A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.
A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.
A polysaccharide-producing species of STREPTOCOCCUS isolated from human dental plaque.
A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.
A bacterium which causes mastitis in cattle and occasionally in man.
Infections with bacteria of the genus STREPTOCOCCUS.
A species of STREPTOCOCCUS isolated from pigs. It is a pathogen of swine but rarely occurs in humans.
A species of gram-positive, coccoid bacteria commonly found in the alimentary tract of cows, sheep, and other ruminants. It occasionally is encountered in cases of human endocarditis. This species is nonhemolytic.
A species of gram-positive, coccoid bacteria commensal in the respiratory tract.
A species of gram-positive, coccoid bacteria isolated from abscesses in submaxillary glands and mucopurulent discharges of the upper respiratory tract of horses. This organism belongs to Group C streptococci with regards to antigen response and is known to cause strangles. The subspecies S. zooepidemicus is also considered a pathogen of horses.
A species of gram-positive, coccoid bacteria that is numerous in the mouth and throat. It is a common cause of endocarditis and is also implicated in dental plaque formation.
A species of gram-positive, coccoid bacteria isolated from the human tooth surface. Strains have been shown to be cariogenic in experimental animals and may be associated with human dental caries.
Viruses whose host is Streptococcus.
Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.
A species of gram-positive, facultatively anaerobic bacteria in the family STREPTOCOCCACEAE. It is a normal inhabitant of the human oral cavity, and causes DENTAL PLAQUE and ENDOCARDITIS. It is being investigated as a vehicle for vaccine delivery.
A species of thermophilic, gram-positive bacteria found in MILK and milk products.
Proteins found in any species of bacterium.
A species of gram-positive, coccoid bacteria commonly isolated from clinical specimens and the human intestinal tract. Most strains are nonhemolytic.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
Substances that reduce the growth or reproduction of BACTERIA.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Exotoxins produced by certain strains of streptococci, particularly those of group A (STREPTOCOCCUS PYOGENES), that cause HEMOLYSIS.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
A species of gram-positive bacteria in the STREPTOCOCCUS MILLERI GROUP. It is commonly found in the oropharynx flora and has a proclivity for abscess formation, most characteristically in the CENTRAL NERVOUS SYSTEM and LIVER.
Inflammation of the throat (PHARYNX).
Deoxyribonucleic acid that makes up the genetic material of bacteria.
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.
Substances elaborated by bacteria that have antigenic activity.
Vaccines or candidate vaccines used to prevent STREPTOCOCCAL INFECTIONS.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
Nonsusceptibility of an organism to the action of penicillins.
The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx).
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
Polysaccharides found in bacteria and in capsules thereof.
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
A species of gram-positive bacteria in the STREPTOCOCCUS MILLERI GROUP. It is commonly found in the oropharnyx flora and has a proclivity for abscess formation in the upper body and respiratory tract.
The functional hereditary units of BACTERIA.
Dextranase is an enzyme that breaks down dextran, a type of polysaccharide, into glucose.
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads.
The top portion of the pharynx situated posterior to the nose and superior to the SOFT PALATE. The nasopharynx is the posterior extension of the nasal cavities and has a respiratory function.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
A subset of VIRIDANS STREPTOCOCCI, but the species in this group differ in their hemolytic pattern and diseases caused. These species are often beta-hemolytic and produce pyogenic infections.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.
Techniques used in studying bacteria.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.
Bacteria which retain the crystal violet stain when treated by Gram's method.
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.
Substances elaborated by specific strains of bacteria that are lethal against other strains of the same or related species. They are protein or lipopolysaccharide-protein complexes used in taxonomy studies of bacteria.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.
An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.
A group of QUINOLONES with at least one fluorine atom and a piperazinyl group.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Rupture of bacterial cells due to mechanical force, chemical action, or the lytic growth of BACTERIOPHAGES.
A non-pathogenic species of LACTOCOCCUS found in DAIRY PRODUCTS and responsible for the souring of MILK and the production of LACTIC ACID.
Vaccines or candidate vaccines used to prevent infections with STREPTOCOCCUS PNEUMONIAE.
Bacterial polysaccharides that are rich in phosphodiester linkages. They are the major components of the cell walls and membranes of many bacteria.
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
The condition of harboring an infective organism without manifesting symptoms of infection. The organism must be readily transmissible to another susceptible host.
The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.
Transport proteins that carry specific substances in the blood or across cell membranes.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Polysaccharides composed of repeating glucose units. They can consist of branched or unbranched chains in any linkages.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)
Proteins isolated from the outer membrane of Gram-negative bacteria.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Esculin is a glycoside found in the cell walls of certain plants, used in medical research as a source of glucose and to study the activity of certain enzymes.
Enzymes that catalyze the transfer of an aminoacyl group from donor to acceptor resulting in the formation of an ester or amide linkage. EC 2.3.2.
An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.
Proteins that bind to particles and cells to increase susceptibility to PHAGOCYTOSIS, especially ANTIBODIES bound to EPITOPES that attach to FC RECEPTORS. COMPLEMENT C3B may also participate.
A family of gram-positive non-sporing bacteria including many parasitic, pathogenic, and saprophytic forms.
A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
A thin protein film on the surface of DENTAL ENAMEL. It is widely believed to result from the selective adsorption of precursor proteins present in SALIVA onto tooth surfaces, and to reduce microbial adherence to the TEETH.
A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The ability of bacterial cells to take up exogenous DNA and be genetically transformed by it.
Enzymes that catalyze the transfer of hexose groups. EC 2.4.1.-.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin-binding proteins are primarily enzymes involved in CELL WALL biosynthesis including MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PEPTIDE SYNTHASES; TRANSPEPTIDASES; and HEXOSYLTRANSFERASES.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
A febrile disease occurring as a delayed sequela of infections with STREPTOCOCCUS PYOGENES. It is characterized by multiple focal inflammatory lesions of the connective tissue structures, such as the heart, blood vessels, and joints (POLYARTHRITIS) and brain, and by the presence of ASCHOFF BODIES in the myocardium and skin.
Semisynthetic broad-spectrum cephalosporin.
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.
Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.
A fulminating bacterial infection of the deep layers of the skin and FASCIA. It can be caused by many different organisms, with STREPTOCOCCUS PYOGENES being the most common.
Ribonucleic acid in bacteria having regulatory and catalytic roles as well as involvement in protein synthesis.
INFLAMMATION of the UDDER in cows.
Gram-negative aerobic cocci of low virulence that colonize the nasopharynx and occasionally cause MENINGITIS; BACTEREMIA; EMPYEMA; PERICARDITIS; and PNEUMONIA.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
A genus of gram-negative, anaerobic cocci parasitic in the mouth and in the intestinal and respiratory tracts of man and other animals.
The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)
A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
A genus of gram-positive, microaerophilic, rod-shaped bacteria occurring widely in nature. Its species are also part of the many normal flora of the mouth, intestinal tract, and vagina of many mammals, including humans. Pathogenicity from this genus is rare.
Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)
Skin diseases caused by bacteria.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
A natural association between organisms that is detrimental to at least one of them. This often refers to the production of chemicals by one microorganism that is harmful to another.
The relationships of groups of organisms as reflected by their genetic makeup.
Substances, usually of biological origin, that cause cells or other organic particles to aggregate and stick to each other. They include those ANTIBODIES which cause aggregation or agglutination of particulate or insoluble ANTIGENS.
The L-isomer of Ofloxacin.
A property of the surface of an object that makes it stick to another surface.
The genetic complement of a BACTERIA as represented in its DNA.
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Coccus-shaped bacteria that retain the crystal violet stain when treated by Gram's method.
Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
Naphthyridines are a class of heterocyclic compounds with a naphthalene ring fused to a pyridine ring, with potential applications in the medical field as drugs and dyes.
Bacterial variants, unable to form a complete cell wall, which are formed in cultures by various bacteria; granules (L bodies) appear, unite, and grow into amorphous bodies which multiply and give rise to bacterial cells morphologically indistinguishable from the parent strain.
Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTIGEN injection or infection with microorganisms containing the antigen.
Infections by bacteria, general or unspecified.
Nonsusceptibility of bacteria to the action of TETRACYCLINE which inhibits aminoacyl-tRNA binding to the 30S ribosomal subunit during protein synthesis.
The clumping together of suspended material resulting from the action of AGGLUTININS.
A common superficial bacterial infection caused by STAPHYLOCOCCUS AUREUS or group A beta-hemolytic streptococci. Characteristics include pustular lesions that rupture and discharge a thin, amber-colored fluid that dries and forms a crust. This condition is commonly located on the face, especially about the mouth and nose.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.
Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
A diet that contributes to the development and advancement of DENTAL CARIES.
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
A genus of gram-positive, coccoid bacteria consisting of organisms causing variable hemolysis that are normal flora of the intestinal tract. Previously thought to be a member of the genus STREPTOCOCCUS, it is now recognized as a separate genus.
Enzyme which catalyzes the peptide cross-linking of nascent CELL WALL; PEPTIDOGLYCAN.
Diseases of domestic swine and of the wild boar of the genus Sus.
Infection with group A streptococci that is characterized by tonsillitis and pharyngitis. An erythematous rash is commonly present.
Acyltransferases that use AMINO ACYL TRNA as the amino acid donor in formation of a peptide bond. There are ribosomal and non-ribosomal peptidyltransferases.
An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
An infant during the first month after birth.
Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.
The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of ADENYLYL CYCLASES. EC 2.7.1.-.
Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
Peptidoglycan is a complex polymer found in the cell walls of bacteria, composed of sugars and amino acids, that provides structural support and protection against external stresses.
Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
Aerobic bacteria are microorganisms that require oxygen to survive and carry out metabolic processes.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).
Aza compounds are a class of organic compounds containing a nitrogen atom bonded to a carbon atom, with potential applications in the medical field.
Ability of a microbe to survive under given conditions. This can also be related to a colony's ability to replicate.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.
A broad-spectrum antimicrobial carboxyfluoroquinoline.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.
One of a set of bone-like structures in the mouth used for biting and chewing.
ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.
An acute infection of the skin caused by species of STREPTOCOCCUS. This disease most frequently affects infants, young children, and the elderly. Characteristics include pink-to-red lesions that spread rapidly and are warm to the touch. The commonest site of involvement is the face.
The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Genomes of temperate BACTERIOPHAGES integrated into the DNA of their bacterial host cell. The prophages can be duplicated for many cell generations until some stimulus induces its activation and virulence.
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed)
Pyruvate oxidase is an enzyme that catalyzes the oxidation of pyruvate to acetyl-CoA, carbon dioxide, and water in the mitochondria of cells.
The white liquid secreted by the mammary glands. It contains proteins, sugar, lipids, vitamins, and minerals.
Any purulent skin disease (Dorland, 27th ed).
A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.
The spontaneous disintegration of tissues or cells by the action of their own autogenous enzymes.
The complete absence, or (loosely) the paucity, of gaseous or dissolved elemental oxygen in a given place or environment. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of PHOSPHORYLASES. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the HEXOSYLTRANSFERASES; PENTOSYLTRANSFERASES; SIALYLTRANSFERASES; and those transferring other glycosyl groups. EC 2.4.
The sum of the weight of all the atoms in a molecule.
Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.

Interaction of inflammatory cells and oral microorganisms. II. Modulation of rabbit polymorphonuclear leukocyte hydrolase release by polysaccharides in response to Streptococcus mutans and Streptococcus sanguis. (1/4020)

The release of lysosomal hydrolases from polymorphonuclear leukocytes (PMNs) has been postulated in the pathogenesis of tissue injury in periodontal disease. In the present study, lysosomal enzyme release was monitored from rabbit peritoneal exudate PMNs exposed to Streptocccus mutans or Streptococcus sanguis. S. mutans grown in brain heart infusion (BHI) broth failed to promote significant PMN enzyme release. S. sanguis grown in BHI broth, although more effective than S. mutants, was a weak stimulus for promotion of PMN hydrolase release. Preincubation of washed, viable S. mutans in sucrose or in different-molecular-weight dextrans resulted in the ability of the organisms to provoke PMN release reactions. This effect could bot be demonstrated with boiled or trypsinized S. mutans or with viable S. sanguis. However, when grown in BHI broth supplemented with sucrose, but not with glucose, both S. mutans and S. sanguis triggered discharge of PMN enzymes. The mechanism(s) whereby dextran or sucrose modulates PMN-bacterial interaction may in some manner be related to promotion of microbial adhesiveness or aggregation by dextran and by bacterial synthesis of glucans from sucrose.  (+info)

Interaction of inflammatory cells and oral microorganisms. III. Modulation of rabbit polymorphonuclear leukocyte hydrolase release response to Actinomyces viscosus and Streptococcus mutans by immunoglobulins and complement. (2/4020)

In the absence of antiserum, rabbit polymorphonuclear leukocytes (PMNs) released lysosomal enzymes in response to Actinomyces viscosus (19246) but not to Streptococcus mutans (6715). Antibodies had a marked modulating influence on these reactions. PMN hydrolase release was significantly enhanced to both organisms when specific rabbit antiserum and isolated immunoglobulin G (IgG) were included in the incubations. Immune complex F(ab')2 fragments of IgG directed against S. mutans agglutinated bacteria. Immune complexes consisting of S. mutans and F(ab')2 fragments of IgG directed against this organism were not effective as bacteria-IgG complexes in stimulating PMN release. The intensity of the release response to bacteria-IgG complexes was also diminished when PMNs were preincubated with isolated Fc fragments derived from IgG. Fresh serum as a source of complement components had no demonstrable effect on PMN release either alone or in conjuction with antiserum in these experiments. These data may be relevant to the mechanisms and consequences of the interaction of PMNs and plaque bacteria in the pathogenesis of periodontal disease.  (+info)

Purification and cloning of a streptokinase from Streptococcus uberis. (3/4020)

A bovine plasminogen activator was purified from the culture supernatant of the bovine pathogen Streptococcus uberis NCTC 3858. After the final reverse-phase high-performance liquid chromatography step a single protein with a molecular mass of 32 kDa was detected in the active fraction. A partial peptide map was established, and degenerate primers were designed and used for amplification of fragments of the gene encoding the activator. Inverse PCR was subsequently used for obtaining the full-length gene. The S. uberis plasminogen activator gene (skc) encodes a protein consisting of 286 amino acids including a signal peptide of 25 amino acids. In an amino acid sequence comparison the cloned activator showed an identity of approximately 26% to the streptokinases isolated from Streptococcus equisimilis and Streptococcus pyogenes. Interestingly, the activator from S. uberis was found to lack the C-terminal domain possessed by the streptokinase from S. equisimilis. This is apparently a general feature of the streptokinases of this species; biochemical and genetic analysis of 10 additional strains of S. uberis revealed that 9 of these were highly similar to strain NCTC 3858. Sequencing of the skc gene from three of these strains indicated that the amino acid sequence of the protein is highly conserved within the species.  (+info)

Surface expression of a protective recombinant pertussis toxin S1 subunit fragment in Streptococcus gordonii. (4/4020)

In this study, the expression of the Bordetella pertussis S1 subunit was tested in Streptococcus gordonii, a commensal oral bacterium which has the potential to be a live oral vaccine vehicle. The DNA fragment encoding the N-terminal 179 amino acids of the S1 subunit was ligated into the middle part of spaP, the surface protein antigen P1 gene originating from Streptococcus mutans. The resulting construct, carried on the Escherichia coli-Streptococcus shuttle vector pDL276, was introduced into S. gordonii DL-1 by natural transformation. One of the transformants (RJMIII) produced a 187-kDa protein (the predicted size of the SpaP-S1 fusion protein) which was recognized by both the anti-pertussis toxin (anti-PT) and anti-SpaP antibodies, suggesting that an in-frame fusion had been made. Results from immunogold-electron microscopic studies and cellular fractionation studies showed that the fusion protein was surface localized and was mainly associated with the cell wall of RJMIII, indicating that SpaP was able to direct the fusion protein to the cell surface. A rabbit antiserum raised against heat-killed S. gordonii RJMIII recognized the native S1 subunit of PT in Western blotting and showed a weak neutralization titer to PT by the Chinese hamster ovary cell-clustering assay. BALB/c mice immunized with the heat-killed S. gordonii RJMIII were protected from the toxic effect of PT in the leukocytosis-promoting and histamine sensitization assays. In conclusion, a fragment of the S1 subunit of PT was successfully surface expressed in S. gordonii; the recombinant S1 fragment was found to be immunogenic and could induce protection against the toxic effect of PT in mice.  (+info)

The influence of a diet rich in wheat fibre on the human faecal flora. (5/4020)

The effect on the faecal flora of adding wheat fibre to a controlled diet in four healthy volunteers for a 3-week period has been observed. No change in the concentration of the bacteria in the bacterial groups counted was found, although there was a slight increase in total output associated with increased faecal weight. The predominant organisms in all subjects were non-sporing anaerobes, but the dominant species in each subject was different and was unaffected by changing the diet. Similarly, the concentration of faecal beta-glucuronidase detected in two subjects was unaltered and the concentration of clostridia able to dehydrogenate the steroid nucleus found in one subject was unaltered. It is suggested that the faecal microflora is not primarily controlled by the presence of undigested food residues in the large bowel.  (+info)

Humoral immunity to commensal oral bacteria in human infants: salivary secretory immunoglobulin A antibodies reactive with Streptococcus mitis biovar 1, Streptococcus oralis, Streptococcus mutans, and Enterococcus faecalis during the first two years of life. (6/4020)

Secretory immunoglobulin A (SIgA) antibodies reactive with the pioneer oral streptococci Streptococcus mitis biovar 1 and Streptococcus oralis, the late oral colonizer Streptococcus mutans, and the pioneer enteric bacterium Enterococcus faecalis in saliva samples from 10 human infants from birth to age 2 years were analyzed. Low levels of salivary SIgA1 and SIgA2 antibodies reactive with whole cells of all four species were detected within the first month after birth, even though S. mutans and E. faecalis were not recovered from the mouths of the infants during the study period. Although there was a fivefold increase in the concentration of SIgA between birth and age 2 years, there were no differences between the concentrations of SIgA1 and SIgA2 antibodies reactive with the four species over this time period. When the concentrations of SIgA1 and SIgA2 antibodies reactive with all four species were normalized to the concentrations of SIgA1 and SIgA2 in saliva, SIgA1 and SIgA2 antibodies reactive with these bacteria showed a significant decrease from birth to 2 years of age. Adsorption of each infant's saliva with cells of one species produced a dramatic reduction of antibodies recognizing the other three species. Sequential adsorption of saliva samples removed all SIgA antibody to the bacteria, indicating that the SIgA antibodies were directed to antigens shared by all four species. The induction by the host of a limited immune response to common antigens that are likely not involved in adherence may be among the mechanisms that commensal streptococci employ to persist in the oral cavity.  (+info)

Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. (7/4020)

Netilmicin (Sch 20569) is a new broad-spectrum semisynthetic aminoglycoside derived from sisomicin. Netilmicin was compared to gentamicin, tobramycin, and amikacin in a variety of in vitro test systems as well as in mouse protection tests. Netilmicin was found to be similar in activity to gentamicin against aminoglycoside-susceptible strains in both in vitro and in vivo tests. Netilmicin was also active against many aminoglycoside-resistant strains of gram-negative bacteria, particularly those known to possess adenylating enzymes (ANT 2') or those with a similar resistance pattern. Netilmicin was found to be markedly less toxic than gentamicin in chronic studies in cats, although gentamicin appeared less toxic in acute toxicity tests in mice. The concentrations of netilmicin and gentamicin in serum were compared in dogs after intramuscular dosing, and the pharmacokinetics including peak concentrations in serum were found to be similar.  (+info)

Isolation of an active catalytic core of Streptococcus downei MFe28 GTF-I glucosyltransferase. (8/4020)

Truncated variants of GTF-I from Streptococcus downei MFe28 were purified by means of a histidine tag. Sequential deletions showed that the C-terminal domain was not directly involved in the catalytic process but was required for primer activation. A fully active catalytic core of only 100 kDa was isolated.  (+info)

Streptococcal infections are a group of illnesses caused by bacteria of the genus Streptococcus. These bacteria can cause a wide range of infections, including throat infections (strep throat), skin infections (impetigo), ear infections, and pneumonia. Streptococcal infections are typically spread through contact with infected individuals or contaminated surfaces, and they can be treated with antibiotics. Some types of streptococcal infections can also cause more serious complications, such as rheumatic fever and post-streptococcal glomerulonephritis, which can damage the kidneys.

Pneumococcal infections are a group of illnesses caused by the bacterium Streptococcus pneumoniae. These infections can affect various parts of the body, including the lungs, sinuses, ears, bloodstream, and brain. The most common type of pneumococcal infection is pneumonia, which is an inflammation of the lungs caused by bacteria. Other types of pneumococcal infections include meningitis (inflammation of the lining of the brain and spinal cord), otitis media (middle ear infection), sinusitis (sinus infection), and bacteremia (presence of bacteria in the bloodstream). Pneumococcal infections can be serious, especially in people with weakened immune systems, such as young children, older adults, and people with chronic medical conditions. Vaccines are available to prevent some types of pneumococcal infections, and antibiotics are used to treat them.

Bacterial proteins are proteins that are synthesized by bacteria. They are essential for the survival and function of bacteria, and play a variety of roles in bacterial metabolism, growth, and pathogenicity. Bacterial proteins can be classified into several categories based on their function, including structural proteins, metabolic enzymes, regulatory proteins, and toxins. Structural proteins provide support and shape to the bacterial cell, while metabolic enzymes are involved in the breakdown of nutrients and the synthesis of new molecules. Regulatory proteins control the expression of other genes, and toxins can cause damage to host cells and tissues. Bacterial proteins are of interest in the medical field because they can be used as targets for the development of antibiotics and other antimicrobial agents. They can also be used as diagnostic markers for bacterial infections, and as vaccines to prevent bacterial diseases. Additionally, some bacterial proteins have been shown to have therapeutic potential, such as enzymes that can break down harmful substances in the body or proteins that can stimulate the immune system.

Anti-bacterial agents, also known as antibiotics, are medications that are used to treat bacterial infections. They work by killing or inhibiting the growth of bacteria, thereby preventing the spread of the infection. There are several types of anti-bacterial agents, including: 1. Penicillins: These are the first antibiotics discovered and are effective against a wide range of bacteria. 2. Cephalosporins: These are similar to penicillins and are effective against many of the same types of bacteria. 3. Macrolides: These antibiotics are effective against bacteria that are resistant to other antibiotics. 4. Tetracyclines: These antibiotics are effective against a wide range of bacteria and are often used to treat acne. 5. Fluoroquinolones: These antibiotics are effective against a wide range of bacteria and are often used to treat respiratory infections. It is important to note that antibiotics are only effective against bacterial infections and are not effective against viral infections such as the common cold or flu. Additionally, overuse or misuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which can be more difficult to treat.

Streptolysins are a group of enzymes produced by certain strains of the bacterium Streptococcus pyogenes (also known as Group A Streptococcus or GAS). These enzymes are capable of breaking down the cell walls of other bacteria, which can lead to the lysis (rupture) of the bacterial cells. Streptolysins are classified into two main types: Streptolysin O (SLO) and Streptolysin S (SLS). SLO is the more common of the two and is responsible for the majority of the lysis caused by GAS. SLS is less common and is thought to play a role in the invasion of host cells by GAS. Streptolysins are important virulence factors for GAS, meaning they contribute to the ability of the bacteria to cause disease. They are thought to play a role in the pathogenesis of a variety of GAS infections, including strep throat, scarlet fever, and necrotizing fasciitis (a severe skin infection). In addition, streptolysins have been shown to have potential therapeutic applications, such as in the treatment of bacterial infections and as adjuvants in vaccines.

Pharyngitis is a medical condition characterized by inflammation of the pharynx, which is the back of the throat. It can be caused by a viral or bacterial infection, allergies, irritants, or other factors. Symptoms of pharyngitis may include sore throat, difficulty swallowing, fever, cough, and headache. In some cases, pharyngitis may be accompanied by tonsillitis, which is inflammation of the tonsils located at the back of the throat. Treatment for pharyngitis depends on the underlying cause and may include medications such as antibiotics, antiviral drugs, or over-the-counter pain relievers. In some cases, rest and hydration may be sufficient to help the body fight off the infection.

DNA, Bacterial refers to the genetic material of bacteria, which is a type of single-celled microorganism that can be found in various environments, including soil, water, and the human body. Bacterial DNA is typically circular in shape and contains genes that encode for the proteins necessary for the bacteria to survive and reproduce. In the medical field, bacterial DNA is often studied as a means of identifying and diagnosing bacterial infections. Bacterial DNA can be extracted from samples such as blood, urine, or sputum and analyzed using techniques such as polymerase chain reaction (PCR) or DNA sequencing. This information can be used to identify the specific type of bacteria causing an infection and to determine the most effective treatment. Bacterial DNA can also be used in research to study the evolution and diversity of bacteria, as well as their interactions with other organisms and the environment. Additionally, bacterial DNA can be modified or manipulated to create genetically engineered bacteria with specific properties, such as the ability to produce certain drugs or to degrade pollutants.

Dental plaque is a sticky, colorless film that forms on teeth and gums. It is made up of bacteria, food particles, saliva, and other substances. Plaque is constantly forming on teeth, but it can be removed by brushing and flossing regularly. If plaque is not removed, it can harden into tartar, which can cause gum disease and tooth decay. In the medical field, dental plaque is an important factor in maintaining oral health and preventing dental problems.

Erythromycin is a broad-spectrum antibiotic that is commonly used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted infections. It works by inhibiting the growth of bacteria by interfering with their ability to make proteins, which are essential for their survival. Erythromycin is available in various forms, including tablets, capsules, and liquid suspensions. It is usually taken orally, although it can also be given intravenously in severe cases. It is important to note that erythromycin may not be effective against all types of bacteria, and it can also cause side effects such as nausea, diarrhea, and allergic reactions. Therefore, it is important to use erythromycin only as directed by a healthcare professional and to complete the full course of treatment, even if symptoms improve before the medication is finished.

Pneumonia, Pneumococcal is a type of pneumonia caused by the bacterium Streptococcus pneumoniae. It is a common respiratory infection that can affect people of all ages, but it is most common in children, older adults, and people with weakened immune systems. The symptoms of pneumococcal pneumonia can include fever, cough, chest pain, difficulty breathing, and fatigue. In severe cases, it can lead to complications such as sepsis, meningitis, and pneumonia-related death. Pneumococcal pneumonia can be treated with antibiotics, but it is important to seek medical attention promptly if you suspect you or someone you know may have this infection. Vaccines are also available to prevent pneumococcal pneumonia, and they are recommended for certain high-risk groups such as children, older adults, and people with certain medical conditions.

In the medical field, "Antigens, Bacterial" refers to substances that are produced by bacteria and can trigger an immune response in the body. These antigens can be proteins, polysaccharides, lipids, or nucleic acids that are unique to a particular bacterial species or strain. When bacteria enter the body, the immune system recognizes these antigens as foreign and mounts a defense against them. This response can include the production of antibodies by B cells, which can neutralize the bacteria or mark them for destruction by other immune cells. The immune response to bacterial antigens is an important part of the body's defense against bacterial infections. Bacterial antigens are used in a variety of medical applications, including the development of vaccines to prevent bacterial infections. By introducing a small amount of a bacterial antigen into the body, vaccines can stimulate the immune system to produce a response that will protect against future infections by the same bacteria.

Streptococcal vaccines are vaccines that are designed to protect against infections caused by Streptococcus bacteria. Streptococcus bacteria are a group of Gram-positive bacteria that can cause a variety of infections, including strep throat, scarlet fever, and pneumonia. There are several different types of streptococcal vaccines that have been developed, including vaccines that target specific types of Streptococcus bacteria, such as Streptococcus pneumoniae and Streptococcus pyogenes. These vaccines are typically given to people who are at high risk of developing streptococcal infections, such as young children, older adults, and people with certain medical conditions. Streptococcal vaccines work by stimulating the body's immune system to produce antibodies that can recognize and fight off Streptococcus bacteria. This can help to prevent the bacteria from causing infections, or can help to reduce the severity and duration of infections if they do occur. It is important to note that streptococcal vaccines are not a cure for streptococcal infections, and they may not be effective in everyone. However, they can be an important tool in preventing and controlling the spread of these infections.

Bacterial adhesion refers to the process by which bacteria attach themselves to a surface, such as a host tissue or medical device. This process is a critical step in the colonization and infection of a host by bacteria. Bacterial adhesion is facilitated by the presence of adhesins, which are proteins on the surface of bacteria that interact with specific receptors on the host surface. These interactions can be either reversible or irreversible, depending on the strength of the bond between the adhesin and receptor. Bacterial adhesion can have important implications in the medical field, particularly in the context of infections. For example, the ability of bacteria to adhere to medical devices can lead to biofilm formation, which can make infections more difficult to treat. Additionally, bacterial adhesion to host tissues can contribute to the development of chronic infections and tissue damage. Understanding the mechanisms of bacterial adhesion is therefore important for the development of new strategies to prevent and treat bacterial infections.

Bacterial capsules are a protective layer that surrounds the cell wall of certain bacteria. The capsule is composed of polysaccharides, which are complex carbohydrates that provide a physical barrier against the host's immune system and other environmental stresses. The presence of a capsule can have significant implications for the pathogenicity of bacteria. Capsules can help bacteria evade the host's immune system by preventing antibodies and immune cells from binding to the bacterial surface. They can also help bacteria resist phagocytosis, a process by which immune cells engulf and destroy bacteria. Bacterial capsules are commonly found in pathogenic bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. They are also found in some non-pathogenic bacteria, such as Escherichia coli and Salmonella. In the medical field, the presence of bacterial capsules is often studied in the context of infectious diseases. Understanding the role of bacterial capsules in pathogenesis can help researchers develop new strategies for preventing and treating infections caused by these bacteria.

Dental caries, also known as tooth decay, is a common dental disease that affects the hard tissues of the teeth, including the enamel, dentin, and pulp. It is caused by the demineralization of tooth enamel due to the production of acid by bacteria in the mouth. The bacteria in the mouth feed on sugars and starches in the food we eat, producing acid as a byproduct. This acid can erode the enamel on the teeth, leading to the formation of cavities. If left untreated, dental caries can progress and cause damage to the underlying dentin and pulp, leading to pain, infection, and tooth loss. Dental caries is a preventable disease through good oral hygiene practices, such as brushing and flossing regularly, using fluoride toothpaste and mouthwash, and limiting sugary and acidic foods and drinks. Early detection and treatment of dental caries can help prevent more serious complications and maintain good oral health.

Polysaccharides, bacterial are complex carbohydrates that are produced by bacteria. They are composed of long chains of sugar molecules and can be found in the cell walls of many bacterial species. Some common examples of bacterial polysaccharides include peptidoglycan, lipopolysaccharide, and teichoic acid. These molecules play important roles in the structure and function of bacterial cells, and they can also have medical significance. For example, lipopolysaccharide is a component of the outer membrane of certain gram-negative bacteria and can trigger an immune response in the body. In some cases, bacterial polysaccharides can also be used as vaccines to protect against bacterial infections.

Penicillins are a group of antibiotics that are derived from the Penicillium fungi. They are one of the most widely used antibiotics in the medical field and are effective against a variety of bacterial infections, including pneumonia, strep throat, and urinary tract infections. Penicillins work by inhibiting the production of cell walls in bacteria, which causes the bacteria to burst and die. There are several different types of penicillins, including penicillin G, penicillin V, amoxicillin, and cephalosporins, which have different properties and are used to treat different types of infections. Penicillins are generally well-tolerated by most people, but can cause side effects such as allergic reactions, diarrhea, and nausea. It is important to take penicillins exactly as prescribed by a healthcare provider and to finish the full course of treatment, even if symptoms improve before the medication is finished.

Dextranase is an enzyme that breaks down dextran, a type of polysaccharide found in certain bacteria and fungi. In the medical field, dextranase is used as a medication to treat certain types of infections caused by bacteria or fungi that produce dextran. It works by breaking down the dextran produced by these microorganisms, which can help to prevent them from forming biofilms and causing infections. Dextranase is typically administered intravenously and is used to treat infections of the respiratory tract, urinary tract, and skin and soft tissues. It may also be used to treat certain types of cancer and to prevent blood clots.

Glucosyltransferases are a group of enzymes that transfer glucose molecules from a donor substrate to an acceptor substrate. These enzymes play important roles in various biological processes, including the synthesis of complex carbohydrates, glycosylation of proteins and lipids, and the metabolism of drugs and toxins. In the medical field, glucosyltransferases are often studied in the context of diseases such as cancer, diabetes, and inflammatory disorders. For example, certain types of cancer cells overexpress specific glucosyltransferases, which can contribute to the growth and spread of the tumor. Similarly, changes in the activity of glucosyltransferases have been implicated in the development of diabetes and other metabolic disorders. In addition, glucosyltransferases are also important targets for drug development. For example, inhibitors of specific glucosyltransferases have been shown to have anti-cancer and anti-inflammatory effects, and are being investigated as potential therapeutic agents.

In the medical field, culture media refers to a nutrient-rich substance used to support the growth and reproduction of microorganisms, such as bacteria, fungi, and viruses. Culture media is typically used in diagnostic laboratories to isolate and identify microorganisms from clinical samples, such as blood, urine, or sputum. Culture media can be classified into two main types: solid and liquid. Solid media is usually a gel-like substance that allows microorganisms to grow in a three-dimensional matrix, while liquid media is a broth or solution that provides nutrients for microorganisms to grow in suspension. The composition of culture media varies depending on the type of microorganism being cultured and the specific needs of that organism. Culture media may contain a variety of nutrients, including amino acids, sugars, vitamins, and minerals, as well as antibiotics or other agents to inhibit the growth of unwanted microorganisms. Overall, culture media is an essential tool in the diagnosis and treatment of infectious diseases, as it allows healthcare professionals to identify the specific microorganisms causing an infection and select the most appropriate treatment.

Actinomyces is a genus of gram-positive bacteria that are commonly found in the human mouth, gut, and skin. They are known to be part of the normal flora of the oral cavity and are often present in dental plaque. However, some species of Actinomyces can cause infections, particularly in the oral cavity and respiratory tract. Actinomyces infections are typically chronic and can be difficult to diagnose and treat. They can cause a range of symptoms, including swelling, pain, and discharge from the affected area. Infections can also spread to other parts of the body, such as the brain, bones, and joints. Actinomyces infections are usually treated with antibiotics, although the specific treatment depends on the type and severity of the infection. In some cases, surgery may be necessary to remove infected tissue or drain abscesses. It is important to seek medical attention if you suspect you have an Actinomyces infection, as prompt treatment can help prevent complications and improve outcomes.

Macrolides are a class of antibiotics that are commonly used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted infections. They work by inhibiting the production of proteins that are essential for the growth and reproduction of bacteria. Macrolides are typically administered orally or intravenously, and they have a broad spectrum of activity against many different types of bacteria. Some common examples of macrolides include erythromycin, azithromycin, and clarithromycin. Macrolides are generally considered to be safe and effective, although they can cause side effects such as nausea, diarrhea, and stomach pain. They may also interact with other medications, so it is important to inform your healthcare provider of all the medications you are taking before starting treatment with a macrolide.

Antibodies, Bacterial are proteins produced by the immune system in response to bacterial infections. They are also known as bacterial antibodies or bacterial immunoglobulins. These antibodies are specific to bacterial antigens, which are molecules found on the surface of bacteria that trigger an immune response. When the immune system detects a bacterial infection, it produces antibodies that bind to the bacterial antigens and mark them for destruction by other immune cells. This helps to neutralize the bacteria and prevent them from causing harm to the body. Bacterial antibodies can be detected in the blood or other bodily fluids using laboratory tests. These tests are often used to diagnose bacterial infections and to monitor the effectiveness of antibiotic treatments.

Adhesins are proteins found on the surface of certain bacteria that allow them to adhere to and colonize host cells or tissues. These proteins play a crucial role in the pathogenesis of many bacterial infections, as they enable bacteria to attach to and invade host cells, resist phagocytosis by immune cells, and form biofilms that can protect bacteria from antibiotics and the host immune system. Adhesins are typically classified based on their function and the type of host cell or tissue they bind to. For example, some adhesins are involved in the attachment of bacteria to epithelial cells lining the respiratory, gastrointestinal, or urinary tracts, while others bind to blood cells or the extracellular matrix. The study of adhesins is an important area of research in the medical field, as it can help identify new targets for the development of antibiotics and vaccines, as well as provide insights into the mechanisms of bacterial pathogenesis and the development of antibiotic resistance.

Bacteriological techniques refer to the methods and procedures used to study and manipulate bacteria in the medical field. These techniques are used to identify, isolate, and culture bacteria, as well as to study their characteristics, behavior, and interactions with other microorganisms and the environment. Some common bacteriological techniques used in the medical field include: 1. Culture and isolation: This involves growing bacteria in a controlled environment, such as a petri dish or broth, to study their growth and behavior. 2. Identification: This involves using various methods, such as Gram staining, biochemical tests, and molecular techniques, to identify specific bacterial species. 3. Antibiotic susceptibility testing: This involves testing bacteria to determine their sensitivity to different antibiotics, which can help guide the selection of appropriate antibiotics for treatment. 4. Molecular techniques: These include techniques such as polymerase chain reaction (PCR) and DNA sequencing, which are used to study bacterial genetics and identify specific bacterial strains. 5. Immunological techniques: These include techniques such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence, which are used to detect and quantify specific bacterial antigens or antibodies in biological samples. Overall, bacteriological techniques play a critical role in the diagnosis, treatment, and prevention of bacterial infections and diseases in the medical field.

Endocarditis, bacterial is an infection of the inner lining of the heart (endocardium) and the heart valves. It is caused by bacteria that enter the bloodstream and attach themselves to the heart valves or other areas of the heart. The infection can cause inflammation, damage to the heart valves, and the formation of scar tissue, which can lead to heart failure or other complications. Bacterial endocarditis is typically treated with antibiotics, but surgery may be necessary in some cases to repair or replace damaged heart valves. It is a serious condition that requires prompt medical attention.

Meningitis, Pneumococcal is a serious bacterial infection that affects the protective membranes covering the brain and spinal cord. It is caused by the bacterium Streptococcus pneumoniae, also known as pneumococcus. The infection can cause inflammation and swelling of the meninges, leading to symptoms such as severe headache, fever, neck stiffness, sensitivity to light, and vomiting. In severe cases, meningitis can lead to complications such as brain damage, hearing loss, seizures, and even death. Pneumococcal meningitis is typically treated with antibiotics, which are given intravenously to quickly eliminate the bacteria from the body. In some cases, additional supportive care may be necessary to manage symptoms and prevent complications. Prevention of pneumococcal meningitis is also important, and can be achieved through vaccination. The pneumococcal conjugate vaccine (PCV13) is recommended for infants and young children, while the pneumococcal polysaccharide vaccine (PPSV23) is recommended for older adults and individuals with certain medical conditions.

Anti-infective agents, also known as antimicrobial agents, are drugs that are used to treat infections caused by microorganisms such as bacteria, viruses, fungi, and parasites. These agents work by either killing the microorganisms or inhibiting their growth and reproduction. There are several types of anti-infective agents, including antibiotics, antiviral drugs, antifungal drugs, and antiparasitic drugs. Antibiotics are the most commonly used anti-infective agents and are used to treat bacterial infections. Antiviral drugs are used to treat viral infections, while antifungal drugs are used to treat fungal infections. Antiparasitic drugs are used to treat parasitic infections. The use of anti-infective agents is an important part of modern medicine, as they are essential for treating a wide range of infections and preventing the spread of infectious diseases. However, the overuse and misuse of these agents can lead to the development of antibiotic-resistant bacteria, which can be difficult to treat and can pose a serious threat to public health.

Biofilms are complex communities of microorganisms that adhere to surfaces and are embedded in a self-produced extracellular matrix. In the medical field, biofilms are often associated with chronic infections that are difficult to treat with antibiotics. Biofilms can form on medical devices such as catheters, prosthetic joints, and dental implants, as well as on the surfaces of the human body. The bacteria in a biofilm are more resistant to antibiotics and the immune system than bacteria in a planktonic state, making them a significant challenge in the treatment of infections.

Meningitis, bacterial is an infection of the protective membranes covering the brain and spinal cord, known as the meninges. It is caused by bacteria, most commonly Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b (Hib). The symptoms of bacterial meningitis can include fever, headache, neck stiffness, sensitivity to light, vomiting, and a rash. In severe cases, it can lead to seizures, confusion, and even coma or death if not treated promptly. Bacterial meningitis is a medical emergency and requires prompt diagnosis and treatment with antibiotics. Vaccines are available to prevent some types of bacterial meningitis, including Hib and meningococcal meningitis.

Bacteriocins are small proteins produced by bacteria that have the ability to inhibit the growth of other bacteria. They are often referred to as "bacterial antibiotics" because they can be used to control the growth of harmful bacteria in a variety of settings, including in the human body. Bacteriocins are produced by a wide range of bacteria, including many that are commonly found in the human gut. They are typically active against specific types of bacteria, and are not effective against viruses or fungi. Bacteriocins work by targeting specific components of bacterial cells, such as the cell wall or membrane. They can also interfere with the bacteria's ability to reproduce or communicate with other bacteria. Bacteriocins have been studied for their potential use as natural antibiotics, and some have been approved for use in food preservation and as a treatment for certain infections. However, more research is needed to fully understand their potential uses and to develop effective ways of delivering them to the body.

Bacterial typing techniques are methods used to identify and classify bacteria based on their characteristics, such as their shape, size, and genetic makeup. These techniques are important in the medical field because they help healthcare professionals to identify the specific type of bacteria causing an infection and to determine the most effective treatment for that infection. There are several different bacterial typing techniques, including: 1. Serotyping: This technique involves identifying the specific proteins on the surface of bacteria, called antigens, which can be used to distinguish one strain of bacteria from another. 2. Pulsed-field gel electrophoresis (PFGE): This technique involves separating bacterial DNA into fragments of different sizes using an electric field, and then comparing the patterns of these fragments to determine the genetic relatedness of different strains of bacteria. 3. Multilocus sequence typing (MLST): This technique involves sequencing specific regions of bacterial DNA and comparing the sequences to determine the genetic relatedness of different strains of bacteria. 4. Antibiotic susceptibility testing: This technique involves testing bacteria to determine their sensitivity to different antibiotics, which can help healthcare professionals to choose the most effective treatment for a particular infection. Overall, bacterial typing techniques are important tools in the diagnosis and treatment of bacterial infections, and they play a critical role in the development of new antibiotics and other treatments for bacterial diseases.

N-Acetylmuramoyl-L-alanine amidase (also known as muramidase or muramidase amidohydrolase) is an enzyme that plays a crucial role in the metabolism of bacterial cell walls. It is responsible for cleaving the peptide bond between N-acetylmuramoyl-L-alanine and N-acetylglucosamine in peptidoglycan, a major component of bacterial cell walls. The enzyme is produced by bacteria and is activated by the presence of calcium ions. It is also found in some fungi and archaea, but not in eukaryotic cells. In the medical field, N-acetylmuramoyl-L-alanine amidase is used as a diagnostic tool to detect bacterial infections. It is also being studied as a potential target for the development of new antibiotics, as inhibition of the enzyme can disrupt the integrity of bacterial cell walls and lead to bacterial cell death.

Fluoroquinolones are a class of antibiotics that are commonly used to treat a wide range of bacterial infections. They work by inhibiting the growth and reproduction of bacteria by interfering with their ability to replicate their DNA. Fluoroquinolones are often used to treat respiratory tract infections, urinary tract infections, skin infections, and sexually transmitted infections. Some examples of fluoroquinolones include ciprofloxacin, levofloxacin, and moxifloxacin. It is important to note that fluoroquinolones should only be used to treat bacterial infections and should not be used to treat viral infections such as the flu or a cold. Additionally, fluoroquinolones can have serious side effects and should only be prescribed by a healthcare professional.

Bacteria are single-celled microorganisms that are found in almost every environment on Earth, including soil, water, and the human body. In the medical field, bacteria are often studied and classified based on their characteristics, such as their shape, size, and genetic makeup. Bacteria can be either beneficial or harmful to humans. Some bacteria are essential for human health, such as the bacteria that live in the gut and help digest food. However, other bacteria can cause infections and diseases, such as strep throat, pneumonia, and meningitis. In the medical field, bacteria are often identified and treated using a variety of methods, including culturing and identifying bacteria using specialized laboratory techniques, administering antibiotics to kill harmful bacteria, and using vaccines to prevent bacterial infections.

Bacteriolysis is the process by which bacteria are destroyed or lysed, typically by the action of enzymes produced by other bacteria or by the host immune system. This process is an important mechanism for controlling bacterial infections in the body. Bacteriolysis can occur through a variety of mechanisms, including the production of enzymes that degrade the bacterial cell wall, the production of toxins that damage the bacterial cell membrane, or the activation of the host immune system to attack and destroy the bacteria. Bacteriolysis can be induced by a variety of factors, including antibiotics, antiseptics, and other antimicrobial agents. It can also be induced by the host immune system in response to an infection. In the medical field, bacteriolysis is an important tool for treating bacterial infections. Antibiotics and other antimicrobial agents can be used to induce bacteriolysis and help eliminate the bacteria from the body. In some cases, bacteriolysis may also be induced by the host immune system as part of the body's natural defense against infection.

Pneumococcal vaccines are vaccines that are designed to protect against infections caused by Streptococcus pneumoniae, also known as pneumococcus. Pneumococcus is a common cause of pneumonia, meningitis, and other serious infections, particularly in young children, older adults, and people with certain medical conditions. There are currently two types of pneumococcal vaccines available: pneumococcal conjugate vaccine (PCV) and pneumococcal polysaccharide vaccine (PPSV). PCV is recommended for infants and young children, while PPSV is recommended for older adults and people with certain medical conditions. Pneumococcal vaccines work by stimulating the immune system to produce antibodies that can recognize and fight off pneumococcal bacteria. This can help prevent the bacteria from causing infections, or can help the body respond more effectively if it does become infected. It is important to note that while pneumococcal vaccines are highly effective at preventing serious infections, they are not 100% effective. Additionally, some strains of pneumococcus may not be covered by the vaccines, so it is still possible to get infected even if you have been vaccinated.

Teichoic acids are acidic polysaccharides that are found in the cell walls of certain bacteria, including Gram-positive bacteria. They are covalently linked to the peptidoglycan layer of the cell wall and play a role in maintaining the integrity and structure of the cell wall. Teichoic acids can also serve as a source of nutrients for bacteria and can play a role in bacterial adhesion and colonization of host tissues. In the medical field, teichoic acids are of interest because they are potential targets for the development of new antibiotics and other antimicrobial agents.

In the medical field, "Colony Count, Microbial" refers to the process of counting the number of colonies of microorganisms that have grown on a culture plate. This is a common laboratory technique used to determine the concentration or density of microorganisms in a sample. To perform a colony count, a sample is typically taken from a patient or an environmental source and then cultured on a nutrient-rich agar plate. The plate is incubated for a specific period of time to allow the microorganisms to grow and form colonies. The colonies are then counted and the results are expressed in colony-forming units (CFUs) per milliliter or per gram of the original sample. The colony count can be used to diagnose infections caused by microorganisms, to monitor the effectiveness of antimicrobial treatments, and to assess the quality of food and water. It is an important tool in the field of microbiology and is used in a variety of settings, including hospitals, laboratories, and research facilities.

In the medical field, a carrier state refers to a person who carries a specific infectious agent or genetic abnormality without showing any signs or symptoms of the disease or condition caused by it. For example, a person who carries the human immunodeficiency virus (HIV) but does not have symptoms of acquired immune deficiency syndrome (AIDS) is considered an HIV carrier. Similarly, a person who carries a gene mutation that increases their risk of developing a certain genetic disorder, such as cystic fibrosis, but does not show any symptoms of the disorder is also considered a carrier. Carriers can still transmit the infectious agent or genetic abnormality to others, even if they themselves are not affected by the disease or condition. This is why it is important to identify and manage carrier states in order to prevent the spread of infectious diseases and genetic disorders.

In the medical field, the cell wall is a rigid layer that surrounds the cell membrane of certain types of cells, such as plant cells and some bacteria. The cell wall provides structural support and protection to the cell, and helps to maintain its shape and integrity. It is composed of various polysaccharides, proteins, and other molecules, and is essential for the survival and function of these types of cells. In some cases, the cell wall may also play a role in cell division and communication with other cells.

In the medical field, carrier proteins are proteins that transport molecules across cell membranes or within cells. These proteins bind to specific molecules, such as hormones, nutrients, or waste products, and facilitate their movement across the membrane or within the cell. Carrier proteins play a crucial role in maintaining the proper balance of molecules within cells and between cells. They are involved in a wide range of physiological processes, including nutrient absorption, hormone regulation, and waste elimination. There are several types of carrier proteins, including facilitated diffusion carriers, active transport carriers, and ion channels. Each type of carrier protein has a specific function and mechanism of action. Understanding the role of carrier proteins in the body is important for diagnosing and treating various medical conditions, such as genetic disorders, metabolic disorders, and neurological disorders.

In the medical field, glucans refer to a group of polysaccharides that are composed of glucose molecules linked together by glycosidic bonds. Glucans are found in various organisms, including plants, fungi, and bacteria, and they play important roles in their biology and physiology. In humans, glucans have been studied for their potential health benefits, particularly in the context of immune function. Some types of glucans, such as beta-glucans, have been shown to stimulate the immune system and enhance the body's ability to fight off infections and diseases. Glucans have also been used in the development of dietary supplements and functional foods, as well as in the treatment of certain medical conditions, such as cancer and HIV/AIDS. Overall, glucans are an important class of biomolecules that have a wide range of biological and medical applications.

In the medical field, an amino acid sequence refers to the linear order of amino acids in a protein molecule. Proteins are made up of chains of amino acids, and the specific sequence of these amino acids determines the protein's structure and function. The amino acid sequence is determined by the genetic code, which is a set of rules that specifies how the sequence of nucleotides in DNA is translated into the sequence of amino acids in a protein. Each amino acid is represented by a three-letter code, and the sequence of these codes is the amino acid sequence of the protein. The amino acid sequence is important because it determines the protein's three-dimensional structure, which in turn determines its function. Small changes in the amino acid sequence can have significant effects on the protein's structure and function, and this can lead to diseases or disorders. For example, mutations in the amino acid sequence of a protein involved in blood clotting can lead to bleeding disorders.

Bacitracin is an antibiotic medication that is used to treat a variety of bacterial infections, including skin infections, urinary tract infections, and respiratory infections. It is typically used in combination with other antibiotics to increase its effectiveness. Bacitracin is derived from the bacterium Streptomyces subtilis and works by inhibiting the growth of bacteria by interfering with their ability to make cell walls. It is available in various forms, including ointments, creams, and solutions, and is usually applied topically to the affected area.

Bacterial outer membrane proteins (OMPs) are proteins that are located on the outer surface of the cell membrane of bacteria. They play important roles in the survival and pathogenicity of bacteria, as well as in their interactions with the environment and host cells. OMPs can be classified into several categories based on their function, including porins, which allow the passage of small molecules and ions across the outer membrane, and lipoproteins, which are anchored to the outer membrane by a lipid moiety. Other types of OMPs include adhesins, which mediate the attachment of bacteria to host cells or surfaces, and toxins, which can cause damage to host cells. OMPs are important targets for the development of new antibiotics and other antimicrobial agents, as they are often essential for bacterial survival and can be differentially expressed by different bacterial strains or species. They are also the subject of ongoing research in the fields of microbiology, immunology, and infectious diseases.

In the medical field, a base sequence refers to the specific order of nucleotides (adenine, thymine, cytosine, and guanine) that make up the genetic material (DNA or RNA) of an organism. The base sequence determines the genetic information encoded within the DNA molecule and ultimately determines the traits and characteristics of an individual. The base sequence can be analyzed using various techniques, such as DNA sequencing, to identify genetic variations or mutations that may be associated with certain diseases or conditions.

Esculin is a type of sugar that is found in the cell walls of plants, particularly in the bark of certain trees such as oak and beech. It is a complex carbohydrate that is composed of glucose molecules linked together in a specific arrangement. In the medical field, esculin is used as a diagnostic tool to test for the presence of certain enzymes in the body. Specifically, it is used to test for the activity of alpha-glucosidase, an enzyme that is involved in the breakdown of complex carbohydrates. When alpha-glucosidase breaks down esculin, it produces a colored compound that can be detected and measured. Esculin tests are commonly used in clinical laboratories to diagnose and monitor a variety of conditions, including diabetes, celiac disease, and certain types of liver and pancreatic disorders. They are also used in research to study the function of alpha-glucosidase and other enzymes involved in carbohydrate metabolism.

Aminoacyltransferases are a group of enzymes that play a crucial role in protein synthesis. They catalyze the transfer of an amino acid from a donor molecule, such as a tRNA molecule, to an acceptor molecule, such as a ribosome-bound mRNA molecule. This process is known as aminoacylation and is a key step in the translation of genetic information into proteins. There are two main types of aminoacyltransferases: aminoacyl-tRNA synthetases and aminoacyl-tRNA ligases. Aminoacyl-tRNA synthetases are responsible for attaching the correct amino acid to its corresponding tRNA molecule, while aminoacyl-tRNA ligases are responsible for attaching the aminoacyl-tRNA molecule to the ribosome. Aminoacyltransferases are essential for the proper functioning of the cell and are involved in a wide range of biological processes, including protein synthesis, metabolism, and signal transduction. Mutations in aminoacyltransferase genes can lead to a variety of diseases, including genetic disorders such as cystic fibrosis and muscular dystrophy.

Clindamycin is an antibiotic medication that is used to treat a variety of bacterial infections. It is a lincosamide antibiotic that works by stopping the growth of bacteria. Clindamycin is often used to treat infections of the skin, respiratory tract, and reproductive system, as well as certain types of bacterial infections that are resistant to other antibiotics. It is usually taken by mouth or given by injection, depending on the type and severity of the infection being treated. Clindamycin can cause side effects such as nausea, diarrhea, and stomach pain, and it may interact with other medications, so it is important to follow your healthcare provider's instructions carefully when taking this medication.

Ketolides are a class of antibiotics that are similar in structure to macrolides, but with a ketolide ring instead of a macrolide ring. They are used to treat bacterial infections such as community-acquired pneumonia, acute bacterial sinusitis, and skin and skin structure infections caused by certain types of bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, and Moraxella catarrhalis. Ketolides work by inhibiting bacterial protein synthesis, which is necessary for the bacteria to grow and reproduce. They are generally well-tolerated and have a good safety profile, but like other antibiotics, they can cause side effects such as nausea, diarrhea, and abdominal pain.

Bacteremia is a medical condition in which bacteria are present in the bloodstream. It is a serious condition that can lead to sepsis, a life-threatening condition that occurs when the body's response to an infection causes widespread inflammation and organ damage. Bacteremia can be caused by a variety of bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, and Escherichia coli. It can be diagnosed through blood cultures, which involve taking a sample of blood and growing the bacteria in a laboratory to confirm the presence of the bacteria. Treatment for bacteremia typically involves antibiotics to kill the bacteria and manage the symptoms of the infection.

In the medical field, blood refers to the liquid component of the circulatory system that carries oxygen, nutrients, hormones, and waste products throughout the body. It is composed of red blood cells, white blood cells, platelets, and plasma. Red blood cells, also known as erythrocytes, are responsible for carrying oxygen from the lungs to the body's tissues and carbon dioxide from the tissues to the lungs. White blood cells, also known as leukocytes, are part of the immune system and help protect the body against infections and diseases. Platelets, also known as thrombocytes, are involved in blood clotting and help prevent excessive bleeding. Plasma is the liquid portion of blood that contains water, proteins, electrolytes, and other substances. Blood is collected through a process called phlebotomy, which involves drawing blood from a vein using a needle. Blood can be used for a variety of medical tests and procedures, including blood typing, blood transfusions, and the diagnosis of various medical conditions.

Opsonin proteins are a type of immune system protein that play a role in the process of phagocytosis, which is the process by which immune cells called phagocytes engulf and destroy foreign particles, such as bacteria or viruses. Opsonins bind to the surface of these foreign particles, marking them for destruction by phagocytes. This process is known as opsonization. There are several different types of opsonin proteins, including antibodies, complement proteins, and mannose-binding lectin (MBL). Antibodies are proteins produced by the immune system in response to the presence of a foreign substance, such as a virus or bacteria. They bind to specific molecules on the surface of these foreign particles, marking them for destruction by phagocytes. Complement proteins are a group of proteins that are part of the innate immune system. They are produced by the liver and other organs and circulate in the blood. Complement proteins can bind to foreign particles and mark them for destruction by phagocytes. MBL is a protein that is produced by the liver and circulates in the blood. It binds to specific molecules on the surface of foreign particles, marking them for destruction by phagocytes. Opsonin proteins play an important role in the immune system by helping to identify and destroy foreign particles. They are an important part of the body's defense against infection and disease.

Lactose is a disaccharide sugar found in milk and other dairy products. It is composed of two molecules of glucose and one molecule of galactose, which are linked together by a glycosidic bond. In the medical field, lactose intolerance is a common condition in which the body is unable to digest lactose properly. This can lead to symptoms such as bloating, gas, diarrhea, and abdominal pain. Lactose intolerance is often caused by a deficiency in the enzyme lactase, which is responsible for breaking down lactose in the small intestine. In some cases, lactose intolerance may be treated with lactase supplements or by avoiding foods that contain lactose. However, for individuals with severe lactose intolerance, it may be necessary to follow a lactose-free diet.

Otitis Media is a medical condition that refers to the inflammation or infection of the middle ear. It is commonly known as "ear infection" and is one of the most common childhood illnesses. The middle ear is the space behind the eardrum that contains three small bones called ossicles, which help to transmit sound vibrations from the eardrum to the inner ear. When the middle ear becomes inflamed or infected, it can cause pain, fever, and other symptoms. Otitis Media can be caused by a variety of factors, including bacteria, viruses, and allergies. It is typically treated with antibiotics, pain relievers, and other medications, and in some cases, surgery may be necessary.

Sucrose is a disaccharide sugar that is commonly found in many foods and beverages, including fruits, vegetables, and sweetened beverages. In the medical field, sucrose is often used as a source of energy for patients who are unable to consume other sources of calories, such as solid foods. It is also used as a diagnostic tool in medical testing, such as in the measurement of blood glucose levels in people with diabetes. In some cases, sucrose may be used as a medication to treat certain medical conditions, such as low blood sugar levels. However, it is important to note that excessive consumption of sucrose can lead to weight gain and other health problems, so it should be consumed in moderation as part of a balanced diet.

Hexosyltransferases are a group of enzymes that transfer a hexose sugar moiety from a donor molecule to an acceptor molecule. These enzymes play a crucial role in the biosynthesis of various complex carbohydrates, such as glycans, glycoproteins, and glycolipids, which are essential components of cell membranes and extracellular matrix. In the medical field, hexosyltransferases are involved in various diseases and disorders, including cancer, diabetes, and autoimmune diseases. For example, mutations in certain hexosyltransferase genes can lead to the development of inherited disorders such as glycogen storage diseases, which are characterized by the accumulation of abnormal glycogen in various tissues. In addition, hexosyltransferases are also important targets for the development of new drugs and therapies. For instance, inhibitors of hexosyltransferases have been shown to have anti-cancer properties by disrupting the biosynthesis of glycoproteins and glycolipids that are involved in tumor growth and metastasis.

Tonsillitis is an inflammation of the tonsils, which are two masses of tissue located at the back of the throat. The inflammation can be caused by a viral or bacterial infection, and it is characterized by swelling, redness, and pain in the tonsils. Other symptoms of tonsillitis may include fever, difficulty swallowing, a sore throat, and a white or yellow coating on the tonsils. Tonsillitis is a common condition, particularly in children, and it is usually treated with antibiotics if it is caused by bacteria. In some cases, the tonsils may need to be removed surgically if they become repeatedly infected or cause other problems.

Penicillin-Binding Proteins (PBPs) are enzymes found in the cell walls of bacteria that are responsible for cross-linking peptidoglycan strands, which is a key component of bacterial cell walls. PBPs are targeted by many antibiotics, including penicillins, cephalosporins, and carbapenems, which inhibit their activity and prevent the formation of a stable cell wall, leading to bacterial cell lysis and death. PBPs are classified into several classes based on their molecular weight and substrate specificity. Class A PBPs are the most common and are found in most bacteria, including Gram-positive and Gram-negative bacteria. Class B PBPs are found only in Gram-positive bacteria, while class C PBPs are found only in Gram-negative bacteria. Class D PBPs are found in both Gram-positive and Gram-negative bacteria and are responsible for resistance to beta-lactam antibiotics. In summary, PBPs are essential enzymes for bacterial cell wall synthesis and are targeted by many antibiotics, making them important targets for the development of new antibiotics to combat bacterial infections.

Ceftriaxone is an antibiotic medication that is used to treat a variety of bacterial infections. It is a cephalosporin antibiotic, which means that it works by stopping the growth of bacteria. Ceftriaxone is often used to treat infections of the respiratory tract, urinary tract, and skin, as well as infections that affect the bones and joints, blood, and central nervous system. It is usually given by injection, although it is also available in an oral form. Ceftriaxone is a powerful antibiotic and can be effective against many types of bacteria, but it is important to use it only as directed by a healthcare provider to avoid the development of antibiotic resistance.

Rheumatic fever is a systemic inflammatory disease that occurs as a result of a streptococcal infection, typically of the throat or skin. It is most commonly seen in children between the ages of 5 and 15, but can also occur in adults. The disease is characterized by a variety of symptoms, including fever, joint pain and swelling, aching muscles, and a rash. In some cases, it can also cause inflammation of the heart, brain, and other organs. Rheumatic fever is caused by the body's immune response to the streptococcal infection. The immune system produces antibodies that attack the bacteria, but in some cases, these antibodies can also attack healthy tissue in the body, leading to inflammation and damage. Rheumatic fever is typically treated with antibiotics to eliminate the streptococcal infection and prevent further inflammation. In some cases, medications may also be used to reduce inflammation and prevent damage to the heart and other organs.

Cefotaxime is an antibiotic medication that is used to treat a variety of bacterial infections, including pneumonia, meningitis, urinary tract infections, and gonorrhea. It is a cephalosporin antibiotic, which means that it works by stopping the growth of bacteria. Cefotaxime is typically administered intravenously, although it may also be available as an oral medication. It is important to note that cefotaxime is only effective against bacterial infections and will not work against viral infections. It is also important to follow the dosing instructions provided by your healthcare provider and to complete the full course of treatment, even if you start to feel better before the medication is finished.

Rhamnose is a type of sugar molecule that is found in many different types of plants and microorganisms. It is a pentose sugar, meaning that it has five carbon atoms in its ring structure. In the medical field, rhamnose is sometimes used as a dietary supplement or as an ingredient in certain medications. It has been studied for its potential health benefits, including its ability to improve digestion, boost the immune system, and reduce inflammation. However, more research is needed to fully understand the potential benefits and risks of rhamnose supplementation.

DNA Topoisomerase IV is an enzyme that plays a crucial role in DNA replication and repair. It is a type of topoisomerase that is responsible for relaxing the supercoiled DNA molecules that are formed during DNA replication and transcription. This enzyme works by cutting one or both strands of DNA, allowing them to rotate and then rejoin, resulting in the relaxation of the supercoiled DNA. DNA Topoisomerase IV is also involved in the resolution of DNA double-strand breaks, which can occur as a result of various cellular processes, including DNA replication, transcription, and exposure to DNA-damaging agents such as ionizing radiation and certain chemotherapy drugs. By relaxing the supercoiled DNA around the double-strand break, DNA Topoisomerase IV helps to facilitate the repair of the break. In the medical field, DNA Topoisomerase IV is an important target for the development of anti-cancer drugs. Many of the most widely used anti-cancer drugs, such as the anthracyclines and the quinolones, work by inhibiting the activity of DNA Topoisomerase IV, leading to the accumulation of DNA damage and ultimately the death of cancer cells. However, these drugs can also cause significant side effects, including bone marrow suppression and cardiac toxicity, which can limit their use in certain patients.

RNA, Ribosomal, 16S is a type of ribosomal RNA (rRNA) that is found in bacteria and archaea. It is a small subunit of the ribosome, which is the cellular machinery responsible for protein synthesis. The 16S rRNA is located in the 30S subunit of the ribosome and is essential for the binding and decoding of messenger RNA (mRNA) during translation. The sequence of the 16S rRNA is highly conserved among bacteria and archaea, making it a useful target for the identification and classification of these organisms. In the medical field, the 16S rRNA is often used in molecular biology techniques such as polymerase chain reaction (PCR) and DNA sequencing to study the diversity and evolution of bacterial and archaeal populations. It is also used in the development of diagnostic tests for bacterial infections and in the identification of antibiotic-resistant strains of bacteria.

Fasciitis, Necrotizing is a rare and serious medical condition characterized by the inflammation and necrosis (death) of the fascia, which is the connective tissue that surrounds and supports muscles, tendons, and other structures in the body. The condition is also known as fasciitis with necrotizing fasciitis, or NF, and is caused by a group of bacteria that can enter the body through a cut or wound, or through the bloodstream. The bacteria release toxins that damage the fascia and cause it to become inflamed and necrotic. Symptoms of necrotizing fasciitis include severe pain, redness, swelling, and fever. In severe cases, the infection can spread rapidly and cause organ failure, sepsis, and even death if not treated promptly. Treatment for necrotizing fasciitis typically involves antibiotics to fight the infection, as well as surgery to remove the damaged tissue and prevent the spread of the infection. In some cases, supportive care such as intravenous fluids and oxygen therapy may also be necessary.

RNA, Bacterial refers to the ribonucleic acid molecules that are produced by bacteria. These molecules play a crucial role in the functioning of bacterial cells, including the synthesis of proteins, the regulation of gene expression, and the metabolism of nutrients. Bacterial RNA can be classified into several types, including messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), which all have specific functions within the bacterial cell. Understanding the structure and function of bacterial RNA is important for the development of new antibiotics and other treatments for bacterial infections.

Mastitis, bovine refers to an inflammation of the mammary gland in cows. It is a common and costly disease in the dairy industry, affecting both dairy cows and beef cattle. The inflammation can be caused by a variety of factors, including bacterial infections, viral infections, and physical injury to the mammary gland. Symptoms of bovine mastitis include swelling and redness of the mammary gland, decreased milk production, and fever in the cow. Treatment typically involves antibiotics to treat bacterial infections and supportive care to manage the symptoms of the disease. Prevention measures include good hygiene practices during milking, proper nutrition and management of the cows, and regular monitoring of the health of the herd.

Tetracycline is a broad-spectrum antibiotic that is commonly used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, and sexually transmitted infections. It works by inhibiting the growth of bacteria by blocking the synthesis of proteins that are essential for bacterial growth and reproduction. Tetracycline is available in various forms, including tablets, capsules, and liquid solutions. It is usually taken orally, although it can also be given intravenously in severe cases. Tetracycline is generally well-tolerated, but it can cause side effects such as nausea, vomiting, diarrhea, and stomach pain. It can also cause tooth discoloration and interfere with the development of bones in children. Tetracycline is not recommended for use in pregnant women or children under the age of eight, as it can cause permanent discoloration of the teeth and interfere with bone development. It is also not recommended for use in people with certain medical conditions, such as liver or kidney disease, or in those who are allergic to tetracycline or other antibiotics.

Bacterial vaccines are vaccines that are designed to protect against bacterial infections. They work by stimulating the immune system to recognize and fight off specific bacteria that cause disease. Bacterial vaccines can be made from live, attenuated bacteria (bacteria that have been weakened so they cannot cause disease), inactivated bacteria (bacteria that have been killed), or pieces of bacteria (such as proteins or polysaccharides) that are recognized by the immune system. Bacterial vaccines are used to prevent a wide range of bacterial infections, including diphtheria, tetanus, pertussis, typhoid fever, and meningococcal disease. They are typically given by injection, but some can also be given by mouth. Bacterial vaccines are an important tool in preventing the spread of bacterial infections and reducing the burden of disease in the population.

Agglutination tests are a type of diagnostic test used in the medical field to detect the presence of specific antigens or antibodies in a patient's blood or other bodily fluids. These tests work by causing the clumping or agglutination of red blood cells or other cells in the presence of specific antibodies or antigens. There are several types of agglutination tests, including direct agglutination tests, indirect agglutination tests, and counterimmunoelectrophoresis (CIE) tests. Direct agglutination tests involve mixing a patient's blood or other bodily fluids with a known antigen or antibody, and observing whether the cells clump together. Indirect agglutination tests involve using an intermediate substance, such as an antiserum, to bind the antigen or antibody to the cells, and then observing whether the cells clump together. CIE tests involve separating antibodies and antigens by charge and then observing whether they react with each other. Agglutination tests are commonly used to diagnose a variety of medical conditions, including infectious diseases, autoimmune disorders, and blood disorders. They are often used in conjunction with other diagnostic tests, such as serological tests and immunofluorescence assays, to provide a more complete picture of a patient's health.

Skin diseases caused by bacteria are a common type of infection that can affect people of all ages and genders. These infections can range from mild to severe and can affect different parts of the body, including the face, neck, arms, legs, and torso. Some common bacterial skin diseases include acne, impetigo, cellulitis, folliculitis, and erysipelas. Acne is a common skin condition that affects the hair follicles and sebaceous glands, causing pimples, blackheads, and whiteheads. Impetigo is a highly contagious skin infection that usually affects children and is caused by the bacteria Streptococcus pyogenes or Staphylococcus aureus. Cellulitis is a serious skin infection that can spread quickly and cause swelling, redness, and pain. Folliculitis is an infection of the hair follicles that can cause redness, swelling, and pus-filled bumps. Erysipelas is a severe skin infection that can cause redness, swelling, and fever. Treatment for bacterial skin diseases typically involves the use of antibiotics, either topically or orally, depending on the severity of the infection. In some cases, hospitalization may be necessary for severe infections. It is important to seek medical attention if you suspect you have a bacterial skin infection, as untreated infections can lead to complications and spread to other parts of the body.

Cephalosporins are a class of antibiotics that are derived from the mold species Cephalosporium acremonium. They are commonly used to treat a wide range of bacterial infections, including respiratory tract infections, skin infections, urinary tract infections, and infections of the bones and joints. Cephalosporins work by inhibiting the synthesis of bacterial cell walls, which leads to the death of the bacteria. They are generally well-tolerated and have a broad spectrum of activity against many types of bacteria. There are several different classes of cephalosporins, each with its own specific characteristics and uses. The most commonly used classes are first-generation cephalosporins, second-generation cephalosporins, third-generation cephalosporins, and fourth-generation cephalosporins. The choice of which cephalosporin to use depends on the type of infection being treated, the severity of the infection, and the specific characteristics of the bacteria causing the infection.

In the medical field, "antibiosis" refers to the phenomenon where one microorganism inhibits the growth or reproduction of another microorganism. This can occur naturally between different species of bacteria, fungi, or other microorganisms, or it can be artificially induced through the use of antibiotics. Antibiosis is an important concept in the field of medicine, as it has led to the development of antibiotics, which are drugs that can kill or inhibit the growth of bacteria. Antibiotics are used to treat a wide range of bacterial infections, including pneumonia, strep throat, and urinary tract infections. However, it is important to note that not all microorganisms exhibit antibiosis, and some may even be mutualistic, meaning they benefit from each other's presence. Additionally, the overuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which can be difficult to treat and pose a significant public health threat.

Agglutinins are a type of antibody that binds to specific antigens on the surface of cells or pathogens, causing them to clump together or agglutinate. They are a type of immunoglobulin, which are proteins produced by the immune system in response to the presence of foreign substances, such as bacteria, viruses, or other pathogens. There are several types of agglutinins, including: 1. Antibody agglutinins: These are antibodies that bind to specific antigens on the surface of pathogens, causing them to clump together. Antibody agglutinins are produced by B cells in response to an infection or vaccination. 2. Lectins: These are proteins that bind to specific carbohydrate structures on the surface of cells or pathogens, causing them to agglutinate. Lectins are produced by a variety of organisms, including plants, animals, and microorganisms. 3. Complement system proteins: These are proteins that are part of the complement system, a series of proteins that work together to destroy pathogens. Some complement system proteins, such as C3b and C4b, can also act as agglutinins. Agglutination can be a useful diagnostic tool in medicine, as it can help identify specific pathogens or other foreign substances in a sample. For example, agglutination tests are commonly used to diagnose infections caused by bacteria such as Streptococcus pneumoniae and Haemophilus influenzae, as well as to detect the presence of certain viruses such as influenza and rubella.

Levofloxacin is an antibiotic medication that is used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, and bone and joint infections. It is a fluoroquinolone antibiotic, which means that it works by inhibiting the growth of bacteria by interfering with their ability to replicate. Levofloxacin is available in oral and intravenous forms and is generally well-tolerated by most people. However, like all antibiotics, it can cause side effects, such as nausea, diarrhea, and headache. It is important to take levofloxacin exactly as prescribed by a healthcare provider and to complete the full course of treatment, even if symptoms improve before the medication is finished.

In the medical field, adhesiveness refers to the ability of tissues or organs to stick together or to other surfaces. This can be an important factor in various medical conditions and treatments. For example, adhesiveness can play a role in the development of adhesions, which are bands of scar tissue that form between organs or tissues after surgery or injury. Adhesions can cause pain, bowel obstruction, and other complications. Adhesiveness can also be important in wound healing, where the ability of cells to stick together and form a cohesive tissue is crucial for proper healing. In some cases, medications or other treatments may be used to reduce adhesiveness in order to prevent the formation of adhesions or to help break down existing adhesions.

Respiratory tract infections (RTIs) are a group of infections that affect the respiratory system, which includes the nose, throat, sinuses, larynx, trachea, bronchi, and lungs. RTIs can be caused by a variety of viruses, bacteria, fungi, and other microorganisms. Common symptoms of RTIs include coughing, sore throat, runny or stuffy nose, fever, and difficulty breathing. RTIs can range from mild to severe and can affect people of all ages, although young children, older adults, and people with weakened immune systems are more susceptible to severe infections. Treatment for RTIs depends on the specific cause and severity of the infection, and may include medications, rest, and fluids. In some cases, hospitalization may be necessary.

Hydroxyapatite is a mineral that is commonly found in bone and tooth enamel. In the medical field, hydroxyapatite is often used as a biomaterial for various medical applications, such as bone grafting, dental implants, and drug delivery systems. It is also used in the production of medical devices, such as orthopedic implants and prosthetic devices. Hydroxyapatite has excellent biocompatibility and can be easily modified to enhance its properties for specific medical applications.

Ofloxacin is an antibiotic medication that belongs to the class of fluoroquinolones. It is used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, and sexually transmitted infections. Ofloxacin works by inhibiting the growth of bacteria by interfering with their ability to replicate. It is available in oral and injectable forms and is generally well-tolerated, although it can cause side effects such as nausea, diarrhea, and headache. Ofloxacin is not effective against viral infections and should not be used to treat such conditions.

Meningitis is an inflammation of the protective membranes (meninges) that surround the brain and spinal cord. It can be caused by various factors, including bacterial, viral, fungal, or parasitic infections, as well as certain autoimmune diseases or reactions to medications. The symptoms of meningitis can vary depending on the cause and severity of the inflammation, but common signs include fever, headache, neck stiffness, sensitivity to light, and a rash. In severe cases, meningitis can lead to complications such as brain damage, hearing loss, seizures, and even death. Prompt diagnosis and treatment of meningitis are crucial to prevent serious complications and improve outcomes. Treatment typically involves antibiotics or antiviral medications, as well as supportive care to manage symptoms and prevent dehydration.

In the medical field, agar is a gelatinous substance that is commonly used as a growth medium for bacteria, fungi, and other microorganisms. It is made from seaweed and is composed of agarose, a polysaccharide that forms a gel when heated. Agar is often used in microbiology laboratories to culture and isolate microorganisms, as well as to study their growth and behavior. It is also used in some medical treatments, such as in the preparation of certain types of vaccines and in the treatment of certain skin conditions.

Naphthyridines are a class of organic compounds that contain a naphthalene ring fused to a pyridine ring. They are commonly used in the medical field as drugs and as intermediates in the synthesis of other drugs. Some examples of drugs that contain naphthyridine moieties include the antihistamine cetrizine, the antipsychotic drug risperidone, and the antiviral drug tenofovir. Naphthyridines have a variety of pharmacological properties, including antihistaminic, antipsychotic, antiviral, and anti-inflammatory effects. They are also used as dyes and as intermediates in the synthesis of other organic compounds.

In the medical field, cross reactions refer to the phenomenon where an individual's immune system reacts to a substance that it has not been specifically exposed to before, but has a similar molecular structure to a substance that it has previously encountered. This can occur when an individual has been exposed to a substance that triggers an immune response, and then later encounters a similar substance that triggers a similar response. For example, if an individual is allergic to peanuts, their immune system may produce antibodies that react to the proteins in peanuts. If they later encounter a similar protein in a different food, such as tree nuts, their immune system may also produce antibodies that react to the protein in tree nuts, even though they have never been exposed to tree nuts before. This is known as a cross reaction. Cross reactions can occur in a variety of medical contexts, including allergies, autoimmune diseases, and infections. They can also occur with vaccines, where the vaccine contains a small amount of a similar substance to the pathogen that it is designed to protect against. In some cases, cross reactions can be mild and harmless, while in other cases they can be severe and even life-threatening.

Hemolysis is the breakdown of red blood cells (RBCs) in the bloodstream. This process can occur due to various factors, including mechanical stress, exposure to certain medications or toxins, infections, or inherited genetic disorders. When RBCs are damaged or destroyed, their contents, including hemoglobin, are released into the bloodstream. Hemoglobin is a protein that carries oxygen from the lungs to the body's tissues and carbon dioxide from the tissues back to the lungs. When hemoglobin is released into the bloodstream, it can cause the blood to appear dark brown or black, a condition known as hemoglobinuria. Hemolysis can lead to a variety of symptoms, including jaundice (yellowing of the skin and eyes), fatigue, shortness of breath, abdominal pain, and dark urine. In severe cases, hemolysis can cause life-threatening complications, such as kidney failure or shock. Treatment for hemolysis depends on the underlying cause. In some cases, treatment may involve medications to slow down the breakdown of RBCs or to remove excess hemoglobin from the bloodstream. In other cases, treatment may involve blood transfusions or other supportive therapies to manage symptoms and prevent complications.

Cloning, molecular, in the medical field refers to the process of creating identical copies of a specific DNA sequence or gene. This is achieved through a technique called polymerase chain reaction (PCR), which amplifies a specific DNA sequence to produce multiple copies of it. Molecular cloning is commonly used in medical research to study the function of specific genes, to create genetically modified organisms for therapeutic purposes, and to develop new drugs and treatments. It is also used in forensic science to identify individuals based on their DNA. In the context of human cloning, molecular cloning is used to create identical copies of a specific gene or DNA sequence from one individual and insert it into the genome of another individual. This technique has been used to create transgenic animals, but human cloning is currently illegal in many countries due to ethical concerns.

Immune sera refers to a type of blood serum that contains antibodies produced by the immune system in response to an infection or vaccination. These antibodies are produced by B cells, which are a type of white blood cell that plays a key role in the immune response. Immune sera can be used to diagnose and treat certain infections, as well as to prevent future infections. For example, immune sera containing antibodies against a specific virus or bacteria can be used to diagnose a current infection or to prevent future infections in people who have been exposed to the virus or bacteria. Immune sera can also be used as a research tool to study the immune response to infections and to develop new vaccines and treatments. In some cases, immune sera may be used to treat patients with severe infections or allergies, although this is less common than using immune sera for diagnostic or preventive purposes.

Bacterial infections are caused by bacteria, which are single-celled microorganisms that can be found almost everywhere in the environment, including on our skin and in our digestive tracts. When bacteria enter the body and multiply, they can cause illness and disease. Bacterial infections can affect any part of the body and can range from mild to severe. Some common examples of bacterial infections include strep throat, urinary tract infections, pneumonia, meningitis, and skin infections. Bacterial infections can be treated with antibiotics, which are medications that kill or inhibit the growth of bacteria. However, it is important to use antibiotics properly and only when necessary, as overuse can lead to antibiotic resistance, which makes it more difficult to treat bacterial infections in the future.

In the medical field, agglutination refers to the clumping or aggregation of red blood cells or other cells in a liquid suspension. This can occur due to the presence of antibodies or other substances that bind to specific antigens on the surface of the cells, causing them to clump together. Agglutination is often used as a diagnostic tool in medical testing, as it can help identify the presence of certain diseases or conditions. For example, agglutination tests are commonly used to diagnose infectious diseases such as syphilis, hepatitis, and meningitis, as well as to screen for blood transfusion reactions. Agglutination can also occur in the immune system as a normal response to infection or injury. In this case, antibodies produced by the immune system bind to antigens on the surface of invading pathogens or damaged cells, causing them to clump together and be more easily eliminated by the immune system.

Impetigo is a highly contagious skin infection caused by bacteria, most commonly Staphylococcus aureus or Streptococcus pyogenes. It is most common in children, but can affect people of all ages. The infection typically appears as red, itchy, and painful sores or blisters on the skin, which may crust over and eventually rupture. Impetigo can spread through direct contact with infected skin, or through contaminated objects or surfaces. It is usually treated with antibiotics, and it is important to follow good hygiene practices to prevent the spread of the infection.

Sepsis is a serious medical condition that occurs when the body's response to an infection causes widespread inflammation throughout the body. It is a life-threatening condition that can lead to organ failure, septic shock, and even death if not treated promptly and effectively. Sepsis can develop from any type of infection, including bacterial, viral, fungal, or parasitic infections. The body's immune system responds to the infection by releasing chemicals called cytokines, which can cause inflammation throughout the body. This inflammation can damage tissues and organs, leading to a range of symptoms, including fever, chills, rapid heartbeat, rapid breathing, confusion, and decreased urine output. Diagnosis of sepsis typically involves a combination of clinical examination, laboratory tests, and imaging studies. Treatment typically involves antibiotics to treat the underlying infection, as well as supportive care to manage symptoms and prevent complications. In severe cases, treatment may include fluid resuscitation, vasopressors to maintain blood pressure, and organ support. Early recognition and prompt treatment of sepsis are critical for improving outcomes and reducing the risk of death.

Vaccines, conjugate are a type of vaccine that uses a carrier protein to enhance the immune response to a specific bacterial or viral pathogen. The carrier protein is usually a protein that is found in the body, such as diphtheria toxin or tetanus toxin, and is conjugated to a small piece of the pathogen, such as a polysaccharide or protein. This conjugation helps the immune system recognize and respond to the pathogen more effectively, particularly in young children whose immune systems may not be as developed as those of adults. Conjugate vaccines are used to prevent a variety of bacterial and viral diseases, including pertussis, Haemophilus influenzae type b, and pneumococcal disease.

DNA gyrase is an enzyme that plays a crucial role in DNA replication and repair in bacteria. It is responsible for unwinding and relaxing the supercoiled DNA double helix, which is necessary for the separation of the two strands during replication and the access of repair enzymes to damaged DNA. DNA gyrase is a type of topoisomerase, which is a family of enzymes that modify the topology of DNA by introducing or removing supercoils. In bacteria, DNA gyrase is composed of two subunits, A and B, and it requires ATP to function. In the medical field, DNA gyrase is an important target for antibiotics, as many antibiotics work by inhibiting the activity of DNA gyrase. For example, quinolones, a class of antibiotics commonly used to treat bacterial infections, target DNA gyrase and prevent it from unwinding and relaxing DNA. However, the overuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which is a major public health concern.

Muramoylpentapeptide Carboxypeptidase (MCP) is an enzyme that plays a crucial role in the metabolism of bacterial cell walls. It is a zinc-dependent metalloprotease that cleaves the terminal alanine residue from the pentapeptide side chain of muramic acid, a component of peptidoglycan, the main structural component of bacterial cell walls. MCP is produced by a variety of bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis. It is involved in the regulation of cell wall biosynthesis and plays a role in bacterial pathogenesis. Inhibition of MCP activity has been shown to have potential therapeutic applications in the treatment of bacterial infections. In the medical field, MCP is often studied as a target for the development of new antibiotics and antimicrobial agents. Additionally, MCP has been shown to be involved in the pathogenesis of certain diseases, such as tuberculosis and pneumonia, and may be a potential target for the development of new treatments for these conditions.

Swine diseases refer to any illness or infection that affects pigs. These diseases can be caused by a variety of factors, including viruses, bacteria, parasites, fungi, and environmental factors. Swine diseases can range from mild to severe and can affect pigs of all ages and sizes. Some common swine diseases include: 1. Porcine Reproductive and Respiratory Syndrome (PRRS) 2. Swine Influenza (Swine Flu) 3. Porcine Circovirus Type 2 (PCV2) 4. Porcine Parvovirus (PPV) 5. Porcine Epidemic Diarrhea (PED) 6. Swine Leukosis Virus (SLV) 7. Porcine Dermatitis and Necrosis Syndrome (PDNS) 8. Porcine Enterotoxemia (PED) 9. Porcine Circovirus Type 1 (PCV1) 10. Porcine Circovirus Type 3 (PCV3) Swine diseases can have significant economic impacts on the pork industry, as well as on animal welfare and public health. Therefore, it is important for veterinarians, farmers, and other stakeholders to be aware of the signs and symptoms of swine diseases and to take appropriate measures to prevent and control their spread.

Scarlet fever is a bacterial infection caused by Group A Streptococcus (GAS) bacteria. It is characterized by a distinctive red rash that spreads over the body, accompanied by fever, sore throat, and swollen lymph nodes. The rash typically begins on the face and neck and spreads down the body, appearing as a fine, red, sandpaper-like texture. The fever can be high and may be accompanied by nausea, vomiting, and abdominal pain. In severe cases, complications such as kidney damage, rheumatic fever, and scarlet fever toxic shock syndrome can occur. Treatment typically involves antibiotics to clear the bacterial infection and supportive care to manage symptoms.

Peptidyl transferases are enzymes that catalyze the formation of peptide bonds between amino acids during protein synthesis. They are responsible for the elongation of polypeptide chains by transferring the growing polypeptide chain from the ribosome's A site to the P site, where it is joined to the next amino acid. Peptidyl transferases are essential for the proper functioning of ribosomes, which are the cellular machinery responsible for protein synthesis. There are two main types of peptidyl transferases: ribosomal peptidyl transferases, which are found in ribosomes, and non-ribosomal peptidyl transferases, which are found in various cellular compartments and are involved in the synthesis of non-proteinogenic peptides.

Lincomycin is an antibiotic medication that is used to treat a variety of bacterial infections. It is a member of the lincosamide class of antibiotics and works by inhibiting the growth of bacteria. Lincomycin is typically used to treat infections of the skin, respiratory tract, and urinary tract, as well as certain types of pneumonia and other respiratory infections. It is usually given intravenously or orally in the form of a liquid or tablet. Lincomycin may also be used to prevent infections in people who are at high risk, such as those who have had organ transplants or who are undergoing surgery. It is important to note that lincomycin is not effective against viral infections and should not be used to treat such infections.

The Phosphoenolpyruvate Sugar Phosphotransferase System (PTS) is a widespread metabolic pathway found in many bacteria, archaea, and some eukaryotes. It is responsible for the transport and phosphorylation of various sugars and other carbohydrates into the cell, and plays a crucial role in regulating carbohydrate metabolism and energy production. The PTS consists of a series of enzyme complexes that are capable of recognizing and binding to specific sugars and other carbohydrates on the cell surface. Once a sugar molecule is bound, it is phosphorylated by the enzyme complex, which transfers a phosphate group from a high-energy donor molecule (such as ATP) to the sugar. This phosphorylated sugar is then transported into the cell through a membrane-bound transporter protein. The PTS is a highly regulated system, with multiple levels of control that allow cells to adjust their carbohydrate metabolism in response to changes in environmental conditions. For example, when glucose levels are high, the PTS can switch off glucose transport and metabolism, while switching on the transport and metabolism of other sugars that are more abundant in the environment. This allows cells to efficiently utilize the available carbohydrates and conserve energy.

Peptide hydrolases are a class of enzymes that catalyze the hydrolysis of peptide bonds, which are the covalent bonds that link amino acids together to form peptides and proteins. These enzymes are involved in a wide range of biological processes, including digestion, immune response, and hormone regulation. There are several subclasses of peptide hydrolases, including proteases, peptidases, and endopeptidases. Proteases are enzymes that break down proteins into smaller peptides, while peptidases break down peptides into individual amino acids. Endopeptidases cleave peptide bonds within the peptide chain, while exopeptidases cleave peptide bonds at the ends of the chain. Peptide hydrolases are important in the medical field because they are involved in many diseases and conditions. For example, certain proteases are involved in the development of cancer, and inhibitors of these enzymes are being developed as potential cancer treatments. Peptide hydrolases are also involved in the immune response, and defects in these enzymes can lead to immune disorders. Additionally, peptide hydrolases are involved in the regulation of hormones, and imbalances in these enzymes can lead to hormonal disorders.

Peptidoglycan is a complex carbohydrate and protein molecule that forms the cell wall of most bacteria. It is composed of alternating units of sugars (N-acetylglucosamine and N-acetylmuramic acid) and peptides (short chains of amino acids) that are cross-linked together to form a strong, rigid structure. The peptidoglycan layer provides bacteria with structural support and protection against external stresses such as osmotic pressure and mechanical forces. It is also an important target for antibiotics, as many antibiotics work by disrupting the synthesis or integrity of the peptidoglycan layer, leading to bacterial cell lysis and death.

DNA transposable elements, also known as transposons, are segments of DNA that can move or transpose from one location in the genome to another. They are found in the genomes of many organisms, including plants, animals, and bacteria. In the medical field, DNA transposable elements are of interest because they can play a role in the evolution of genomes and the development of diseases. For example, some transposable elements can cause mutations in genes, which can lead to genetic disorders or cancer. Additionally, transposable elements can contribute to the evolution of new genes and the adaptation of organisms to changing environments. Transposable elements can also be used as tools in genetic research and biotechnology. For example, scientists can use transposable elements to insert genes into cells or organisms, allowing them to study the function of those genes or to create genetically modified organisms for various purposes.

In the medical field, "Bacteria, Aerobic" refers to a group of bacteria that require oxygen to survive and grow. These bacteria are commonly found in the environment and can cause a variety of infections in humans and animals when they enter the body. Aerobic bacteria are able to use oxygen as a terminal electron acceptor in their metabolic processes, which allows them to produce energy in the form of ATP. This is in contrast to anaerobic bacteria, which do not require oxygen and use other electron acceptors, such as nitrate or sulfate, to produce energy. Some common examples of aerobic bacteria include Streptococcus pneumoniae, Staphylococcus aureus, and Escherichia coli. These bacteria can cause a range of infections, including pneumonia, skin infections, and urinary tract infections. Treatment for infections caused by aerobic bacteria typically involves the use of antibiotics that are effective against these types of bacteria.

Immunoglobulin A, Secretory (IgA) is a type of antibody that is produced by plasma cells in the immune system. It is the most abundant antibody in the human body and is primarily found in the mucous membranes of the respiratory, gastrointestinal, and genitourinary tracts, as well as in breast milk. Secretory IgA plays an important role in protecting the body against infections and other harmful substances that may enter the body through the mucous membranes. It is able to neutralize viruses, bacteria, and other pathogens, and can also help to prevent them from adhering to the mucous membranes. In addition to its role in protecting the body against infections, secretory IgA has been shown to play a role in regulating the immune system and preventing autoimmune diseases. It is also important for the development of the immune system in infants, as it is present in high concentrations in breast milk and helps to protect the baby from infections. Overall, secretory IgA is an important component of the body's immune system and plays a crucial role in protecting the body against infections and other harmful substances.

In the medical field, "aza compounds" refers to a class of organic compounds that contain a nitrogen atom (N) in place of a carbon atom (C) in their molecular structure. These compounds are often used as drugs or as intermediates in the synthesis of drugs. Aza compounds can be further classified based on the functional groups present in their structure. For example, aza analogs of carboxylic acids are called aza acids, while aza analogs of alcohols are called aza alcohols. Some common examples of aza compounds used in medicine include azithromycin (an antibiotic), azacitidine (a chemotherapy drug), and azelaic acid (a skin care product). Aza compounds are often used in medicine because they can interact with biological molecules in unique ways, leading to new therapeutic effects. For example, azithromycin is effective against a wide range of bacterial infections because it inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Azacitidine, on the other hand, works by inhibiting DNA methyltransferases, which are enzymes involved in the regulation of gene expression.

In the medical field, "conjugation, genetic" refers to the transfer of genetic material from one bacterium to another through a process called conjugation. Conjugation is a form of bacterial reproduction that involves the transfer of genetic material, such as plasmids, from one bacterium to another through a pilus, which is a protein structure that extends from the surface of the bacterium. During conjugation, a donor bacterium transfers a plasmid to a recipient bacterium, which can then incorporate the genetic material into its own genome. This process can result in the transfer of antibiotic resistance genes, virulence factors, and other traits that can confer a selective advantage to the recipient bacterium. Conjugation is an important mechanism of bacterial evolution and has been studied extensively in the field of microbiology. It is also a potential target for the development of new antibiotics and other therapeutic strategies to combat bacterial infections.

Ciprofloxacin is an antibiotic medication that is used to treat a variety of bacterial infections, including urinary tract infections, respiratory infections, skin infections, and gastrointestinal infections. It is a fluoroquinolone antibiotic that works by inhibiting the growth and reproduction of bacteria. Ciprofloxacin is available in oral and intravenous forms, and it is typically prescribed for a specific duration of time, depending on the type and severity of the infection. It is important to take the medication exactly as prescribed by a healthcare provider, as stopping the medication too early can lead to the development of antibiotic-resistant bacteria. Common side effects of ciprofloxacin include nausea, diarrhea, headache, dizziness, and skin rash. In rare cases, it can cause more serious side effects, such as tendonitis or tendon rupture, and central nervous system problems. It is important to inform a healthcare provider of any other medications or medical conditions that may interact with ciprofloxacin.

Immunoglobulin G (IgG) is a type of protein that is produced by the immune system in response to the presence of foreign substances, such as bacteria, viruses, and toxins. It is the most abundant type of immunoglobulin in the blood and is responsible for the majority of the body's defense against infections. IgG is produced by B cells, which are a type of white blood cell that plays a key role in the immune response. When a B cell encounters a foreign substance, it produces IgG antibodies that can recognize and bind to the substance, marking it for destruction by other immune cells. IgG antibodies can also be transferred from mother to child through the placenta during pregnancy, providing the baby with some protection against infections during the first few months of life. In addition, some vaccines contain IgG antibodies to help stimulate the immune system and provide protection against specific diseases. Overall, IgG is an important component of the immune system and plays a critical role in protecting the body against infections and diseases.

Lactams are a class of organic compounds that contain a six-membered ring with an amide group (-CONH-) attached to one of the carbon atoms. They are commonly found in nature and are also synthesized in the laboratory for use in medicine. In the medical field, lactams are used as antibiotics to treat a variety of bacterial infections. The most well-known lactam antibiotics are penicillins, which contain a beta-lactam ring. Other examples of lactam antibiotics include cephalosporins, monobactams, and carbapenems. Lactams are effective against a wide range of bacteria, including gram-positive and gram-negative bacteria. They work by inhibiting the production of cell walls in bacteria, leading to cell lysis and death. However, like all antibiotics, lactams can also have side effects and can lead to the development of antibiotic resistance if not used properly.

Streptomycin is an antibiotic medication that is used to treat a variety of bacterial infections, including tuberculosis, pneumonia, and urinary tract infections. It works by inhibiting the growth of bacteria by interfering with their ability to produce proteins, which are essential for their survival. Streptomycin is typically administered intramuscularly or intravenously, and it is usually given in combination with other antibiotics to increase its effectiveness and reduce the risk of resistance. It is important to note that streptomycin can cause side effects, including hearing loss, kidney damage, and allergic reactions, and it should only be used under the supervision of a healthcare professional.

Carbohydrate metabolism refers to the series of chemical reactions that occur within cells to break down carbohydrates (such as glucose) into energy that can be used by the body. This process involves several metabolic pathways, including glycolysis, the citric acid cycle (also known as the Krebs cycle), and oxidative phosphorylation. During glycolysis, glucose is broken down into two molecules of pyruvate, which can then enter the citric acid cycle to produce energy in the form of ATP (adenosine triphosphate). The citric acid cycle also produces carbon dioxide and other metabolic intermediates that can be used in other metabolic pathways. Oxidative phosphorylation is the final stage of carbohydrate metabolism, in which the energy produced by the citric acid cycle is used to generate ATP through a process called chemiosmosis. This process occurs in the mitochondria of cells and is essential for the production of large amounts of energy that the body needs to function properly. Carbohydrate metabolism is closely regulated by hormones such as insulin and glucagon, which help to maintain blood glucose levels within a narrow range. Disorders of carbohydrate metabolism, such as diabetes, can result from defects in these regulatory mechanisms or from problems with the enzymes involved in carbohydrate metabolism.

Endocarditis, Subacute Bacterial is a type of infection that affects the inner lining of the heart (endocardium) and the heart valves. It is caused by bacteria that enter the bloodstream and attach themselves to the heart valves, causing inflammation and damage to the tissue. Subacute bacterial endocarditis typically occurs in people who have an existing heart condition, such as a heart valve defect or a history of rheumatic fever. Symptoms may include fever, chills, sweats, fatigue, and a new or changing heart murmur. Treatment typically involves antibiotics to kill the bacteria and surgery to repair or replace damaged heart valves.

Erysipelas is a bacterial skin infection that causes redness, swelling, and warmth in the affected area. It is caused by Streptococcus pyogenes bacteria and typically affects the skin on the face, neck, or limbs. The infection can spread quickly and can be severe, particularly in people with weakened immune systems or underlying medical conditions. Symptoms of erysipelas may include redness and swelling that extends beyond the area of the initial infection, fever, chills, and fatigue. Treatment typically involves antibiotics to clear the infection and pain relief medication to manage symptoms. In severe cases, hospitalization may be necessary.

Dextrans are a group of polysaccharides (complex carbohydrates) that are derived from cornstarch. They are used in a variety of medical applications, including as a thickening agent in intravenous fluids, as a diagnostic tool for measuring kidney function, and as a component of certain medications. Dextrans are also used in some medical devices, such as catheters and wound dressings. They are generally considered safe and well-tolerated, but like all medications and medical treatments, they can have potential side effects and risks.

Penicillin V is a type of antibiotic medication that is used to treat a variety of bacterial infections. It is a member of the penicillin family of antibiotics, which are derived from the mold Penicillium. Penicillin V is effective against a wide range of bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, and Haemophilus influenzae. It is often used to treat infections of the respiratory tract, such as pneumonia and bronchitis, as well as skin infections, urinary tract infections, and ear infections. Penicillin V is typically taken orally in the form of tablets or capsules. It works by inhibiting the growth of bacteria by interfering with the synthesis of their cell walls. This causes the bacteria to burst and die. Like all antibiotics, penicillin V can cause side effects, such as nausea, vomiting, diarrhea, and allergic reactions. It is important to take the medication exactly as prescribed by a healthcare provider and to complete the full course of treatment, even if symptoms improve before the medication is finished.

Hemolysin proteins are a group of toxins produced by certain bacteria that can cause damage to red blood cells (erythrocytes). These proteins are capable of disrupting the integrity of the cell membrane, leading to the release of hemoglobin, which can cause hemoglobinemia (an excess of hemoglobin in the blood) and hemoglobinuria (the presence of hemoglobin in the urine). Hemolysins can be classified into several types based on their mechanism of action and the target cells they affect. Some hemolysins, such as streptolysin O and pneumolysin, are pore-forming toxins that create holes in the cell membrane, leading to cell lysis and death. Other hemolysins, such as alpha-hemolysin, act by disrupting the cell membrane's lipid bilayer, leading to cell lysis. Hemolysins are produced by a variety of bacterial species, including Streptococcus pyogenes, Staphylococcus aureus, and Clostridium perfringens. Infections caused by these bacteria can lead to a range of symptoms, including fever, chills, nausea, vomiting, and abdominal pain. In severe cases, hemolysin production can lead to sepsis, a life-threatening condition characterized by widespread inflammation and organ dysfunction.

Pyruvate oxidase is an enzyme that catalyzes the oxidation of pyruvate to acetyl-CoA, carbon dioxide, and water. It is a key enzyme in the citric acid cycle, also known as the Krebs cycle or TCA cycle, which is the primary metabolic pathway for energy production in cells. Pyruvate oxidase is found in the mitochondria of cells and is involved in the production of ATP, the energy currency of the cell. It is also involved in the metabolism of amino acids and the detoxification of harmful substances. Pyruvate oxidase deficiency is a rare genetic disorder that can lead to a buildup of pyruvate in the body, which can cause a range of symptoms, including muscle weakness, developmental delays, and seizures.

Pyoderma is a general term used to describe any bacterial infection of the skin that leads to the formation of pus. It can be caused by a variety of bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa. Pyoderma can present in different forms, such as impetigo, cellulitis, and furuncles, and can affect people of all ages and demographics. Treatment typically involves the use of antibiotics to clear the infection and manage symptoms. In severe cases, hospitalization may be necessary.

Quinolones are a class of synthetic antibiotics that are commonly used to treat a variety of bacterial infections. They work by inhibiting the enzyme DNA gyrase, which is essential for bacterial DNA replication. This leads to the death of the bacteria and the resolution of the infection. Quinolones are available in both oral and injectable forms and are used to treat a wide range of infections, including respiratory tract infections, urinary tract infections, skin infections, and sexually transmitted infections. They are also commonly used to treat infections caused by certain types of bacteria that are resistant to other antibiotics. However, it is important to note that quinolones can have side effects, including nausea, diarrhea, headache, and skin rash. In some cases, they can also cause more serious side effects, such as tendonitis or tendon rupture, and an increased risk of developing certain types of infections, such as Clostridium difficile colitis. Therefore, it is important to use quinolones only as directed by a healthcare provider and to report any side effects that occur.

Autolysis is a process in which cells or tissues break down and degrade themselves. In the medical field, autolysis can occur as a result of injury, infection, or other factors that damage cells or tissues. Autolysis can be a normal process in the body, such as during the breakdown of dead or damaged cells in the immune response. However, excessive autolysis can lead to tissue damage and inflammation, which can contribute to the development of various medical conditions. In some cases, autolysis can be accelerated by the presence of enzymes or other substances that break down cell components. For example, during the decomposition of a dead body, the enzymes produced by bacteria and fungi can accelerate the process of autolysis, leading to the characteristic smell and appearance of a decaying body. In the medical field, autolysis can be a concern in situations where cells or tissues are damaged or injured, such as in traumatic injuries or surgical procedures. In these cases, efforts may be made to prevent or slow down the process of autolysis to minimize tissue damage and promote healing.

Anaerobiosis is a condition in which an organism cannot survive in the presence of oxygen. In the medical field, anaerobiosis is often associated with infections caused by anaerobic bacteria, which are bacteria that do not require oxygen to grow and survive. These bacteria are commonly found in the human body, particularly in areas such as the mouth, gut, and female reproductive tract, where oxygen levels are low. Anaerobic bacteria can cause a range of infections, including dental caries, periodontitis, and pelvic inflammatory disease. Treatment for anaerobic infections typically involves the use of antibiotics that are effective against anaerobic bacteria.

Glycosyltransferases are a group of enzymes that transfer sugar molecules (glycans) from a donor molecule to an acceptor molecule, forming a glycosidic bond. These enzymes play a crucial role in the biosynthesis of carbohydrates, which are essential components of many biological molecules, including proteins, lipids, and nucleic acids. In the medical field, glycosyltransferases are involved in various biological processes, including cell signaling, immune response, and cancer development. For example, some glycosyltransferases are involved in the synthesis of glycans on the surface of cells, which can affect their interactions with other cells and the immune system. Dysregulation of glycosyltransferases has been implicated in several diseases, including cancer, autoimmune disorders, and infectious diseases. Glycosyltransferases are also important targets for drug discovery, as they play a role in the metabolism of many drugs and toxins. Inhibitors of specific glycosyltransferases have been developed as potential therapeutic agents for a variety of diseases, including cancer, viral infections, and inflammatory disorders.

Gram-positive bacterial infections are infections caused by bacteria that stain positively with the Gram stain, a common laboratory test used to differentiate between different types of bacteria. Gram-positive bacteria have a thick peptidoglycan layer in their cell walls, which stains pink or purple with the Gram stain. Gram-positive bacterial infections can affect various parts of the body, including the skin, respiratory system, urinary tract, and bloodstream. Some common examples of gram-positive bacterial infections include strep throat, pneumonia, cellulitis, and endocarditis. Treatment for gram-positive bacterial infections typically involves the use of antibiotics, which are medications that can kill or inhibit the growth of bacteria. The choice of antibiotic will depend on the specific type of bacteria causing the infection and the severity of the infection. In some cases, hospitalization may be necessary for more severe infections.

Chlorhexidine is an antiseptic agent that is commonly used in the medical field for a variety of purposes. It is a broad-spectrum disinfectant that is effective against a wide range of microorganisms, including bacteria, viruses, and fungi. Chlorhexidine is available in a variety of forms, including solutions, gels, and mouthwashes. It is often used to clean and disinfect surfaces and equipment in healthcare settings, as well as to treat wounds and skin infections. It is also commonly used as an antiseptic mouthwash to help prevent gum disease and tooth decay. Chlorhexidine works by disrupting the cell membranes of microorganisms, which kills them or prevents them from multiplying. It is generally considered to be safe and effective when used as directed, although it can cause skin irritation and allergic reactions in some people. It is important to follow the instructions for use carefully and to avoid using chlorhexidine on open wounds or in the eyes.

Skin diseases, infectious, refer to a group of medical conditions that affect the skin and are caused by the invasion of microorganisms such as bacteria, viruses, fungi, and parasites. These infections can cause a range of symptoms, including redness, swelling, itching, pain, and the formation of sores or ulcers. Some common examples of infectious skin diseases include acne, impetigo, ringworm, athlete's foot, and chickenpox. These conditions can be treated with antibiotics, antifungal medications, or antiviral drugs, depending on the specific cause of the infection. In addition to medical treatment, it is important to practice good hygiene to prevent the spread of infectious skin diseases. This includes washing your hands regularly, avoiding close contact with people who are sick, and keeping your skin clean and dry.

Glucose is a simple sugar that is a primary source of energy for the body's cells. It is also known as blood sugar or dextrose and is produced by the liver and released into the bloodstream by the pancreas. In the medical field, glucose is often measured as part of routine blood tests to monitor blood sugar levels in people with diabetes or those at risk of developing diabetes. High levels of glucose in the blood, also known as hyperglycemia, can lead to a range of health problems, including heart disease, nerve damage, and kidney damage. On the other hand, low levels of glucose in the blood, also known as hypoglycemia, can cause symptoms such as weakness, dizziness, and confusion. In severe cases, it can lead to seizures or loss of consciousness. In addition to its role in energy metabolism, glucose is also used as a diagnostic tool in medical testing, such as in the measurement of blood glucose levels in newborns to detect neonatal hypoglycemia.

Hyaluronoglucosaminidase (also known as hyaluronidase) is an enzyme that breaks down hyaluronic acid, a complex carbohydrate found in the extracellular matrix of connective tissue. It is primarily produced by cells in the immune system, such as neutrophils and macrophages, and is involved in the process of inflammation. In the medical field, hyaluronoglucosaminidase is used as a diagnostic tool to detect and monitor certain diseases, such as cancer, rheumatoid arthritis, and osteoarthritis. It is also used in certain medical procedures, such as tissue repair and wound healing, to break down hyaluronic acid and facilitate the migration of cells to the site of injury. In addition, hyaluronoglucosaminidase has been studied for its potential therapeutic applications in various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. However, more research is needed to fully understand its role in these conditions and to develop effective treatments.

Bacteriophages, also known as phages, are viruses that specifically infect and replicate within bacteria. They are one of the most abundant biological entities on the planet and are found in virtually every environment where bacteria exist. In the medical field, bacteriophages have been studied for their potential use as an alternative to antibiotics in the treatment of bacterial infections. Unlike antibiotics, which target all types of bacteria, bacteriophages are highly specific and only infect and kill the bacteria they are designed to target. This makes them a promising option for treating antibiotic-resistant bacterial infections, which are becoming increasingly common. Bacteriophages have also been used in research to study bacterial genetics and to develop new vaccines. In addition, they have been proposed as a way to control bacterial populations in industrial settings, such as food processing plants and water treatment facilities. Overall, bacteriophages have the potential to play an important role in the treatment and prevention of bacterial infections, and ongoing research is exploring their potential applications in medicine and other fields.

Puerperal infection, also known as postpartum infection, is an infection that occurs in the reproductive tract of a woman during or after childbirth. It can affect the uterus, vagina, cervix, or other parts of the reproductive system. Puerperal infection is a serious medical condition that can lead to complications such as sepsis, abscesses, and even death if left untreated. It is caused by bacteria that can enter the reproductive tract during childbirth, or by bacteria that are already present in the body but become more virulent after childbirth. Risk factors for puerperal infection include prolonged labor, multiple pregnancies, and certain medical conditions such as diabetes or hypertension. Treatment typically involves antibiotics and supportive care, and may require hospitalization.

Pneumonia, bacterial is a type of pneumonia caused by bacteria. It is an infection that affects the lungs and can cause symptoms such as cough, fever, chest pain, and difficulty breathing. Bacterial pneumonia is usually more serious than viral pneumonia and can be life-threatening if left untreated. It is typically treated with antibiotics, which can help to kill the bacteria causing the infection and relieve symptoms. In some cases, hospitalization may be necessary for severe cases of bacterial pneumonia.

Cefuroxime is an antibiotic medication that belongs to the cephalosporin class of drugs. It is used to treat a variety of bacterial infections, including respiratory tract infections, ear infections, urinary tract infections, and skin infections. Cefuroxime works by inhibiting the growth of bacteria, which helps to eliminate the infection. It is usually taken orally in the form of tablets or capsules, and the dosage and duration of treatment will depend on the specific infection being treated and the patient's medical condition. It is important to follow the instructions of your healthcare provider when taking cefuroxime and to complete the full course of treatment, even if you start to feel better before the medication is finished.

Azithromycin is an antibiotic medication that is used to treat a variety of bacterial infections, including respiratory tract infections, ear infections, skin infections, and sexually transmitted infections. It is a type of macrolide antibiotic, which works by stopping the growth of bacteria. Azithromycin is available in both oral and injectable forms, and it is typically taken once daily for a short period of time, usually 5 days. It is generally well-tolerated by most people, although it can cause side effects such as nausea, diarrhea, and stomach pain. It is important to note that azithromycin is only effective against bacterial infections and will not work against viral infections such as the flu or COVID-19. It is also important to complete the full course of treatment, even if symptoms improve before the medication is finished, to ensure that the infection is fully treated and to prevent the development of antibiotic-resistant bacteria.

Amoxicillin is an antibiotic medication that is commonly used to treat a variety of bacterial infections, including pneumonia, bronchitis, ear infections, urinary tract infections, and skin infections. It is a type of penicillin antibiotic that works by stopping the growth of bacteria in the body. Amoxicillin is usually taken orally in the form of tablets or capsules, and it is often prescribed for short-term use. It is important to follow the dosage instructions provided by your healthcare provider and to complete the full course of treatment, even if you start to feel better before the medication is finished. Like all antibiotics, amoxicillin can cause side effects, such as nausea, diarrhea, and allergic reactions. It is important to let your healthcare provider know if you experience any side effects while taking amoxicillin.

Bacterial load refers to the number of bacteria present in a particular sample or tissue. It is commonly used in the medical field to assess the severity of bacterial infections and to monitor the effectiveness of antibiotic treatments. Bacterial load can be measured using various techniques, including culture-based methods, molecular techniques such as polymerase chain reaction (PCR), and imaging techniques such as computed tomography (CT) scans or magnetic resonance imaging (MRI). A high bacterial load is typically associated with more severe infections and a greater risk of complications, while a low bacterial load may indicate a milder infection or successful treatment with antibiotics. However, the interpretation of bacterial load can be complex and may depend on the specific type of bacteria, the location of the infection, and other factors.

Aerobiosis is a type of respiration that occurs in the presence of oxygen. In the medical field, aerobiosis is the process by which cells in the body use oxygen to produce energy through a series of chemical reactions called cellular respiration. This process is essential for the survival of most living organisms, as it provides the energy needed for growth, repair, and other vital functions. During aerobiosis, glucose (a type of sugar) is broken down into carbon dioxide and water, releasing energy in the form of ATP (adenosine triphosphate), which is the primary energy currency of the cell. Oxygen is required for this process to occur, as it acts as the final electron acceptor in the electron transport chain, which is the final step in cellular respiration. Aerobic exercise, such as running or cycling, is a type of physical activity that relies on aerobiosis to produce energy. During aerobic exercise, the body uses oxygen to break down glucose and other nutrients, producing energy that can be used to power the muscles and other organs. Regular aerobic exercise has been shown to have numerous health benefits, including improved cardiovascular health, increased endurance, and weight loss.

Haemophilus infections are a group of bacterial infections caused by the bacterium Haemophilus influenzae. These infections can affect various parts of the body, including the respiratory tract, joints, and bloodstream. Haemophilus influenzae is a common cause of respiratory tract infections, such as bronchitis and pneumonia, particularly in children. It can also cause ear infections, meningitis, and sepsis. There are two main types of Haemophilus influenzae: type b (Hib) and non-type b (NTHi). Hib is the most serious type and can cause severe infections, including meningitis and sepsis, particularly in young children. NTHi is less serious but can still cause respiratory tract infections and other illnesses. Haemophilus infections are typically treated with antibiotics, such as amoxicillin or ceftriaxone. Vaccines are available to prevent Hib infections, but not NTHi infections. It is important to seek medical attention if you suspect you or someone you know may have a Haemophilus infection, as prompt treatment is crucial for a successful outcome.

Community-acquired infections (CAIs) are infections that are acquired by an individual in the community, rather than in a healthcare setting. These infections can be caused by a variety of microorganisms, including bacteria, viruses, fungi, and parasites. CAIs can be transmitted through various means, such as person-to-person contact, contaminated food or water, or contact with contaminated surfaces. Examples of CAIs include the common cold, influenza, pneumonia, urinary tract infections, and skin infections. These infections can be treated with antibiotics, antiviral medications, or antifungal medications, depending on the specific cause of the infection. It is important to note that CAIs can be serious and can lead to hospitalization or even death, particularly in vulnerable populations such as the elderly, young children, and people with weakened immune systems.

Chloramphenicol is an antibiotic medication that is used to treat a variety of bacterial infections, including pneumonia, typhoid fever, and urinary tract infections. It works by stopping the growth of bacteria in the body. Chloramphenicol is available in both oral and injectable forms and is typically prescribed by a healthcare provider. It is important to note that chloramphenicol may not be effective against all types of bacteria and can cause serious side effects, including bone marrow suppression and allergic reactions. Therefore, it should only be used under the guidance of a healthcare provider.

Virginiamycin is a type of antibiotic that is used in the medical field to treat bacterial infections. It is a member of the class of antibiotics known as aminoglycosides, which work by binding to bacterial ribosomes and inhibiting protein synthesis. Virginiamycin is primarily used to treat infections in livestock, such as cattle and poultry, but it has also been used in humans in some cases. It is available in both oral and injectable forms and is typically used to treat infections of the respiratory tract, skin, and gastrointestinal tract.

Galactose is a simple sugar that is a component of the disaccharide lactose, which is found in milk and other dairy products. In the medical field, galactose is often studied in relation to its role in the metabolism of carbohydrates and its potential health effects. Galactose is a monosaccharide, which means that it is a single unit of sugar. It is a reducing sugar, which means that it can undergo a chemical reaction called oxidation that can be used to identify it. In the body, galactose is broken down and converted into glucose, which is used for energy. However, if galactose is not properly metabolized, it can build up in the blood and cause a condition called galactosemia. Galactosemia is a rare genetic disorder that occurs when the body is unable to properly break down galactose, leading to a buildup of galactose in the blood and other tissues. Galactose is also used in the production of certain foods and beverages, such as yogurt and some types of soft drinks. It is also used in the production of certain medications and other chemicals.

Membrane proteins are proteins that are embedded within the lipid bilayer of a cell membrane. They play a crucial role in regulating the movement of substances across the membrane, as well as in cell signaling and communication. There are several types of membrane proteins, including integral membrane proteins, which span the entire membrane, and peripheral membrane proteins, which are only in contact with one or both sides of the membrane. Membrane proteins can be classified based on their function, such as transporters, receptors, channels, and enzymes. They are important for many physiological processes, including nutrient uptake, waste elimination, and cell growth and division.

Anaerobic bacteria are a group of microorganisms that do not require oxygen to survive and grow. They are commonly found in environments that are low in oxygen, such as the human digestive tract, soil, and water. Anaerobic bacteria can be either obligate anaerobes, which means they cannot survive in the presence of oxygen, or facultative anaerobes, which can survive in both oxygen-rich and oxygen-poor environments. In the medical field, anaerobic bacteria are often associated with infections, particularly those that occur in the gastrointestinal tract, female reproductive system, and oral cavity. Some common examples of anaerobic bacteria that can cause infections include Bacteroides fragilis, Clostridium difficile, and Peptostreptococcus micros. These bacteria can cause a range of infections, from mild to severe, and can be difficult to treat because they are resistant to many antibiotics.

Horse diseases refer to any illness or condition that affects horses. These diseases can be caused by a variety of factors, including viruses, bacteria, fungi, parasites, genetics, nutrition, and environmental factors. Some common horse diseases include equine influenza, equine herpesvirus, equine colic, laminitis, founder, tetanus, botulism, and various types of worms and parasites. Horse diseases can range from mild to severe and can affect the horse's overall health, performance, and quality of life. Treatment for horse diseases may involve medications, surgery, and other medical interventions, as well as changes to the horse's diet and environment to promote healing and prevent recurrence.

DNA, ribosomal, refers to the specific type of DNA found within ribosomes, which are the cellular structures responsible for protein synthesis. Ribosomal DNA (rDNA) is transcribed into ribosomal RNA (rRNA), which then forms the core of the ribosome. The rRNA molecules are essential for the assembly and function of the ribosome, and the rDNA sequences that code for these molecules are highly conserved across different species. Mutations in rDNA can lead to defects in ribosome function and can be associated with various medical conditions, including some forms of cancer and inherited disorders.

Cariogenic agents are substances that promote tooth decay (caries) by promoting the growth of harmful bacteria in the mouth. These agents include carbohydrates, such as sugars and starches, which are broken down by bacteria in the mouth and produce acids that can erode tooth enamel. Other cariogenic agents include certain types of bacteria, such as Streptococcus mutans, which produce acids that can damage tooth enamel and lead to cavities. In the medical field, cariogenic agents are an important factor to consider in the prevention and treatment of tooth decay.

Chloramphenicol resistance refers to the ability of bacteria to resist the effects of the antibiotic chloramphenicol. Chloramphenicol is an antibiotic that is commonly used to treat a variety of bacterial infections, including pneumonia, typhoid fever, and urinary tract infections. However, some bacteria have developed resistance to chloramphenicol through the production of enzymes that inactivate the antibiotic or by altering the target site of the antibiotic. Chloramphenicol resistance can be acquired through genetic mutations or by horizontal gene transfer, in which bacteria acquire resistance genes from other bacteria. The development of resistance to chloramphenicol and other antibiotics is a major concern in the medical field because it can lead to the spread of antibiotic-resistant bacteria and make it more difficult to treat infections.

Cellulitis is a bacterial infection that affects the skin and the tissue just beneath the skin. It is characterized by redness, swelling, warmth, and pain in the affected area. The infection usually starts as a small red bump or pimple that quickly becomes larger and more painful. It can also spread to nearby lymph nodes and cause fever and fatigue. Cellulitis is most commonly caused by Streptococcus pyogenes, a type of bacteria that is commonly found in the throat and on the skin. Other bacteria, such as Staphylococcus aureus, can also cause cellulitis. Treatment for cellulitis typically involves antibiotics to kill the bacteria causing the infection. In severe cases, hospitalization may be necessary. It is important to seek medical attention promptly if you suspect you have cellulitis, as it can spread quickly and cause serious complications if left untreated.

Durapatite is a synthetic bone substitute material that is used in orthopedic and dental surgeries. It is a type of calcium phosphate ceramic that is similar in composition to natural bone and is designed to promote bone growth and regeneration. Durapatite is typically used in procedures such as bone grafting, where it is placed in the body to help fill in gaps or defects in bone tissue. It can also be used as an alternative to autografts (bone taken from the patient's own body) or allografts (bone taken from a donor) in certain cases. Durapatite has several advantages over other bone substitute materials, including its ability to promote bone growth and its biocompatibility with the body. It is also relatively easy to shape and can be customized to fit the specific needs of each patient. Overall, Durapatite is a useful tool for surgeons and dentists who are looking for a safe and effective way to promote bone growth and regeneration in the body.

Pregnancy complications, infectious refers to medical conditions that arise during pregnancy due to infections. These infections can be caused by bacteria, viruses, fungi, or parasites and can have serious consequences for both the mother and the developing fetus. Some common infectious complications of pregnancy include: 1. Urinary tract infections (UTIs): These infections can cause discomfort and pain, but with prompt treatment, they usually do not cause harm to the fetus. 2. Group B streptococcus (GBS) infection: This is a type of bacteria that can cause serious infections in newborns, including meningitis and pneumonia. Women who are pregnant or have recently given birth are screened for GBS and treated with antibiotics if they are found to be carrying the bacteria. 3. Toxoplasmosis: This is an infection caused by the parasite Toxoplasma gondii, which can be transmitted to the fetus through the placenta. It can cause miscarriage, stillbirth, or serious birth defects if left untreated. 4. Rubella (German measles): This is a viral infection that can cause serious birth defects if a pregnant woman is infected during the first trimester of pregnancy. 5. Syphilis: This is a bacterial infection that can be transmitted to the fetus through the placenta and cause serious birth defects if left untreated. Prompt diagnosis and treatment of infectious complications of pregnancy are crucial to ensure the health and well-being of both the mother and the developing fetus.

Child Day Care Centers are facilities that provide care and supervision for children during the day, typically for working parents or those who need temporary childcare. These centers are designed to meet the physical, emotional, social, and intellectual needs of children in a safe and nurturing environment. They may offer a range of activities and programs, including educational and recreational activities, to promote the development and well-being of children. In the medical field, Child Day Care Centers may be used as a setting for research studies or as a place for children to receive medical care or therapy.

Blood bactericidal activity refers to the ability of the immune system to destroy and eliminate bacteria present in the bloodstream. This process is primarily carried out by white blood cells, such as neutrophils and monocytes, which release enzymes and other substances that can break down and kill bacteria. The blood bactericidal activity is an important defense mechanism against bacterial infections that can spread throughout the body and cause serious illness or even death. It is also a key factor in determining the outcome of sepsis, a life-threatening condition that occurs when the body's response to an infection leads to widespread inflammation and organ damage. In medical research, blood bactericidal activity is often measured in vitro, using laboratory cultures of bacteria and blood samples from patients. This can help researchers understand how the immune system responds to different types of bacteria and identify potential targets for new treatments.

Ampicillin is a type of antibiotic medication that is used to treat a variety of bacterial infections. It is a penicillin antibiotic, which means that it works by inhibiting the growth of bacteria by interfering with their ability to make cell walls. Ampicillin is effective against a wide range of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Escherichia coli. It is often used to treat infections of the respiratory tract, urinary tract, and skin and soft tissues. Ampicillin is usually administered orally or intravenously, and it is generally well-tolerated by most people. However, like all antibiotics, it can cause side effects such as nausea, diarrhea, and allergic reactions.

Vancomycin is an antibiotic medication that is used to treat a variety of bacterial infections, including severe skin infections, pneumonia, and bloodstream infections. It is particularly effective against bacteria that are resistant to other antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin works by inhibiting the growth of bacteria by interfering with the synthesis of their cell walls. It is typically administered intravenously, although it can also be given orally in some cases. Vancomycin is a powerful antibiotic, and it is important to use it only when it is necessary and to follow the prescribed dosage and duration of treatment. Overuse or misuse of vancomycin can lead to the development of antibiotic-resistant bacteria, which can be more difficult to treat.

Nasopharyngeal diseases refer to medical conditions that affect the nasopharynx, which is the upper part of the throat that connects the nasal cavity to the pharynx. The nasopharynx is a complex and important structure that plays a crucial role in breathing, swallowing, and speech. Nasopharyngeal diseases can be classified into two main categories: infectious and non-infectious. Infectious nasopharyngeal diseases are caused by viruses, bacteria, or fungi, and can include conditions such as the common cold, influenza, strep throat, and tonsillitis. Non-infectious nasopharyngeal diseases, on the other hand, are not caused by microorganisms and can include conditions such as nasopharyngeal cancer, nasal polyps, and rhinosinusitis. Symptoms of nasopharyngeal diseases can vary depending on the specific condition, but may include nasal congestion, runny nose, sore throat, cough, fever, and difficulty breathing. Treatment for nasopharyngeal diseases depends on the underlying cause and may include medications, surgery, or other interventions. Early detection and treatment are important for preventing complications and improving outcomes.

'Anti-Infective Agents, Local' refers to medications that are applied directly to a specific area of the body to treat or prevent infections. These agents are typically used to treat skin infections, ear infections, eye infections, and other localized infections. They work by killing or inhibiting the growth of bacteria, viruses, fungi, or other microorganisms that cause infections. Examples of local anti-infective agents include antibiotics such as neomycin, polymyxin B, and bacitracin, which are commonly used to treat skin infections. Other examples include antifungal agents such as clotrimazole and miconazole, which are used to treat fungal infections of the skin, nails, and scalp. Local anti-infective agents are often available in the form of creams, ointments, gels, or solutions that can be applied directly to the affected area.

In the medical field, "Shock, Septic" refers to a severe and life-threatening condition that occurs when the body's immune system overreacts to an infection, leading to widespread inflammation and damage to organs and tissues. Septic shock is a type of sepsis, which is a condition that occurs when the body's response to an infection causes inflammation throughout the body. In septic shock, the immune system releases large amounts of chemicals that cause blood vessels to narrow and blood pressure to drop, leading to reduced blood flow to vital organs such as the heart, brain, and kidneys. Symptoms of septic shock may include fever, chills, rapid heartbeat, rapid breathing, confusion, and decreased urine output. Treatment for septic shock typically involves antibiotics to treat the underlying infection, fluids and medications to maintain blood pressure and oxygen levels, and supportive care to manage symptoms and prevent complications.,。

An abscess is a localized collection of pus that forms in the body as a result of an infection. It is typically caused by bacteria or other microorganisms that enter the body through a wound or other opening, such as a tooth cavity or a surgical incision. The body's immune system responds to the infection by sending white blood cells to the area, which can lead to the formation of an abscess. Abscesses can occur in many different parts of the body, including the skin, muscles, joints, and organs. They can be painful and may cause redness, swelling, and warmth in the affected area. If left untreated, abscesses can become infected and spread to other parts of the body, potentially causing serious complications. Treatment for abscesses typically involves draining the pus and removing any infected tissue. This may be done through a surgical incision or by using a needle to drain the abscess. Antibiotics may also be prescribed to help fight the infection. In some cases, the abscess may recur if the underlying cause of the infection is not treated.

Salivary proteins and peptides are molecules that are secreted by the salivary glands and are present in saliva. They play important roles in various aspects of oral health and function, including lubrication of the mouth, protection against bacterial and viral infections, and digestion of food. Some of the major classes of salivary proteins and peptides include mucins, amylase, lipase, lysozyme, lactoferrin, and histatins. Mucins are large, complex glycoproteins that help to lubricate and protect the oral mucosa, while amylase and lipase are digestive enzymes that break down carbohydrates and fats in food. Lysozyme is an antimicrobial protein that helps to protect against bacterial infections, while lactoferrin and histatins have antimicrobial and anti-inflammatory properties. Abnormal levels or function of salivary proteins and peptides can be associated with various oral and systemic diseases, such as dry mouth, periodontal disease, and cancer. Therefore, the study of salivary proteins and peptides is an important area of research in the medical field.

In the medical field, "Disease Models, Animal" refers to the use of animals to study and understand human diseases. These models are created by introducing a disease or condition into an animal, either naturally or through experimental manipulation, in order to study its progression, symptoms, and potential treatments. Animal models are used in medical research because they allow scientists to study diseases in a controlled environment and to test potential treatments before they are tested in humans. They can also provide insights into the underlying mechanisms of a disease and help to identify new therapeutic targets. There are many different types of animal models used in medical research, including mice, rats, rabbits, dogs, and monkeys. Each type of animal has its own advantages and disadvantages, and the choice of model depends on the specific disease being studied and the research question being addressed.

Infectious arthritis is a type of arthritis that is caused by an infection in the joints. It can be caused by bacteria, viruses, fungi, or other microorganisms that enter the joint and cause inflammation and damage to the joint lining and cartilage. Symptoms of infectious arthritis may include joint pain, swelling, redness, warmth, and stiffness, as well as fever, chills, and fatigue. Treatment typically involves antibiotics to treat the underlying infection, as well as pain relief and physical therapy to help restore joint function. In severe cases, surgery may be necessary to remove damaged tissue or drain an abscess.

Chromosomes, bacterial, refer to the genetic material of bacteria, which are typically circular DNA molecules. Unlike eukaryotic cells, which have linear chromosomes, bacterial chromosomes are circular and can range in size from a few thousand to several million base pairs. Bacterial chromosomes contain all the genetic information necessary for the bacterium to grow, reproduce, and carry out its various functions. In addition to the bacterial chromosome, bacteria may also have plasmids, which are smaller, circular pieces of DNA that can be transferred between bacteria and may carry genes that confer advantageous traits such as antibiotic resistance.

In the medical field, the term "cattle" refers to large domesticated animals that are raised for their meat, milk, or other products. Cattle are a common source of food and are also used for labor in agriculture, such as plowing fields or pulling carts. In veterinary medicine, cattle are often referred to as "livestock" and may be treated for a variety of medical conditions, including diseases, injuries, and parasites. Some common medical issues that may affect cattle include respiratory infections, digestive problems, and musculoskeletal disorders. Cattle may also be used in medical research, particularly in the fields of genetics and agriculture. For example, scientists may study the genetics of cattle to develop new breeds with desirable traits, such as increased milk production or resistance to disease.

In the medical field, suppuration refers to the process by which pus is formed and discharged from a wound or infected area of the body. Pus is a thick, yellowish-white fluid that contains white blood cells, dead tissue, and bacteria. Suppuration is a natural response of the body's immune system to fight off infection. It helps to remove harmful bacteria and other microorganisms from the body and prevent the spread of infection. However, excessive or prolonged suppuration can be a sign of a more serious infection and may require medical intervention, such as the use of antibiotics or drainage of the infected area.

Immunoglobulin A (IgA) is a type of antibody that plays a crucial role in the body's immune system. It is the most abundant antibody in the mucous membranes, which line the surfaces of the respiratory, gastrointestinal, and genitourinary tracts. IgA is produced by plasma cells in the bone marrow and is secreted into the bloodstream and mucous membranes. It is particularly important in protecting against infections in the respiratory and gastrointestinal tracts, where it helps to neutralize and eliminate pathogens such as bacteria, viruses, and fungi. IgA can also be found in tears, saliva, and breast milk, where it provides protection against infections in the eyes, mouth, and digestive tract. In addition, IgA plays a role in the immune response to certain types of cancer and autoimmune diseases. Overall, IgA is a critical component of the body's immune system and plays a vital role in protecting against infections and diseases.

In the medical field, "cheese" is not a commonly used term. However, there are some medical conditions that may be referred to as "cheese-like" or "cheesy" in appearance or texture. One example is a condition called "cheesy pustules," which is a type of skin lesion that can occur in certain skin infections, such as impetigo or folliculitis. These lesions are characterized by a yellowish-white, pus-filled bump that may be surrounded by redness and swelling. Another example is "cheesy brain," which is a term used to describe a type of brain injury called diffuse axonal injury. This type of injury occurs when the brain is subjected to a sudden, violent force, such as a car accident or a sports injury. The injury can cause damage to the brain's axons, which are the long, slender fibers that transmit signals between nerve cells. The damaged axons can become tangled and twisted, creating a "cheesy" appearance on an MRI scan of the brain. Overall, while "cheese" is not a commonly used term in the medical field, there are some medical conditions that may be referred to as "cheesy" in appearance or texture.

DNA primers are short, single-stranded DNA molecules that are used in a variety of molecular biology techniques, including polymerase chain reaction (PCR) and DNA sequencing. They are designed to bind to specific regions of a DNA molecule, and are used to initiate the synthesis of new DNA strands. In PCR, DNA primers are used to amplify specific regions of DNA by providing a starting point for the polymerase enzyme to begin synthesizing new DNA strands. The primers are complementary to the target DNA sequence, and are added to the reaction mixture along with the DNA template, nucleotides, and polymerase enzyme. The polymerase enzyme uses the primers as a template to synthesize new DNA strands, which are then extended by the addition of more nucleotides. This process is repeated multiple times, resulting in the amplification of the target DNA sequence. DNA primers are also used in DNA sequencing to identify the order of nucleotides in a DNA molecule. In this application, the primers are designed to bind to specific regions of the DNA molecule, and are used to initiate the synthesis of short DNA fragments. The fragments are then sequenced using a variety of techniques, such as Sanger sequencing or next-generation sequencing. Overall, DNA primers are an important tool in molecular biology, and are used in a wide range of applications to study and manipulate DNA.

Amoxicillin-Potassium Clavulanate Combination is a medication used to treat bacterial infections. It is a combination of two antibiotics: amoxicillin and potassium clavulanate. Amoxicillin is a penicillin antibiotic that works by stopping the growth of bacteria, while potassium clavulanate is a beta-lactamase inhibitor that helps protect amoxicillin from being broken down by bacteria's enzymes. This combination is often used to treat respiratory tract infections, ear infections, skin infections, and urinary tract infections. It is usually taken orally in the form of tablets or capsules.

In the medical field, carbohydrates are one of the three macronutrients that provide energy to the body. They are made up of carbon, hydrogen, and oxygen atoms and are found in foods such as grains, fruits, vegetables, and dairy products. Carbohydrates are broken down into glucose (a simple sugar) during digestion and are then transported to cells throughout the body to be used as energy. The body can store excess glucose as glycogen in the liver and muscles for later use. There are two main types of carbohydrates: simple and complex. Simple carbohydrates, also known as sugars, are made up of one or two sugar molecules and are quickly digested and absorbed by the body. Complex carbohydrates, on the other hand, are made up of many sugar molecules and take longer to digest and absorb. In the medical field, carbohydrates are often discussed in the context of nutrition and diabetes management. People with diabetes need to carefully monitor their carbohydrate intake to help manage their blood sugar levels.

Endocarditis is a serious infection that affects the inner lining of the heart, known as the endocardium. It can occur when bacteria, fungi, or other microorganisms enter the bloodstream and attach themselves to the heart valves or other areas of the heart. Endocarditis can cause inflammation, damage, and scarring of the heart tissue, which can lead to serious complications such as heart failure, stroke, and even death. Endocarditis can be classified into two main types: acute and chronic. Acute endocarditis typically develops rapidly and is often caused by a bacterial infection. Chronic endocarditis, on the other hand, develops slowly over time and is often caused by a fungal or nonbacterial infection. Endocarditis is typically diagnosed through a combination of medical history, physical examination, and diagnostic tests such as blood cultures, echocardiography, and imaging studies. Treatment for endocarditis typically involves antibiotics to kill the microorganisms causing the infection, as well as surgery to repair or replace damaged heart valves.

Muramidase is an enzyme that is involved in the degradation of peptidoglycan, a major component of bacterial cell walls. It is also known as lysozyme or muramidase lysozyme. The enzyme cleaves the bond between the N-acetylglucosamine and N-acetylmuramic acid residues in the peptidoglycan chain, leading to the breakdown of the cell wall and ultimately the death of the bacterium. Muramidase is found in various organisms, including humans, and is used as an antimicrobial agent in some medications. It is also used in laboratory research to study bacterial cell wall structure and function.

Lectins are a class of proteins that are found in many plants, animals, and microorganisms. They are characterized by their ability to bind to specific carbohydrates, such as sugars and starches, on the surface of cells. In the medical field, lectins have been studied for their potential therapeutic applications. For example, some lectins have been shown to have antiviral, antibacterial, and antifungal properties, and may be useful in the development of new drugs to treat infections. Lectins have also been used as research tools to study cell-cell interactions and to identify specific cell surface markers. In addition, some lectins have been used in diagnostic tests to detect specific diseases or conditions, such as cancer or diabetes. However, it is important to note that not all lectins are safe or effective for medical use, and some may even be toxic. Therefore, the use of lectins in medicine requires careful consideration and testing to ensure their safety and efficacy.

Carnobacteriaceae is a family of Gram-positive bacteria that are commonly found in a variety of environments, including soil, water, and food. In the medical field, Carnobacteriaceae are of interest because some species of these bacteria can cause foodborne illness in humans. For example, Carnobacterium divergens has been associated with infections in immunocompromised individuals, while Carnobacterium maltaromaticum has been linked to spoilage of certain foods. In general, however, Carnobacteriaceae are considered to be low-virulence bacteria and are not typically associated with serious illness in healthy individuals.

Fimbriae proteins are protein structures found on the surface of certain bacteria. They are thin, hair-like projections that extend from the bacterial cell surface and are involved in the attachment of bacteria to surfaces, including host cells and other bacteria. Fimbriae proteins play an important role in the pathogenesis of many bacterial infections, as they allow bacteria to adhere to and colonize host tissues. They are also involved in the transfer of genetic material between bacteria, as well as in the movement of bacteria across surfaces. In the medical field, fimbriae proteins are of interest as potential targets for the development of new antibacterial therapies.

In the medical field, acids are substances that donate hydrogen ions (H+) when dissolved in water. They are classified as either strong or weak acids, depending on how completely they ionize in water. Acids can have various effects on the body, depending on their concentration and duration of exposure. For example, hydrochloric acid (HCl) is a strong acid that is produced by the stomach to help break down food. However, if the stomach produces too much HCl, it can cause acid reflux, heartburn, and other digestive problems. Other acids that are commonly used in medicine include citric acid, which is used as an antacid to neutralize stomach acid, and salicylic acid, which is used as an anti-inflammatory agent in the treatment of conditions such as acne and psoriasis. In some cases, acids can be used to treat medical conditions. For example, hydrofluoric acid is used to treat certain types of bone cancer, and lactic acid is used to treat metabolic acidosis, a condition in which the body produces too much acid. However, it is important to note that acids can also be harmful if they are not used properly. Exposure to high concentrations of acids can cause burns, corrosion of tissues, and other serious injuries. Therefore, it is important for medical professionals to use acids with caution and follow proper safety protocols.

Recombinant proteins are proteins that are produced by genetically engineering bacteria, yeast, or other organisms to express a specific gene. These proteins are typically used in medical research and drug development because they can be produced in large quantities and are often more pure and consistent than proteins that are extracted from natural sources. Recombinant proteins can be used for a variety of purposes in medicine, including as diagnostic tools, therapeutic agents, and research tools. For example, recombinant versions of human proteins such as insulin, growth hormones, and clotting factors are used to treat a variety of medical conditions. Recombinant proteins can also be used to study the function of specific genes and proteins, which can help researchers understand the underlying causes of diseases and develop new treatments.

Cerebrospinal fluid (CSF) is a clear, colorless liquid that surrounds and protects the brain and spinal cord. It is produced by the choroid plexuses, which are specialized structures located in the ventricles of the brain. CSF serves several important functions in the body, including: 1. Providing cushioning and support for the brain and spinal cord 2. Maintaining the proper pressure within the skull and spinal canal 3. Removing waste products and excess fluids from the brain and spinal cord 4. Protecting the brain and spinal cord from injury CSF is constantly being produced and absorbed by the body, and its composition and pressure can provide important clues about the health of the brain and spinal cord. In some cases, problems with the production, absorption, or circulation of CSF can lead to serious medical conditions, such as hydrocephalus or meningitis.

Glycoside hydrolases are a group of enzymes that catalyze the hydrolysis of glycosidic bonds in carbohydrates. These enzymes are involved in a wide range of biological processes, including digestion, metabolism, and signaling. In the medical field, glycoside hydrolases are often used as diagnostic tools to study carbohydrate metabolism and to develop new treatments for diseases related to carbohydrate metabolism, such as diabetes and obesity. They are also used in the production of biofuels and other industrial products.

In the medical field, "Infant, Newborn, Diseases" refers to illnesses or medical conditions that affect infants and newborns. These diseases can range from minor infections to more serious conditions that require immediate medical attention. Some common diseases that can affect infants and newborns include respiratory infections, such as pneumonia and bronchitis, gastrointestinal infections, such as diarrhea and vomiting, and infections caused by bacteria, viruses, and fungi. Other conditions that can affect infants and newborns include jaundice, congenital anomalies, and birth defects. Infants and newborns are particularly vulnerable to infections and diseases because their immune systems are not fully developed, and they may not have the same level of protection as older children and adults. As a result, it is important for healthcare providers to closely monitor infants and newborns for any signs of illness or disease and to provide prompt and appropriate medical care when necessary.

Quinolines are a class of organic compounds that have a fused ring system consisting of a six-membered aromatic ring and a five-membered heterocyclic ring containing nitrogen. They are structurally related to quinine, which is a well-known antimalarial drug. In the medical field, quinolines have been studied for their potential therapeutic applications in various diseases. Some of the most notable examples include: 1. Antimalarial activity: Quinolines have been used as antimalarial drugs for many years, with quinine being the most widely used. However, resistance to quinine has emerged in some regions, leading to the development of new quinoline-based drugs, such as chloroquine and artemisinin. 2. Antibacterial activity: Some quinolines have been found to have antibacterial activity against a range of gram-positive and gram-negative bacteria. For example, nalidixic acid is a quinoline antibiotic used to treat urinary tract infections caused by certain bacteria. 3. Antiviral activity: Quinolines have also been studied for their potential antiviral activity against viruses such as influenza, HIV, and herpes simplex virus. 4. Antifungal activity: Some quinolines have been found to have antifungal activity against Candida species, which are common causes of fungal infections in humans. Overall, quinolines have a diverse range of potential therapeutic applications in the medical field, and ongoing research is exploring their use in the treatment of various diseases.

Empyema is a medical condition characterized by the accumulation of pus in the pleural cavity, which is the space between the lungs and the chest wall. The condition is typically caused by an infection, such as pneumonia or tuberculosis, that spreads to the pleural space and causes inflammation and fluid buildup. Empyema can be classified as either primary or secondary. Primary empyema occurs when the infection originates in the pleural space, while secondary empyema occurs when the infection spreads from another part of the body, such as the lungs or the bloodstream, to the pleural space. Symptoms of empyema may include chest pain, fever, cough, and difficulty breathing. Treatment typically involves antibiotics to treat the underlying infection, as well as drainage of the fluid from the pleural space. In severe cases, surgery may be necessary to remove the infected tissue or drain the fluid.,empyema,、。

Cephalosporin resistance refers to the ability of bacteria to resist the effects of cephalosporin antibiotics, a class of drugs commonly used to treat bacterial infections. This resistance can occur due to various mechanisms, such as the production of enzymes that inactivate the antibiotic, changes in the bacterial cell wall that prevent the antibiotic from entering the cell, or mutations in the bacterial DNA that alter the target site of the antibiotic. Cephalosporin resistance is a growing concern in the medical field because it can make infections more difficult to treat and can lead to the spread of antibiotic-resistant bacteria. Infections caused by cephalosporin-resistant bacteria may require more expensive and toxic antibiotics, longer hospital stays, and increased risk of complications and death. Therefore, it is important to use cephalosporin antibiotics judiciously and to follow appropriate infection control measures to prevent the spread of antibiotic-resistant bacteria.

Gentamicins are a group of antibiotics that are commonly used to treat a wide range of bacterial infections. They are derived from the bacterium Streptomyces griseus and are classified as aminoglycosides. Gentamicins are effective against many gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. They are also effective against some gram-positive bacteria, such as Staphylococcus aureus and Enterococcus faecalis. Gentamicins are typically administered intravenously, although they can also be given intramuscularly or topically. They are often used to treat severe infections, such as sepsis, meningitis, and pneumonia. Gentamicins are also used to treat infections in the urinary tract, skin, and soft tissues. However, gentamicins can have serious side effects, including hearing loss, kidney damage, and nerve damage. They should only be used under the supervision of a healthcare professional and with careful monitoring of the patient's response to treatment.

Soft tissue infections are infections that affect the soft tissues of the body, such as the skin, muscles, tendons, ligaments, and fascia. These infections can be caused by bacteria, viruses, fungi, or other microorganisms that enter the body through cuts, wounds, or other breaks in the skin. Soft tissue infections can range from mild to severe and can affect any part of the body. Common symptoms of soft tissue infections include redness, swelling, warmth, pain, and tenderness at the site of the infection. In some cases, the infection may also cause fever, chills, and fatigue. Treatment for soft tissue infections typically involves antibiotics to kill the bacteria causing the infection. In more severe cases, surgery may be necessary to drain the infection or remove infected tissue. It is important to seek medical attention promptly if you suspect you have a soft tissue infection, as untreated infections can lead to serious complications, such as sepsis or the spread of infection to other parts of the body.

Hydrolases are a class of enzymes that catalyze the hydrolysis of various substrates, including water, to break down complex molecules into simpler ones. In the medical field, hydrolases play important roles in various physiological processes, including digestion, metabolism, and detoxification. For example, digestive enzymes such as amylase, lipase, and protease are hydrolases that break down carbohydrates, fats, and proteins, respectively, in the digestive tract. In the liver, enzymes such as alcohol dehydrogenase and cytochrome P450 are hydrolases that detoxify harmful substances such as alcohol and drugs. Hydrolases can also be used in medical treatments. For example, proteolytic enzymes such as trypsin and chymotrypsin are used in some digestive enzyme supplements to aid in the digestion of proteins. Additionally, hydrolases such as hyaluronidase are used in some medical procedures to break down connective tissue and improve tissue permeability. Overall, hydrolases are an important class of enzymes in the medical field, playing critical roles in various physiological processes and serving as potential therapeutic targets for various diseases and conditions.

In the medical field, binding sites refer to specific locations on the surface of a protein molecule where a ligand (a molecule that binds to the protein) can attach. These binding sites are often formed by a specific arrangement of amino acids within the protein, and they are critical for the protein's function. Binding sites can be found on a wide range of proteins, including enzymes, receptors, and transporters. When a ligand binds to a protein's binding site, it can cause a conformational change in the protein, which can alter its activity or function. For example, a hormone may bind to a receptor protein, triggering a signaling cascade that leads to a specific cellular response. Understanding the structure and function of binding sites is important in many areas of medicine, including drug discovery and development, as well as the study of diseases caused by mutations in proteins that affect their binding sites. By targeting specific binding sites on proteins, researchers can develop drugs that modulate protein activity and potentially treat a wide range of diseases.

In the medical field, adsorption refers to the process by which a substance adheres or sticks to the surface of another substance. This can occur when a drug or other therapeutic agent is adsorbed onto a surface, such as a medical device or a patient's skin. Adsorption can also occur when a substance is adsorbed onto the surface of a cell or tissue, which can affect its ability to interact with the body's immune system or other cells. Adsorption can be an important factor in the development and delivery of medical treatments, as it can affect the effectiveness and safety of a drug or other therapeutic agent.

Methyltransferases are a group of enzymes that transfer a methyl group (a carbon atom bonded to three hydrogen atoms) from one molecule to another. In the medical field, methyltransferases play important roles in various biological processes, including DNA methylation, RNA methylation, and protein methylation. DNA methylation is a process in which a methyl group is added to the cytosine base of DNA, which can affect gene expression. Methyltransferases that are involved in DNA methylation are called DNA methyltransferases (DNMTs). Abnormalities in DNA methylation have been linked to various diseases, including cancer, neurological disorders, and developmental disorders. RNA methylation is a process in which a methyl group is added to the ribose sugar or the nitrogenous base of RNA. Methyltransferases that are involved in RNA methylation are called RNA methyltransferases (RNMTs). RNA methylation can affect the stability, localization, and translation of RNA molecules. Protein methylation is a process in which a methyl group is added to the amino acid residues of proteins. Methyltransferases that are involved in protein methylation are called protein methyltransferases (PMTs). Protein methylation can affect protein-protein interactions, protein stability, and protein function. Overall, methyltransferases play important roles in regulating gene expression, RNA stability, and protein function, and their dysfunction can contribute to the development of various diseases.

Lincosamides are a class of antibiotics that are used to treat bacterial infections. They are similar in structure to the macrolides, but have a different mechanism of action. Lincosamides work by inhibiting the growth of bacteria by interfering with the synthesis of a protein called peptidoglycan, which is a key component of bacterial cell walls. This leads to the death of the bacteria. Lincosamides are commonly used to treat infections of the respiratory tract, skin, and soft tissues. They are also used to treat certain types of bacterial infections in animals, such as mastitis in cows and salmonellosis in poultry. Examples of lincosamides include lincomycin and clindamycin. These antibiotics are available in both oral and injectable forms, and are usually given for a period of several days to several weeks, depending on the severity of the infection and the specific antibiotic being used.

Beta-Lactams are a class of antibiotics that are derived from the beta-lactam ring structure. They are one of the most widely used classes of antibiotics and are effective against a broad range of bacterial infections. The beta-lactam ring is a six-membered ring with a beta-hydroxy group and an amide group. The beta-lactam antibiotics work by inhibiting the synthesis of the bacterial cell wall, which leads to cell lysis and death. There are several subclasses of beta-lactam antibiotics, including penicillins, cephalosporins, monobactams, and carbapenems. Each subclass has its own unique properties and is effective against different types of bacteria. Beta-lactam antibiotics are often used to treat a variety of bacterial infections, including pneumonia, urinary tract infections, skin infections, and infections of the respiratory, gastrointestinal, and genitourinary tracts. They are generally well-tolerated and have a low risk of side effects, although allergic reactions can occur in some people.

Polysaccharides are complex carbohydrates that are composed of long chains of monosaccharide units linked together by glycosidic bonds. They are found in many different types of biological materials, including plant cell walls, animal tissues, and microorganisms. In the medical field, polysaccharides are often used as drugs or therapeutic agents, due to their ability to modulate immune responses, promote wound healing, and provide other beneficial effects. Some examples of polysaccharides that are used in medicine include hyaluronic acid, chondroitin sulfate, heparin, and dextran.

Group B strep (GBS) disease can be prevented in newborns, but its not clear how to prevent this disease in others. ... There are currently no vaccines to prevent group B strep (GBS) disease but they are under development. There are things doctors ...
Pneumococcal disease is caused by bacteria called Streptococcus pneumoniae (pneumococcus). People with pneumococcal disease can ...
Available Streptococcus specimens isolated from a brain abscess, epidural empyema, subdural empyema, blood, or cerebrospinal ... Pediatric Brain Abscesses, Epidural Empyemas, and Subdural Empyemas Associated With Streptococcus Species. United States, ... and unspecified streptococci (three).. ¶¶Orbital abscess (two), forehead abscess (one), middle meatus (one), ear aspirate (two ... are often caused by Streptococcus species but might also be polymicrobial or caused by other genera, such as Staphylococcus. On ...
Group B streptococcus (GBS) is a type of bacteria that some women carry in their intestines and vagina. It is not passed ... Note: Strep throat is caused by a different bacterium. If you have had strep throat, or got it while you were pregnant, it does ... Group B streptococcus (GBS) is a type of bacteria that some women carry in their intestines and vagina. It is not passed ...
Pneumococcal infections are caused by Streptococcus pneumoniae, a gram-positive, catalase-negative organism commonly referred ... encoded search term (Pneumococcal Infections (Streptococcus pneumoniae)) and Pneumococcal Infections (Streptococcus pneumoniae) ... Pneumococcal Infections (Streptococcus pneumoniae). Updated: Jun 08, 2023 * Author: Urvya Iyer, MD, MPH; Chief Editor: John L ... Streptococcus pneumoniae: virulence factors and variation. Clin Microbiol Infect. 2010 May. 16(5):411-8. [QxMD MEDLINE Link]. ...
Drug-resistant Streptococcus pneumoniae -- Kentucky and Tennessee, 1993. MMWR 1994;43:23-5,31. *Butler JC, Breiman RF, Facklam ... Streptococcus pneumoniae is an important cause of community-acquired bacterial pneumonia, meningitis, acute otitis media, and ... Antimicrobial resistance of Streptococcus pneumoniae in the United States, 1979-1987. J Infect Dis 1991;163:1273-8. * ... Dagan R, Yagupsky P, Wasas A, Klugman K. Penicillin-resistant Streptococcus pneumoniae (PenRSP): an increasing problem in ...
Streptococcus thermophilus formerly known as Streptococcus salivarius subsp. thermophilus[2][1] is a gram-positive bacterium, ... "Streptococcus." Encyclopædia Britannica. Encyclopædia Britannica Online. 13 April 2011. *^ "Thermophile." Encyclopædia ... Hutkins, Robert (2002). "Streptococcus Thermophilus LMD-9". JGI Microbes.. *^ Taylor, John R. and Mitchell, Deborah. The Wonder ... The genus Streptococcus includes several pathogenic species, such as S. pneumoniae and S. pyogenes, but food industries ...
Surveillance for Penicillin-Nonsusceptible Streptococcus pneumoniae -- New York City, 1995 Streptococcus pneumoniae has become ... Defining the public health impact of drug-resistant Streptococcus pneumoniae: report of a working group. MMWR 1996;45(no. RR-1 ... Bacteremia with Streptococcus pneumoniae: implications for therapy and prevention. JAMA 1996;275:194-8. ...
Strep throat is a common cause of sore throat in kids and teens. It usually requires treatment with antibiotics, but improves ... What Is Strep Throat?. Strep throat is an infection caused by a type of bacteria called group A strep (GAS). These bacteria are ... Can Strep Throat Be Prevented?. There is no vaccine to protect against strep throat, and getting strep throat once doesnt ... Is Strep Throat Contagious?. Strep throat is very contagious. Anybody can get it, but most cases are in school-age kids and ...
... researchers in France argue that the bacteria Streptococcus thermophilus, used in making yogurt and cheese, has building ... Related tags Streptococcus Milk Bacteria In a new review of existing studies, researchers in France argue that the bacteria ... S. thermophilus ​is the only Streptococcus ​species to have a Generally Recognized as Safe (GRAS) no-objections letter from ... Streptococcus thermophilus, used in making yogurt and cheese, has building evidence supporting its probiotic status. ...
For highly sensitive and specific detection of Strep-tagged proteins ... Strep-tag Antibody. Strep-tag Antibody. For highly sensitive and specific detection of Strep-tagged proteins. ... Strep-Tactin SuperFlow or Strep-Tactin Magnetic Beads). Protein is eluted from the Strep-Tactin matrix using either biotin or ... Monoclonal mouse Strep-tag antibodies are used to detect recombinant proteins carrying the short Strep-tag affinity tag epitope ...
bulgaricus and Streptococcus thermophilus). This standard was last reviewed and confirmed in 2020. Therefore this version ...
Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life- ... Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life- ... Strep genes linked to flesh-eating bacterial infections. September 23, 2017. ScienceBlog.com ... "Like group A Streptococcus, many pathogenic bacteria have completely sequenced genomes, but we dont know what most of the ...
Will look for streptococcus OR agalactiae and will list results of streptococcus AND agalactiae first. +streptococcus + ... Streptococcus pneumoniae. E.Berntsson, PHLS, Göteborg, Sweden. 1979-06-01. 35180. Streptococcus pneumoniae. Human blood. ... streptococcus +aga* -sweden. Will match records that have streptococcus, part of a word that starts with aga and does not have ... "streptococcus agalactiae". Will match records that have the words streptococcus agalactiae. before:2012-00-00. Will match ...
... Sep 12, 2022. Ashley Gallagher, ... The FDA announced breakthrough therapy designation for Group B Streptococcus (GBS) vaccine candidate, GBS6 (PF-06760805; Pfizer ... FDA grants breakthrough therapy designation to Pfizers group B Streptococcus vaccine candidate to help prevent infection in ...
Streptococcus agalactiae NEM316). Find diseases associated with this biological target and compounds tested against it in ...
Group B Strep (GBS), also known as Streptococcus agalactiae, is a Gram-positive, beta-hemolytic, catalase-negative, facultative ... Streptococcus agalactiae (group B Streptococcus) bacteria. Photo Credit: Alissa Eckert, who is a medical illustrator at the CDC ... Group B Strep and Pregnancy. From MicrobeWiki, the student-edited microbiology resource ... factor for an early-onset GBS infection in a neonate is colonization of a birthing persons genital tract with Group B strep ...
What Is Strep Throat?. Before we dive into when the pain will end, lets understand what causes it in the first place. Strep ... Can Strep Throat Come Back?. YES!! Dont get too excited yet - repeating strep infections occur frequently unless treated ... Strep throat is an unpleasant experience - no two ways about it. But with the right approach towards managing symptoms ... If youve ever had strep throat, you know how painful it can be. Swallowing feels like a chore and talking is just plain ...
Received as Streptococcus mutans. Show Phenotypic Features In LAX Phenotypic features in LAX. Api RID32S: 111 111 151 551 551 ...
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Streptococcus pneumoniae presents a particularly acute problem in this respect, as it is capable of rapid evolution by ... Streptococcus pneumoniae presents a particularly acute problem in this respect, as it is capable of rapid evolution by ... In vitro reconstitution of peptidoglycan assembly from the Gram-positive pathogen Streptococcus pneumoniae ACS Chem Biol. 2013 ... including streptococci, staphylococci, or enterococci pathogens. We report here for the first time the in vitro assembly of ...
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... Frequency In Adults - Remove Tonsils?. 1 Comment I have strep throat again. I usually get it once or twice a year ... Im Sick with Strep Throat. Leave a Comment Well, I figured since my son had it I would probably get it and today the doctor ... Son has Strep Throat. Leave a Comment On Wednesday, my son took a nap - he NEVER takes a nap. I kind of figured something was ... He had strep throat back at the beginning of April and I didnt get it at that time, which totally surprised me and I was ...
Learn about the veterinary topic of Streptococcus dysgalactiae equisimilis Infection in Pigs. Find specific details on this ... they are considered the most important beta-hemolytic streptococci involved in lesions in pigs. These streptococci are common ... Streptococcus dysgalactiae equisimilis Infection in Pigs By Marcelo Gottschalk , DVM, PhD, Department of Pathology and ... Beta-hemolytic streptococci are sensitive to beta-lactam antibiotics. Long-acting antibacterial agents may be beneficial, and ...
... for the antibiotics used to treat strep A, after a surge in cases and the deaths of at least 19 children throughout the UK. ... The Scottish Government has issued a supply alert notice for the antibiotics used to treat strep A, after a surge in cases ... The Scottish Government has issued a supply alert notice for the antibiotics used to treat strep A, after a surge in cases ... Now pharmacists have been warned the syrup versions of the antibiotics used to treat strep A in children are "temporarily in ...
Now, doctors are warning about a bacterial infection called group A strep. ... Strep A cases different from strep throat infections. The Colorado Department of Public Health and Environment said there have ... Doctors say group A strep is more rare than other respiratory illnesses, but it could make your little one really sick if they ... "There has been a national shortage of amoxicillin, one of the antibiotics that is commonly used to treat strep throat, but ...
Antibiotics could be given to children at schools affected by Strep A to stop the spread of the infection, schools minister ... Antibiotics could be given to children at schools affected by Strep A to stop the spread of the infection, schools minister ... Antibiotics could be given to children at schools affected by Strep A infections, schools minister Nick Gibb says. ...
  • Pneumococcal disease is caused by bacteria called Streptococcus pneumoniae (pneumococcus). (cdc.gov)
  • Streptococcus pneumoniae is a major pathogen of humans, causing diseases such as pneumonia and meningitis. (nih.gov)
  • The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. (nih.gov)
  • Regions of Diversity 8, 9 and 13 contribute to Streptococcus pneumoniae virulence. (nih.gov)
  • The transforming Streptococcus pneumoniae in the 21st century. (nih.gov)
  • Bacterial pathogens commonly implicated in community-acquired RTIs include Streptococcus pneumoniae , Haemophilus influenzae , Moraxella catarrhalis , and Streptococcus pyogenes . (medscape.com)
  • Effects of new penicillin susceptibility breakpoints for Streptococcus pneumoniae- United States, 2006-2007. (medscape.com)
  • Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. (medscape.com)
  • Streptococcus pneumoniae. (medscape.com)
  • Serotype 19A is the Most Common Streptococcus pneumoniae Isolate in Children With Chronic Sinusitis. (medscape.com)
  • Recommendations for the Prevention of Streptococcus pneumoniae Infections in Infants and Children: Use of 13-Valent Pneumococcal Conjugate Vaccine (PCV13) and Pneumococcal Polysaccharide Vaccine (PPSV23). (medscape.com)
  • Streptococcus pneumoniae is an important cause of community-acquired bacterial pneumonia, meningitis, acute otitis media, and other infections (1). (cdc.gov)
  • CDC's Streptococcus Laboratory provides support for active population-based surveillance for invasive streptococcal disease, primarily caused by groups A and B streptococci and Streptococcus pneumoniae . (cdc.gov)
  • We report a case of Streptococcus pneumoniae and COVID-19 coinfection in a previously healthy 4-year-old child. (hindawi.com)
  • Here, we report a previously healthy and vaccinated child with COVID-19 and Streptococcus pneumoniae bacterial coinfection. (hindawi.com)
  • Respiratory viruses might influence Streptococcus pneumoniae nasal carriage and subsequent disease risk. (frontiersin.org)
  • A streptococcus (GAS) throat culture, rapid strep test, streptococcus pyogenes What is it used for? (nih.gov)
  • Strep throat is caused by a bacte​rium called Streptococcus pyogenes or group A Streptococcus . (healthychildren.org)
  • Streptococcus pyogenes falls into the latter category. (ucsd.edu)
  • An effective vaccine will prevent not only strep throat and impetigo but also more serious invasive disease and post-infectious complications like rheumatic fever. (nih.gov)
  • Group A strep organisms can cause skin infections such as impetigo (itchy, red, oozing sores) and cellulitis (red, swollen, painful skin). (healthychildren.org)
  • The common non-invasive illnesses include strep throat, skin infections, such as impetigo, and scarlet fever. (cp24.com)
  • Infections cause by Strep A include the skin infection impetigo, scarlet fever and strep throat. (shropshirestar.com)
  • What infections does group A strep cause? (healthychildren.org)
  • Rarely, group A strep can cause serious infections that require immediate medical attention and even intensive care. (healthychildren.org)
  • It's important to be able to distinguish a strep throat from a viral sore throat, because strep infections are treated with antibiotics. (healthychildren.org)
  • Untreated strep infections also can lead to rheumatic fever, a disease that affects the heart. (healthychildren.org)
  • The purpose of this Funding Opportunity Announcement (FOA) is to support discovery and design of novel Group A Streptococcus (GAS) vaccine candidates and their advancement into preclinical evaluation for broad protection against GAS infections. (nih.gov)
  • Scotland's health secretary said the country's health service is 'adequately able' to deal with Strep A infections. (shropshirestar.com)
  • Scotland's health secretary Humza Yousaf has said the country's health service is "adequately able" to deal with Strep A infections despite warnings that cases are expected to increase. (shropshirestar.com)
  • These simple actions can help to reduce the spread of common infections like Group A strep. (shropshirestar.com)
  • Both Sharon Jones, whose son, plaintiff Corey Jones, lives in Parker, and Jesus Marquez died of strep infections that could have been treated with simple antibiotics. (prisonlegalnews.org)
  • Group A Streptococcus bacteria can cause strep throat and infections in skin and soft tissue. (medscape.com)
  • Invasive strep A infections initially decreased during the COVID-19 pandemic amid measures to reduce the spread of disease, such as masking and social distancing. (medscape.com)
  • Cite this: CDC Reports Uptick in Invasive Strep A Infections - Medscape - Sep 14, 2022. (medscape.com)
  • We hope this research will be useful going forward in designing drug therapies that combat the growing number of strep A infections worldwide. (ucsd.edu)
  • Although there are antibiotics that treat strep A infections, there are no vaccines to prevent infections. (ucsd.edu)
  • We don't have exact numbers of cases because the Centers for Disease Control and Prevention doesn't actually track run-of-the-mill strep infections, but strep activity is higher these days. (usf.edu)
  • Regardless of what kind of strep someone has, though, strep infections need to be treated with antibiotics. (usf.edu)
  • There have been 13 reports of invasive Strep A in children aged under 10 in Scotland since the start of October, according to latest data. (shropshirestar.com)
  • LUPKIN: Now, the CDC does track a certain kind of strep called invasive group A strep. (usf.edu)
  • Invasive strep means instead of the bacteria staying in the throat, it goes to other parts of the body, so it can get in the bloodstream and cause a rash. (usf.edu)
  • Antibiotics can help people with strep throat feel better faster and prevent spreading it to others. (cdc.gov)
  • Skin infection caused by group A strep may be treated with antibiotic ointment, or sometimes with oral or IV antibiotics. (healthychildren.org)
  • When antibiotics are given to treat the most common group A strep infection, most children improve within a few days. (healthychildren.org)
  • If a child's strep throat is not treated with antibiotics, or if they don't complete the treatment, the infection may worsen or spread to other parts of their body. (healthychildren.org)
  • However, strep throat is an infection in the throat and tonsils caused by bacteria called group A Streptococcus (group A strep). (cdc.gov)
  • Group B streptococcus (GBS) is a type of bacteria that some women carry in their intestines and vagina. (medlineplus.gov)
  • Strep throat is an infection caused by a specific type of bacteria, Streptococcus . (healthychildren.org)
  • The laboratory is a reference center for the identification and characterization of streptococci and other Gram-positive catalase-negative cocci. (cdc.gov)
  • Group A strep bacteria are very contagious. (cdc.gov)
  • People who are sick with strep throat are more contagious than those who do not have symptoms. (cdc.gov)
  • Group A strep bacteria can be extremely contagious. (healthychildren.org)
  • Is strep throat and other types of throat infection contagious? (healthychildren.org)
  • Strep throat is very contagious. (health.gov.fj)
  • The primary treatment for sore throats caused by Group A Strep is penicillin, an antibiotic that's taken orally. (healthychildren.org)
  • Forty-three (43) pattern of group A streptococci in our strains of group A streptococci isolated country the present study was conducted from the patients were serotyped by stan- to determine the presence of group A strep- dard methods [ 13 ] at the Institut Für Ex- tococci in acute pharyngitis cases and in perimentelle Mikrobiologie, Jena, Germany. (who.int)
  • This means it may be possible to create a vaccine that could be effective against multiple strains of group A strep, moving the world one step closer to treating a pervasive disease. (ucsd.edu)
  • Strep throat, the bacterial infection that typically causes a sore throat, seems to be everywhere these days. (usf.edu)
  • To assess the number of Streptococcus mutans in saliva of patients with denture stomatitis before and after antifungal therapy. (bvsalud.org)
  • The 16S rRNA gene sequence for all the seven samples had no sequence variation between the isolates and gave a 100% similarity to plus, plus strand with Streptococcus agalactiae strain A909 Accession number NC_007432.1 and S. agalactiae strain H36B (Accession number AAJS01000007). (scialert.net)
  • While some scientists are conducting animal model studies to obtain data to pursue clinical trials in humans, other scientists are close to evaluating group A streptococcus vaccine candidates in Phase I clinical trials. (nih.gov)
  • Group A Strep (GAS) is an infection caused by bacteria that spreads from person-to-person through direct contact with the nose, throat, respiratory droplets or wound secretions. (cp24.com)
  • If they think you might have strep throat, they will swab your throat to test for strep throat. (cdc.gov)
  • A rapid strep test involves swabbing the throat and running a test on the swab. (cdc.gov)
  • If the test is negative , but a doctor still suspects strep throat, then the doctor can take a throat culture swab. (cdc.gov)
  • If your child has a sore throat and fever without symptoms of viral infection, your health care provider may swab your child's throat to test for Group A Strep infection. (healthychildren.org)
  • Did they do a throat swab for strep? (conductdisorders.com)
  • The changing epidemiology of group A the Microbiology Laboratory of Farhat streptococci and rheumatic fever is said to Hached Hospital as soon as possible (2 to 3 be related to changes in the distribution of hours after sampling). (who.int)
  • Strep Throat, Sore Throat or Tonsillitis: What's the Difference? (healthychildren.org)
  • The terms sore throat, strep throat, and tonsillitis often are used interchangeably, but they don't mean the same thing. (healthychildren.org)
  • Cough, runny nose, hoarseness (changes in your voices that make sound raspy) and conjunctivitis (also called pinkeye) are not symptoms of strep throat. (healthychildren.org)
  • The most common group A strep infection is strep throat , which usually causes fever and sore throat without viral illness symptoms such as runny nose and cough. (healthychildren.org)
  • ABSTRACT A 1-year prospective study in 2 paediatric outpatient clinics in Sousse, Tunisia, aimed to determine the presence of group A streptococci in acute pharyngitis cases and carriers, and the distribution of the serotypes and biotypes. (who.int)
  • Many predictive rules have been developed to guide the management of suspected Group A Strep Pharyngitis. (medscape.com)
  • The worst sore throat I've ever had was viral and not strep. (conductdisorders.com)
  • SRL, I'd head back to the doctor tomorrow for a throat culture, which as you well know, is the ONLY way to distinguish viral from strep throat. (conductdisorders.com)
  • Group B streptococci generally cause such diseases as neonatal meningitis and sepsis. (innvista.com)
  • Thus, it is important to All swabs were inoculated onto 5% establish the epidemiological patterns of horse blood agar plates, with nalidixic acid group A streptococci in different countries and colistin and incubated in a CO -en- and regions, and especially to serotype the 2 riched atmosphere for 24 hours at 37 °C. strains that have been isolated. (who.int)
  • The Infectious Diseases Society of America recommendation remains that if Group A Streptococcus is suspected, that laboratory tests (Rapid Antigen Detection Testing or throat Culture) be used to support the diagnosis. (medscape.com)
  • Rarely, people can spread group A strep bacteria through food that is not handled properly (visit CDC's food safety page ). (cdc.gov)
  • It usually takes two to five days for someone exposed to group A strep bacteria to become ill with strep throat. (cdc.gov)
  • Group A strep bacteria often live in the nose and throat. (cdc.gov)
  • People can also spread group A strep bacteria from infected sores on their skin. (cdc.gov)
  • Some people infected with group A strep do not have symptoms or seem sick. (cdc.gov)
  • Crowded settings can increase the risk of getting a group A strep infection. (cdc.gov)
  • The test quickly shows if group A strep bacteria are causing the illness. (cdc.gov)
  • NIAID supports research to develop a group A streptococcus vaccine, and several candidate vaccines are in various phases of development. (nih.gov)
  • As a result of NIAID-supported research, the first group A streptococcus vaccine clinical trial in 30 years was started. (nih.gov)
  • If your child has ever had a throat or skin infection, it may have been caused by group A streptococcal (Group A Strep) bacteria. (healthychildren.org)
  • How long is the incubation period for group A strep? (healthychildren.org)
  • How is group A strep diagnosed in children? (healthychildren.org)
  • How is a group A strep infection treated? (healthychildren.org)
  • How long should my child stay home with a group A strep infection? (healthychildren.org)
  • If your child has a throat or skin infection caused by group A strep bacteria, they can go back to school or child care once they've had two doses of a course of an appropriate antibiotic 12 hours apart without fever. (healthychildren.org)
  • How long does it take to recover from group A strep infection? (healthychildren.org)
  • Group A Streptococcus (GAS), a Gram-positive bacterium, is one of the top infectious disease causes of death and disability worldwide, with an estimated number of annual deaths exceeding 500,000, mostly in low and middle income countries. (nih.gov)
  • Group A streptococci: Submit emm gene sequence to determine emm subtype of your strain. (cdc.gov)
  • Group A Strep infection is the cause of the previously known "childbed fever," where the bacteria spread rapidly from the inflammed uterus into the blood. (innvista.com)
  • After surgery, however, the wounds can leak nutrients, and massive amounts of nutrients are needed to replace what group A strep destroys. (innvista.com)
  • To learn more about How to Help Protect Your Baby from Group B Strep (GBS) , click HERE . (groupbstrepinternational.org)
  • The vast number of different strains is one reason why it is hard to acquire any immunity against group A strep, and one person can be infected over and over again. (ucsd.edu)
  • When your child has a strep throat, the tonsils are usually very inflamed, and the inflammation may affect the surrounding part of the throat as well. (healthychildren.org)
  • Children over three years of age with strep may have an extremely painful throat, fever over 102 ​degrees Fahrenheit (38.9 degrees Celsius), swollen glands in the neck and pus on the tonsils. (healthychildren.org)
  • There are two types of tests for strep throat: a rapid strep test and throat culture. (cdc.gov)
  • If the rapid strep test is negative, your doctor may confirm the result with a throat culture (see below). (healthychildren.org)
  • It is usually caused by staphylococcal (staph) bacteria, but it can also be caused by streptococcal (strep) bacteria. (nih.gov)
  • Some pediatricians' offices have quick-result strep tests that can help diagnose streptococcal infection in several minutes. (healthychildren.org)
  • Most pediatric offices perform rapid strep tests that provide findings within minutes. (healthychildren.org)
  • The Pediatric Strep Score calculator is created by QxMD. (medscape.com)
  • Strep A bacteria are commonly found in the throat and on the skin, and some people have no symptoms. (shropshirestar.com)
  • Prior to March 2015, he developed strep throat, and on the 2nd and 3rd of the month, medical staffers were repeatedly informed about the seriousness of his symptoms, including chest pains. (prisonlegalnews.org)
  • Strep throat is especially common among school-aged children and teenagers. (healthychildren.org)
  • But it is a very treatable illness and therefore I don't have any concerns about the ability of the health service to treat Strep A. (shropshirestar.com)
  • Unless it's dosed differently (as in higher) from how it's prescribed to treat a bronchial infection, I believe Zithromax will only partially treat a strep infection. (conductdisorders.com)
  • They also should obtain cultures for suspected cases of iGAS as clinically indicated, follow guidelines for the diagnosis and treatment of strep throat, and be aware of alternative ways to treat strep throat in children amid a shortage of amoxicillin suspension . (medscape.com)
  • Further solidifying its leadership position, Burst has also secured a crucial NIH grant, ensuring accelerated development and commercialization of their cutting-edge rapid strep test technology platform. (wpri.com)
  • Strep throat is more common in children than adults. (cdc.gov)
  • Strep throat is most common among school-age children and adolescents, peaking at 7 or 8 years of age. (healthychildren.org)
  • However, none of the rules have 100% Sensitivities and thus the Strep Score should only be used as a tool to assist in determining which children may require throat swabs. (medscape.com)
  • Indeed, Marquez was felled by complications from strep throat - the sort of malady that strikes many children multiple times during their formative years without significant repercussions. (prisonlegalnews.org)
  • And after two years of record low cases of this kind of strep during the height of the pandemic, those cases are actually higher than usual this season. (usf.edu)
  • Anyone can get strep throat, but there are some factors that can increase the risk of getting this common infection. (cdc.gov)
  • Close contact with another person with strep throat is the most common risk factor for illness. (cdc.gov)
  • CAITLIN RIVERS: This whole winter season has been really tough for the common pathogens that keep us out of school and out of work, and strep throat is one that has really been going around. (usf.edu)
  • If the test shows that your child does have strep throat, your pediatrician will prescribe an antibiotic to be taken by mouth or by injection (a shot). (healthychildren.org)
  • When difficult child has strep - and she gets it a lot - her throat only hurts for a couple of hours. (conductdisorders.com)
  • How Can I Prevent My Child from Getting Strep Throat? (health.gov.fj)
  • Doctors can do a quick test to see if a sore throat is strep throat. (cdc.gov)
  • Heck, she even doubted whether I had a cold at all so she sure wasn't going to offer a strep test. (conductdisorders.com)
  • by the way, the second time I went to the dr., the strep test was negative, but it turned out I did have it again. (conductdisorders.com)
  • I'd go back to doctor and request a strep test. (conductdisorders.com)
  • So a shortage of amoxicillin is making things really tricky for families, and that actually hit home for Caitlin Rivers late last year when both of her kids had strep. (usf.edu)
  • In general, strep throat is a mild disease, but it can be very painful. (cdc.gov)
  • LL-37 is produced on the skin and kills bacteria by puncturing their cell membrane - similar to a needle popping a balloon - but some strep bacteria are able to capture LL-37 and prevent it from working. (ucsd.edu)