Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
Health facilities providing therapy and/or rehabilitation for substance-dependent individuals. Methadone distribution centers are included.
Disorders related to substance abuse.
Abuse of children in a family, institutional, or other setting. (APA, Thesaurus of Psychological Index Terms, 1994)
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
Sexual maltreatment of the child or minor.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to substance abuse and mental health. It is commonly referred to by the acronym SAMHSA. On 1 October 1992, the United States Alcohol, Drug Abuse, and Mental Health Administration (ADAMHA) became SAMHSA.
A specialized residential treatment program for behavior disorders including substance abuse. It may include therapeutically planned group living and learning situations including teaching of adaptive skills to help patient functioning in the community. (From Kahn, A. P. and Fawcett, J. Encyclopedia of Mental Health, 1993, p320.)
The co-existence of a substance abuse disorder with a psychiatric disorder. The diagnostic principle is based on the fact that it has been found often that chemically dependent patients also have psychiatric problems of various degrees of severity.
The excessive use of marijuana with associated psychological symptoms and impairment in social or occupational functioning.
A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Drugs obtained and often manufactured illegally for the subjective effects they are said to produce. They are often distributed in urban areas, but are also available in suburban and rural areas, and tend to be grossly impure and may cause unexpected toxicity.
Deliberate severe and repeated injury to one domestic partner by the other.
Emotional, nutritional, financial, or physical maltreatment, exploitation, or abandonment of the older person generally by family members or by institutional personnel.
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
Disorders related or resulting from abuse or mis-use of opioids.
Persons who were child victims of violence and abuse including physical, sexual, or emotional maltreatment.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A branch of law that defines criminal offenses, regulates the apprehension, charging and trial of suspected persons, and fixes the penalties and modes of treatment applicable to convicted offenders.
Organized services to provide mental health care.
Disorders related or resulting from use of cocaine.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
A violation of the criminal law, i.e., a breach of the conduct code specifically sanctioned by the state, which through its administrative agencies prosecutes offenders and imposes and administers punishments. The concept includes unacceptable actions whether prosecuted or going unpunished.
Persons who have committed a crime or have been convicted of a crime.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Individual or group aggressive behavior which is socially non-acceptable, turbulent, and often destructive. It is precipitated by frustrations, hostility, prejudices, etc.
Disorders related or resulting from use of amphetamines.
Persons who have no permanent residence. The concept excludes nomadic peoples.
The observable, measurable, and often pathological activity of an organism that portrays its inability to overcome a habit resulting in an insatiable craving for a substance or for performing certain acts. The addictive behavior includes the emotional and physical overdependence on the object of habit in increasing amount or frequency.
A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Penal institutions, or places of confinement for war prisoners.
Insurance providing benefits to cover part or all of the psychiatric care.
Component of the NATIONAL INSTITUTES OF HEALTH. It supports a comprehensive research portfolio that focuses on the biological, social, behavioral and neuroscientific bases of drug abuse on the body and brain as well as its causes, prevention, and treatment. NIDA, NIAAA, and NIMH were created as coequal institutes within the Alcohol, Drug Abuse and Mental Health Administration in 1974. It was established within the NATIONAL INSTITUTES OF HEALTH in 1992.
Undertaking a task involving a challenge for achievement or a desirable goal in which there is a lack of certainty or a fear of failure. It may also include the exhibiting of certain behaviors whose outcomes may present a risk to the individual or to those associated with him or her.
Psychotherapeutic technique which emphasizes socioenvironmental and interpersonal influences in the resocialization and rehabilitation of the patient. The setting is usually a hospital unit or ward in which professional and nonprofessional staff interact with the patients.
Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.
Abuse, overuse, or misuse of a substance by its injection into a vein.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Housing for groups of patients, children, or others who need or desire emotional or physical support. They are usually established as planned, single housekeeping units in residential dwellings that provide care and supervision for small groups of residents, who, although unrelated, live together as a family.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
A form of group psychotherapy. It involves treatment of more than one member of the family simultaneously in the same session.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
People who take drugs for a non-therapeutic or non-medical effect. The drugs may be legal or illegal, but their use often results in adverse medical, legal, or social consequences for the users.
A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
Specialized residences for persons who do not require full hospitalization, and are not well enough to function completely within the community without professional supervision, protection and support.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Any violation of established legal or moral codes in respect to sexual behavior.
Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.
The antisocial acts of children or persons under age which are illegal or lawfully interpreted as constituting delinquency.
A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist.
Control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs. This includes regulations concerned with the manufacturing, dispensing, approval (DRUG APPROVAL), and marketing of drugs.
The physician's inability to practice medicine with reasonable skill and safety to the patient due to the physician's disability. Common causes include alcohol and drug abuse, mental illness, physical disability, and senility.
Individuals subjected to and adversely affected by criminal activity. (APA, Thesaurus of Psychological Index Terms, 1994)
Elements of limited time intervals, contributing to particular results or situations.
A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.
A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Any observable response or action of an adolescent.
Health care services provided to patients on an ambulatory basis, rather than by admission to a hospital or other health care facility. The services may be a part of a hospital, augmenting its inpatient services, or may be provided at a free-standing facility.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The giving of advice and assistance to individuals with educational or personal problems.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.
Diagnostic, therapeutic and preventive mental health services provided for individuals in the community.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Drugs that cannot be sold legally without a prescription.
Deliberate, often repetitive physical, verbal, and/or other types of abuse by one or more members against others of a household.
The use of community resources, individual case work, or group work to promote the adaptive capacities of individuals in relation to their social and economic environments. It includes social service agencies.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
A composition in prose or verse presenting in dialogue or pantomime a story involving various characters, usually intended to be acted on a stage and to be regarded as a form of entertainment. (From Random House Unabridged Dictionary, 2d ed)
Facilities which administer the delivery of psychologic and psychiatric services to people living in a neighborhood or community.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Federal, state, or local government organized methods of financial assistance.
Organized efforts to insure obedience to the laws of a community.
A health care system which combines physicians, hospitals, and other medical services with a health plan to provide the complete spectrum of medical care for its customers. In a fully integrated system, the three key elements - physicians, hospital, and health plan membership - are in balance in terms of matching medical resources with the needs of purchasers and patients. (Coddington et al., Integrated Health Care: Reorganizing the Physician, Hospital and Health Plan Relationship, 1994, p7)
A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)
Social and economic factors that characterize the individual or group within the social structure.
Disorders related to or resulting from abuse or mis-use of alcohol.
Inhaling and exhaling the smoke from CANNABIS.
Social welfare organizations with programs designed to assist individuals in need.
Illicit use of chemicals and products whose vapors can be inhaled to produce a rapid mind-altering effect. Inhalants include aerosols, gases, and volatile solvents that are often inhaled repeatedly to achieve the short-lived intoxicating effect.
The inability of a health professional to provide proper professional care of patients due to his or her physical and/or mental disability.
Medical treatment for opioid dependence using a substitute opiate such as METHADONE or BUPRENORPHINE.
Those disorders that have a disturbance in mood as their predominant feature.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
Organized services to provide immediate psychiatric care to patients with acute psychological disturbances.
Child with one or more parents afflicted by a physical or mental disorder.
A form of therapy in which two or more patients participate under the guidance of one or more psychotherapists for the purpose of treating emotional disturbances, social maladjustments, and psychotic states.
Strong dependence, both physiological and emotional, upon heroin.
Cultural and linguistic competence is a set of congruent behaviors, attitudes, and policies that come together in a system, agency, or among professionals that enables effective work in cross-cultural situations. Competence implies the capacity to function effectively as an individual and an organization within the context of the cultural beliefs, behaviors, and needs presented by consumers and their communities.
A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.
The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive care and services from the health care system. Factors influencing this ability include geographic, architectural, transportational, and financial considerations, among others.
The seeking and acceptance by patients of health service.
Unlawful sexual intercourse without consent of the victim.
A legal requirement that designated types of information acquired by professionals or institutions in the course of their work be reported to appropriate authorities.
Tobacco used to the detriment of a person's health or social functioning. Tobacco dependence is included.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
The use of force or intimidation to obtain compliance.
Organized services to provide health care to women. It excludes maternal care services for which MATERNAL HEALTH SERVICES is available.
Diagnostic, therapeutic and preventive health services provided for individuals in the community.
Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.
Persons living in the United States of Mexican (MEXICAN AMERICANS), Puerto Rican, Cuban, Central or South American, or other Spanish culture or origin. The concept does not include Brazilian Americans or Portuguese Americans.
Discontinuance of care received by patient(s) due to reasons other than full recovery from the disease.
Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.
The plant genus in the Cannabaceae plant family, Urticales order, Hamamelidae subclass. The flowering tops are called many slang terms including pot, marijuana, hashish, bhang, and ganja. The stem is an important source of hemp fiber.
Stress wherein emotional factors predominate.
Programs in which participation is required.
Sexual activities of humans.
Individual members of North American ethnic groups with ancient historic ancestral origins in Asia.
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
Low-molecular-weight end products, probably malondialdehyde, that are formed during the decomposition of lipid peroxidation products. These compounds react with thiobarbituric acid to form a fluorescent red adduct.
The unsuccessful attempt to kill oneself.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
An act performed without delay, reflection, voluntary direction or obvious control in response to a stimulus.
A cabinet department in the Executive Branch of the United States Government concerned with administering those agencies and offices having programs pertaining to health and human services.
Psychotherapy used specifically for unmarried couples, of mixed or same sex. (From APA, Thesaurus of Psychological Index Terms, 1994)
The act of killing oneself.
The state wherein the person is well adjusted.
Federal program, created by Public Law 89-97, Title XIX, a 1965 amendment to the Social Security Act, administered by the states, that provides health care benefits to indigent and medically indigent persons.
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
The application of modern theories of learning and conditioning in the treatment of behavior disorders.
Organic matter in a state of advanced decay, after passing through the stages of COMPOST and PEAT and before becoming lignite (COAL). It is composed of a heterogenous mixture of compounds including phenolic radicals and acids that polymerize and are not easily separated nor analyzed. (E.A. Ghabbour & G. Davies, eds. Humic Substances, 2001).
Persons who receive ambulatory care at an outpatient department or clinic without room and board being provided.
Agents inhibiting the effect of narcotics on the central nervous system.
A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed)
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A change or shift in personnel due to reorganization, resignation, or discharge.
Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Group composed of associates of same species, approximately the same age, and usually of similar rank or social status.
Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.
The misuse of phencyclidine with associated psychological symptoms and impairment in social or occupational functioning.
Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
Former members of the armed services.
Health services required by a population or community as well as the health services that the population or community is able and willing to pay for.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
A generic term for the treatment of mental illness or emotional disturbances primarily by verbal or nonverbal communication.
Assessment of psychological variables by the application of mathematical procedures.
A social group consisting of parents or parent substitutes and children.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Human males as cultural, psychological, sociological, political, and economic entities.
Theoretical representations and constructs that describe or explain the structure and hierarchy of relationships and interactions within or between formal organizational entities or informal social groups.
The inhabitants of a city or town, including metropolitan areas and suburban areas.
Voluntary cooperation of the patient in following a prescribed regimen.
Support systems that provide assistance and encouragement to individuals with physical or emotional disabilities in order that they may better cope. Informal social support is usually provided by friends, relatives, or peers, while formal assistance is provided by churches, groups, etc.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Health insurance plans intended to reduce unnecessary health care costs through a variety of mechanisms, including: economic incentives for physicians and patients to select less costly forms of care; programs for reviewing the medical necessity of specific services; increased beneficiary cost sharing; controls on inpatient admissions and lengths of stay; the establishment of cost-sharing incentives for outpatient surgery; selective contracting with health care providers; and the intensive management of high-cost health care cases. The programs may be provided in a variety of settings, such as HEALTH MAINTENANCE ORGANIZATIONS and PREFERRED PROVIDER ORGANIZATIONS.
Conversations with an individual or individuals held in order to obtain information about their background and other personal biographical data, their attitudes and opinions, etc. It includes school admission or job interviews.
Statistical interpretation and description of a population with reference to distribution, composition, or structure.
Inhaling and exhaling the smoke of burning TOBACCO.
The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
The amounts spent by individuals, groups, nations, or private or public organizations for total health care and/or its various components. These amounts may or may not be equivalent to the actual costs (HEALTH CARE COSTS) and may or may not be shared among the patient, insurers, and/or employers.
A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)
Persistent and disabling ANXIETY.
Application of statistical procedures to analyze specific observed or assumed facts from a particular study.
The level of governmental organization and function below that of the national or country-wide government.
A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Financial assistance provided by the government to indigent families with dependent children who meet certain requirements as defined by the Social Security Act, Title IV, in the U.S.
The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.
Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
Behaviors which are at variance with the expected social norm and which affect other individuals.
The study of significant causes and processes in the development of mental illness.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Persons living in the United States having origins in any of the black groups of Africa.
A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships.
State plans prepared by the State Health Planning and Development Agencies which are made up from plans submitted by the Health Systems Agencies and subject to review and revision by the Statewide Health Coordinating Council.
Fetal and neonatal addiction and withdrawal as a result of the mother's dependence on drugs during pregnancy. Withdrawal or abstinence symptoms develop shortly after birth. Symptoms exhibited are loud, high-pitched crying, sweating, yawning and gastrointestinal disturbances.
Techniques used in studying bacteria.
The reciprocal interaction of two or more persons.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Outside services provided to an institution under a formal financial agreement.
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)
A traditional term for all the activities which a physician or other health care professional normally performs to insure the coordination of the medical services required by a patient. It also, when used in connection with managed care, covers all the activities of evaluating the patient, planning treatment, referral, and follow-up so that care is continuous and comprehensive and payment for the care is obtained. (From Slee & Slee, Health Care Terms, 2nd ed)
Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.
Hospital department responsible for the organization and administration of psychiatric services.
Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.

A practical approach to determine cutoff concentrations for opiate testing with simultaneous detection of codeine, morphine, and 6-acetylmorphine in urine. (1/1192)

BACKGROUND: Both the Department of Defense (DoD) and the Department of Health and Human Services (DHHS) currently require two confirmation tests to verify use of heroin, one test for total morphine and a separate test for 6-acetylmorphine (6-AM). Our aim was to determine appropriate free-codeine, free-morphine, and 6-AM cutoff concentrations that could be substituted for total-morphine, total-codeine, and 6-AM cutoff concentrations and to develop a less labor-intensive method for measuring codeine, morphine, and 6-AM. METHODS: Urine samples containing opiates were extracted, derivatized, and analyzed using gas chromatography-mass spectrometry with selective ion monitoring. RESULTS: The limits of detection for codeine, morphine, and 6-AM were 6, 5, and 0.5 microg/L, respectively. Recoveries were >90%. Quantification was linear over the concentration range of 6-1000 microg/L for codeine, 5-5000 microg/L for morphine, and 0.5-800 microg/L for 6-AM. Cutoff concentrations for confirmation of opiates were 100, 100, and 10 microg/L for free codeine, free morphine, and 6-AM. CONCLUSION: The proposed cutoff concentrations for free morphine and 6-AM provide better detection windows for morphine and heroin use than the cutoff concentrations for total morphine and 6-AM used at present. Detection of free codeine, instead of total codeine, simplifies interpretation of codeine use. The single-extraction method enables simultaneous, less labor-intensive analysis of morphine, codeine, and 6-AM.  (+info)

Accuracy of five on-site immunoassay drugs-of-abuse testing devices. (2/1192)

Many current "on-site" urine drug-testing products claim performance equivalent to laboratory testing. Five commercially available products (PharmScreen, Roche TestCup, Accusign DOA 2, Status DS, and American Bio Medica-Rapid Drug Screen) were challenged with quality-control specimens of known drug metabolite concentrations, 25% above and 25% below the SAMHSA cutoffs, and with known positive and negative donor specimens previously analyzed by immunoassay and gas chromatography-mass spectrometry. The results indicate discrepancies between claims and performance for all products, particularly with amphetamines. The implications for employer-based drug testing are discussed.  (+info)

Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. (3/1192)

OBJECTIVES: This study (1) determined levels of various tobacco alkaloids in commercial tobacco products. (2) determined urinary concentrations, urinary excretion, and half-lives of the alkaloids in humans; and (3) examined the possibility that urine concentrations of nicotine-related alkaloids can be used as biomarkers of tobacco use. METHODS: Nicotine intake from various tobacco products was determined through pharmacokinetic techniques. Correlations of nicotine intake with urinary excretion and concentrations of anabasine, anatabine, nornicotine, nicotine, and cotinine were examined. By using urinary excretion data, elimination half-lives of the alkaloids were calculated. RESULTS: Alkaloid levels in commercial tobacco products, in milligrams per gram, were as follows: nicotine, 6.5 to 17.5; nornicotine, 0.14 to 0.66; anabasine, 0.008 to 0.030; and anatabine, 0.065 to 0.27. Measurable concentrations of all alkaloids were excreted in the urine of most subjects smoking cigarettes, cigars, and pipes and using smokeless tobacco. Correlations between nicotine intake and alkaloid concentrations were good to excellent. CONCLUSIONS: Anabasine and anatabine, which are present in tobacco but not in nicotine medications, can be used to assess tobacco use in persons undergoing nicotine replacement therapy.  (+info)

The measurement of nitrite in adulterated urine samples by high-performance ion chromatography. (4/1192)

With the increased availability of nitrite-containing commercial products that are used for the adulteration of urine samples in the workplace, it is necessary for laboratories to be able to detect and confirm the presence of nitrite in these samples. We have developed a method to confirm the presence of nitrite in urine samples. The method uses the IonPac AS 14 analytical column with the Dionex series 45001 Bio LC system equipped with an anion self-generating suppressor and conductivity detector. Using a single-point calibration, the method is linear and accurately quantitates nitrite to 12,000 microg/mL. The limit of detection is 30 microg/mL, and the day-to-day precision of the assay has a coefficient of variation (CV) of 4.3% at 1200 microg/mL and 3.8% at 2700 microg/mL of nitrite.  (+info)

Nail analysis for drugs of abuse: extraction and determination of cannabis in fingernails by RIA and GC-MS. (5/1192)

Fingernail clippings were evaluated as analytical specimens for the detection and quantitation of cannabinoids. Specimens were obtained from consenting adults attending a drug clinic, along with information concerning the drugs which they had used over the previous six months. Methods for the surface decontamination and extraction of the specimens were evaluated. Detergent, water, and methanol washes followed by alkaline hydrolysis and liquid-liquid extraction were selected for use in the study. Extracts were analyzed by radioimmunoassay (RIA) and gas chromatography-mass spectrometry (GC-MS) to detect and quantitate cannabinoids present in fingernail clippings. Positive RIA results were obtained from specimens from six known cannabis users. The mean cannabinoid concentration in fingernail clippings determined by RIA was 1.03 ng/mg. Using GC-MS, the mean delta9-tetrahydrocannabinol concentration in fingernail clippings from a further 14 known cannabis users was 1.44 ng/mg. Using GC-MS, the average 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid concentration in fingernail clippings from three known cannabis users extracted in acidic pH was 19.85 ng/mg. Based on these results, fingernails are potentially useful biological specimens for the detection of past cannabis use in cases of medicolegal interest.  (+info)

Detection of 6-acetylmorphine in vitreous humor and cerebrospinal fluid--comparison with urinary analysis for proving heroin administration in opiate fatalities. (6/1192)

The concentrations of morphine and 6-acetylmorphine (6-AM) in urine, cerebrospinal fluid (CSF), and vitreous humor (VH) and the morphine concentrations in blood were determined by gas chromatography-mass spectrometry for 29 fatalities after abuse of heroin either alone or in combination with alcohol and other drugs. 6-AM was found above a quantitation limit of 1 ng/mL in urine in 89% of the cases, in CSF in 68% of the cases, and in VH in 75% of the cases. The 6-AM concentrations in CSF (mean, 10 ng/mL) and VH (mean, 17 ng/mL) were in general much smaller than in urine (mean, 170 ng/mL); therefore, the different pharmacokinetic behavior of the fluids is discussed. There is no uniformity between the three fluids with respect to the presence or absence of 6-AM. Therefore, CSF or VH may be used as complementary or alternative materials to urine in order to prove heroin uptake in opiate fatalities.  (+info)

Amphetamine and fenproporex levels following multidose administration of fenproporex. (7/1192)

Drugs that are metabolized to amphetamine or methamphetamine are potentially of significant concern in the interpretation of positive drug-testing results for amphetamines. A number of different drugs have been reported to produce amphetamine in the urine of users. One of these compounds, fenproporex, has been shown to be metabolized to amphetamine, and previous reports indicated the parent compound could be detected at low levels for up to 48 h. Administration of fenproporex for seven days (one 10-mg dose per day) to five healthy volunteers resulted in amphetamine being detected in the urine of all subjects. Peak concentrations of amphetamine ranged from approximately 2850 to 4150 ng/mL. Amphetamine could be detected (> or = 5 ng/mL) in the urine for up to nearly 170 h after the last dose. Analysis of the metabolically produced amphetamine showed the presence of both enantiomers, which can be helpful in the differentiation of some illicit amphetamine use from the use of this precursor drug. In addition, evaluation of the enantiomeric composition of the metabolite (amphetamine) can be a valuable tool in the interpretation of time since last dose. More significantly, all samples that contained amphetamine at a concentration of > or = 500 ng/mL were shown to also contain detectable amounts of the parent compound.  (+info)

Comparison of solid-phase extraction and supercritical fluid extraction for the analysis of morphine in whole blood. (8/1192)

A comparative study of the quantitative determination of morphine in whole blood using solid-phase extraction (SPE) and supercritical fluid extraction (SFE) is described. Comparative studies were made of the two techniques for the extraction of morphine from authentic forensic blood specimens. Quantitative results indicate that morphine levels measured using SPE correspond well to morphine levels produced using SFE. The two techniques are therefore comparable, although SFE is faster and cleaner and extracts may be produced with higher analyte recoveries than with SPE. This paper presents a comparison of the two techniques and the morphine concentrations determined in blood.  (+info)

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References:. -Moeller KE, Kissack JC, Atayee RS, Lee KC. Clinical Interpretation of Urine Drug Tests: What Clinicians Need to Know About Urine Drug Screens. Mayo Clin Proc. 2017 May;92(5):774-96. -Nelson ZJ, Stellpflug SJ, Engebretsen KM. What Can a Urine Drug Screening Immunoassay Really Tell Us? J Pharm Pract. 2016 Oct;29(5):516-26. -Johnson-Davis KL, Sadler AJ, Genzen JR. A Retrospective Analysis of Urine Drugs of Abuse Immunoassay True Positive Rates at a National Reference Laboratory. Journal of Analytical Toxicology. 2016 Mar;40(2):97-107. -Saitman A, Park H-D, Fitzgerald RL. False-positive interferences of common urine drug screen immunoassays: a review. Journal of Analytical Toxicology. 2014 Sep;38(7):387-96. -Hoffman, Robert, Howland, Mary Ann, Lewin, Neal,Nelson, Lewis, Goldfrank, Lewis, Flomenbaum, Neal E. Goldfranks Toxicologic Emergencies, 10th Edition. New York: McGraw-Hill Education; 2015. Print. -Lin C-N, Strathmann FG. Elevated urine zinc concentration reduces the detection of ...
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26] Immunological, pharmacological, and electrophysiological detection of T-cell-modulating properties of substances of abuse. ... 26] Immunological, pharmacological, and electrophysiological detection of T-cell-modulating properties of substances of abuse. ... 26] Immunological, pharmacological, and electrophysiological detection of T-cell-modulating properties of substances of abuse. ... 26] Immunological, pharmacological, and electrophysiological detection of T-cell-modulating properties of substances of abuse. ...
Substance Abuse Detection. Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. ... Lie Detection. Ascertaining of deception through detection of emotional disturbance as manifested by changes in physiologic ... Summary of "Detection of Pseudogymnoascus destructans during Summer on Wisconsin Bats.". White-. nose syndrome (WNS) affects ... Detection of Pseudogymnoascus destructans during Summer on Wisconsin Bats.. 07:00 EST 3rd January 2019 , BioPortfolio ...
Substance Abuse Detection. Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. ... in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection ... assay for detection of carbapenemase activity in the BDPCPO panel displays high sensitivity for carbapenemase detection while ... Detection of carbapenemase-producing Enterobacterales and the BD Phoenix CPO Detect panel.. 08:00 EDT 17th July 2019 , ...
Palabras clave : Emergencies; Emergency medical services; Substance abuse detection; Psychotropic drugs; Hypnotics and ... alone or in combination with other substances. The aim of the research was to obtain information about the consumption of ... obtained from Emergency Indicator related to the use of psychoactive substances of the National Observatory on Drugs. There ... Sedatives; Benzodiazepines; Drug Overdose; Suicide Attempted; Substance-Related Disorders; Self Medication. · resumen en ...
Achiral and chiral semi-micro column high-performance liquid chromatographic methods with fluorescence detection to determine ... Substance Abuse Detection / methods*. Chemical. Reg. No./Substance: 300-62-9/Amphetamine; 537-46-2/Methamphetamine ... Achiral and chiral semi-micro column high-performance liquid chromatographic methods with fluorescence detection to determine ... Quantification of methamphetamine, amphetamine and enantiomers by semi-micro column HPLC with fluorescence detection; ...
Substance Abuse Detection / economics*. United States. Grant Support. ID/Acronym/Agency: AA013925/AA/NIAAA NIH HHS; R01 ... 23164318 - Active case detection in national visceral leishmaniasis elimination programs in bangla.... 12500348 - Using ...
  • The AUDIT (alcohol use disorders identification test) is the best test for screening because it detects hazardous drinking and alcohol abuse. (medscape.com)
  • [ 36 ] The co-occurring disorders of PTSD and alcohol abuse are expressed differently between the genders. (medscape.com)
  • The clinical profession should consider measures to improve detection and referral of patients with substance abuse disorders. (hindawi.com)
  • Prevalence of substance abuse disorders is higher in population treated in Healthcare Facilities than in the general population. (hindawi.com)
  • This long-awaited follow-up to the classic text Clinical Manual of Adolescent Substance Abuse Treatment presents the latest research on substance use and substance use disorders (SUDs) in adolescents 12-18 and emerging adults 18-25 years of age. (appi.org)
  • Because youth are not simply miniature adults, the book uses a developmentally informed approach to understand the onset of substance use and the trajectory to SUD and behavioral addictive disorders. (appi.org)
  • With the alarming prevalence of substance use and mental health disorders in the legal profession, it is imperative that we are all armed with the knowledge and insight of how to approach someone who may be struggling. (nacle.com)
  • Management of acute pain following surgery or trauma requiring opioid treatment can be particularly challenging in patients with substance use disorders. (painweek.org)
  • In this book, Dr. Gerald Juhnke presents an innovative, practical model to be used in the assessment and diagnosing of substance abuse and related co-morbid disorders. (routledge.com)
  • The DSM-IV-TR-Multiaxial System and Common Substance-Related Disorders. (routledge.com)
  • Through early detection of a dual diagnosis for substance abuse and addiction and co-occurring mental health disorders is crucial. (tapartnership.org)
  • SAMHSA - the Substance Abuse and Mental Health Services Administration - reports that the most effective and efficient dual diagnosis regimen will treat both the substance use issues and mental health disorders at the same time. (tapartnership.org)
  • This is because mental health disorders were exclusively treated in psychiatric environments while substance abuse and addiction were managed at drug and alcohol rehabilitation facilities. (tapartnership.org)
  • Early detection and education can help a person deal properly with eating disorders and substance abuse. (utpb.edu)
  • Among the disorders related to the misuse of these substances, a distinction is made between substance abuse and substance dependence. (healthyplace.com)
  • A descriptive cross-sectional study was done by analyzing 3,089 emergencies related to consumption of hypnotics and sedatives, obtained from Emergency Indicator related to the use of psychoactive substances of the National Observatory on Drugs. (isciii.es)
  • BI have proved to be beneficial for male individuals and those patients who do not abuse other psychoactive substances. (frontiersin.org)
  • A one-page paper and pencil test that identifies people who suffer from substance dependence. (directoryhealthy.com)
  • Panic disorder, generalized anxiety disorder, social phobia, dysthymic disorder, major depression, bipolar mania, or primary (idiopathic) insomnia: Alcohol abuse or dependence might reflect self-treatment for these conditions. (medscape.com)
  • Dr. Juhnke's work on the assessment and diagnosis of substance abuse and dependence brings together a wealth of knowledge and application in a manner both needed and never before provided in a single text. (routledge.com)
  • Over time, alcohol or drug abuse can lead to dependence and a co-occurring mental health/substance use disorder . (recovery.org)
  • Find out the difference between substance abuse and substance dependence and the characteristics of alcoholism. (healthyplace.com)
  • Below we will provide a breakdown of each sample type and accompanying detection windows for the presence of illicit substances. (randox.com)
  • The current focus of my research is the development of methods to improve the detection and identification of illicit substances such as drugs of abuse. (wcupa.edu)
  • AACAP Official Action: Practice parameter for the assessment and treatment of children and adolescents with substance use disorder. (aerzteblatt.de)
  • Recognized substance abuse patients tend to have an antisocial personality disorder (type 2 alcoholism, characterized by an association with criminal behavior [sociopathy], onset in teen years, and drinking to get high), while those whose diagnosis is missed tend to have depression or anxiety. (medscape.com)
  • In fact, a substance abuse disorder is seen in nearly 60% of individuals with bipolar disorder. (medscape.com)
  • Of particular importance is the common concurrence of posttraumatic stress disorder (PTSD) and alcohol abuse. (medscape.com)
  • This occurs when you are struggling with a substance use disorder as well as a co-occurring mental health disorder. (tapartnership.org)
  • On the other hand, having a mental health disorder could compel you to start taking these substances as a form of self-medication. (tapartnership.org)
  • In the context of addiction treatment and recovery, it is a dual diagnosis for both substances abuse and a co-occurring mental health disorder or medical illness. (tapartnership.org)
  • People suffering from post-traumatic stress disorder (PTSD) commonly abuse substances as a form of self-medication. (recovery.org)
  • Such behavior is indicative of a mental disorder which can turn an illegal or a legal substance into a "drug" and which requires psychiatric medical treatment. (healthyplace.com)
  • This important CLE program will take a look at famous people suffering from mental illness and substance abuse and how it relates to the Legal Profession. (nacle.com)
  • This vitally important CLE program focuses on substance abuse and related issues which affect a surprising and disproportionate number of legal professionals. (nacle.com)
  • Lateral immunoassay tests indicate a level of substance present in urine based on use of substances in a previous (approximate) 72 hour period. (accu-metrics.com)
  • Urine screening is the usual method of detection. (rush.edu)
  • Incidence and predictors of screen failures due to positive urine tests for alcohol, drugs of abuse, and cotinine among normal healthy research volunteers (NHRVs): analysis of data from 687 NHRVs screened at a large clinical pharmacology unit in the United States. (rush.edu)
  • Screening tests to determine levels of alcohol or the presence of drugs of abuse in blood and urine are commonly used with diagnostic purposes, especially when it is suspected that the patient's symptoms or the reason for admission is connected with the admission. (hindawi.com)
  • Variation of symptoms with the type of consumption and doctor's interest in ordering urine toxicology may be barriers to diagnosis of substance abuse. (hindawi.com)
  • Offering a choice of a urine test, hair drug test, saliva drug test or a combination of tests, our drug testing methods ensure the possibility for short-term and long-term drug abuse profiling. (randox.com)
  • Utilisation of different testing methods also ensures flexibility of drug abuse profiling with the ability to offer short-term drug abuse profiling via oral fluid and urine testing, long-term drug abuse profiling via hair testing or a combination of both. (randox.com)
  • Urine testing is the best developed and most commonly used monitoring technique in substance abuse treatment programs. (nih.gov)
  • It is important that the scheduled frequency of urine collection match the usual detection window for the primary drug. (nih.gov)
  • National Institute on Alcohol Abuse and Alcoholism - Conducts research on the impact of alcohol abuse, provides brochures and fact sheets. (orlandohealth.com)
  • Overview of substance abuse and alcoholism . (healthyplace.com)
  • An estimated 40 million adults in the United States are considered "heavy drinkers" of alcohol, with 10 million dependent on the substance, according to the National Institute on Alcohol Abuse and Alcoholism (NIAAA). (jaoa.org)
  • 5. Involvement in chronic behavior to obtain the substance, us the substance, or recover from its effects. (prezi.com)
  • The program will raise attorney awareness about the challenges of identifying the initial behavior which indicate abuse of alcohol, drugs and even prescription medication. (nacle.com)
  • The use of various substances to modify mood or behavior is generally regarded as normal and acceptable in our society. (healthyplace.com)
  • Williams RJ, Chang SY: A comprehensive and comparative review of adolescent substance abuse treatment outcome. (aerzteblatt.de)
  • This site can be of tremendous use to educators in that it can be a valuable asset for information into the world of substance abuse and how abusers can be spotted and then redirected. (hubpages.com)
  • Substance abusers require extensive patience, compassion, and sensitivity to treat and to heal. (positivearticles.com)
  • When the effects on the families of abusers and people close to those injured or killed by intoxicated drivers are considered, such abuse affects untold millions more. (healthyplace.com)
  • As related above, those whom psychiatrists and other mental health professionals would classify as "substance abusers" can't control their use of alcohol or other drugs. (healthyplace.com)
  • This gas chromatographic method allows the separation and quantitation by many volatile substances, especially ethanol, but is also useful in quantitation of other abused inhalants such as gasoline or glue (toluene). (healthy.net)
  • General Clinical Interviews, Standardized Specialty, Drug Detection and Personality. (routledge.com)
  • Standardized Alcohol and Other Drug (AOD) Specialty Assessment Instruments and Drug Detection Testing Introduction: Psychometric Fundamentals. (routledge.com)
  • Mental Health America - Advocacy organization addresses mental health and substance abuse, access to behavioral services through prevention, detection and diagnosis, education and research. (orlandohealth.com)
  • But when regular use of these substances begins to interfere with normal functioning, creating behavioral changes that would be undesirable to people from any cultural background, substance use has turned to substance abuse. (healthyplace.com)
  • Volatile substances include the most frequently abused drug - ethanol. (healthy.net)
  • Testing and detection using hair analysis for professional organisations in the management of drug misuse and addiction. (directoryhealthy.com)
  • Copy cialis - A however, some infants are slightly rated eyes) and hypotelorism (narrowly separated elevated on the child may become reversed, with pairment (ie, addiction or mental abuse) before embark- feedback and health needs of cialis copy children with primary herpes to morbidity in chil- ( , ml) will also dition in which the comes for everyone affected by or acquired infection, jaundice is infrequent. (wellchild.org)
  • These mental illnesses could be coupled with an addiction involving prescription drugs, alcohol, heroin, marijuana, or any other substance of abuse. (tapartnership.org)
  • In many cases, the mental illness might be the underlying cause of your substance abuse and addiction. (tapartnership.org)
  • Although clients would leave these centers having overcome their substance addiction, they eventually relapse after completing treatment. (tapartnership.org)
  • Although every state has its fair share of substance abuse and addiction issues, research studies show that North Dakota is close to the top in terms of alcohol abuse across the country. (tapartnership.org)
  • National Institute on Drug Abuse - Provides information on prevention and treatment of addiction, drug facts, updates about research in prevention and treatment, education, publications, podcast and newsletters. (orlandohealth.com)
  • The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. (frontiersin.org)
  • The prevalence of alcohol abuse among patients treated (or least diagnosed) in this setting is considered to be substantial. (frontiersin.org)
  • The ASSIST-linked brief intervention for hazardous and harmful substance use: a manual for use in primary care / prepared by R. HumeniukƯ [et al]. (who.int)
  • Parents with accurate and conclusive evidence of drug or alcohol use can take action appropriate to the severity of use, and since the odds of successful intervention or treatment decline the longer the abuse is allowed to continue, parents with an early awareness of use can be in a great position to help teens overcome some very tough situations and dependencies. (choosehelp.com)
  • This new manual offers a substantive update of the previous manual's 16 chapters, offering 7 additional chapters devoted to important new topics, such as pediatric primary care assessment and intervention, electronic tools, specific substances (e.g., cannabis, opioids, alcohol), and much more. (appi.org)
  • The book provides active learning experiences for graduate students in the helping professions and dispels much of the mystery of both diagnosis and substance abuse intervention. (routledge.com)
  • Faulds works on the development of surface-enhanced Raman spectroscopy (SERS) for analytical detection. (wikipedia.org)
  • As a service to our clients and friends (including those whose last names do not fall into this range), we would like to invite you to our annual MCLE workshop, which includes 2 hours on Ethics, 1 hour on Elimination of Bias, and 1 hour on Detection/Prevention of Substance Abuse. (mofo.com)
  • This event presents an ideal opportunity to earn CLE credits before the compliance deadline, including Ethics and Detection/Prevention of Substance Abuse credits. (fenwick.com)
  • Ohio Twenty-four hours are required every 2 years including one hour for ethics, one hour for professionalism and .5 hour for substance abuse. (benchmarkinstitute.org)
  • Florida Over a 3 year period, each member must complete 30 hours, 5 of which are in the area of ethics, professionalism, substance abuse, or mental illness awareness. (benchmarkinstitute.org)
  • including 3 hours ethics or office management or substance abuse per cycle. (benchmarkinstitute.org)
  • This site addresses the classifications, the pharmaceutical as well as common street names of the substances, effects, delivery, overdose effects and consequences, signs and symptoms and common means of acquisition. (hubpages.com)
  • Even though you might be using the addictive substance to manage your mental health symptoms, eventually, you will find that this does not work in the long run. (tapartnership.org)
  • Some are characteristic symptoms of particular substances. (positivearticles.com)
  • Those who are considered to be dependent on a substance suffer all the symptoms of drug abuse, with the addition that they have developed a physical tolerance for it, so that increased amounts are necessary for the desired effects. (healthyplace.com)
  • Available at http://www.who.int/substance_abuse/publications/global_alcohol_report/gsr_2018/en/ . (medscape.com)
  • I thought you might be interested in this item at http://www.worldcat.org/oclc/1013462261 Title: Doping, performance-enhancing drugs, and hormones in sport : mechanisms of action and methods of detection Author: Anthony C Hackney Publisher: Amsterdam, Netherlands : Elsevier, 2018. (worldcat.org)
  • Drug tests can detect increases in the detection of substance abuse and their metabolites form. (blogtopsites.com)
  • This invention relates generally to the field of the detection of drugs and drug metabolites in biological samples. (google.com)
  • The Alcohol, Smoking and Substance involvement Screening Test (ASSIST): manual for use in primary care / prepared by R. HumeniukƯ [et al]. (who.int)
  • Ault, A. Proven Screening Tool for Alcohol Abuse Underutilized. (medscape.com)
  • The meropenem-MIC range used in the BDPCPO panel includes the EUCAST screening breakpoint for the detection of carbapenemase producers. (bioportfolio.com)
  • Confirm BioSciences works with many homeless shelters, faith centers and rescue missions around the country to help create a drug screening program that will help provide a substance abuse free environment for these shelters. (confirmbiosciences.com)
  • Subjects screening positive for possible alcohol abuse were given treatment referrals. (jaoa.org)
  • Students and practitioners alike will benefit from this comprehensive volume on the assessment and diagnosis of substance abuse. (routledge.com)
  • This site provides pictures and how the various substances looked and are disguised for sale or resale. (hubpages.com)
  • assay for detection of carbapenemase activity in the BDPCPO panel displays high sensitivity for carbapenemase detection while its specificity is modest. (bioportfolio.com)
  • Clinical Validation of the Molecular-Based GenePOC Carba Assay for the Detection and Differentiation of Carbapenemase Genes in Rectal Swab Samples. (bioportfolio.com)
  • Additionally, we can provide a wide range of assay formats including single nucleotide polymorphisms (SNP) genotyping, pathogen detection and mutation detection. (randox.com)
  • The invention relates to an assay system for the improved detection of analytes, and the ability to distinguish them from cross-reacting substances. (google.com)
  • Samples giving a positive reaction in a direct assay test are treated with a neutralizing antibody that inhibits reactivity of the true analyte, but not the interfering substance. (google.com)
  • The confirmatory assay easily distinguishes the true analyte and reduces the rate of false positives, even when the interfering substance is unknown and present at high concentration. (google.com)
  • If you suspect someone you know is abusing drugs and has become dependent on them, it is important that you not waste any time intervening. (icsworld.com)
  • Wilson CR, Sherritt L, Gates E, Knight JR: Are clinical impressions of adolescent substance use accurate? (aerzteblatt.de)
  • We have retrospectively analyzed the variations in the clinical profile of patients with a positive consumption of alcohol and/or drugs of abuse that have been confirmed and treated in the Emergency Department of a Virgen de La Arrixaca University Hospital in Murcia (Spain) after a period of 10 years. (hindawi.com)
  • From parents to the rest of the community, all must be involved in these aspects of substance abuse in adolescents. (hubpages.com)
  • Prescription drug abuse among adolescents is gaining the attention of the country, but most specifically parents, educators, and community officials. (hubpages.com)
  • This site gives the tools for parents, educators, community leaders, law enforcements officials, and pharmacies in the prevention of prescription drug abuse in adolescents. (hubpages.com)
  • This site addresses the risk factors and comparable protective factors of substance abuse by adolescents. (hubpages.com)
  • The involvement of all of us from parents to teachers to the entire community in doing what it takes in the detection and prevention of substance abuse in adolescents. (hubpages.com)
  • We offer a wide range of quality products designed to test for illegal substances quickly and efficiently, ensuring minimal disruption in your workplace. (randox.com)
  • In some groups, even the recreational use of alcohol is frowned upon, whereas in other groups the use of various legal or illegal substances for mood-altering effects has become widely accepted. (healthyplace.com)
  • Scientists of the Max Planck Institute of Psychiatry in Munich have now discovered biomarkers, which allow detection of at risk patients before birth and early treatment. (mpg.de)
  • Overall, these results indicate high rates of smoking in MMT patients, confirm within a drug abusing population prior findings of racial differences in smoking habits, and suggest that MMT patients are interested in quitting and in using nicotine replacement products. (nih.gov)
  • Illustrating the importance of early detection of drug abuse, those with substance abuse issues should contact a detox center like Harbor Village. (prweb.com)
  • This site addresses the early detection, role of families, and prevention. (hubpages.com)
  • A study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013, suggests that early detection of PML may help improve survival and disability levels. (healthcanal.com)
  • These results suggest that the consequences of PML infection can be mitigated by early detection of the disease," said Dong-Si. (healthcanal.com)
  • 1 Therefore, it is vital for early and accurate detection. (randox.com)
  • Another big positive is early detection of a substance abuse problem. (choosehelp.com)
  • Discipline and substance abuse is suspected, posteroanterior as an important cally, to promote early detection. (wellchild.org)
  • 100 Schools Project Targets Early Detection of Mental Health and Substance Abuse Issues Among Teens, JewishBoard.org, September 2016. (wikipedia.org)
  • Liedberg is also interacting strongly the bioanalytical industry in Sweden, and he was involved the early development of the optical detection system (surface plasmon resonance based) used in today's Biacore instrumentation for biospecific interaction analysis (currently sold by GE-Healthcare). (ntu.edu.sg)
  • The scientific team of Elisabeth Binder therefore aimed at discovering biomarkers for detection of at risk patients before birth to allow early treatment or prevention. (mpg.de)
  • Wong WK , Moore M , Cooper G , Wagner M . What's strange about recent events (WSARE): an algorithm for the early detection of disease outbreaks. (cdc.gov)
  • The annual cost of alcohol abuse is nearly $86 billion for treatment and indirect losses such as reduced worker productivity, early death and property damage resulting from alcohol-related accidents and crime each year. (healthyplace.com)
  • Dangers Of Marijuana Abuse Of Synthetic on Feb 24, 2011 in Drug - Alcohol By: Nate RodnayJWH-018 is a chemical anti-pain, often described as an analgesic naphthoylindole family, which acts on cannabinoid receptors in the brain. (blogtopsites.com)
  • The training specialty of teaching explosive detection dogs and their handlers requires additional knowledge about explosives and law enforcement procedures. (study.com)
  • CHASE, LLC provides substance use/abuse testing programs to a diverse group of industries that are either under federal mandate or simply choose to maintain a drug free workplace. (chasesafety.com)
  • The Substance Abuse and Mental Health Services Administration (SAMHSA) has a number of documents about drug testing available in the Workplace Resources section of its Web site, www.samhsa.gov . (nih.gov)
  • The technology allows simultaneous detection of multiple analytes from a single sample for efficient and cost-effective testing. (randox.com)
  • In this study, we identified specific carbapenemase-producing isolates applying an easy and rapid protocol for the detection of mature KPC-2 β-lactamase by MALDI-TOF MS from colony and positive blood. (bioportfolio.com)
  • In adsorption type confirmatory assays, the neutralizing antibody is provided in an amount sufficient to adsorb the analyte but not all of the interfering substance. (google.com)
  • In December 2020, FMCSA hosted a series of question and answer webinar sessions for Clearinghouse users, including two sessions for medical review officers (MROs) and substance abuse professionals (SAPs). (chasesafety.com)
  • We assess several methods to determine carbapenemase production of Enterobacterales in culture and discuss the value of the novel automated BD Phoenix CPO Detect (BDPCPO) panel for the detection and classification of carbapenemases. (bioportfolio.com)
  • Achiral and chiral semi-micro column high-performance liquid chromatographic methods with fluorescence detection to determine methamphetamine and amphetamine in human hair are described. (biomedsearch.com)
  • 5). The limits of detection at a signal-to-noise ratio of 3 obtained by both the methods were in the range of 1.0-4.7 fmol/5 microL injection with the achiral method being more sensitive. (biomedsearch.com)
  • This site addresses the many types of substances that teens use and the methods they administer them. (hubpages.com)
  • With different drug testing methods having different windows of detection, we offer advice on which methods to utilise depending upon your company's drug testing requirements, ensuring the best method or combination of methods is chosen to ensure all your testing needs are fulfilled. (randox.com)
  • This appendix describes procedures for implementing this service and other methods for detecting clients' substance use. (nih.gov)
  • Bomb detection dog trainers use conditioning methods and performance rewards to teach dogs to identify different types of explosives and respond at all times to human commands. (study.com)
  • We reviewed non-HIV outbreak detection literature and methods employed by disease and syndromic surveillance programs at CDC and in several state and local health departments. (cdc.gov)
  • Chen D , Cunningham J , Moore K , Tian J . Spatial and temporal aberration detection methods for disease outbreaks in syndromic surveillance systems. (cdc.gov)
  • Comparing aberration detection methods with simulated data. (cdc.gov)
  • According to the National Institute of Mental Health, nearly 17 percent of the U.S. population 18 years old and over will fulfill criteria for alcohol or drug or other substance abuse during their lifetimes. (healthyplace.com)
  • Substance Abuse and Mental Health Services Administration. (medscape.com)
  • Professor Busch's work has been funded by the National Institute of Mental Health, the National Institute of Drug Abuse and the Robert Wood Johnson Foundation. (yale.edu)
  • Boulder County, Colo. - A group of Boulder County organizations has released the Mental Health Community Assessment on the state of mental health and substance use treatment services in Boulder County. (bouldercounty.org)
  • The Community of Hope study confirms much of what we know," said Kelly Phillips-Henry, CEO of Mental Health Partners, Boulder County's largest provider of mental health and substance use treatment. (bouldercounty.org)
  • However, of those six hours, Illinois attorneys must complete one hour of diversity/inclusion PR CLE and one hour of mental health/substance abuse PR CLE. (nacle.com)
  • This is a listing of Mental Health and Substance Abuse CLE Courses for Illinois. (nacle.com)
  • The statistics dealing with lawyers and law students regarding Mental Illness and Substance Abuse are eye-opening. (nacle.com)
  • The incidence of cases in which capacity is an issue has grown substantially in the past few years because of the aging demographic and the increasing number of cases involving serious mental illness, substance and/or alcohol abuse, or other related mental health concerns. (nacle.com)
  • But which are the mental health problems that are most commonly associated with drug and alcohol abuse in North Dakota? (tapartnership.org)
  • Many factors can contribute to homelessness, some of which include poverty, job loss, substance abuse, mental illness and domestic violence. (confirmbiosciences.com)
  • Substance abuse is one of the most powerful addictive behaviors that people fall victim to. (icsworld.com)
  • Because of the profound distress and impairment in the lives of those affected by PTSD, many people abuse drugs or alcohol to cope. (recovery.org)
  • As psychiatrists define it, a person has a substance abuse problem when they continue to use a substance--some form of drug, medication or alcohol -- despite the recurring social, occupational, psychological or physical problems such use causes. (healthyplace.com)
  • While alcohol is considered by psychiatrists to be a "drug," for the purposes of this pamphlet its abuse is being discussed separately from that of other drugs. (healthyplace.com)
  • Unfortunately, while abuse instigators are commonly known, treatment is often misunderstood. (positivearticles.com)
  • Would you like to learn how to effectively communicate with youth about the harms and consequences of alcohol and other drugs of abuse? (familysupportalliance.org)
  • Special chapters are devoted to the management of youth with SUDs in the juvenile justice system and the consequences, for the child, of maternal substance use during pregnancy. (appi.org)
  • Peterson K. Biomarkers for alcohol use and abuse. (medscape.com)
  • According to some studies, between patients treated 4 and 40% may show signs of consuming some kind of toxic substance excluding tobacco [ 1 - 4 ]. (hindawi.com)
  • The Old Style toxic substance removal hair shampoo is best used with the home-based medicine testing set from Examination Clear. (phenomenica.com)
  • Performance Evaluation of MALDI-TOF MS MBT STAR-BL Versus In-House Carba NP Testing for the Rapid Detection of Carbapenemase Activity in Escherichia coli and Klebsiella pneumoniae Strains. (bioportfolio.com)
  • Rapid detection of increases in HIV transmission enables targeted outbreak response efforts to reduce the number of new infections. (cdc.gov)