A subclass of anhydrides with the general structure of dihydrofurandione. They can be substituted on any carbon atom. They modify and inhibit proteins and enzymes and are used in the acylation of amino- and hydroxyl groups.
Chemical compounds derived from acids by the elimination of a molecule of water.
Compounds used extensively as acetylation, oxidation and dehydrating agents and in the modification of proteins and enzymes.
Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.
Derivatives of SUCCINIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,4-carboxy terminated aliphatic structure.
Phthalic acid anhydrides. Can be substituted on any carbon atom. Used extensively in industry and as a reagent in the acylation of amino- and hydroxyl groups.

A quantitative comparison of induction and challenge concentrations inducing a 50% positive response in three skin sensitization tests; the guinea pig maximization test, adjuvant and patch test and Buehler test. (1/43)

The sensitivities of three skin sensitization tests such as the Guinea pig maximization test (GPMT), Adjuvant and patch test (APT) and Buehler test (BT), were quantitatively compared with reference to induction and challenge concentrations. Four chemical which had different physico-chemical properties (octanol-water partition coefficient (logP) and reactivity with NH2-group) were used in order to clarify the effect of the physico-chemical properties of chemicals on the sensitivity of the different methods. The induction concentrations inducing a 50% positive response (IC50) demonstrated extreme variation with the three methods. For example, the BT/GPMT ratio of IC50 values for 2,4-dinitrochlorobenzene was 33, whereas that for maleic anhydride was 300,000. The results were thought to be caused by difference properties such as the logP and reactivity of chemicals. This correlation was confirmed by using 2-dodecen-1-yl succinic anhydride, which had the same reactivity but higher logP than that of maleic anhydride. On the other hand, the challenge concentrations inducing 50% positive responses (CC50) were less affected by the methods and the BT/GPMT ratios for CC50 values were all within a 10-fold range. These results suggest that the sensitivity might be strongly different with reference to induction concentration, but not challenge concentration among the three methods.  (+info)

Treatment with succinic anhydride improves the immunogenicity of Shigella flexneri type 2a O-specific polysaccharide-protein conjugates in mice. (2/43)

Seroepidemiological data and a clinical trial with a Shigella sonnei O-specific polysaccharide (O-SP)-Pseudomonas aeruginosa recombinant exoprotein A (rEPA) conjugate provide evidence that a critical level of immunoglobulin G (IgG) lipopolysaccharide (LPS) antibodies in serum confers protection against shigellosis. We evaluated the immunogenicity of conjugates whose carrier proteins and O-SPs were treated with succinic anhydride (SA), which reacts with amino groups at neutral pH to form amide-linked carboxyls (succinylation). Conjugates were synthesized with either of two genetically inactivated medically useful toxins, the diphtheria protein CRM9 or rEPA, bound to the O-SP of Shigella flexneri type 2a. Conjugates composed of the succinylated protein, succinylated O-SP, or both succinylated components were administered to mice by a clinically relevant scheme, and their levels of serum IgG anti-LPS and anti-proteins were assayed 7 days after the second and third injections. CRM9 served as a more immunogenic carrier than rEPA. Conjugates composed of succinylated components were more immunogenic than the conjugates composed of the native components. SA treatment of both the carrier protein and the O-SP did not confer an advantage over the succinylated protein alone. Conjugates prepared with native proteins, in general, elicited slightly higher levels of IgG protein antibodies than conjugates composed of the SA-treated proteins.  (+info)

Clostridium difficile recombinant toxin A repeating units as a carrier protein for conjugate vaccines: studies of pneumococcal type 14, Escherichia coli K1, and Shigella flexneri type 2a polysaccharides in mice. (3/43)

Unlike the native protein, a nontoxic peptide (repeating unit of the native toxin designated rARU) from Clostridium difficile toxin A (CDTA) afforded an antigen that could be bound covalently to the surface polysaccharides of pneumococcus type 14, Shigella flexneri type 2a, and Escherichia coli K1. The yields of these polysaccharide-protein conjugates were significantly increased by prior treatment of rARU with succinic anhydride. Conjugates, prepared with rARU or succinylated (rARUsucc), were administered to mice by a clinically relevant dosage and immunization scheme. All conjugates elicited high levels of serum immunoglobulin G both to the polysaccharides and to CDTA. Conjugate-induced anti-CDTA had neutralizing activity in vitro and protected mice challenged with CDTA, similar to the rARU alone. Conjugates prepared with succinylated rARU, therefore, have potential for serving both as effective carrier proteins for polysaccharides and for preventing enteric disease caused by C. difficile.  (+info)

The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome. (4/43)

The 2.0 A resolution crystal structure of the ribosome inactivating protein saporin (isoform 6) from seeds of Saponaria officinalis is presented. The fold typical of other plant toxins is conserved, despite some differences in the loop regions. The loop between strands beta7 and beta8 in the C-terminal region which spans over the active site cleft appears shorter in saporin, suggesting an easier access to the substrate. Furthermore we investigated the molecular interaction between saporin and the yeast ribosome by differential chemical modifications. A contact surface inside the C-terminal region of saporin has been identified. Structural comparison between saporin and other ribosome inactivating proteins reveals that this region is conserved and represents a peculiar motif involved in ribosome recognition.  (+info)

A molecular logic gate. (5/43)

We propose a scheme for molecule-based information processing by combining well-studied spectroscopic techniques and recent results from chemical dynamics. Specifically it is discussed how optical transitions in single molecules can be used to rapidly perform classical (Boolean) logical operations. In the proposed way, a restricted number of states in a single molecule can act as a logical gate equivalent to at least two switches. It is argued that the four-level scheme can also be used to produce gain, because it allows an inversion, and not only a switching ability. The proposed scheme is quantum mechanical in that it takes advantage of the discrete nature of the energy levels but, we here discuss the temporal evolution, with the use of the populations only. On a longer time range we suggest that the same scheme could be extended to perform quantum logic, and a tentative suggestion, based on an available experiment, is discussed. We believe that the pumping can provide a partial proof of principle, although this and similar experiments were not interpreted thus far in our terms.  (+info)

Preparation of N-succinyl-chitosan and its physical-chemical properties as a novel excipient. (6/43)

The aim of this work is to prepare N-succinyl-chitosan (Suc-Chi) and measure physical-chemical properties for Suc-Chi as excipients. Suc-Chi were prepared via ring-opening reactions with succinic anhydride in Dimethyl Sulfoxide system. The physical-chemical properties of Suc-Chi, such as the degree of substitution (DS), solubility, isoelectric point (pI), glass transition temperature (Tg), partition coefficient (P(app)) and zata potential were detected respectively in order to evaluate their possibility as drug carriers. We obtained Suc-Chi DAC-90 (DS=0.33) and the data of physical-chemical properties for the product. The knowledges of physical-chemical properties for Suc-Chi are valuable for basic or applied purposes in biomedical and pharmaceutical sciences stabilization.  (+info)

Synthesis and paste properties of octenyl succinic anhydride modified early Indica rice starch. (7/43)

Octenyl succinic anhydride (OSA) modified early Indica rice starch was prepared in aqueous slurry systems using response surface methodology. The paste properties of the OSA starch were also investigated. Results indicated that the suitable parameters for the preparation of OSA starch from early Indica rice starch were as follows: reaction period 4 h, reaction temperature 33.4 degrees C, pH of reaction system 8.4, concentration of starch slurry 36.8% (in proportion to water, w/w), amount of OSA 3% (in proportion to starch, w/w). The degree of substitution was 0.0188 and the reaction efficiency was 81.0%. The results of paste properties showed that with increased OSA modification, the starch derivatives had higher paste clarity, decreased retrogradation and better freeze-thaw stability.  (+info)

Molecular location of a species-specific epitope on the hamster scrapie agent protein. (8/43)

Scrapie is a transmissible neurodegenerative disease of sheep and goats. An abnormal host protein, Sp33-37, is the major protein component of the scrapie agent and the only known disease- or agent-specific macromolecule. Two monoclonal antibodies (MAbs), 4H8 (immunoglobulin G2b [IgG2b]) and 6B11 (IgG1), produced by immunizing mice with the intact hamster 263K scrapie agent protein, Sp33-37Ha, were found to have species specificity similar to that reported previously for MAb 3F4 (IgG2a), which was produced by using PrP-27-30 as the immunogen (R. J. Kascsak, R. Rubenstein, P. A. Merz, M. Tonna-DeMasi, R. Fersko, R. I. Carp, H. M. Wisniewski, and H. Diringer, J. Virol. 61:3688-3693, 1987). These antibodies all bound to Sp33-37 derived from hamster but not from mouse cells. Competitive binding assays demonstrated that all three MAbs bound to the same or overlapping sites on Sp33-37Ha. The molecular location of the epitope for these antibodies was determined to within 10 residues by using an antigen competition enzyme-linked immunosorbent assay in which synthetic peptides spanning Sp33-37Ha residues 79 to 93 or 84 to 93 specifically inhibited binding of these antibodies to plates coated with purified Sp33-37Ha. A synthetic peptide with the mouse-specific sequence (83 to 92) that differed from the hamster sequence by substitution at two positions (MetHa-87----LeuMo-86 and MetHa-90----ValMo-89) did not inhibit antibody binding to Sp33-37Ha. MAb 3F4 binding to hamster Sp33-37 was eliminated by chemical modification of Sp33-37Ha with diethylpyrocarbonate or succinic anhydride and by cleavage with CNBr or trypsin. The effect of diethylpyrocarbonate on MAb 3F4 binding was not reversed by hydroxylamine treatment. MAb 3F4 binding was not affected by prolonged exposure of Sp33-37Ha to 70% formic acid or by boiling in sodium dodecyl sulfate. We conclude that the epitope for these MAbs is a linear determinant that includes Met-87, Lys-88, and Met-90 and that Met-90 is probably the major species-specific determinant.  (+info)

I'm sorry for any confusion, but "Succinic Anhydrides" is not a recognized medical term. Succinic anhydride is a chemical compound with the formula (CH2)2(CO)2O. It is used in organic synthesis as a dehydrating agent and acylating agent. If you're asking about a medical application or effect of succinic anhydride or its derivatives, I would need more specific information to provide an accurate and helpful response.

Anhydrides are chemical compounds that form when a single molecule of water is removed from an acid, resulting in the formation of a new compound. The term "anhydride" comes from the Greek words "an," meaning without, and "hydor," meaning water.

In organic chemistry, anhydrides are commonly formed by the removal of water from a carboxylic acid. For example, when acetic acid (CH3COOH) loses a molecule of water, it forms acetic anhydride (CH3CO)2O. Acetic anhydride is a reactive compound that can be used to introduce an acetyl group (-COCH3) into other organic compounds.

Inorganic anhydrides are also important in chemistry and include compounds such as sulfur trioxide (SO3), which is an anhydride of sulfuric acid (H2SO4). Sulfur trioxide can react with water to form sulfuric acid, making it a key intermediate in the production of this important industrial chemical.

It's worth noting that some anhydrides can be hazardous and may require special handling and safety precautions.

Acetic anhydride is a chemical compound with the formula (CH3CO)2O. It is a colorless liquid that is used as a reagent in organic synthesis, particularly in the production of cellulose acetate and other acetate esters. Acetic anhydride is also an important intermediate in the synthesis of certain pharmaceuticals and dyes.

In medical terminology, acetic anhydride is not typically used as a diagnostic or therapeutic agent. However, it can be used in laboratory settings to synthesize compounds that may have medical applications. For example, acetic anhydride has been used to produce certain antiviral drugs and antibiotics.

It is important to note that acetic anhydride can be harmful or fatal if swallowed, inhaled, or absorbed through the skin. It can cause burns and eye damage, and may be harmful to the respiratory system if inhaled. Therefore, it should be handled with care and used only in well-ventilated areas with appropriate personal protective equipment.

I believe there may be some confusion in your question. Maleic anhydride is not a medical term, but rather a chemical compound with the formula C2H2O3. It is a white crystalline solid that is used in industrial applications such as the production of polymers and resins.

If you are asking about a medical condition related to exposure or sensitivity to maleic anhydride, I would recommend consulting a medical professional for accurate information. However, in general, inhalation or skin contact with maleic anhydride can cause irritation and respiratory symptoms, and prolonged exposure may lead to more serious health effects. People with sensitivities or allergies to the compound may experience more severe reactions.

Succinates, in a medical context, most commonly refer to the salts or esters of succinic acid. Succinic acid is a dicarboxylic acid that is involved in the Krebs cycle, which is a key metabolic pathway in cells that generates energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.

Succinates can also be used as a buffer in medical solutions and as a pharmaceutical intermediate in the synthesis of various drugs. In some cases, succinate may be used as a nutritional supplement or as a component of parenteral nutrition formulations to provide energy and help maintain acid-base balance in patients who are unable to eat normally.

It's worth noting that there is also a condition called "succinic semialdehyde dehydrogenase deficiency" which is a genetic disorder that affects the metabolism of the amino acid gamma-aminobutyric acid (GABA). This condition can lead to an accumulation of succinic semialdehyde and other metabolic byproducts, which can cause neurological symptoms such as developmental delay, hypotonia, and seizures.

I'm sorry for any confusion, but "Phthalic Anhydrides" is not a medical term. It is a chemical compound with the formula C6H4(CO)2O. Phthalic anhydride is a white crystalline powder used in the industrial synthesis of plasticizers, resins, and dyes.

If you have any questions about medical terminology or concepts, please don't hesitate to ask!

Industrially, succinic anhydride is prepared by catalytic hydrogenation of maleic anhydride. Succinic anhydride hydrolyzes ... Succinic anhydride, is an organic compound with the molecular formula (CH2CO)2O. This colorless solid is the acid anhydride of ... 2, p. 560 Carlo Fumagalli (2006). "Succinic Acid and Succinic Anhydride". Kirk-Othmer Encyclopedia of Chemical Technology. New ... Chemical data Louis F. Fieser, E. L. Martin, R. L. Shriner, and H. C. Struck (1932). "Succinic Anhydride". Organic Syntheses. ...
Alkenyl succinic anhydrides (ASA) are derivatives of succinic anhydrides. One H of the succinic anhydride ring is replaced with ... "Process for reacting an olefin with maleic anhydride to obtain an alkenyl succinic anhydride", published 1968-11-19, assigned ... and less dark colored alkenyl succinic anhydride (ASA) were needed. The use of alkenylsuccinic anhydrides to hydrophobize ... Therefore, alkenyl succinic anhydrides can be converted into an emulsion only before the use in the paper machine, while AKD ...
Dehydration of succinic acid gives succinic anhydride. Succinate can be used to derive 1,4-butanediol, maleic anhydride, ... GABA is then metabolized by GABA transaminase to succinic semialdehyde. Finally, succinic semialdehyde is oxidized by succinic ... Succinic acid is a white, odorless solid with a highly acidic taste. In an aqueous solution, succinic acid readily ionizes to ... Fieser, Louis F.; Martin, E. L. (1932). "Succinic Anhydride". Organic Syntheses. 12: 66. doi:10.15227/orgsyn.012.0066. "Top ...
Castagnoli, Neal; Cushman, Mark (November 1971). "Condensation of succinic anhydrides with Schiff bases. Scope and mechanism". ... Castagnoli, Neal (1969-10-01). "Condensation of succinic anhydride with N-benzylidene-N-methylamine. Stereoselective synthesis ... he reported and studied in detail the condensation of cyclic anhydrides with imines (work that was based on a previous report ...
doi:10.1002/14356007.o18_o11 Gess, Jerome; Rend, Dominic (2005). "Alkenyl Succinic Anhydride (ASA)". TAPPI Journal. 4: 25-30. ... Related to AKDs, is alkenylsuccinic anhydride (ASA). As for AKDs, ASA reacts with hydroxy groups of the cellulose to form an ... ASA is prepared by the ene reaction of unsaturated hydrocarbons with maleic anhydride. As early as 1901, Edgar Wedekind ... In addition to the significantly more reactive alkenylsuccinic anhydrides (which do also hydrolyze rapidly in the presence of ...
... methyl succinic anhydride. The commercialization of the polyhydroxybutyric acid (PHB) or of homo- and copolymeric ... "Catalytic carbonylation of β-lactones to succinic anhydrides". J. Am. Chem. Soc. 126 (22). pp. 6842-6843. doi:10.1021/ja048946m ...
Succinic acid is notable as a component in the citric acid cycle. It forms a cyclic acid anhydride, succinic anhydride. ... Succinic acid and its esters are the parent members of this family of 1,4-dicarbonyls. ...
So succinic acid will yield succinic anhydride. For acids with carboxylic groups at position 1 and 6 this dehydration causes ... and anhydrides. In the case of anhydrides or amides, two of the carboxyl groups can come together to form a cyclic compound, ... or dehydrating it with acetic anhydride will yield a cyclic acid anhydride if the carbon atoms bearing acid groups are in ... A total of 26 minor acids (from 2 in pecan to 8% in peanut) were determined: 8 species derived from succinic acid, likely in ...
He, Guo-Qing; Song, Xiao-Yan; Ruan, Hui; Chen, Feng (2006). "Octenyl Succinic Anhydride Modified Early Indica Rice Starches ... He, Jinhua; Liu, Jie; Zhang, Genyi (2008). "Slowly Digestible Waxy Maize Starch Prepared by Octenyl Succinic Anhydride ... Octenyl succinic acid modified gum arabic "Compound Summary for CID 11276246 - Octenylsuccinic Acid". PubChem. ...
It can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride. NHS is commonly found in ...
1,4-Butanediol Succinic anhydride Merck Index, 12th edition, 1632. Lide, David R., ed. (2009-06-03). CRC Handbook of Chemistry ...
Fulgenolide is a lactone analog: one of the two succinic anhydride carbonyl groups is replaced by an alkyl link. Fulgenolides ... In organic chemistry, a fulgide is any of a class of photochromic compounds consisting of a bismethylene-succinic anhydride ... Fulgimide is an analog that has succinimide instead of succinic anhydride. It has nearl the same photochromic properties, but ... Various other carbonyl structures have been studied, in addition to the original succinic anhydride. The goals includ ...
Either the dye or the sugar is reacted with succinic anhydride. This forms an amide group with the sugar or an ester group with ... Either the dye or the sugar group can be succinylated by reacting a free alcohol group with succinic anhydride. The resulting ...
Oxidation of that product with chromium trioxide then leads to the substituted succinic anhydride (4). Treatment of anhydride ...
... is the precursor to the drug furobufen by Friedel-Crafts reaction with succinic anhydride. Dibenzofuran is a ...
... can be synthesized by acylation of biphenyl with succinic anhydride under Friedel-Crafts conditions. Moore RA, Derry S ...
"The Action of Diazomethane on Benzoic and Succinic Anhydrides, and a Reply to Malkin and Nierenstein". J. Am. Chem. Soc. 52 (4 ... Acid anhydrides can be used in place of acid chloride. The reaction yields a 1:1 mixture of the homologated acid and the ... "Trimethylsilyldiazomethane in the Preparation of Diazoketones via Mixed Anhydride and Coupling Reagent Methods: A New Approach ...
The reaction may be achieved by heating glyoxime to 150 °C in the presence of succinic anhydride; furazan will evaporate at ...
... is made from dihydroartemisinin (DHA) by reacting it with succinic acid anhydride in a basic medium. It is one of ...
Succinic anhydride N-Hydroxysuccinimide N-Bromosuccinimide International Union of Pure and Applied Chemistry (2014). ...
At several places AKD (alkyl ketene dimer) and ASA (alkenyl succinic anhydride) are used. Latest development is to use surface ... Common binders are styrene maleic anhydride copolymer or styrene-acrylate copolymer. The surface chemical composition is ...
It is manufactured from fluoranthene and succinic anhydride in the presence of aluminum chloride in a nitrobenzene solution. ( ...
Cationic starch and hydrophilic agents are also applied, including alkenyl succinic anhydride (ASA) and alkyl ketene dimers ( ... Co-styrene-maleic anhydride and co-styrene acrylate are common binders associated with a cationic starch pigment in Inkjet ... Common binders are styrene maleic anhydride copolymer or styrene-acrylate copolymer. The surface chemical composition is ...
Acids include isophthalic, terephthalic, adipic, benzoic, succinic acids and phthalic, maleic and trimellitic anhydride. ... Phthalic and trimellitic anhydrides may also be used. Polyols tend to be neopentyl glycol, 1,6-hexanediol and ... To make them waterborne organic acids or anhydrides are added in a two-stage process but there are other methods too. ... With alkyds typical methods include maleinazation of unsaturated fatty acids with maleic anhydride. This involves making a ...
In 2010, hydrophobically modified ε-polylysine was synthesized by reacting EPL with octenyl succinic anhydride (OSA). It was ...
Succinylation of the delignified wood substrate using succinic anhydride results in a nanostructured and mechanically strong ...
... from benzene and succinic anhydride. The intramolecular cyclization of 4-phenylbutanoic acid to 1-tetralone is catalyzed by ... The oxime of 1-tetralone reacts with acetic anhydride leading to aromatization of the cycloalkanone ring. The resulting N-(1- ... The tertiary alcohol formed in the Grignard reaction of 1-tetralone with phenylmagnesium bromide reacts with acetic anhydride ...
... either by ring-opening polymerization of succinic anhydride with ethylene oxide or by polycondensation of succinic acid and ...
Rxn of that product with succinic anhydride converts the pendant amine to a succinimide, affording the anxiolytic agent ...
In this reaction, benzene is reacted with succinic anhydride, the intermediate product is reduced and a second FC acylation ... In a related reaction, phenanthrene is synthesized from naphthalene and succinic anhydride in a series of steps which begin ... Acid anhydrides as well as carboxylic acids are also viable. A typical Lewis acid catalyst is aluminium trichloride. Because, ... Examples are the synthesis of thymolphthalein (a pH indicator) from two equivalents of thymol and phthalic anhydride: A ...
Industrially, succinic anhydride is prepared by catalytic hydrogenation of maleic anhydride. Succinic anhydride hydrolyzes ... Succinic anhydride, is an organic compound with the molecular formula (CH2CO)2O. This colorless solid is the acid anhydride of ... 2, p. 560 Carlo Fumagalli (2006). "Succinic Acid and Succinic Anhydride". Kirk-Othmer Encyclopedia of Chemical Technology. New ... Chemical data Louis F. Fieser, E. L. Martin, R. L. Shriner, and H. C. Struck (1932). "Succinic Anhydride". Organic Syntheses. ...
Anhydrides Survey of Succinic Anhydride in China. July 2010 , 6 pages , ID: SDE2CAEDB2FEN Guangzhou CCM Information Science & ...
Silanes & Silicones for Epoxy Resins Silanes and silicones can modify epoxy resin performance by improving adhesion and controlled release, modifying rheological behavior, altering optical/dielectric/low temperature properties, and providing thermal stress relaxation. Included are silane coupling agents, epoxy-functional silicones, silane and silicone hardeners, and organosilane-modified silica. ...
... succinic anhydride hydrolyses rapidly to succinic acid (DT50 = approx. 5 min), succinic anhydride is not expected to inhibit ... of succinic anhydride to aquatic microorganisms is assessed via read-across from its hydrolytic transformation product succinic ... This information is used in a read-across approach to assess the target substance succinic anhydride. For details and ... microbial respiration in STPs at concentrations of , 300 mg/L, corresponding to 254 mg/L succinic anhydride. ...
Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. Polymers https ... In order to ward off these infections, this paper explores the immobilization of triethoxysilylpropyl succinic anhydride ( ... Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. Polymers. ... Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. Polymers 2020 ...
The reactivities of maleic and succinic anhydrides were compared. Succinic anhydride/starch gave DS of 0.3 as compared to only ... The effects of varying reaction time, microwave power, anhydride and pyridine amount on the reaction yield and composition were ... For a given amount maleic anhydride higher amount pyridine gave higher DS. ... to prepare starch maleates with DS up to 0.25 was developed when starch in DMSO reacted with 0.5 equivalent maleic anhydride in ...
MODIFIED CORN STARCH (1-OCTENYL SUCCINIC ANHYDRIDE) (UNII: 461P5CJN6T) SUCROSE (UNII: C151H8M554) ...
modified corn starch (1-octenyl succinic anhydride) (UNII: 461P5CJN6T) polysorbate 80 (UNII: 6OZP39ZG8H) ...
POLYMERS WITH MALEIC ANHYDRIDE, MIXED DECYL OCTYL ESTERS, REACTION PRODUCTS WITH N,N-DIMETHYL-1,3-PROPANEDIAMINE, BENZYL ... Alkenyl Succinic Anhydrides (10 suppliers). ALKENYL(C16-C18) DIMETHYL AMINE ACETATE (2 suppliers). IUPAC Name: acetic acid;(Z)- ... ALKENYL(C18-C24)SUCCINIC ANHYDRIDE TRIS(HYDROXYMETHYL)AMINOMETHYL SUCCINIMIDE (1 supplier). 68516-11-0. ... ALKENES, C24-28 .ALPHA.-, POLYMERS WITH MALEIC ANHYDRIDE, C20-28-ALKYL ESTERS (1 supplier). 68188-50-1. ...
The epoxy curing agent dodecyl-succinic-anhydride, used in the epoxy molding area is also considered to be present at levels ... environmental exposure in the past to trichloroethylene and dodecyl-succinic-anhydride may have been at toxic concentrations. ...
Alkyl Succinic Anhydrides Market Research Report 2023 Market Promising Regions f … The global Alkyl Succinic Anhydrides Market ... team of analysts has employed the latest research tools and techniques to estimate the size of the Alkyl Succinic Anhydrides ...
Yan, Y.M.; Pilcher, G., Enthalpies of combustion of succinic anhydride, glutaric anhydride, and glutarimide, J. Chem. Thermodyn ... Yang, M.Y.; Pilcher, G., Enthalpies of combustion of succinic anhydride, glutaric anhydride, and glutarimide, J. Chem. ... Meng-Yan, Yang; Pilcher, G., Enthalpies of combustion of succinic anhydride, glutaric anhydride, and glutarimide, The Journal ... and the heat of combustion of succinic acid, Phil. Trans. Roy. Soc. London, 1955, 248, 23-44. [all data] ...
Structure and Properties of Octenyl Succinic Anhydride-Modified High-Amylose Japonica Rice Starches by Wei Zhang ... In this research, a high-amylose Japonica rice starch (amylose content 33.3%) was esterified with octenyl succinic anhydride ( ... In this research, a high-amylose Japonica rice starch (amylose content 33.3%) was esterified with octenyl succinic anhydride ( ... In this research, methacrylated Kefiran was synthesized by reacting Kefiran with methacrylic anhydride [...] Read more. ...
Scheme 4: Mechanochemical regiodirected FCR of anthracene dimer and succinic anhydride. Jump to Scheme 4 ... Figure 1: In situ Raman monitoring of reaction of phthalic anhydride with p-xylene. ...
... with the use of succinic anhydride (Cat-1) as a catalyst; some quinoline N-oxide was formed, and the selectivity was only 44% ( ... Polymaleic anhydride was not prepared and tested in this work because it decomposes at approximately 100 °C. These polymers ... Entry 2). The conversion of 1,2,3,4-tetrahydroquinoline was ,99% if maleic anhydride (Cat-2) was employed (Entry 3). However, ...
Simultaneously, four succinamic acids were prepared by the reaction of succinic anhydride with different amines. Posteriorly, ...
Slides were blocked using succinic anhydride under standard conditions (http://cmgm.stanford.edu/pbrown/). The arrays contained ...
The Application of Cellulose Nanocrystals Modified with Succinic Anhydride under the Microwave Irradiation for Preparation of ...
Suitable anhydrides include succinic, maleic, phthalic, trimellitic and hexahydrophthalic anhydrides.. More preferred (co) ... ScA denotes succinic anhydride; FA denotes fumaric acid and AdA denotes adipic acid. ... One example of a polar TPP is a maleic anhydride modified polypropylene. The method of attachment of the yarn tufts described ... A generic (co)polyester-amide may be formed by the condensation reaction of for example molecules having acid or anhydride ...
The Global Maleic Anhydride Market is the increase in the demand for lubricating oil additives across several regions. ... Alkenyl Succinic Anhydrides, Malic Acid, Fumaric Acid, Agricultural Chemicals, Others)Others and Regional Forecast, 2023-2030. ... Maleic Anhydride Market Size, Share & Industry Analysis, By Raw Material (N-Butane, Benzene), By Application (Unsaturated ...
... succinic acid and anhydride). PBS is also produced through trans-esterification at different temperatures and using different ... Polybutylene succinate producers also face problems such as delays in the receipt of raw materials such as succinic acid and 1 ... Polybutylene succinate raw materials, namely succinic acid and 1, 4 butanediols, are produced from petroleum feedstock. So, the ...
... maleic anhydride-alt-1-octadecene) (PMAO). PMAO contains succinic anhydride units that are reactive towards the oleylamine ... Transforming colloidal Cs4PbBr6 nanocrystals with poly(maleic anhydride-alt-1-octadecene) into stable CsPbBr3 perovskite ... Transforming colloidal Cs4PbBr6 nanocrystals with poly(maleic anhydride-alt-1-octadecene) into stable CsPbBr3 perovskite ...
"Nickel and nickel-platinum as active and selective catalyst for the maleic anhydride hydrogenation to succinic anhydride," ...
Gum acacia modified with n-octenyl succinic anhydride (OSA) is safe for use as an emulsifier in flavourings and in foods, finds ...
Market summary of Succinic anhydride Latest publish:2013/07/22 Keyword: * Market Data ...
Polyisobutylene Succinic Anhydrides (PIBSA) are available with active contents ranging from 60 to 100%. They can be diluted in ... PIBSA 1070(P/N) and 1100 are polyisobutylene succinic anhydrides manufactured via thermal process from a 1000 molecular weight ...
Succinic anhydride is not classified as highly flammable (i.e. a non flammable solid). Succinic anhydride is not classified ... The substance succinic anhydride is non flammable, not flammable in contact with water and is not pyrophoric.. Executive ... The substance succinic anhydride is non flammable, not flammable in contact with water and is not pyrophoric.. ...
Succinic acid is produced commercially by chemical processes from maleic anhydride, a petroleum-based raw material. Although ... Succinic acid (SA):. Succinic acid (SA) is another important cellulose derived platform chemical. It is member of the C4- ... Succinic acid anhydride produced via dehydrogenative cyclization reaction is utilized as a starting material to produce fumaric ... A more viable method is to use microorganisms to generate succinic acid. Furthermore, bio-based succinic acid has additional ...
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  • This information is used in a read-across approach to assess the target substance succinic anhydride. (europa.eu)
  • The substance succinic anhydride is non flammable, not flammable in contact with water and is not pyrophoric. (europa.eu)
  • A GLP study was conducted to determine the flammability (EC method A.10), the flammability in contact with water (EC method A.12) and the pyrophoric properties (EC method A.13) of the substance succinic anhydride and reported in 2010. (europa.eu)
  • This colorless solid is the acid anhydride of succinic acid. (wikipedia.org)
  • Maleic anhydride undergoes a similar reaction with polyisobutylene to give polyisobutylenylsuccinic anhydride, a common building block chemical in the petroleum additives industry. (wikipedia.org)
  • PIBSA 1070(P/N) and 1100 are polyisobutylene succinic anhydrides manufactured via thermal process from a 1000 molecular weight polyisobutylene. (kimestech.com)
  • PMAO contains succinic anhydride units that are reactive towards the oleylamine species present on the Cs 4 PbBr 6 nanocrystals' surface and produces polysuccinamic acid, which, in turn, triggers the Cs 4 PbBr 6 to CsPbBr 3 conversion. (rsc.org)
  • Maleic anhydride is a highly reactive chemical intermediate with a flash point of 218°F and is widely applied in the field of industrial chemistry. (thetechlane.com)
  • Based on medical interviews with workers, environmental exposure in the past to trichloroethylene and dodecyl-succinic-anhydride may have been at toxic concentrations. (cdc.gov)
  • Maleic anhydride undergoes the Alder-ene reaction with alkenes to give alkenylsuccinic anhydrides. (wikipedia.org)
  • The rising demand for maleic anhydride for the production of unsaturated polyester resin, which has a high demand in the building and construction industry is further bolstering the market in the forecast period. (thetechlane.com)
  • Succinic anhydride hydrolyzes readily to give succinic acid: (CH2CO)2O + H2O → (CH2CO2H)2 With alcohols (ROH), a similar reaction occurs, delivering the monoester: (CH2CO)2O + ROH → RO2CCH2CH2CO2H Succinic anhydride is used in acylations under Friedel-Crafts conditions, as illustrated by the industrial route to the drug Fenbufen. (wikipedia.org)
  • The effects of varying reaction time, microwave power, anhydride and pyridine amount on the reaction yield and composition were studied. (usda.gov)
  • Simultaneously, four succinamic acids were prepared by the reaction of succinic anhydride with different amines. (usp.br)
  • Maleic anhydride is a crucial ingredient in the production of fumaric acid. (thetechlane.com)
  • After gas chromatography and mass spectrometry (GC-MS) and pyrolysis gas chromatography and mass spectrometry (Py-GC-MS) analysis, it indicates that the possible volatiles and pyrolysis products in FAS are fumaric acid, maleic acid, maleic anhydride, phthalic acid, etc. (bvsalud.org)
  • Reactions of the 3α-hydroxy compounds IVa , Va and VIa with succinic anhydride resulted in the hemisuccinates IVi - VIi . (cas.cz)
  • Succinic anhydride, is an organic compound with the molecular formula (CH2CO)2O. (wikipedia.org)
  • The new report by Expert Market Research titled, 'Global Maleic Anhydride Market Share , Report and Forecast 2023-2028', gives an in-depth analysis of the global maleic anhydride market, assessing the market based on its segments like product types, end user industries, and major regions. (thetechlane.com)
  • Succinic anhydride is not classified as 'highly flammable' (i.e. a non flammable solid). (europa.eu)
  • Antibacterial Properties of Triethoxysilylpropyl Succinic Anhydride Silane (TESPSA) on Titanium Dental Implants. (upc.edu)
  • Succinic anhydride is not classified as being flammable to contact with water and is regarded as not being pyrophoric. (europa.eu)
  • The potential toxicity of succinic anhydride to aquatic microorganisms is assessed via read-across from its hydrolytic transformation product succinic acid. (europa.eu)
  • In order to ward off these infections, this paper explores the immobilization of triethoxysilylpropyl succinic anhydride (TESPSA, TSP) silane onto dental implants, and the interaction of two distinct monospecies biofilms and an oral plaque with the coated titanium samples. (upc.edu)
  • Activated sludge obtained from a sewage treatment plant was exposed in a 3-hour respiration inhibition test to nominal concentrations of 0 (control), 7.7, 19.3, 48.2, 120.6 and 301.5 mg succinic acid/L. The test design included duplicate samples and followed the OECD 209 guideline (version 4 April 1984). (europa.eu)
  • In the laboratory, this material can be prepared by dehydration of succinic acid. (wikipedia.org)
  • Industrially, succinic anhydride is prepared by catalytic hydrogenation of maleic anhydride. (wikipedia.org)
  • Maleic anhydride undergoes the Alder-ene reaction with alkenes to give alkenylsuccinic anhydrides. (wikipedia.org)
  • Maleic anhydride undergoes a similar reaction with polyisobutylene to give polyisobutylenylsuccinic anhydride, a common building block chemical in the petroleum additives industry. (wikipedia.org)
  • Maleic anhydride adduct of butadiene styrene. (fda.gov)
  • The chips were reacted with acetic, succinic, maleic and phthalic anhydride at constant temperature for 3 hours then, hot pressed at 150 °C by using phenol for. (irg-wp.com)
  • Copolymer of divinyl ether and maleic anhydride that acts as an immunostimulant with antineoplastic and anti-infective properties. (lookformedical.com)
  • Asia-pacific is one of the largest Maleic Anhydride producer in the world accounting for more than 75% of production capacity and 60% of the global demand. (prismaneconsulting.com)
  • China is the biggest producer of maleic anhydride in Asia Pacific accounting for more than 70% of the regional maleic anhydride production. (prismaneconsulting.com)
  • With the increasing demand for maleic anhydride from China and other Southeast Asian countries, the Maleic Anhydride market in Asia Pacific is poised to register a CAGR of 5.2% to cross 2,200 kilo tons by 2032 from the current demand of around 1,500 kilo tons. (prismaneconsulting.com)
  • In the long-term forecast, the demand growth for maleic anhydride in the region is estimated to grow on account of increased growth from UPR and other derivatives like 1, 4 butanediol, lubricating oil additives, copolymers, maleic acid, fumaric acid, and agricultural chemicals. (prismaneconsulting.com)
  • Furthermore, as most automotive, and other downstream derivative companies are shifting their base to Asian Countries like China, India, Vietnam, and other Southeast Asian Countries, regional maleic anhydride demand will also is estimated to exhibit strong growth in the coming year. (prismaneconsulting.com)
  • In 2022, Asia Pacific maleic anhydride capacity stood at 2,800 kilo tons, an increase of almost 450 kilo tons from 2016. (prismaneconsulting.com)
  • China is the largest market for maleic anhydride and has around 50 small scale and large-scale producers with a total production capacity of 2300 kilo tons as of 2022. (prismaneconsulting.com)
  • Northeast Asia is the biggest maleic anhydride producer in Asia Pacific accounting for more than 90% of the regional capacity on the back of presence of major maleic anhydride producers in China and Taiwan. (prismaneconsulting.com)
  • Chinese Maleic Anhydride market is experiencing oversupply situation and no further major expansions are estimated till 2025. (prismaneconsulting.com)
  • Most of the demand for maleic anhydride in the region is from unsaturated polyester resins (UPR) with a share of more than 64% of the total regional maleic anhydride demand followed by 1, 4 butanediols with a 10% market share. (prismaneconsulting.com)
  • Maleic Anhydride demand is expected to be strong especially in countries with large populations such as China, India, Indonesia, Thailand, Philippines, and Vietnam. (prismaneconsulting.com)
  • Further the increase in living standards and increasing purchasing power among consumers due to economic growth will keep the regional maleic anhydride demand high. (prismaneconsulting.com)
  • Maleic Anhydride demand in the region is projected strong growth owing to shift of automobile production away from the mature markets to the developing regions in Asia-Pacific. (prismaneconsulting.com)
  • In terms of Maleic Anhydride market by country, China dominates the regional market accounting for around 72% in 2022, which translates to around 1,050 kilo tons. (prismaneconsulting.com)
  • The Maleic Anhydride market in China is estimated to grow at a CAGR of 5% in the forecast period to reach 1,650 kilo tons by 2032. (prismaneconsulting.com)
  • Malaysia is the second biggest maleic anhydride market in Asia Pacific accounting for around 9% of the regional market. (prismaneconsulting.com)
  • Japan and India together account for more than 16% of the regional maleic anhydride market. (prismaneconsulting.com)
  • In the long term forecast, India is projected to register highest CAGR of 5.7% on the back of increasing demand of maleic anhydride from end use industries such as Construction, Automotive and others. (prismaneconsulting.com)
  • Method for preparing maleic anhydride and pressure drop radial isothermal reactor_Changzhou Ruihua Chemical Engineering Technology Co., Ltd. (ruihuaeng.com)
  • W.H.G. was performed with cyclic anhydrides (succinic, maleic and glutaric) assisted by microwave radiation. (ucsc.cl)
  • Modified lignin based on succinic-, maleic- and glutaric-anhydride is expected to play a key role in the design of novel bio-based dispersants for drilling-mud applications. (ucsc.cl)
  • Stability and bioaccessibility of curcumin emulsions stabilized by casein hydrolysates after maleic anhydride acylation and pullulan glycation. (translationandethics.com)
  • Dover Chemical Corp. now has polyisobutylene succinic anhydride (PIBSA) and derivative products in commercial production at its Hammond, IN, facility. (adhesivesmag.com)
  • This colorless solid is the acid anhydride of succinic acid. (wikipedia.org)
  • In the laboratory, this material can be prepared by dehydration of succinic acid. (wikipedia.org)
  • Succinic anhydride hydrolyzes readily to give succinic acid: (CH2CO)2O + H2O → (CH2CO2H)2 With alcohols (ROH), a similar reaction occurs, delivering the monoester: (CH2CO)2O + ROH → RO2CCH2CH2CO2H Succinic anhydride is used in acylations under Friedel-Crafts conditions, as illustrated by the industrial route to the drug Fenbufen. (wikipedia.org)
  • The pKa value for succinic acid was determined to be 4.67 at 20 °C, which corresponds to a weak acid. (europa.eu)
  • Succinic anhydride is inherently unstable in aqueous media and rapidly hydrolyzes to form succinic acid. (europa.eu)
  • The dissociation constant of succinic acid was reported as 4.67 at 20 °C. (europa.eu)
  • Phthalic acid anhydrides. (lookformedical.com)
  • CAS : 924-88-9 formula : C10H18O4 molecular weight : 202.25 Chinese name : succinate two isopropyl succinate two isopropyl English title : kSuccinic acid, a ester Succinic acid, a ester traits Description : colorless and transparent liquid. (acadiasi.ro)
  • 100 = 0.509% succinic acid 3. (acadiasi.ro)
  • 2-Phenyl-succinic acid. (acadiasi.ro)
  • Now you can calculate its boiling point … Chemsrc provides Succinic acid(CAS#:110-15-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. (acadiasi.ro)
  • Butanedioic acid, phenyl-Succinic acid, phenyl-2-Phenylsuccinate. (acadiasi.ro)
  • Succinic acid (butanedioic acid) is a dicarboxylic acid that occurs naturally in plant and animal tissues. (acadiasi.ro)
  • In this role, the anhydride is proposed to form an ester with the hydroxyl groups on the cellulose fibers. (wikipedia.org)
  • "In this work, a novel hydrophilic phytosterol derivative PPGS was successfully synthesized by a two-step sequence of chemical acylation of phytosterols with succinic anhydride followed by lipase-catalyzed esterification of PEG 1000 with PSHS ​[phytosteryl hemisuccinate] ," ​ wrote He and his colleagues. (nutraingredients.com)
  • An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Succinic anhydride (108-30-5). (nih.gov)
  • Succinic anhydride, is an organic compound with the molecular formula (CH2CO)2O. (wikipedia.org)
  • According to the Handbook of Physical Properties of Organic Chemicals the vapour pressure of succinic anhydride was extrapolated from an experimental data range above or below 25 °C to 2.86 x 10 -6 mm Hg at 25 °C. (europa.eu)
  • Succinic anhydride is a widely used organic chemical raw material. (ruihuaeng.com)
  • The conjugation of succinic anhydride to the SCNP surface provides negative surface charges that have been shown to increase the targeting ability of SCNPs to Plasmodium berghei ookinetes. (ibecbarcelona.eu)
  • Genetic Toxicity Evaluation of Succinic Anhydride in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)