AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
Survival RateCell SurvivalDisease-Free SurvivalSurvival AnalysisTreatment OutcomeSurvivalGraft SurvivalRetrospective StudiesPrognosisKaplan-Meier EstimateNeoplasm StagingFollow-Up StudiesTime FactorsCombined Modality TherapyProportional Hazards ModelsAntineoplastic Combined Chemotherapy ProtocolsNeoplasm Recurrence, LocalLung NeoplasmsLiver NeoplasmsMultivariate AnalysisAdenocarcinomaLymphatic MetastasisActuarial AnalysisRisk FactorsChemotherapy, AdjuvantProspective StudiesTumor Markers, BiologicalAntineoplastic AgentsLiver TransplantationApoptosisCisplatinCarcinoma, HepatocellularCarcinoma, Squamous CellNeoplasm MetastasisBreast NeoplasmsAge FactorsImmunohistochemistryCohort StudiesPostoperative ComplicationsRecurrenceHepatectomyRegistriesRadiotherapy, AdjuvantStomach NeoplasmsDisease ProgressionCarcinoma, Non-Small-Cell LungDoxorubicinVincristineCyclophosphamideReoperationFluorouracilNeoplasm InvasivenessKidney TransplantationCell Line, TumorBrain NeoplasmsPancreatic NeoplasmsRadiotherapy DosageRisk AssessmentDrug Administration ScheduleLife TablesEsophageal NeoplasmsRemission InductionGraft RejectionCarcinomaColorectal NeoplasmsLymph Node ExcisionPredictive Value of TestsSignal TransductionTransplantation, HomologousMice, Inbred C57BLGastrectomyNeoadjuvant TherapyNeoplasmsPrednisoneIncidenceDisease Models, AnimalEtoposideBile Duct NeoplasmsChemoembolization, TherapeuticTissue DonorsCell ProliferationBone NeoplasmsCardiopulmonary ResuscitationSEER ProgramRectal NeoplasmsHeart ArrestJapanSalvage TherapySarcomaGene Expression Regulation, NeoplasticRadiotherapyImmunosuppressive AgentsChi-Square DistributionCholangiocarcinomaDose FractionationCryopreservationMelanomaMice, Inbred BALB CDeoxycytidineCells, CulturedCause of DeathOvarian NeoplasmsChemoradiotherapyPatient SelectionHead and Neck NeoplasmsDose-Response Relationship, DrugProbabilityAntimetabolites, AntineoplasticTissue SurvivalVinblastineKidney NeoplasmsTreatment FailureProsthesis FailureInfant, NewbornLiving DonorsMutationCarboplatinAnalysis of VariancePneumonectomyOsteosarcomaEsophagectomyReverse Transcriptase Polymerase Chain ReactionPalliative CarePaclitaxelMethotrexateKidney Failure, ChronicBile Ducts, IntrahepaticRadiotherapy, High-EnergyGlioblastomaNasopharyngeal NeoplasmsNeoplasm GradingUnited StatesLymphoma, Non-HodgkinMice, KnockoutBrachytherapySurvivorsSex FactorsBleomycinMicrobial ViabilityLiver FailurePancreas TransplantationProstatic NeoplasmsCarcinoma, Small CellPreoperative CareSeverity of Illness IndexAntibodies, MonoclonalTumor BurdenCryoprotective AgentsHeart TransplantationRNA, MessengerTransplantation, AutologousSkin NeoplasmsBlotting, WesternColonic NeoplasmsProsthesis DesignLymph NodesClinical Trials as TopicCarcinoma, Renal CellDacarbazineRegression AnalysisCytarabineMouth NeoplasmsCadaverGliomaLongevityGene Expression ProfilingDrug Resistance, NeoplasmSurvival of Motor Neuron 1 ProteinSoft Tissue NeoplasmsIfosfamideHodgkin DiseaseProto-Oncogene ProteinsHematopoietic Stem Cell TransplantationInfusions, IntravenousAcute DiseaseMultiple MyelomaPancreatectomyTumor Suppressor Protein p53Precursor Cell Lymphoblastic Leukemia-LymphomaTomography, X-Ray ComputedMice, TransgenicLeucovorinPostoperative CareRenal DialysisTaxoidsNeoplasm ProteinsCell DeathPregnancyOut-of-Hospital Cardiac Arrestalpha-FetoproteinsBone Marrow TransplantationLymphoma, Large B-Cell, DiffuseDose-Response Relationship, RadiationEthylene GlycolVitrificationRandomized Controlled Trials as TopicLeukemia, Myeloid, AcuteAntineoplastic Agents, AlkylatingStatistics, NonparametricFranceSepsis
Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Survival: Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Proportional Hazards Models: Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Neoplasm Recurrence, Local: The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.Lung Neoplasms: Tumors or cancer of the LUNG.Liver Neoplasms: Tumors or cancer of the LIVER.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Lymphatic Metastasis: Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.Actuarial Analysis: The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Cisplatin: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Breast Neoplasms: Tumors or cancer of the human BREAST.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Recurrence: The return of a sign, symptom, or disease after a remission.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Radiotherapy, Adjuvant: Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Stomach Neoplasms: Tumors or cancer of the STOMACH.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Carcinoma, Non-Small-Cell Lung: A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.Doxorubicin: Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.Vincristine: An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)Cyclophosphamide: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.Neoplasm Invasiveness: Ability of neoplasms to infiltrate and actively destroy surrounding tissue.Kidney Transplantation: The transference of a kidney from one human or animal to another.Cell Line, Tumor: A cell line derived from cultured tumor cells.Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Radiotherapy Dosage: The total amount of radiation absorbed by tissues as a result of radiotherapy.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.Remission Induction: Therapeutic act or process that initiates a response to a complete or partial remission level.Graft Rejection: An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.Lymph Node Excision: Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Transplantation, Homologous: Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.Mice, Inbred C57BLGastrectomy: Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)Neoadjuvant Therapy: Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Chemoembolization, Therapeutic: Administration of antineoplastic agents together with an embolizing vehicle. This allows slow release of the agent as well as obstruction of the blood supply to the neoplasm.Tissue Donors: Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Cardiopulmonary Resuscitation: The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.SEER Program: A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)Rectal Neoplasms: Tumors or cancer of the RECTUM.Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.JapanSalvage Therapy: A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Radiotherapy: The use of IONIZING RADIATION to treat malignant NEOPLASMS and some benign conditions.Immunosuppressive Agents: Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.Dose Fractionation: Administration of the total dose of radiation (RADIATION DOSAGE) in parts, at timed intervals.Cryopreservation: Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)Mice, Inbred BALB CDeoxycytidineCells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Chemoradiotherapy: Treatment that combines chemotherapy with radiotherapy.Patient Selection: Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Probability: The study of chance processes or the relative frequency characterizing a chance process.Antimetabolites, Antineoplastic: Antimetabolites that are useful in cancer chemotherapy.Tissue Survival: The span of viability of a tissue or an organ.Vinblastine: Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)Kidney Neoplasms: Tumors or cancers of the KIDNEY.Treatment Failure: A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Infant, Newborn: An infant during the first month after birth.Living Donors: Non-cadaveric providers of organs for transplant to related or non-related recipients.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Carboplatin: An organoplatinum compound that possesses antineoplastic activity.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Pneumonectomy: The excision of lung tissue including partial or total lung lobectomy.Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)Esophagectomy: Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Palliative Care: Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)Paclitaxel: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.Methotrexate: An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Radiotherapy, High-Energy: Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle.Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.Nasopharyngeal Neoplasms: Tumors or cancer of the NASOPHARYNX.Neoplasm Grading: Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm.United StatesLymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Brachytherapy: A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.Survivors: Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Bleomycin: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.Microbial Viability: Ability of a microbe to survive under given conditions. This can also be related to a colony's ability to replicate.Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)Pancreas Transplantation: The transference of a pancreas from one human or animal to another.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Tumor Burden: The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.Cryoprotective Agents: Substances that provide protection against the harmful effects of freezing temperatures.Heart Transplantation: The transference of a heart from one human or animal to another.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Transplantation, Autologous: Transplantation of an individual's own tissue from one site to another site.Skin Neoplasms: Tumors or cancer of the SKIN.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Colonic Neoplasms: Tumors or cancer of the COLON.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Lymph Nodes: They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.Dacarbazine: An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)Mouth Neoplasms: Tumors or cancer of the MOUTH.Cadaver: A dead body, usually a human body.Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)Longevity: The normal length of time of an organism's life.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Drug Resistance, Neoplasm: Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.Survival of Motor Neuron 1 Protein: A SMN complex protein that is essential for the function of the SMN protein complex. In humans the protein is encoded by a single gene found near the inversion telomere of a large inverted region of CHROMOSOME 5. Mutations in the gene coding for survival of motor neuron 1 protein may result in SPINAL MUSCULAR ATROPHIES OF CHILDHOOD.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Ifosfamide: Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Hematopoietic Stem Cell Transplantation: Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.Infusions, Intravenous: The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.Acute Disease: Disease having a short and relatively severe course.Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Leucovorin: The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Taxoids: A group of diterpenoid CYCLODECANES named for the taxanes that were discovered in the TAXUS tree. The action on MICROTUBULES has made some of them useful as ANTINEOPLASTIC AGENTS.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Cell Death: The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.alpha-Fetoproteins: The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.Bone Marrow Transplantation: The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.Lymphoma, Large B-Cell, Diffuse: Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.Dose-Response Relationship, Radiation: The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.Vitrification: The transformation of a liquid to a glassy solid i.e., without the formation of crystals during the cooling process.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.Antineoplastic Agents, Alkylating: A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)France: A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

The role of alternative splicing of the adhesion molecule, CD44, in lymphoid malignancy. (1/23200)

AIM: To investigate the expression of CD44 isoforms containing variant exon 6 (v6) in a well characterised cohort of patients with non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukaemia (CLL), and to correlate this with phenotype and disease course. METHODS: Cryostat sections of OCT embedded diagnostic nodal material from NHL patients and cryopreserved mononuclear preparations from CLL patients were used as sources of RNA. After reverse transcription, PCR was carried out with amplimers positioned at either side of the variant exon insertion site to amplify all possible CD44 isoforms. Those isoforms containing v6 were identified after Southern blotting and hybridisation with a radiolabelled oligonucleotide. RESULTS: Of 32 NHL samples analysed, 16 did not express CD44 isoforms containing v6, six expressed an isoform containing exon v6 alone, and 10 expressed v6 long isoforms which contained exon v6 in addition to other variant exons. These data did not correlate with lymphoma classification, disease staging, or the presence or absence of extranodal disease. However, those patients expressing v6 long CD44 isoforms had a worse overall survival than those that did not. The plateau of the survival curves was 50% compared with 82%. No v6 long isoforms were detected in the 21 CLL samples investigated. CONCLUSIONS: The expression of v6 long CD44 isoforms is associated with aggressive disease in NHL, independent of grade, stage, or presence of extranodal disease.  (+info)

Expression of extracellular matrix proteins in cervical squamous cell carcinoma--a clinicopathological study. (2/23200)

AIM: To evaluate the intracellular and peritumoral expression of matrix proteins in squamous cell carcinoma of the uterine cervix using immunohistochemistry. METHODS: 71 squamous cell carcinomas and 10 controls were stained for laminin, fibronectin, and collagen IV. Cytoplasmic staining in tumour cells and peritumoral deposition of matrix proteins were evaluated. The association between staining results and patient age, tumour stage, histological grade, and survival was studied. RESULTS: Positive cytoplasmic staining for laminin, fibronectin, and collagen IV was observed in 17 (23.9%), 27 (38%), and 10 (14.1%) cases, respectively. Staining for laminin was most pronounced in the invasive front of tumour islands, while for fibronectin and collagen IV it appeared to be diffuse. Peritumoral staining for laminin and collagen IV was detected in 12 cases (16.9%). Early stage (Ia1-Ia2) tumours were uniformly negative for all three proteins. Cytoplasmic staining for laminin correlated with positive staining for fibronectin and collagen IV, and with the presence of a peritumoral deposition of collagen IV and laminin. There was no correlation with any of the three markers between staining results and patient age, stage, grade, or survival. CONCLUSIONS: Expression of extracellular matrix proteins in some cervical squamous cell carcinomas might reflect the enhanced ability of these tumours to modify the peritumoral stroma. This ability seems to be absent in early stage tumours. The correlation between intracytoplasmic and peritumoral expression of matrix proteins supports the evidence of their synthesis by tumour cells. However, this property did not correlate with disease outcome in this study.  (+info)

Is hospital care involved in inequalities in coronary heart disease mortality? Results from the French WHO-MONICA Project in men aged 30-64. (3/23200)

OBJECTIVES: The goal of the study was to assess whether possible disparities in coronary heart disease (CHD) management between occupational categories (OC) in men might be observed and contribute to the increasing inequalities in CHD morbidity and mortality reported in France. METHODS: The data from the three registers of the French MONICA Collaborative Centres (MCC-Lille, MCC-Strasbourg, and MCC-Toulouse) were analysed during two period: 1985-87 and 1989-91. Acute myocardial infarctions and coronary deaths concerning men, aged 30-64 years, were included. Non-professionally active and retired men were excluded. Results were adjusted for age and MCC, using a logistic regression analysis. RESULTS: 605 and 695 events were analysed for 1985-87 and 1989-91, respectively. Out of hospital cardiac arrests, with or without cardiac resuscitation, and 28 day case fatality rates were lower among upper executives in both periods. A coronarography before the acute event had been performed more frequently in men of this category and the proportion of events that could be hospitalised was higher among them. In both periods, the management of acute myocardial infarctions in hospital and prescriptions on discharge were similar among occupational categories. CONCLUSIONS: For patients who could be admitted to hospital, the management was found to be similar among OCs, as was the 28 day case fatality rate among the hospitalised patients. In contrast, lower prognosis and higher probability of being hospitalised after the event among some categories suggest that pre-hospital care and the patient's conditions before the event are the primary factors involved.  (+info)

Intrahepatic recurrence after curative resection of hepatocellular carcinoma: long-term results of treatment and prognostic factors. (4/23200)

OBJECTIVE: This study aimed to evaluate the long-term results of treatment and prognostic factors in patients with intrahepatic recurrence after curative resection of hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA: Recent studies have demonstrated the usefulness of re-resection, transarterial oily chemoembolization (TOCE), or percutaneous ethanol injection therapy (PEIT) in selected patients with intrahepatic recurrent HCC. The overall results of a treatment strategy combining these modalities have not been fully evaluated, and the prognostic factors determining survival in these patients remain to be clarified. METHODS: Two hundred and forty-four patients who underwent curative resection for HCC were followed for intrahepatic recurrence, which was treated aggressively with a strategy including different modalities. Survival results after recurrence and from initial hepatectomy were analyzed, and prognostic factors were determined by univariate and multivariate analysis using 27 clinicopathologic variables. RESULTS: One hundred and five patients (43%) with intrahepatic recurrence were treated with re-resection (11), TOCE (71), PEIT (6), systemic chemotherapy (8) or conservatively (9). The overall 1-year, 3-year, and 5-year survival rates from the time of recurrence were 65.5%, 34.9%, and 19.7%, respectively, and from the time of initial hepatectomy were 78.4%, 47.2%, and 30.9%, respectively. The re-resection group had the best survival, followed by the TOCE group. Multivariate analysis revealed Child's B or C grading, serum albumin < or = 40 g/l, multiple recurrent tumors, recurrence < or = 1 year after hepatectomy, and concurrent extrahepatic recurrence to be independent adverse prognostic factors. CONCLUSIONS: Aggressive treatment with a multimodality strategy could result in prolonged survival in patients with intrahepatic recurrence after curative resection for HCC. Prognosis was determined by the liver function status, interval to recurrence, number of recurrent tumors, any concurrent extrahepatic recurrence, and type of treatment.  (+info)

Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study 4. (5/23200)

OBJECTIVE: To assess the prognostic factors for local recurrence in Wilms tumor. SUMMARY BACKGROUND DATA: Current therapy for Wilms tumor has evolved through four studies of the National Wilms Tumor Study Group. As adverse prognostic factors were identified, treatment of children with Wilms tumor has been tailored based on these factors. Two-year relapse-free survival of children in the fourth study (NWTS-4) exceeded 91%. Factors once of prognostic import for local recurrence may lose their significance as more effective therapeutic regimens are devised. METHODS: Children evaluated were drawn from the records of NWTS-4. A total of 2482 randomized or followed patients were identified. Local recurrence, defined as recurrence in the original tumor bed, retroperitoneum, or within the abdominal cavity or pelvis, occurred in 100 children. Using a nested case-control study design, 182 matched controls were selected. Factors were analyzed for their association with local failure. Relative risks and 95% confidence intervals were calculated, taking into account the matching. RESULTS: The largest relative risks for local recurrence were observed in patients with stage III disease, those with unfavorable histology (especially diffuse anaplasia), and those reported to have tumor spillage during surgery. Multiple regression analysis adjusting for the combined effects of histology, lymph node involvement, and age revealed that tumor spillage remained significant. The relative risk of local recurrence from spill was largest in children with stage II disease. The absence of lymph node biopsy was also associated with an increased relative risk of recurrence, which was largest in children with stage I disease. The survival of children after local recurrence is poor, with an average survival rate at 2 years after relapse of 43%. Survival was dependent on initial stage: those who received more therapy before relapse had a worse prognosis. CONCLUSIONS: This study has demonstrated that surgical rupture of the tumor must be prevented by the surgeon, because spills produce an increased risk of local relapse. Both local and diffuse spills produce this risk. Stage II children with local spill appear to require more aggressive therapy than that used in NWTS-4. The continued critical importance of lymph node sampling in conjunction with nephrectomy for Wilms tumor is also established. Absence of lymph node biopsy may result in understaging and inadequate treatment of the child and may produce an increased risk of local recurrence.  (+info)

Serum triglyceride: a possible risk factor for ruptured abdominal aortic aneurysm. (6/23200)

BACKGROUND: We aimed to determine the relationship between ruptured abdominal aortic aneurysm (AAA) and serum concentrations of lipids and apolipoproteins. METHODS: A cohort of 21 520 men, aged 35-64 years, was recruited from men attending the British United Provident Association (BUPA) clinic in London for a routine medical examination in 1975-1982. Smoking habits, weight, height and blood pressure were recorded at entry. Lipids and apolipoproteins were measured in stored serum samples from the 30 men who subsequently died of ruptured AAA and 150 matched controls. RESULTS: Triglyceride was strongly related to risk of ruptured AAA. In univariate analyses the risk in men on the 90th centile of the distribution relative to the risk in men on the 10th (RO10-90) was 12 (95% confidence interval [CI] : 3.8-37) for triglyceride, 5.5 (95% CI: 1.8-17) for apolipoprotein B (apoB) (the protein component of low density lipoprotein [LDL]), 0.15 (95% CI : 0.04-0.56) for apo A1 (the protein component of high density lipoprotein [HDL]), 3.7 (95% CI: 1.4-9.4) for body mass index and 3.0 (95% CI: 1.1-8.5) for systolic blood pressure. Lipoprotein (a) (Lp(a)) was not a significant risk factor (RO10-90 = 1.6, 95% CI: 0.6-3.0). In multivariate analysis triglyceride retained its strong association. CONCLUSION: Triglyceride appears to be a strong risk factor for ruptured AAA, although further studies are required to clarify this. If this and other associations are cause and effect, then changing the distribution of risk factors in the population (by many people stopping smoking and adopting a lower saturated fat diet and by lowering blood pressure) could achieve an important reduction in mortality from ruptured AAA.  (+info)

Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men. (7/23200)

BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors.  (+info)

Socioeconomic inequalities and disability pension in middle-aged men. (8/23200)

BACKGROUND: The issue of inequalities in health has generated much discussion and socioeconomic status is considered an important variable in studies of health. It is frequently used in epidemiological studies, either as a possible risk factor or a confounder and the aim of this study was to analyse the relation between socioeconomic status and risk of disability pension. METHODS: Five complete birth year cohorts of middle-aged male residents in Malmo were invited to a health survey and 5782 with complete data constituted the cohort in this prospective study. Each subject was followed for approximately 11 years and nationwide Swedish data registers were used for surveillance. RESULTS: Among the 715 men (12%), granted disability pension during follow-up, three groups were distinguished. The cumulative incidence of disability pension among blue collar workers was 17% and among lower and higher level white collar workers, 11% and 6% respectively. With simultaneous adjustment for biological risk factors and job conditions, the relative risk for being granted a disability pension (using higher level white collar workers as reference) was 2.5 among blue collar workers and 1.6 among lower level white collar workers. CONCLUSIONS: Socioeconomic status, as defined by occupation, is a risk factor for being granted disability pension even after adjusting for work conditions and other risk factors for disease.  (+info)

Liver Cancer Survival RatesLiver Cancer Survival Rates
a) localized resectable- the tumor is located in one place (T1-T2),. b) localized unresectable - the tumor is present in one place however cannot be removed,. c) advanced - the tumor has spread to other organs,. d) recurrent - the cancer is back after treatment.. Unfortunately, liver cancer survival rates are low as the tumor can be undetected for a long time till any signs appear. More than a half of people affected are men; the common age of liver cancer is 60.. The liver cancer survival rates worldwide show that 7% of patients live up to 5 year after diagnosis. If the cancer is removed surgically, 75% of liver cancer patients can live one more year, 30% reach the survival mark of 5 years and 50% - 3 years.. In terms of primary cancer the liver cancer survival rates are quite high provided that a liver transplant can be performed. Liver cancer survival rates reach 5 years in 75% of cases. For metastatic cases liver transplants have a survival rate coming to zero because in some time cancer ...
stomach cancer survival rates « Symptoms Of Cancerstomach cancer survival rates « Symptoms Of Cancer
As a patient, you need to realize that a medical doctor may well never be able to predict your life expectancy just after your diagnosis is confirmed. As a result Stomach Cancer Survival Rates - Know Your Survival Odds , asking for your survival rate could possibly be a little awkward and appropriate. On the other hand stages of ovarian cancer, they may give you their honest opinion. When you ask for the percentage of survival with this type of cancer, your physician will give you an answer depending on statistical reports. And often last stages of cancer, they favor giving the answer according to the stage of cancer you happen to be at present into.. Basically, there are four stages of stomach cancer. But since stages 1-2 have two phases under every stage and stage 3 has three phases, it actually looks like the whole cancer development has 8 phases in total stages of colon cancer, with every phase having unique Stomach Cancer Survival Rate.. Cancer, in general, has the highest rate of survival ...
Thyroid Cancer Survival Rate - Survival Rates Based on Stages and TypesThyroid Cancer Survival Rate - Survival Rates Based on Stages and Types
Thyroid cancer survival rate is high when compared to other cancers. It is a cancer but not as deadly as breast cancer, leukemia or HIV. The average survival rate of this cancer is actually 95%. It means there is a high chance for a patient to get cured. However, you must not be confident regarding
5 year survival rates lung cancer uk by stage | Zanran5 year survival rates lung cancer uk by stage | Zanran
Data & statistics on 5 year survival rates lung cancer uk by stage: 5-year age adjusted relative survival rate for patients diagnosed with lung cancer in selected European countries 1991-1999. Survival measured up to 2003 according to EUROCARE 4., 5-year age adjusted relative survival rate for patients diagnosed with lung cancer 1991-1999. Survival measured up to 2003 according to EUROCARE 4., Outcome of lung cancer treatment...
NJ trails nation in cancer survival rate - CancerNJ trails nation in cancer survival rate - Cancer
The department did note a significant racial disparity, however, with survival rates for white men and women about 10 percentage points higher than those for black men and women. That was similar to the national racial gap.. Bresnitz said the racial differences may be because blacks are being diagnosed later since early detection generally means a better outcome. In addition, blacks may not have the same access to treatment and support services, he said.. The department also noted that survival rates vary greatly by type of cancer, sex and age.. The report found that the overall survival rate was boosted because people with the most common cancers - breast, cervical, colorectal, lung and prostate - were living longer than they did 20 years ago.. The state outpaces the nation in the survival rate for ovarian cancer, but lags when it comes to endometrial cancer and cancers of the cervix, skin, mouth and brain.. source - AP ...
Cancer survival rates are upCancer survival rates are up
Cancer survival rates are at the highest ever with more than 2,000 more people recovering from the disease this year able to enjoy Christmas with their families.
Cancer survival rates to skyrocket: study | Sky News AustraliaCancer survival rates to skyrocket: study | Sky News Australia
The number of people beating cancer or living with the disease is expected to increase by 73 per cent in the next 22 years, according to a new study by Queensland researchers. The mortality study by Cancer Council Queensland was released on Wednesday and looked at the survival patterns among two million Australian cancer patients across 13 types of cancer. The report introduces a more accurate measure to calculate 10-year cancer survival rates, with improvements to mortality rates being attributed to advances in diagnosis methods, treatment, and support. Image: Getty
Liver cancer survival rate - Herbal Active Liver Detox - Nov 22, 2017Liver cancer survival rate - Herbal Active Liver Detox - Nov 22, 2017
Liver cancer survival rate - Survival rate for liver cancer without treatment? - Yahoo Answers. We provides LiverActive Liver Detox formula contains several natural ingredients to help maintain a healthy liver. Listen to your liver and dont ignore the warning signs.
What are breast cancer survival rates in the U.S.? | GreenAnswersWhat are breast cancer survival rates in the U.S.? | GreenAnswers
It depends upon the stage of breast cancer. For stage 0-1 has a 100% survival rate. Stage two has a 81-82% survival rate. Stage three has a 54-67% survival rate. Finally stage four has a 20% survival rate.. ...
CBD From Marijuana Plus Chemotherapy Tripled Cancer Survival Rates - CannarketCBD From Marijuana Plus Chemotherapy Tripled Cancer Survival Rates - Cannarket
Studies show CBD From Marijuana Plus Chemotherapy Tripled Cancer Survival Rates In Mice Mice with pancreatic cancer treated with a combination of ca
Liver Cancer Survival Rates - Vitamin AgentLiver Cancer Survival Rates - Vitamin Agent
Liver cancer survival rates indicate the chances a cancer patient has of surviving the disease for a specified length of time. The rates are by no means a definite indicator of what will happen to a patient; they can at best predict a patients chances of what might happen to him, if a type of treatment plan is opted for, based on what has happened to other patients in similar circumstances. They serve as a guide to a patient and his family to know what they can expect if they choose a particular type of treatment or if they should consider one at all rather than just opt for pain relievers and sedation.. The liver is the largest gland in the body that performs the many vital functions of storing vitamins and nutrients, producing proteins that are required for blood clotting, creating bile required for digestion and of breaking down and filtering toxins from blood.. There are two types of liver cancer; primary liver cancer which begins in the liver tissue itself and metastasized liver cancer ...
Clinical trial looks to improve pancreatic cancer survival ratesClinical trial looks to improve pancreatic cancer survival rates
Researchers at Georgia Regents University Cancer Center are investigating a new avenue of treatment to help boost poor pancreatic cancer survival rates.
A diet low in fats could improve cancer survival rates in children - Child Cancer SupportA diet low in fats could improve cancer survival rates in children - Child Cancer Support
A diet lower in fats could potentially increase the cancer survival rate of overweight children suffering lymphoblastic leukemia, a new study suggests.
Esophageal Cancer Survival Rate - Health HeartyEsophageal Cancer Survival Rate - Health Hearty
The 5-year esophageal cancer survival rate does show how grievous the disease is, but that doesnt mean there is absolutely no chance of a person surviving this condition for more than 5 years.
What Factors Impact The Pancreatic Cancer Survival Rate? - CancerWhat Factors Impact The Pancreatic Cancer Survival Rate? - Cancer
The pancreatic cancer survival rates have been improving with time, but still, there has not been much success in finding its cure. According to the American...
Clinicopathologic characteristics and prognosis of remnant gastric cancerClinicopathologic characteristics and prognosis of remnant gastric cancer
The 5-year overall survival rate of all patients was 58% (Fig. 1). The 5-year overall survival rates in the MD and BD groups were 45% and 79%, respectively; those in the B1 and B2 groups were 55% and 60%, respectively. No significant difference in survival was detected in either pair of groups (P= 0.064 and P= 0.431, respectively) (Figs. 2, 3). In univariate analysis, presence of symptoms and curability were significantly associated with overall survival (P=0.005, hazard ratio [HR]=4.567, 95% confidence interval [CI], 1.579-13.212; P= 0.026, HR= 3.195, 95% CI, 1.149-8.882). In multivariate analysis, age, presence of symptoms and curability was significantly associated with overall survival (P= 0.032, HR= 5.241, 95% CI, 1.158-23.723; P= 0.005, HR = 5.086, 95% CI, 1.642-15.750; P= 0.034, HR= 3.165, 95% CI, 1.088-9.208). In Fig. 4, there were significant differences in overall survival rates according to age, presence of symptoms and curability (P = 0.047, P = 0.019, P = 0.002) (Table 4 ...
Canada Pancreatic Cancer Survival Rate - Gallbladder RepairingCanada Pancreatic Cancer Survival Rate - Gallbladder Repairing
Canada Pancreatic Cancer Survival Rate ake of this requires a large opening in the bile which will allow you to get rid gallbladderb a
Cancer survival rates climb in Spain - The LocalCancer survival rates climb in Spain - The Local
Spain saw a strong rise in five-year cancer survival rates from 1995 to 2009, but poorer countries are missing out on the benefits of improved diagnosis and treatment methods, a major new global study shows.
UK Cancer Survival Rates Lag Behind Rest of EuropeUK Cancer Survival Rates Lag Behind Rest of Europe
Macmillan Cancer Support research has revealed that cancer survival rates in the UK are still lower than in many European countries.
Stage Four Liver Cancer Survival RateStage Four Liver Cancer Survival Rate
Do you want to know the stage four liver cancer survival rate? Will you get hopes or discouragement once you find out? There is a risk involved in knowing
Cancer survival rates in Canada and other countries per ICBP dataCancer survival rates in Canada and other countries per ICBP data
Learn about cancer survival rates in Canada as well as in Canada, Australia, Denmark, Ireland, New Zealand, Norway and the United Kingdom.
Cancer Survival Rates Skew Among Rich And Poor Aussies | triplem networkCancer Survival Rates Skew Among Rich And Poor Aussies | triplem network
Australian cancer survival rates have widened among the nations rich and poor across the last three decades, with researchers now calling for
UK cancer survival rate lowest in Europe - TelegraphUK cancer survival rate lowest in Europe - Telegraph
Cancer survival rates in Britain are among the lowest in Europe, according to the most comprehensive analysis of the issue yet produced.
When Heart Is in Crisis, High Blood Pressure a... ( Study finds better survival rates a y...)When Heart Is in Crisis, High Blood Pressure a... ( Study finds better survival rates a y...)
Health,...Study finds better survival rates a year after intensive care ...TUESDAY March 23 (HealthDay News) -- High blood pressure -- even abov...Their study which involved 119151 people admitted to ICUs for chest ...Survival was poorest for the one-quarter of people who had the lowest ...,When,Heart,Is,in,Crisis,,High,Blood,Pressure,a,Good,Sign,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Five Year Survival Rate For Metastatic Breast Cancer | Survival ShelterFive Year Survival Rate For Metastatic Breast Cancer | Survival Shelter
Targeted therapy, targeted therapies are drugs that interfere with one specific property or function of a cancer cell, rather than acting to kill all rapidly growing cells indiscriminately. The goal is to completely rid the body of leukemia cells that have not been found by common blood or marrow tests. Understanding survival rates, survival rates show how many people live for a certain length of time after being told they have cancer. This means these factors may increase your chances of getting acute lymphoblastic leukemia. Types of supportive and preventive treatments that can be used for patients undergoing treatment for leukemia include the following: Vaccines against the flu or pneumonia Blood or platelet transfusions Anti-nausea medications Antibiotics or antiviral medications to treat or prevent infections White blood cell growth factors. But remember that statistics are based on survival large groups of people. People whose AML doesnt come back (relapse) in 5 bead years are usually ...
Association between Body Mass Index and Cancer Survival in a Pooled Analysis of 22 Clinical Trials | Cancer Epidemiology,...Association between Body Mass Index and Cancer Survival in a Pooled Analysis of 22 Clinical Trials | Cancer Epidemiology,...
In an analysis of 22 clinical trials representing 14 different cancer/treatment combinations, the association between BMI and survival was not consistent across cancer type or stage. There was no statistically significant evidence that BMI at a cutpoint of 25 kg/m2 was associated with overall survival. However, there was good evidence that the relationship between BMI and cancer survival differed by sex. On average, elevated BMI was associated with better overall survival in males, but neither better nor worse overall survival in females. This association was maintained when sex-specific cancers were excluded, when treatment regimens were restricted to dose based on BSA, and when early-stage cancers were excluded. The results remained consistent when a BMI cutpoint of 30 kg/m2 was examined and when analyses were restricted to individuals who survived at least one year following trial enrollment. The latter analysis emphasizes the potentially durable impact of BMI on long-term survival.. The ...
Improved breast cancer survival rates linked to smaller tumors | EurekAlert! Science NewsImproved breast cancer survival rates linked to smaller tumors | EurekAlert! Science News
A new study finds that the size of newly diagnosed breast cancers has shifted towards smaller tumors, even within conventional cancer stage categories, and that this shift accounts for a proportion of the improvement seen in breast cancer survival over the last 30 years.
Pembrolizumab Long-Term Survival Rate Could Reach 25% in NSCLCPembrolizumab Long-Term Survival Rate Could Reach 25% in NSCLC
Treatment with pembrolizumab could elicit long-term survival rates of 21% to 25% for previously-treated patients with PD-L1–positive non–small cell lung cancer compared with 3% to 4% for docetaxel.
5 year survival rates lung cancer uk by stage | Zanran5 year survival rates lung cancer uk by stage | Zanran
Data & statistics on 5 year survival rates lung cancer uk by stage: Survival outcomes vary depending on age at diagnosis and stage of disease, but are relatively poor for lung cancer patients at any stage, with only 11% overall surviving for five years or more., Outcomes have improved only marginally over time, with a fiveyear survival of 12% among those diagnosed between 1997 and 2003 compared with 10% among those diagnosed between 1977 and 1981., Large exposures to ionising radiation at an early age...
Cancer survival rate: can increase the anxiety | merinewsCancer survival rate: can increase the anxiety | merinews
One of the first questions many people ask when first diagnosed with cancer is about their prognosis. They might want to know whether the cancer is relatively easy or more difficult to cure. The doctor cant predict the future, but often they give the estimates based on the experiences of other people with the same cancer. Survival statistics can be confusing and frightening. Survival rates cant tell about the situation specifically. The statistics may be impersonal and not very helpful, said Dr. K.K. Aggarwal, Padma Shri and Dr B C Roy National Awardee and President, Heart Care Foundation of India.
Survival Frog Discount Code - Survival FrogSurvival Frog Discount Code - Survival Frog
survival frog charger, survival frog reviews, survival frog, survival frog batteries, survival frog discount code, survival frog tact bivvy, survival frog tent, survival frog hand warmer, survival frog vs crash safe, survival frog laser
UK breast cancer survival improvement best in EuropeUK breast cancer survival improvement 'best in Europe'
Breast cancer survival rates in the UK have improved at a stronger pace than in the rest of western European, it has been claimed.
Are breast cancer survival rates meaningful? - LifeAre breast cancer survival rates meaningful? - Life
Just because you can measure something, doesnt mean that it is a good proxy from which to draw a conclusion.. In the case of web sites, one proxy used to measure "success" is an increasing number of page views over time. But if you redesign your site to make it easier for visitors to find what they are looking for, page views (per session) may decline. That would be a good thing, although its counter to the belief that more is better.. Turning to cancer, a similar counterintuitive proxy is "survival rate.". ...
Cancer Survival Rate Visualization | YH Michael WangCancer Survival Rate Visualization | YH Michael Wang
This is a project I worked for CPSC 546 - Data and Information Visualization. It presents the 5 to 20-year survival rate for different type of cancer.
Kidney Notes: The above figure compares long term survival in a subgroup of...Kidney Notes: The above figure compares long term survival in a subgroup of...
The above figure compares long term survival in a subgroup of a trial that was published in Circulation in 1980. This was a randomized controlled trial of just over 1000 patients with known cardiovascular disease who were treated with medical therapy alone. The patients were randomized to two treatment groups and were followed for 5 years. In the primary analysis, there was no statistically significant difference in survival between the two groups. However, a subgroup analysis that compared only patients with 3-vessel disease and LV dysfunction at baseline (~200 patients in each group) found that the outcomes were significantly better in group B (p=0.025).. So what was this treatment that was so successful in reducing mortality in group B? There was no treatment. The patients were randomized to the two groups and then simply followed with usual therapy. This study was designed to show the danger of subgroup analyses and why they should be taken with a grain of salt. When the authors looked ...
As cancer survival rate grows, so does number of new casesAs cancer survival rate grows, so does number of new cases
Even as cancer treatment improves and survival rates go up, so too does the number of people afflicted with the deadly disease, experts said ahead of World Cancer Day.
Plus itPlus it
Despite the progressive and incurable nature of almost all MBC, median survival after diagnosis with metastatic disease has been increasing, resulting in a growing number of women living with MBC in the United States. The increased survival is especially noted for women diagnosed at younger ages. We estimate a 2-fold increase in 5-year relative survival rate from 18% to 36%, for women diagnosed with de novo stage IV at age 15-49 between 1992-1994 and 2005-2012, respectively, translating into an increase of approximately one third in the number of women living with MBC, from 105,354 in 1990 to 138,622 in 2013. We further project that by 2017, there will be 154,794 women living with MBC in the United States.. To our knowledge, this is the first time that the number of women living with MBC in the United States has been estimated. These estimates provide a new perspective on the population burden of breast cancer and have great potential significance to the research and advocacy community working ...
Cure-ious About Mixture Models? Accounting for Heterogeneity in Survival..."Cure"-ious About Mixture Models? Accounting for Heterogeneity in Survival...
Survival analysis plays a key role in many cost-effectiveness analyses and published guidelines are available to support the use of standard methods of survival extrapolation. However, the advent of new technologies with different methods of action, particularly in oncology, has changed the nature of survival and, in some cases, introduced the possibility of "cure.". Standard methods of extrapolation may struggle to capture these survival patterns and, hence, fail to capture the full value associated with these new technologies. During this webinar, presenters will recap the importance and relevance of extrapolation for survival analysis, introduce the concept of heterogeneity among patients in terms of survival, and demonstrate the implications for the use of standard approaches to survival extrapolation.. More advanced approaches involving mixture and mixture cure modelling will be presented and explored as possible solutions to capture and account for this heterogeneity. In addition, the ...
Defining and ranking effects of individual agents based on survival times of cancer patients treated with combination...Defining and ranking effects of individual agents based on survival times of cancer patients treated with combination...
An important problem in oncology is comparing chemotherapy (chemo) agents in terms of their effects on survival or progression-free survival time. When the goal is to evaluate individual agents, a difficulty commonly encountered with observational data is that many patients receive a chemo combination including two or more agents. Because agents given in combination may interact, quantifying the contribution of each individual agent to the combinations overall effect is problematic. Still, if on average combinations including a particular agent confer longer survival, then that agent may be considered superior to agents whose combinations confer shorter survival. Motivated by this idea, we propose a definition of individual agent effects based on observational survival data from patients treated with many different chemo combinations. We define an individual agent effect as the average of the effects of the chemo combinations that include the agent. Similarly, we define the effect of each pair ...
Ovarian Cancer: More Deadly Than Breast Cancer - Forbidden NewsOvarian Cancer: More Deadly Than Breast Cancer - Forbidden News
A couple years ago I was questioned if I knew what the most fatal gynecologic most cancers was and I answered "Perfectly, breast most cancers of program." Oh, how I was incorrect. The American Most cancers Culture estimates that the common 5 12 months survival rate of breast most cancers at any phase to actually be 89 p.c. Although no most cancers is great which is a very great rate. The right reply to the query is ovarian most cancers, and its 5 12 months survival rate (believed by the American most cancers modern society) is only 46 p.c. We want to find out why this most cancers is so fatal.. Most cancers is a risky and mysterious matter to people today that never know a great deal about it. Perfectly, anyone is made up of cells, cells are what make up tissue and tissue is what makes up our organs. Generally when a cell will get previous and worn out it dies just like we do and a new cell takes its place. Our human body produces these new cells by escalating and dividing wholesome cells. At ...
March | 2016 | Just Bad for YouMarch | 2016 | Just Bad for You
While this is a more complex issue than I can adequately address in this post, I am going to include a short answer I wrote on Quora about a year after my own diagnosis with lung cancer - at which time I had just about reached my "statistical" expectation for life expectancy with a Stage 4 diagnosis. You see, according to the abstract numbers you get through pretty much any Internet search on survival rates, Stage 4 lung cancer does not fair very well. If you believe the numbers, youre just supposed to die. Quickly. So I did some "soul searching," and came to terms with what dying might mean to me. Then I moved along because, for one thing, I know a little bit about reading statistics and it was clear that they did not apply to me. (My demographic, for one thing, was not properly represented, nor was the collection of treatments that had been introduced in the previous five to ten years, which is about how out of date most survival rate statistics are when you get them.) Besides, even if cancer ...
Cancer study finds adolescents dont get same access to latest treatments as younge... ( The overall survival rate from cance....Cancer study finds adolescents don't get same access to latest treatments as younge... ( The overall survival rate from cance....
Health, ...The overall survival rate from cancer now is lower in older adolescent...Nationally cure rates in children younger than 15 with cancer have im...This can be attributed to the fact that adolescents and young adults d...The study is published in the December issue of the Journal of Pediatr...,Cancer,study,finds,adolescents,dont,get,same,access,to,latest,treatments,as,younger,patients,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Five-year cancer survival rates in the USA - Our World in DataFive-year cancer survival rates in the USA - Our World in Data
Percentage of cancer patients surviving at least five years since diagnosis, by cancer type. This data is available to view by sex and race.
Tick box questionnaire could significantly improve esophageal cancer survival rates UNIVERSITY C - ecancerTick box questionnaire could significantly improve esophageal cancer survival rates UNIVERSITY C - ecancer
A simple health questionnaire could be a highly effective tool to pre-screen people for early signs of oesophageal cancer, enabling much earlier diagnosis an
Can You Die from Skin Cancer? Survival Rates and PreventionCan You Die from Skin Cancer? Survival Rates and Prevention
Skin cancer has a high cure rate, but only if caught early. Depending on the type, skin cancer can grow rapidly and become life-threatening.
Cancer survival rates greatly increased by early detection - Ellon TimesCancer survival rates greatly increased by early detection - Ellon Times
Cancer isn’t what it used to be. More people are surviving than ever before, thanks to research breakthroughs, treatment advances and finding cancer early.
PDK SELAYANG / CBR SELAYANG: Bladder Cancer Survival RatesPDK SELAYANG / CBR SELAYANG: Bladder Cancer Survival Rates
Cancer is a life-changing experience. And although theres no surefire way of preventing a recurrence, you can take steps to feel and stay healthy. Eating plenty of fruits, veggies, whole grains, and keeping to modest portions of lean meat is a great start. If you smoke, stop. Limit alcohol to one or two drinks a day, if you drink. Daily exercise and regular checkups will also support your health and give you peace of mind ...
Survival Rate Is Not the Best Way to Judge Cancer Spending | The Law Office Of Gerald Oginski, LLCSurvival Rate Is Not the Best Way to Judge Cancer Spending | The Law Office Of Gerald Oginski, LLC
Survival rates describe the number of people who live a certain time after a diagnosis. For example, the 5-year survival rate for lung cancer is 16.8%
Medicare spending disparities not reflected in cancer survival rates - amednews.comMedicare spending disparities not reflected in cancer survival rates - amednews.com
Cancer experts say patient-centered treatment alternatives are needed in light of a study finding no direct correlation between regional spending variations and outcomes.
Prostate Cancer Survival Rate Without Treatment - CancerOzProstate Cancer Survival Rate Without Treatment - CancerOz
Prostate cancer survival rate without treatment - Survival rates for prostate cancer - Survival rates tell what level of individuals with a similar sort and phase of cancer are as yet alive a specific timeframe (ordinarily 5 years) after they have been analyzed.
Has Prenatal Screening Influenced the Prevalence of Comorbidities Associated With Down Syndrome and Subsequent Survival Rates?Has Prenatal Screening Influenced the Prevalence of Comorbidities Associated With Down Syndrome and Subsequent Survival Rates?
OBJECTIVES: With this study we aimed to compare survival rates for children with Down syndrome in 2 time periods, 1 before prenatal screening (1988-1990) and 1 contemporaneous with screening (1998-2000), and to examine the frequency of comorbidities and their influence on survival rates. METHODS: Record-linkage was performed between the population-based Victorian Birth Defects Register and records of deaths in children up to 15 years of age collected under the auspice of the Consultative Council on Obstetric and Pediatric Mortality and Morbidity. Cases of Down syndrome were coded according to the presence or absence of comorbidities by using the International Classification of Diseases, Ninth Revision classification of birth defects. Kaplan-Meier survival functions and log rank tests for equality of survival distributions were performed. RESULTS: Of infants liveborn with Down syndrome in 1998-2000, 90% survived to 5 years of age, compared with 86% in the earlier cohort. With fetal deaths ...
Cancer survival rates - WikipediaCancer survival rates - Wikipedia
According to the latest numbers released by the United States Center for Disease Control and Prevention (CDC), cancer is the second leading cause of death in the United States, surpassed only by heart disease. The CDC reports over half a million deaths from cancer in 2014, and the United States National Cancer Institute (NCI) reports 454.8 new cases of cancer per 100,000 people per year, with an estimate of 1,685,210 new cases of cancer diagnosed in 2016. Between 2008 and 2012, the number of cancer deaths was 171.2 per 100,000 men and women per year. Globally, the leading cause of cancer death in high income economies in 2015 was trachea, bronchus, and lung cancers (49.5 deaths per 100,000), followed by colon and rectum cancers (27.5 deaths per 100,000) and breast cancer (15.6 per 100,000). Cancer is not a leading cause of death in low income economies, where the leading cause of death is communicable diseases. Cancer survival rates vary by the type of cancer, stage at diagnosis, treatment given ...
Cancer Survival rates in Europe - BASO ~ The Association For Cancer SurgeryCancer Survival rates in Europe - BASO ~ The Association For Cancer Surgery
Read report.. Cancer survival is a key measure of the effectiveness of healthcare systems. EUROCARE - the largest cooperative study of population-based cancer survival in Europe - has shown persistent differences between countries for cancer survival, although in general, cancer survival is improving. Major changes in cancer diagnosis, treatment and rehabilitation occurred in the early 2000s. EUROCARE-5 assesses their effect on cancer survival in 29 European countries.. ...
Cancer survival in Scotland: does geography matter? :: SLS - Scottish Longitudinal Study Development & Support UnitCancer survival in Scotland: does geography matter? :: SLS - Scottish Longitudinal Study Development & Support Unit
Scotland has the lowest life expectancy in Western Europe, the slowest rate of health improvement in Europe and wide health inequalities (Hanlon, Lawder et al. 2005). Previous research has demonstrated that Scottish cancer survival rates are similarly poor; for example, Gatta, Ciccolallo et al. (2006) found that cancer survival rates for Scottish women were the lowest in Europe and for men they were in the bottom four. In addition to deprivation, one of the many possible influences on health relates to access to services. This research will use individual level data provided by the Scottish Longitudinal Studies (SLS) to explore cancer survival in the Scottish context using survival analysis techniques. The analysis will examine whether cancer survival is predicted by levels of deprivation (individual and area), access and proximity to health services and the level of remoteness of the area of residence.. This research is different from Sharpe, McMahon et al. (2014) recent work which has focused ...
Blog Archives - Multiple Myeloma - Survival Rate Statistics by HospitalBlog Archives - Multiple Myeloma - Survival Rate Statistics by Hospital
One thing I have found is that the best myeloma centers have a far better 1 year survival rate than the average center which provides data to the National Cancer Institute. Some of the best centers report 1 year relative survival of between the mid to high 90%s. And as I had reported before, the survival rate improves with each year that your live. You can see that analysis if you just CLICK HERE. So, I would hope and pray that the 4 year survival for patients who were diagnosed in 2009 will also show a 19% improvement over the recent 4 year survival rate. Maybe, the entire health care system is just slow in digesting the newest and most effective myeloma treatments, and as a result the ones that are receiving the best care, or second opinions from a myeloma expert are just too small a component of the total myeloma patient population to make a dent in the numbers. This will not change until these best methods spread through osmosis throughout the health care system. What I dont understand is ...
Cancer Survival Rate and Life ExpectancyCancer Survival Rate and Life Expectancy
... - Hear the words stage 4 cancer then we will directly think about death. On the other hand the number of patients of certain cancers is also increased as our society. Cancer will make someone sell their property for treatment of the cancer.
Ovarian cancer survival rates targeted in new campaign.Ovarian cancer survival rates targeted in new campaign.
Low ovarian cancer survival rates are being targeted in a sweeping reform of research into the disease in Australia as new subgroups have been identified.
Long-term clinical outcomes and analyses of atezolizumab for mTNBC. Long-term clinical outcomes and analyses of atezolizumab...Long-term clinical outcomes and analyses of atezolizumab for mTNBC. Long-term clinical outcomes and analyses of atezolizumab...
If you look at the third point, overall survival, the median overall survival in this study was 9.3 months at a follow-up for 15 months. The [?? 4:24] overall survival rates were 41% in one year, 22% at two years and three years which again suggests that there is a form of tail as we have seen in other diseases.. What we analysed then was survival, depending on whether patients had a benefit of this treatment or not. As you can see in green, those patients who had a complete or partial response on the left according to RECIST, on the right to IR RECIST. All patients were still alive at the time of the analysis with 100% one year and 100% two year overall survival rates. If you look on the left side patients with stable disease one year overall survival was 69%, patients with progressive disease one year overall survival was 33%. Of interest, if you look on the left side you see two year overall survival 11% and three year overall survival 11%. These were patients who had pseudoprogression. ...
Is It Dumb to Bring Up U.S. Life Expectancy? - The AtlanticIs It Dumb to Bring Up U.S. Life Expectancy? - The Atlantic
A study published in Lancet Oncology in 2007 calculates cancer survival rates for both men and women in the United States, the United Kingdom, and the European Union as a whole. The study claims that the most important determinants of cancer survival are early diagnosis, early treatment, and access to the best drugs, and that the United States does very well on all three criteria. Early diagnosis helps survival, but it may also distort the comparisons of five or even ten-year survival rates. In any case, the calculated five-year survival rates are much better in the US: they are about 65% for both men and women, while they are much lower in the other countries, especially for men. These apparent advantages in cancer survival rates are large enough to be worth a lot to persons having access to the American health system.. ...
Survival Analysis In R TutorialSurvival Analysis In R Tutorial
Survival Analysis with R bioconnector.org. Introduction. Survival analysis is generally defined as a set of methods for analyzing data where the outcome variable is the time until the occurrence of an event of, Introduction. Survival analysis is generally defined as a set of methods for analyzing data where the outcome variable is the time until the occurrence of an event of. • D. R. Cox and D. Oakes, Analysis of Survival Data, Chapman and Hall, 1984. Introduction to Survival Analysis 4 2. The Nature of Survival Data: Censoring 25/04/2009В В· Censoring in Clinical Trials: Review of Survival Analysis Techniques. J R Stat Soc Series B Stat Methodol. 1972; 34:216вЂ"7. 8. Grambsch PM, Therneau TM.. A Step-by-Step Guide to Survival Analysis Lida Gharibvand, University of California, Riverside ABSTRACT Survival analysis involves the modeling of time-to-event data In the current tutorial, Survival analysis refers to methods for the analysis of data in which the The output from the R analysis ...
Cancer Survival Rates Improve, Researchers Say - The Endoscopy CenterCancer Survival Rates Improve, Researchers Say - The Endoscopy Center
Many five-year survival rates increased among both blacks and whites, but racial disparities have increased in prostate cancer and female breast cancer. "We still have a lot of work to do to understand the causes of these differences, but certainly differences in the kinds and timing of recommended treatments are likely to play a role," said Dr. Lynne Penberthy, associate director of the U.S. National Cancer Institutes Surveillance Research Program ...
Cancer Survival Rates Improve, Researchers Say - Schuylkill Endoscopy CenterCancer Survival Rates Improve, Researchers Say - Schuylkill Endoscopy Center
Many five-year survival rates increased among both blacks and whites, but racial disparities have increased in prostate cancer and female breast cancer. "We still have a lot of work to do to understand the causes of these differences, but certainly differences in the kinds and timing of recommended treatments are likely to play a role," said Dr. Lynne Penberthy, associate director of the U.S. National Cancer Institutes Surveillance Research Program ...
Cancer Survival Rates Improve, Researchers Say - Thunderbird Endoscopy CenterCancer Survival Rates Improve, Researchers Say - Thunderbird Endoscopy Center
Many five-year survival rates increased among both blacks and whites, but racial disparities have increased in prostate cancer and female breast cancer. "We still have a lot of work to do to understand the causes of these differences, but certainly differences in the kinds and timing of recommended treatments are likely to play a role," said Dr. Lynne Penberthy, associate director of the U.S. National Cancer Institutes Surveillance Research Program ...
Thyroid Cancer Survival Rates, by Type and StageThyroid Cancer Survival Rates, by Type and Stage
Survival rates of thyroid cancer are based on outcomes of people whove had the disease. Find the survival rates for thyroid cancer here.
Effect of cimetidine on cumulative survival rates in th | Open-iEffect of cimetidine on cumulative survival rates in th | Open-i
Effect of cimetidine on cumulative survival rates in the colorectal cancer patients. The tumour tissues from individual patients obtained during curative operat
Skin Tumors - Mammary - DR. JULIUS LIPTAKSkin Tumors - Mammary - DR. JULIUS LIPTAK
Prognostic factors associated with clinical presentation include the number of tumors, presence of ulceration, and fixation of tumors to underlying tissue. Survival outcome is significantly worse for dogs with ulcerated mammary carcinomas with a median survival time of 118 days and 1- and 2-year survival rates of 10.8% and 5.4%, respectively, compared to a median survival time of 443 days and 1- and 2-year survival rates of 52.6% and 45.0%, respectively, for dogs with non-ulcerated mammary carcinomas.. The use of desmopressin in the perioperative period significantly improves median survival times in dogs with grade II and III mammary carcinomas. In one prospective study of 18 dogs treated with desmopressin and 10 dogs treated with a saline placebo, the overall median survival time was significantly longer in dogs treated with desmopressin (809 days) compared to dogs in the placebo group (237 days) with 17% and 80% of dogs dying because of disease-related reasons in each group, respectively. ...
4822.0.55.001 - Cancer in Australia: A Snapshot, 2004-054822.0.55.001 - Cancer in Australia: A Snapshot, 2004-05
During 1992-97, the five-year relative survival proportions for all cancers for females (63%) were higher than those for males (57%). For cancer of the kidney, the five year survival rate was similar for males and females (60% and 58% respectively). Differences in survival rates between males and females were observed for people diagnosed with cancer of the bladder (71% and 65% respectively). The greatest difference in five year survival rates was experienced by people with Thyroid cancer with women having higher survival rates than men (96% and 88% respectively). There were similar five year survival rates for people with Hodgkins Lymphoma (males 83% and females 84%) while for people with Leukaemia there was a slightly higher survival rate for women (43%) than for men (41%) (AIHW 2001). ...
4822.0.55.001 - Cancer in Australia: A Snapshot, 2004-054822.0.55.001 - Cancer in Australia: A Snapshot, 2004-05
During 1992-97, the five-year relative survival proportions for all cancers for females (63%) were higher than those for males (57%). For cancer of the kidney, the five year survival rate was similar for males and females (60% and 58% respectively). Differences in survival rates between males and females were observed for people diagnosed with cancer of the bladder (71% and 65% respectively). The greatest difference in five year survival rates was experienced by people with Thyroid cancer with women having higher survival rates than men (96% and 88% respectively). There were similar five year survival rates for people with Hodgkins Lymphoma (males 83% and females 84%) while for people with Leukaemia there was a slightly higher survival rate for women (43%) than for men (41%) (AIHW 2001). ...
Disparities Seen in Breast Cancer Survival Rates : NPRDisparities Seen in Breast Cancer Survival Rates : NPR
A study published in this weeks Journal of the American Medical Association suggests that black women with breast cancer have shorter survival rates due to a higher incidence of other illnesses, such as diabetes and hypertension.
Althouse: Under the new mammogram guidelines, billions of dollars will be saved.Althouse: Under the new mammogram guidelines, "billions of dollars will be saved."
Unfortunately, survival rates are a bad way of evaluating the effectiveness of screening. Two biases (lead time bias, and length bias) occur when the evaluation of screening is done based on survival rates. Survival rates can appear better when 1) disease is diagnosed earlier by screening, even if treatment is not effective or harmful simply because the patient is aware of the diagnosis for a longer period of time than they would have been otherwise (i.e. lead time bias), and 2) periodic screening is more likely to detect slow growing tumors that are less aggressive and take longer, or will never, cause symptoms and death (i.e. length bias). Again, survival can appear better with screening than without screening even if the treatment is ineffective, or is harmful. ...
Myeloma - How To GREATLY Improve The High Risk Myeloma Survival Rate! - Multiple Myeloma - Survival Rate Statistics by HospitalMyeloma - How To GREATLY Improve The High Risk Myeloma Survival Rate! - Multiple Myeloma - Survival Rate Statistics by Hospital
Recently, members of the CIMBCR conducted a retrospective study of high and low risk patients, and obtained some outstanding incites into improved survival for patients with high risk genetic features. Between 2008 and 2012, 715 patients with multiple myeloma identified by FISH and/or cytogenetic data with upfront auto, HCT were identified in the Center for International Blood and Marrow Transplant Research database. HRM(high risk myeloma) was defined as del17p, t(4;14), t(14;16), hypodiploidy (,45 chromosomes excluding -Y) or chromosome 1p and 1q abnormalities; all others were non-HRM. The most significant finding was that HRM patients who had post transplant consolidation or maintenance had a 3 year overall survival rate of 81% versus just 48% for those without post transplant treatment. So HRM patients are 2.7 times more likely to die in three years if they do not have post transplant treatment. You can view the study if you CLICK HERE. ...
Most recent papers with the keyword survival improvement in patients with pancreatic cancer | Read by QxMDMost recent papers with the keyword survival improvement in patients with pancreatic cancer | Read by QxMD
Pancreatic cancer is known to be the deadliest of all common cancers. Despite all efforts in pancreatic cancer treatment, the five-year survival rates at diagnosis over the past 20 years have only increased from 5% to 8%. Assuming that pancreatic cancer is going to become the second most frequent cause of cancer related death in the next 20 years, we are all encouraged to treat patients in clinical trials to gain improvements in this devastating disease. Areas covered: This review will provide a summary of pancreatic cancer treatment over the last 20 years, starting with the pivotal study in 1997 which showed the superiority of gemcitabine over 5-FU in advanced pancreatic cancer and is marked as the beginning of a new era in pancreatic cancer treatment ...
AACR 2016: Five-year survival rates for nivolumab-treated metastatic melanoma patients much higher than historical ratesAACR 2016: Five-year survival rates for nivolumab-treated metastatic melanoma patients much higher than historical rates
The median age of the patients was 61 years, and 67 percent were male.. Data from this trial, which were published in the Journal of Clinical Oncology in 2014, showed that some patients had durable responses that persisted even after discontinuation of the treatment.. The investigators followed the 107 patients for up to five years (with a minimum of 45 months of follow-up) from the time a patient received his or her first dose of nivolumab, and calculated overall survival (OS), reported at AACR.. "The five-year OS in all 107 patients was 34 percent, and OS rates appeared to plateau at around 48 months, which is indicative of long-term benefit in some patients, although more follow-up is needed to fully appreciate the benefit of nivolumab monotherapy," Hodi said.. Survival rates were similar for the 17 patients who received the 3mg/kg dose and the remaining 90 patients who received one of the other doses (0.1 mg, 0.3 mg, 1 mg, and 10 mg nivolumab/kg), he said.. At 12 months, the OS in patients ...
Increase in survival rates in Wales · Pancreatic Cancer ActionIncrease in survival rates in Wales · Pancreatic Cancer Action
Newly-published statistics from Public Health Wales show an increase in pancreatic cancer survival rates in both survival rates at 1 and 5 years.
Breast cancer survival by size and nodal status in Australia, Table of contents - Australian Institute of Health and WelfareBreast cancer survival by size and nodal status in Australia, Table of contents - Australian Institute of Health and Welfare
Breast cancer survival by size and nodal status provides relative survival data up to nine years after diagnosis for women diagnosed in Australia with breast cancer in 1997. There are breakdowns of survival proportions by size of cancer, nodal status, geographic region and socioeconomic status.. ...
Cancer survival rates still vary says charity - NHSCancer survival rates still vary says charity - NHS
Survival rates have risen dramatically for many types of cancer but have hardly improved for others, BBC News reported. Citing new figures released by the cancer charity Macmillan...
The Top 15 Lies Youre Being Told About Health and Mainstream Medicine ~ HealthyAeonThe Top 15 Lies You're Being Told About Health and Mainstream Medicine ~ HealthyAeon
The reason a 5-year relative survival rate is the standard used to assess mortality rates is due to most cancer patients going downhill after this period. Its exceptionally bad for business and the cancer industry knows it. They could never show the public the true 97% statistical failure rate in treating long-term metastatic cancers. If they did publish the long-term statistics for all cancers administered cytotoxic chemotherapy, that is 10+ years and produced the objective data on rigorous evaluations including the cost-effectiveness, impact on the immune system, quality of life, morbidity and mortality, it would be very clear to the world that chemotherapy makes little to no contribution to cancer survival at all. No such study has ever been conducted by independent investigators in the history of chemotherapy. The only studies available come from industry funded institutions and scientists and none of them have ever inclusively quantified the above variables ...
Cancer Survival Rates Improve in WalesCancer Survival Rates Improve in Wales
The survival rate for all cancers for people living in Wales is continuing to increase, according to the latest official statistics.
Improvement in child cancer survival rates threatened by lack of new drug development - Healthcanal.com : Healthcanal.comImprovement in child cancer survival rates threatened by lack of new drug development - Healthcanal.com : Healthcanal.com
In high-income countries, we have nearly reached optimisation of present anticancer treatments," says Professor Kathy Pritchard-Jones.. "New regulatory approval and research strategies are urgently needed to speed the development of new, effective, and safer treatments for children with cancer if we are to continue to improve the cure rate, reduce toxicity compared to existing treatments, and minimise side effects in later life," she continues.. Although more children and young people in high-income countries are surviving cancer than ever before, cancer remains the leading cause of death from disease in children aged 1 to 15 years. More than 5,000 children still lose their lives to cancer every year in these regions.. Increased participation in international, collaborative clinical trials has successfully raised survival from 30% to 80% over the last half century. "But an increasingly complex and strict regulatory environment for clinical research and data sharing is limiting childrens access ...
Press Release - January 6, 2017 - Pancreatic Cancer Survival Increases to 9 Percent - Pancreatic Cancer Action NetworkPress Release - January 6, 2017 - Pancreatic Cancer Survival Increases to 9 Percent - Pancreatic Cancer Action Network
The five-year survival rate for the disease increased, moving from 8 to 9 percent.* This is the third straight year that the five-year survival rate has climbed.. "This moderate but critical shift highlights that we are making progress and that we need to continue to accelerate our efforts," said Julie Fleshman, JD, MBA, president and CEO of the Pancreatic Cancer Action Network. "I am extremely grateful to our supporters and the amazing patients that participate in clinical trials helping to make this progress possible.". While there are successes to celebrate, there is much work to be done for patients today, and for those who will be diagnosed in 2017. It is estimated that 53,670 Americans will be diagnosed this year and 43,090 people will die from the disease.. Pancreatic cancer remains the third leading cause of cancer-related death in the United States, killing more people than breast cancer. The disease is projected to become the second leading cause of cancer-related death around ...
Comparison of continuous versus categorical tumor measurement-based metrics to predict overall survival in cancer treatment...Comparison of continuous versus categorical tumor measurement-based metrics to predict overall survival in cancer treatment...
TY - JOUR. T1 - Comparison of continuous versus categorical tumor measurement-based metrics to predict overall survival in cancer treatment trials. AU - An, Ming Wen. AU - Mandrekar, Sumithra J. AU - Branda, Megan E.. AU - Hillman, Shauna L.. AU - Adjei, Alex. AU - Pitot, Henry Clement. AU - Goldberg, Richard M.. AU - Sargent, Daniel J.. PY - 2011/10/15. Y1 - 2011/10/15. N2 - Purpose: The categorical definition of response assessed via the Response Evaluation Criteria in Solid Tumors has documented limitations. We sought to identify alternative metrics for tumor response that improve prediction of overall survival. Experimental Design: Individual patient data from three North Central Cancer Treatment Group trials (N0026, n = 117; N9741, n = 1,109; and N9841, n = 332) were used. Continuous metrics of tumor size based on longitudinal tumor measurements were considered in addition to a trichotomized response [TriTR: response (complete or partial) vs. stable disease vs. progression). Cox ...
Prostate cancer survival rates very high regardless of treatment, study finds - AOL UK LivingProstate cancer survival rates very high regardless of treatment, study finds - AOL UK Living
Regular monitoring of prostate cancer as a treatment option offers the same chances of survival 10 years after diagnosis as surgery or radiotherapy, a major study into the disease has discovered.The decade-long trial, which examined men with localised
Cancer survival rates hit by long waiting lists | Daily Mail OnlineCancer survival rates hit by long waiting lists | Daily Mail Online
Long waits for radiotherapy across the UK are hitting cancer patients' chances of survival. According to a paper published in the British Medical Journal, many units providing radiotherapy are overstretched with long delays for patients awaiting treatment
Progesterone may improve breast cancer survival rates - ONAProgesterone may improve breast cancer survival rates - ONA
Receptors that mediate activity of the female sex hormones (estrogen and progesterone) interact with DNA to control the growth of a large majority of breast cancers, research indicates.
Stage Iv Kidney Cancer Survival Rate 2019 • Kidney TreatmentStage Iv Kidney Cancer Survival Rate 2019 • Kidney Treatment
Stage IV Ovarian Cancer. Stage IV (any T, any N, M1) is the most advanced stage of ovarian cancer. In this stage the cancer has spread to the inside of
New investigation reveals new landscape gardening businesses have an average survival rate of 87%New investigation reveals new landscape gardening businesses have an average survival rate of 87%
Confused.coms investigation revealed that landscape gardeners have an average survival rate of 87%. With the top five locations being Sheffield (100%)...
Married patients with heart disease have better survival rates - Healthcanal.com : Healthcanal.comMarried patients with heart disease have better survival rates - Healthcanal.com : Healthcanal.com
Marriage is a vital factor affecting the survival of patients who have had a heart attack, as well as the survival of patients with the most important risk factors
Edgycater: Will Cancer Survival Rate Be A Casualty of ObamaCare?Edgycater: Will Cancer Survival Rate Be A Casualty of ObamaCare?
Health care rationing kills and does so in the most cruel way. A person is diagnosed with an illness that requires radical and expensive treatment. A pencil-necked geek representing the Kremlin on the Potomac tells the person that the federal treatment matrix shows they fall outside the qualifications for treatment. They are too old. The odds for survival are too low to risk the money. All the allocated money for the procedure in a given year has been spent. "Go see one of our End-of-Life Counselors to plan your final demise. By the way, if you want to be a real patriot you will swallow this arsenic capsule and we can cancel your other medications immediately ...
Disease-free survival curve (A) and overall survival cu | Open-iDisease-free survival curve (A) and overall survival cu | Open-i
Disease-free survival curve (A) and overall survival curve (B) according to CD44s protein expression. CD44s expression correlates with a negative prognosis (A),
Social isolation may lead to poor survival rates in breast cancer patientsSocial isolation may lead to poor survival rates in breast cancer patients
New research suggests that socially isolated breast cancer survivors have higher rates of recurrence and mortality compared with socially integrated women.
SurvivalSurvival
... measures the share of people diagnosed with cancer in a certain year and who are still alive after a certain period of time (usually measured as 1-year and 5-year survival).. In Europe, there have been continuous increases in 5-year survival rates for the most common cancer types in all countries. These improvements are driven by a number of factors, including effective prevention and screening programmes as well as advances in diagnostics and surgical techniques. In addition, a recent step-change in treatment (with three distinct periods over the past two decades with particularly high numbers of new treatments being approved) has paved the way for further improvements in cancer outcomes.. However, variation in cancer outcomes continue to persist. In colon cancer, for instance, if every European country were to achieve the survival rates of the best performing country - Iceland - then an additional 15,706 people across Europe would survive at least five years following ...
The NHS Sucks: Cancer Survival Rates - A Post Code LotteryThe NHS Sucks: Cancer Survival Rates - A Post Code Lottery
I am 56 and currently fighting a battle with lung cancer. I originally started this blog to record my experiences of lung cancer and the treatments involved. I hoped others in a similar position might find it useful. However, due to problems with the DWP who tried to make my life difficult, at a time I could well do without it, I stumbled upon some very startling evidence of the scale of corruption in this country and the EU. The MPs Expenses scandal is just the tip of the iceburg, BILLIONS OF POUNDS have gone missing without trace via the EU and no serious effort has been made to trace it. Although I dont expect to live for much longer I feel I owe it to my children and grandchildren to do everything I can to share this information with as many others as possible. And I ask anybody who found their way here to do the same. If you follow the links on the various blogs I have set up here, there are 16 to date, (These can be found by scrolling down the page and clicking on MY PROFILE} Im sure ...
Expression of Proteins Linked to Poor Outcome in Women with Ovarian Cancer | Libbys H*O*P*E*Expression of Proteins Linked to Poor Outcome in Women with Ovarian Cancer | Libby's H*O*P*E*
Scientists have established the presence of certain proteins in ovarian cancer tissues and have linked these proteins to poor survival rates in women with advanced stages of the disease. Scientists have established the presence of certain proteins in ovarian cancer tissues and have linked these proteins to poor survival rates in women with advanced stages…
Survival rate for ovarian cancer stage 3a. Survival Rates for Ovarian Cancer, by StageSurvival rate for ovarian cancer stage 3a. Survival Rates for Ovarian Cancer, by Stage
Recurrent Ovary Cancer: Signs/Symptoms, Statistics And Risks Of Ovarian Cancer Coming Back, Treatment Options, Cure Chances Scientific research and modern technology have improved the Whipple procedure survival rate knowing truth somehow save your health ultimately life if healthier than yesterday.
Regular Prostate Exams Lead To Early Detection, Better Survival RatesRegular Prostate Exams Lead To Early Detection, Better Survival Rates
A new study has found that regular screenings for prostate cancer cut the risk of dying from the disease in half, according to Lancet Oncology. This is because patients who may develop prostate cancer will be more likely to be diagnosed earlier and begin treatment sooner.. In an effort to determine how much regular screenings increased mortality rates linked to the illness, more than 20,000 men who were born between 1930 and 1944 were split into two groups. Every two years, the first group would visit a physician and undergo a prostate exam and were compared to the control group.. After 14 years of follow-ups, the results of the study showed that in the screening group 11.4 percent of cancer cases were diagnosed, while 7.2 percent were detected in the control group. Also, of the patients who developed prostate cancer, 231 were diagnosed during the first round of screenings, while 665 cases were discovered during several rounds of exams.. These findings could prove that annual screenings can lead ...
Vauxhall CavalierVauxhall Cavalier
Vauxhall ChevetteVauxhall Chevette
Hepatocellular carcinomaHepatocellular carcinoma
Testicular cancerTesticular cancer
Hand transplantationHand transplantation
Non-small-cell lung carcinomaNon-small-cell lung carcinoma
Mary ClydeMary Clyde
African horse sicknessAfrican horse sickness
Carolina wrenCarolina wren
LeukemiaLeukemia
Fetal viabilityFetal viability
20302030
DefaunationDefaunation
Banksia browniiBanksia brownii
Marine shrimp farmingMarine shrimp farming
Wil DasovichWil Dasovich
Campbell albatrossCampbell albatross
Evangelos KatsioulisEvangelos Katsioulis
Childrens Cancer InstituteChildren's Cancer Institute
Fianarantsoa ProvinceFianarantsoa Province
Small intestine cancerSmall intestine cancer
Patara Elephant FarmPatara Elephant Farm
Extermination campExtermination camp
Ankle replacementAnkle replacement
Dilated cardiomyopathyDilated cardiomyopathy
Equine proximal enteritisEquine proximal enteritis
North American PiedmonteseNorth American Piedmontese
Mitral valve replacementMitral valve replacement
Pancreatic Cancer ActionPancreatic Cancer Action
FinnsheepFinnsheep
T细胞 - 维基百科，自由的百科全书T细胞 - 维基百科，自由的百科全书
Eurasian magpieEurasian magpie
Saint Barnabas Medical CenterSaint Barnabas Medical Center
Streptococcus pneumoniaeStreptococcus pneumoniae
EbolaEbola
Cushings diseaseCushing's disease
MedicaidMedicaid
MallardMallard
PaleolithicPaleolithic
Black wildebeestBlack wildebeest
Health in NepalHealth in Nepal
Hematopoietic stem cell transplantationHematopoietic stem cell transplantation
Caulobacter crescentusCaulobacter crescentus
Internet of thingsInternet of things
TornadoTornado
PAX8PAX8
DiagenesisDiagenesis
AnglingAngling
Holocene extinctionHolocene extinction
InhalationInhalation
Thyroglossal cystThyroglossal cyst
PoodlePoodle
Brain tumorBrain tumor
Lassa feverLassa fever
BrassicaceaeBrassicaceae
Bengal famine of 1943Bengal famine of 1943
InbreedingInbreeding
WhaleWhale
PleiotropyPleiotropy
ReptileReptile
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
Survival RateCell SurvivalDisease-Free SurvivalSurvival AnalysisTreatment OutcomeSurvivalGraft SurvivalRetrospective StudiesPrognosisKaplan-Meier EstimateNeoplasm StagingFollow-Up StudiesTime FactorsCombined Modality TherapyProportional Hazards ModelsAntineoplastic Combined Chemotherapy ProtocolsNeoplasm Recurrence, LocalLung NeoplasmsLiver NeoplasmsMultivariate AnalysisAdenocarcinomaLymphatic MetastasisActuarial AnalysisRisk FactorsChemotherapy, AdjuvantProspective StudiesTumor Markers, BiologicalAntineoplastic AgentsLiver TransplantationApoptosisCisplatinCarcinoma, HepatocellularCarcinoma, Squamous CellNeoplasm MetastasisBreast NeoplasmsAge FactorsImmunohistochemistryCohort StudiesPostoperative ComplicationsRecurrenceHepatectomyRegistriesRadiotherapy, AdjuvantStomach NeoplasmsDisease ProgressionCarcinoma, Non-Small-Cell LungDoxorubicinVincristineCyclophosphamideReoperationFluorouracilNeoplasm InvasivenessKidney TransplantationCell Line, TumorBrain NeoplasmsPancreatic NeoplasmsRadiotherapy DosageRisk AssessmentDrug Administration ScheduleLife TablesEsophageal NeoplasmsRemission InductionGraft RejectionCarcinomaColorectal NeoplasmsLymph Node ExcisionPredictive Value of TestsSignal TransductionTransplantation, HomologousMice, Inbred C57BLGastrectomyNeoadjuvant TherapyNeoplasmsPrednisoneIncidenceDisease Models, AnimalEtoposideBile Duct NeoplasmsChemoembolization, TherapeuticTissue DonorsCell ProliferationBone NeoplasmsCardiopulmonary ResuscitationSEER ProgramRectal NeoplasmsHeart ArrestJapanSalvage TherapySarcomaGene Expression Regulation, NeoplasticRadiotherapyImmunosuppressive AgentsChi-Square DistributionCholangiocarcinomaDose FractionationCryopreservationMelanomaMice, Inbred BALB CDeoxycytidineCells, CulturedCause of DeathOvarian NeoplasmsChemoradiotherapyPatient SelectionHead and Neck NeoplasmsDose-Response Relationship, DrugProbabilityAntimetabolites, AntineoplasticTissue SurvivalVinblastineKidney NeoplasmsTreatment FailureProsthesis FailureInfant, NewbornLiving DonorsMutationCarboplatinAnalysis of VariancePneumonectomyOsteosarcomaEsophagectomyReverse Transcriptase Polymerase Chain ReactionPalliative CarePaclitaxelMethotrexateKidney Failure, ChronicBile Ducts, IntrahepaticRadiotherapy, High-EnergyGlioblastomaNasopharyngeal NeoplasmsNeoplasm GradingUnited StatesLymphoma, Non-HodgkinMice, KnockoutBrachytherapySurvivorsSex FactorsBleomycinMicrobial ViabilityLiver FailurePancreas TransplantationProstatic NeoplasmsCarcinoma, Small CellPreoperative CareSeverity of Illness IndexAntibodies, MonoclonalTumor BurdenCryoprotective AgentsHeart TransplantationRNA, MessengerTransplantation, AutologousSkin NeoplasmsBlotting, WesternColonic NeoplasmsProsthesis DesignLymph NodesClinical Trials as TopicCarcinoma, Renal CellDacarbazineRegression AnalysisCytarabineMouth NeoplasmsCadaverGliomaLongevityGene Expression ProfilingDrug Resistance, NeoplasmSurvival of Motor Neuron 1 ProteinSoft Tissue NeoplasmsIfosfamideHodgkin DiseaseProto-Oncogene ProteinsHematopoietic Stem Cell TransplantationInfusions, IntravenousAcute DiseaseMultiple MyelomaPancreatectomyTumor Suppressor Protein p53Precursor Cell Lymphoblastic Leukemia-LymphomaTomography, X-Ray ComputedMice, TransgenicLeucovorinPostoperative CareRenal DialysisTaxoidsNeoplasm ProteinsCell DeathPregnancyOut-of-Hospital Cardiac Arrestalpha-FetoproteinsBone Marrow TransplantationLymphoma, Large B-Cell, DiffuseDose-Response Relationship, RadiationEthylene GlycolVitrificationRandomized Controlled Trials as TopicLeukemia, Myeloid, AcuteAntineoplastic Agents, AlkylatingStatistics, NonparametricFranceSepsis
UK cancer survival rate lowest in Europe - TelegraphUK cancer survival rate lowest in Europe - Telegraph
Cancer survival rates are upCancer survival rates are up
Cancer survival rate: can increase the anxiety | merinewsCancer survival rate: can increase the anxiety | merinews
What Factors Impact The Pancreatic Cancer Survival Rate? - CancerWhat Factors Impact The Pancreatic Cancer Survival Rate? - Cancer
5-Year Survival Rate | CureSearch5-Year Survival Rate | CureSearch
Nanoinjection increases survival rate of cellsNanoinjection increases survival rate of cells
Cardiac arrest survival rate in Napa County twice national average | Local News | napavalleyregister.comCardiac arrest survival rate in Napa County twice national average | Local News | napavalleyregister.com
Cancer survival rates to skyrocket: study | Sky News AustraliaCancer survival rates to skyrocket: study | Sky News Australia
Businesses have higher survival rates in remote areas, survey showsBusinesses have higher survival rates in remote areas, survey shows
Pembrolizumab Long-Term Survival Rate Could Reach 25% in NSCLCPembrolizumab Long-Term Survival Rate Could Reach 25% in NSCLC
survival rates : Counsel & Healsurvival rates : Counsel & Heal
As cancer survival rate grows, so does number of new casesAs cancer survival rate grows, so does number of new cases
Colon Cancer Causes, Treatment, Symptoms & Survival RateColon Cancer Causes, Treatment, Symptoms & Survival Rate
Carcinoid Syndrome (Tumor) Symptoms, Prognosis, Survival RateCarcinoid Syndrome (Tumor) Symptoms, Prognosis, Survival Rate
Early HIV treatment boosts infant survival rate | New ScientistEarly HIV treatment boosts infant survival rate | New Scientist
Eye Cancer Survival RatesEye Cancer Survival Rates
Survival Rates for OsteosarcomaSurvival Rates for Osteosarcoma
Cancer survival rates - NHSCancer survival rates - NHS
Bone cancer: Survival rate, causes, types, and treatmentBone cancer: Survival rate, causes, types, and treatment
Stage 4 melanoma: Survival rate, pictures, and treatmentStage 4 melanoma: Survival rate, pictures, and treatment
Meningioma Survival Rate | MoffittMeningioma Survival Rate | Moffitt
Survival Are Rates Now Better - RedorbitSurvival Are Rates Now Better - Redorbit
Neuroendocrine Tumor Survival Rate | MoffittNeuroendocrine Tumor Survival Rate | Moffitt
Survival rate - WikipediaSurvival rate - Wikipedia
Cannabis Combo Therapy Triples Pancreatic Cancer Survival RateCannabis Combo Therapy Triples Pancreatic Cancer Survival Rate
Cancer survival rates increase: StatsCan | National PostCancer survival rates increase: StatsCan | National Post
Leukemia: Survival Rates and PrognosisLeukemia: Survival Rates and Prognosis
survival rates Archives - FactCheck.orgsurvival rates Archives - FactCheck.org
Differing cancer survival rates | Health24Differing cancer survival rates | Health24
Mesothelioma Survival Rate | Mesothelioma Resource OnlineMesothelioma Survival Rate | Mesothelioma Resource Online
Disparities Seen in Breast Cancer Survival Rates : NPRDisparities Seen in Breast Cancer Survival Rates : NPR
What are the survival rates for Reye syndrome?What are the survival rates for Reye syndrome?
Cancer survival rates still vary says charity - NHSCancer survival rates still vary says charity - NHS
Study Suggests CT Scans Improve Survival Rates - RedorbitStudy Suggests CT Scans Improve Survival Rates - Redorbit
What are the survival rates for ocular lymphoma?What are the survival rates for ocular lymphoma?
Food survival books, the survival rated r usFood survival books, the survival rated r us
Misconceptions About Prostate Cancer Survival RatesMisconceptions About Prostate Cancer Survival Rates
Does Attitude Help Cancer Survival Rates?Does Attitude Help Cancer Survival Rates?
CPR survival rates are lower than most people think | ReutersCPR survival rates are lower than most people think | Reuters
Improved Treatment Raises Medulloblastoma Survival Rate | EmaxHealthImproved Treatment Raises Medulloblastoma Survival Rate | EmaxHealth
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
Survival RateCell SurvivalDisease-Free SurvivalSurvival AnalysisTreatment OutcomeSurvivalGraft SurvivalRetrospective StudiesPrognosisKaplan-Meier EstimateNeoplasm StagingFollow-Up StudiesTime FactorsCombined Modality TherapyProportional Hazards ModelsAntineoplastic Combined Chemotherapy ProtocolsNeoplasm Recurrence, LocalLung NeoplasmsLiver NeoplasmsMultivariate AnalysisAdenocarcinomaLymphatic MetastasisActuarial AnalysisRisk FactorsChemotherapy, AdjuvantProspective StudiesTumor Markers, BiologicalAntineoplastic AgentsLiver TransplantationApoptosisCisplatinCarcinoma, HepatocellularCarcinoma, Squamous CellNeoplasm MetastasisBreast NeoplasmsAge FactorsImmunohistochemistryCohort StudiesPostoperative ComplicationsRecurrenceHepatectomyRegistriesRadiotherapy, AdjuvantStomach NeoplasmsDisease ProgressionCarcinoma, Non-Small-Cell LungDoxorubicinVincristineCyclophosphamideReoperationFluorouracilNeoplasm InvasivenessKidney TransplantationCell Line, TumorBrain NeoplasmsPancreatic NeoplasmsRadiotherapy DosageRisk AssessmentDrug Administration ScheduleLife TablesEsophageal NeoplasmsRemission InductionGraft RejectionCarcinomaColorectal NeoplasmsLymph Node ExcisionPredictive Value of TestsSignal TransductionTransplantation, HomologousMice, Inbred C57BLGastrectomyNeoadjuvant TherapyNeoplasmsPrednisoneIncidenceDisease Models, AnimalEtoposideBile Duct NeoplasmsChemoembolization, TherapeuticTissue DonorsCell ProliferationBone NeoplasmsCardiopulmonary ResuscitationSEER ProgramRectal NeoplasmsHeart ArrestJapanSalvage TherapySarcomaGene Expression Regulation, NeoplasticRadiotherapyImmunosuppressive AgentsChi-Square DistributionCholangiocarcinomaDose FractionationCryopreservationMelanomaMice, Inbred BALB CDeoxycytidineCells, CulturedCause of DeathOvarian NeoplasmsChemoradiotherapyPatient SelectionHead and Neck NeoplasmsDose-Response Relationship, DrugProbabilityAntimetabolites, AntineoplasticTissue SurvivalVinblastineKidney NeoplasmsTreatment FailureProsthesis FailureInfant, NewbornLiving DonorsMutationCarboplatinAnalysis of VariancePneumonectomyOsteosarcomaEsophagectomyReverse Transcriptase Polymerase Chain ReactionPalliative CarePaclitaxelMethotrexateKidney Failure, ChronicBile Ducts, IntrahepaticRadiotherapy, High-EnergyGlioblastomaNasopharyngeal NeoplasmsNeoplasm GradingUnited StatesLymphoma, Non-HodgkinMice, KnockoutBrachytherapySurvivorsSex FactorsBleomycinMicrobial ViabilityLiver FailurePancreas TransplantationProstatic NeoplasmsCarcinoma, Small CellPreoperative CareSeverity of Illness IndexAntibodies, MonoclonalTumor BurdenCryoprotective AgentsHeart TransplantationRNA, MessengerTransplantation, AutologousSkin NeoplasmsBlotting, WesternColonic NeoplasmsProsthesis DesignLymph NodesClinical Trials as TopicCarcinoma, Renal CellDacarbazineRegression AnalysisCytarabineMouth NeoplasmsCadaverGliomaLongevityGene Expression ProfilingDrug Resistance, NeoplasmSurvival of Motor Neuron 1 ProteinSoft Tissue NeoplasmsIfosfamideHodgkin DiseaseProto-Oncogene ProteinsHematopoietic Stem Cell TransplantationInfusions, IntravenousAcute DiseaseMultiple MyelomaPancreatectomyTumor Suppressor Protein p53Precursor Cell Lymphoblastic Leukemia-LymphomaTomography, X-Ray ComputedMice, TransgenicLeucovorinPostoperative CareRenal DialysisTaxoidsNeoplasm ProteinsCell DeathPregnancyOut-of-Hospital Cardiac Arrestalpha-FetoproteinsBone Marrow TransplantationLymphoma, Large B-Cell, DiffuseDose-Response Relationship, RadiationEthylene GlycolVitrificationRandomized Controlled Trials as TopicLeukemia, Myeloid, AcuteAntineoplastic Agents, AlkylatingStatistics, NonparametricFranceSepsis
CancersPrognosisPancreatic cancer survival rateMortality ratesPatientsDiagnosisImprove survival ratesEsophageal cancer survival2017Lymph nodesChancesLast 40StudyImprovementsYearsTransplantDisparitiesCancer spreads to other organsPeopleLong-term survival ratesChance of survivalAverage survivalOverall survival ratesLife expectancyOutcomesChemotherapyLong-term survivalIncreasing 5-year survival ratesIncidenceImproves survival ratesMortality rateMedian survivalRelative survival ratePancreatic cancer survivalBoost survivalAffect survivalImproveChances of survivalFive-yearPrognosis and survival rateTreatmentEbolaComplication rateAcute lymphoblTypically2000MelanomaPatient survivalSymptomsEstimatesHigherResearchers foundFavorableOvarian cancerPeople diagnosed with cancerPercentProstate cancerAttitude Help Cancer Survival RatesPercentage of peopleLiver
Cancers4
Prognosis1
Pancreatic cancer survival rate2
Mortality rates1
Patients11
Diagnosis2
Improve survival rates1
  • The results would identify a high risk group of people at an early stage, who could then go on to have clinical screening to diagnose and treat oesophageal cancer at a much earlier stage and significantly improve survival rates. (ecancer.org)
Esophageal cancer survival1
20171
  • Matthias Simonis et al, Survival rate of eukaryotic cells following electrophoretic nanoinjection, Scientific Reports (2017). (phys.org)
Lymph nodes3
Chances3
Last 401
  • With only slight changes in life expectancy over the last 40 years and cancer rates on the rise, cancer is an epidemic of the modern world with experts everywhere searching for a solution, synthetic or natural. (cbdorigin.com)
Study5
  • Spain's overall five-year survival rate rose for all types of cancer diagnosed in the decade in question, according to the results of the Concord 2 study published in leading medical journal The Lancet on Wednesday. (thelocal.es)
  • The study of over 25 million people in 67 countries also reveals a large rise in the survival rate for Spanish children suffering from acute lymphoblastic leukaemia. (thelocal.es)
  • Our findings show that in some countries, cancer is far more lethal than in others-in the 21st century there should not be such a dramatic gulf in survival,' said Dr Claudia Allemani, lead study author and Senior Lecturer in Cancer Epidemiology at the London School of Hygiene & Tropical Medicine. (thelocal.es)
  • In the study , researchers found that when using Chemotherapy with CBD for cancer, it inhibited the proliferation rate of cancer cells and tripled the survival rate of mice with pancreatic cancer. (cbdorigin.com)
  • A diet lower in fats could potentially increase the cancer survival rate of overweight children suffering lymphoblastic leukemia, a new study suggests. (childcancersupport.com)
Improvements2
  • Strong improvements were also seen for cancer of the colon and rectum, and for breast cancer, where the survival rate rose from 77.8 percent to 83.7 percent. (thelocal.es)
  • Despite the improvements, the 27.3 percent survival rate from 2005 to 2009 is still a long way below the figure for Japan (54 percent) and Korea (58 percent), where diagnostic activity is more intensive and surgery is more aggressive. (thelocal.es)
Years6
Transplant1
Disparities2
Cancer spreads to other organs1
  • In fact, the stage IV survival rate, wherein the cancer spreads to other organs in the body, is as little as 5 percent. (healthhearty.com)
People6
Long-term survival rates1
Chance of survival1
  • Businesses that are set up outside London have a higher chance of survival than those in the city, according to research from eBay UK. (lsbf.org.uk)
Average survival2
  • In cases where resection can be carried out, only an average survival rate of 23 to 36 months is possible. (sooperarticles.com)
  • He got about the same form of Pca I got[Ductal Cribriform]--nasty---aggressive---with an average survival of 18 months----He retired at age 55 when DX with Pca. (healthunlocked.com)
Overall survival rates1
Life expectancy1
Outcomes8
  • Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they can't predict what will happen in any particular person's case. (cancer.org)
  • Qatar, which has most of the latest technologies for treating cancer, can claim treatment results comparable to the outcomes in western countries regarding survival rate, a top official of Hamad Medical Corporation (HMC) has told Gulf Times. (gulf-times.com)
  • CONCORD-2 Study - demonstrated, the outcomes of the Stem Cell Transplant Programme, as measured by the 100 day post-transplant survival rates of 100% are meeting internationally set benchmarks. (gulf-times.com)
  • SEER specifically collects and publishes cancer incidence and survival data, such as disease type and stage and patient treatment and outcomes. (iran-daily.com)
  • Some seeds do not thrive well when sprouted in different environments, but Home and Garden America's survival seed vault have been proven to deliver impressive outcomes regardless of the sprouting condition. (pr.com)
  • Since then, a whole body of biology has been learned - none of which has been incorporated into patient survival outcomes for women undergoing BCT or a mastectomy. (mdanderson.org)
  • Primary outcomes included disease-free survival and melanoma-specific survival. (facs.org)
  • The exact same analysis showed similar results in survival outcomes. (facs.org)
Chemotherapy11
Long-term survival6
Increasing 5-year survival rates1
Incidence5
Improves survival rates1
Mortality rate7
  • Study results revealed a 25 percent lower mortality rate in the CT group measured on the TRISS scale, and 13 percent less using the RISC index. (redorbit.com)
  • About 38% of hantavirus infections are fatal (mortality rate). (rxlist.com)
  • Fewer than a quarter of the 68 countries targeted by the Millennium Development Goal 4 (reduction of mortality rate in children less than five years old by two-thirds by 2015) are on track to achieve that goal. (wellcome.ac.uk)
  • The effects of the interventions were dramatic: by the second and third years of the trial, the neonatal mortality rate in the areas where the participatory women's groups existed had fallen by 45 per cent. (wellcome.ac.uk)
  • The aggressive measures used by the health care workers in Conakry played a role in keeping the mortality rate relatively low, Fowler said. (foxnews.com)
  • The charity also calculated that a child born in the UK is more than twice as likely to die before the age of five as in Iceland or Luxembourg, with the UK having a child mortality rate of 4.6 per 1,000 births, and the other two countries being 2.1 and two respectively. (express.co.uk)
  • Countries are then ranked on five key factors - risk of maternal death, under-five mortality rate, educational status, economic achievement and political status. (express.co.uk)
Median survival7
Relative survival rate8
Pancreatic cancer survival3
Boost survival2
Affect survival4
Improve13
Chances of survival3
Five-year8
Prognosis and survival rate2
Treatment22
Ebola3
Complication rate1
  • And this is a surgery which has a higher complication rate, so it is somewhat concerning to see that there is no associated survival benefit in our study. (womenshealthmag.com)
Acute lymphobl1
Typically3
20001
  • Before the year 2000, three-year disease specific survival was better in Caucasians than African Americans (79.3 percent versus 75.1 percent, p=0.025). (news-medical.net)
Melanoma2
Patient survival2
  • In addition to asking about general knowledge of CPR and personal experiences with CPR, the researchers presented participants with several scenarios and asked them to estimate the likelihood of CPR success and patient survival in each case. (reuters.com)
  • One of the most important indicators of patient survival rate is tumor location. (mesothelioma.com)
Symptoms2
  • One factor that has a significant effect on survival rates is the latency period between initial asbestos exposure and the appearance of symptoms. (mesotheliomasymptoms.com)
  • Dr Chin-Kuo Chang , lead author of the paper from the IoP at King's says: "We found that people with mental health disorders had worse survival rates than people with no history of mental illness, even though they were not presenting with symptoms of cancer any later than other people. (kcl.ac.uk)
Estimates5
Higher9
Researchers found1
  • Researchers found that when premenopausal survivors were given treatments of Zometa intravenously, the medication actually helped to increase their survival rate - with some doctors saying it ushers in a new " standard of care . (theweek.com)
Favorable1
  • As a result, the survival rate - especially for neuroendocrine tumors that are diagnosed in early stages and properly treated - can be favorable. (moffitt.org)
Ovarian cancer1
  • But if ovarian cancer is diagnosed early, when treatments are not as intensive or long-lasting, it boasts a survival rate of 92 percent. (womensenews.org)
People diagnosed with cancer1
Percent13
Prostate cancer2
Attitude Help Cancer Survival Rates2
Percentage of people1
Liver1
Survival Rate Is Not the Best Way to Judge Cancer Spending | The Law Office Of Gerald Oginski, LLC
Survival Rate Is Not the Best Way to Judge Cancer Spending | The Law Office Of Gerald Oginski, LLC (oginski-law.com)
Cardiac arrest survival rate in Napa County twice national average | Local News | napavalleyregister.com
Cardiac arrest survival rate in Napa County twice national average | Local News | napavalleyregister.com (napavalleyregister.com)
Improved breast cancer survival rates linked to smaller tumors | EurekAlert! Science News
Improved breast cancer survival rates linked to smaller tumors | EurekAlert! Science News (eurekalert.org)
Can You Die from Skin Cancer? Survival Rates and Prevention
Can You Die from Skin Cancer? Survival Rates and Prevention (healthline.com)
Midland TX Oncologist Doctors - Non-Hodgkin's Lymphoma: Types, Treatment, Symptoms , Stages & Survival Rate
Midland TX Oncologist Doctors - Non-Hodgkin's Lymphoma: Types, Treatment, Symptoms , Stages & Survival Rate (medicinenet.com)
What Causes Pancreatic Cancer? Symptoms, Signs & Survival Rate
What Causes Pancreatic Cancer? Symptoms, Signs & Survival Rate (emedicinehealth.com)
Norfolk VA Oncologist Doctors - Breast Cancer: Signs, Symptoms, Causes, Treatment, Stages & Survival Rates
Norfolk VA Oncologist Doctors - Breast Cancer: Signs, Symptoms, Causes, Treatment, Stages & Survival Rates (medicinenet.com)
Zero Hedge | On a long enough timeline the survival rate for everyone drops to zero
Zero Hedge | On a long enough timeline the survival rate for everyone drops to zero (zerohedge.com)
Estimates of the Direct Effect of Seawater pH on the Survival Rate of Species Groups in the California Current Ecosystem
Estimates of the Direct Effect of Seawater pH on the Survival Rate of Species Groups in the California Current Ecosystem (journals.plos.org)
MJA Podcasts 2018 Episode 69: Lymphoma relative survival rates, with Dr Greg Hapgood | Free Podcasts | Podomatic
MJA Podcasts 2018 Episode 69: Lymphoma relative survival rates, with Dr Greg Hapgood | Free Podcasts | Podomatic" (podomatic.com)
PLOS ONE: MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation...
PLOS ONE: MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation... (journals.plos.org)
Lung Cancer Symptoms, Signs, Stages, Treatment & Survival Rate Viewer Comments and Reviews: Lung Cancer - Symptoms and Signs -...
Lung Cancer Symptoms, Signs, Stages, Treatment & Survival Rate Viewer Comments and Reviews: Lung Cancer - Symptoms and Signs -... (emedicinehealth.com)
AIDS Survival Rate Worse - latimes
AIDS Survival Rate Worse - latimes (articles.latimes.com)
Allotransplanted Neurons Used to Repair Peripheral Nerve Injury Do Not Elicit Overt Immunogenicity
Allotransplanted Neurons Used to Repair Peripheral Nerve Injury Do Not Elicit Overt Immunogenicity (journals.plos.org)
Bladder Cancer | Knight Cancer Institute | OHSU
Bladder Cancer | Knight Cancer Institute | OHSU (ohsu.edu)
Leukemia Explained With Pictures
Leukemia Explained With Pictures (webmd.com)
Colorectal Cancer Slideshow: Screening Tests, Stages, Symptoms, Treatments, and Risk Factors
Colorectal Cancer Slideshow: Screening Tests, Stages, Symptoms, Treatments, and Risk Factors (webmd.com)
Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer: cohort study |...
Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer: cohort study |... (bmj.com)
Airplane Crash - Safest Seat - How to Survive Plane Accident - NTSB Data - Flight Records
Airplane Crash - Safest Seat - How to Survive Plane Accident - NTSB Data - Flight Records (popularmechanics.com)
Ovarian cancer: Causes, symptoms, and treatments
Ovarian cancer: Causes, symptoms, and treatments (medicalnewstoday.com)
Understanding treatment and prognosis of male breast cancer
Understanding treatment and prognosis of male breast cancer (news-medical.net)
Cancer survival rates - NHS
Cancer survival rates - NHS (nhs.uk)
Settled Abroad - Daily Chart: Data Wise | The Economic Times
Settled Abroad - Daily Chart: Data Wise | The Economic Times (economictimes.indiatimes.com)