One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Antibacterial used topically in burn therapy.
Material, usually gauze or absorbent cotton, used to cover and protect wounds, to seal them from contact with air or bacteria. (From Dorland, 27th ed)
Inorganic compounds that contain silver as an integral part of the molecule.
Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Substances that are destructive to protozoans.
Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals.
One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.
A genus of protozoa parasitic to birds and mammals. T. gondii is one of the most common infectious pathogenic animal parasites of man.
Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)
Fluorocarbon polymers are synthetic, high-molecular-weight compounds consisting of carbon chains with fluorine atoms replacing hydrogen atoms, known for their chemical and thermal stability, as well as their resistance to water, oil, and heat, which make them useful in various medical applications such as biocompatible coatings, drug delivery systems, and implant materials.
Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.
A water-soluble medicinal preparation applied to the skin.
Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
Infection caused by the protozoan parasite TOXOPLASMA in which there is extensive connective tissue proliferation, the retina surrounding the lesions remains normal, and the ocular media remain clear. Chorioretinitis may be associated with all forms of toxoplasmosis, but is usually a late sequel of congenital toxoplasmosis. The severe ocular lesions in infants may lead to blindness.

Recombinant bactericidal/permeability-increasing protein (rBPI21) in combination with sulfadiazine is active against Toxoplasma gondii. (1/178)

The activity of recombinant bactericidal/permeability-increasing protein (rBPI21), alone or in combination with sulfadiazine, on the intracellular replication of Toxoplasma gondii was assessed in vitro and in mice with acute toxoplasmosis. rBPI21 markedly inhibited the intracellular growth of T. gondii in human foreskin fibroblasts (HFFs). Following 72 h of exposure, the 50% inhibitory concentration of rBPI21 for T. gondii was 2.6 micrograms/ml, whereas only slight cytotoxicity for HFF cells was observed at the concentrations tested. Subsequent mathematical analyses revealed that the combination of rBPI21 with sulfadiazine yielded slight to moderate synergistic effects against T. gondii in vitro. Infection of mice orally with C56 cysts or intraperitoneally (i.p.) with RH tachyzoites resulted in 100% mortality, whereas prolongation of the time to death or significant survival (P = 0.002) was noted for those animals treated with 5 to 20 mg of rBPI21 per kg of body weight per day. Treatment with rBPI21 in combination with sulfadiazine resulted in significant (P = 0.0001) survival of mice infected i.p. with tachyzoites but not of mice infected orally with T. gondii cysts. These results indicate that rBPI21 is active in vitro and in vivo against T. gondii and that its activity is significantly enhanced when it is used in combination with sulfadiazine. To our knowledge, this is the first report of the activity of rBPI21 against a protozoan parasite.  (+info)

Fetal cataract in congenital toxoplasmosis. (2/178)

We report a case of the prenatal diagnosis of fetal cataract due to congenital toxoplasmosis. To the best of our knowledge, this is the first report of such a case. We discuss the long-term ocular sequelae of the condition and how they should affect prenatal counselling.  (+info)

Early aqueous humor analysis in patients with human ocular toxoplasmosis. (3/178)

To evaluate the diagnostic sensitivity of a panel of laboratory tests for ocular toxoplasmosis performed at the time of presentation, paired samples of aqueous humor and serum were collected from 49 consecutive episodes of ocular toxoplasmosis with a clinical course of less than 3 weeks. Total immunoglobulin G (IgG) and Toxoplasma gondii-specific IgG, IgM, and IgA were quantified by enzyme-linked immunosorbent assay. The avidity of T. gondii-specific IgG was determined, and DNA extracted from aqueous humor was amplified for detection of a glycoprotein B gene sequence of T. gondii. The diagnosis was confirmed for 73% (36 of 49) of the patients; this rate rose to 79.5% if data from a later analysis of aqueous humor derived from five of the negative patients were included. The analysis of serum (detection of T. gondii-specific IgM and analysis of consecutive serum samples) alone did not contribute to the diagnosis. Calculation of local antibody production lacked diagnostic sensitivity when it was determined less than 3 weeks after the manifestation of clinical symptoms (28 of 49 patients [57%]), but this rose to 70% after an analysis of a second aqueous humor sample. The antibody avidity index attained diagnostic significance in only 8 of 43 instances (19%), and T. gondii DNA was amplified from no more than 6 of 39 (16%) aqueous humor samples. However, T. gondii-specific IgA was found within the aqueous humors of 11 of 43 patients (26%); measurement of the T. gondii-specific IgA level thus contributed substantially to the diagnostic sensitivity of the laboratory tests.  (+info)

Suppression of leukocyte chemotaxis in vitro by chemotherapeutic agents used in the management of thermal injuries. (4/178)

Polymorphonuclear leukocytes from burned patients exhibit suppressed chemotaxis possibly related to the susceptibility of such patients to opportunistic infection. This study assesses the effect of normal serum upon burn-suppressed leukocytes and the effects of three commonly used topical chemotherapeutic agents upon the chemotaxis exhibited by granulocytes from normal controls. In vitro incubation with normal serum restored chemotaxis to normal in the suppressed granulocytes from burned patients. The serum factor responsible for this restoration was heat labile. Serum albumin alone did not exhibit this effect. Both mafenide and silver sulfadiazine suppressed the chemotactic function of granulocytes obtained from normal controls, while silver nitrate exhibited no such activity. Studies of the chemotactic function of control granulocytes after incubation with sera from burned patients yielded similar results; only the sera from patients treated with silver nitrate failed to suppress normal leukotaxis. The chemotactic impairment found in leukocytes from burned patients, however, while related to burn size and predictive of prognosis, did not vary with the agent used for the topical therapy. These data suggest the presence of a reversible intrinsic defect in leukotaxis consequent to burn injury, related to some factor deficient in burn serum. In addition, extrinsic impairment of normal granulocyte leukotaxis by two commonly used chemotherapeutic agents is demonstrated.  (+info)

Treatment of gonorrhea in the male with trimethoprim-sulfamethoxazole using a one- or two-dose regimen. (5/178)

One hundred and eighty-four male patients with uncomplicated gonorrhea were treated in a randomized double-blind trial using two drug regimens. The combinations used were co-trimoxazole (trimethoprim, 80 mg and sulfamethoxazole, 400 mg) and TMP-SDZ (sulfadiazine, 400 mg and trimethoprim, 80 mg). In 43 patients who received eight tablets of co-trimoxazole in a single dose the cure rate was 88%. In the 46 patients who received a second dose of eight tablets 24 hours later the cure rate was 100%. When TMP-SDZ was used according to the same schedule the respective cure rates were 85% (41 patients) and 86% (35 patients). It is suggested that the two-dose regimen with co-trimoxazole is very effective in the treatment of uncomplicated urethral gonorrhea in the male and that the single-dose regimen, although less effective, may well prove adequate in patients defaulting after the initial treatment. At the present time, and with our local conditions, this form of treatment should be reserved for patients sensitive to penicillin or whose infections are resistant to this agent. The attack rate for patients having an episode of gonorrhea in the 12-month period immediately preceding the trial bore a direct relation to the outcome of therapy. It was highest (26%) in the group with an unsatisfactory outcome and lowest(4.3%) in the group with the highest cure rate. No adverse toxic reactions to the drug were recorded.  (+info)

Anti-toxoplasma activities of antiretroviral drugs and interactions with pyrimethamine and sulfadiazine in vitro. (6/178)

The anti-Toxoplasma activities of nine antiretroviral drugs were examined in vitro. Nucleoside analogs had no effect on parasite growth, whereas ritonavir and nelfinavir were inhibitory for Toxoplasma, with 50% inhibitory concentrations of 5.4 and 4.0 microg/ml, respectively. None of the antiviral drugs affected the anti-Toxoplasma activity of pyrimethamine or sulfadiazine.  (+info)

Inactivation of Treponema pallidum by silver sulfadiazine. (7/178)

Silver sulfadiazine, an anti-infectious agent for the prevention and treatment of burn sepsis, has been found to possess antitreponemal activity against Treponema pallidum. At 28 C, complete inactivation of the organism was produced by exposure of the organism to a concentration of 50 mug of the drug per ml for 1 to 5 min, 12 to 25 mug/ml for 10 to 15 min, and 6.2 mug/ml for 30 min. At 37 C, the amounts of silver sulfadiazine required for inactivation were two- to fourfold less.  (+info)

Granulomatous amebic encephalitis in a patient with AIDS: isolation of acanthamoeba sp. Group II from brain tissue and successful treatment with sulfadiazine and fluconazole. (8/178)

A patient with AIDS, treated with highly active antiretroviral therapy and trimethoprim-sulfamethoxazole, presented with confusion, a hemifield defect, and a mass lesion in the right occipital lobe. A brain biopsy confirmed granulomatous amebic encephalitis (GAE) due to Acanthamoeba castellanii. The patient was treated with fluconazole and sulfadiazine, and the lesion was surgically excised. This is the first case of AIDS-associated GAE responding favorably to therapy. The existence of a solitary brain lesion, absence of other sites of infection, and intense cellular response in spite of a very low CD4 count conditioned the favorable outcome. We review and discuss the diagnostic microbiologic options for the laboratory diagnosis of infections due to free-living amebae.  (+info)

Sulfadiazine is an antibacterial drug, specifically a sulfonamide. It is chemically described as 4-amino-N-(2-pyrimidinyl)benzenesulfonamide. Sulfadiazine works by inhibiting the bacterial synthesis of dihydrofolic acid, which is essential for bacterial growth and reproduction.

It is used to treat a wide range of infections caused by susceptible bacteria, including urinary tract infections, respiratory infections, and certain types of meningitis. Sulfadiazine is often combined with other antibiotics, such as trimethoprim, to increase its effectiveness against certain bacteria.

Like all sulfonamides, sulfadiazine can cause side effects, including skin rashes, allergic reactions, and stomach upset. It should be used with caution in people who are allergic to sulfa drugs or have kidney or liver disease. Additionally, it is important to note that the use of sulfonamides during pregnancy, especially during the third trimester, should be avoided due to the risk of kernicterus in the newborn.

Silver Sulfadiazine is a topical antimicrobial cream, primarily used for the prevention and treatment of burn wounds' infections. It has broad-spectrum activity against various bacteria, including gram-positive and gram-negative organisms, as well as some fungi. The cream creates a physical barrier that helps minimize bacterial growth and contains silver, which has antimicrobial properties. Silver Sulfadiazine is often used in combination with other burn wound care treatments to optimize healing and reduce the risk of complications such as sepsis.

The medical definition of Silver Sulfadiazine can be stated as:

A topical antimicrobial agent, chemically described as silver(I) 1-(4-amino-2-sulfonylphenyl)-2-(N-pyrimidin-2-ylsulfamoyl)ethanone dihydrate. It is primarily used for the prevention and treatment of infections associated with burn wounds due to its broad-spectrum antibacterial and antifungal properties. The compound is available as a white cream, which forms a protective layer on the wound, releasing silver ions that inhibit bacterial growth and promote healing.

Occlusive dressings are specialized bandages or coverings that form a barrier over the skin, preventing air and moisture from passing through. They are designed to create a moist environment that promotes healing by increasing local blood flow, reducing wound desiccation, and encouraging the growth of new tissue. Occlusive dressings can also help to minimize pain, scarring, and the risk of infection in wounds. These dressings are often used for dry, necrotic, or hard-to-heal wounds, such as pressure ulcers, diabetic foot ulcers, and burns. It is important to monitor the wound closely while using occlusive dressings, as they can sometimes lead to skin irritation or maceration if left in place for too long.

Silver compounds refer to chemical substances that combine silver (Ag) with one or more other elements. In the medical context, silver compounds are known for their antimicrobial properties and have been used in various medical applications such as wound dressings, creams, and coatings on medical devices.

Some examples of silver compounds include:

* Silver sulfadiazine (AgSD): a common topical antibiotic used to prevent and treat bacterial infections in burn wounds.
* Silver nitrate (AgNO3): a strong antiseptic used to treat wounds, skin infections, and eye conditions such as neonatal conjunctivitis.
* Silver chloride (AgCl): a compound used in some wound dressings for its antimicrobial properties.
* Silver proteinate: a silver compound that is often used in dietary supplements and claimed to have immune-boosting and anti-inflammatory effects, although its efficacy is not well established.

It's important to note that while silver compounds can be effective antimicrobial agents, they can also have potential side effects such as skin irritation, discoloration, and in some cases, argyria (a bluish-gray discoloration of the skin caused by excessive accumulation of silver). Therefore, they should be used under the guidance of a healthcare professional.

Anti-infective agents, local, are medications that are applied directly to a specific area of the body to prevent or treat infections caused by bacteria, fungi, viruses, or parasites. These agents include topical antibiotics, antifungals, antivirals, and anti-parasitic drugs. They work by killing or inhibiting the growth of the infectious organisms, thereby preventing their spread and reducing the risk of infection. Local anti-infective agents are often used to treat skin infections, eye infections, and other localized infections, and can be administered as creams, ointments, gels, solutions, or drops.

Antiprotozoal agents are a type of medication used to treat protozoal infections, which are infections caused by microscopic single-celled organisms called protozoa. These agents work by either killing the protozoa or inhibiting their growth and reproduction. They can be administered through various routes, including oral, topical, and intravenous, depending on the type of infection and the severity of the illness.

Examples of antiprotozoal agents include:

* Metronidazole, tinidazole, and nitazoxanide for treating infections caused by Giardia lamblia and Entamoeba histolytica.
* Atovaquone, clindamycin, and pyrimethamine-sulfadoxine for treating malaria caused by Plasmodium falciparum or other Plasmodium species.
* Pentamidine and suramin for treating African trypanosomiasis (sleeping sickness) caused by Trypanosoma brucei gambiense or T. b. rhodesiense.
* Nitroimidazoles, such as benznidazole and nifurtimox, for treating Chagas disease caused by Trypanosoma cruzi.
* Sodium stibogluconate and paromomycin for treating leishmaniasis caused by Leishmania species.

Antiprotozoal agents can have side effects, ranging from mild to severe, depending on the drug and the individual patient's response. It is essential to follow the prescribing physician's instructions carefully when taking these medications and report any adverse reactions promptly.

I'm sorry for any confusion, but "Silver" is not a medical term. It is a chemical element with the symbol Ag and atomic number 47. Silver is a soft, white, lustrous transition metal that occurs in its pure, free form (native silver) as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite.

In the medical field, silver compounds have been used for their antimicrobial properties. For example, silver sulfadiazine is a common topical cream used to prevent or treat wound infections. Colloidal silver, a suspension of silver particles in a liquid, has also been promoted as a dietary supplement and alternative treatment for various conditions, but its effectiveness and safety are not well-established.

Coccidiostats are a type of medication used to prevent and treat coccidiosis, which is an infection caused by protozoan parasites of the genus Coccidia. These medications work by inhibiting the growth and reproduction of the parasites in the gastrointestinal tract of animals, particularly poultry and livestock.

Coccidiostats are commonly added to animal feed to prevent infection and reduce the spread of coccidiosis within a flock or herd. They can also be used to treat active infections, often in combination with other medications. Common examples of coccidiostats include sulfaquinoxaline, monensin, and lasalocid.

It's important to note that the use of coccidiostats in food-producing animals is regulated by government agencies such as the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) to ensure their safe use and to minimize the risk of residues in animal products.

Pyrimethamine is an antiparasitic medication that is primarily used to treat and prevent protozoan infections, such as toxoplasmosis and malaria. It works by inhibiting the dihydrofolate reductase enzyme, which is essential for the parasite's survival. By doing so, it interferes with the synthesis of folate, a vital component for the growth and reproduction of the parasite.

Pyrimethamine is often used in combination with other medications, such as sulfonamides or sulfones, to increase its effectiveness and prevent the development of drug-resistant strains. Common side effects of pyrimethamine include nausea, vomiting, loss of appetite, and headache. It is important to note that pyrimethamine should only be used under the supervision of a healthcare professional due to its potential for serious side effects and interactions with other medications.

Atovaquone is an antiprotozoal medication used for the treatment and prevention of certain parasitic infections. It works by inhibiting the mitochondria of the parasites, disrupting their energy production and ultimately leading to their death. Atovaquone is available as a oral suspension or coated tablets and is often prescribed for conditions such as Pneumocystis pneumonia (PCP), Toxoplasma gondii encephalitis, and babesiosis. It is also used for the prevention of PCP in people with weakened immune systems due to HIV/AIDS or other causes.

The medical definition of Atovaquone can be stated as:

"Atovaquone is an antiprotozoal medication (synthetic hydroxynaphthoquinone) that exhibits activity against a variety of protozoa, including Plasmodium falciparum (the parasite responsible for malaria), Pneumocystis jirovecii (the causative agent of PCP), Toxoplasma gondii, and Babesia microti. It is used primarily for the treatment and prevention of PCP in individuals with compromised immune systems, as well as for the treatment of babesiosis and toxoplasmosis."

Burns are injuries to tissues caused by heat, electricity, chemicals, friction, or radiation. They are classified based on their severity:

1. First-degree burns (superficial burns) affect only the outer layer of skin (epidermis), causing redness, pain, and swelling.
2. Second-degree burns (partial-thickness burns) damage both the epidermis and the underlying layer of skin (dermis). They result in redness, pain, swelling, and blistering.
3. Third-degree burns (full-thickness burns) destroy the entire depth of the skin and can also damage underlying muscles, tendons, and bones. These burns appear white or blackened and charred, and they may be painless due to destroyed nerve endings.

Immediate medical attention is required for second-degree and third-degree burns, as well as for large area first-degree burns, to prevent infection, manage pain, and ensure proper healing. Treatment options include wound care, antibiotics, pain management, and possibly skin grafting or surgery in severe cases.

Toxoplasmosis is a zoonotic disease, meaning it can be transmitted from animals to humans. It is caused by the intracellular protozoan parasite Toxoplasma gondii. This parasite can infect a wide range of warm-blooded animals, including birds and mammals, as intermediate hosts. However, cats are the primary definitive host for this parasite because the sexual stage of the parasite's life cycle occurs in their intestines, leading to the shedding of oocysts (environmentally resistant stages) in their feces.

Animals can become infected with Toxoplasma gondii through several routes:

1. Ingestion of sporulated oocysts from contaminated soil, water, or food.
2. Consumption of tissue cysts present in the tissues of infected animals during predation.
3. Vertical transmission (transplacental) from an infected mother to her offspring.

Clinical signs and symptoms of toxoplasmosis in animals can vary depending on their age, immune status, and the parasite's virulence. In many cases, animals may not show any apparent signs of infection, but some may develop:

1. Generalized illness with fever, lethargy, and loss of appetite.
2. Lymphadenopathy (swollen lymph nodes).
3. Neurological symptoms such as tremors, ataxia (lack of coordination), or seizures if the central nervous system is affected.
4. Eye lesions, including inflammation and scarring of the retina, which can lead to vision loss in severe cases.
5. Reproductive issues, such as abortion, stillbirths, or birth defects in offspring when pregnant females are infected.

It is important to note that while toxoplasmosis can cause significant health problems in animals, particularly in immunocompromised individuals and developing fetuses, it is often asymptomatic or mild in healthy adult animals. Nonetheless, the zoonotic potential of Toxoplasma gondii highlights the importance of practicing good hygiene and taking necessary precautions when handling infected animals or their waste to minimize the risk of transmission to humans.

"Toxoplasma" is a genus of protozoan parasites, and the most well-known species is "Toxoplasma gondii." This particular species is capable of infecting virtually all warm-blooded animals, including humans. It's known for its complex life cycle that involves felines (cats) as the definitive host.

Infection in humans, called toxoplasmosis, often occurs through ingestion of contaminated food or water, or through contact with cat feces that contain T. gondii oocysts. While many people infected with Toxoplasma show no symptoms, it can cause serious health problems in immunocompromised individuals and developing fetuses if a woman becomes infected during pregnancy.

It's important to note that while I strive to provide accurate information, this definition should not be used for self-diagnosis or treatment. Always consult with a healthcare professional for medical advice.

Cerebral toxoplasmosis is a type of toxoplasmosis, which is an infection caused by the Toxoplasma gondii parasite. In cerebral toxoplasmosis, the infection primarily affects the brain, leading to inflammation and the formation of lesions or abscesses in the brain tissue.

This condition is most commonly observed in individuals with weakened immune systems, such as those living with HIV/AIDS, receiving immunosuppressive therapy after organ transplantation, or having other conditions that compromise their immune function. The infection can cause a range of neurological symptoms, including headaches, seizures, confusion, memory loss, poor coordination, and in severe cases, coma or even death. Early diagnosis and treatment with appropriate antiparasitic medications are crucial to manage the infection and prevent complications.

Fluorocarbon polymers are a type of synthetic polymeric material that contain carbon-fluorine bonds. These materials are known for their chemical inertness, high stability, and resistance to heat, chemicals, and water. They are often used in various medical applications such as in the coating of medical devices, implants, and drug delivery systems due to their biocompatibility and non-reactive properties.

Fluorocarbon polymers can be classified into two main categories: perfluoropolymers and fluoropolymers. Perfluoropolymers contain only carbon and fluorine atoms, while fluoropolymers contain other elements such as hydrogen, oxygen, or nitrogen in addition to carbon and fluorine.

Examples of fluorocarbon polymers used in medical applications include polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), and ethylene tetrafluoroethylene (ETFE). These materials have a wide range of properties that make them useful in various medical applications, such as low coefficient of friction, high electrical resistance, and excellent chemical resistance.

Chorioretinitis is a medical term that refers to the inflammation of the choroid and the retina, which are both important structures in the eye. The choroid is a layer of blood vessels that supplies oxygen and nutrients to the retina, while the retina is a light-sensitive tissue that converts light into electrical signals that are sent to the brain and interpreted as visual images.

Chorioretinitis can be caused by various infectious and non-infectious conditions, such as bacterial, viral, fungal, or parasitic infections, autoimmune diseases, or cancer. The symptoms of chorioretinitis may include decreased vision, floaters, blurry vision, sensitivity to light, and eye pain. Treatment for chorioretinitis depends on the underlying cause and may include antibiotics, antiviral medications, corticosteroids, or other immunosuppressive therapies. It is important to seek medical attention promptly if you experience any symptoms of chorioretinitis, as timely diagnosis and treatment can help prevent permanent vision loss.

A skin cream is not a medical term per se, but it generally refers to a topical emollient preparation intended for application to the skin. It contains a mixture of water, oil, and active ingredients, which are formulated to provide various benefits such as moisturizing, protecting, soothing, or treating specific skin conditions. The exact definition and composition may vary depending on the product's intended use and formulation.

Examples of active ingredients in skin creams include:

1. Moisturizers (e.g., glycerin, hyaluronic acid) - help to retain water in the skin, making it feel softer and smoother.
2. Emollients (e.g., shea butter, coconut oil, petrolatum) - provide a protective barrier that helps prevent moisture loss and soften the skin.
3. Humectants (e.g., urea, lactic acid, alpha-hydroxy acids) - attract water from the environment or deeper layers of the skin to hydrate the surface.
4. Anti-inflammatory agents (e.g., hydrocortisone, aloe vera) - help reduce redness, swelling, and itching associated with various skin conditions.
5. Antioxidants (e.g., vitamin C, vitamin E, green tea extract) - protect the skin from free radical damage and environmental stressors that can lead to premature aging.
6. Sunscreen agents (e.g., zinc oxide, titanium dioxide, chemical filters) - provide broad-spectrum protection against UVA and UVB rays.
7. Skin lighteners (e.g., hydroquinone, kojic acid, arbutin) - help reduce the appearance of hyperpigmentation and even out skin tone.
8. Acne treatments (e.g., benzoyl peroxide, salicylic acid, retinoids) - target acne-causing bacteria, unclog pores, and regulate cell turnover to prevent breakouts.

It is essential to choose a skin cream based on your specific skin type and concerns, as well as any medical conditions or allergies you may have. Always consult with a dermatologist or healthcare provider before starting a new skincare regimen.

Naphthoquinones are a type of organic compound that consists of a naphthalene ring (two benzene rings fused together) with two ketone functional groups (=O) at the 1 and 2 positions. They exist in several forms, including natural and synthetic compounds. Some well-known naphthoquinones include vitamin K1 (phylloquinone) and K2 (menaquinone), which are important for blood clotting and bone metabolism. Other naphthoquinones have been studied for their potential medicinal properties, including anticancer, antibacterial, and anti-inflammatory activities. However, some naphthoquinones can also be toxic or harmful to living organisms, so they must be used with caution.

An ointment is a semi-solid preparation, typically composed of a mixture of medicinal substance with a base, which is usually greasy or oily. The purpose of the base is to act as a vehicle for the active ingredient and allow it to be applied smoothly and evenly to the skin or mucous membranes.

Ointments are commonly used in dermatology to treat various skin conditions such as eczema, psoriasis, rashes, burns, and wounds. They can also be used to deliver medication for localized pain relief, muscle relaxation, and anti-inflammatory or antibiotic effects.

The base of an ointment may consist of various ingredients, including petrolatum, lanolin, mineral oil, beeswax, or a combination of these. The choice of the base depends on the desired properties such as consistency, spreadability, and stability, as well as the intended route of administration and the specific therapeutic goals.

Trimethoprim is an antibiotic medication that is primarily used to treat bacterial infections. It works by inhibiting the bacterial enzyme dihydrofolate reductase, which is necessary for the synthesis of DNA and protein. This leads to bacterial cell death. Trimethoprim is often combined with sulfamethoxazole (a sulfonamide antibiotic) to create a more effective antibacterial therapy known as co-trimoxazole or TMP-SMX.

Medical Definition:
Trimethoprim is a synthetic antibacterial drug that selectively inhibits bacterial dihydrofolate reductase, an enzyme required for the synthesis of tetrahydrofolate, a cofactor involved in the biosynthesis of thymidine and purines. By blocking this essential pathway, trimethoprim disrupts bacterial DNA and protein synthesis, leading to bacteriostatic activity against many gram-positive and gram-negative bacteria. Trimethoprim is often combined with sulfamethoxazole (a sulfonamide antibiotic) to create a more effective antibacterial therapy known as co-trimoxazole or TMP-SMX, which inhibits two consecutive steps in the bacterial folate synthesis pathway.

Sulfamethoxazole is a type of antibiotic known as a sulfonamide. It works by interfering with the ability of bacteria to produce folic acid, which is necessary for their growth and survival. Sulfamethoxazole is often combined with trimethoprim (another antibiotic) in a single medication called co-trimoxazole, which is used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections.

The medical definition of Sulfamethoxazole can be found in various pharmaceutical and medical resources, here are some examples:

* According to the Merck Manual, Sulfamethoxazole is a "synthetic antibacterial drug that inhibits bacterial synthesis of folic acid by competing with para-aminobenzoic acid for the enzyme dihydropteroate synthetase."
* According to the British National Formulary (BNF), Sulfamethoxazole is a "sulfonamide antibacterial agent, active against many Gram-positive and Gram-negative bacteria. It is often combined with trimethoprim in a 5:1 ratio as co-trimoxazole."
* According to the National Library of Medicine (NLM), Sulfamethoxazole is a "synthetic antibacterial agent that is used in combination with trimethoprim for the treatment of various bacterial infections. It works by inhibiting the bacterial synthesis of folic acid."

It's important to note that, as any other medication, Sulfamethoxazole should be taken under medical supervision and following the instructions of a healthcare professional, as it can cause side effects and interact with other medications.

Ocular toxoplasmosis is an inflammatory eye disease caused by the parasitic infection of Toxoplasma gondii in the eye's retina. It can lead to lesions and scarring in the retina, resulting in vision loss or impairment. The severity of ocular toxoplasmosis depends on the location and extent of the infection in the eye. In some cases, it may cause only mild symptoms, while in others, it can result in severe damage to the eye. Ocular toxoplasmosis is usually treated with medications that target the Toxoplasma gondii parasite, such as pyrimethamine and sulfadiazine, often combined with corticosteroids to reduce inflammation.

... is used in plant research for selecting and maintaining genetically manipulated cells. Sulfadiazine works by ... Silver sulfadiazine "Sulfadiazine". The American Society of Health-System Pharmacists. Archived from the original on 20 ... Sulfadiazine is available in multiple generic tablets of 500 mg. For urinary tract infections, the usual dose is 4 to 6 grams ... Sulfadiazine was approved for medical use in the United States in 1941. It is on the World Health Organization's List of ...
... was discovered in the 1960s. It is on the World Health Organization's List of Essential Medicines. It is ... When silver sulfadiazine is absorbed in significant amounts, it can increase effects and side effects of some drugs such as ... Sulfadiazine Singer AJ, Taira BR, Lee CC (2013). "Thermal Burns". In Marx J, Walls R, Hockberger R (eds.). Rosen's Emergency ... Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full ...
Schlossberg D, Samuel R (2011). "Sulfadiazine". Antibiotic Manual: A Guide to Commonly Used Antimicrobials (1st ed.). Shelton, ... sulfadiazine, and triamterene. Urolithiasis refers to stones originating anywhere in the urinary system, including the kidneys ...
Redirects to Silver sulfadiazine. SSKI stacofylline (INN) Stadol Stahist Stalevo 100 stallimycin (INN) stamulumab (INN, USAN) ...
... is available as a fixed-dose combination medication with silver sulfadiazine for the treatment of canine otitis ... "Baytril Otic- enrofloxacin, silver sulfadiazine emulsion". DailyMed. 27 March 2023. Retrieved 13 April 2023. Morgan D, Kaufman ...
Fuller FW (2009). "The side effects of silver sulfadiazine". J. Burn Care Res. 30 (3): 464-70. doi:10.1097/BCR.0b013e3181a28c9b ... anti-inflammatory for treatment of arthritis silver sulfadiazine - antibacterial zinc pyrithione - antibacterial and antifungal ...
"ReBalance® sulfadiazine/pyrimethamine oral suspension for horses". Prnpharmacal.com. Archived from the original on 2016-08-20. ... Currently, three FDA approved treatments are available in the US: ReBalance (sulfadiazine and pyrimethamine), Marquis ( ...
ISBN 978-0-387-68233-4. Stephan, Sittig (2014). Sorption, Transformation and Transport of Sulfadiazine in a loess and a sandy ... Microbacterium lacus has the ability to degrade sulfadiazine. Parte, A.C. "Microbacterium". LPSN. "Microbacterium lacus Taxon ... "Degradation of Sulfadiazine by Microbacterium lacus Strain SDZm4, Isolated from Lysimeters Previously Manured with Slurry from ... Sulfadiazine-Medicated Pigs". Applied and Environmental Microbiology. 79 (8): 2572-2577. doi:10.1128/AEM.03636-12. PMC 3623193 ...
Silver sulfadiazine (SSD) is a compound containing silver and the antibiotic sodium sulfadiazine, which was developed in 1968. ... Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. It ... silver sulfadiazine in treatment of partial-thickness burn wounds in children: a systematic review and meta-analysis". Wound ... Choi YJ, Lim JK, Park JJ, Huh H, Kim DJ, Gong CH, Yoon SZ (June 2017). "Chlorhexidine and silver sulfadiazine coating on ...
... is typically given with folinic acid and sulfadiazine. Sulfonamides (e.g. sulfadiazine) inhibit dihydropteroate ... In combination with a long-acting sulfonamide such as sulfadiazine, it was widely used, such as in Fansidar, though resistance ... Pyrimethamine is also used in combination with sulfadiazine to treat active toxoplasmosis. The two drugs bind the same ...
Some strains have enhanced resistance to sulfadiazine and tetracycline. Several strains of C. suis are known to have an ...
MoPn has been shown to be sensitive to sulfadiazine. In contrast to Chlamydia trachomatis, Chlamydia muridarum lacks a ...
Such drugs include: Sulfonamides, including sulfadiazine, sulfasalazine and trimethoprim/sulfamethoxazole. Sulfonylureas like ...
Silver sulfadiazine is used as an antiseptic ointment for extensive burns. An equilibrium dispersion of colloidal silver with ...
Other popular recommendations include triple dye, betadine, bacitracin, or silver sulfadiazine. With regards to the medicinal ...
Additionally, chitosan-based nanogels carrying an antibiotic, silver sulfadiazine, were found to decrease the size of second- ... "Alginate coated chitosan nanogel for the controlled topical delivery of Silver sulfadiazine". Carbohydrate Polymers. 177: 194- ...
Sulfadiazine Sulfamethazine Sulfamethizole Roblin RO, Williams JH, Winnek PS, English JP (1940). "Chemotherapy. II. Some ...
Sulfonamides (sulfadiazine or sulfamethoxazole) may be added for treatment of neurological symptoms. The disease is regarded as ...
He was treated with benzyl penicillin and sulphadiazine administered intravenously. A specimen of CSF was taken and sent for ...
Sulfadiazine (20 mg/kg orally) once or twice a day is a commonly used. Infected horses should also be placed on pyrimethamine ...
Wound dressings containing silver sulfadiazine or silver nanomaterials are used to treat external infections. Silver is also ...
... species have varying inclusion morphology, varying extrachromosomal plasmid content, and varying sulfadiazine ...
If the fetus has been infected, the pregnant woman can be treated with pyrimethamine and sulfadiazine, with folinic acid, after ... During pregnancy, spiramycin or pyrimethamine/sulfadiazine and folinic acid may be used for treatment. Up to half of the ... sulfadiazine, and folinic acid (USAN: leucovorin)), i.e., if the drugs produce no effect clinically and no improvement on ... an antimalarial medication Sulfadiazine - an antibiotic used in combination with pyrimethamine to treat toxoplasmosis ...
"Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin". Burns. 29 (8): 834-6. doi:10.1016/ ...
Silver sulfadiazine does not appear to differ from silver containing foam dressings with respect to healing. Burns can be very ... Silver sulfadiazine (a type of antibiotic) is not recommended as it potentially prolongs healing time. There is insufficient ... a subsequent review from 2012 did not find improved healing over silver sulfadiazine. There were only three randomized ...
After diagnosis, they were treated with flucytosine, pentamidine, fluconazole, sulfadiazine, a macrolide antibiotic and ...
... in combination with sulfadiazine is active against Toxoplasma gondii". Antimicrobial Agents and Chemotherapy. American Society ...
Bishop, Ann; McConnachie, Elspeth W. (1948). "Resistance to sulphadiazine and 'paludrine' in the malaria parasite of the fowl ( ... Bishop, Ann; McConnachie, Elspeth W. (1950). "Sulphadiazine-resistance in Plasmodium gallinaceum and its relation to other ...
Wassermann, D.; M. Schlotterer, F. Lebreton, J. Levy, M.C. Guelfi (1989). "Use of topically applied silver sulphadiazine plus ... It is a component in a burn treatment cream that also includes silver sulphadiazine. Concentrations used are 0.5 M for the ...
This was based on a lack of evident glycogen production and on resistance to the antibiotic sulfadiazine. In 1999 C. psittaci ...
Sulfadiazine is used in plant research for selecting and maintaining genetically manipulated cells. Sulfadiazine works by ... Silver sulfadiazine "Sulfadiazine". The American Society of Health-System Pharmacists. Archived from the original on 20 ... Sulfadiazine is available in multiple generic tablets of 500 mg. For urinary tract infections, the usual dose is 4 to 6 grams ... Sulfadiazine was approved for medical use in the United States in 1941. It is on the World Health Organizations List of ...
SILVER SULFADIAZINE cream. NDC Code(s): 49999-185-25, 49999-185-50 *Packager: Lake Erie Medical & Surgical Supply DBA Quality ... SILVER SULFADIAZINE cream. NDC Code(s): 52959-635-00, 52959-635-25, 52959-635-50, 52959-635-85 *Packager: H.J. Harkins Company ... SILVER SULFADIAZINE cream. NDC Code(s): 67877-124-05, 67877-124-10, 67877-124-20, 67877-124-25, view more 67877-124-40, 67877- ... SILVER SULFADIAZINE cream. NDC Code(s): 59762-0131-0, 59762-0131-2, 59762-0131-4, 59762-0131-5, view more 59762-0131-6, 59762- ...
Silver sulfadiazine cream, USP 1% is contraindicated in patients who are hypersensitive to silver sulfadiazine or any of the ... 4-Amino-N-2-pyrimidinylbenzenesulfonamidato-NN,01)-silver, sulfadiazine silver, silver (I) sulfadiazine, 4-amino-N-(2- ... Each gram of silver sulfadiazine cream contains 10mg of micronized silver sulfadiazine. ... Silver sulfadiazine is an antimicrobial agent that is FDA approved for the treatment of wound sepsis in patients with second ...
Silver Sulfadiazine Topical) - Drug Info, Side Effects, Research, Clinical Trials ... Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound [ ... sulfadiazine plus 6% epidermal growth factor (EGF) and 1% silver zinc sulfadiazine. The demographic data (age, sex, %body ... sulfadiazine plus EGF or silver zinc sulfadiazine. All parameter data were analyzed with repeated measure ANOVA and independent ...
Although chlorhexidine/silver sulfadiazine-impregnated catheters are useful in specific patient populations, they did not ... The purpose of this study was to determine if chlorhexidine/silver sulfadiazine-impregnated CVCs could decrease the CR-BSI rate ... Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood ... After introduction of chlorhexidine/silver sulfadiazine-impregnated catheters, 16 CR-BSIs occurred in 7,732 catheter days (2.1 ...
Silver sulfadiazine is eliminated via renal excretion. The sulfadiazine portion is eliminated quickly, whereas the silver ... Silver sulfadiazine (SSD) cream, most known for its use in the treatment of extensive burn wounds, is commonly used in the ... Silver sulfadiazine (SSD) cream, known for its antibacterial effects when used as a dressing for extensive burn wounds, is used ... Silver sulfadiazine therapy in widespread bullous disorders: Potential for toxicity. Emily M Mintz, Dornechia E George, Sylvia ...
Sulfadiazine is a sulfa antibiotic and trimethoprim is an antibiotic. This combination may be prescribed for susceptible ...
Home / Shop / Injectable / Norodine 24 / Sulfadiazine. Norodine 24 / Sulfadiazine. $25.00. Norodine 24 / Sulfadiazine quantity ... Be the first to review "Norodine 24 / Sulfadiazine" Cancel reply. Your email address will not be published. Required fields are ... Norodine 24 Sulfadiazine. A clear yellow aqueous solution for parenteral administration containing as active ingredients per ml ... Norodine 24 may be administered by intravenous injection when rapid blood levels of sulfadiazine and trimethoprim are required. ...
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DGIdb, The Drug Gene Interaction Database, is a research resource that can be used to search candidate genes or drugs against the known and potentially druggable genome.
Silver Nitrate and Silver Sulfadiazine are two different compounds with distinct properties and medical applications. Below are ... 1. Definition of Silver Nitrate and Silver Sulfadiazine * 2. Difference Between Silver Nitrate and Silver Sulfadiazine * 2.1. ... Silver Sulfadiazine: Silver Sulfadiazine is a topical antibacterial medication that is commonly used to prevent and treat ... Silver Sulfadiazine:. *Uses in medicine: Silver Sulfadiazine is primarily used to prevent and treat bacterial infections in ...
It is an aqueous solution comprising a synergistic combination of trimethoprim and sulfadiazine. For use of the Veterinarian. ... Sulfadiazine ....................... 200 mg Trimethoprim ................... ..... 40 mg Vehicle cbp 1 ml .................... ...
Send a request for the purchase of a pharmaceutical substance Sulfadiazine ...
CUADRO BÁSICO DE MEDICAMENTOS 2018. Ministerio de Salud Pública ...
C-PHARM. Gospodarska zona 15. HR-32000 Vukovar. OIB: 38466254572. +385 (0)32 534 154. +385 (0)32 534 154. [email protected]. ...
Sulfadiazine is an antibiotic from the group of sulfonamides.. In various investigations the near-surface groundwater was ... For your investigations and residue analysis, we can offer you the following metabolites of sulfadiazine:. [gview file="http:// ...
Sulfadiazine 200 mg. Trimethoprim 40 mg. Deskripsi. Formula khusus COLIBACT® Inj. merupakan kombinasi sulfadiazine dan ... Tag Archives: Kemoterapi Sulfadiazine dan trimotropine. COLIBACT® INJ. - Kemoterapeutika. August 14, 2012 Antibiotik, Produk ... SALURAN KEMIH fluoroquinolone growth promotor GUMBORO Kemoterapeutika Kemoterapi Kemoterapi injeksi Kemoterapi Sulfadiazine dan ...
Chlorhexidine-Silver Sulfadiazine-Impregnated Catheters. Catheters impregnated with chlorhexidine-silver sulfadiazine are ... in addition to chlorhexidine-silver sulfadiazine extraluminal impregnation. Use of chlorhexidine-silver sulfadiazine- ... Chlorhexidine-Silver Sulfadiazine-Impregnated Catheters Minocycline-Rifampin-Impregnated Catheters Catheter Hubs Containing ... Evaluation of chlorhexidine and silver-sulfadiazine impregnated central venous catheters for the prevention of bloodstream ...
quantité de Sulfadiazine argentique, 1%, crème, 100g, pot, unité. Ajouter au panier. Compare. Add to wishlist. UGS : DEXT_ ... Sulfadiazine argentique, 1%, crème, 100g, pot, unité remove. Calamine, 15%, lotion, 500 ml, flacon, unité remove. Nystatine, ... Sulfadiazine argentique, 1%, crème, 100g, pot, unité remove. Calamine, 15%, lotion, 500 ml, flacon, unité remove. Nystatine, ... Soyez le premier à laisser votre avis sur "Sulfadiazine argentique, 1%, crème, 100g, pot, unité" Annuler la réponse. Votre ...
... miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form which has the following structural ... Anti-Infective Silver Sulfadiazine SilvaDene Tube, EACH quantity. Add to cart. SKU: 1936665 Categories: Lotions, Ointments, ... 1% is a soft, white, water- miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form which has ...
This study evaluates the effect of prophylactic vitamin C administration on the efficiency of sulfadiazine-trimethoprim (SDT) ... This study evaluates the effect of prophylactic vitamin C administration on the efficiency of sulfadiazine-trimethoprim (SDT) ... arthritic SDT-treated (SDT group): The arthritic birds received SDT (Kimiaprim 48®, sulfadiazine 400 mg/ml + trimethoprim 80 mg ... Effect of Prophylactic Vitamin C Administration On The Efficiency of Florfenicol Or Sulfadiazine-Trimethoprim Antimicrobial ...
Producing high quality Synthetic Anti-Infective Drugs Sulfadiazine Sodium Powder CAS 547-32-0 products. ... High quality Synthetic Anti-Infective Drugs Sulfadiazine Sodium Powder CAS 547-32-0 from China, Chinas leading API ... Sulfadiazine sodium is a middle-effect sulfonamide antibacterial drug, which has antibacterial effect on many gram-positive and ...
Available products for generic Silver Sulfadiazine combination with manufacturers detail. Silver Sulfadiazine Eye Drops ... SILVER SULFADIAZINE EYE DROPS. Indications. Bacterial or viral conjunctivitis, bacterial or fungal corneal ulcer, blepharitis, ...
Sulfadiazine Sodium,Norfloxacin Nicotinic--Luoyang Zhengmu Bio-Tech Co.,Ltd. ...
Detailed drug Information for Urex. Includes common brand names, drug descriptions, warnings, side effects and dosing information.
Sulfadiazine. Children 27 kg: 0.5 g qd. Patients ,27 kg: 1 g qd ... for individuals allergic to penicillin and sulfadiazine). ...
During pregnancy, spiramycin and sulfadiazine can be used in the first trimester. Throughout the second trimester, spiramycin, ... Quadruple therapy refers to pyrimethamine, sulfadiazine, clindamycin, and prednisone (1 mg/kg of weight). Pyrimethamine should ... Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular ... Randomized trial of intravitreal clindamycin and dexamethasone versus pyrimethamine, sulfadiazine, and prednisolone in ...
... such as sulfadiazine and sulfamethoxine, at concentrations of 380 and 260 μg/L. Zhong also investigated and analyzed the ... such as the antibiotic sulfadiazine, the antihypertensive metoprolol, and the antiepileptic carbamazepine [46]. Moreover, these ...
sulfadiazine silver Sulfonamides are unsafe during pregnancy because they increase the likelihood of pregnancy loss. ...

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