Styrene: A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.Styrenes: Derivatives and polymers of styrene. They are used in the manufacturing of synthetic rubber, plastics, and resins. Some of the polymers form the skeletal structures for ion exchange resin beads.Mandelic Acids: Analogs or derivatives of mandelic acid (alpha-hydroxybenzeneacetic acid).Plastics: Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Epoxy Compounds: Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS.GlyoxylatesAir Pollutants, Occupational: Air pollutants found in the work area. They are usually produced by the specific nature of the occupation.Polystyrenes: Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.Occupational Medicine: Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.Ethylene Glycols: An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.Chemical Industry: The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)Phenylacetates: Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.Occupational Exposure: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.Ships: Large vessels propelled by power or sail used for transportation on rivers, seas, oceans, or other navigable waters. Boats are smaller vessels propelled by oars, paddles, sail, or power; they may or may not have a deck.Pseudomonas putida: A species of gram-negative, aerobic bacteria isolated from soil and water as well as clinical specimens. Occasionally it is an opportunistic pathogen.Biodegradation, Environmental: Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.Oxygenases: Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)FMN Reductase: An enzyme that utilizes NADH or NADPH to reduce FLAVINS. It is involved in a number of biological processes that require reduced flavin for their functions such as bacterial bioluminescence. Formerly listed as EC and EC It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Poly A: A group of adenine ribonucleotides in which the phosphate residues of each adenine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Intellectual Property: Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)Access to Information: Individual's rights to obtain and use information collected or generated by others.Butylene Glycols: 4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.Facility Regulation and Control: Formal voluntary or governmental procedures and standards required of hospitals and health or other facilities to improve operating efficiency, and for the protection of the consumer.United States Food and Drug Administration: An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)Societies, Pharmaceutical: Societies whose membership is limited to pharmacists.WashingtonPublic Opinion: The attitude of a significant portion of a population toward any given proposition, based upon a measurable amount of factual evidence, and involving some degree of reflection, analysis, and reasoning.Politics: Activities concerned with governmental policies, functions, etc.Policy Making: The decision process by which individuals, groups or institutions establish policies pertaining to plans, programs or procedures.Gift Giving: The bestowing of tangible or intangible benefits, voluntarily and usually without expectation of anything in return. However, gift giving may be motivated by feelings of ALTRUISM or gratitude, by a sense of obligation, or by the hope of receiving something in return.Gambling: An activity distinguished primarily by an element of risk in trying to obtain a desired goal, e.g., playing a game of chance for money.Social Security: Government sponsored social insurance programs.Insurance, Disability: Insurance designed to compensate persons who lose wages because of illness or injury; insurance providing periodic payments that partially replace lost wages, salary, or other income when the insured is unable to work because of illness, injury, or disease. Individual and group disability insurance are two types of such coverage. (From Facts on File Dictionary of Health Care Management, 1988, p207)Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Ethylenes: Derivatives of ethylene, a simple organic gas of biological origin with many industrial and biological use.Glycols: A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Formularies as Topic: Works about lists of drugs or collections of recipes, formulas, and prescriptions for the compounding of medicinal preparations. Formularies differ from PHARMACOPOEIAS in that they are less complete, lacking full descriptions of the drugs, their formulations, analytic composition, chemical properties, etc. In hospitals, formularies list all drugs commonly stocked in the hospital pharmacy.Economics, Pharmaceutical: Economic aspects of the fields of pharmacy and pharmacology as they apply to the development and study of medical economics in rational drug therapy and the impact of pharmaceuticals on the cost of medical care. Pharmaceutical economics also includes the economic considerations of the pharmaceutical care delivery system and in drug prescribing, particularly of cost-benefit values. (From J Res Pharm Econ 1989;1(1); PharmacoEcon 1992;1(1))Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Academies and Institutes: Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.Security Measures: Regulations to assure protection of property and equipment.Acrylonitrile: A highly poisonous compound used widely in the manufacture of plastics, adhesives and synthetic rubber.Polyanhydrides: Anhydride polymers with a repeating structure of RC(=O)OC(=O)R. They readily hydrolyze in water making them useful for DELAYED-ACTION PREPARATIONS.Rubber: A high-molecular-weight polymeric elastomer derived from the milk juice (LATEX) of HEVEA brasiliensis and other trees and plants. It is a substance that can be stretched at room temperature to at least twice its original length and after releasing the stress, retract rapidly, and recover its original dimensions fully.Silicon Compounds: Inorganic compounds that contain silicon as an integral part of the molecule.Butadienes: Four carbon unsaturated hydrocarbons containing two double bonds.Nanopores: Small holes of nanometer dimensions in a membrane, that can be used as single molecule detectors. The pores can be biological or synthetic.Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].

Metabolism of the antimalarial endoperoxide Ro 42-1611 (arteflene) in the rat: evidence for endoperoxide bioactivation. (1/332)

Ro 42-1611 (arteflene) is a synthetic endoperoxide antimalarial. The antimalarial activity of endoperoxides is attributed to iron(II)-mediated generation of carbon-centered radicals. An alpha, beta-unsaturated ketone (enone; 4-[2',4' bis(trifluoromethyl)phenyl]-3-buten-2-one), obtained from arteflene by reaction with iron(II), was identified previously as the stable product of a reaction that, by inference, also yields a cyclohexyl radical. The activation of arteflene in vivo has been characterized with particular reference to enone formation. [14C]Arteflene (35 micromol/kg) was given i.v. to anesthetized and cannulated male rats: 42.2 +/- 7.0% (mean +/- S.D., n = 7) of the radiolabel was recovered in bile over 5 h. In the majority of rats, the principal biliary metabolites were 8-hydroxyarteflene glucuronide (14.2 +/- 3. 9% dose, 0-3 h) and the cis and trans isomers of the enone (13.5 +/- 4.6% dose, 0-3 h). In conscious rats, 15.3 +/- 1.6% (mean +/- S.D., n = 8) of the radiolabel was recovered in urine over 24 h. The principal urinary metabolite appeared to be a glycine conjugate of a derivative of the enone. Biliary excretion of the glucuronide, but not of the enones, was inhibited by ketoconazole. 8-Hydroxyarteflene was formed extensively by rat and human liver microsomes but no enone was found. Bioactivation is a major pathway of arteflene's metabolism in the rat. Although the mechanism of in vivo bioactivation is unclear, the reaction is not catalyzed by microsomal cytochrome P-450 enzymes.  (+info)

Characterization of inhaled alpha-methylstyrene vapor toxicity for B6C3F1 mice and F344 rats. (2/332)

alpha-Methylstyrene (AMS) is a chemical intermediate used in the synthesis of specialty polymers and copolymers. Inhalation studies of AMS were conducted because of the lack of toxicity data and the structural similarity of AMS to styrene, a toxic and potentially carcinogenic chemical. Male and female B6C3F1 mice were exposed to 0, 600, 800, or 1000 ppm AMS 6 h/day, 5 days/week, for 12 days. After 1 exposure, 21% (5/24) of female mice were found dead in the 1000-ppm group, 56% (10/18) in the 800-ppm group, and 6% (1/18) in the 600-ppm concentration group. After 12 exposures, relative liver weights were significantly increased and relative spleen weights were significantly decreased in both male and female mice at all concentrations. No microscopic treatment-related lesions were observed. A decrease in hepatic glutathione (GSH) was associated with AMS exposure for 1 and 5 days. Male and female F344 rats were exposed to 0, 600 or 1000 ppm AMS for 12 days. No mortality or sedation occurred in AMS-exposed rats. Relative liver weights were significantly increased in both males and females after 12 exposures to 600 or 1000 ppm. An increased hyaline droplet accumulation was detected in male rats in both concentration groups; no significant microscopic lesions were observed in other tissues examined. Exposure of male and female F344 rats and male NBR rats to 0, 125, 250 or 500 ppm AMS, 6 h/day for 9 days resulted in increased accumulation of hyaline droplets in the renal tubules of male F344 rats in the 250 and 500 ppm concentration groups. Although AMS and styrene are structurally very similar, AMS was considerably less toxic for mice and more toxic for male rats than styrene.  (+info)

Influence of anions and cations on the dipole potential of phosphatidylcholine vesicles: a basis for the Hofmeister effect. (3/332)

Anions and cations have long been recognized to be capable of modifying the functioning of various membrane-related physiological processes. Here, a fluorescent ratio method using the styrylpyridinium dyes, RH421 and di-8-ANEPPS, was applied to determine the effect of a range of anions and cations on the intramembrane dipole potential of dimyristoylphosphatidylcholine vesicles. It was found that certain anions cause a decrease in the dipole potential. This could be explained by binding within the membrane, in support of a hypothesis originally put forward by A. L. Hodgkin and P. Horowicz [1960, J. Physiol. (Lond.) 153:404-412.] The effectiveness of the anions in reducing the dipole potential was found to be ClO4- > SCN- > I- > NO3- > Br- > Cl- > F- > SO42-. This order could be modeled by a partitioning of ions between the membrane and the aqueous phase, which is controlled predominantly by the Gibbs free energy of hydration. Cations were also found to be capable of reducing the dipole potential, although much less efficiently than can anions. The effects of the cations was found to be trivalent > divalent > monovalent. The cation effects were attributed to binding to a specific polar site on the surface of the membrane. The results presented provide a molecular basis for the interpretation of the Hofmeister effect of lyotropic anions on ion transport proteins.  (+info)

Quantitative analysis of styrene monomer in polystyrene and foods including some preliminary studies of the uptake and pharmacodynamics of the monomer in rats. (4/332)

A variety of food containers, drinking cups and cutlery, fabricated from polystyrene (PS) or polystyrene-related plastic, were analyzed for their styrene monomer content. Samples of yogurt, packaged in PS cups, were similarly analyzed and the leaching of styrene monomer from PS containers by some food simulants was also determined. Blood level studies with rats, dosed with styrene monomer by various routes, illustrated uptake phenomena that were dependent on the dose and route of administration and were also affected by the vehicle used to convey the styrene monomer.  (+info)

Hepatic and extrahepatic metabolism of 14C-styrene oxide. (5/332)

With 8-(14)C-styrene oxide as substrate, specific glutathione S-transferase and epoxide hydrase activities were determined in subcellular fractions of liver, lungs, kidney, and intestinal mucosa from rabbit, rat, and guinea pig. Liver had the highest enzyme activities in each species. Rat and guinea pig had higher glutathione S-transferase activity in both liver and kidney than rabbit. Rat testis also had appreciable glutathione S-transferase activity. The perinatal development of epoxide hydrase and glutathione S-transferase was followed in liver and several extrahepatic tissues of fetal and neonatal guinea pigs and rabbits. The rates at which enzyme activities reached adult levels in the extrahepatic tissues differed from the liver in both species. Epoxide hydrase and glutathione S-transferases developed at different rates in each organ, demonstrating that the relative importance of these two detoxifying pathways for styrene oxide may shift before and after birth. The effects of pretreating male and female rats with phenobarbital (PB), 1,2,3,4-dibenzanthracene (DBA), pregnenolone-16alpha-carbonitrile (PCN), or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hepatic and extrahepatic epoxide hydrase and glutathione S-transferase activities toward styrene oxide were determined. PB increased both enzyme activities in liver of both sexes. PCN induced only glutathione S-transferase activity in female liver. Extrahepatic epoxide hydrase and glutathione S-transferase activities were unaffected except that TCDD doubled female renal epoxide hydrase activity and PB increased intestinal epoxide hydrase activity in both sexes. Styrene oxide biotransformation was studied in isolated, perfused rat liver and rabbit lung preparations. Conjugation with glutathione was a major metabolic pathway although significant amounts of diol were also formed in each instance. In rat liver, 27-40% of the administered styrene oxide was excreted via the bile mainly as S-(1-phenyl-2-hydroxyethyl)glutathione.  (+info)

Clinical studies of styrene workers: initial findings. (6/332)

Styrene monomer is a high volume chemical used chiefly in production of polystyrene. A clinical survey of 493 production workers was undertaken at the oldest and largest monomer production, polymerization, and extrusion facility in the U.S. Relative exposure durations and levels were obtained from occupational histories. Significant differences between the high and low exposure groups were found with regard to history of acute prenarcotic symptoms, acute lower respiratory symptoms, prevalence of FEV 1/FV less than 75 per cent, and elevated GCTP. Other liver function tests, chest x-ray, FVC less than 80 per cent, and hematological parameters showed no distinct pattern. A concomitant mortality study has been mounted and is in progress.  (+info)

Hofmeister effects of anions on the kinetics of partial reactions of the Na+,K+-ATPase. (7/332)

The effects of lyotropic anions, particularly perchlorate, on the kinetics of partial reactions of the Na+,K+-ATPase from pig kidney were investigated by two different kinetic techniques: stopped flow in combination with the fluorescent label RH421 and a stationary electrical relaxation technique. It was found that 130 mM NaClO4 caused an increase in the Kd values of both the high- and low-affinity ATP-binding sites, from values of 7.0 (+/- 0.6) microM and 143 (+/- 17) microM in 130 mM NaCl solution to values of 42 (+/- 3) microM and 660 (+/- 100) microM in 130 mM NaClO4 (pH 7.4, 24 degrees C). The half-saturating concentration of the Na+-binding sites on the E1 conformation was found to decrease from 8-10 mM in NaCl to 2.5-3.5 mM in NaClO4 solution. The rate of equilibration of the reaction, E1P(Na+)3 left arrow over right arrow E2P + 3Na+, decreased from 393 (+/- 51) s-1 in NaCl solution to 114 (+/- 15) s-1 in NaClO4. This decrease is attributed predominantly to an inhibition of the E1P(Na+)3 --> E2P(Na+)3 transition. The effects can be explained in terms of electrostatic interactions due to perchlorate binding within the membrane and/or protein matrix of the Na+,K+-ATPase membrane fragments and alteration of the local electric field strength experienced by the protein. The kinetic results obtained support the conclusion that the conformational transition E1P(Na+)3 --> E2P(Na+)3 is a major charge translocating step of the pump cycle.  (+info)

Effect of gramicidin A on the dipole potential of phospholipid membranes. (8/332)

The effect of channel-forming peptide gramicidin A on the dipole potential of phospholipid monolayers and bilayers has been studied. Surface pressure and surface potential isotherms of monolayers have been measured with a Langmuir trough equipped with a Wilhelmy balance and a surface potential meter (Kelvin probe). Gramicidin has been shown to shift pressure-area isotherms of phospholipids and to reduce their monolayer surface potentials. Both effects increase with the increase in gramicidin concentration and depend on the kind of phosphatidylcholine used. Application of the dual-wavelength ratiometric fluorescence method using the potential-sensitive dye RH421 has revealed that the addition of gramicidin A to dipalmitoylphosphatidylcholine liposomes leads to a decrease in the fluorescence ratio of RH421. This is similar to the effect of phloretin, which is known to decrease the dipole potential. The comparison of the concentration dependences of the fluorescence ratio for gramicidin and phloretin shows that gramicidin is as potent as phloretin in modifying the membrane dipole potential.  (+info)

  • Conti B, Maltoni C, Perino G, Ciliberti A (1988) Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats, and paramethylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice. (
  • Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide. (
  • Reviewed: new music from Poly Styrene, Gary Lucas & Gods and Monsters, and Daniel Knox. (
  • Powered by a pumping dance groove, Poly Styrene sings , "Threw the credit card away/Got out of the red and into the black/I'm looking to the future and I'm not looking back," in a pointed but good-natured essay on consumerism and pop culture. (
  • But given that the rocker is singer Poly Styrene, the post is appropriate. (
  • Where does the name "Poly Styrene" come from? (
  • A playlist of late X-Ray Spex singer Poly Styrene 's favourite tracks has been unveiled to mark what would have been her 54th birthday today (July 3) - click here to launch it . (
  • (
  • Styrene/maleic acid copolymers (SMA) have recently attracted great interest for in vitro studies of membrane proteins, as they self-insert into and fragment biological membranes to form polymer-bounded nanodiscs that provide a native-like lipid-bilayer environment. (
  • Styrene-acrylonitrile trimer (SAN Trimer), a mixture of six isomers (four isomers of 4-cyano-1,2,3,4-tetrahydro-alpha-methyl-1-naphthaleneacetonitrile [THAN] and two isomers of 4-cyano-1,2,3,4-tetrahydro-1-naphthaleneproprionitrile [THNP]), is a by-product of a specific production process of styrene-acrylonitrile polymer. (
  • Disclosed are a styrene-based resin composite material in which a layer composed mainly of a curable phosphazene compound is formed on the surface of a molding material of a styrene-based polymer having a mainly syndiotactic configuration or a composition thereof, and also a magnetic recording medium. (
  • 1. A magnetic recording medium which comprises a support of a styrene-based polymer having a syndiotactic configuration or a composition thereof, a magnetic layer containing a curable phosphazene compound as a binder formed on the support and a lubricating layer containing a curable phosphazene compound formed on the support at the opposite side of the magnetic layer. (
  • SBR latex is a kind of high-polymer dispersion emulsion polymerized by butadiene, and styrene, etc. through advanced techniques. (
  • The polystyrene-based terpyridine polymer was prepared from 4-chloromethyl styrene [ 9 ]. (
  • Molecular model of the aromatic alkene styrene (C8.H8), a colourless oily liquid which is used as a precursor to the polymer and plastic polystyrene. (
  • The recently published report titled Global Styrene-based TPE Industry 2018 Market Research Report is an in depth study providing complete analysis of the industry for the period 2018 - 2025. (
  • The Global Styrene-based TPE Industry Report 2018 is an in depth study analyzing the current state of the Global Styrene-based TPE market. (
  • The global market for styrene manufacturing should grow from $75.4 billion in 2018 to $86.8 billion by 2023, at a compound annual growth rate (CAGR) of 2.8% for the period of 2018-2023. (
  • The global acrylonitrile styrene acrylate (ASA) market is estimated to grow at a CAGR of REDACTED% during the forecast period.It is expected that the market will generate a revenue of $REDACTED million by 2023 ascompared to $REDACTED million in 2018. (
  • It is important to know for present and former workers exposed to styrene that they are unlikely to have become ill by doing their job, if they have developed cancer of the oesophagus, pancreas, lungs, kidneys, bladder or a wide range of other types of cancer. (
  • Prolonged latencies of peripheral and cortical SEPs were found in workers exposed to styrene. (
  • but now a registry study of more than 72,000 employees from more than 400 companies that have been exposed to styrene during production of glassfibre reinforced plastics, has not found an increased incidence of a wide range of cancer types. (
  • Employees in the glass fibre reinforced plastics who have worked with the chemical styrene do not have - as previously feared - an increased incidence of cancer of the oesophagus, pancreas, lungs, kidneys, bladder or a wide range of other types of cancer. (
  • Henrik A. Kolstad emphasises that the sins of the past are the focal point here, and that the working environment has changed significantly since then, so that work with styrene in the reinforced plastics industry in Denmark today takes place in closed spaces with strict exhaust ventilation requirements. (
  • Styrene isn't known to leach out of hard plastics, but some evidence suggests that it can leach out of foam food containers and cups when food or drinks are hot - not when they're cold. (
  • Our recent blog on this subject urged people to opt for paper products, or non-styrene plastics that are washable and reusable. (
  • The Department of Health and Human Services (DHHS), National Toxicology Program (NTP) listed styrene as "reasonably anticipated to be a human carcinogen" in the Report on Carcinogens, Twelfth Edition, released on June 10, 2011. (
  • The International Agency for Research on Cancer (IARC) has determined that styrene is a possible human carcinogen. (
  • Styrene was listed as reasonably anticipated to be a carcinogen in the Thirteenth Report on Carcinogens published by the National Toxicology Program. (
  • Just this week , the National Research Council (NRC) signed off on the National Toxicology Program's decision to list styrene as "reasonably anticipated to be a human carcinogen" in its latest report on carcinogens. (
  • The styrene industry has fought the designation as a "reasonably anticipated human carcinogen" and good government science for years. (
  • A new report from the National Research Council has upheld the listing of styrene as "reasonably anticipated to be a human carcinogen" in the National Toxicology Program's 12th Report on Carcinogens (RoC). (
  • In its peer review of the 12th RoC, the committee examined the primary literature cited in the document as well as other research published before June 10, 2011, and found that the RoC identified the most important studies and described the limitations and strengths of each, and that the arguments supported listing styrene as reasonably anticipated to be a human carcinogen. (
  • It found that "compelling evidence" exists in human, animal, and mechanistic studies to support listing styrene, at a minimum, as reasonably anticipated to be a human carcinogen. (
  • The committee noted, however, that there was ambiguity with respect to weighing the mechanistic evidence when applying the listing criteria, and that a strong argument could be made to support the listing of styrene as a known human carcinogen if data derived from the study of human tissues or cells alone were considered sufficient. (
  • Plastruct Styrene Structural Shapes are precision-extruded in white styrene plastic. (
  • The Midwest White Styrene Sheet is a lightweight surface which is easy to bend and is compatible with plastic adhesives and most paints, including Humbrol enamel paints. (
  • Rated 4 out of 5 by Snake from 2mm white styrene sheet It is as it says white styrene sheet, A4 size. (
  • This report presents a strategic analysis of the styrene market in the Balkan countries and a forecast for its development in the medium term. (
  • The purpose of the report is to describe the state of the styrene market in the Balkan countries, to present actual and retrospective information about the volumes, dynamics, structure and characteristics of production, imports, exports and consumption and to build a forecast for the market in the next five years. (
  • According to recent analysis from Transparency Market Research, the styrene butadiene latex market is forecast to experience a compound annual growth rate of 3.3 percent through 2023. (
  • Conner MK, Alarie Y, Dombroske RL (1980) Sister chromatid exchange in murine alveolar macrophages, bone marrow, and regenerating liver cells induced by styrene inhalation. (
  • Pittsburgh, PA - NOVA Chemicals Corporation (NYSE, TSX: NCX ) today announced that it has secured exclusive rights to the styrene production from Sterling Chemicals Inc. s Texas City, Texas, manufacturing facility on behalf of its pending joint venture with INEOS. (
  • Check out our Hazardous 100+ list, to see where styrene falls and other chemicals to avoid. (
  • Some of the works consist of only one word - great , mud , trust - and others of short combinations or phrases, such as Indeed I do , She Sure Knew Her Devotionals , Your Polyester People , That Housing Tract is Only Texture , and, of course, They Called Her Styrene . (
  • Targeted primarily toward the marine and bathroom/spa market, styrene-free H164 polyester resin from AOC LLC (Collierville, TN, US) is a medium-reactive, thixotropic resin designed for the appli- cations most vulnerable in the current regulatory climate: hand lay-up or spray-up laminating processes. (
  • ATSDR's discussion of this effect is consistent with NTP's Expert Panel report on the reproductive and developmental toxicity of styrene. (
  • ICIS, a trusted provider of global petrochemical market pricing information, has expanded its suite of margin reports by launching a weekly report on the US styrene market. (
  • The ICIS Styrene US Margin report provides crucial information about various market factors, including feedstock prices and business cash costs, giving companies a better understanding of market dynamics. (
  • The volatile nature of the US styrene market underlines the benefits of a weekly report tracking variable costs and margins. (
  • This is the most detailed and comprehensive report about the styrene market in the Balkan countries currently available! (
  • It provides complete overview of Global Styrene-based TPE market considering all the major industry trends, market dynamics and competitive scenario. (
  • The study on Global Styrene-based TPE market provides analysis of China market covering the industry trends, recent developments in the market and competitive landscape. (
  • Research study on Global Styrene-based TPE market also discusses the opportunity areas for investors. (
  • Turnarounds understood to be underway for at least four European plants in September and October were lowering styrene supply, as they offered limited volumes on the spot market. (
  • NIOSHTIC-2 search results on styrene -NIOSHTIC-2 is a searchable database of worker safety and health publications, documents, grant reports, and journal articles supported in whole or in part by NIOSH. (
  • So far all styrene monooxygenases perform enantioselective epoxidations of styrene and chemically analogous compounds, which makes them interesting for biotechnological applications. (
  • The statement that children would have similar effects as adults was retained because there is no evidence for styrene or similar compounds that this would not be true. (
  • Dr. Leavens has authored and coauthored 12 articles and 20 abstracts in peer-reviewed journals on physiology and pharmacokinetics, including articles on the interaction of butadiene and styrene in rats. (
  • delta-Aminolevulinate dehydratase (ALA-D:porphobilinogen synthase, 5-aminolevulinate hydro-lyase, EC activity was depressed markedly in red cells of rats exposed to 0.21 g/m3 styrene, a chemical widely used in commercial products. (
  • Disposition of styrene-acrylonitrile (SAN) trimer in female rats: Single dose intravenous and gavage studies. (
  • The ICIS Styrene US Margin report provides an indication of where margins are heading, and can guide the business decisions of buyers, producers and traders of styrene and its derivatives. (