon. AU - Chen, Wenxing. AU - Zheng, Lirong. AU - Gu, Lin. AU - Hu, Zhengpeng. AU - Wang, Dingsheng. AU - Li, Yadong. N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was supported by the National Key R&D Program of China (Nos. 2018YFA0702003 and 2016YFA0202801), the National Natural Science Foundation of China (Nos. 21890383, 21671117, 21871159, and 21901135), the National Postdoctoral Program for Innovative Talents, the Shuimu Tsinghua Scholar, Science and Technology Key Project of Guangdong Province of China (No. 2020B010188002), and Beijing Municipal Science & Technology Commission (No. Z191100007219003). We thank the BL14W1 station in Shanghai Synchrotron Radiation Facility (SSRF) and 1W1B station for XAFS measurement in ...
A research project, published this week in the journal Nature, sheds light on the bizarre halszkaraptor - a dinosaur so unusual that scientists are hailing it as a new species. What is very special about it is that it looks very weird. It doesnt look like any other dinosaur that we know so far, Vincent Fernandez, a paleontologist at the European Synchrotron Radiation Facility and co-author of the study, told The Guardian. About the size of a goose, the dinosaur boasted a long tail, a curved, elegant neck and a duck-like bill. While that may seem all bird to you, the halszkaraptor is considered non-avian. Its also a close cousin to the Cretaceous Periods famously ferocious velociraptor.
The RF gymnastics involved in the delivery of proton and lead ion bunches to the LHC can result in satellite bunches of varying intensity occupying the nominally empty RF buckets. Quantification of these satellites is crucial for bunch-by-bunch luminosity normalization as well as for machine protection. We present an overview of the longitudinal density monitor (LDM) which is the principal instrument for the measurement of satellite bunches in the LHC. The LDM uses single photon counting of synchrotron light. The very high energies reached in the LHC, combined with a dedicated undulator for diagnostics, allow synchrotron light measurements to be made with both protons and heavy ions. The arrival times of photons are collected over a few million turns, with the resulting histogram corrected for the effects of the detectors deadtime and afterpulsing in order to reconstruct the longitudinal profile of the entire LHC ring. The LDM has achieved a dynamic range in excess of 105 and a time resolution ...
TY - JOUR. T1 - Response to Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1.9 Å resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847. AU - Ramesh, Pandian. AU - Sundaresan, S. S.. AU - Sathya Moorthy, Pon. AU - Balasubramanian, M.. AU - Ponnuswamy, M. N.. PY - 2014/7. Y1 - 2014/7. UR - http://www.scopus.com/inward/record.url?scp=84903582799&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84903582799&partnerID=8YFLogxK. U2 - 10.1107/S1600577514010285. DO - 10.1107/S1600577514010285. M3 - Letter. C2 - 24971984. AN - SCOPUS:84903582799. VL - 21. JO - Journal of Synchrotron Radiation. JF - Journal of Synchrotron Radiation. SN - 0909-0495. IS - 4. ER - ...
TY - JOUR. T1 - Liquid Structure of CO2-Reactive Aprotic Heterocyclic Anion Ionic Liquids from X-ray Scattering and Molecular Dynamics. AU - Sheridan, Quintin R.. AU - Oh, Seungmin. AU - Morales-Collazo, Oscar. AU - Castner, Edward W.. AU - Brennecke, Joan F.. AU - Maginn, Edward J.. N1 - Funding Information: Support for the work of Q.R.S. and E.J.M. was provided by the Air Force Office of Scientific Research under AFOSR award number FA9550-14-1-0306. Computational resources were provided by the Notre Dame Center for Research Computing. Claudio Margulis and Jeevapani J. Hettige are acknowledged for their help with the structure function calculations. We acknowledge time on beamline 11-ID-B at the Argonne National Laboratory Advanced Photon Source under APS General User Proposal GUP-43233. For experimental support at APS beamline 11-ID-B, we thank Dr. Olaf J. Borkiewicz and Mr. Kevin A. Beyer. E.W.C. was supported by NSF grant number CHE-1362272. J.F.B. and S.O. acknowledge financial support from ...
We have measured the stability of a variety of photodiodes exposed to 157-nm light from a pulsed excimer laser by using a radiometry beamline at the Synchrotron Ultraviolet Radiation Facility at the National Institute of Standards and Technology. The intense, pulsed laser light exposed the photodiodes, whereas the low-intensity, continuously tunable light from the synchrotron source measured changes in the characteristics of the photodiodes, such as in the responsivity and the reflectance from the surface of a photodiode. Photodiodes studied include both silicon pn-junction and Schottky-barrier types. Among these photodiodes, we found that the damage mechanism for photodiodes with SiO2-based passivating layers is mainly the buildup of SiO2-Si interface trap states. The interface trap state buildup is well known for other semiconductor devices and is generally recognized as a product induced by radiation with an energy more than the 9-eV SiO2 bandgap energy rather than the 7.9-eV energy of the ...
Diamond is the UKs national synchrotron science facility. Its shaped like a huge ring, and is a bit like a giant microscope. Diamond speeds up electrons to near light speeds, producing a light 10 billion times brighter than the sun. These bright beams are then directed off into laboratories known as beamlines; here scientists use the light to study everything from viruses and vaccines to fossils and jet engines.. Diamond is one of the most advanced scientific facilities in the world, and its pioneering capabilities are helping to keep the UK at the forefront of scientific research. Here you can read about cutting-edge scientific research taking place at the synchrotron; and find out when your next chance is to visit Diamond. So take a look around, and find out what lies within the walls of the synchrotron.. ...
The purpose of this research is to develop improved diagnostic and treatment tools for prostate cancer in humans through the use of a canine (dog) model and a synchrotron-based x-ray source for imaging and therapy at the Canadian Light Source (CLS). Novel techniques in synchrotron x-ray imaging, specifically in-line phase contrast CT (PC-CT), will be explored as a valuable method for research and clinical imaging of spontaneous canine prostatic diseases as a model for human diseases. ...
Intimately intergrown micron-scale framboidal pyrite, carbonaceous material (CM), chalcopyrite, sphalerite and cobaltite form polyframboids in prehnite-pumpellyite facies rocks of the Otago Schist, New Zealand. This study quantifies the metal contents of these polyframboids using synchrotron X-ray fluorescence (SXRF) and laser ablation inductively coupled plasma spectrometry (LA-ICP-MS). Trace elements Au, Zn, As, Mo, Co, Ni, Cu, Ag and Pb are significantly enriched in the polyframboids. The distribution of Zn most closely follows that of CM, and was probably absorbed into the structure of the polyframboids during biogenic processes. The concentrations of Au and Ag are positively corrected with the Zn concentration in the polyframboids (R2 of Au-Zn and Ag-Zn are 0.81 and 0.89, respectively.). The concentration of other trace elements, such as As, Co and Cu, which occur adjacent to Zn on elemental maps, show a weak relationship with Zn and may have been incorporated into the polyframboids during ...
Abstract: Inductively coupled plasma mass spectrometry (ICP-MS) was used to quantify the total amount of trace elements in retina from adult male Sprague-Dawley rats (n = 6). Concentration of trace elements within individual retinal areas in frozen sections of the fellow eye was established with the use of two methodologies: (1) particle-induced X-ray emission (PIXE) in combination with 3D depth profiling with Rutherford backscattering spectrometry (RBS) and (2) synchrotron X-ray fluorescence (SXRF) microscopy. The most abundant metal in the retina was zinc, followed by iron and copper. Nickel, manganese, chromium, cobalt, selenium and cadmium were present in very small amounts. The PIXE and SXRF analysis yielded a non-homogenous pattern distribution of metals in the retina. Relatively high levels of zinc were found in the inner part of the photoreceptor inner segments (RIS)/outer limiting membrane (OLM), inner nuclear layer and plexiform layers. Iron was found to accumulate in the retinal ...
An interview with Dr. Gerry McDermott of the National Center for X-ray Tomography. Dr. Biology tours the synchrotron that is also called the giant monster. Dr. Biology learns how the football sized facility is used to power a new kind of microscope.. Content Info , Transcript ...
Porphyrin-based materials are prime candidates for solar energy harvesting applications. New compounds incorporating the porphyrin core, which exhibit the columnar liquid crystal (LC) phase, were synthesized as they offer a route to obtaining defect-free large area monodomain films. The structure of the phases exhibited by these materials has been probed by synchrotron X-ray diffraction with a microfocus (14ím x14 ím) beam. Exploiting the multidomain nature (i.e., having differently oriented crystal axes) of a thin glass cell, it was possible to obtain complete structural information without the need to have one single macroscopic crystal, which is normally difficult to obtain. The results confirmed the existence of the isotropic, discotic (columnar) LC, and discotic-ordered LC phases in these materials. The optical microscopic work demonstrates how macroscopic control of columnar orientations is achieved by manipulating the LC film thickness, substrate preparation, and the thermal annealing process.
No topic is more fundamental to Chemistry than the nature of the chemical bond. In crystalline solids, the chemical bond gives rise to the electronic bandstructure of the material, this then determines whether the material is a metal, semiconductor, semi-metal, etc.; it determines the optical characteristics, the transport properties and the usefulness of any given crystalline solid. Novel x-ray spectroscopic techniques are now available to probe the electronic structure of crystalline solids, element-by-element and even state-by-state. These synchrotron radiation based methods will be applied to a particular class of crystalline solids to study more fully their basic electronic structure. The electronic structure of a class of crystalline solids will be investigated through a novel application of polarisation dependent synchrotron radiation based resonant soft x-ray emission spectroscopy and x-ray absorption spectroscopies to obtain element specific, symmetry and state selective measurements of ...
Purpose: We have developed a gated spot scanning proton beam therapy system with real-time tumor-tracking. This system has the ability of multiple-gated irradiation in a single synchrotron operation cycle controlling the wait-time for consecutive gate signals during a flat-top phase so that the decrease in irradiation efficiency induced by irregular variation of gate signal is reduced. Our previous studies have shown that a 200 ms wait-time is appropriate to increase the average irradiation efficiency, but the optimal wait-time can vary patient by patient and day by day. In this research, we have developed an evaluation system of the optimal wait-time in each irradiation based on the log data of the real-time-image gated proton beam therapy (RGPT) system. Methods: The developed system consists of logger for operation of RGPT system and software for evaluation of optimal wait-time. The logger records timing of gate on/off, timing and the dose of delivered beam spots, beam energy and timing of ...
Reduction of seed dormancy mechanisms, allowing for rapid germination after planting, is a recurrent trait in domesticated plants, and can often be linked to changes in seed coat structure, in particular thinning. We report evidence for seed coat thinning between 2,000 BC and 1,200 BC, in southern Indian archaeological horsegram (Macrotyloma uniflorum), which it has been possible to document with high precision and non-destructively, through high resolution x-ray computed tomography using a synchrotron. We find that this trait underwent stepped change, from thick to semi-thin to thin seed coats, and that the rate of change was gradual. This is the first time that the rate of evolution of seed coat thinning in a legume crop has been directly documented from archaeological remains, and it contradicts previous predictions that legume domestication occurred through selection of pre-adapted low dormancy phenotypes from the wild.
See first link about a synchrotron projection TV, because we need something like that light-source here, and see the second link about carbon bicarbonate, because it provides the background chemistry that this Idea is about (and sulfur is mentioned in an annotation, too!).. OK, the main problem with making carbon bicarbonate is that the carbon atom is a quite-small atom (significantly smaller than oxygen). I suspect this is the main reason why there is no such thing as poly-CO2 (see link) except under extreme pressure. Therefore, even if we could catalyze the formation of carbon bicarbonate, with its central carbon surrounded by and single-bonded with 4 oxygen atoms, it probably could not be expected to persist.. Sulfur, however, is nicely different. While not as plentiful as carbon, it could be plentiful ENOUGH (see link). Certainly it is routinely extracted from carbon-containing fossil fuels (to mostly prevent acid rain). It is a much larger atom than carbon (significantly larger than ...
Baking the perfect loaf of bread is both a science and an art, so researchers are using Canadas only synchrotron to look at the way bubbles form in bread dough to understand what makes the perfect loaf and how gluten-free ...
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I am a dinosaur enthusiast and have been aware of Noddy for some time, and I find it interesting that you mention the time lapse of the fossil being presented at the Australian Synchrotron. Just wondering, is the fossil still on display there, and is there anywhere that video can be seen? I understand if this was all exclusive, but since I have been interested in this dinosaur for quite some time (I remember Tom and Pat Vickers-Rich bringing it up when they were down at the Otways near Dinosaur Cove, and they mentioned some very intriguing features), I would appreciate it if there is any information I can get from anywhere, or even just any info on when it could become available if it isnt. If you want to reply, just do so on this page and I will check it when I can (no need to rush it or anything ...
A well-preserved dinosaur skeleton from Mongolia unites an unexpected combination of features that defines a new group of semi-aquatic predators related to Velociraptor. Detailed 3-D synchrotron analysis allowed an international team of researchers to present the bizarre 75-million-year-old predator, named Halszkaraptor escuilliei. The study not only describes a new genus and species of bird-like dinosaur that lived in Mongolia but also sheds light on an unexpected amphibious lifestyle for raptorial dinosaurs ...
SLACs meeting facilities also provided a venue for the Homebrew Computer Club and other pioneers of the home computer revolution of the late 1970s and early 1980s. In 1984 the laboratory was named an ASME National Historic Engineering Landmark and an IEEE Milestone.[7]. SLAC developed and, in December 1991, began hosting the first World Wide Web server outside of Europe.[8]. In the early-to-mid 1990s, the Stanford Linear Collider (SLC) investigated the properties of the Z boson using the Stanford Large Detector. As of 2005, SLAC employed over 1,000 people, some 150 of whom were physicists with doctorate degrees, and served over 3,000 visiting researchers yearly, operating particle accelerators for high-energy physics and the Stanford Synchrotron Radiation Laboratory (SSRL) for synchrotron light radiation research, which was indispensable in the research leading to the 2006 Nobel Prize in Chemistry awarded to Stanford Professor Roger D. Kornberg.[9]. In October 2008, the Department of Energy ...
SLACs meeting facilities also provided a venue for the Homebrew Computer Club and other pioneers of the home computer revolution of the late 1970s and early 1980s. In 1984 the laboratory was named an ASME National Historic Engineering Landmark and an IEEE Milestone.[7] SLAC developed and, in December 1991, began hosting the first World Wide Web server outside of Europe.[8] In the early-to-mid 1990s, the Stanford Linear Collider (SLC) investigated the properties of the Z boson using the Stanford Large Detector. As of 2005, SLAC employed over 1,000 people, some 150 of whom were physicists with doctorate degrees, and served over 3,000 visiting researchers yearly, operating particle accelerators for high-energy physics and the Stanford Synchrotron Radiation Laboratory (SSRL) for synchrotron light radiation research, which was indispensable in the research leading to the 2006 Nobel Prize in Chemistry awarded to Stanford Professor Roger D. Kornberg.[9] In October 2008, the Department of Energy ...
TY - JOUR. T1 - The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL. AU - Bergonzi, Celine. AU - Schwab, Michael. AU - Naik, Tanushree. AU - Elias, Mikael H. N1 - Funding Information: This work was supported by the MnDrive Initiative, and BARD grant IS-4960-16 FR to M.E. This work was also prepared by M.E. using federal funds under award NA18OAR4170101 from Minnesota Sea Grant, National Sea Grant College Program, National Oceanic and Atmospheric Administration, U.S. Department of Commerce. The statements, findings, conclusions, and recommendations are those of the authors and do not necessarily reflect the views of NOAA, the Sea Grant College Program or the U.S. Department of Commerce. This paper is journal reprint no. JR659 of the Minnesota Sea Grant College Program. We thank the Advanced Photon Source and beamline staff for access and support (23 ID-B and 23 ID-D). Publisher Copyright: © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, ...
2 adrenergic receptor in complex with its G protein (courtesy of B. Kobilka); ESRF played a major role in the initial GPCR crystal structure determined by the Brian Kobilka Lab, with subsequent structures being obtained with data collected at APS. Top left: an X-ray free-electron laser simulated diffraction pattern with quantum noise for the 70S ribosome (see Tokuhisa et al., pages 899-904). Top right: 2,Fo, - ,Fc, neutron-scattering-length map around the active site of RNase A (see Kusaka et al., pages 994-998). Bottom left: slice through the reconstructed tomographic volume of a cryo-EM/ET observation of an RDV-infected NC24 cell (see Miyazaki et al., pages 826-828). Bottom right: time-of-flight neutron diffraction image of transthyretin recorded by iBIX (Yokoyama et al., pages 834-837). ...
TY - JOUR. T1 - Effects of Cu Precursor Types on the Catalytic Activity of Cu/ZrO2 toward Methanol Synthesis via CO2 Hydrogenation. AU - Tada, Shohei. AU - Oshima, Kazumasa. AU - Noda, Yoshihiro. AU - Kikuchi, Ryuji. AU - Sohmiya, Minoru. AU - Honma, Tetsuo. AU - Satokawa, Shigeo. N1 - Funding Information: This work was supported by the Japan Society for the Promotion of Science (JSPS, nos. 15J10157 and 18K04838) and The Japan Petroleum Institute. The synchrotron radiation experiments were performed at the BL14B2 of SPring-8 with the approval of the Japan Synchrotron Radiation Research Institute (JASRI, proposal no. 2018B1552). We are grateful to Prof. Ken-ichi Shimizu, Dr. Takashi Toyao, and Dr. Kenichi Kon, Hokkaido University, for their kind help with STEM analysis. The authors thank Prof. Hsueh-Ju Liu, National Chiao Tung University, Taiwan, for the discussion about Cu2+ coordination structures. Publisher Copyright: Copyright © 2019 American Chemical Society.. PY - 2019/10/23. Y1 - ...
Electron synchrotrons[edit]. See also: Synchrotron light source. Circular electron accelerators fell somewhat out of favor for ... Synchrotron radiation sources[edit]. Main article: Synchrotron light sources. Some circular accelerators have been built to ... A large number of electron synchrotrons have been built in the past two decades, as part of synchrotron light sources that emit ... Certain accelerators (synchrotrons) are however built specially for producing synchrotron light (X-rays). ...
This technique does not require a synchrotron, yet can produce UV at the edge of the X-ray spectrum. Synchrotron light sources ... X-ray, Synchrotron and Neutron Techniques. 4 (1): 1-11. doi:10.1134/S1027451010010015. ISSN 1027-4510. S2CID 97385151. Archived ... Plasma and synchrotron sources of extreme UV[edit]. Lasers have been used to indirectly generate non-coherent extreme UV (EUV) ...
List of synchrotron radiation facilities T. Hotta (27 October 2009). "Laser Electron Photon Experiment at SPring-8". Osaka ... SPring-8 (an acronym of Super Photon Ring - 8 GeV) is a synchrotron radiation facility located in Sayo Town, Sayo District, ... On its path around the storage ring, the beam passes through insertion devices to produce synchrotron radiation with energies ... Together with the Advanced Photon Source at Argonne National Laboratory and the Cornell High Energy Synchrotron Source at ...
Courant, E. D.; Snyder, H. S. (Jan 1958). "Theory of the alternating-gradient synchrotron" (PDF). Annals of Physics. 3 (1): 1- ... Courant, E. D.; Livingston, M. S.; Snyder, H. S. (1952). "The Strong-Focusing Synchrotron-A New High Energy Accelerator". ... Courant worked at Brookhaven National Laboratory from 1948, first as an associate scientist in the Proton Synchrotron Division ... Chao, A.; Courant, E. (2007). "Spin echo in synchrotrons". Physical Review Special Topics: Accelerators and Beams. 10: 014001. ...
... orbit dynamics of synchrotrons; nuclear reactor physics; electrical propulsion for space; low-energy electron scattering in ...
Synchrotron Rad. 13, 19 (2006) G. Smolentsev and A.V. Soldatov, FitIt: New software to extract structural information on the ...
"History of the Australian Synchrotron". Australian Synchrotron. Archived from the original on 6 July 2009. Retrieved 1 April ... Chief among these are the Australian Synchrotron and CSIRO. The campus is also home to numerous restaurants and retail outlets ... Monash is home to major research facilities, including the Monash Law School, the Australian Synchrotron, the Monash Science ... the Monash University Accident Research Centre and the Monash Centre for Synchrotron Science. Some notable research centres ...
Cosmic ray Health threat from cosmic rays Armed Forces Radiobiology Research Institute Synchrotron Particle therapy "NASA Space ... CS1 maint: discouraged parameter (link) "RHIC , Booster Synchrotron". www.bnl.gov. Retrieved 2020-09-23. "BNL , About NSRL". ... NSRL researchers employ the unique Electron Beam Ion Source (EBIS) and the Alternating Gradient Synchrotron's Booster ...
"Bell's synchrotron team". Archived from the original on 23 July 2011. Retrieved 26 December 2009. "Huntsman Marine Center". ... Some examples include the Canadian Light Source synchrotron (a particle accelerator) in Saskatchewan, Huntsman Marine Science ...
... joined CERN in January 1975 as a Fellow in the Proton Synchrotron division. From 1977 to 1980 he worked at Swiss ... In 1980, he returned to CERN as a staff member in the Proton Synchrotron division, under which he later worked with beam ... This machine created antiprotons for the Super Proton Synchrotron, and was part of the infrastructure that led to the discovery ... "Beam Diagnostics Group". Proton Synchrotron Division. CERN. Archived from the original on 17 June 1997. Retrieved 9 June 2017. ...
Synchrotron light is very well collimated. It is produced by bending relativistic electrons (i.e. those moving at relativistic ... Winick, Herman; Doniach, S (2012). Synchrotron Radiation Research. Springer Science & Business Media. p. 567. ISBN ... Mobilio, Settimio; Boscherini, Federico; Meneghini, Carlo (2014). Synchrotron Radiation: Basics, Methods, and Applications. ...
List of synchrotron radiation facilities European Spallation Source Einfeld, Dieter (2 November 2014). "Multi-bend Achromat ... Coordinates: 55°43′39″N 13°13′59″E / 55.72737°N 13.23298°E / 55.72737; 13.23298 MAX IV is a next-generation synchrotron ... Website of the MAX IV Laboratory Lightsources.org, information about the world's synchrotron and free electron laser light ... Journal of Synchrotron Radiation. 21 (5): 884-903. doi:10.1107/S160057751401666X. ISSN 1600-5775. PMC 4181640. PMID 25177980. E ...
The Wilson Synchrotron Lab, which houses both the Cornell Electron Storage Ring (CESR) and CHESS, is named after Robert R. ... The lab provides synchrotron radiation facilities for multidisciplinary scientific research, with a particular focus on protein ... "Synchrotron radiation sources". Retrieved 2006-06-05. "CHESS Facility Description". Archived from the original on 2006-05-02. ... CLASSE formed from the merger of the Cornell High-Energy Synchrotron Source (CHESS) and the Laboratory for Elementary-Particle ...
The National Synchrotron Light Source operated from 1982 to 2014 and was involved with two Nobel Prize-winning discoveries. It ... Alternating Gradient Synchrotron, a particle accelerator that was used in three of the lab's Nobel prizes. Accelerator Test ... National Synchrotron Light Source II (NSLS-II), Brookhaven's newest user facility, opened in 2015 to replace the National ... "National Synchrotron Light Source". Nsls.bnl.gov. Archived from the original on March 15, 2010. Retrieved March 17, 2010. " ...
"How Synchrotron Works." Brazilian Synchrotron Light Laboratory. CNPEM, n.d. Web. . LNLS. "Sirius Project." Brazilian ... The LNLS has Latin America's only particle accelerator, a synchrotron, used as a synchrotron light source designed and built in ... While not part of Unicamp, the National Synchrotron Light Laboratory (LNLS) is a research institution focused on physics, ... Synchrotron Light Laboratory. CNPEM, n.d. Web. 7 May 2014. . "História , Faculdade de Tecnologia". www.ft.unicamp.br. Retrieved ...
At Cornell, Wilson and his colleagues constructed four electron synchrotrons. The first, a 300 MeV synchrotron, was under ... It is located in what is now known as the Wilson Synchrotron Laboratory. Wilson was one of the first physicists to use Monte ... The last machine he built at Cornell was a 12 GeV synchrotron that remains in use as an injector for the Cornell Electron ... 7-8. "Wilson Synchrotron Laboratory". Cornell University. Retrieved February 16, 2014. "Guide to the Robert R. Wilson Papers, ...
Marinkovic NS, Chance MR (2006-01-01). "Synchrotron infrared microspectroscopy". Reviews in Cell Biology and Molecular Medicine ... July 2014). "Characterization of semiconductor materials using synchrotron radiation-based near-field infrared microscopy and ... "Infrared near-field imaging and spectroscopy based on thermal or synchrotron radiation". Applied Physics Letters. 104 (25): ... "Near-field imaging and nano-Fourier-transform infrared spectroscopy using broadband synchrotron radiation". Optics Express. 21 ...
"Synchrotron Proponents" (PDF). "IUCr". www.iucr.org. Retrieved 2019-08-09. "Academy announces 2016 Fellows , Australian Academy ... She was a proponent of the development plan for use of Crystallographers using the Australian Synchrotron, to create a high- ...
Brookhaven National Laboratory (2004). "Alternating Gradient Synchrotron". U.S. Department of Energy. Brookhaven National ... Tevatron closed 2011 Super Proton Synchrotron, accelerator at CERN used to discover the W and Z bosons Large Electron-Positron ... The idea of using alternating gradient synchrotron (AGS) technology to build storage rings for a proton-proton colliding beam ...
Synchrotron Lab (online). M. Gell-Mann (1964). "A Schematic Model of Baryons and Mesons". Physics Letters. 8 (3): 214-215. ...
"Proton Synchrotron" (PDF). Annual Report. CERN (1959): 47-48. 1960. Retrieved 14 July 2016. "Proton Synchrotron" (PDF). Annual ... Later, the chamber received a 16 GeV/c π− beam from the Proton Synchrotron (PS) enabling the study of pion production in π−- ...
"Synchrotron loses director". 21 August 2012. University, La Trobe. "New appointment for La Trobe". www.latrobe.edu.au. " ... Nugent is a fellow of the Australian Academy of Science (FAA). He sits on the Advisory Board of the Australian Synchrotron. ... In 2011 Nugent was appointed part-time Director of the Australian Synchrotron. He was appointed as Deputy Vice-Chancellor and ... Member of the National Science Advisory Committee of the Australian Synchrotron Member of the Expert Advisory Committee for ...
"The Booster Synchrotron". Argonne National Laboratory. Archived from the original on 24 March 2008. Retrieved 9 January 2008. " ... From the linear accelerator, the electrons are injected into the booster synchrotron. Here, the electrons are sent around an ... The Advanced Photon Source (APS) at Argonne National Laboratory (in Lemont, Illinois, USA) is a national synchrotron-radiation ... Using high-brilliance X-ray beams from the APS, members of the international synchrotron-radiation research community conduct ...
Synchrotron Lab (online). Gell-Mann, M (1962). "Symmetries of baryons and mesons". Physical Review. 125 (3): 1067. Bibcode: ... of Tech., Synchrotron Laboratory. doi:10.2172/4008239. Cite journal requires ,journal= (help) Ne'eman, Y. (August 1961). " ...
ISBN 0-7923-4949-0. Evans, Gwyndaf (October 1994). "The method of Multiple wavelength Anomalous Diffraction using Synchrotron ... Synchrotron Rad. 2, 36-48. E. de la Fortelle and G. Bricogne (1997) "Maximum-Likelihood Heavy-Atom Parameter Refinement for ...
ISBN 0-7923-4949-0. Evans, Gwyndaf (October 1994). "The method of Multiple wavelength Anomalous Diffraction using Synchrotron ... Synchrotron Rad. 2 (Pt 1): 36-48. doi:10.1107/S0909049594006680. PMID 16714785. de la Fortelle E, Bricogne G (1997). Maximum- ...
The uses of synchrotron light sources brought new possibilities for X-ray microscopy in the 1980s. However, as new synchrotron- ... Recently, the use of soft x-rays emitted from laser-produced plasmas rather than synchrotron radiation is becoming more popular ... With this increasing demand for X-ray microscopy in these fields, microscopes based on synchrotron, liquid-metal anode, and ... Sources of soft X-rays suitable for microscopy, such as synchrotron radiation sources, have fairly low brightness of the ...
He and Wilson, who was McDaniel's predecessor as director of LNS, built three more electron synchrotrons of 1 GeV, 2 GeV, and ... CS1 maint: discouraged parameter (link) Feinstein, Matthew (March 6, 1968). "Synchrotron Hits Peak". Cornell Daily Sun. 84 (100 ... McDaniel proposed upgrading the then existing 10 GeV synchrotron with an 8 GeV electron-positron storage ring, which would ... electron synchrotron, one of the first such accelerators in the world. ...
Gürsoy D, De Carlo F, Xiao X, Jacobsen C (2014). "TomoPy: A framework for the analysis of synchrotron tomographic data". ... Journal of Synchrotron Radiation. 21 (5): 1188-1193. doi:10.1107/S1600577514013939. PMC 4181643. PMID 25178011. Toby HB, Gürsoy ... Synchrotron Radiation News. 28 (2): 15-21. doi:10.1080/08940886.2015.1013415. S2CID 121506989.. ...
Dedicated or partially dedicated GISAXS beamlines exist at many synchrotron light sources (for instance SSRL, APS, CHESS, ESRF ... Synchrotron Radiation News. Informa UK Limited. 15 (5): 35-42. doi:10.1080/08940880208602975. ISSN 0894-0886. S2CID 122797468. ...
Synchrotron Light Sources of the World. *A Miniature Synchrotron: room-size synchrotron offers scientists a new way to perform ... As part of synchrotron light sources[edit]. See also: List of synchrotron radiation facilities ... The first synchrotron to use the "racetrack" design with straight sections, a 300 MeV electron synchrotron at University of ... Synchrotron radiation also has a wide range of applications (see synchrotron light) and many 2nd and 3rd generation ...
The Proton Synchrotron Booster (PSB), a synchrotron, is the first and smallest circular proton accelerator in the accelerator ... Before the PSB was built in 1972, LINAC 2 injected directly into the Proton Synchrotron, but the greater injection energy ... ready to be injected into the Proton Synchrotron. ...
Synchrotron, cyclic particle accelerator in which a charged particle-generally, a subatomic particle, such as an electron or a ... Electron synchrotrons are also used to produce synchrotron radiation. Heavy-ion synchrotrons are used primarily in nuclear ... particle accelerator: Synchrotrons. As the particles in a synchrotron are accelerated, the strength of the magnetic field is ... particle accelerator: Synchrotrons. As the particles in a synchrotron are accelerated, the strength of the magnetic field is ...
In particle accelerator: Proton synchrotrons. …by the cost of the magnet ring, which increases only as the first power of the ...
"Australian Synchrotron: 2015 Annual Report" (PDF). Australian Synchrotron. Retrieved 23 March 2016. "Synchrotron light to shine ... ANSTOs Australian Synchrotron is a 3 GeV national synchrotron radiation facility located in Clayton, in the south-eastern ... Australian Nuclear Science and Technology Organisation "Australian Synchrotron Machine Fact sheet". Australian Synchrotron ... website about the worlds synchrotrons The Australian Synchrotron is great... but what does it do? at The Conversation, March ...
The Diamond synchrotron in Oxfordshire, England can produce a light that is 10 billion times greater than the sun. Read about ... And like other synchrotrons, the Diamond synchrotron will be used for more than reading ancient texts. The synchrotrons ... For links to information about the worlds synchrotrons and to learn more about synchrotrons and other powerful light sources, ... There are several dozen synchrotrons around the world. Like the Diamond synchrotron, they act as incredibly powerful ...
It describes the basic concepts and the essential challenges for the development of compact synchrotron radiation sources from ... Compact Synchrotron Light Sources. Volume 3 of Series on synchrotron radiation techniques and applications. Volume 3 of World ... structure superconducting compact superconducting magnets symmetry synchrotron light synchrotron light sources synchrotron ... It describes the basic concepts and the essential challenges for the development of compact synchrotron radiation sources from ...
Therefore, we are organising a Metallurgy with Synchrotrons workshop that will take place on December 6th and 7th 2010 at the ... European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France. ... dedicated to research in metallurgy and materials science using synchrotron radiation. In this context of proposed French ...
It is one of only eight synchrotrons in the US and the only state-funded facility. ... Materials Characterization with Synchrotron Radiations. The Center for Advanced Microstructures and Devices (CAMD) is the ... It is one of only eight synchrotrons in the US and the only state-funded facility. Employing eight bending magnets and ... This dual-degree program welcomes new graduate students to participate in synchrotron-based experimental research. ...
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One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOEs Office of Science by Brookhaven Science Associates, a limited-liability company founded by the Research Foundation for the State University of New York on behalf of Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit applied science and technology organization.. Site Index , Privacy and Security Notice , Report a Problem With This Page ...
The main difference between synchrotron light and the X-rays used in hospitals is the brilliance: a synchrotron source is one ... The ESRF produces synchrotron light with wavelengths ranging from gamma rays to infrared radiation. It consists mostly of X- ... The synchrotron X-ray beam can have other valuable properties, including time structure (so that it flashes), coherence (making ... European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France. ...
The Layout of X-Ray Optics and Instruments for the Use of Synchrotron Radiation at the Outstation of the European Molecular ... Protein Crystallography with Synchrotron Radiation I. General Discussion and High Resolution Data Collection ... Protein Crystallography with Synchrotron Radiation II. Anomalous Scattering and the Phase Problem ... experiment fluorescence lead microscopy molecular biology polarization spectroscopy structure synchrotron synchrotron radiation ...
Our photo gallery takes you inside the Synchrotron, Australias only particle accelerator that creates high-intensity light for ... A diagram of the synchrotron. The synchrotron uses two particle accelerator rings to bring electrons to 99.9 per cent of the ... The Australian Synchrotron is one of several particle accelerators located around the world, part of a family that includes the ... Currently, the synchrotron distributes its data to the scientific community via AARNet. However, in the future they are looking ...
Hendrickson WA (2000) Synchrotron crystallography. Trends Biochem Sci 25:637-643PubMedCrossRefGoogle Scholar ... Serial synchrotron crystallography (SSX) Microcrystal Lipidic cubic phase (LCP) In meso in situ Room temperature (RT) Cryogenic ... Botha S, Nass K, Barends TRM et al (2015) Room-temperature serial crystallography at synchrotron X-ray sources using slowly ... Gati C, Bourenkov G, Klinge M et al (2014) Serial crystallography on in vivo grown microcrystals using synchrotron radiation. ...
Pioneering synchrotron science. ESRF-EBS, the first of a new generation of high-energy synchrotron sources, opens up new ... European Synchrotron. RT @esrfsynchrotron: Check the @esrfsynchrotron twitter #Fleet 🔝 to have a look to the Q&A with Marine ... European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France. ... ESRF-EBS, the worlds brightest synchrotron, provides the international scientific community with unprecedented tools to study ...
Synchrotron radiation plays a leading role in pure science and in emerging technologies. The Journal of Synchrotron Radiation ... Synchrotron radiation research is rapidly expanding with many new sources of radiation being created globally. ... provides comprehensive coverage of the entire field of synchrotron radiation and free-electron laser research including ...
Synchrotron Projection TV Synchrotron_20Projection_20TV. As mentioned in the main text. [Vernon, Aug 13 2011] Carbon ... Synchrotron Catalyzed Sulfur BiCarbonate. Just the right nudges, and lock 6 CO2 molecules to 1 sulfur atom. (0) [vote for,. ... See first link about a synchrotron projection TV, because we need something like that light-source here, and see the second ... We may need 6 different frequencies of light, one for each segment --the synchrotron can be 6-sided, of course-- and light ...
Pioneering synchrotron science. ESRF-EBS, the first of a new generation of high-energy synchrotron sources, opens up new ... European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France. ... ESRF-EBS, the worlds brightest synchrotron, provides the international scientific community with unprecedented tools to study ...
Synchrotron radiation microtomography is now routinely used on several beamlines to perform investigations on a wide range of ... European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France. ... The ESRF is the place where the most significant progress of the relatively young synchrotron radiation microtomography ...
cation of high energy synchrotron radiation in condensed matter research. In 1993 he became head of the synchrotron radiation ... The theory of synchrotron radiation and of the freeelectron laser, design examples and the technology basis are presented. The ... Synchrotron Light Sources and Free-Electron Lasers. Accelerator Physics, Instrumentation and Science Applications. Editors: ... In his tenure at the National Synchrotron Light Source the NSLS R&D effort developed many of the methods and instruments in ...
... and the Cornell High Energy Synchrotron to confirm the hypothesis of a poly (rA) double-helix. The detailed 3D structure of ... is Canadas national centre for synchrotron research. CLS operations are funded by the Canada Foundation for Innovation, the ...
Synchrotron sheds new light on research questions. Becky Rynor. CMAJ September 08, 2015 187 (12) E367; DOI: https://doi.org/ ...
... is to promote the utilization of synchrotron techniques to perform cutting-edge catalysis nano-science research under in-situ ... SCC mission The purpose of the Synchrotron Catalysis Consortium (SCC) ... Synchrotron Catalysis Consortium (SCC) SCC mission. The purpose of the Synchrotron Catalysis Consortium (SCC) is to promote the ... The beamlines (X18B, X19A and X18A) and facilities are located in the National Synchrotron Light Source (NSLS) at Brookhaven ...
Using synchrotron light to produce 3D images The properties of synchrotron light are also of benefit in synchrotron tomography ... Synchrotron light Matter and Material Research Using Synchrotron Light Materials Research zoom ... At PSI, synchrotron light is generated in the Swiss Light Source SLS. Synchroton light is exceptionally intense Synchrotron ... Synchrotron light has flexible properties The properties of synchrotron light can be precisely adapted to suit the requirements ...
The biological effects of synchrotron microbeam radiation therapy on normal and tumour tissues Lead researcher. Prof Peter ...
... at the SLAC National Accelerator Laboratory is a national synchrotron x-ray research facility funded by the U.S. Department of ...
Tag: synchrotron radiation analysis. Posted on March 21, 2013. January 3, 2016. ... Followup work with μct-scanning and synchrotron radiation analysis reveals that the sensory structures (like rod or cone outer ...
  • Therefore, we are organising a Metallurgy with Synchrotrons workshop that will take place on December 6th and 7th 2010 at the ESRF. (esrf.eu)
  • The ESRF produces synchrotron light with wavelengths ranging from gamma rays to infrared radiation. (esrf.fr)
  • ESRF-EBS, the world's brightest synchrotron, provides the international scientific community with unprecedented tools to study materials and living matter. (esrf.fr)
  • ESRF-EBS, the first of a new generation of high-energy synchrotron sources, opens up new opportunities in X-ray science. (esrf.fr)
  • The ESRF is the place where the most significant progress of the relatively young synchrotron radiation microtomography technique has been achieved. (esrf.eu)
  • In 2007, she worked as a visiting scientist at the European Synchrotron Radiation Facility (ESRF), Grenoble, France, in both the Macromolecular Crystallography group and the Soft Condensed Matter group. (routledge.com)
  • When I was looking for a job abroad after returning from Erasmus, I heard about the ESRF (European Synchrotron Radiation Facility) , the biggest synchrotron in Europe. (kde.org)
  • Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working on a metallorganic molecule as an antitumor drug. (bionity.com)
  • The brightest red fluorescent protein ever, mScarlet, has just been engineered by researchers at the University of Amsterdam, the Institut de Biologie Structurale, IBS (CEA/CNRS/University Grenoble Alpes) and the European Synchrotron (ESRF) in France. (bionity.com)
  • In this work, the complementarity of pump-probe experiments at SwissFEL (ALVRA endstation) and at synchrotrons (SuperXAS beamline of SLS and ID09 of ESRF) is used to investigate the triplet excited state of Cu OLED materials. (psi.ch)
  • The ESRF uses synchrotron radiation emitted as a result of electrons being accelerated around a storage ring housed in the circular building seen in the picture. (sciencephoto.com)
  • Dr. Brenker and colleagues used a highly focussed x-ray beam at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. (berkeley.edu)
  • The instrument was delivered in August 2006 and successfully passed the acceptance tests using the synchrotron radiation of the ID08 beamline at the ESRF and subsequently with the laboratory Hg, D2 and Al Kα sources at MINATEC. (cea.fr)
  • This thesis summarises experimental results on the molecular spectroscopy of gas phase molecules excited by synchrotron radiation in the VUV and soft X-ray regions. (dissertations.se)
  • The Journal of Synchrotron Radiation provides comprehensive coverage of the entire field of synchrotron radiation and free-electron laser research including instrumentation, theory, computing and scientific applications in areas such as biology, nanoscience and materials science. (iucr.org)
  • Peiqiang Yu, " Microprobing the molecular spatial distribution and structural architecture of feed-type sorghum seed tissue ( Sorghum Bicolor L. ) using the synchrotron radiation infrared microspectroscopy technique ," Journal of Synchrotron Radiation , vol. 18, no. 5, pp. 790-801, 2011. (hindawi.com)
  • The interior of the Australian Synchrotron facility, a synchrotron light source . (wikipedia.org)
  • ANSTO's Australian Synchrotron is a 3 GeV national synchrotron radiation facility located in Clayton, in the south-eastern suburbs of Melbourne, Victoria, which opened in 2007. (wikipedia.org)
  • ANSTO's Australian Synchrotron is a light source facility (in contrast to a collider), which uses particle accelerators to produce a beam of high energy electrons that are boosted to nearly the speed of light and directed into a storage ring where they circulate for many hours or even days at a time. (wikipedia.org)
  • ANSTO's Australian Synchrotron supports the research needs of Australia's major universities and research centres, and businesses ranging from small-to-medium enterprises to multinational companies. (wikipedia.org)
  • During 2014-15 the Australian Synchrotron supported more than 4,300 researcher visits and close to 1,000 experiments in areas such as medicine, agriculture, environment, defence, transport, advanced manufacturing and mining. (wikipedia.org)
  • Each dipole magnet is a potential source of synchrotron light and most straight sections can also host an insertion device, giving the possibility of 30+ beamlines at the Australian Synchrotron. (wikipedia.org)
  • The Australian Synchrotron is one of several particle accelerators located around the world, part of a family that includes the Large Hadron Collider at the European Organization for Nuclear Research ( CERN ). (zdnet.com)
  • Think of the electrons as a surfboard on a wave," explained Richard Farnsworth, head of controls and IT at the Australian synchrotron. (zdnet.com)
  • The Australian Synchrotron is a major research facility located in Clayton, a technology and innovation hub of southeast Melbourne. (ansto.gov.au)
  • The Australian Synchrotron produces powerful beams of light that are used at individual experimental facilities to examine the molecular and atomic details of a wide range of materials. (ansto.gov.au)
  • In June 2006, the Australian Synchrotron project reached a major milestone with engineers and scientists achieving 'first light', confirming that the machine was working as planned. (ansto.gov.au)
  • Since commencing operations in 2007 the Australian Synchrotron has demonstrated that it is arguably one of the most successful scientific user facilities, bringing benefits to over 5000 researchers a year from academia, medical research institutes, government and other research organisations and industry. (ansto.gov.au)
  • In 2013 ANSTO became the new operator of the Australian Synchrotron, which brought together two of the nation's most significant pieces of scientific infrastructure to advance science outcomes for the nation. (ansto.gov.au)
  • Through Project BR - GHT, ANSTO has, to date, secured $80.2 million in new funding to expand the research capabilities of the Australian Synchrotron over the next decade. (ansto.gov.au)
  • Leonie's insights into crystallisation processes could significantly help the development of treatments for a variety of illnesses," said Australian Synchrotron Director, Professor Andrew Peele. (lightsources.org)
  • The Diamond synchrotron was initially constructed with seven beamlines, though many more could be added. (howstuffworks.com)
  • Farnsworth says as many as 20 beamlines can be split off the synchrotron to be used for experimentation. (zdnet.com)
  • Synchrotron radiation microtomography is now routinely used on several beamlines to perform investigations on a wide range of topics. (esrf.eu)
  • The beamlines (X18B, X19A and X18A) and facilities are located in the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratories. (yu.edu)
  • One of the main points will be to understand what the requirements of the UAE scientists are in terms of synchrotron research (what types of beamlines, techniques, etc. (iucr.org)
  • The synchrotron produces X-ray and infrared radiation that is channelled down long pipelines, known as beamlines, into a suite of scientific instruments. (ansto.gov.au)
  • Fifty years later, scientists from McGill University successfully crystallized a short RNA sequence, poly (rA)11, and used data collected at the Canadian Light Source (CLS) and the Cornell High Energy Synchrotron to confirm the hypothesis of a poly (rA) double-helix. (mcgill.ca)
  • Recently SINTEF and UOP, a leading international supplier of catalysts, installed a test system for controlling the gas and liquid feed for in situ catalyst studies using high-energy synchrotron X-rays at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). (sintef.no)
  • The straight sections along the closed path in such facilities are not only required for radio frequency cavities, but also for particle detectors (in colliders) and photon generation devices such as wigglers and undulators (in third generation synchrotron light sources). (wikipedia.org)
  • Measuring, processing, and merging many partial data sets of this kind requires new techniques which have since been implemented at several third-generation synchrotron facilities, and are described here. (springer.com)
  • He was project director of the construction of BESSY II, the first German third-generation synchrotron light source. (springer.com)
  • ALBA is a third-generation synchrotron radiation facility in the Barcelona Synchrotron Park, in Cerdanyola del Vallès, Spain. (kde.org)
  • The properties of synchrotron light are also of benefit in synchrotron tomography. (psi.ch)
  • The objects investigated by synchrotron tomography range from engineering materials to rocks to biological tissue - and even to archaeological finds. (psi.ch)
  • This paper discusses the results of recent experiments at Stanford Synchrotron Radiation Laboratory (SSRL) and Hamburger Synchrotronstrahlungslabor (HASYLAB) which were designed to explore the feasibility of using synchrotron radiation in high-resolution, computerized, critical-absorption tomography. (unt.edu)
  • Here we present, to our knowledge, the first phase-contrast tomography acquired at a compact light source, a recently developed compact synchrotron based on inverse Compton scattering. (pnas.org)
  • A prospective, observational study was conducted at the Canadian Light Source to compare ovarian imaging ex vivo using propagation-based computed tomography (PB-CT) synchrotron imaging, ultrasonography , and histology. (omicsonline.org)
  • The effectiveness of Talbot grating interferometry computed tomography (TGI-CT) synchrotron imaging to image preserved bovine (n=1) and human (n=1) ovaries was evaluated at the SPring-8 synchrotron, Japan. (omicsonline.org)
  • We report evidence for seed coat thinning between 2,000 BC and 1,200 BC, in southern Indian archaeological horsegram ( Macrotyloma uniflorum ), which it has been possible to document with high precision and non-destructively, through high resolution x-ray computed tomography using a synchrotron. (nature.com)
  • Complementing this, other techniques for examining larger specimens or to avoid sectioning "difficult" material include neutron imaging, nuclear magnetic resonance (NMR) imaging, X-ray computed tomography (CT), high-resolution X-ray computed tomography (HRCT), and synchrotron radiation X-ray tomographic microscopy (SRXTM). (pnas.org)
  • Protein Crystallography with Synchrotron Radiation II. (springer.com)
  • At the time of the picture, the synchrotron was being used for experiments including protein crystallography and x-ray adsorption spectroscopy. (zdnet.com)
  • Hendrickson WA (2000) Synchrotron crystallography. (springer.com)
  • The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics, coherent X-Ray diffraction, and laser cutting and contactless sample manipulation are described in details. (routledge.com)
  • The development of serial crystallography methods at X-ray free-electron lasers and subsequently at synchrotron light sources allows new approaches to tackle this challenge. (iucr.org)
  • Here we compare the conformational ensembles of CypA by multitemperature synchrotron crystallography and fixed-target X-ray free-electron laser (XFEL) crystallography. (rcsb.org)
  • ESCA celebrate the International Year of Crystallography by organizing The 12th International Workshop on Synchrotron Radiation in Nanomaterials Research. (iucr.org)
  • A partnership between major French metallurgical groups and academic partners is aiming to take advantage of funding initiatives currently on offer from the French government which could finance a facility (high energy beamline) dedicated to research in metallurgy and materials science using synchrotron radiation. (esrf.eu)
  • Two scientists hard at work on infra-red spectroscopy using a beamline from the synchrotron. (zdnet.com)
  • The project involved nearly 70 scientists and clinicians from 9 European countries, including all synchrotron facilities that have or are planning an infrared beamline. (rsc.org)
  • Synchrotron beamline for experiments within an energy range hv = 80-150 eV. (fz-juelich.de)
  • In addition, perspectives on the impact of synchrotron based applications, particularly X-ray absorption spectroscopy, and the role of synchrotron applications in remediation, regulatory, and decision making processes are considered. (elsevier.com)
  • Synchrotron Based FTIR Spectroscopy in Lung Cancer. (rsc.org)
  • The book focuses specifically on biomedical IR spectroscopy using synchrotron light sources with particular emphasis on understandable presentation of necessary background knowledge, digestible summaries of research progress and above all as a practical 'how to do it' guide for those working in or wishing to enter the field of biomedical synchrotron IR microspectroscopy and imaging. (rsc.org)
  • Synchrotron based micro X-ray Absorption Spectroscopy was used to obtain micro scale chemical information such as coordination and oxidation state of phases constituting corrosion products within archaeological iron artefacts buried in soil. (cea.fr)
  • RIKEN and the Japan Synchrotron Radiation Research Institute (JASRI) have successfully produced a first beam of X-ray laser light with a wavelength of 1.2 Angstroms. (phys.org)
  • Construction workers and scientists mix together on the synchrotron floor. (zdnet.com)
  • The purpose of the workshop is to bring together the best scientists from the United Arab Emirates (UAE) and synchrotron experts and see how the most strategic fields for the UAE can be addressed through synchrotron science. (iucr.org)
  • Starting October 29th, the scientists will now be able to use the world's first mini synchrotron for high-brilliance X-rays at their institute. (news-medical.net)
  • Synchrotron light is millions of times brighter than the surface of the Sun, which allows scientists to visualize atomic structures in extremely high resolutions. (kde.org)
  • Thirty years ago, SSRL was among the first laboratories in the world to use synchrotron produced x-rays for studying matter at atomic and molecular scales, and the first to offer beam time to a broad user community of scientists from academic, industry and government labs (based on peer-reviewed proposals). (innovations-report.com)
  • Scientists from Finland and France have developed a new synchrotron X-ray technique that may revolutionize the chemical analysis of rare materials like meteoric rock samples or fossils. (bionity.com)
  • Diamond Light Source - the giant Oxfordshire synchrotron that uses beams of extremely bright light to probe the properties of everything from fossils to jet engines - is being used by a team of international scientists to probe rock samples recovered during the Apollo missions, nearly 50 years ago. (theengineer.co.uk)
  • An international collaboration between scientists from the Brazilian Synchrotron Light Laboratory (LNLS) and the University of Colorado, Boulder (CU-Boulder) brings new understanding on fundamentals of infrared interferometry for scattering-type Scanning Near-Field Optical Microscopy (s-SNOM). (lightsources.org)
  • This article is about the synchrotron, a particle accelerator . (wikipedia.org)
  • For applications of the synchrotron radiation produced by cyclic particle accelerators, see synchrotron light source . (wikipedia.org)
  • A synchrotron is a particular type of cyclic particle accelerator , descended from the cyclotron , in which the accelerating particle beam travels around a fixed closed-loop path. (wikipedia.org)
  • The most powerful modern particle accelerators use versions of the synchrotron design. (wikipedia.org)
  • The largest synchrotron-type accelerator, also the largest particle accelerator in the world, is the 27-kilometre-circumference (17 mi) Large Hadron Collider (LHC) near Geneva, Switzerland, built in 2008 by the European Organization for Nuclear Research (CERN). (wikipedia.org)
  • The synchrotron evolved from the cyclotron , the first cyclic particle accelerator. (wikipedia.org)
  • Synchrotron , cyclic particle accelerator in which a charged particle-generally, a subatomic particle , such as an electron or a proton , or a heavy-ion particle, such as a gold ion-is accelerated to very high energies in the presence of an alternating electric field while confined to a constant circular orbit by a magnetic field . (britannica.com)
  • The synchrotron is useful when the particle is accelerated to a speed approaching the speed of light-as in the acceleration of electrons or protons to extremely high energies-since, under such conditions, speed changes only slowly as the energy changes. (britannica.com)
  • The highest-energy particle accelerators yet built are proton synchrotrons. (britannica.com)
  • The synchrotron uses two particle accelerator rings to bring electrons to 99.9 per cent of the speed of light. (zdnet.com)
  • For some years now it has been possible to generate high-brilliance X-rays using ring-shaped particle accelerators (synchrotron sources). (news-medical.net)
  • Meera - Hello, this week I'm at Diamond Light-Source out at Didcot, Oxfordshire to find out about the giant particle accelerator located out here known as the synchrotron. (thenakedscientists.com)
  • The original SPEAR ring, built for particle physics programs at SLAC, yielded two Nobel prizes as well as fertile ground for innovating synchrotron techniques and making important discoveries. (innovations-report.com)
  • Synchrotron radiation laboratories are large scientific facilities where various scientific experiments are carried out by the use of radiation produced by particle accelerators. (dissertations.se)
  • Research with synchrotron radiation emerged in the 1960s and 1970s as a peripheral activity at particle physics laboratories. (dissertations.se)
  • This gap could be closed by laser-driven compact synchrotron light sources (CLS), which use an infrared (IR) laser cavity in combination with a small electron storage ring. (pnas.org)
  • The reader sees the eleborate production and remarkable properties of synchrotron radiation unfolded withinmerely 251 pages and 15 chapters. (indigo.ca)
  • The Stanford Synchrotron Radiation Lightsource at SLAC National Accelerator Laboratory produces extremely bright x-rays used to study our world at the atomic and molecular level, leading to major advances in energy production, environmental remediation, nanotechnology, new materials and medicine. (lightsources.org)
  • The Stanford Synchrotron Radiation Lightsource is an Office of Science User Facility operated for the Department of Energy by Stanford University. (lightsources.org)
  • Common core structure of amyloid fibrils by synchrotron X-ray diffraction. (nih.gov)
  • Using intense synchrotron sources we observed that six different ex vivo amyloid fibrils and two synthetic fibril preparations all gave similar high-resolution X-ray fibre diffraction patterns, consistent with a helical array of beta-sheets parallel to the fibre long axis, with the strands perpendicular to this axis. (nih.gov)
  • The diffraction-before-destruction nature of XFEL experiments provides a radiation-damage-free view of the functionally important alternative conformations of CypA, confirming earlier synchrotron-based results. (rcsb.org)
  • X‐ray diffraction with intense synchrotron radiation has demonstrated a structural basis for the molecular mechanism underlying muscle contraction with high spatial‐ and time‐resolution. (els.net)
  • The structural alterations in vertebrate skeletal muscles undergoing contraction by synchrotron X‐ray diffraction are outlined by putting a lot of weight on the thin filament as the locus of actomyosin interaction. (els.net)
  • The article "Local structure of ion pair interaction in lapatinib amorphous dispersions characterized by synchrotron X-ray diffraction and pair distribution function analysis" (doi: 10.1038/srep46367) by Gabriel L. B. de Araujo, Chris J. Benmore and Stephen R. Byrn can be read in Scientific Reports at nature.com/articles/srep46367. (dicyt.com)
  • Real-time temperature dependence of X-ray diffraction patterns for nylons 65 and 56 was studied by synchrotron radiation to gain understanding of the Brill transition usually occurring in polyamides. (upc.edu)
  • While the synchrotron is online and currently being used for experiments, several parts of it are still being built. (zdnet.com)
  • The properties of synchrotron light can be precisely adapted to suit the requirements of individual experiments. (psi.ch)
  • Experiments with these probes often complement investigations with synchrotron light. (psi.ch)
  • It is this electromagnetic energy, called synchrotron light that we use in the experiments. (thenakedscientists.com)
  • It's the small size of the electron beam that gives rise to very bright synchrotron light that we want to generate and use in our experiments. (thenakedscientists.com)
  • Students will conduct short experiments at Argonne's Advanced Photon Source and at Oak Ridge National Laboratory's Spallation Neutron Source and High Flux Isotope Reactor, which provides hands-on experience using neutron and synchrotron sources. (conference-service.com)
  • Experiments with synchrotron light offer several advantages over conventional techniques in terms of accuracy, quality, robustness and the level of detail that can be seen and collected, and are much faster than traditional methods. (ansto.gov.au)
  • The researchers have already used the results of their experiments at the Synchrotron to improve the design of future fuel cells. (minatec.org)
  • Then there's the U of S campus, which houses not only the Saskatchewan Structural Sciences Centre (SSSC), which houses the NMR instruments necessary to study organic phosphorus, but also the Canadian Light Source Synchrotron (CLS), which enables the team to study key inorganic phosphates in unprecedented detail. (lightsource.ca)
  • High resolution synchrotron microtomography capable of revealing microvessels in three dimensional (3D) establishes distinct imaging markers of mouse kidney disease strongly associated to renal tubulointerstitial (TI) lesions and glomerulopathy. (nature.com)
  • Recent progress in synchrotron X-ray microtomography technology has caused a revolution in imaging methods used to study the dermal skeletons of early vertebrates. (diva-portal.org)
  • For links to information about the world's synchrotrons and to learn more about synchrotrons and other powerful light sources, please check out the links below. (howstuffworks.com)
  • The purpose of the Synchrotron Catalysis Consortium (SCC) is to promote the utilization of synchrotron techniques to perform cutting-edge catalysis nano-science research under in-situ conditions. (yu.edu)
  • In the present work, six of them have been selected to be studied by in situ synchrotron X-ray thermodiffraction. (mdpi.com)
  • The objective of this study is to determine whether the synchrotron can be used to effectively image bovine and human ovaries ex situ. (clinicaltrials.gov)
  • The objective of our research is to determine whether the synchrotron is an effective tool for imaging human ovaries ex situ. (clinicaltrials.gov)
  • We believe that synchrotron imaging of human ovaries ex situ will be an important first step to develop future high-resolution tools for imaging reproductive tissues in situ. (clinicaltrials.gov)
  • This is the first in vitro and time-resolved investigation of enamel demineralisation using synchrotron X-ray techniques which allows in situ quantification of the microstructure evolution over time in a simulated carious lesion. (unboundmedicine.com)
  • This review completely summarizes the in situ synchrotron X-ray techniques emerged in the recent years for real-time probing nanophase evolution of colloidal nanoparticles. (wiley.com)
  • The success of this approach shows the potential for high-throughput drug screening and even structural enzymology on short timescales at bright synchrotron light sources. (iucr.org)
  • In June 2001, the Victorian Government announced its decision to build a national synchrotron facility on land adjacent to Monash University. (ansto.gov.au)
  • The synchrotron is one of the first accelerator concepts to enable the construction of large-scale facilities, since bending, beam focusing and acceleration can be separated into different components. (wikipedia.org)
  • The booster is an electron synchrotron which takes the 100 MeV beam from the linac and increases its energy to 3 GeV. (wikipedia.org)
  • Two of the straight sections are used to host the storage ring 500 MHz RF cavities, which are essential for replacing the energy that the beam loses through synchrotron radiation. (wikipedia.org)
  • The process begins with an electron gun that shoots a beam of electrons down a straight tube, called the linac , which accelerates the electrons before sending them into the circular booster synchrotron . (howstuffworks.com)
  • The synchrotron X-ray beam can have other valuable properties, including time structure (so that it flashes), coherence (making it a parallel beam) and polarization. (esrf.fr)
  • This display shows the status of the synchrotron beam. (zdnet.com)
  • Between X-ray tubes and large-scale synchrotron sources, a large gap in performance exists with respect to the monochromaticity and brilliance of the X-ray beam. (pnas.org)
  • Meera - So now I know how the synchrotron actually runs, but what benefit does this high beam of light actually provide? (thenakedscientists.com)
  • Moreover, a conventional laser facility (c.w. and pulsed), as well as the possibility of combining high intensity/high repetition rate (1 mJ/100 kHZ, 5 mJ/20 kHZ, 10 mJ/10 kHZ) femtosecond laser pulses from an in-house facility to the synchrotron beam in pump-probe schemes will also be offered to the users in the near future. (synchrotron-soleil.fr)
  • Behaviour of the electron beam in a synchrotron radiation storage ring. (indigo.ca)
  • Modern, third-generation synchrotrons make use of hard X-rays, a monochromatic beam, and a high beam intensity to scan specimens. (pnas.org)
  • It can produce an X-ray monochromatic beam with energy up to 25 keV and an intensity greater than 10 orders of the intensity of synchrotron radiation on the most powerful source of such radiation-the SPring-8 Storage Ring in Japan. (phys.org)
  • The figure above depicts the s-SNOM setup used in the published work using two different sources, a tunable narrow band quantum cascade laser (QCL) and the synchrotron broadband IR beam. (lightsources.org)
  • Synchrotron light sources in their entirety are sometimes called "synchrotrons", although this is technically incorrect. (wikipedia.org)
  • citation needed] The combination of time-dependent guiding magnetic fields and the strong focusing principle enabled the design and operation of modern large-scale accelerator facilities like colliders and synchrotron light sources. (wikipedia.org)
  • It describes the basic concepts and the essential challenges for the development of compact synchrotron radiation sources from an accelerator designer's point of view and gives an outline of the actual state of the art. (google.com)
  • Synchrotron radiation research is rapidly expanding with many new sources of radiation being created globally. (iucr.org)
  • Developing new radiation sources with higher brilliance and much extended spectral range resulted in stunning developments like the electron synchrotron and electron storage ring and the freeelectron laser. (springer.com)
  • The 20th century was dedicated to the development and improvement of synchrotron light sources with an ever ongoing increase of brilliance. (springer.com)
  • The test system was constructed in the Department of Process intensification and Catalysis at SINTEF Materials and Chemistry in Oslo, and represents the latest in a series of development projects within a SINTEF/UOP alliance during the last 15 years, and builds on UOP's 20+ year experience of using synchrotron light sources. (sintef.no)
  • Aujourd'hui, les anneaux synchrotrons, tels que l'ESRF à Grenoble ou le synchrotron SOLEIL sur le plateau de Saclay, sont des sources intenses de photons (de l'infra-rouge aux rayons X). De nombreuses équipes de l'IRAMIS réalisent régulièrement des expériences autour de ces sources. (cea.fr)
  • SPEAR3 incorporates the latest technology-much of it pioneered at SSRL and SLAC-to make it competitive with the best synchrotron sources in the world. (innovations-report.com)
  • Synchrotron light sources are powerful facilities that produce light in a variety of "colors," or wavelengths-from the infrared to X-rays-by accelerating electrons to emit light in controlled beams. (phys.org)
  • The second class of techniques exploits the high lateral coherence of modern synchrotron sources, a byproduct of the quest for high brightness or brilliance. (mdpi.com)
  • Synchrotron radiation sources have greatly contributed to the progress in many fields of science. (dissertations.se)
  • In the last few decades, the use of ultra-bright IR light sources, such as synchrotrons and lasers, has improved dramatically the signal-to-noise ratio (SNR) of FTIR and consequently has increased sensitivity. (lightsources.org)
  • The study, published in Scientific Reports, used high-energy X-rays generated by synchrotron light sources at Argonne National Laboratory near Chicago in the United States. (dicyt.com)
  • The instrument is also unique in the world because it can operate with both synchrotron radiation sources and laboratory sources. (cea.fr)
  • In the week of April 1-5 PSI welcomes 20 PhD students and postdocs taking part in the European HERCULES 2019 school on Neutron and Synchrotron Radiation. (psi.ch)
  • This thesis will be conducted in the framework of a collaboration between CEA Saclay and the SOLEIL synchrotron and Pierre and Marie Curie University. (synchrotron-soleil.fr)
  • This thesis is co-financed by the Synchrotron SOLEIL and the National Research Agency, within the framework of the project ANR-17-CE30-0017-HighEneCh. (synchrotron-soleil.fr)
  • Publication of a multi-author textbook on the biomedical applications of synchrotron infrared microspectroscopy was a central element in the workplan of the EU project DASIM (Diagnostic Applications of Synchrotron Infrared Microspectroscopy). (rsc.org)
  • The field of biomedical applications of synchrotron IR microspectroscopy, which has recently seen unprecedented growth, is extremely interdisciplinary, involving synchrotron physicists, spectroscopists, biologists and clinicians, with associated difficulties in getting these experts to understand each other. (rsc.org)
  • Based on lectures presented at the Fourth International Conference on Biophysics and Synchrotron Radiation (1992), this book cogently presents up-to-the-minute reviews and progress reports on the latest applications of synchrotron radiation to bioscience, biophysical, and medical research. (valorebooks.com)
  • The extraordinary and unique characteristics of synchrotron radiation--its brightness, collimation, and unlimited tunability--have opened up tremendous opportunities for the biosciences, most notably in the study of the structures, functions, and dynamics of biological objects. (valorebooks.com)
  • The advanced characteristics of synchrotron light has led in recent years to the development of a series of new experimental techniques to investigate chemical and physical properties on a microscopic scale. (mdpi.com)
  • Heavy-ion synchrotrons are used primarily in nuclear physics research. (britannica.com)
  • This dual-degree program welcomes new graduate students to participate in synchrotron-based experimental research. (lsu.edu)
  • From here they are used to generate the synchrotron light used for research. (zdnet.com)
  • The Canadian Light Source, located on the University of Saskatchewan campus in Saskatoon, is Canada's national centre for synchrotron research. (mcgill.ca)
  • Over the past 20 years, synchrotron-based research applications have provided important insight into the geochemical cycling of ions and the chemical and crystallographic properties of minerals in soils and sediments. (elsevier.com)
  • This book provides the most up-to-date information on synchrotron-based research applications in the field of soil, sediment and earth sciences. (elsevier.com)
  • This book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. (routledge.com)
  • Two of Canada s leading innovators in physics have been elected to the leadership of Canadian Light Source Inc. (CLSI), Canada s national synchrotron research facility. (webwire.com)
  • The Canadian Light Source is Canada s national centre for synchrotron research. (webwire.com)
  • The main objective is to highlight the powerful capabilities of Synchrotron radiation (SR) in nanomaterials research aspects. (iucr.org)
  • Synchrotron X‐rays with high brilliance are an indispensable tool for muscle structural research. (els.net)
  • With permission from the Japanese Society for Synchrotron Radiation Research. (els.net)
  • Before traveling here, I did some research and a little bit of reading on cyclotrons and synchrotrons and how they can make tiny things like atoms travel almost the speed of light. (asu.edu)
  • Using synchrotrons for soil research is still a relatively new phenomenon, as researchers develop new ways to improve crop yields and protect ecosystems. (lightsource.ca)
  • A team from the Germans Trias i Pujol Research Institute (IGTP) in Badalona is performing an experiment at the ALBA Synchrotron to obtain for the first time 3D images of cells with this disease. (lightsources.org)
  • Previous research 1 had hinted at an intracellular binding pocket within some chemokine receptors, but the Heptares team were able to verify this unusual site for the first time with the aid of the synchrotron. (diamond.ac.uk)
  • Scientific research and innovation using synchrotron light span hugely diverse areas of activity and has led to advances that bring benefits to Australia and internationally. (ansto.gov.au)
  • Synchrotron radiation is very useful for various fields in both basic and applied research. (or.jp)
  • As an innovation brought by the research, the synchrotron setup used a classic symmetric Michelson interferometer for Fourier processing the data as an alternative to the standard asymmetric scheme typically used in s-SNOM. (lightsources.org)
  • Researchers are now analysing donors' cells in the ALBA Synchrotron to see the changes caused by the disease. (lightsources.org)
  • In addition to the storage ring, a synchrotron light source usually contains a linear accelerator (linac) and another synchrotron which is sometimes called booster in this context. (wikipedia.org)
  • From there they're transferred into another synchrotron, a booster synchrotron where they're accelerated up to the final energy of 3000 million volts before they're injected into the storage ring. (thenakedscientists.com)
  • The objective of this study was to determine if biomedical synchrotron techniques would be effective for imaging ovarian microanatomy, including ovarian follicles, corpora lutea, and the oocyte. (omicsonline.org)
  • Specialized electron synchrotrons, such as the Advanced Photon Source at Argonne National Laboratory , Argonne, Illinois, have been constructed to optimize the production of X-ray synchrotron radiation for structural studies of biological macromolecules and other complex materials. (britannica.com)
  • We hypothesize that synchrotron imaging will provide greater resolution and thereby allow the detection of fine structural details of the ovary compared to conventional ultrasonography. (clinicaltrials.gov)
  • Synchrotron light has revolutionized our view into the sub-microscopic world and has contributed to major innovations in fields including solid-state physics, materials science, environmental sciences, structural biology and chemistry. (innovations-report.com)
  • By organising the leading European Synchrothron facilities in a pan-European Consortium composed of 19 partners, BioStruct-X pioneered integrated European infrastructure provision allowing diverse structural biology synchrotron activities to be organised by structural biologists for the scientific community. (europa.eu)
  • Also called the Diamond Light Source, the Diamond synchrotron began operating in January 2007. (howstuffworks.com)
  • The Proton Synchrotron Booster (PSB), a synchrotron, is the first and smallest circular proton accelerator in the accelerator chain at the CERN Large Hadron Collider injection complex. (wikipedia.org)
  • It contains four superimposed rings with a radius of 25 meters, which take protons with an energy of 6988801088243500000♠50 MeV from the linear accelerator LINAC 2 and accelerate them up to 6990224304708179999♠1.4 GeV, ready to be injected into the Proton Synchrotron. (wikipedia.org)
  • Before the PSB was built in 1972, LINAC 2 injected directly into the Proton Synchrotron, but the greater injection energy provided by the booster allows more protons to be injected and a higher luminosity at the end of the accelerator chain. (wikipedia.org)
  • Thus, the electron synchrotron accelerates electrons, and the proton synchrotron accelerates protons. (britannica.com)
  • The Proton Synchrotron Booster (PSB) is the first circular accelerator in the injector chain to the Large Hadron Collider (LHC) and accelerates protons from 50 MeV to 1.4 GeV. (cern.ch)
  • Using barium sulfate as a contrast material, we obtained microangiographic images of physiologic and pathologic changes consequent to cerebral infarction in mouse brain by monochromatic synchrotron radiation (SR). To achieve high-resolution and high-contrast images, we used a new x-ray camera with a pixel size of 4.5 μm, and we set the energy level at 37.5 keV, just above the K absorption of barium. (ajnr.org)
  • Recently, ex vivo and in vivo microangiography using monochromatic synchrotron radiation (SR) has been suggested as a tool capable of visualizing pathophysiologic changes in small arteries. (ajnr.org)
  • Entire cells or cell nuclei were targeted with 5.35 keV monochromatic X-ray microbeams using a synchrotron radiation (SR) X-ray microbeam irradiation apparatus. (nii.ac.jp)
  • Synchrotron light is created by bending the path of electrons traveling the speed of light around a storage ring. (stanford.edu)
  • Synchrotron light is created when electrons traveling the speed of light take a curved path around a storage ring-emitting electromagnetic light in x-ray through infrared wavelengths. (innovations-report.com)
  • Synchrotron light is exceptionally intense X-ray light, whose properties can be adjusted in a variety of ways. (psi.ch)
  • Synchrotrons use electrons to produce intense beams of light more than a million times brighter than the sun. (ansto.gov.au)
  • A synchrotron light source is a combination of different electron accelerator types, including a storage ring in which the desired electromagnetic radiation is generated. (wikipedia.org)
  • It comprises a complex of electron accelerators that produce synchrotron light - electromagnetic radiation covering a continuum of wavelengths, ranging from infrared to hard X rays (including visible light). (kde.org)
  • Synchrotron radiation and electromagnetic waves2. (indigo.ca)
  • Synchrotron radiations are electromagnetic waves that are emitted in the tangential direction of the orbit when electrons or positrons circulating near the speed of light in an accelerating ring (synchrotron). (els.net)
  • Within the scope of ANNA, the European cooperation project, the Physikalisch-Technische Bundesanstalt (PTB) is working in its laboratory at the electron storage ring BESSY II in Berlin for the first time, together with external users, at selected measuring sites for the use of synchrotron radiation. (innovations-report.com)
  • Synchrotron radiation from electron storage rings10. (indigo.ca)
  • Spectrometer calibrations have been performed at the National Institute of Standards and Technology (formerly the National Bureau of Standards) for over 10 yr using the calculable synchrotron radiation from the SURF II electron storage ring. (spiedigitallibrary.org)
  • See first link about a synchrotron projection TV, because we need something like that light-source here, and see the second link about carbon bicarbonate, because it provides the background chemistry that this Idea is about (and sulfur is mentioned in an annotation, too! (halfbakery.com)
  • This catalyst is the synchrotron light source, which can very efficiently generate quite bright light of just about any pure frequency we want. (halfbakery.com)
  • At PSI, synchrotron light is generated in the Swiss Light Source SLS. (psi.ch)
  • Managed by the Consortium for the Construction, Equipping and Exploitation of the Synchrotron Light Source (CELLS), it is jointly funded by the Spanish and the Catalonian Administration. (kde.org)
  • I'm standing on the catwalk above the Berkeley Lab's Synchrotron, also called the Advanced Light Source, or ALS. (asu.edu)
  • They approached me because they thought I could be the sort of person that could suggest ways to use the synchrotron to help them solve their problem," said Coulthard, a scientist with Canadian Light Source. (thestarphoenix.com)
  • The light shines brilliantly these days at the Stanford Synchrotron Radiation Laboratory (SSRL). (innovations-report.com)
  • Ovaries will be imaged using conventional ultrasonography, synchrotron and histology. (clinicaltrials.gov)
  • Synchrotron hard X-rays represent a class of promising probes for solution-phase reactions due to their strong penetration in ambient environment and solutions. (wiley.com)
  • The femoral BMD was analyzed by dual-energy X-ray absorptiometry (DXA) and the element relative content was determined by synchrotron radiation X-ray fluorescence (SRXRF) microprobe. (hindawi.com)
  • The light is produced when high-energy electrons are forced to travel in a circular orbit inside the synchrotron tunnels by the 'synchronised' application of strong magnetic fields. (ansto.gov.au)
  • Mitchell L. Furst, Rossie M. Graves, Robert P. Madden, "Synchrotron ultraviolet radiation facility (SURF II) radiometric instrumentation calibration facility," Opt. (spiedigitallibrary.org)
  • Up next, our guest scientist will give us the inside story about how the synchrotron works and what seems to be a love of aluminum foil. (asu.edu)
  • University of Saskatchewan and Canadian Synchrotron researchers shed light on esophage. (bio-medicine.org)
  • Prompted by methodological advances in measurements with X-ray free electron lasers, it was realized in the last two years that traditional (or conventional) methods for data collection from crystals of macromolecular specimens can be complemented by synchrotron measurements on microcrystals that would individually not suffice for a complete data set. (springer.com)
  • As one of the pioneering synchrotron facilities in the world, SSRL has served the scientific community for over 35 years by providing outstanding user support and important contributions to science and instrumentation. (stanford.edu)
  • He has been involved in the design and construction of experimental facilities at synchrotrons in the United States, and has served on the CLSI Board of Directors since 2004. (webwire.com)
  • Over the past decade, numerous synchrotron facilities have been established throughout the world. (valorebooks.com)
  • Combined with recent developments in phase contrast methods ( 17 , 20 , 21 ), synchrotron facilities are a powerful tool for noninvasive, volumetric investigation of a broad range of material. (pnas.org)
  • It is assumed that the European X-ray Free Laser will be the most powerful of the existing facilities of synchrotron radiation. (phys.org)
  • In doing so, BioStruct-X created a single gateway to Europe's leading synchrotron facilities and associated infrastructures, ultimately to the benefit of the overall user community. (europa.eu)
  • Moreover, and especially inside synchrotron facilities, the combination of optimal focusing optics and IR area detectors has allowed important breakthroughs in micrometer-scale chemical analysis (µ-FTIR) in several areas of chemistry, biology, medicine, forensics, geology and physics. (lightsources.org)
  • It is one of only eight synchrotrons in the US and the only state-funded facility. (lsu.edu)
  • The start up of SSRL's new synchrotron light facility, SPEAR3, guarantees a world-class program in x-ray science for years to come," said U.S. Secretary of Energy Spencer Abraham. (innovations-report.com)
  • The Victorian Government committed to funding the synchrotron technology and a building to house the facility. (ansto.gov.au)