Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Stroke Volume
Cardiac Output
Hemodynamics
Brain Ischemia
Cerebrovascular Disorders
Fluid Therapy
Cardiography, Impedance
A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.
Thermodilution
Ventricular Function, Left
Vascular Resistance
Cardiac Volume
Hypovolemia
Prospective Studies
Magnetic Resonance Imaging
Ventricular Function, Right
Plasma Volume
Cardiovascular Physiological Phenomena
Heart Ventricles
Cerebral Hemorrhage
Blood Flow Velocity
Cerebral Infarction
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Central Venous Pressure
Risk Factors
Echocardiography, Doppler
Treatment Outcome
Oxygen Consumption
Monitoring, Physiologic
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Head-Down Tilt
Blood Volume Determination
Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.
Dogs
Cerebral Aqueduct
Physical Exertion
Echocardiography
Follow-Up Studies
Monitoring, Intraoperative
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Exercise Test
Lower Body Negative Pressure
Pulmonary Wedge Pressure
Lung Volume Measurements
Pulse
Respiration
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Cardiovascular Deconditioning
Recovery of Function
Exercise
Echocardiography, Three-Dimensional
Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)
Severity of Illness Index
Catheterization, Swan-Ganz
Placement of a balloon-tipped catheter into the pulmonary artery through the antecubital, subclavian, and sometimes the femoral vein. It is used to measure pulmonary artery pressure and pulmonary artery wedge pressure which reflects left atrial pressure and left ventricular end-diastolic pressure. The catheter is threaded into the right atrium, the balloon is inflated and the catheter follows the blood flow through the tricuspid valve into the right ventricle and out into the pulmonary artery.
Tomography, X-Ray Computed
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Magnetic Resonance Imaging, Cine
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
Compliance
Paresis
A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). "General paresis" and "general paralysis" may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.
Stroke, Lacunar
Plasma Substitutes
Brain Infarction
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Tissue Plasminogen Activator
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
Cardiac Catheterization
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Fluid Shifts
Translocation of body fluids from one compartment to another, such as from the vascular to the interstitial compartments. Fluid shifts are associated with profound changes in vascular permeability and WATER-ELECTROLYTE IMBALANCE. The shift can also be from the lower body to the upper body as in conditions of weightlessness.
Observer Variation
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Hypertension
Mitral Valve Insufficiency
Cardiovascular System
Echocardiography, Transesophageal
Orthostatic Intolerance
Symptoms of cerebral hypoperfusion or autonomic overaction which develop while the subject is standing, but are relieved on recumbency. Types of this include NEUROCARDIOGENIC SYNCOPE; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; and neurogenic ORTHOSTATIC HYPOTENSION. (From Noseworthy, JH., Neurological Therapeutics Principles and Practice, 2007, p2575-2576)
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Models, Cardiovascular
Erythrocyte Volume
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Fetal Heart
Tilt-Table Test
Hypotension, Orthostatic
A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
Image Processing, Computer-Assisted
Thrombolytic Therapy
Ventricular Pressure
The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.
Echocardiography, Doppler, Color
Pressure
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Intracranial Hemorrhages
Analysis of Variance
Oxygen
Intraoperative Care
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Incidence
Intra-Abdominal Hypertension
Reference Values
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Atrial Fibrillation
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Disease Models, Animal
Arterial Pressure
Physical Endurance
Imaging, Three-Dimensional
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Intracranial Embolism
Photoplethysmography
Vascular Capacitance
Heat Stroke
A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
Cardiotonic Agents
Respiratory Mechanics
Hemiplegia
Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.
Echocardiography, Four-Dimensional
Magnetic Resonance Angiography
Sensitivity and Specificity
Gated Blood-Pool Imaging
Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS).
Hypotension
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Pulmonary Artery
Respiration, Artificial
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
Dye Dilution Technique
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Dizziness
Myocardial Infarction
Diving
Hematocrit
Risk Assessment
Infusions, Intravenous
Prognosis
Aging
Multivariate Analysis
Supination
Double-Blind Method
Exercise Tolerance
Torsion, Mechanical
Hydroxyethyl Starch Derivatives
Dobutamine
Electrical Equipment and Supplies
Linear Models
Myocardium
Plethysmography, Impedance
Carotid Stenosis
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Algorithms
Adaptation, Physiological
Phonocardiography
Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.
Feasibility Studies
Thorax
Registries
Cardiac Output, Low
A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
Hospital Units
Heart Diseases
Image Interpretation, Computer-Assisted
Echocardiography, Doppler, Pulsed
Ventricular Remodeling
Cardiac Pacing, Artificial
Isotonic Solutions
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Comorbidity
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Baroreflex
A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.
Carbon Dioxide
Sex Characteristics
Endarterectomy, Carotid
Adrenergic beta-Antagonists
Water-Electrolyte Balance
Intracranial Thrombosis
Aortic Valve Stenosis
Pilot Projects
Risk
Positive-Pressure Respiration
Radionuclide Angiography
Dose-Response Relationship, Drug
Cardiac sympathetic activity estimated by 123I-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker or angiotensin-converting enzyme inhibitor therapy. (1/5911)
Impaired cardiac sympathetic activity can be evaluated by 123I-metaiodobenzylguanidine (MIBG) imaging. METHODS: We studied the significance of MIBG imaging for 24 patients (age 58+/-12 y) with dilated cardiomyopathy (DCM). We compared 12 patients (group A) treated with metoprolol (dose from 30-60 mg/d) with 12 patients treated with angiotensin-converting enzyme (ACE) inhibitors. Patients were studied before treatment, after 5 mo of treatment (only in group A) and after 1 y of treatment. Cardiac MIBG uptake was assessed as the heart-to-mediastinum activity ratio (H/M) and total defect score (TDS) from anterior planar and SPECT MIBG images, which were acquired in 4 h after tracer injection. New York Heart Association (NYHA) class and left ventricular ejection fraction (LVEF) calculated by echocardiography were also assessed. RESULTS: TDS decreased in both groups (in group A, from 30+/-7 through 23+/-9 to 18+/-10; P < 0.01, in group B, from 30+/-6 to 24+/-8; P < 0.01) and H/M was increased in both groups (in group A, from 1.87+/-0.31 through 2.03+/-0.28 to 2.14+/-0.29; P < 0.01, in group B, from 1.82+/-0.28 to 1.94+/-0.26; P < 0.05). But TDS and H/M were more improved in group A than in group B (P < 0.05). LVEF was significantly increased in only group A (from 38+/-6 through 43+/-8 to 49%+/-9%; P < 0.01). NYHA improved in both groups (in group A, from mean 2.5 through 2.1 to 1.8; P < 0.01, in group B, from mean 2.6 to 2.1; P < 0.05) but was more improved in group A than in group B (P < 0.05). CONCLUSION: Cardiac function, symptom and cardiac sympathetic activity evaluated by MIBG images improved after the beta-blocker therapy more than with the treatment that used ACE inhibitors. (+info)Sympathetic nerve alterations assessed with 123I-MIBG in the failing human heart. (2/5911)
Norepinephrine (NE) reuptake function is impaired in heart failure and this may participate in myocyte hyperstimulation by the neurotransmitter. This alteration can be assessed by 123I-metaiodobenzylguanidine (MIBG) scintigraphy. METHODS: To determine whether the impairment of neuronal NE reuptake was reversible after metoprolol therapy, we studied 18 patients (43+/-7 y) with idiopathic dilated cardiomyopathy who were stabilized at least for 3 mo with captopril and diuretics. Patients underwent, before and after 6 mo of therapy with metoprolol, measurements of radionuclide left ventricular ejection fraction (LVEF), maximal oxygen consumption and plasma NE concentration. The cardiac adrenergic innervation function was scintigraphically assessed with MIBG uptake and release measurements on the planar images obtained 20 min and 4 h after tracer injection. To evaluate whether metoprolol had a direct interaction with cardiac MIBG uptake and release, six normal subjects were studied before and after a 1-mo metoprolol intake. RESULTS: In controls, neither cardiac MIBG uptake and release nor circulating NE concentration changed after the 1-mo metoprolol intake. Conversely, after a 6-mo therapy with metoprolol, patients showed increased cardiac MIBG uptake (129%+/-10% versus 138%+/-17%; P = 0.009), unchanged cardiac MIBG release and decreased plasma NE concentration (0.930+/-412 versus 0.721+/-0.370 ng/mL; P = 0.02). In parallel, patients showed improved New York Heart Association class (2.44+/-0.51 versus 2.05+/-0.23; P = 0.004) and increased LVEF (20%+/-8% versus 27%+/-8%; P = 0.0005), whereas maximal oxygen uptake remained unchanged. CONCLUSION: Thus, a parallel improvement of myocardial NE reuptake and of hemodynamics was observed after a 6-mo metoprolol therapy, suggesting that such agents may be beneficial in heart failure by directly protecting the myocardium against excessive NE stimulation. (+info)Effects of tumour necrosis factor-alpha on left ventricular function in the rat isolated perfused heart: possible mechanisms for a decline in cardiac function. (3/5911)
1. The cardiac depressant actions of TNF were investigated in the isolated perfused rat heart under constant flow (10 ml min(-1)) and constant pressure (70 mmHg) conditions, using a recirculating (50 ml) mode of perfusion. 2. Under constant flow conditions TNF (20 ng ml(-1)) caused an early (< 25 min) decrease in left ventricular developed pressure (LVDP), which was maintained for 90 min (LVDP after 90 min: control vs TNF; 110 +/- 4 vs 82 +/- 10 mmHg, P < 0.01). 3. The depression in cardiac function seen with TNF under constant flow conditions, was blocked by the ceramidase inhibitor N-oleoylethanolamine (NOE), 1 microM, (LVDP after 90 min: TNF vs TNF with NOE; 82 +/- 10 vs 11 +/- 5 mmHg, P < 0.05). 4. In hearts perfused at constant pressure, TNF caused a decrease in coronary flow rate (change in flow 20 min after TNF: control vs TNF; -3.0 +/- 0.9 vs -8.7 +/- 1.2 ml min(-1), P < 0.01). This was paralleled by a negative inotropic effect (change in LVDP 20 min after TNF: control vs TNF; -17 +/- 7 vs -46 +/- 6 mmHg, P < 0.01). The decline in function was more rapid and more severe than that seen under conditions of constant flow. 5. These data indicate that cardiac function can be disrupted by TNF on two levels, firstly via a direct, ceramidase dependant negative inotropic effect, and secondly via an indirect coronary vasoconstriction. (+info)Stroke volume decline during prolonged exercise is influenced by the increase in heart rate. (4/5911)
This study determined whether the decline in stroke volume (SV) during prolonged exercise is related to an increase in heart rate (HR) and/or an increase in cutaneous blood flow (CBF). Seven active men cycled for 60 min at approximately 57% peak O2 uptake in a neutral environment (i.e., 27 degrees C, <40% relative humidity). They received a placebo control (CON) or a small oral dose (i.e., approximately 7 mg) of the beta1-adrenoceptor blocker atenolol (BB) at the onset of exercise. At 15 min, HR and SV were similar during CON and BB. From 15 to 55 min during CON, a 13% decline in SV was associated with an 11% increase in HR and not with an increase in CBF. CBF increased mainly from 5 to 15 min and remained stable from 20 to 60 min of exercise in both treatments. However, from 15 to 55 min during BB, when the increase in HR was prevented by atenolol, the decline in SV was also prevented, despite a normal CBF response (i.e., similar to CON). Cardiac output was similar in both treatments and stable throughout the exercise bouts. We conclude that during prolonged exercise in a neutral environment the decline in SV is related to the increase in HR and is not affected by CBF. (+info)Assessment of cardiac sympathetic regulation by respiratory-related arterial pressure variability in the rat. (5/5911)
1. Mechanical ventilation evokes a corresponding arterial pressure variability (APV) which is decreased by beta-adrenoceptor antagonism. Therefore, in this study we set out to determine whether the respiratory-related APV can be used to assess cardiac sympathetic tone. 2. Computer-generated broad-band mechanical ventilation (0-3 Hz) was applied to Sprague-Dawley rats that had been anaesthetized with ketamine and paralysed with pancuronium. APV and its relationship to lung volume variability (LVV-APV) was systematically quantified with auto- or cross-spectral frequency domain analysis. 3. APV and LVV-APV transfer magnitudes between 0.5 and 1.5 Hz showed dose-dependent suppression by propranolol from 0.01 to 1 mg kg-1, while the static value of arterial pressure remained unchanged. Stroke volume variability, assessed by the use of a pulse contour method, exhibited a similar pattern of suppression by propranolol. In contrast, heart rate variability was not lowered with propranolol. 4. The effect of propranolol on respiratory-related APV persisted even in the presence of combined alpha-adrenoceptor and muscarinic receptor blockade by phentolamine and atropine. 5. The frequency range of 0.5-1.0 Hz was optimal for LVV-APV transfer magnitude to correlate with cardiac sympathetic tone. 6. We conclude that respiratory-related APV may provide a valid assessment of cardiac sympathetic regulation which is independent of parasympathetic and vascular sympathetic influences in ketamine-anaesthetized and positive pressure-ventilated rats. (+info)Ryanodine and the left ventricular force-interval and relaxation-interval relations in closed-chest dogs: insights on calcium handling. (6/5911)
OBJECTIVE: Although the myocardial force-interval and relaxation-interval relations are considered to be mechanical expressions of myocardial Ca2+ handling, correlation of these phenomena with altered Ca2+ kinetics in the intact state is limited. Thus, I sought to determine the impact of selective impairment of physiologic sarcoplasmic reticulum Ca2+ release, achieved by the use of the drug ryanodine, on these relations in the intact animal. METHODS: Twelve dogs instrumented with left ventricular manometers and piezoelectric dimension crystals were studied before and after ryanodine (4 micrograms/kg intravenously). End-systolic elastance was measured at paced heart rates of 120-180 bpm to determine the force-frequency response. Mechanical restitution and relaxation restitution were determined by measuring contractile (single beat elastance) and relaxation (peak negative dP/dt) responses for beats delivered at graded extrasystolic intervals, with normalized responses expressed as a function of extrasystolic interval. RESULTS: Ryanodine accelerated mechanical restitution (time constant 60.3 +/- 3.9 versus 81.7 +/- 10.1 ms, p < 0.05) and reduced maximal contractile response (107.5 +/- 2.1 versus 122.1 +/- 5.7%, p < 0.05), slowed early relaxation restitution (time constant 65.5 +/- 13.8 versus 36.8 +/- 3.8 ms, p < 0.05) without changing late relaxation restitution kinetics, and amplified the force-frequency response (end-systolic elastance, 180 bpm, 19.4 +/- 4.3 versus 11.4 +/- 1.2 mm Hg/ml, p < 0.05). CONCLUSIONS: These findings suggest that in the intact animal, Ca2+ handling by the sarcoplasmic reticulum is a primary determinant of mechanical restitution and early relaxation restitution, but not late relaxation restitution. Conversely, ryanodine induced augmentation of the force-frequency response indicates a central role for sarcolemmal Ca2+ influx in producing frequency potentiation. (+info)Effect of bolus epinephrine on systemic hemodynamics in canine anaphylactic shock. (7/5911)
OBJECTIVE: Epinephrine (Epi) is considered to be the drug of choice for anaphylactic shock (AS). However, the benefit of this drug on improving systemic hemodynamics in AS has never been shown. We used a canine ragweed model of AS to determine if an intravenous bolus of Epi hastened the recovery of hemodynamics and modified mediator release (Med) compared with no treatment (NT). METHODS: In one protocol (n = 8), the effects on hemodynamics of two intravenous doses of Epi (0.01 and 0.025 mg/kg) were examined for 3 h postshock in respective studies approximately three weeks apart under pentobarbital anesthesia in the same animal. In five other dogs, left ventricular (LV) mechanics were additionally determined by sonomicrometric techniques to determine changes in contractility as defined by the preload recruitable stroke-work (SW) relationship. RESULTS: Compared with NT values, Epi treatments produced only transient increases in mean arterial pressure (MAP) and cardiac output (CO) post-challenge. By 20 min postshock, CO in the Epi studies were generally lower (p < 0.05) and BP was not different from NT values. With Epi treatment, SW was reduced for a given LV end-diastolic volume compared with the control study. Epi treatments also caused relatively higher plasma thromboxane B2 concentrations postshock. CONCLUSION: Our findings indicate that, when given immediately postshock, bolus-Epi did not hasten recovery and caused impairment in LV mechanics in canine AS. (+info)Study on propionyl-L-carnitine in chronic heart failure. (8/5911)
AIMS: In patients with chronic heart failure, fatigue is independent of haemodynamic and neuroendocrine changes and possibly may be due to impaired muscle metabolism. Propionyl-L-carnitine, a carnitine derivative, was shown in previous studies to improve muscle metabolism. The objective of this study was to evaluate the effect of propionyl-L-carnitine on exercise capacity in mild moderate chronic heart failure patients, treated with ACE inhibitors and diuretics. METHODS AND RESULTS: This was a phase III, double-blind, randomized, parallel, multicentre study. The primary objective was the evaluation of the effect of propionyl-L-carnitine vs placebo on maximum exercise duration using a bicycle exercise test. The primary analysis performed in the intention-to-treat population (271 and 266 patients in propionyl-L-carnitine and placebo), showed no statistically significant difference between treatments. A difference of 15 s in favour of propionyl-L-carnitine was observed in the completer/complier population (P=0.092). An a priori specified subgroup analysis on patients stratified by baseline maximum exercise duration showed a trend of improvement in propionyl-L-carnitine patients with shorter maximum exercise duration. A non a priori specified analysis in patients stratified by ejection fraction (< or = 30% vs 30-40%), showed a statistically significant difference in maximum exercise duration in favour of propionyl-L-carnitine in those patients with a higher ejection fraction (40 s, P<0.01). There were no safety issues. CONCLUSION: The study fails to meet the primary objective, but confirms the good safety profile of propionyl-L-carnitine. An exploratory non-prespecified analysis suggests that propionyl-L-carnitine improves exercise capacity in patients with preserved cardiac function. This hypothesis needs to be confirmed by a specific tailored study. (+info)
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Acute and Chronic Effect of His-pacing in Consecutive Patients With AV-block - Full Text View - ClinicalTrials.gov
Decreased left ventricular ejection fraction in transgenic mice expressing mutant cardiac troponin T-Q<sup>92</sup>,...
PROGNOSTIC STRATIFICATION IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFACTION OVER TRANSTHORACIC ECHOCARDIOGRAPHY BY CMR | JACC:...
LCZ696 Compared to Valsartan in Patients With Chronic Heart Failure and Preserved Left-ventricular Ejection Fraction - Tabular...
Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM...
Tachycardia-Induced Diastolic Dysfunction and Resting Tone in Myocardium From Patients With a Normal Ejection Fraction | JACC:...
MJB Journal : Study of Minor Echocardiographic Indices of Cardiac Systolic Function in Subjects with Normal Ejection Fraction...
Impact of renin-angiotensin system blockade on the prognosis of acute coronary syndrome based on left ventricular ejection...
Continuous Measurement of Left Ventricular Ejection Fraction during Isometric Handgrip (Ihg) and Cold Stress (Cs) in Normal...
Assessment of left ventricular ejection fraction in patients eligible for ICD therapy: Discrepancy between cardiac magnetic...
Use Simpsons Rule with n = 10 to estimate the arc length of the curve
Dr Austin Ng - The University of Sydney
Most recent papers with the keyword Euvolemia | Read by QxMD
Rationale and design of the strain surveillance of chemotherapy for improving cardiovascular outcomes: the SUCCOUR trial
End systolic volume - DocCheck Flexikon
preserved ejection fraction | healthPlexus.net
Ejection fraction
Do You Know Your Ejection Fraction? - The Womens Journal
Women with left ventricular ejection fraction | or = 20% have better prognosis than men. - Semantic Scholar
How to Determine Stroke Volume - iTags
Plus it
α<sub>2c</sub>Del322-325 and β<sub>1</sub>Arg389 Adrenergic Polymorphisms Are Not Associated With Reduced Left Ventricular...
Causes of an Abnormal Ejection Fraction
Mecal Magnetic Separator Cme
Ejection Fraction question - Heart Disease - MedHelp
Instantaneous measurement of left and right ventricular stroke volume and pressure-volume relationships with an impedance...
Reproducibility in the analysis of multigated radionuclide studies of left ventricular ejection fraction<...
Meta-analysis of Risk of Ventricular Arrhythmias After Improvement in Left Ventricular Ejection Fraction During Follow-Up in...
Left ventricular diastolic and systolic dyssynchrony and dysfunction in heart failure with preserved ejection fraction and a...
Association of Obstructive Sleep Apnea Indicators with Heart Failure
| Proceedings of IMPRS
Response to Latest British Society of Echocardiography recommendations for left ventricular ejection fraction categorisation:...
Clinical outcomes of patients with impaired left ventricular ejection fraction undergoing autologous bone marrow...
Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction - Research database ...
A Model Simulation for Decreased Left Ventricular Stroke Volume in Obstructive Sleep-Disordered Breathing
Comparison of echocardiography with technetium 99m-gated single photon emission computed tomography as diagnostic tools for...
Poor Correlation Between Pulmonary Arterial Wedge Pressure and Left Ventricular End-diastolic Volume after Coronary Artery...
Research and Opinion in Anesthesia & Intensive Care : Table of Contents
Research and Opinion in Anesthesia & Intensive Care : Table of Contents
Preload Assessment in Trauma Patients During Large-Volume Shock Resuscitation | JAMA Surgery | JAMA Network
Accuracy of the long-axis area-length method for the measurement of left ventricular volumes and ejection fraction using...
Association between cognitive function and parameters of echocardiography and coronary artery angiography - Majid Barekatain
A comparison of visual and quantitative assessment of left ventricular ejection fraction by cardiac magnetic resonance. -...
Heart failure with mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF)] | eLitMed
PRIME PubMed | Association of Abnormal Left Ventricular Functional Reserve With Outcome in Heart Failure With Preserved...
Pulse pressure variation, stroke volume variation and dynamic arterial elastance | Critical Care | Full Text
Stroke volume variation to guide fluid therapy: is it suitable for high-risk surgical patients? A terminated randomized...
Right ventricular ejection fraction during exercise in patients with recent myocardial infarction: effect of the...
Rest and nitroglycerine myocardial viability scan - Cardiophile MD Archive
WHAT IS HEART FAILURE? - UK
ARTICLES | Physiological Genomics
Right ventricular volume measurement with single-plane Simpsons method based on a new half-circle model - Fingerprint
-...
Ejection fraction
719 Dilated cardiomyopathy: alternative treatment with resynchronization cardiac and stem cells therapy: Preliminary results
Right-Sided Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction and Worsening Renal Function<...
Intracardiac echocardiographic measurement of left ventricular volume<...
ANZCTR - Registration
Impaired myocardial function does not explain reduced left ventricular filling and stroke volume at rest or during exercise at...
Tufts Medical Center | Heart Failure 12598
Time-dependent regional myocardial strains in patients with heart failure with a preserved ejection fraction<...
Left ventricular ejection fraction: morbidity, mortality and use of resources in a cardiac intensive care unit
Point Of Care Ultrasound (pocus) Auto Ef Computer Learning
Diagnostic and Prognostic Use of Myocardial Strain in Patients with Acute Myocardial Infarction
Effect of Plethora and Hemorrhage on Left Ventricular Volume and Pressure | Circulation Research
Continuous ejection fraction estimation by model-based analysis of an aortic pressure waveform: comparison to echocardiography.
DI-fusion Influence of respiratory rate on stroke volume variation in...
Exercise
Aerobic exercise can cause several central cardiovascular adaptations, including an increase in stroke volume (SV)[104] and ... "Physiological outcomes of aerobic exercise training in hemiparetic stroke patients". Stroke: A Journal of Cerebral Circulation ... Without proper rest, the chance of stroke or other circulation problems increases,[82] and muscle tissue may develop slowly. ... volume, and intensity remain to be determined. .... Conclusion. Few interventions exist whereby patients can hope to achieve ...
Esophageal doppler
The product of stroke distance and aortic constant gives stroke volume (how much blood was ejected from a heartbeat into the ... It is minimally invasive (does not break the skin) and is used to derive hemodynamic parameters such as stroke volume (SV) and ... Cardiac output (CO) is the product of stroke volume and heart rate. Although CO is available beat by beat, it is usually ... such as stroke volume (SV), flow-time corrected (FTc) and cardiac output (CO). Using manual input of age, weight and height; ...
Effects of high altitude on humans
In addition, at high altitude, the heart beats faster; the stroke volume is slightly decreased; and non-essential bodily ... Faeh, David; Gutzwiller, Felix; Bopp, Matthias (2009). "Lower Mortality From Coronary Heart Disease and Stroke at Higher ... enlarged lung volumes throughout life, and a higher capacity for exercise. Tibetans demonstrate a sustained increase in ... decreased plasma volume, increased hematocrit (polycythemia), increased RBC mass, a higher concentration of capillaries in ...
Cardiovascular physiology
Stroke volume (= end-diastolic volume − end-systolic volume) Ejection fraction (= stroke volume / end-diastolic volume) Cardiac ... Suction volume (= end-systolic volume + end-diastolic volume) Injection fraction (=suction volume / end-systolic volume) ... Cardiac output (= heart rate * stroke volume. Can also be calculated with Fick principle.) ... Stroke volume Cardiac output Pressure Pulse pressure (systolic pressure - diastolic pressure) Mean arterial pressure (usually ...
Engine displacement
One complete cycle of a four-cylinder, four-stroke engine. The volume displaced is marked in orange. ... stroke length. ×. π. ×. (. 1. 2. ×. bore. ). 2. ×. number of cylinders. {\displaystyle {\text{Displacement}}={\text{stroke ... "Swept volume" redirects here. For the 3D display technology, see Swept-volume display. ... Engine displacement is the swept volume of all the pistons inside the cylinders of a piston engine. The engine displacement ...
Heart
Ejection fraction can then be obtained by dividing the volume ejected by the heart (stroke volume) by the volume of the filled ... using an average stroke volume of about 70mL, is 5.25 L/min, with a normal range of 4.0-8.0 L/min.[7] The stroke volume is ... stroke volume) in one minute. This is calculated by multiplying the stroke volume (SV) by the beats per minute of the heart ... The strength of heart muscle contractions controls the stroke volume. This can be influenced positively or negatively by agents ...
Cardiac physiology
... controls the stroke volume which determines the end systolic volume. The greater the contraction the greater the stroke volume ... This quantity is referred to as stroke volume. Stroke volume will normally be in the range of 70-80 mL. Since ventricular ... stroke volume, SV) in one minute. To calculate this, multiply stroke volume (SV), by heart rate (HR), in beats per minute. It ... stroke volume is dependent upon the difference between end diastolic volume and end systolic volume. The three primary factors ...
Ventricle (heart)
... including end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and ejection fraction (Ef). ... Pumping volume[edit]. The typical healthy adult heart pumping volume is ~5 liters/min, resting. Maximum capacity pumping volume ... Stroke volume / body surface area (mL/m2) 51 mL/m2 (± 7 mL/m2)[2] 52 mL/m2 (± 6.2 mL/m2)[3] ... End-diastolic volume / body surface area (mL/m2) 78 mL/m2 (± 11 mL/m2)[2] 78 mL/m2 (± 8.8 mL/m2)[3] ...
Framingham Heart Study
"Genetic variation in white matter hyperintensity volume in the Framingham Study". Stroke. 35 (7): 1609-13. doi:10.1161/01.str. ... Elevated blood pressure increases risk of stroke. In women who are postmenopausal, risk of heart disease is increased, compared ... Having an enlarged left ventricle of the heart (left ventricular hypertrophy) increases risk of stroke. Elevated blood pressure ... with no history of heart attack or stroke. Due to lukewarm interest at first, doctors, nurses and healthcare workers ...
Rural poverty
... hospital volume, and stroke fatality in Canada". Stroke. 39 (12): 3360-3366. doi:10.1161/STROKEAHA.108.521344. PMID 18772443.. ... Volume 9, Number 1, February, pp 69-86. Wagao, J. (1992) "Adjustment Policies in Tanzania, 1981-9: The Impact of Growth, ...
Bainbridge reflex
"Effects on cardiac contractility and stroke volume are insignificant." Bainbridge reflex can be blocked by atropine and can be ... Increased blood volume is detected by stretch receptors (Cardiac Receptors) located in both sides of atria at the venoatrial ... In contrast, the Bainbridge reflex responds to changes in blood volume. The Bainbridge reflex is seen in dogs, but experiment ... Increased blood volume results in increased venous return to the heart, which leads to increased firing of B-fibers. B-fibers ...
Müller's sign
... is caused by an increased stroke volume.{{cn Müller's sign is named for Friedrich von Müller, a German physician ...
Heart failure with preserved ejection fraction
Cardiac output is dependent on stroke volume and heart rate. A significant portion (55-77%) of HFpEF patients are unable to ... Combined with the characteristic deficit in stroke volume observed in HFpEF patients, many individuals display poor exercise ... the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when ... It may be misguided to classify the volume-overloaded heart as having diastolic dysfunction if it is behaving in a stiff and ...
Quantium Medical Cardiac Output
Frazier, J. (2007). "Stroke Volume Variation' Can We Use Fluid to Improve haemodynamics?". Clin. Mark. Edwards Lifesciences. ... Usually for calculating the stroke volume, the methods based on pulse wave analysis need previous and periodic calibrations ... and Stroke Volume (SV). The SV in turn, depends on three general factors: pre-load, post-load and myocardial contractility.[ ... and other hemodynamic parameters such as the Stroke Volume (SV) and Cardiac index (CI). The CO estimated by the qCO monitor is ...
Pathophysiology of hypertension
Cardiac output is determined by stroke volume and heart rate; stroke volume is related to myocardial contractility and to the ... Persistent hypertension is a major risk factor for hypertensive heart disease, coronary artery disease, stroke, aortic aneurysm ... The autonomic nervous system plays a central role in maintaining cardiovascular homeostasis via pressure, volume, and ... Another system maintaining the extracellular fluid volume, peripheral resistance, and that if disturbed may lead to ...
Gypsy jazz
The down stroke is preferred because of volume and tone. While this technique of doubling down strokes varies among players, ... Horowitz, Michael (2007), Gypsy Rhythm, Volume 1, Djangobooks.com "Ornamented Arpeggios: Free Jazz Guitar Soloing Lesson 7 by ... the traditional technique is to use a down stroke. For instance, on switching from the G to the B string, the plectrum will ...
Anzani 3-cylinder fan engines
Contemporary sources differ on its bore, stroke and swept volume. The first description of the successful machine in Flight ... Output power: bore×stroke: capacity 10-12 hp (7.5-9 kW) 3.35 in × 3.35 in (85 mm × 85 mm): 88.5 cu in (1.45 L) 12-15 hp (9-11 ... but strokes between 120 and 150 mm (4.72 and 5.90 in) are quoted. Most put the output of these engines at about 18 kW (24 hp) ... partly to minimise volume and partly to help cool the hot exhaust valve. Most contemporary and pre-1921 sources agree that the ...
Essential hypertension
Cardiac output is determined by stroke volume and heart rate; stroke volume is related to myocardial contractility and to the ... When sodium intake exceeds the capacity of the body to excrete it through the kidneys, vascular volume expands secondary to ... The increase in blood volume leads to hypertension. An overactive sympathetic nervous system, leading to increased stress ...
Digitalis
... stroke volume is increased. Ultimately, digitalis increases cardiac output (cardiac output = stroke volume x heart rate). This ...
Hasidic Judaism
Many of them wear a black silk bekishe that is trimmed with velvet (known as stro-kes or samet) and in Hungarian ones, gold- ... a b Joseph Dan, A Bow to Frumkinian Hasidism, Modern Judaism, Volume 11, pp. 175-193. ... Volume 8, p. 408. *^ Mendel Piekarz, Ben ideʼologyah li-metsiʼut, Bialik Institute (1994), .mw-parser-output cite.citation{font ... translated by Olga Marx; foreword by Chaim Potok (Paperback: 2 volumes in 1 ed.). New York: Schocken Books. ISBN 0-8052-0995-6 ...
Diving reflex
Plasma volume, stroke volume, and cardiac output remain higher than normal during immersion. The increased respiratory and ... Stroke volume is not greatly affected by immersion or variation in ambient pressure, but bradycardia reduces the overall ... Lung volume decreases in the upright position due to cranial displacement of the abdomen due to hydrostatic pressure, and ... Medical Aspects of Harsh Environments, Volume 1. pp. 531-552. Retrieved 12 October 2016.. ...
Hanyu Da Cidian
Volume 13 has both pinyin and stroke count indexes, plus appendices. A separate index volume (1997) lists 728,000 entries for ... 2 volumes. 3-volume edition (ISBN 7-5432-0304-9/ISBN 978-7-5432-0015-9): ?th impression (1999-06-01) 2-volume edition (ISBN 7- ... Publication of the thirteen volumes began with first volume in 1986 and ended with the appendix and index volume in 1994. The ... 22 volumes. ?th impression (2008-08-??) 23-volume edition (漢語大詞典) (ISBN 978-7-5326-2782-0): 23 volumes (12+1 index+14 addition ...
John Parsons Shillingford
Zacharoulis, A. A.; Evans, T. R.; Ziady, G. M.; Coltart, D. J.; Shillingford, J. P. (1975). "Measurement of stroke volume from ... "Effect of respiration on venous return and stroke volume in cardiac tamponade". British Heart Journal. 32 (5): 592-596. doi: ... "John Parsons Shillingford". Munk's Roll, Volume XI, Royal College of Physicians. Shillingford, M. (27 November 1999). "Obituary ...
Blood pressure
Cardiac output is the product of stroke volume and heart rate. Stroke volume is influenced by 1) the end diastolic volume or ... This results in a rapid decrease in central blood volume and a reduction of ventricular preload which in turn reduces stroke ... The magnitude of the pulse pressure is usually attributed to the interaction of the stroke volume of the heart, the compliance ... In the short-term, the greater the blood volume, the higher the cardiac output. This has been proposed as an explanation of the ...
Afterload
Cardiac output is the product of stroke volume and heart rate. Afterload is a determinant of stroke volume (in addition to ... the tension upon the muscle fibers in the heart wall is the pressure within the ventricle multiplied by the volume within the ... create a greater tension to overcome the same aortic pressure to eject blood because it has a larger internal radius and volume ...
Werner Hacke
The stroke center in Heidelberg is a high volume, hyperacute service. Many treatment- and diagnosis related innovations have ... He is a top-ranked author for publications in stroke and stroke therapy both by number and by citations in the last decade. ... In 2020 he received the WSO Leadership in Stroke Award. He is an honorary member of the Austrian and the Hungarian Stroke ... Prof Hacke was the Founding President of the European Stroke Organisation (ESO). He was co-chair of the 2006 World Stroke ...
Valsalva maneuver
The fall in stroke volume reflexively causes blood vessels to constrict with some rise in pressure (15 to 20 seconds). This ... This causes a mild rise in stroke volume during the first few seconds of the maneuver. Reduced venous return and compensation ... The output of the heart is reduced and stroke volume falls. This occurs from 5 to about 14 seconds in the illustration. ... The stroke volume usually rises above normal before returning to a normal level. With return of blood pressure, the pulse rate ...
Athletic heart syndrome
This type of exercise also increases both heart rate and stroke volume of the heart. Both static and dynamic exercises involve ... The heart becomes enlarged, or hypertrophic, due to intense cardiovascular workouts, creating an increase in stroke volume, an ... It also moderately increases heart rate and stroke volume (oxygen debt). Dynamic exercises include running, swimming, skiing, ... and normal extracellular volume. Athlete's heart is not dangerous for athletes (though if a nonathlete has symptoms of ...
March 1963
ISBN 978-0-905222-07-3. Casey, Phil (1963-03-05). "Poet Williams Dies of Stroke. Works in 40 Volumes Likened to Chekhov". ... William Carlos Williams, 79, American poet, of a stroke In Camden, Tennessee, country music superstar Patsy Cline (Virginia ... Volume 7: From Nadir Shah to the Islamic Republic (Cambridge University Press, 1991) p753 "Loyola New College Cage Champ", San ...
William Carlos Williams
ISBN 0-321-01556-8 Casey, Phil (1963-03-05). "Poet Williams Dies of Stroke. Works in 40 Volumes Likened to Chekhov". Washington ... Williams suffered a heart attack in 1948, and after 1949, a series of strokes. Severe depression after one such stroke caused ... Later collaborations with artists include the two poem/ two drawing volume that he shared with William Zorach in 1937 and his ... Williams won the first National Book Award for Poetry, recognizing both the third volume of Paterson and Selected Poems. In ...
Type 2 diabetes
Hyperosmolar hyperglycemic state, diabetic ketoacidosis, heart disease, strokes, diabetic retinopathy, kidney failure, ... CS1: long volume value. *CS1 maint: multiple names: authors list. *Wikipedia indefinitely semi-protected pages ... strokes, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to ... including ischemic heart disease and stroke; a 20-fold increase in lower limb amputations, and increased rates of ...
Liquefied natural gas
The (volume-based) energy density of LNG is approximately 2.4 times that of CNG which makes it economical to transport natural ... and still have time to complete the combustion process during the power stroke. ... However, when liquefied, it can be stored in a volume 1/600th as large. This is a practical way to store it but the gas must be ... Because of large volumes it is not practical to store natural gas, as a gas, near atmospheric pressure. ...
Violin technique
No matter which attack or bow stroke is used, most professional violinists use a straight bow stroke, keeping the bow ... Frederick Neumann and Ivan Galamian, Contemporary Violin Technique, Volume 2: Double and Multiple Stops in Scale and Arpeggio ... sometimes arrow-head strokes, and sometimes the stroke is simply left to the performer's discretion. spiccato and sautillé are ... Arpeggio, arpeggiando, arpeggiato - A bouncing stroke, played on broken chords, so that each note of the arpeggio is played on ...
Positron emission tomography
FDG-PET imaging of atherosclerosis to detect patients at risk of stroke is also feasible and can help test the efficacy of ... This necessitates frequent recalibration of the remaining dose (determination of activity per unit volume) and careful planning ... then reconstruct the entire volume together (3D). ...
Leaf
Vein raised above surrounding surface so to be easily felt when stroked with finger. e.g. (see) Pimenta racemosa,[66] ... Verdcourt, Bernard; Bridson, Diane M. (1991). Flora of tropical East Africa - Rubiaceae Volume 3. CRC Press. ISBN 978-90-6191- ... in Rines (1920) Volume XVII. *. James, S. A.; Bell, D. T. (2000). "Influence of light availability on leaf structure and growth ...
Psychogenic non-epileptic seizure
... and stroke. However, between 5-20% of people with PNES also have epilepsy.[15] Frontal lobe seizures can be mistaken for PNES, ... CS1: long volume value. *CS1 maint: others. *Articles with short description. *Articles with long short description ...
Smoking ban
e.g. mentioned on p. 167 in [1] Econ Journal Watch, Volume 5, Number 2, pp. 163-168. Retrieved 19 November 2009. ... "Smoking bans cut number of heart attacks, strokes". USA Today. Retrieved 5 September 2015 ... tobacco industry volume. Smokers facing these restrictions consume 11%-15% less than average and quit at a rate that is 84% ...
Reinhold Niebuhr
Volume one: Human Nature, Volume two: Human Destiny. Reprint editions include: Prentice Hall vol. 1: ISBN 0-02-387510-0, ... "Only a severe stroke prevents me from accepting ... I hope there will be a massive demonstration of all the citizens with ... a b Khurram Hussain, "Tragedy and History in Reinhold Niebuhr's Thought", American Journal of Theology and Philosophy, Volume ... These windmills must have tumbled shortly thereafter for every succeeding volume expresses a more and more explicit revolt ...
Radiography
CS1: long volume value. *All articles with unsourced statements. *Articles with unsourced statements from August 2020 ...
Joe E. Brown
Brown was incapacitated by a stroke several years ago, and he had suffered from severe arthritis.. .mw-parser-output cite. ... Volume 49, page 1. ...
German submarine U-559
Volume Two: North African Desert February 1952 - March 1943. London: Grub Street. ISBN 978-1-909166-12-7. .. ... The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of ...
Constantine Samuel Rafinesque
1828-1830: Medical Flora, a Manual of the Medical Botany of the United States of North America (two volumes). Philadelphia. ... 42:"This page of Demotic has letters and numbers, these represented by strokes meaning 5 and dots meaning unities as the dots ... 1836: The American Nations (two volumes). Philadelphia.. *1836: A Life of Travels and Researches in North America and South ... In 1836, Rafinesque published his first volume of The American Nations. This included Walam Olum, a purported migration and ...
List of governors general of Canada
Chief Justice Bora Laskin while Governor General Jules Léger was recovering from a stroke (July 2 to December 9, 1974);[42] ... CS1: long volume value. *CS1 errors: requires URL. *Articles with short description ...
GABAA receptor positive allosteric modulator
Stroke[edit]. Preclinical studies have shown that benzodiazepines can be effective in reducing the effect of strokes for up to ...
Venturi effect
Aortic insufficiency is a chronic heart condition that occurs when the aortic valve's initial large stroke volume is released ... Further, that the shape of the meter should be trumpet-shaped in both directions; such a meter will measure volumes flowing in ...
Titãs
Volume Dois (1998)) "Best band" (1987, 1988, 1989, 1997, 1998), and "Best show" (Titãs - Volume 2 - Ao Vivo, 1998) ... It was a hard stroke to the band, which started recording their new album the day after. A Melhor Banda de Todos os Tempos da ... This record was followed by Volume Dois (1998), modeled in the same way of their unplugged album, only recorded in studio; and ... Volume Dois (1999[50])), "Best show" (Titãs - Acústico MTV, 1998[50]), "Best song" (É Preciso Saber Viver, 1999[50]) and "Best ...
Free will
N-Z, Indeks, Volume 1. Psychology Press. pp. 197 ff. ISBN 0415939275.. CS1 maint: Uses editors parameter (link) ... either when it is severed to treat intractable epilepsy or due to a stroke. The standard neurological explanation is that the ... Oxford Handbook of Human Action (Volume 2 of Social Cognition and Social Neuroscience ed.). Oxford University Press. pp. 487 ff ... Oxford Handbook of Human Action (Volume 2 of Social Cognition and Social Neuroscience ed.). Oxford University Press. pp. 487 ff ...
Khat
stroke following acute coronary syndrome (clogging of the artery)[note 1][7]:12[29] ... Thomson Gale (Firm), Countries of the World and Their Leaders Yearbook 2007, Volume 1, (Thomson Gale: 2006), p.545. ... Dickens, Charles (1856) [Digitized February 19, 2010]. "The Orsons of East Africa". Household Words: A Weekly Journal, Volume ...
ادرار کردن - ویکیپدیا، دانشنامهٔ آزاد
In the adult, the volume of urine in the bladder that normally initiates a reflex contraction is about 300-400 millilitres (11- ... Some paraplegic patients train themselves to initiate voiding by pinching or stroking their thighs, provoking a mild mass ... difference in bladder volume.[11][12] This is due to increased urethra length of large animals, which amplifies gravitational ... At low bladder volumes, afferent firing is low, resulting in excitation of the outlet (the sphincter and urethra), and ...
Moclobemide
Tiller JW (1992). "Post-stroke depression". Psychopharmacology. 106 Suppl: S130-3. doi:10.1007/bf02246257. PMID 1546128.. ... moclobemide has an intermediate elimination half life for systemic clearance and an intermediate volume of distribution.[117] ...
Music therapy
StrokeEdit. Music is useful in the recovery of motor skills.[38] In a study on stroke patients in the recovery phase, music ... Kobialka is a type of new age music that produces large volume music that has violins playing over the background of ... M.; Titova, E. Yu.; Kriushev, E. S.; Gamaleya, A. A. (June 8, 2010). "Speech Disorders in Right-Hemisphere Stroke". ... Raglio, Alfredo (January 30, 2017). "Active music therapy approach for stroke patients in the post-acute rehabilitation". ...
Methanol fuel
In their traditionally popular two-stroke and increasingly popular four-stroke forms, currently produced single cylinder ... of volume, and can be as much as 25 to 30% of the total fuel volume. ... on volume or mass bases) will be higher than hydrocarbon fuels. The extra water produced also makes the charge rather wet ( ... 1 mix of white gas and heavy viscosity motor oil for the two-stroke spark ignition engines used for the hobby at that time. By ...
Straight-three engine
Four-stroke[edit]. Four-stroke straight-three motorcycle engines have been produced for both road and racing purposes[30] by ... Cycle world, Volume 44. CBS Publications, 2005 *^ Gorant, Jim (December 1997). Oldham, Joe (ed.). "Jet Ski Saviors". Popular ... Cycle world, Volume 44 CBS Publications, 2005. "inline triple" *^ Triumph enters Grand Prix racing as Moto2 engine supplier The ... The smallest inline-three, four-stroke automobile engine was the 543 cubic centimetres (33.1 cu in) Suzuki F5A, which was first ...
肥胖症 - 维基百科,自由的百科全书
Obesity - Volume 1 - HCP 23-I, Third Report of session 2003-04. Report, together with formal minutes. London, UK: TSO (The ... and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants.. ... Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin. Endocrinol. ( ...
Tea
The Chinese character for tea is 茶, originally written with an extra stroke as 荼 (pronounced tú, used as a word for a bitter ... Volume 1. South Asia Books. pp. 94-95. ISBN 978-8120604131.. CS1 maint: Uses authors parameter (link) ...
Written Chinese
Strokes[edit]. Main article: Stroke (CJK character). Character components can be further subdivided into strokes. The strokes ... Thorp, Robert L. "The Date of Tomb 5 at Yinxu, Anyang: A Review Article," Artibus Asiae (Volume 43, Number 3, 1981): 239-246. ... The radicals are ordered first by stroke count (that is, the number of strokes required to write the radical); within a given ... There are eight basic rules of stroke order in writing a Chinese character: *Horizontal strokes are written before vertical ...
多囊卵巢綜合症 - 维基百科,自由的百
PCOS, coronary heart disease, stroke and the influence of obesity: a systematic review and meta-analysis. Hum. Reprod. Update. ... an ovarian volume of at least 10 ml is regarded as an acceptable definition of having polycystic ovarian morphology instead of ...
Uniflow steam engine
The inlet valves open to admit steam when minimum expansion volume has been reached at the start of the stroke. For a period of ... allowing continued expansion of the steam during the stroke, driving the piston. Near the end of the stroke, the piston will ... Home-made conversions of two-stroke engines[edit]. The single-acting uniflow steam engine configuration closely resembles that ... The inertia of the flywheel then carries the piston back to the top of its stroke against the compression, as it does in the ...
Neuroscience of music
Wilson, Sarah J; Pressing, Jeffrey L; Wales, Roger J (2002). "Modelling rhythmic function in a musician post-stroke". ... and gray matter volume in the primary motor and somatosensory areas, premotor areas, anterior superior parietal areas and in ... Thaut, M. H.; McIntosh, G. C.; Rice, R. R. (1997). "Rhythmic facilitation of gait training in hemiparetic stroke rehabilitation ... rhythmic auditory stimuli have been shown to improve walking ability in Parkinson's disease and stroke patients.[38][39] ...
High-altitude cerebral edema
One theory is that variations in brain size play a role, but the increase in brain volume from edema does not likely cause ... including stroke, intoxication, psychosis,[1] diabetic symptoms, meningitis,[19] or ingestion of toxic substances.[4] It should ...
Definitions of stroke volume - OneLook Dictionary Search
stroke volume: online medical dictionary [home, info] *stroke volume: Medical dictionary [home, info] *Stroke volume, Volume, ... stroke volume: Encyclopedia [home, info] Medicine (6 matching dictionaries). *Stroke volume, Volume, stroke: MedTerms.com ... stroke volume: Merriam-Webster.com [home, info] *stroke volume: Dictionary.com [home, info] *Stroke volume: Wikipedia, the Free ... stroke volume: Dictionary/thesaurus [home, info] Business (2 matching dictionaries). *stroke volume: Legal dictionary [home, ...
Stroke Part I: Basic and epidemiological aspects, Volume 92 - 1st Edition
Volume 92 - 1st Edition. Print Book & E-Book. ISBN 9780444520036, 9780702035388 ... Purchase Stroke Part I: Basic and epidemiological aspects, ... Stroke Part I: Basic and epidemiological aspects, Volume 92 1st ... Epidemiological implications of primary and secondary stroke prevention. Stroke recurrence and prognosis after stroke. ... This volume provides a vital and comprehensive resource on stroke, including research, diagnosis, prevention, and treatment ...
White matter hyperintensity volume is increased in small vessel stroke subtypes. - PubMed - NCBI
White matter hyperintensity volume is increased in small vessel stroke subtypes.. Rost NS1, Rahman RM, Biffi A, Smith EE, ... We determined WMH volume (WMHV) in cohorts of prospectively ascertained patients with acute ischemic stroke (AIS) ( ... Figure 1 Box plot graphic representation of white matter hyperintensity volume distribution by acute ischemic stroke subtype ( ... Greater WMH burden was associated with SV stroke compared with other ischemic stroke subtypes and, even more strongly, with ICH ...
Improvements of Crankcase Delivery Ratio in Two-Stroke Engines with Volume Intake System
The article presents the possibilities of improvements the crankcase delivery ratio in small two-stroke engines by modification ... of the inlet system by means of an additional side volume connected with the inlet pipe. The results of calculations from ... Citation: Mitianiec, W., "Improvements of Crankcase Delivery Ratio in Two-Stroke Engines with Volume Intake System," SAE ... Improvements of Crankcase Delivery Ratio in Two-Stroke Engines with Volume Intake System 1999-01-3334. ...
Right Hemisphere Grey Matter Volume and Language Functions in Stroke Aphasia
... Sladjana Lukic,1,2 Elena Barbieri,1,2 Xue Wang,1, ... This study examined the right hemisphere (RH) grey matter (GM) volume in a group of 40 individuals with stroke-induced chronic ... Few studies have examined GM volume in patients with cognitive impairments resulting from stroke. Stebbins et al. [53], using ... In line with the aforementioned studies showing structural changes after LH stroke, we expected differences in GM volume in the ...
Exercise and brain volume loss after stroke | The Heart Foundation
Using the latest brain imaging techniques, Amy and her team will accurately measure brain size in 100 stroke patients over one ... We offer a range of funding across a variety of categories for research into heart, stroke and blood vessel disease. ... They will identify which cardiovascular risk factors are associated with brain atrophy after stroke, and whether cardiovascular ... She is examining modifiable risk factors that may predict brain shrinkage (or atrophy) after a stroke. ...
Patent US5058583 - Multiple monopolar system and method of measuring stroke volume of the heart - Google Patents
... voltage between one of the monopolar electrodes in the ventricle and the pacemaker case and for calculating stroke volume ... includes a constant-current source for current injection into the volume of blood in the patients ventricle and an impedance ... A multiple monopolar system and method for measuring stroke volume of a patients heart. An intracardiac impedance catheter is ... measuring the patients stroke volume during said induced variations in heart rate, said step of measuring stroke volume ...
Stroke Volume/Pulse Pressure Ratio and Cardiovascular Risk in Arterial Hypertension | Hypertension
The ratio of stroke volume to pulse pressure (SV/PP) has been proposed as an indirect measure of total arterial compliance,1 2 ... Stroke Volume/Pulse Pressure Ratio and Cardiovascular Risk in Arterial Hypertension. Giovanni de Simone, Mary J. Roman, Michael ... Stroke Volume/Pulse Pressure Ratio and Cardiovascular Risk in Arterial Hypertension. Giovanni de Simone, Mary J. Roman, Michael ... Stroke Volume/Pulse Pressure Ratio and Cardiovascular Risk in Arterial Hypertension. Giovanni de Simone, Mary J. Roman, Michael ...
Eiko No Stroke (All 3 Volumes)
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Stroke volume - Wikipedia
In cardiovascular physiology, stroke volume (SV) is the volume of blood pumped from the left ventricle per beat. Stroke volume ... which is stroke volume divided by end-diastolic volume. Because stroke volume decreases in certain conditions and disease ... Stroke volume is an important determinant of cardiac output, which is the product of stroke volume and heart rate, and is also ... Heart rate and Stroke Volume are unfixed. Men, on average, have higher stroke volumes than women due to the larger size of ...
Stroke Volume Calculation | BCC Health
Stroke Volume Calculation - If the infection is gentle and considerably localized then to treat toenail fungus a medical doctor ... Read More - Signs Of Heat Stroke In Babies. Hay fever allergies, also recognized as respiratory allergies surprising affects of ... Read More - Ebony Family Strokes. Every single time these antibodies recognize the identical invading allergens histamine is ...
Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke - Full Text View - ClinicalTrials.gov
Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke (ACTION). The safety and scientific validity of this study is ... Change in Infarct Volume From Day 5 (FLAIR) to Day 30 (FLAIR) [ Time Frame: Day 5, Day 30 ]. Relative growth of infarct volume ... Diagnosis of acute ischemic stroke.. *Score of ≥6 points on the National Institute of Health Stroke Scale (NIHSS) at Screening. ... on Reducing Infarct Volume in Acute Ischemic Stroke. ... Change in Infarct Volume From 24 Hours (FLAIR) to Day 5 (FLAIR ...
Respiration-synchronous fluctuations in stroke volume, heart rate and arterial pressure in humans
Simultaneous recordings of beat-to-beat left cardiac stroke volume (SV, pulsed ultrasound Doppler), mean arterial pressure (MAP ... Respiration-synchronous fluctuations in stroke volume, heart rate and arterial pressure in humans J Physiol. 1993 Dec;472:501- ... 1. Simultaneous recordings of beat-to-beat left cardiac stroke volume (SV, pulsed ultrasound Doppler), mean arterial pressure ( ...
Stroke Rehabilitaiton, An Issue of Physical Medicine and Rehabilitation Clinics of North America, Volume 26-4 - 1st Edition
Volume 26-4 - 1st Edition. Print Book & E-Book. ISBN 9780323413480, 9780323413497 ... Purchase Stroke Rehabilitaiton, An Issue of Physical Medicine and Rehabilitation Clinics of North America, ... Stroke Rehabilitaiton, An Issue of Physical Medicine and Rehabilitation Clinics of North America, Volume 26-4 1st Edition. ... Mechanisms of stroke recovery, Insights from basic sciences, Stroke recovery and predictors of rehabilitation outcomes, Upper ...
Noninvasive, simultaneous, and continuous measurements of stroke volume and tidal volume using EIT: feasibility study of animal...
... tidal volume and stroke volume were computed as valley-to-peak values of the RVS and CVS, respectively. The difference in the ... we use the EIT technique to simultaneously measure two global variables of tidal volume and stroke volume. Time-varying ... The difference in the stroke volume data between EIT and TPTD was within ± 4.7 ml from the same animals. The results show the ... The respiratory volume signal (RVS) and cardiac volume signal (CVS) were extracted from reconstructed time-difference EIT ...
Stroke Risk Profile Predicts White Matter Hyperintensity Volume | Stroke
Stroke Risk Profile Predicts White Matter Hyperintensity Volume. The Framingham Study. Tom Jeerakathil, Philip A. Wolf, Alexa ... Stroke Risk Profile Predicts White Matter Hyperintensity Volume. Tom Jeerakathil, Philip A. Wolf, Alexa Beiser, Joseph Massaro ... Stroke Risk Profile Predicts White Matter Hyperintensity Volume. Tom Jeerakathil, Philip A. Wolf, Alexa Beiser, Joseph Massaro ... Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins. Stroke. 1998; 29: 1177-1181. ...
Pressure-Flow Studies in Man: Effect of Respiration on Left Ventricular Stroke Volume | Circulation
... an immediate fall in stroke volume with the onset of inspiration; and (2) a subsequent increase in stroke volume presumably due ... Pressure-Flow Studies in Man: Effect of Respiration on Left Ventricular Stroke Volume. JEROME RUSKIN, ROBERT J. BACHE, JUDITH C ... In normals, stroke volume, systolic pressure, and pulse pressure fell an average of 7, 3 and 11% (P , 0.01), respectively, ... After breath-holding, stroke volume also fell immediately with the onset of inspiration in both groups. These results are ...
Volume 1, Issue 3, July 2006: Aphasia and Stroke Rehabilitation | National Rehabilitation Information Center
National Stroke Association. Toll Free: 800/787-6537, 303/649-9299 (V). Email: [email protected]stroke.org. www.stroke.org ... Information on type of stroke and individual stroke-related impairment was collected prospectively. Recurrent stroke, ... acute stroke patients and evaluate potential predictors for language outcome 1 year after stroke. METHODS: 270 acute stroke ... Information on stroke and rehabilitation is a common request. In this edition of reSearch, the topic of aphasia and stroke is ...
Contribution of Stroke Volume to the Change in Pulse Pressure Pattern With Age | Hypertension
... cardiac output gradually decreases at the expense of stroke volume.5 The age-related decrease in stroke volume, by reducing ... overcame the effect of the decreasing stroke volume on pulse pressure, explaining the lack of correlation between stroke volume ... without significant influence of stroke volume. Thus, in hypertensive men, the age-related change in stroke volume ... 12 Stroke index was obtained by dividing stroke volume by meters squared. Pulse pressure was calculated as the difference ...
Current Developments in Stroke:: volume 2 | Bentham Science
Current Developments in Stroke. Stroke is one of the most debilitating diseases which poses a significant economic burden on ... and air pollution are driving up the worldwide stroke burden. Although medical interventions to prevent and manage stroke have ... Stroke is one of the most debilitating diseases which poses a significant economic burden on society. Increasing exposure to ... This volume should be a useful guide for microbiologists and clinicians interested in designing antimicrobial therapies ...
The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model - SU - 2011 -...
The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model. Authors. *. E. ... Previous article in issue: Thrombomodulin analogues for the treatment of ischemic stroke Previous article in issue: ... A. P. ANDREOU, J. T. B. CRAWLEY, Thrombomodulin analogues for the treatment of ischemic stroke, Journal of Thrombosis and ... Background: Currently there is no approved anticoagulant for treating acute stroke. This is largely because of concern for ...
Whole Brain and Regional Hyperintense White Matter Volume and Blood Pressure | Stroke
Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins. Stroke. 1998; 29: 1177-1181. ... family history scores for stroke and hypertension to quantitative measures of white-matter hyperintensities and stroke volume ... subcortical and ependymal hyperintense white matter volume. Stroke. 2009; 40: 3685-3690. ... ependymal HWM volume and PP reached statistical significance (LOD=3.19). The linkage results for the subcortical HWM volume ...
Stroke volume | Article about stroke volume by The Free Dictionary
... the diastolic volume of the left ventricle minus the volume of blood in the... Explanation of stroke volume ... Find out information about stroke volume. The amount of blood pumped during each cardiac contraction; quantitatively, ... Stroke volume , Article about stroke volume by The Free Dictionary https://encyclopedia2.thefreedictionary.com/stroke+volume ... stroke volume. Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia. stroke volume. [′strōk ‚ ...
Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020 - Volume 26, Number 9-September 2020 - Emerging...
Volume 26, Number 9-September 2020 Research Letter. Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020 ... Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020. Volume 26, Number 9-September 2020 ... Lymphocyte-to-monocyte ratio: a novel predictor of the prognosis of acute ischemic stroke. J Stroke Cerebrovasc Dis. 2017;26: ... These cases involved presumed thrombotic stroke that occurred during ongoing anticoagulation for atrial fibrillation stroke ...
Annual Report: National Institute Of Neurological Disorders And Stroke Volume 1980 V.2, Book by National Institute Of...
Title:Annual Report: National Institute Of Neurological Disorders And Stroke Volume 1980 V.2Format:PaperbackDimensions:856 ... Annual Report: National Institute Of Neurological Disorders And Stroke Volume 1980 V.2. byNational Institute Of Neurological ... Customer Reviews of Annual Report: National Institute Of Neurological Disorders And Stroke Volume 1980 V.2. ...
Report Of Program Activities: National Institute Of Neurological Diseases And Stroke Volume 1968/69…, Book by National...
Title:Report Of Program Activities: National Institute Of Neurological Diseases And Stroke Volume 1968/69…Format:Paperback ... Report Of Program Activities: National Institute Of Neurological Diseases And Stroke Volume 1968/69…. byNational Institute Of ... Customer Reviews of Report Of Program Activities: National Institute Of Neurological Diseases And Stroke Volume 1968/69 V.2. ...
Figure - Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020 - Volume 26, Number 9-September 2020 -...
These cases highlight the severe and unique consequences of coronavirus disease-associated stroke. ... We describe 2 cases in coronavirus disease patients in France involving presumed thrombotic stroke that occurred during ongoing ... anticoagulation treatment for atrial fibrillation stroke prophylaxis; 1 patient had positive antiphospholipid antibodies. ... Volume 26, Number 9-September 2020 Research Letter. Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020 ...
Validation of Stroke Volume Measurement by a New Noninvasive Hemodynamic Monitoring System (NexFin)in Comparison to Different...
stroke volume [ Time Frame: preinduction, 3 and 15 minutes after induction, before and after a volume challenge, 30 minutes ... Validation of Stroke Volume Measurement by a New Noninvasive Hemodynamic Monitoring System (NexFin)in Comparison to Different ... In this study the stroke volume measured by a new noninvasive finger cuff system (NexFin) should be validated in comparison to ... Main hypothesis: there is no difference between stroke volume measurements recorded by a new noninvasive finger cuff system ( ...
Full text] Influence of stroke volume variation on fluid treatment and postoperat | TCRM
In the present study, we aimed to evaluate whether stroke volume variation (SVV) can guide fluid therapy and reduce ... Keywords: central venous pressure, fluid management, lobectomy, one-lung ventilation, stroke volume variation ... Influence of stroke volume variation on fluid treatment and postoperative complications in thoracic surgery Cengiz Sahutoglu, ... The SVV, cardiac output, cardiac index (CI), stroke volume, and stroke volume index (SVI) were measured by the FloTrac Device. ...
17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status
In contrast, it is not associated with lacunar stroke, suggesting that the association does not act by promoting small-vessel ... 17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status Stroke ... We aimed to replicate the association with WMH volume (WMHV) in patients with ischemic stroke. If the association acts by ... Methods: We quantified WMH on MRI in the stroke-free hemisphere of 2588 ischemic stroke cases. Association between WMHV and 6 ...
IschemicEjection fractionMiddle cerebral arteryVariationMETHODS2020Ischaemic strokeIncrease in stroke volumeSystolicClinicalCONCLUSIONSOutcomesDiastolic volumeRight ventricular stroke volumeOcclusionOutcomeArterial pressureDepartment of NeurologyAbstractPatients with nonvalvular atrial fibrillationLeft ventricularCentersPulmonaryMeasurementsCerebrovascularDecrease in stroke volumeNIHSSIncreasesPrognosisAtrialVesselIncreased vascularCorrelatesReduction in strokeEndovascular TherapyFinal infarct volumeReduces infarct volumeThrombosisInfarct volumesRecurrenceSignificantlyRespirationReperfusionMeasurementCardiac indexTherapiesThromboticLesion volumesVascular ResistanceInfarctionHemodynamicSystolePreload
Ischemic39
- Animal models of ischemic stroke. (elsevier.com)
- We determined WMH volume (WMHV) in cohorts of prospectively ascertained patients with acute ischemic stroke (AIS) (Massachusetts General Hospital [MGH], n = 628, and the Ischemic Stroke Genetics Study [ISGS], n = 263) and ICH (MGH, n = 122). (nih.gov)
- Greater WMH burden was associated with SV stroke compared with other ischemic stroke subtypes and, even more strongly, with ICH. (nih.gov)
- Because atrial fibrillation promotes the formation of blood clots that can travel to the brain and block an artery, atrial fibrillation independently increases the risk of ischemic stroke four-to-five-fold. (elsevier.com)
- Risk for ischemic stroke has a strong genetic basis, but heritable factors also contribute to the extent of damage after a stroke has occurred. (jci.org)
- The identification of neuroprotective genes based on naturally occurring allelic variations has the potential to inform the development of drug targets for ischemic stroke treatment. (jci.org)
- Our data indicate that Solulin is a safe and effective anticoagulant that is able to antagonize active thrombosis in acute ischemic stroke, and to reduce infarct volume. (wiley.com)
- Several studies have reported that acute ischemic stroke can develop in COVID-19 patients ( 1 - 6 ). (cdc.gov)
- Cerebral magnetic resonance image (MRI) showing acute ischemic stroke in multiple vascular areas of 2 coronavirus disease patients, France. (cdc.gov)
- Brain magnetic resonance imaging revealed acute ischemic stroke in multiple vascular areas ( Figure ). (cdc.gov)
- Several factors can cause acute ischemic stroke, but the primary ones are arterial and cardiac embolism, arterial wall disease, and variants of those conditions. (cdc.gov)
- We aimed to replicate the association with WMH volume (WMHV) in patients with ischemic stroke. (nih.gov)
- We quantified WMH on MRI in the stroke-free hemisphere of 2588 ischemic stroke cases. (nih.gov)
- Meta-analyses with previous reports and a genetic risk score approach were applied to identify other novel WMHV risk variants and uncover shared genetic contributions to WMHV in community participants without stroke and ischemic stroke. (nih.gov)
- Single-nucleotide polymorphisms at 17q25 were associated with WMHV in ischemic stroke, the most significant being rs9894383 (P=0.0006). (nih.gov)
- A genetic risk score analysis revealed further genetic components to WMHV shared between community participants without stroke and ischemic stroke. (nih.gov)
- 1 Large-vessel occlusion stroke, one of the most clinically devastating stroke subtypes, is believed to drive acute hospitalization costs in a disproportionate manner relative to other ischemic stroke etiologies. (ajnr.org)
- Association of statin pretreatment with collateral circulation and final infarct volume in acute ischemic stroke patients: A meta-analysis. (aace.com)
- Ischemic strokes were induced in 85 male Sprague-Dawley rats by occluding the middle cerebral artery for 3 hours using an intraluminal filament. (thejns.org)
- To examine the cost-effectiveness of warfarin sodium and aspirin for prophylaxis of stroke in patients with nonvalvular atrial fibrillation (NVAF), with or without additional risk factors for stroke (previous stroke or transient ischemic attack, diabetes, hypertension, or heart disease). (acpjc.org)
- Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. (acpjc.org)
- 3680 patients who were ≥ 35 years of age (mean age 66 y, 63% men) and had nondisabling ischemic stroke and elevated total homocysteine (tHcy) levels. (acpjc.org)
- Recurrent ischemic stroke and coronary heart disease (CHD) events (myocardial infarction [MI] requiring hospitalization, coronary revascularization, cardiac resuscitation, and fatal CHD). (acpjc.org)
- The high- and low-dose groups did not differ for recurrent ischemic stroke, CHD, or death (Table). (acpjc.org)
- The identification of the genes underlying these neuroprotective loci will provide new understanding of genetic risk factors of ischemic stroke which may provide novel targets for future therapeutic intervention of human ischemic stroke. (fondationleducq.org)
- Background Mechanical thrombectomy (MT) is a Level IA treatment in acute ischemic stroke (AIS) patients. (onlinejacc.org)
- Methods From the ETIS (Endovascular Treatment in Ischemic Stroke) study, a prospective, multicenter, observational real-world MT registry, the authors included all AIS patients consecutively treated by MT between January 2012 and March 2017 in 3 high-volume comprehensive stroke centers by 19 operators. (onlinejacc.org)
- We studied serum neurofilaments diagnostic value in patients with acute ischemic stroke (AIS) or TIA and evaluated any correlation with symptom severity, cerebral infarction volume, aetiology, and clinical outcome. (quanterix.com)
- Mokin M, Morr S, Fanous AA, Shallwani H, Natarajan SK, Levy EI, Snyder KV, Siddiqui AH: Correlation Between Cerebral Blood Volume Values and Outcomes in Endovascular Therapy for Acute Ischemic Stroke. (ubns.com)
- Leukoaraiosis Burden Significantly Modulates the Association Between Infarct Volume and National Institutes of Health Stroke Scale in Ischemic Stroke. (semanticscholar.org)
- BACKGROUND AND PURPOSE The National Institutes of Health Stroke Scale (NIHSS) provides a reliable, quantitative measure of ischemic stroke severity and is predicted by the infarct size. (semanticscholar.org)
- Integrity of normal-appearing white matter and functional outcomes after acute ischemic stroke. (semanticscholar.org)
- Clinical impact of leukoaraiosis burden and chronological age on neurological deficit recovery and 90-day outcome after minor ischemic stroke. (semanticscholar.org)
- A randomized trial of intraarterial treatment for acute ischemic stroke. (semanticscholar.org)
- Endovascular therapy for ischemic stroke with perfusion-imaging selection. (semanticscholar.org)
- Randomized assessment of rapid endovascular treatment of ischemic stroke. (semanticscholar.org)
- Extensive leukoaraiosis is associated with high early risk of recurrence after ischemic stroke. (semanticscholar.org)
- Khaksar S, Bigdeli M R. Correlation Between Cannabidiol-Induced Reduction of Infarct Volume and Inflammatory Factors Expression in Ischemic Stroke Model. (ac.ir)
- A consensus working group from numerous international societies has published new guidelines for standards of practice in the treatment of acute ischemic stroke (AIS). (mdedge.com)
Ejection fraction6
- Stroke volume is an important determinant of cardiac output, which is the product of stroke volume and heart rate, and is also used to calculate ejection fraction, which is stroke volume divided by end-diastolic volume. (wikipedia.org)
- Furthermore, to evaluate the possible involvement of an augmented ejection fraction on the increased stroke volume during digestion, we address whether the contractile properties in vitro and enzymatic properties of the ventricles are influenced by digestion. (biologists.org)
- Impaired function of the systemic RV has been inferred from the almost-uniform findings of increased RV volumes and decreased ejection fraction in midterm survivors. (ahajournals.org)
- 7 8 However, although one recent study showed a reduction in stroke volume in response to exercise and concluded that this implied ventricular dysfunction, 8 the few available data suggest that measurements of RV volumes and ejection fraction do not predict either functional performance or the likelihood of late deterioration. (ahajournals.org)
- Left ventricular (LV) volumes and ejection fraction (EF) are important predictors of cardiac morbidity and mortality. (diva-portal.org)
- So another helpful measurement is the ejection fraction, which is the stroke volume divided by the end-diastolic volume, Ejection fraction = Stroke Volume / End- Diastolic Volume. (osmosis.org)
Middle cerebral artery2
- To identify genes involved in cerebral infarction we have employed a forward genetic approach in inbred mouse strains, using quantitative trait locus (QTL) mapping for cerebral infarct volume after middle cerebral artery occlusion. (fondationleducq.org)
- Leukoaraiosis predicts cortical infarct volume after distal middle cerebral artery occlusion. (semanticscholar.org)
Variation16
- We previously identified a locus on distal mouse chromosome 7 that contributes over 50% of the variation in postischemic cerebral infarct volume observed between inbred strains. (jci.org)
- Predicting fluid responsiveness with stroke volume variation despite multiple extrasystoles. (biomedsearch.com)
- To investigate the ability of a new stroke volume variation algorithm to predict fluid responsiveness during general anesthesia and mechanical ventilation in animals with multiple extrasystoles. (biomedsearch.com)
- Arterial pressure waveforms were recorded and stroke volume variation was computed from the new and from the standard algorithm. (biomedsearch.com)
- The new stroke volume variation algorithm is designed to restore the respiratory component of the arterial pressure waveform despite multiple ectopic heart beats. (biomedsearch.com)
- 05), whereas the standard stroke volume variation algorithm was similar in the two groups (29% ± 8% vs. 26% ± 11%, p = .4). (biomedsearch.com)
- Receiver operating characteristic curve analysis showed that the new stroke volume variation algorithm was an accurate predictor of fluid responsiveness (sensitivity = 86%, specificity = 85%, best cutoff value = 14%, area under the curve = 0.892 ±, whereas the standard stroke volume variation was not (area under the curve = 0.596 ± 0.077). (biomedsearch.com)
- In contrast to the standard stroke volume variation, the new stroke volume variation algorithm was able to predict fluid responsiveness in animals with multiple ventricular extrasystoles. (biomedsearch.com)
- Nexfin beat-to-beat arterial blood pressure monitoring enables continuous assessment of hemodynamic indices like cardiac index (CI), pulse pressure variation (PPV) and stroke volume variation (SVV) in the perioperative setting. (springer.com)
- CO values measured using esCCO and APCO were collected every 6 h, and stroke volume variation (SVV) data were obtained every hour while patients were mechanically ventilated. (springer.com)
- Stroke volume variation assessed by a FlowTrac transducer and Vigileo monitor and PPV assessed by anaesthesia workstation-integrated monitors showed comparable performance in predicting fluid responsiveness in patients undergoing major surgeries. (thefreedictionary.com)
- In the present study, we aimed to evaluate whether stroke volume variation (SVV) can guide fluid therapy and reduce complications. (dovepress.com)
- 2 , 3 As a less invasive hemodynamic monitoring system based on arterial pulse contour analysis, stroke volume variation (SVV) allows continuous monitorization of the fluid status, and several studies have suggested that CVP can be reliably replaced by SVV in the management of fluid therapy. (dovepress.com)
- In this study, we expanded the pool of allelic variation among classical inbred mouse strains by utilizing the eight founder strains of the Collaborative Cross and found a wild-derived strain, WSB/EiJ, that breaks this general rule that collateral vessel density inversely correlates with infarct volume. (fondationleducq.org)
- Will stroke volume variation be a parameter to manage intraoperative bleeding in the functional endoscopic sinus surgery? (minervamedica.it)
- Kinoshita H, Kawahito S. Will stroke volume variation be a parameter to manage intraoperative bleeding in the functional endoscopic sinus surgery? (minervamedica.it)
METHODS9
- CONCLUSIONS: Both methods showed that a 10-mL change in stroke volume during follow-up should be considered as clinically relevant. (biomedsearch.com)
- Background and Purpose- Previous studies of cardiovascular risk factors and white matter hyperintensity (WMH) on brain MRI have been limited by the failure to exclude symptomatic cerebrovascular disease and dementia or by the use of semiquantitative rather than quantitative methods to measure WMH volume (WMHV). (ahajournals.org)
- Most large community-based MRI studies examining the relationship between cardiovascular risk factors and WMH have used semiquantitative methods to measure WMH volume (WMHV) on graded ordinal scales. (ahajournals.org)
- The current study examines the relationship between the Framingham Stroke Risk Profile (FSRP) and individual cardiovascular risk factors and WMHV in a community-based sample of individuals free of stroke and dementia using quantitative MRI methods. (ahajournals.org)
- Methods- BP measurements and volumes of whole-brain (WB), subcortical, and ependymal HWM lesions, measured from high-resolution (1 mm 3 ) 3-dimensional fluid-attenuated inversion recovery images, served as focal quantitative phenotypes. (ahajournals.org)
- PATIENTS AND METHODS Children with MCA territory infarcts were selected retrospectively from a database of children with ischaemic stroke. (bmj.com)
- Present methods for measurement of stroke volume from the aortic pressure pulse are not suitable for beat-to-beat determinations during non-steady state conditions because these methods assume that each systolic ejection is equal to the peripheral runoff during the same beat. (ahajournals.org)
- Aims: The aim of the study was to investigate whether left ventricular stroke volume (LVSV) assessment using direct measurement of left ventricular outflow tract area (LVOTA) is superior to conventional methods for SV calculation. (diva-portal.org)
- Methods - Data were obtained from 3 trials recruiting patients primarily with cortical stroke syndromes. (sinapse.ac.uk)
20203
- Accuracy of previous estimates for adult prolonged acute mechanical ventilation volume in 2020: Upda. (biomedsearch.com)
- It is estimated that direct medical costs for stroke treatment in the United States in 2015 reached $38 billion and will rise to $51.3 billion in 2020. (ajnr.org)
- Kiss Me at the Stroke of Midnight was serialized in the monthly manga magazine Bessatsu Friend from April 13, 2015 to May 13, 2020. (wikipedia.org)
Ischaemic stroke18
- Given that, anecdotally, the outcome after ischaemic stroke in childhood is thought to be good, many clinicians would hesitate before instituting potentially hazardous interventions in children. (bmj.com)
- If there is an association between lesion volume and outcome in children, knowledge of this would be useful in the management of children presenting with acute ischaemic stroke, specifically in targeting groups of children for therapeutic trials. (bmj.com)
- Huang, X. , Kalladka, D. , Cheripelli, B. K. , Moreton, F. C. and Muir, K. W. (2017) The impact of CT perfusion threshold on predicted viable and nonviable tissue volumes in acute ischaemic stroke. (gla.ac.uk)
- Concurrently, ischaemic stroke caused by nonvalvular atrial fibrillation (AF) has attracted increasing attention. (biomedcentral.com)
- The aim of this study was to investigate the association between MPV and the risk of ischaemic stroke in AF patients not receiving anticoagulant therapy. (biomedcentral.com)
- Patients were divided into a control group and a stroke group according to the presence of ischaemic stroke. (biomedcentral.com)
- MPV could be a new predictor of ischaemic stroke risk in patients with AF. (biomedcentral.com)
- Moreover, the CHA2D2S2-VASc combined with MPV can improve predictive value with higher sensitivity and it could be a powerful tool for stratifying patients in terms of ischaemic stroke risk. (biomedcentral.com)
- Accurate ischaemic stroke risk stratification in atrial fibrillation (AF) patients is an important aspect of AF management. (biomedcentral.com)
- The CHA2DS2-VASc (congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke or transient ischaemic stroke (TIA) or other embolic events, vascular disease, age 65 to 74 years, sex category) score is the most widely used AF-related ischaemic stroke risk stratification tool in the world today. (biomedcentral.com)
- We explored the risk factors of AF-related ischaemic stroke in the Chinese population and analysed the value of MPV, as well as the CHA2DS2-VASc score combined with MPV, in predicting AF-related ischaemic stroke risk to provide effective guidance for the prevention and management of AF-related ischaemic stroke. (biomedcentral.com)
- To study the prognostic importance activity of paraoxonase and arylesterase, and the value of mean platelet volume in patients with acute ischaemic stroke. (org.pk)
- This case-control study was conducted at Harran University Hospital, Sanliurfa, Turkey, from January to June 2014, and comprised patients with symptoms of acute ischaemic stroke who presented to the emergency department. (org.pk)
- Of the 94 participants, 48(51%) were patients with acute ischaemic stroke and 46(49%) were control subjects. (org.pk)
- Decreased paraoxonase and arylesterase activity and decreased platelet counts were observed probably due to increased oxidative stress in acute ischaemic stroke patients. (org.pk)
- Acute ischaemic stroke (AIS) is defined by a combined series of circumstances that develop over hours. (org.pk)
- 1,2 Moreover, oxidative damage can result in secondary brain injury in ischaemic stroke patients. (org.pk)
- 9 However, a few studies have specifically examined the platelet (PLT) indices associated with PON1 and arylesterase (ARES) in acute ischaemic stroke patients. (org.pk)
Increase in stroke volume5
- RESULTS: After 1 year of treatment, there was, on average, a significant increase in stroke volume and 6MWT. (biomedsearch.com)
- and (2) a subsequent increase in stroke volume presumably due to an inspiratory increase in right ventricular stroke volume. (ahajournals.org)
- This leads to an increase of left and right cardiac preload (autotransfusion), with later temporary increase in stroke volume (SV) and cardiac output. (thefreedictionary.com)
- This observation suggests that the lack of an increase in stroke volume during exercise is not due to the tuna heart operating at maximal anatomical limits. (biologists.org)
- An increase in stroke volume or cardiac output occurs when end-diastolic volume is increased (the Frank-Starling relation). (richardvigilantebooks.com)
Systolic16
- Stroke volume is calculated using measurements of ventricle volumes from an echocardiogram and subtracting the volume of the blood in the ventricle at the end of a beat (called end-systolic volume ) from the volume of blood just prior to the beat (called end-diastolic volume). (wikipedia.org)
- Its value is obtained by subtracting end-systolic volume (ESV) from end-diastolic volume (EDV) for a given ventricle. (wikipedia.org)
- 17 18 19 20 21 22 23 LV end-diastolic and end-systolic volumes were calculated with the Z -derived method, 24 which exhibited a high accuracy for M-mode LV volume calculation even in the presence of dilated LV cavities. (ahajournals.org)
- SV was calculated in milliliters per beat as end-diastolic minus end-systolic volume and normalized for body surface area (stroke index). (ahajournals.org)
- 5 The age-related decrease in stroke volume, by reducing pulse pressure, could explain the low proportion of systolic hypertension among middle-aged hypertensive individuals. (ahajournals.org)
- Results- Bivariate genomewide linkage analyses localized a significant quantitative trait locus influencing WB and regional (ependymal) HWM volumes and pulse pressure and systolic BP to chromosomal location 1q24 between markers D1S196 and D1S1619. (ahajournals.org)
- The stroke volume is determined by two parameters: the amount of blood in the ventricle before the contraction occurs (end diastolic volume) and the amount left at the end of contraction (end systolic volume). (thefreedictionary.com)
- A normal left ventricle must contract to eject an adequate stroke volume at a given arterial blood pressure (systolic function), and must fill back without requiring an abnormal increase in left atrial filling pressure (diastolic function)," Dr. (thefreedictionary.com)
- 1-6 The mechanism of low stroke volume (SV) has been attributed to reduced systemic arterial compliance (SAC), smaller LV cavity size due to concentric remodelling, restrictive physiology resulting in impaired LV filling and diminished LV systolic function despite preserved EF. (bmj.com)
- SV is the difference between end diastolic volume (EDV) and end systolic volume (ESV). (deltexmedical.com)
- The total systolic increment (delta PSV) is assumed to describe the pressure-volume characteristics during systole and is related to stroke volume by a constant multiplier that is derived from the indicator-dilution measurements of cardiac output. (ahajournals.org)
- Although total LV stroke volume is equal in healthy subjects and in clinically compensated heart failure patients with mild LV remodeling, the diastolic routes through the LV and pre-systolic energetics of the SV are significantly different in the two states. (springer.com)
- It can be readily calculated by subtracting the end-systolic volume from the end-diastolic volume. (richardvigilantebooks.com)
- For an average-sized man, the end-diastolic volume is 120 milliliters of blood and the end-systolic volume is 50 milliliters of blood. (richardvigilantebooks.com)
- 8cm systolic diameter, 22% FS, 117ml diastolic volume , 56.2 ml systolic volume , EF% 52, Stroke Volume 60.8, LVPW thickness .82cm, IVP thickness .88 So, my questions are the following: -Can you have some form of systolic dysfunction without ending up with an enlarged heart or an EF% lower than 50? (medhelp.org)
- So, end-diastolic volume minus end-systolic volume, gives us the stroke volume , which is the volume of blood that the left ventricle ejects with every heartbeat, or stroke. (osmosis.org)
Clinical15
- Clinical genetic issues in stroke. (elsevier.com)
- Advances in our understanding of the biochemical background of strokes, coupled with an examination of breakthroughs in epidemiology, genetics, neuroimaging, interventional radiology, surgery, and even clinical psychology are also explored, giving researchers and clinicians a profoundly altered way to approach stroke research, diagnosis, and patient treatment and care. (elsevier.com)
- This value can be used to interpret changes in stroke volume during clinical follow-up in PH. (biomedsearch.com)
- Acute stroke therapies that reduce final infarct volume may not only improve clinical outcomes but may also prove cost-effective. (ajnr.org)
- In patients with acute stroke who were last known to be well 6 to 24 hours earlier and had a mismatch between clinical deficit and infarction, what are the efficacy and safety of thrombectomy? (annals.org)
- Randomized controlled trial (DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo [DAWN] trial). (annals.org)
- The aim of our study was to assess the correlation between initial cerebral infarct (CI) volume (quantified on diffusion-weighted MRI) and the resulting clinical outcome in acute stroke patients with middle cerebral artery (MCA) (M(1-2) segment) occlusion detected on MRI angiography treated by intravenous/intraarterial thrombolysis. (nih.gov)
- Initial infarct volume (V(DWI-I) ) was retrospectively compared with neurological deficit evaluated using the NIH stroke scale on admission and 24 h later, and with the 90-day clinical outcome assessed using the modified Rankin scale in a series of 25 consecutive CI patients. (nih.gov)
- Clinical outcome could be predicted from initial infarct volume quantified by MRI-DWI in acute CI patients with MCA occlusion treated by intravenous/intraarterial thrombolysis. (nih.gov)
- AIM To investigate the relation between lesion volume, lesion location, and clinical outcome in children with infarction in the territory of the middle cerebral artery (MCA). (bmj.com)
- 2 Saunders and colleagues 3 showed recently that measurement of infarct volume on T2 weighted magnetic resonance imaging (MRI) scans taken within 72 hours of stroke predicted clinical outcome in a group of adults with cortical MCA territory infarction. (bmj.com)
- This study lends formal support to the clinical strategy of anticoagulating patients who are aged 65 to 74 years and are at medium to high risk for stroke. (acpjc.org)
- 30 patients (63% women) who had clinical evidence of a severe stroke and dysphagia and who were unconscious at hospital admission. (acpjc.org)
- At this time, it is difficult to establish an evidence-based clinical policy for feeding patients with dysphagia after stroke. (acpjc.org)
- The VISP trial is the first large RCT evaluating the effect of folic-acid-based multivitamin therapy on such "hard" clinical outcomes as stroke. (acpjc.org)
CONCLUSIONS5
- Conclusions- FSRP and several cardiovascular risk factors were related to both WMHV measured continuously and to a categorical designation of large volumes of WMH. (ahajournals.org)
- Conclusions -The stroke volume response to exercise stress is reduced in patients after the Mustard operation. (ahajournals.org)
- CONCLUSIONS Although the outcome after a small infarct in the MCA territory is variable and unpredictable, infarction of more than 10% of intracranial volume is universally associated with a poor outcome. (bmj.com)
- Conclusions: SV and CO calculations using direct measurement of LVOT area is a feasible, accurate and reproducible method and correlates extremely well with 3DE volume measurements. (diva-portal.org)
- Conclusions - Patients with acute stroke who retain capacity to consent have significantly smaller infarct volumes than those incapable of consent, and these are frequently below the limits where measurement error significantly compromises valid use of volumetric end points. (sinapse.ac.uk)
Outcomes4
- Therefore, health outcomes of stroke treatment vary throughout the world. (eurekaselect.com)
- See Stroke Volume Optimisation and Improved Outcomes . (deltexmedical.com)
- Now researchers at Emory University School of Medicine say stroke patients cared for at high volume centers receive faster treatment and fair better with overall outcomes than stroke centers dealing with a lower volume of cases. (emory.edu)
- This translates to healthier stroke outcomes and better chances of improved functional recovery. (emory.edu)
Diastolic volume9
- Reduced heart rate prolongs ventricular diastole (filling), increasing end-diastolic volume, and ultimately allowing more blood to be ejected. (wikipedia.org)
- leaving little capacity for further reductions in end-diastolic volume. (biologists.org)
- quantitatively, the diastolic volume of the left ventricle minus the volume of blood in the ventricle at the end of systole. (thefreedictionary.com)
- What is normal end diastolic volume? (richardvigilantebooks.com)
- What happens when end diastolic volume increases? (richardvigilantebooks.com)
- At all ages, ventricular output depends on end-diastolic volume. (richardvigilantebooks.com)
- How do you reduce end diastolic volume? (richardvigilantebooks.com)
- The volume of blood in the left ventricle at the end of ventricular filling is called the end-diastolic volume (EDV), which is about 120 mL in the adult human. (richardvigilantebooks.com)
- It occurs at the end of filling or diastole, also called the end-diastolic point, and the volume of blood within the left ventricle is called the end-diastolic volume, and it's about 120 milliliters. (osmosis.org)
Right ventricular stroke volume2
- The effect of reducing the force of right atrial contraction on right ventricular stroke volume was determined in anesthetized open-chest dogs. (ahajournals.org)
- right ventricular stroke volume was measured with an electro-magnetic flowmeter. (ahajournals.org)
Occlusion6
- Anterior circulation large-vessel occlusion stroke, one of the most devastating stroke subtypes, is associated with substantial economic burden. (ajnr.org)
- We aimed to identify predictors of increased acute care hospitalization costs associated with anterior circulation large-vessel occlusion stroke. (ajnr.org)
- Comprehensive cost-tracking software was used to calculate acute care hospitalization costs for patients with anterior circulation large-vessel occlusion stroke admitted July 2012 to October 2014. (ajnr.org)
- Final infarct volume was the strongest predictor of increased hospitalization costs in anterior circulation large-vessel occlusion stroke. (ajnr.org)
- Pittsburgh Response to Endovascular therapy (PRE) score: optimizing patient selection for endovascular therapy for large vessel occlusion strokes. (semanticscholar.org)
- The publication in 2015 of studies showing the efficacy of MT in anterior circulation emergent large-vessel occlusion (ELVO) stroke patients reverberated through the stroke care community, but posed a challenge in delivering this therapy to populations in diverse localities that have no access to level 1 stroke centers. (mdedge.com)
Outcome3
- Although there was no significant effect of lesion size or lesion location on outcome for the group as a whole, all children who had infarcted more than 10% of intracranial volume had a poor outcome. (bmj.com)
- 001) and mRS scores after 3 months (r = .306, P = .004) correlated with sNfL concentration, however functional outcome 3 months after stroke was not associated with sNfL after adjusting for potential confounders. (quanterix.com)
- Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes. (semanticscholar.org)
Arterial pressure4
- 1. Simultaneous recordings of beat-to-beat left cardiac stroke volume (SV, pulsed ultrasound Doppler), mean arterial pressure (MAP) and heart rate (HR) were obtained in ten healthy young adults during spontaneous respiration at supine rest, before and after cholinergic blockade by atropine (0.035 mg kg-1). (nih.gov)
- Slopes (pooled across groups) relating heart rate (.3 bpm/mmHg ), mean arterial pressure (-.16 mmHg/mmHg), and stroke volume (-1.3 ml/mmHg) to the level of LBNP applied were not dependent on decompression rate (all ANOVA comparisons, p ≥ .3). (wku.edu)
- In conclusion, we believe that dynamic Ea predicting arterial pressure response to volume loading in preload-dependent patients is an interesting physiological concept. (biomedcentral.com)
- Dynamic arterial elastance to predict arterial pressure response to volume loading in preload-dependent patients. (biomedcentral.com)
Department of Neurology1
- Fernando Pico, Department of Neurology and Stroke Center, Centre Hospitalier de Versailles, 177 Rue de Versailles, Versailles Saint-Quentin en Yvelines et Paris Saclay University, 78150 Le Chesnay, Versailles, France. (onlinejacc.org)
Abstract1
- Abstract -Ratio of stroke volume (SV, M-mode echocardiography) to pulse pressure (PP) has been proposed as an estimate of total arterial compliance and has been shown to be related to body size, age, and heart rate in normal adults. (ahajournals.org)
Patients with nonvalvular atrial fibrillation1
- Cost-effectiveness of warfarin and aspirin for prophylaxis of stroke in patients with nonvalvular atrial fibrillation. (acpjc.org)
Left ventricular7
- Ernesto Goldman, "A Model Simulation for Decreased Left Ventricular Stroke Volume in Obstructive Sleep-Disordered Breathing," ISRN Pulmonology , vol. 2012, Article ID 926345, 5 pages, 2012. (hindawi.com)
- These results are consistent with a reduction in left ventricular filling during inspiration as the factor primarily responsible for the fall in stroke volume. (ahajournals.org)
- Measurements included the stroke volume and Left ventricular end-diastolic diameter. (thefreedictionary.com)
- Although total left ventricular (LV) stroke volume (SV) is equal in healthy subjects and heart failure patients with mild LV remodeling, the SV's transventricular flow paths to ejection and diastolic energetics are different. (springer.com)
- In earlier stages of heart failure with adaptive remodeling, patients may remain clinically compensated and the failing heart's left ventricular (LV) stroke volume (SV) remains the same as in the normal heart. (springer.com)
- Pathline visualization at end-diastole of left ventricular Total stroke volume (SV) separated into Direct SV (green color) and Delayed SV (blue color), respectively. (springer.com)
- Left ventricular Direct stroke volume / Total stroke volume -ratios for volume (left) and kinetic energy (KE) at end-diastole (ED) (right). (springer.com)
Centers12
- Centers that perform a large number of endovascular stroke therapies are more efficient and better at it," says Rishi Gupta, MD, associate professor of neurology at Emory University School of Medicine. (emory.edu)
- Gupta sees patients at the Marcus Stroke and Neuroscience Center at Grady Memorial Hospital - one of the leading centers in the country at rapid treatment and restoration of blood flow to the brain for acute stroke. (emory.edu)
- This study highlights the importance of patients coming to the hospital quickly with stroke symptoms and centers being quick at achieving restoration of blood flow (reperfusion) as is done with myocardial infarction," says Gupta. (emory.edu)
- Researcher defined stroke centers as high volume if more than 50 such procedures are carried out a year. (emory.edu)
- The results of the study are based on the findings from 442 patients treated with endovascular therapy involving clot-busting treatment provided inside the brain via a catheter without the need for surgery at nine stroke centers between September 2009 and July 2011. (emory.edu)
- the remaining 20 percent were treated at low volume centers. (emory.edu)
- Patients treated at high volume stroke centers were 86 percent more likely to survive and 82 percent more likely to have blood flow successfully restored in the affected artery. (emory.edu)
- The new guidelines differ somewhat from the Joint Commission guideline, released in 2015, primarily by raising the bar for the number of mechanical thrombectomy (MT) procedures that level 1 and level 2 stroke centers should perform annually in order to maintain a minimum safety threshold. (mdedge.com)
- Previous studies have shown lower mortality in high-volume centers, but setting minimum standards can be a challenge, especially in under-served countries and localities. (mdedge.com)
- The authors, led by first author Laurent Pierot, MD, PhD , of University Hospital Reims (France), acknowledge that newly established level 2 centers may struggle to meet the minimum requirement for MT procedures, but that this is acceptable as long as the volume is expected to meet the minimum within 12-24 months. (mdedge.com)
- In highly developed countries, stroke centers should follow regional or national guidelines that have higher limits. (mdedge.com)
- TJC offered no minimum annual procedures for Comprehensive Stroke Centers (equivalent to level 1), and only 15 for Thrombectomy Capable Stroke Centers (level 2), versus 50 in the new guidelines. (mdedge.com)
Pulmonary4
- Clinically significant change in stroke volume in pulmonary hypertension. (biomedsearch.com)
- BACKGROUND: Stroke volume is probably the best hemodynamic parameter because it reflects therapeutic changes and contains prognostic information in pulmonary hypertension (PH). (biomedsearch.com)
- Our goal is to estimate the impact of this variability on the EIT-based monitoring of two important central hemodynamic parameters: stroke volume (SV) and pulmonary artery pressure (PAP). (csem.ch)
- However, one of the drawbacks of TEE compared to pulmonary artery catheters is the inability to measure real time stroke volume (SV) and cardiac output (CO) continuously. (elsevier.com)
Measurements8
- Currently, there is no noninvasive method available for simultaneous measurements of tidal volume and stroke volume. (nature.com)
- The results show the feasibility of the proposed method as a new noninvasive cardiopulmonary monitoring tool for simultaneous continuous measurements of stroke volume and tidal volume that are two most important vital signs. (nature.com)
- Simultaneous measurements of stroke volume and tidal volume will enable monitoring of cardiopulmonary functions in an integrated way. (nature.com)
- We performed bivariate, whole-genome linkage analyses for HWM volumes and BP measurements to identify chromosomal regions that contribute jointly to both traits in a population of healthy Mexican Americans. (ahajournals.org)
- Our aims were to localize novel quantitative trait loci acting pleiotropically on these phenotypes and to replicate previous genetic findings on whole brain HWM volume and BP measurements. (ahajournals.org)
- Recent findings by Turner and colleagues 4 have identified overlap between genetic loci for the whole-brain (WB) HWM volume and blood pressure (BP) measurements in 488 hypertensive sibships. (ahajournals.org)
- In the current article, we pursued to replicate findings by Turner and colleagues 4 using bivariate linkage analysis for WB HWM volume and BP measurements. (ahajournals.org)
- Blood flow measurements revealed a mean increase in relative cardiac output of 13.6 +/- 3.0% with exercise (mean velocities 1.23-2.10 FLs-1) caused by an 18.8 +/- 5.4% increase in fH and a 3.9 +/- 2.3% decrease in stroke volume. (biologists.org)
Cerebrovascular3
- The history of stroke and cerebrovascular disease. (elsevier.com)
- With the field of cerebrovascular disorders, including stroke, making rapid advancements, clinicians will find illuminating and insightful chapters on the pathophysiological basis of this disorder. (elsevier.com)
- Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. (quanterix.com)
Decrease in stroke volume1
- In 7 of 10 experiments, increasing the inhibition of atrial force produced a further decrease in stroke volume. (ahajournals.org)
NIHSS3
- Final infarct volume, parenchymal hematoma, baseline NIHSS score, ipsilateral carotid stenosis, age, and obstructive sleep apnea were significant predictors of acute care hospitalization costs. (ajnr.org)
- Logistic regression demonstrated NIHSS or lesion volume predicted capacity to consent. (sinapse.ac.uk)
- Stroke aetiology was defined by trial of ORG 10172 in acute stroke treatment classification, severity by National Institute of Health stroke scale (NIHSS) and the degree of disability by the Modified Rankin Scale (mRS) after 90 days. (quanterix.com)
Increases4
- 2-5 Increases in HWM volume are correlated with a decline in cerebral blood flow, 6 glucose metabolism, 7 and cognition. (ahajournals.org)
- Acute reductions in ambient temperature at slow swimming velocities resulted in decreases in cardiac output (Q10 = 1.52) and fH (Q10 = 2.16), but increases in stroke volume (Q10 = 0.78). (biologists.org)
- So a parameter that increases volume will increase blood flow and the stroke volume is increased with an increase in contractility. (medhelp.org)
- The only way I know of to lower resting heartrate is to strengthen your heart through exercise (it improves the efficiency of your muscles including the heart and also increases the stroke volume of the heart so that you pump more blood with every beat) but I don't know how issues like age, heart disease etc affect that process. (medhelp.org)
Prognosis3
- Stroke recurrence and prognosis after stroke. (elsevier.com)
- Objective Low-gradient (LG) severe aortic stenosis (AS) and preserved EF with reduced stroke volume are associated with an adverse prognosis, but the relationship of stroke volume index (SVI) with mortality among a range of values is unknown. (bmj.com)
- Finally, some studies have reported that children with a pre-existing medical condition ("symptomatic" stroke) have a worse prognosis than those with apparently "idiopathic" stroke. (bmj.com)
Atrial3
- In this issue expert authors review drug therapies for stroke prevention, use of the new anticoagulants, ablation strategies for stroke prevention, LAA closure for stroke prevention, stroke in heart rhythm device patients, transesophageal echo in atrial fibrillation, and other topics important to the management of this serious complication. (elsevier.com)
- The relation between the decrease in atrial force and stroke volume was not altered significantly by the rate of right atrial pacing. (ahajournals.org)
- Warfarin therapy was cost-effective for prophylaxis of stroke in patients aged 65 years who had nonvalvular atrial fibrillation and at least 1 additional risk factor for stroke. (acpjc.org)
Vessel10
- White matter hyperintensity volume is increased in small vessel stroke subtypes. (nih.gov)
- Therefore, we hypothesized that WMH would be most severe in patients with lacunar stroke and intracerebral hemorrhage (ICH), 2 types of stroke in which cerebral small vessel (SV) changes are pathophysiologically relevant. (nih.gov)
- Small vessel stroke and white matter lesions: peas in a pod, or horses of a different color? (nih.gov)
- Collateral vessel connections were moderately reduced in Il21r -deficient mice, and cerebral infarct volume increased 2.3-fold, suggesting that Il21r modulates both collateral vessel anatomy and innate neuroprotection. (jci.org)
- If the association acts by promoting a small vessel arteriopathy, it might be expected to also associate with lacunar stroke. (nih.gov)
- In contrast, it is not associated with lacunar stroke, suggesting that the association does not act by promoting small-vessel arteriopathy or the same arteriopathy responsible for lacunar infarction. (nih.gov)
- We had previously observed that infarct volume is inversely correlated with cerebral collateral vessel density in most strains. (fondationleducq.org)
- WSB/EiJ and another wild-derived strain, CAST/EiJ, show the highest collateral vessel densities of any inbred strain, but infarct volume of WSB/EiJ mice is 8.7-fold larger than that of CAST/EiJ mice. (fondationleducq.org)
- QTL mapping between these strains identified four new neuroprotective loci modulating cerebral infarct volume while not affecting collateral vessel phenotypes. (fondationleducq.org)
- A stroke occurs when the blood supply to part of the brain is blocked or when a blood vessel in the brain bursts. (emory.edu)
Increased vascular1
- There was no rise in blood volume and the elevated MCFP must therefore stem from increased vascular tone, possibly by means of increased sympathetic tone on the veins. (biologists.org)
Correlates1
- Because stroke volume decreases in certain conditions and disease states, stroke volume itself correlates with cardiac function. (wikipedia.org)
Reduction in stroke2
- Decreased venous return has the opposite effect, causing a reduction in stroke volume. (wikipedia.org)
- A promising reduction in stroke volumes is seen. (uwo.ca)
Endovascular Therapy1
- Patient selection for stroke endovascular therapy--DWI-ASPECTS thresholds should vary among age groups: insights from the RECOST study. (semanticscholar.org)
Final infarct volume3
- Patient demographics and stroke characteristics were analyzed, including final infarct volume on follow-up neuroimaging. (ajnr.org)
- Final infarct volume alone accounted for 20.87% of the total cost variance. (ajnr.org)
- Additionally, final infarct volume was consistently the strongest predictor of increased cost in primary, subgroup, and sensitivity analyses. (ajnr.org)
Reduces infarct volume1
- Intranasal administration of TGF-β1 reduces infarct volume, improves functional recovery and enhances neurogenesis in mice after stroke. (biomedcentral.com)
Thrombosis1
- Mean platelet volume (MPV) has been identified as an individual risk factor for stroke and thrombosis. (biomedcentral.com)
Infarct volumes1
- The modified Neurological Severity Scores (NSS) test was used to evaluate neurological function, and infarct volumes were determined from hematoxylin-stained sections. (biomedcentral.com)
Recurrence1
- In patients with nondisabling cerebral infarction, do high doses of a homocysteine-lowering regimen of pyridoxine, cobalamin, and folic acid prevent stroke recurrence better than low doses of this regimen? (acpjc.org)
Significantly4
- Thus, in hypertensive men, the age-related change in stroke volume significantly accounted for the change in clinic and ambulatory pulse pressure during young adulthood, but its contribution decreased after the fifth decade. (ahajournals.org)
- Ovation BioNatural Single-Channel Pipettors One-Stroke Operation, Fixed Volume, VistaLab : Revolutionary ergonomic design addresses the issues of posture, repetition, and force to significantly reduce strain and pain that occur from pipetting. (egeneralmedical.com)
- The volume of penumbra salvaged at 24 hours (30 ± 19 mL vs. 35 ± 26 mL, P = .043) differed significantly, although the percentages of penumbra salvaged did not (P= .2). (gla.ac.uk)
- Conclusion: Two commonly used tissue definitions generated significantly different lesion volumes and mismatch ratios. (gla.ac.uk)
Respiration1
- Influence of respiration on stroke volume determined by impedance cardiography. (semanticscholar.org)
Reperfusion2
- Reperfusion injury after stroke: neurovascular proteases and the blood-brain barrier. (elsevier.com)
- After 24 h reperfusion, the infarct volume in total, cortex, piriform cortex-amygdala (Pir-Amy), and striatum areas of hemisphere were assessed. (ac.ir)
Measurement4
- Continuous measurement of cardiac output (CO), stroke volume (SV) and/or systemic vascular resistance (SVR) changes. (clinicaltrials.gov)
- The values for beat-to-beat variations that were determined by use of the aortic electromagnetic flowmeter and by this aortic pressure pulse method were found to be within the range of measurement errors of stroke volume determined from individual aortic electromagnetic flow pulses. (ahajournals.org)
- For a more definitive measurement a right heart catheterization is necessary because the exercise echocardiogram has limitations, namely the inability to measure left-sided filling pressures and cardiac output ( stroke volume ) that is in part needed for evaluation. (medhelp.org)
- Stroke volume is a useful measurement, but it can vary based on the size of a person. (osmosis.org)
Cardiac index2
- citation needed] Similar to cardiac index, stroke volume index is a method of relating the stroke volume (SV) to the size of the person Body surface area (BSA). (wikipedia.org)
- Both exercise and dobutamine infusion were associated with an increase in cardiac index and heart rate and a reduced stroke volume index response. (ahajournals.org)
Therapies1
- Results from this study are potentially practice-changing, informing and guiding post-stroke investigations and therapies. (heartfoundation.org.au)
Thrombotic1
- Also, increased platelet volume has more active and higher thrombotic potency. (org.pk)
Lesion volumes3
- We compared brain lesion volumes in stroke patients deemed to have capacity to consent with those defined as incapacitated. (sinapse.ac.uk)
- Method of recruitment was recorded with stroke severity, age, and brain lesion volumes on Diffusion Weighted Imaging. (sinapse.ac.uk)
- We compared the lesion volumes generated with two well-recognized perfusion tissue definitions in a single-center phase 2 thrombolysis study. (gla.ac.uk)
Vascular Resistance3
- Pregnant patients having a cesarean section (CS) under spinal anesthesia experience a variety of hemodynamic changes, such as hypotension due to decreases in cardiac output (CO), stroke volume (SV) and/or systemic vascular resistance (SVR). (clinicaltrials.gov)
- The etiology of hypotension is multi-factorial,and it is postulated that decreases in cardiac output (CO), stroke volume (SV) and/or systemic vascular resistance (SVR) may precede decreases in blood pressure. (clinicaltrials.gov)
- Afterload, also known as the systemic vascular resistance (SVR), is the amount of resistance the heart must overcome to open the aortic valve and push the blood volume out into the systemic circulation. (richardvigilantebooks.com)
Infarction4
- In patients with nondisabling cerebral infarction, a multivitamin tablet with high doses of pyridoxine, cobalamin, and folic acid did not differ from a low-dose tablet for reducing recurrent stroke. (acpjc.org)
- The presence and amount of axonal damage estimated by sNfL correlated with the final cerebral infarction volume but was not predictive of degree of disability. (quanterix.com)
- The aim of the present study was to evaluate the effect of cannabidiol on infarction volume and correlation of infarct size with tumor necrosis factor receptor 1 (TNFR1), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) expression. (ac.ir)
- The present results indicate that in the MCAO-induced cerebral ischemia, administration of cannabidiol (100 and 200 ng) causes a significant reduction in infarction volume in comparison with the vehicle group. (ac.ir)
Hemodynamic1
- For this reason, stroke volume, which can be measured noninvasively, is an important hemodynamic parameter to monitor during treatment. (biomedsearch.com)
Systole3
- citation needed] Elevated afterload (commonly measured as the aortic pressure during systole) reduces stroke volume. (wikipedia.org)
- S V I = S V B S A = ( C O / H R ) B S A = C O H R × B S A {\displaystyle SVI={SV \over BSA}={(CO/HR) \over BSA}={CO \over {HR\times BSA}}} In short, the remaining blood volume left in the left ventricle not pumped out after a systole. (wikipedia.org)
- The greater the muscle stretch, the more powerful the contraction during systole and the bigger the volume of blood pumped to the rest of the body. (reference.com)
Preload3
- citation needed] Stroke volume is intrinsically controlled by preload (the degree to which the ventricles are stretched prior to contracting). (wikipedia.org)
- An increase in the volume or speed of venous return will increase preload and, through the Frank-Starling law of the heart, will increase stroke volume. (wikipedia.org)
- Stroke volume is affected by preload and afterload, according to Cheetah Medical. (reference.com)