An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
The behaviors of materials under force.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
The properties and processes of materials that affect their behavior under force.
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
Resistance and recovery from distortion of shape.
Act of eliciting a response from a person or organism through physical contact.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
Numerical expression indicating the measure of stiffness in a material. It is defined by the ratio of stress in a unit area of substance to the resulting deformation (strain). This allows the behavior of a material under load (such as bone) to be calculated.
Mechanical devices used to produce or assist pulmonary ventilation.

Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis. (1/9460)

Insulin-like growth factor (IGF)-1 inhibits apoptosis, but its mechanism is unknown. Myocyte stretching activates p53 and p53-dependent genes, leading to the formation of angiotensin II (Ang II) and apoptosis. Therefore, this in vitro system was used to determine whether IGF-1 interfered with p53 function and the local renin-angiotensin system (RAS), decreasing stretch-induced cell death. A single dose of 200 ng/ml IGF-1 at the time of stretching decreased myocyte apoptosis 43% and 61% at 6 and 20 hours. Ang II concentration was reduced 52% at 20 hours. Additionally, p53 DNA binding to angiotensinogen (Aogen), AT1 receptor, and Bax was markedly down-regulated by IGF-1 via the induction of Mdm2 and the formation of Mdm2-p53 complexes. Concurrently, the quantity of p53, Aogen, renin, AT1 receptor, and Bax was reduced in stretched myocytes exposed to IGF-1. Conversely, Bcl-2 and the Bcl-2-to-Bax protein ratio increased. The effects of IGF-1 on cell death, Ang II synthesis, and Bax protein were the consequence of Mdm2-induced down-regulation of p53 function. In conclusion, the anti-apoptotic impact of IGF-1 on stretched myocytes was mediated by its capacity to depress p53 transcriptional activity, which limited Ang II formation and attenuated the susceptibility of myocytes to trigger their endogenous cell death pathway.  (+info)

Fibrocartilage in tendons and ligaments--an adaptation to compressive load. (2/9460)

Where tendons and ligaments are subject to compression, they are frequently fibrocartilaginous. This occurs at 2 principal sites: where tendons (and sometimes ligaments) wrap around bony or fibrous pulleys, and in the region where they attach to bone, i.e. at their entheses. Wrap-around tendons are most characteristic of the limbs and are commonly wider at their point of bony contact so that the pressure is reduced. The most fibrocartilaginous tendons are heavily loaded and permanently bent around their pulleys. There is often pronounced interweaving of collagen fibres that prevents the tendons from splaying apart under compression. The fibrocartilage can be located within fascicles, or in endo- or epitenon (where it may protect blood vessels from compression or allow fascicles to slide). Fibrocartilage cells are commonly packed with intermediate filaments which could be involved in transducing mechanical load. The ECM often contains aggrecan which allows the tendon to imbibe water and withstand compression. Type II collagen may also be present, particularly in tendons that are heavily loaded. Fibrocartilage is a dynamic tissue that disappears when the tendons are rerouted surgically and can be maintained in vitro when discs of tendon are compressed. Finite element analyses provide a good correlation between its distribution and levels of compressive stress, but at some locations fibrocartilage is a sign of pathology. Enthesis fibrocartilage is most typical of tendons or ligaments that attach to the epiphyses of long bones where it may also be accompanied by sesamoid and periosteal fibrocartilages. It is characteristic of sites where the angle of attachment changes throughout the range of joint movement and it reduces wear and tear by dissipating stress concentration at the bony interface. There is a good correlation between the distribution of fibrocartilage within an enthesis and the levels of compressive stress. The complex interlocking between calcified fibrocartilage and bone contributes to the mechanical strength of the enthesis and cartilage-like molecules (e.g. aggrecan and type II collagen) in the ECM contribute to its ability to withstand compression. Pathological changes are common and are known as enthesopathies.  (+info)

Receptor mechanisms underlying heterogenic reflexes among the triceps surae muscles of the cat. (3/9460)

The soleus (S), medial gastrocnemius (MG), and lateral gastrocnemius (LG) muscles of the cat are interlinked by rapid spinal reflex pathways. In the decerebrate state, these heterogenic reflexes are either excitatory and length dependent or inhibitory and force dependent. Mechanographic analysis was used to obtain additional evidence that the muscle spindle primary ending and the Golgi tendon organ provide the major contributions to these reflexes, respectively. The tendons of the triceps surae muscles were separated and connected to independent force transducers and servo-controlled torque motors in unanesthetized, decerebrate cats. The muscles were activated as a group using crossed-extension reflexes. Electrical stimulation of the caudal cutaneous sural nerve was used to provide a particularly strong activation of MG and decouple the forces of the triceps surae muscles. During either form of activation, the muscles were stretched either individually or in various combinations to determine the strength and characteristics of autogenic and heterogenic feedback. The corresponding force responses, including both active and passive components, were measured during the changing background tension. During activation of the entire group, the excitatory, heterogenic feedback linking the three muscles was found to be strongest onto LG and weakest onto MG, in agreement with previous results concerning the strengths of heteronymous Ia excitatory postsynaptic potentials among the triceps surae muscles. The inhibition, which is known to affect only the soleus muscle, was dependent on active contractile force and was detected essentially as rapidly as length dependent excitation. The inhibition outlasted the excitation and was blocked by intravenous strychnine. These results indicate that the excitatory and inhibitory effects are dominated by feedback from primary spindle receptors and Golgi tendon organs. The interactions between these two feedback pathways potentially can influence both the mechanical coupling between ankle and knee.  (+info)

Glycoprotein (GP) Ib-IX-transfected cells roll on a von Willebrand factor matrix under flow. Importance of the GPib/actin-binding protein (ABP-280) interaction in maintaining adhesion under high shear. (4/9460)

Adhesion of platelets to sites of vascular injury is critical for hemostasis and thrombosis and is dependent on the binding of the vascular adhesive protein von Willebrand factor (vWf) to the glycoprotein (GP) Ib-V-IX complex on the platelet surface. A unique but poorly defined characteristic of this receptor/ligand interaction is its ability to support platelet adhesion under conditions of high shear stress. To examine the structural domains of the GPIb-V-IX complex involved in mediating cell adhesion under flow, we have expressed partial (GPIb-IX), complete (GPIb-V-IX), and mutant (GPIbalpha cytoplasmic tail mutants) receptor complexes on the surface of Chinese hamster ovary (CHO) cells and examined their ability to adhere to a vWf matrix in flow-based adhesion assays. Our studies demonstrate that the partial receptor complex (GPIb-IX) supports CHO cell tethering and rolling on a bovine or human vWf matrix under flow. The adhesion was specifically inhibited by an anti-GPIbalpha blocking antibody (AK2) and was not observed with CHO cells expressing GPIbbeta and GPIX alone. The velocity of rolling was dependent on the level of shear stress, receptor density, and matrix concentration and was not altered by the presence of GPV. In contrast to selectins, which mediate cell rolling under conditions of low shear (20-200 s-1), GPIb-IX was able to support cell rolling at both venous (150 s-1) and arterial (1500-10,500 s-1) shear rates. Studies with a mutant GPIbalpha receptor subunit lacking the binding domain for actin-binding protein demonstrated that the association of the receptor complex with the membrane skeleton is not essential for cell tethering or rolling under low shear conditions, but is critical for maintaining adhesion at high shear rates (3000-6000 s-1). These studies demonstrate that the GPIb-IX complex is sufficient to mediate cell rolling on a vWf matrix at both venous and arterial levels of shear independent of other platelet adhesion receptors. Furthermore, our results suggest that the association between GPIbalpha and actin-binding protein plays an important role in enabling cells to remain tethered to a vWf matrix under conditions of high shear stress.  (+info)

Cloning of a stretch-inhibitable nonselective cation channel. (5/9460)

A homologue of the capsaicin receptor-nonselective cation channel was cloned from the rat kidney to investigate a mechanosensitive channel. We found this channel to be inactivated by membrane stretch and have designated it stretch-inactivated channel (SIC). SIC encodes a 563-amino acid protein with putative six transmembrane segments. The cDNA was expressed in mammalian cells, and electophysiological studies were performed. SIC-induced large cation currents were found to be regulated by cell volume, with currents being stimulated by cell shrinkage and inhibited by cell swelling. Single channel analysis showed a conductance of 250 pS with cation permeability (PCl/PNa < 0.1), and the channel possessed some of the characteristics of a stretch-inactivated channel in that it was permeable to calcium, sensitive to membrane stretch, and blocked by Gd3+. Therefore, we cloned one of the mechanosensitive cation channels of mammals, which is considered to regulate Ca2+ influx in response to mechanical stress on the cell membrane.  (+info)

Distinct structural attributes regulating von Willebrand factor A1 domain interaction with platelet glycoprotein Ibalpha under flow. (6/9460)

We have used recombinant von Willebrand factor (vWF) fragments to investigate the properties regulating A1 domain interaction with platelet glycoprotein (GP) Ibalpha. One fragment, rvWF508-704, represented the main portion of domain A1 (mature subunit residues 497-716) within the Cys509-Cys695 disulfide loop. The other, rvWF445-733, included the carboxyl-terminal region of domain D3, preceding A1, and corresponded to the proteolytic fragment originally identified as the GP Ibalpha-binding site (residues 449-728). Conformational changes were induced by reduction and alkylation of the Cys509-Cys695 bond and/or exposure to acidic pH. The cyclic rvWF445-733 fragment exhibited the function of native vWF A1 domain. When immobilized onto a surface, it tethered platelets at shear rates up to 6,300 s-1 mediating low velocity translocation but not stable attachment; in solution, it exhibited limited interaction with GP Ibalpha. In contrast, fragments with perturbed conformation could not tether platelets at high shear rates but promoted stable adhesion at lower shear and bound tightly to GP Ibalpha. Only in the presence of the exogenous modulator, botrocetin, did cyclic rvWF445-733 mediate irreversible adhesion. Thus, conformational transitions in the vWF A1 domain may influence differentially the efficiency of bond formation with GP Ibalpha and the stability of binding.  (+info)

Calculation of a Gap restoration in the membrane skeleton of the red blood cell: possible role for myosin II in local repair. (7/9460)

Human red blood cells contain all of the elements involved in the formation of nonmuscle actomyosin II complexes (V. M. Fowler. 1986. J. Cell. Biochem. 31:1-9; 1996. Curr. Opin. Cell Biol. 8:86-96). No clear function has yet been attributed to these complexes. Using a mathematical model for the structure of the red blood cell spectrin skeleton (M. J. Saxton. 1992. J. Theor. Biol. 155:517-536), we have explored a possible role for myosin II bipolar minifilaments in the restoration of the membrane skeleton, which may be locally damaged by major mechanical or chemical stress. We propose that the establishment of stable links between distant antiparallel actin protofilaments after a local myosin II activation may initiate the repair of the disrupted area. We show that it is possible to define conditions in which the calculated number of myosin II minifilaments bound to actin protofilaments is consistent with the estimated number of myosin II minifilaments present in the red blood cells. A clear restoration effect can be observed when more than 50% of the spectrin polymers of a defined area are disrupted. It corresponds to a significant increase in the spectrin density in the protein free region of the membrane. This may be involved in a more complex repair process of the red blood cell membrane, which includes the vesiculation of the bilayer and the compaction of the disassembled spectrin network.  (+info)

The forward rate of binding of surface-tethered reactants: effect of relative motion between two surfaces. (8/9460)

The reaction of molecules confined to two dimensions is of interest in cell adhesion, specifically for the reaction between cell surface receptors and substrate-bound ligand. We have developed a model to describe the overall rate of reaction of species that are bound to surfaces under relative motion, such that the Peclet number is order one or greater. The encounter rate between reactive species is calculated from solution of the two-dimensional convection-diffusion equation. The probability that each encounter will lead to binding depends on the intrinsic rate of reaction and the encounter duration. The encounter duration is obtained from the theory of first passage times. We find that the binding rate increases with relative velocity between the two surfaces, then reaches a plateau. This plateau indicates that the increase in the encounter rate is counterbalanced by the decrease in the encounter duration as the relative velocity increases. The binding rate is fully described by two dimensionless parameters, the Peclet number and the Damkohler number. We use this model to explain data from the cell adhesion literature by incorporating these rate laws into "adhesive dynamics" simulations to model the binding of a cell to a surface under flow. Leukocytes are known to display a "shear threshold effect" when binding selectin-coated surfaces under shear flow, defined as an increase in bind rate with shear; this effect, as calculated here, is due to an increase in collisions between receptor and ligand with increasing shear. The model can be used to explain other published data on the effect of wall shear rate on the binding of cells to surfaces, specifically the mild decrease in binding within a fixed area with increasing shear rate.  (+info)

Hyperalgesia is a medical term that describes an increased sensitivity to pain. It occurs when the nervous system, specifically the nociceptors (pain receptors), become excessively sensitive to stimuli. This means that a person experiences pain from a stimulus that normally wouldn't cause pain or experiences pain that is more intense than usual. Hyperalgesia can be a result of various conditions such as nerve damage, inflammation, or certain medications. It's an important symptom to monitor in patients with chronic pain conditions, as it may indicate the development of tolerance or addiction to pain medication.

Mechanical stress, in the context of physiology and medicine, refers to any type of force that is applied to body tissues or organs, which can cause deformation or displacement of those structures. Mechanical stress can be either external, such as forces exerted on the body during physical activity or trauma, or internal, such as the pressure changes that occur within blood vessels or other hollow organs.

Mechanical stress can have a variety of effects on the body, depending on the type, duration, and magnitude of the force applied. For example, prolonged exposure to mechanical stress can lead to tissue damage, inflammation, and chronic pain. Additionally, abnormal or excessive mechanical stress can contribute to the development of various musculoskeletal disorders, such as tendinitis, osteoarthritis, and herniated discs.

In order to mitigate the negative effects of mechanical stress, the body has a number of adaptive responses that help to distribute forces more evenly across tissues and maintain structural integrity. These responses include changes in muscle tone, joint positioning, and connective tissue stiffness, as well as the remodeling of bone and other tissues over time. However, when these adaptive mechanisms are overwhelmed or impaired, mechanical stress can become a significant factor in the development of various pathological conditions.

I'm sorry for any confusion, but "mechanical processes" is not a specific medical term. However, in a broader scientific context, mechanical processes refer to actions or events that involve forces and the movement or conversion of energy. This could include physical movements or manipulations of the body or bodily systems, such as surgical procedures, or the functioning of mechanical medical devices like pacemakers. If you have a more specific context in mind, I'd be happy to help further!

Biomechanics is the application of mechanical laws to living structures and systems, particularly in the field of medicine and healthcare. A biomechanical phenomenon refers to a observable event or occurrence that involves the interaction of biological tissues or systems with mechanical forces. These phenomena can be studied at various levels, from the molecular and cellular level to the tissue, organ, and whole-body level.

Examples of biomechanical phenomena include:

1. The way that bones and muscles work together to produce movement (known as joint kinematics).
2. The mechanical behavior of biological tissues such as bone, cartilage, tendons, and ligaments under various loads and stresses.
3. The response of cells and tissues to mechanical stimuli, such as the way that bone tissue adapts to changes in loading conditions (known as Wolff's law).
4. The biomechanics of injury and disease processes, such as the mechanisms of joint injury or the development of osteoarthritis.
5. The use of mechanical devices and interventions to treat medical conditions, such as orthopedic implants or assistive devices for mobility impairments.

Understanding biomechanical phenomena is essential for developing effective treatments and prevention strategies for a wide range of medical conditions, from musculoskeletal injuries to neurological disorders.

I'm sorry for any confusion, but "mechanical phenomena" is not a standard medical term. The term "mechanical phenomenon" is more commonly used in the fields of physics and engineering to refer to events or processes that involve physical forces and movements, such as the movement of a lever or the flow of a fluid due to pressure differences.

If you have any questions about a specific medical concept or condition, I would be happy to try to help you with that instead!

Artificial respiration is an emergency procedure that can be used to provide oxygen to a person who is not breathing or is breathing inadequately. It involves manually forcing air into the lungs, either by compressing the chest or using a device to deliver breaths. The goal of artificial respiration is to maintain adequate oxygenation of the body's tissues and organs until the person can breathe on their own or until advanced medical care arrives. Artificial respiration may be used in conjunction with cardiopulmonary resuscitation (CPR) in cases of cardiac arrest.

Cellular mechanotransduction is the process by which cells convert mechanical stimuli into biochemical signals, resulting in changes in cell behavior and function. This complex process involves various molecular components, including transmembrane receptors, ion channels, cytoskeletal proteins, and signaling molecules. Mechanical forces such as tension, compression, or fluid flow can activate these components, leading to alterations in gene expression, protein synthesis, and cell shape or movement. Cellular mechanotransduction plays a crucial role in various physiological processes, including tissue development, homeostasis, and repair, as well as in pathological conditions such as fibrosis and cancer progression.

In medicine, elasticity refers to the ability of a tissue or organ to return to its original shape after being stretched or deformed. This property is due to the presence of elastic fibers in the extracellular matrix of the tissue, which can stretch and recoil like rubber bands.

Elasticity is an important characteristic of many tissues, particularly those that are subjected to repeated stretching or compression, such as blood vessels, lungs, and skin. For example, the elasticity of the lungs allows them to expand and contract during breathing, while the elasticity of blood vessels helps maintain normal blood pressure by allowing them to expand and constrict in response to changes in blood flow.

In addition to its role in normal physiology, elasticity is also an important factor in the diagnosis and treatment of various medical conditions. For example, decreased elasticity in the lungs can be a sign of lung disease, while increased elasticity in the skin can be a sign of aging or certain genetic disorders. Medical professionals may use techniques such as pulmonary function tests or skin biopsies to assess elasticity and help diagnose these conditions.

Physical stimulation, in a medical context, refers to the application of external forces or agents to the body or its tissues to elicit a response. This can include various forms of touch, pressure, temperature, vibration, or electrical currents. The purpose of physical stimulation may be therapeutic, as in the case of massage or physical therapy, or diagnostic, as in the use of reflex tests. It is also used in research settings to study physiological responses and mechanisms.

In a broader sense, physical stimulation can also refer to the body's exposure to physical activity or exercise, which can have numerous health benefits, including improving cardiovascular function, increasing muscle strength and flexibility, and reducing the risk of chronic diseases.

Tensile strength is a material property that measures the maximum amount of tensile (pulling) stress that a material can withstand before failure, such as breaking or fracturing. It is usually measured in units of force per unit area, such as pounds per square inch (psi) or pascals (Pa). In the context of medical devices or biomaterials, tensile strength may be used to describe the mechanical properties of materials used in implants, surgical tools, or other medical equipment. High tensile strength is often desirable in these applications to ensure that the material can withstand the stresses and forces it will encounter during use.

The Elastic Modulus, also known as Young's modulus, is a measure of the stiffness of a material. It is defined as the ratio of stress (force per unit area) to strain (partial deformation or change in length per unit length) in the elastic range of deformation of a material. In other words, it measures how much a material will deform (change in length or size) when subjected to a given amount of force. A higher elastic modulus indicates that a material is stiffer and less likely to deform, while a lower elastic modulus indicates that a material is more flexible and will deform more easily. The elastic modulus is typically expressed in units of Pascals (Pa) or Gigapascals (GPa).

Mechanical Ventilators are medical devices that assist with breathing by providing mechanical ventilation to patients who are unable to breathe sufficiently on their own. These machines deliver breaths to the patient through an endotracheal tube or a tracheostomy tube, which is placed in the windpipe (trachea). Mechanical Ventilators can be set to deliver breaths at specific rates and volumes, and they can also be adjusted to provide varying levels of positive end-expiratory pressure (PEEP) to help keep the alveoli open and improve oxygenation.

Mechanical ventilation is typically used in critical care settings such as intensive care units (ICUs), and it may be employed for a variety of reasons, including respiratory failure, sedation, neuromuscular disorders, or surgery. Prolonged use of mechanical ventilation can lead to complications such as ventilator-associated pneumonia, muscle weakness, and decreased cardiac function, so the goal is usually to wean patients off the ventilator as soon as possible.

Elastic and viscous stresses are usually combined under the name mechanical stress. Significant stress may exist even when ... Often, mechanical bodies experience more than one type of stress at the same time; this is called combined stress. In normal ... Because mechanical stresses easily exceed a million Pascals, MPa, which stands for megapascal, is a common unit of stress. ... energy tensor Stress-strain curve Stress concentration Transient friction loading Tensile strength Thermal stress Virial stress ...
Mechanical Engineers., 209, 51-58 (1995) [6] S. Shakar, Vibratory Stress Relief of Mild Steel Weldments, PhD Dissertation, ... This stress is called residual stress, because it remains in a solid material after the original cause of the stress has been ... Vibratory Stress Relief, often abbreviated VSR, is a non-thermal stress relief method used by the metal working industry to ... "ASM Handbook of Residual Stress and Deformation in Steel", 2001 p.54-67 [4] R. Dawson and D.G. Moffat, Vibratory Stress Relief ...
"Flexure of Beams" (PDF). Mechanical Engineering Lectures. McMaster University.[permanent dead link] Day, Michael A. (2004), " ... The shear stress is imparted onto the boundary as a result of this loss of velocity. For a Newtonian fluid, the shear stress at ... Shear stress (often denoted by τ (Greek: tau)) is the component of stress coplanar with a material cross section. It arises ... microS Shear Stress Sensor, MSE} Große, S.; Schröder, W. (2009), "Two-Dimensional Visualization of Turbulent Wall Shear Stress ...
1999) Mechanical Behaviors of Materials. Prentice Hall, Inc. Page 301. H., Courtney, Thomas (2013). Mechanical Behavior of ... Resolved shear stress (RSS) is the shear component of an applied tensile or compressive stress resolved along a slip plane that ... In materials science, critical resolved shear stress (CRSS) is the component of shear stress, resolved in the direction of slip ... To understand the relationship between stress and temperature observed, we first divide the critical resolved shear stress into ...
"Mechanical Properties of Materials". (Articles with short description, Short description is different from Wikidata, Elasticity ... The true stress and strain can be expressed by engineering stress and strain. For true stress, σ t = F A = F A 0 A 0 A = F A 0 ... The stress-strain curve for this material is plotted by elongating the sample and recording the stress variation with strain ... In engineering and materials science, a stress-strain curve for a material gives the relationship between stress and strain. It ...
American Society of Mechanical Engineers. Liu, M.; et al. (2015). "An improved semi-analytical solution for stress at round-tip ... In fracture mechanics, the stress intensity factor (K) is used to predict the stress state ("stress intensity") near the tip of ... for plane stress. The critical stress intensity factor for plane stress is often written as K c {\displaystyle K_{\rm {c}}} . ... In 1957, G. Irwin found that the stresses around a crack could be expressed in terms of a scaling factor called the stress ...
Soboyejo, Winston (2003). "3.6 Hydrostatic and Deviatoric Stress". Mechanical properties of engineered materials. Marcel Dekker ... also known as volumetric stress, is a component of stress which contains uniaxial stresses, but not shear stresses. A ... Hydrostatic stress is equivalent to the average of the uniaxial stresses along three orthogonal axes and can be calculated from ... Because the hydrostatic stress is isotropic, it acts equally in all directions. In tensor form, the hydrostatic stress is equal ...
Shigley, Joseph Edward (1977). Mechanical Engineering Design (Third ed.). McGraw-Hill. stress at round-tip notches an improved ... In solid mechanics, a stress concentration (also called a stress raiser or a stress riser or notch sensitivity) is a location ... Instead, the stress intensity factor which defines the scaling of the stress field around a crack tip, is used. There are ... The stress concentration factor, K t {\displaystyle K_{t}} , is the ratio of the highest stress σ max {\displaystyle \sigma _{\ ...
doi:10.1016/0022-5096(76)90024-7. Soboyejo, W. O. (2003). "12.4.2 Cleavage Fracture". Mechanical properties of engineered ... In continuum mechanics, stress triaxiality is the relative degree of hydrostatic stress in a given stress state. It is often ... A higher stress triaxiality corresponds to a stress state which is primarily hydrostatic rather than deviatoric. High stress ... defined as the ratio of Cauchy stress first principal invariant divided by effective stress η D C ≡ 3 σ m / σ e f = I 1 / 3 J 2 ...
Soboyejo, W. O. (2003). Mechanical properties of engineered materials. Marcel Dekker. pp. 222-228. ISBN 9780824789008. OCLC ... On a stress-strain curve, the flow stress can be found anywhere within the plastic regime; more explicitly, a flow stress can ... although the flow stress could decrease due to any recovery process. In continuum mechanics, the flow stress for a given ... The flow stress is an important parameter in the fatigue failure of ductile materials. Fatigue failure is caused by crack ...
Soboyejo, Wole O. (2003). "6.4 Movement of Dislocations". Mechanical properties of engineered materials. Marcel Dekker. ISBN 0- ... Peierls stress depends on the size and width of a dislocation and the distance between planes. Because of this, Peierls stress ... Peierls stress (also known as the lattice friction stress) is the force (first described by Rudolf Peierls and modified by ... As temperature increases, the vibration of atoms increases, and thus both peierls stress and yield strength decrease as a ...
"Mechanical Stress/Strength Interference Theory" (PDF). Retrieved 26 February 2013. http://reliawiki.org/index.php/Stress- ... Stress-strength analysis is the analysis of the strength of the materials and the interference of the stresses placed on the ... Stress-Strength Analysis is a tool used in reliability engineering. Environmental stresses have a distribution with a mean ( μ ... This overlap is also referred to stress-strength interference. If the distributions for both the stress and the strength both ...
Lalanne, Christian (5 January 2010). Mechanical Vibration and Shock, Fatigue Damage. John Wiley & Sons, 2010. p. 6. ISBN ... However, cyclic axial stresses and cyclic torsional stresses also exist. An example of cyclic axial stress would be a bungee ... Mean stress is the time average of the principal stress. The definition of alternating stress varies between different sources ... Cyclic stress is the distribution of forces (aka stresses) that change over time in a repetitive fashion. As an example, ...
"Mechanical Properties of Ceramics" by John B. Wachtman, W. Roger Cannon, and M. John Matthewson. Chapter 8. (Webarchive ... The stresses can be the result of the crevice loads due to stress concentration, or can be caused by the type of assembly or ... Stress corrosion cracking mainly affects metals and metallic alloys. A comparable effect also known as environmental stress ... "Irradiation-Assisted Stress-Corrosion Cracking", Stress-Corrosion Cracking, ASM International, pp. 191-220, 2017-01-01, doi: ...
Of decisive importance for the piezoelectric effect is the change of polarization P when applying a mechanical stress. This ... Drawing on this knowledge, both René Just Haüy and Antoine César Becquerel posited a relationship between mechanical stress and ... But conventionally, because strain and stress are all symmetric tensors, the subscript of strain and stress can be relabeled in ... the applied mechanical stress. The change in P appears as a variation of surface charge density upon the crystal faces, i.e. as ...
For some women this may reduce stress leakage, however it is not clear how well these mechanical devices help women with stress ... Stress incontinence, also known as stress urinary incontinence (SUI) or effort incontinence is a form of urinary incontinence. ... Medications are not recommended for those with stress incontinence. Some behavioral changes can improve stress incontinence. It ... Stress incontinence can worsen during the week before the menstrual period. At that time, lowered estrogen levels may lead to ...
"Residual Stresses." In Mechanical Behavior of Materials, 308-321. Cambridge University Press. ISBN 978-0-521-84670-7 Cary, ... When parts are heated for stress relief, the process may also be known as stress relief bake. Cooling parts for stress relief ... residual stresses are stresses that remain in a solid material after the original cause of the stresses has been removed. ... Mechanical methods to relieve undesirable surface tensile stresses and replace them with beneficial compressive residual ...
Griffin, Michael G.; Resick, Patricia A.; Waldrop, Angela E.; Mechanic, Mindy B. (2003). "Participation in trauma research: Is ... Journal of Traumatic Stress. 16 (6): 567-571. doi:10.1023/B:JOTS.0000004080.50361.f3. ISSN 1573-6598. PMID 14690354. S2CID ... Journal of Traumatic Stress. 13 (3): 413-426. doi:10.1023/A:1007777006605. ISSN 1573-6598. PMID 10948482. S2CID 46039077. ... Stress (biological and psychological), Abuse, Harassment and bullying, Clinical psychology, Counseling, Anxiety disorders, ...
These included strength against; chemicals, thermal shift, and mechanical stress. "Volumetric Pipette". Chemistry Glossary. " ...
This feature cuts down on mechanical stress. An additional feature of the Linerlock is the addition of a ball detent. This ...
"Stress Analysis of Cracks Handbook, Third Edition". American Society of Mechanical Engineers. Archived from the original on ... Hiroshi Tada was a mechanical engineer with highly notable works in the field of fracture mechanics. He was also well known as ... Louis and co-author of Stress Analysis of Cracks Handbook. "Far East Meets Midwest: The Performers". Circus Day Foundation. ... Tada was an affiliate professor of mechanical engineering at the McKelvey School of Engineering at Washington University in St ...
The stress history in Figure 2 is reduced to tensile peaks in Figure 3 and compressive valleys in Figure 4. From the tensile ... Mechanical Behavior of Materials. 1: 371-380. Sunder, R.; Seetharam, S. A.; Bhaskaran, T. A. (1984). "Cycle counting for ... At the end of the smaller cycle, the material resumes the stress-strain path of the original cycle, as if the interruption had ... Assign a magnitude to each half-cycle equal to the stress difference between its start and termination. Pair up half-cycles of ...
Temperature changes create thermally induced mechanical stress. This stress can create low level acoustic emissions from ...
Nonnenmacher, T. F., & Glöckle, W. G. (1991). A fractional model for mechanical stress relaxation. Philosophical magazine ... into the time-dependent relaxation behavior of viscoelastic materials are characterized by a very fast decrease of the stress ...
Shoghi, K.; Rao, H. V.; Barrans, Simon (2004). "Stress in V-section band clamps. Proceedings of the Institute of Mechanical ... Marman clamps are used extensively in spaceflight systems and are common mechanical load-transfer and clamping mechanisms for ... Engineering Part C" (PDF). Journal of Mechanical Engineering Science. 3. 218: 251-261. doi:10.1243/095440604322900381. ...
Articles with short description, Short description matches Wikidata, Mechanical tests). ... Non-intrusive stress measurement (system), or NSMS, is a method for determining dynamic blade stresses in rotating ... "Non-Intrusive Stress Measurement System" (PDF). Agilis. Retrieved 4 January 2013. "Non-Intrusive Stress Measurement System ( ... This information, in conjunction with a finite element model (FEM), can then be used to determine the dynamic stresses in a ...
... is used to describe any phenomena where the environment compromises a stressed material's mechanical performance ... which becomes a barrier for dislocation motion and builds up stress near the atoms. When the metal is stressed, the stress is ... It relies on both a corrosive environment and the presence of tensile (not compressive) stress. Sulfide stress cracking is the ... This ultimately leads to fracture at stresses less than the material's typical ultimate tensile stress. Polymers come in a wide ...
The Ramberg-Osgood equation was created to describe the non linear relationship between stress and strain-that is, the stress- ... 1] "Mechanical Properties of Materials , MechaniCalc". mechanicalc.com. Retrieved 2020-05-27. Hollomon, J. R. (1945). "Tensile ... Johnson-Cook flow stress model Ramberg, W., & Osgood, W. R. (1943). Description of stress-strain curves by three parameters. ... The equation is essentially assuming the elastic strain portion of the stress-strain curve, ε e {\displaystyle \varepsilon _{e ...
DBTT is a very important consideration in selecting materials that are subjected to mechanical stresses. A similar phenomenon, ... Choung, J (2008). "Study on True Stress Correction from Tensile Tests". Journal of Mechanical Science and Technology. 22 (6): ... Also, the true stress at the point of fracture is usually higher than the apparent value according to the plot. The load often ... Ductility is a mechanical property commonly described as a material's amenability to drawing (e.g. into wire). In materials ...
Differential stresses that develop as a result of non-uniform drying shrinkage are directly related to the rate at which the ... The inclusion of nanoparticles in a solid or liquid medium can substantially change its mechanical properties, such as ... Such stresses have been associated with a plastic-to-brittle transition in consolidated bodies, and can yield to crack ... Differential stresses arising from inhomogeneous densification have also been shown to result in the propagation of internal ...
... subjects products to vibration, shock, free fall, tumble or impact to determine potential ... What kind of mechanical stress testing does Nemko perform? With mechanical stress testing, the effects of vibration over a wide ... Mechanical stress testing Mechanical stress testing helps determine whether a device can remain functional when subjected to ... Mechanical stress either causes instant damage to the product or causes potential damage that may only be visible in long term ...
Vår pris 1519,-(portofritt). Kategorier: Byggeteknikk, landmåling og bygging, Materialvitenskap, Maskinteknikk, Dynamikk og statikk.
EFFECT OF OXIDATION STRESS ON THE MECHANICAL PROPERTY OF HUMAN HAIR Yoko Akiyama, Yusuke Doi, Yukako Matsue, Fumihito Mishima, ...
One of the characteristic bacteria phenotypes of antibiotic resistance (and more generally of a stress response) is ... How mechanical and electrical stimuli affect bacteria filamentation, a major cell stress response. ... In this context, we hypothesize that the interplay between mechanical cues (e.g. filament bending) and changes in the bacteria ... One of the characteristic bacteria phenotypes of antibiotic resistance (and more generally of a stress response) is ...
In summary, these results suggested that mechanical stress promotes LFCs to produce IGF-1, which facilitates col-I and col-III ... First, LFCs were isolated from 9 patients and cultured with or without mechanical stress exposure for different times. IGF-1, ... Therefore, we investigated the relationship between mechanical stress and collagen synthesis in the present study. ... the mechanism of mechanical stress in the formation of collagen remains unclear. ...
Keyboard Fidget Toy Mechanical Switch Keyboard Fingertip Fidget Button Stress Relief Sensory Toys Pocket Keyboard Toys - Buy ... Pocket Keyboard Toys,Keyboard Fidget Toy,Mechanical Pocket Keyboard Product on Alibaba.com ... Keyboard Fidget Toy Mechanical Switch Keyboard Fingertip Fidget Button Stress Relief Sensory Toys Pocket Keyboard Toys. ...
Gas-liquid flows in annulus are analyzed for fluids in large range of viscosity ratios. The geometry corresponds to a liquid bridge co-axially placed into an outer cylinder with solid walls. The internal core consists of soli... | Find, read and cite all the research you need on Tech Science Press
Department of Mechanical Engineering. Indian Institute of Technology Guwahati North Guwahati, Guwahati, Assam 781039 mechoff@ ... Evaluation of notch stress intensities at sharp V-notches using a point substitution method. [Conference Publication]. ...
Proliferation of Atomic Shuffling through Mechanical Stress on Cationic Disorder Li4FeMoO6 as a Cathode Material for a Lithium- ... A. K. Nanda Kumar, Arulraj, A., and Ramesha, K., "Proliferation of Atomic Shuffling through Mechanical Stress on Cationic ... HomePublicationsProliferation of Atomic Shuffling through Mechanical Stress on Cationic Disorder Li4FeMoO6 as a Cathode ... Herein, we report evidence of structural instabilities upon mechanical milling and electrochemical cycling of Li4FeMoO6. ...
A System for Calibration and Reliability Testing of MEMS Devices Under Mechanical Stress ... This paper reports on a setup and a method that enables the automated analysis of mechanical stress impact on MEMS devices. The ... A System for Calibration and Reliability Testing of MEMS Devices Under Mechanical Stress. Conference: MikroSystemTechnik - ...
Incorporating multi-material, thermos-mechanical, stress-related objectives or constraints is crucial for producing safe and ... This approach accommodates multi-material, thermo-mechanical, and stress-related objectives, or constraints, ensuring safe and ... Advances in Topology Optimization: Neural Network Approaches for Multi-Matieral, Thermo-Mechanical, and Stress-Constrained ... Advances in Topology Optimization: Neural Network Approaches for Multi-Matieral, Thermo-Mechanical, and Stress-Constrained ...
In-vivo imaging of root growth in response to localized mechanical stress. Second cycle, A2E. Uppsala: SLU, Dept. of Soil and ... stress in the same way as the impeded roots, even if the stress did not occur in their. environment. In the case, where the ... the responses of unimpeded roots to local mechanical stress of their neighbouring. roots. To do so, the primary or seminal ... kinematics analysis, time-lapse imaging, root growth rate, root curvature, soil heterogenety, local mechanical stress. ...
Modeling of Mechanical Stress Exerted by Cholesterol Crystallization on Atherosclerotic Plaques. Authors: Luo, Yuemei. Cui, ... 2016). Modeling of Mechanical Stress Exerted by Cholesterol Crystallization on Atherosclerotic Plaques. PLOS ONE, 11(5), ... The results demonstrate that (1) the peak circumference stress is proportionally dependent on the cholesterol crystal growth; ( ... 2) cholesterol crystals at the cap shoulder impose the highest peak circumference stress; and (3) spatial distributions of ...
... the details of the bending equipment solution and the calibration required for characterization of external mechanical stress ... is suited for use in probe station for electrical characterization of devices under controlled external mechanical stress. ... BÜHLER, R. T.; GIACOMINI, R. Open model for external mechanical stress of semiconductors and MEMS.IEEE International Conference ... is suited for use in probe station for electrical characterization of devices under controlled external mechanical stress.. ...
It has been shown that all stress and strain tensor components in the vicinity of inclusions take on non-zero values, including ... It has been shown that all stress and strain tensor components in the vicinity of inclusions take on nonzero values, including ... Thus, the free surface becomes rough under the action of internal forces originated from the inhomogeneous stress-strain fields ... Thus, the free surface becomes rough under the action of internal forces originated from the inhomogeneous stress-strain fields ...
... clearly shows that mechanical stress signals and immune responses play important roles in determining the wound healing mode. ... through mechanical stress signals.. 3. Interaction between Immune Response and Mechanical Stress in Wound Healing. 3.1. Immune ... 2. Mechanical Regulation in Wound Healing. 2.1. Mechanical Stress Is Involved in the Moderation of Wound Healing through the ... and mechanical stress [1]. These external stresses cause not only microscale damage, such as protein denaturation and ...
As a Mechanical Engineer you will be responsible for stress, vibration, and heat transfer analyses. Mechanical Engineer ... Key Responsibilities as Mechanical Engineer:. Perform stress analysis using complex finite element & classical book calculation ... Key attributes as Mechanical Engineer:. Bachelors Degree in Mechanical or Aerospace Engineering or closely related field with ... This is a full time position for the successful Mechanical Engineer. If you are interested in the role or want to find out more ...
... as mechanical stress reduces plant yield while it increases the propagation. ... Mechanical stress reduces plant yield and increases deseases. Mechanical stress reduces plant yield. Mechanical stress reduces ... Mechanical stress reduces plant yield. Mechanical stress reduces plant yield, physical disturbance of plants or plant parts. ... Ethylene has been implicate in many mechanical stress responses. (Biddington, 1986). Responses to mechanical stress may involve ...
... cells are permanently exposed to stress resulting from mechanical forces and their homeostasis relies on dedicated stress ... State-of-the-art technology will be used to apply mechanical stress in a highly defined manner to isolated cells and tissues, ... Mechanical stress protection operates during cell differentiation, adhesion and migration, and is of particular importance for ... The research unit will establish fundamental principles of mechanical stress protection in multicellular organisms and will ...
The effect of mechanical stresses generated by an extreme agitation intensity or a high aeration rate on growth parameters and ... N2 - The effect of mechanical stresses generated by an extreme agitation intensity or a high aeration rate on growth parameters ... AB - The effect of mechanical stresses generated by an extreme agitation intensity or a high aeration rate on growth parameters ... abstract = "The effect of mechanical stresses generated by an extreme agitation intensity or a high aeration rate on growth ...
Bio mechanical methods are frequently utilised together with additional therapeutic massage practices. Bio-Mechanical Treatment ... can be a form of massage that employs mechanical tactics to assist the body cure. ... Bio-Mechanical Stimulation, or BMS, can be a form of massage that employs mechanical tactics to assist the body cure. Bio ... Bio-Mechanical Stimulation - A Outstanding Way to Minimize Stress mineclef13 758 days ago News https://diigo.com Discuss ...
Review of mechanical testing, 3-D stress-strain relationship, complex and principal states of stress, yielding and fracture ... Mechanical failure caused by stresses, strains, and energy transfers in mechanical parts: conventional design concepts and ... M E 544 - Mechanical Systems Analysis (3 hours) Mathematical modeling of mechanical, electrical, pneumatic, hydraulic, and ... Mechanical Engineering Courses. M E 501 - Advanced Thermodynamics (3 hours) Laws and concepts of classical thermodynamics: real ...
Stress Analysis Engineer. *Thermo-fluid Engineer. *Systems Engineer. *Mechanical R&D Engineer ... Analyze machine elements and mechanical mechanisms with application to mechanical system design, development, and service; ... Explore other Mechanical Engineering Technology-related topics such as thermodynamics, fluid power, heat transfer, and their ... Click here to see the plan of study flow chart for the Mechanical Engineering Technology program. ...
This range allows for mechanical tension and metabolic stress to balance out while allowing for high volumes of training, thus ... Mechanical tension. This is based on the load lifted. Training heavy elicits the most mechanical tension. ... Mechanical tension. This is based on the load lifted. Training heavy elicits the most mechanical tension. ... better capacity for mechanical tension) and muscle endurance (better capacity for metabolic stress). Varying the repetition ...
Mechanical Behaviour Questions and Answers - True Stress Strain Curve *Mechanical Metallurgy Questions and Answers - Tension ... Class 11 Physics MCQ - Solids Mechanical Properties - Stress-Strain Curve *Strength of Materials Questions and Answers - Stress ... Mechanical Behaviour Questions and Answers - Tension Test and Stress Strain Curve *Materials Science Questions and Answers - ... Mechanical Metallurgy Questions and Answers - Tension Test - True-Stress-True Strain Curve - 1 ...
"Stresses in Hollow Rotating Cylinder with Longitudinal Split" Strojniški vestnik - Journal of Mechanical Engineering [Online], ... "Stresses in Hollow Rotating Cylinder with Longitudinal Split." Strojniški vestnik - Journal of Mechanical Engineering [Online ... Stresses in Hollow Rotating Cylinder with Longitudinal Split. Strojniški vestnik - Journal of Mechanical Engineering. [Online] ... Journal of Mechanical Engineering DO - KW - hollow rotating cylinder; longitudinal split; N2 - Investigation of the stress ...
Hertz Stress Whitepaper Select. English Product Specification. Mechanical. Shell Style. Panel, PCB or cable mounted. ...
Biaxial stresses, torsion, unsymmetrical bending of beams, shear centers, contact stresses, failure theory, and other selected ... Mechanical Engineering ME Program Graduate Catalog Mechanical Engineering. Graduate Catalog Mechanical Engineering. Ali Fatemi ... MECH 6346 - Adv Mechanical Controls (3). Advanced modeling of mechanical control systems; review of digital and optimal control ... MECH 6344 - Mechanical Controls (3). Fundamental classical control concepts; modeling of linear mechanical control systems; ...
Formula Student is run by the Institute for Mechanical Engineers, and is an annual student engineering competition held in the ... Our motorsport, automotive and mechanical engineering courses are fully accredited by the Institution of Engineering and ... Technology (IET) and the Institution of Mechanical Engineers (IMechE) on behalf of the Engineering Council. This includes an ...
  • Sustained internal tissue loads (deformations, mechanical strains and stresses) which develop during immobile weight-bearing postures such as while in bed or in a chair were identified as a fundamental cause for the onset and progression of pressure ulcers (PUs), particularly of the deep tissue injury (DTI) type. (iucc.ac.il)
  • Due to the nature of welding process involving localized heat generation from moving heat source (s), rapid heating in the welded structures, and subsequent rapid cooling, problems such as residual stresses and distortions of welded structures remain great challenges to welding practitioners, designers and modeler. (intechopen.com)
  • In recent years, various aspects and interests in the numerical modeling of welding residual stresses and distortions, mostly using finite element method, have been elaborated by researchers. (intechopen.com)
  • Teng & Lin (1998 ) predicted the residual stresses during one-pass arc welding in steel plate using ANSYS software and discussed the effects of travel speed, specimen size, external mechanical constraints and preheating on the residual stresses. (intechopen.com)
  • This approach accommodates multi-material, thermo-mechanical, and stress-related objectives, or constraints, ensuring safe and efficient designs. (anl.gov)
  • High density 3D-LSI with W-TSV for signal line and Cu-TSV for power/GND line, and Cu-TSV containing W stress absorbing layers were investigated for the induced thermo-mechanical stress in 3D-LSI Si die/wafer after wafer thinning and bonding using micro-Raman spectroscopic technique. (elsevierpure.com)
  • Stress mapping analysis revealed that W-TSV has induced less thermo-mechanical stress in LSI Si, whereas the Cu-TSV has induced large amount of stress. (elsevierpure.com)
  • 300 MPa of compressive stress after heating at 400 °C. This property can be readily employed to minimize the residual thermo-mechanical stress in the bonded high density 3D-LSI. (elsevierpure.com)
  • abstract = {Investigation of the stress state in a rotating ring Is one of the basic steps In studying the bursting mechanism In different rotating machine components and tolls, for example a grinding wheel. (sv-jme.eu)
  • For example, an object being pulled apart, such as a stretched elastic band, is subject to tensile stress and may undergo elongation. (wikipedia.org)
  • According to previous clinical and in vitro studies, the accumulation of tensile stress to these ligaments may be responsible for ligament ossification. (elsevierpure.com)
  • The findings obtained in the present study strongly suggest that repetitive tensile stress to the spinal ligaments is one of the important causes of ligament ossification in the spine. (elsevierpure.com)
  • We developed a two-dimensional finite element method model of atherosclerotic plaques containing expanding cholesterol crystals and investigated the effect of the magnitude and distribution of crystallization on the peak circumferential stress born by the cap. (ntu.edu.sg)
  • and (3) spatial distributions of cholesterol crystals have a significant impact on the peak circumference stress: evenly distributed cholesterol crystals exert less peak circumferential stress on the cap than concentrated crystals. (ntu.edu.sg)
  • In their paper, they compare the maximum circumferential stress which appears on the Inner side of the longitudinal cross section planes of the hollow cylinder, the stresses being determined using several different methods: curved beam theory, straight beam theory and finite element method (FEM). (sv-jme.eu)
  • They found that the maximum circumferential stresses determined by the straight beam theory and FEM are almost the same, whereas the other methods give lower values of maximum circumferential stresses. (sv-jme.eu)
  • Large differences among the maximum circumferential stresses occur near the inner radii. (sv-jme.eu)
  • By the curved beam theory and FEM, the maximum circumferential stresses Increase for radii ration from 0.15 downwards but, using the other two methods the same stresses decrease at these radii ratia. (sv-jme.eu)
  • With rise of temperature, molecular bonds weakens and fracture occurs at a lesser load, hence area under stress strain curve decreases. (sanfoundry.com)
  • Karjalainen-Roikonen, P & Wallin, K 1992, Analysis of fracture mechanical tests for stress corrosion cracking . (vtt.fi)
  • Stress that exceeds certain strength limits of the material will result in permanent deformation (such as plastic flow, fracture, cavitation) or even change its crystal structure and chemical composition. (wikipedia.org)
  • In liquids and gases, only deformations that change the volume generate persistent elastic stress. (wikipedia.org)
  • With mechanical stress testing, the effects of vibration over a wide range of frequency and acceleration levels can be simulated as well as shock, free fall, drop, tumble and impact according to IEC 60068-series. (nemko.com)
  • Mechanical stress "thigmomorphogenesis," whereas plant response to a nontactile (shaking, vibration, wind) treatment was termed "seismomorphogenesis" by Mitchell et al. (hortomallas.com)
  • After adjustment for age, race, and known cardiac risk factors, there was no significant association between marijuana use beforehand and the composite outcome, which included death, cardiac arrest, shock, mechanical ventilation , or intra-aortic balloon pump (IABP) placement, after patients experienced an MI. (medscape.com)
  • Communication Difficulties and Psychological Stress in Patients Receiving Mechanical Ventilation. (bvsalud.org)
  • The Drinker and Shaw tank-type ventilator of 1929 was one of the first negative-pressure machines widely used for mechanical ventilation. (medscape.com)
  • Intensive use of positive-pressure mechanical ventilation gained momentum during the polio epidemic in Scandinavia and the United States in the early 1950s. (medscape.com)
  • Many factors affect the decision to begin mechanical ventilation. (medscape.com)
  • Because no mode of mechanical ventilation can cure a disease process, the patient should have a correctable underlying problem that can be resolved with the support of mechanical ventilation. (medscape.com)
  • Conclusion PGE2 secretion in human skin keratinocytes may increase after mechanical damage, which may be associated with oxidative stress mediated by increased intracellular ROS generation and NOX activity. (shsmu.edu.cn)
  • Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of Duchenne muscular dystrophy: a comparison with the gold standard, α-methyl prednisolone. (uniba.it)
  • Resveratrol (100mg/kg i.p. 5days/week), apocynin (38mg/kg/day per os), taurine (1g/kg/day per os), and PDN (1mg/kg i.p., 5days/week) were administered for 4-5 weeks to mdx mice in parallel with a standard protocol of treadmill exercise and the outcome was evaluated with a multidisciplinary approach in vivo and ex vivo on pathology-related end-points and biomarkers of oxidative stress. (uniba.it)
  • All the compounds reduced the production of superoxide anion, assessed by dihydroethidium staining, with apocynin being as effective as PDN, and ameliorated electrophysiological biomarkers of oxidative stress. (uniba.it)
  • An object being pushed together, such as a crumpled sponge, is subject to compressive stress and may undergo shortening. (wikipedia.org)
  • Strain inside a material may arise by various mechanisms, such as stress as applied by external forces to the bulk material (like gravity) or to its surface (like contact forces, external pressure, or friction). (wikipedia.org)
  • The rationale was to target the overproduction of reactive oxygen species (ROS) via disease-related pathways that are worsened by mechanical-metabolic impairment such as inflammation and over-activity of NADPH oxidase (NOX) (taurine and apocynin, respectively) or the failing ROS detoxification mechanisms via sirtuin-1 (SIRT1)-peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) (resveratrol). (uniba.it)
  • In the present study, we completed some preliminary evaluations of the effects of adding suspension mechanisms to the mechanical arms on grinder vibrations in a simulated work task. (cdc.gov)
  • Our contribution presents a mathematical approach to determine the function of the stress state in the longitudinal section planes of the hollow cylinder, using the Airy function. (sv-jme.eu)
  • Mathematical modeling of mechanical, electrical, pneumatic, hydraulic, and hybrid physical systems emphasizing a unified approach such as the Bond graph technique. (bradley.edu)
  • With those tools, Augustin-Louis Cauchy was able to give the first rigorous and general mathematical model of a deformed elastic body by introducing the notions of stress and strain. (wikipedia.org)
  • This paper reports on a setup and a method that enables the automated analysis of mechanical stress impact on MEMS devices. (vde-verlag.de)
  • GIACOMINI, R. Open model for external mechanical stress of semiconductors and MEMS.IEEE International Conference on Microelectronic Test Structures, p. 189-193, March, 2018. (edu.br)
  • She also stressed to heart wire from Medscape that the investigators aren't advocating marijuana use. (medscape.com)
  • IGF-1, col-I, and col-III were significantly increased in stressed LFCs compared to nonstressed LFCs. (hindawi.com)
  • In this context, we hypothesize that the interplay between mechanical cues (e.g. filament bending) and changes in the bacteria membrane potential play a key role to regulate bacterial filamentation. (europa.eu)
  • Plants use such mechanical cues to detect e.g. herbivores, wind, neighbouring plants or to find supports to climb on. (lu.se)
  • It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. (nature.com)
  • Moreover, increased IGF-1 promotes hypertrophy of various tissues [ 14 - 17 ], and mechanical stress plays a vital role in IGF-1 formation [ 18 , 19 ]. (hindawi.com)
  • Few long-term effects are expect from mechanical conditioning of transplants sincere productive tissues generally are not treat. (hortomallas.com)
  • Here, we used computational modeling and engineered epithelial tissues of precise geometry to define the experimental parameters that are required to measure directly the mechanical stress profile of 3D tissues embedded within native type I collagen. (princeton.edu)
  • Spatially resolved mechanical maps can provide insight into the types and magnitudes of physical parameters that are sensed and interpreted by multicellular tissues during normal and pathological processes. (princeton.edu)
  • 1991). Both the physical and physiological long-term effects of mechanical conditioning must be more adequately define. (hortomallas.com)
  • Objective To investigate the effects of mechanical damage on prostaglandin E2 (PGE2) secretion in human skin keratinocytes, and explore its possible mechanism. (shsmu.edu.cn)
  • Working with the manager and other mechanics to diagnose and repair the mechanical and electrical components of vehicles. (simplyhired.com)
  • In continuum mechanics, stress is a physical quantity that describes forces present during deformation. (wikipedia.org)
  • Bio-Mechanical Stimulation, or BMS, can be a form of massage that employs mechanical tactics to assist the body cure. (techdirt.stream)
  • Mechanical stimulation was also combined with a Rho inhibitor to probe their coupled effects on FN. (nature.com)
  • Mechanical stimulation coupled with chemical stimulation also revealed an increase in FN fibrils around the cell periphery. (nature.com)
  • These results show that mechanical stimulation directly affected FN reorganization and recruitment, despite perturbation by chemical stimulation. (nature.com)
  • Though most of these studies have probed these questions through chemical stimulation, mechanical stimulation has been shown to be extremely important. (nature.com)
  • Thus a thorough understanding of both mechanical and chemical stimulation separately, as well as coupled together, is integral to gain insight into FN synthesis, function and the effects of various pathology-induced abnormalities that can perturb this multi-functional protein. (nature.com)
  • The mission of the Mechanical Engineering Technology (MET) program is to provide a world class engineering technology education that combines engineering physics and mathematics principles with materials science to design, analyze, manufacture, and maintain mechanical systems through hands on projects and active learning experiences. (shsu.edu)
  • Click here to see the plan of study flow chart for the Mechanical Engineering Technology program. (shsu.edu)
  • Explore other Mechanical Engineering Technology-related topics such as thermodynamics, fluid power, heat transfer, and their applications. (shsu.edu)
  • Strojniški vestnik - Journal of Mechanical Engineering, 41 (1-2), 19-28. (sv-jme.eu)
  • Our motorsport, automotive and mechanical engineering courses are fully accredited by the Institution of Engineering and Technology (IET) and the Institution of Mechanical Engineers (IMechE) on behalf of the Engineering Council. (brookes.ac.uk)
  • Formula Student is run by the Institute for Mechanical Engineers, and is an annual student engineering competition held in the UK. (brookes.ac.uk)
  • The "mechanical" in Mechanical Engineering refers to things that move. (purdue.edu)
  • I. The department of Mechanical Engineering offers a graduate program leading to the Master of Science degree with a major in Mechanical Engineering. (memphis.edu)
  • A more detailed description of the information listed below will be given by the Coordinator of Graduate Studies to students admitted into the Mechanical Engineering MS program. (memphis.edu)
  • Upon completion of the thesis, the student must successfully pass an oral examination to assess mastery of the thesis topic and to evaluate the student's knowledge in mechanical engineering. (memphis.edu)
  • Students selecting the non-thesis option must pass an oral comprehensive examination to demonstrate mastery of mechanical engineering topics commensurate with the degree to be awarded. (memphis.edu)
  • Students who wish to take mechanical engineering courses must receive approval to register after consultation with the departmental graduate coordinator or with the faculty advisory committee. (memphis.edu)
  • See the following link for information about the doctoral program in Mechanical Engineering. (memphis.edu)
  • DETAILS Educational Background - Degree in Mechanical Engineering ( BE / B Tech ) from reputed UniversityExperience - 2-10 yrs experience as Design Engineer in Consultancy / Des. (timesjobs.com)
  • DETAILS Educational Background - Degree in Mechanical Engineering ( BE / B Tech ) from reputed UniversityExperience - 15 to 20 yrs with at least 8 yrs working experience in Consul. (timesjobs.com)
  • These differences in yield response to mechanical stress again may be due to differences in cultivars or species. (hortomallas.com)
  • Purpose There are limited data on whether differences exist in left ventricular (LV) mechanical dyssynchrony indices derived from stress versus rest gated positron emission tomography (PET) in patients with normal myocardial perfusion imaging (MPI). (elsevierpure.com)
  • Incorporating multi-material, thermos-mechanical, stress-related objectives or constraints is crucial for producing safe and efficient designs. (anl.gov)
  • DETAILS Roles and ResponsibilitiesUrgent Requirement for Asst. Manager - Mechanical ( Power Plant ) Monitoring the proper operation & amp;maintenance of turbine & boiler auxiliari. (timesjobs.com)
  • If the deformation changes gradually with time, even in fluids there will usually be some viscous stress, opposing that change. (wikipedia.org)
  • Answer:a Explanation: Tension test determines the parameters related to stress strain curve and also reduction and elongation in area and length can be found respectively. (sanfoundry.com)
  • Training heavy elicits the most mechanical tension. (stack.com)
  • This range allows for mechanical tension and metabolic stress to balance out while allowing for high volumes of training, thus optimizing size gains. (stack.com)
  • Training in a variety of rep ranges may be superior for gains in muscle size and increasing strength (better capacity for mechanical tension) and muscle endurance (better capacity for metabolic stress). (stack.com)
  • The unique concept enables you to perform dynamic mechanical analysis in bending, tension, compression, and torsion, standard and highly sophisticated rheological measurements as well as thermomechanical analysis (TMA) with one instrument. (anton-paar.com)
  • Inspect vehicle engine and mechanical/electrical components to diagnose issues accurately. (simplyhired.com)
  • We found that to calculate the stresses accurately in these settings, we had to account for mechanical heterogeneities within the matrix, which we visualized and quantified using confocal reflectance and atomic force microscopy. (princeton.edu)
  • Mechanical stress reduces plant yield, physical disturbance of plants or plant parts. (hortomallas.com)
  • Understanding how physical signals guide biological processes requires qualitative and quantitative knowledge of the mechanical forces generated and sensed by cells in a physiologically realistic three-dimensional (3D) context. (princeton.edu)
  • Derived from a fundamental physical quantity (force) and a purely geometrical quantity (area), stress is also a fundamental quantity, like velocity, torque or energy, that can be quantified and analyzed without explicit consideration of the nature of the material or of its physical causes. (wikipedia.org)
  • Hand-transmitted vibrations of pneumatic grinders suspended from a mechanical arm system. (cdc.gov)
  • Mechanical stress promotes human ligamentum flavum cells (LFCs) to synthesize multitype collagens, leading to ligamentum flavum hypertrophy (LFH). (hindawi.com)
  • The lifting of an unexpectedly heavier box appeared not to lead to an increased balance loss or a clearly increased stress of the structures of the low back, although a burst of abdominal muscle activity was found in one condition. (nih.gov)
  • By doing in-vivo measurements in a hydroponic system, this study investigated the responses of unimpeded roots to local mechanical stress of their neighbouring roots. (slu.se)
  • In addition to classic dynamic mechanical analysis rheological measurements open up the possibility of characterizing the deformation behavior of solids and the flow behavior of liquids. (anton-paar.com)
  • This part 1 of a two-part series describes ground stress in mining based on measurements and observations at two western mines. (cdc.gov)
  • Chamsart, S, Hewitt, C & Nienow, A 2005, ' The impact of fluid mechanical stress on Corynebacterium glutamicum during continuous cultivation in an agitated bioreactor ', Biotechnology Letters , vol. 27, pp. 693-700. (birmingham.ac.uk)
  • Complimentary to this, fibroblasts exposed to fluid shear stress structurally rearranged pre-coated surface FN, but unstimulated and stretched cells did not. (nature.com)
  • Significant stress may exist even when deformation is negligible or non-existent (a common assumption when modeling the flow of water). (wikipedia.org)
  • Finally, 20/87 (23%) patients with normal LVEF and 27/66 (41%) of those with cardiomyopathy but without dyssynchrony based on stress indices were recategorized as having significant dyssynchrony given their resting indices. (elsevierpure.com)
  • Two Reports of Investigations provide detailed findings on ground stress redistribution resulting from mining, which could ultimately lead to significant improvements in the stability of mine excavations and ensure a safer working environment for miners. (cdc.gov)
  • Furthermore, tissue geometry defines the spatial distribution of mechanical stress across the epithelium, which communicates mechanically over distances spanning hundreds of micrometers. (princeton.edu)
  • The complete integumentary organ system (IOS) regeneration and scarless wound healing mechanism, which occurs in specific species, body sites and developmental stages, clearly shows that mechanical stress signals and immune responses play important roles in determining the wound healing mode. (mdpi.com)
  • Thus, the free surface becomes rough under the action of internal forces originated from the inhomogeneous stress-strain fields. (frontiersin.org)
  • Using this technique, we were able to obtain traction forces at the epithelium-matrix interface, and to resolve and quantify patterns of mechanical stress throughout the surrounding matrix. (princeton.edu)
  • Stress expresses the internal forces that neighbouring particles of a continuous material exert on each other, while strain is the measure of the relative deformation of the material. (wikipedia.org)
  • Stress may also be imposed on a material without the application of net forces, for example by changes in temperature or chemical composition, or by external electromagnetic fields (as in piezoelectric and magnetostrictive materials). (wikipedia.org)
  • The understanding of stress in liquids started with Newton, who provided a differential formula for friction forces (shear stress) in parallel laminar flow. (wikipedia.org)
  • The mechanical properties of copper-nickel alloys show a combination of good tensile strength and excellent ductility when annealed. (copper.org)
  • Typical annealed mechanical properties for copper-nickel alloys are given in Table 1 . (copper.org)
  • Minimum mechanical properties for 90-10 Cu-Ni (CW 352H) based on Euronorm Standards are outlined in Table 2 . (copper.org)
  • Mechanical stress testing helps determine whether a device can remain functional when subjected to sudden, abrupt motion changes associated with service environments like product handling, shipping/transportation, aerospace, weapon firing, etc. (nemko.com)
  • Ancient and medieval architects did develop some geometrical methods and simple formulas to compute the proper sizes of pillars and beams, but the scientific understanding of stress became possible only after the necessary tools were invented in the 17th and 18th centuries: Galileo Galilei's rigorous experimental method, René Descartes's coordinates and analytic geometry, and Newton's laws of motion and equilibrium and calculus of infinitesimals. (wikipedia.org)
  • Bio mechanical methods are frequently utilised together with additional therapeutic massage practices. (techdirt.stream)
  • Methods Stress/rest 82Rb gated PET was performed in consecutive patients with normal MPI between 2006 and 2010. (elsevierpure.com)
  • Shipyards and other construction and manufacturing establishments that require the extensive use of heavy powered hand tools have introduced the use of counterweighted mechanical arm systems to alleviate mechanical stressors on tool operators. (cdc.gov)
  • It has been shown that all stress and strain tensor components in the vicinity of inclusions take on non-zero values, including those directed across the load axis. (frontiersin.org)
  • On the other hand, the roughness pattern can be used for non-destructive testing of the material stress-strain state. (frontiersin.org)
  • 2. Proportional Limit is defined as the stress at which the stress strain curves begins to deviate from the straight line. (sanfoundry.com)
  • Answer:a Explanation: Proportional limit is the point of deviation in stress strain curve. (sanfoundry.com)
  • Any strain (deformation) of a solid material generates an internal elastic stress, analogous to the reaction force of a spring, that tends to restore the material to its original non-deformed state. (wikipedia.org)
  • The relation between mechanical stress, strain, and the strain rate can be quite complicated, although a linear approximation may be adequate in practice if the quantities are sufficiently small. (wikipedia.org)
  • The effect of mechanical stresses generated by an extreme agitation intensity or a high aeration rate on growth parameters and cell physiology were studied during continuous cultivation of the Gram-positive bacterium Corynebacterium glutamicum. (birmingham.ac.uk)
  • With stress gastritis, gastric acid secretion is invariably either normal or decreased. (medscape.com)
  • Mechanical stress either causes instant damage to the product or causes potential damage that may only be visible in long term. (nemko.com)
  • Mechanical damage cell models were established by scratch method, and HaCaT cells without model establishment were served as control group. (shsmu.edu.cn)
  • MCR 702e MultiDrive is the most versatile and powerful platform suitable for the dynamic mechanical analysis of solid, soft, and liquid samples. (anton-paar.com)
  • The combination of an air-bearing-supported upper rotational drive and an air-bearing-supported lower linear drive enables you to perform linear dynamic mechanical analysis using the linear drive and torsional dynamic mechanical analysis using the rotational drive. (anton-paar.com)
  • Conclusion LV mechanical dyssynchrony indices by phase analysis are smaller when derived from peak stress versus rest gated PET imaging in patients with normal MPI, irrespective of the resting LVEF. (elsevierpure.com)
  • One of the characteristic bacteria phenotypes of antibiotic resistance (and more generally of a stress response) is filamentation, which has been linked to survival strategies and virulence and is present in the most common form of bacteria in nature: biofilms. (europa.eu)
  • While the primary roots did not response to a restriction in growth of the seminal roots, seminal roots reacted to the applied stress in the same way as the impeded roots, even if the stress did not occur in their environment. (slu.se)
  • 1975). However, only recently has plant response to mechanical stress been studied to control plant. (hortomallas.com)
  • In one case they studied, chemical tags regulate the stress response to drought by closing the stomata and lengthening the primary root. (evolutionnews.org)
  • To elucidate the relationship between such mechanical stress and the development of ossification of the spinal ligaments, the authors established an animal experimental model in which the in vivo response of the spinal ligaments to direct repetitive tensile loading could be observed. (elsevierpure.com)
  • The plant response to biotic and abiotic stress has been studied for many years, but the molecular mechanism controlling touch-signalling in plants is not well understood. (lu.se)
  • Bio-Mechanical Treatment uses the wisdom and skills of the massage therapist that also makes use of therapeutic contact and assorted practices. (techdirt.stream)
  • Over several millennia, architects and builders in particular, learned how to put together carefully shaped wood beams and stone blocks to withstand, transmit, and distribute stress in the most effective manner, with ingenious devices such as the capitals, arches, cupolas, trusses and the flying buttresses of Gothic cathedrals. (wikipedia.org)
  • However, the mechanism of mechanical stress in the formation of collagen remains unclear. (hindawi.com)
  • In addition, the relationship of mechanical stress and IGF-1 in LFH as well as the potential mechanism involved was investigated. (hindawi.com)
  • Notice the mechanical word: they uncovered "how plants thrive using a natural mechanism to recycle chloroplasts. (evolutionnews.org)
  • Identifies problems with mechanical, electrical systems and executes solutions. (simplyhired.com)
  • Microleakage of four simplified adhesive systems under thermal and mechanical stresses. (bvsalud.org)
  • However, in LFH, the relationship of mechanical stress and IGF-1 has not been sufficiently studied. (hindawi.com)
  • In the case, where the roots found a way to work around the anticipated stress, they compensated for the impaired root with an increase in growth rate. (slu.se)
  • The Mechanical stress reduces plant yield applied naturally or under controlled conditions. (hortomallas.com)
  • 5. For the materials which do not exhibit a well-defined yield points, the yield strength is defined as the stress corresponding to a permanent set of how much percentage of gauge length? (sanfoundry.com)
  • What kind of mechanical stress testing does Nemko perform? (nemko.com)
  • Therefore, we investigated the relationship between mechanical stress and collagen synthesis in the present study. (hindawi.com)
  • In the present study, we hypothesized that mechanical stress plays a pivotal role in IGF-1 synthesis. (hindawi.com)
  • A study of the loading characteristics of mechanical bolts (stiffness and capacity) installed in coal ribs at five underground coal mines. (cdc.gov)
  • they are made of proteins that generate the mechanical force needed for muscles to contract. (medlineplus.gov)