Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
Raw and processed or manufactured milk and milk-derived products. These are usually from cows (bovine) but are also from goats, sheep, reindeer, and water buffalo.
The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)
Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
The rate dynamics in chemical or physical systems.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
A class of compounds composed of repeating 5-carbon units of HEMITERPENES.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Articles of food which are derived by a process of manufacture from any portion of carcasses of any animal used for food (e.g., head cheese, sausage, scrapple).
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Use of written, printed, or graphic materials upon or accompanying a product or its container or wrapper. It includes purpose, effect, description, directions, hazards, warnings, and other relevant information.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Established cell cultures that have the potential to propagate indefinitely.
Cation-transporting proteins that utilize the energy of ATP hydrolysis for the transport of CALCIUM. They differ from CALCIUM CHANNELS which allow calcium to pass through a membrane without the use of energy.
A fluorescent calcium chelating agent which is used to study intracellular calcium in tissues.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Elements of limited time intervals, contributing to particular results or situations.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.
The functional hereditary units of BACTERIA.
Proteins found in any species of bacterium.
Substances or materials used in the course of housekeeping or personal routine.
The production and movement of food items from point of origin to use or consumption.
Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
The fluid inside CELLS.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
A divalent calcium ionophore that is widely used as a tool to investigate the role of intracellular calcium in cellular processes.
Intracellular fluid from the cytoplasm after removal of ORGANELLES and other insoluble cytoplasmic components.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
The sum of the weight of all the atoms in a molecule.
Proteins prepared by recombinant DNA technology.
Inorganic or organic compounds that contain boron as an integral part of the molecule.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Food products manufactured from poultry.
The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
The industry concerned with processing, preparing, preserving, distributing, and serving of foods and beverages.
Activity involved in transfer of goods from producer to consumer or in the exchange of services.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
The process of cleaving a chemical compound by the addition of a molecule of water.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Substances and products derived from NICOTIANA TABACUM.
Use of restriction endonucleases to analyze and generate a physical map of genomes, genes, or other segments of DNA.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
Proteins found in any species of virus.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Organic compounds containing a carbonyl group in the form -CHO.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Unsaturated derivatives of the ESTRANES with methyl groups at carbon-13, with no carbon at carbon-10, and with no more than one carbon at carbon-17. They must contain one or more double bonds.
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC, it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.
Laws concerned with manufacturing, dispensing, and marketing of drugs.
A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
A group of compounds that are derivatives of oxo-pyrrolidines. A member of this group is 2-oxo pyrrolidine, which is an intermediate in the manufacture of polyvinylpyrrolidone. (From Merck Index, 11th ed)
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Calcium-transporting ATPases that catalyze the active transport of CALCIUM into the SARCOPLASMIC RETICULUM vesicles from the CYTOPLASM. They are primarily found in MUSCLE CELLS and play a role in the relaxation of MUSCLES.
Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Transport proteins that carry specific substances in the blood or across cell membranes.
A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Lanthanum. The prototypical element in the rare earth family of metals. It has the atomic symbol La, atomic number 57, and atomic weight 138.91. Lanthanide ion is used in experimental biology as a calcium antagonist; lanthanum oxide improves the optical properties of glass.
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Regular course of eating and drinking adopted by a person or animal.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Unstable isotopes of calcium that decay or disintegrate emitting radiation. Ca atoms with atomic weights 39, 41, 45, 47, 49, and 50 are radioactive calcium isotopes.
The act or practice of calling public attention to a product, service, need, etc., especially by paid announcements in newspapers, magazines, on radio, or on television. (Random House Unabridged Dictionary, 2d ed)
The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Phosphoric acid esters of inositol. They include mono- and polyphosphoric acid esters, with the exception of inositol hexaphosphate which is PHYTIC ACID.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
The movement of ions across energy-transducing cell membranes. Transport can be active, passive or facilitated. Ions may travel by themselves (uniport), or as a group of two or more ions in the same (symport) or opposite (antiport) directions.
Medicines that can be sold legally without a DRUG PRESCRIPTION.
The functional hereditary units of VIRUSES.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.
Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
The processes whereby the internal environment of an organism tends to remain balanced and stable.
Food products manufactured from fish (e.g., FISH FLOUR, fish meal).
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Thin structures that encapsulate subcellular structures or ORGANELLES in EUKARYOTIC CELLS. They include a variety of membranes associated with the CELL NUCLEUS; the MITOCHONDRIA; the GOLGI APPARATUS; the ENDOPLASMIC RETICULUM; LYSOSOMES; PLASTIDS; and VACUOLES.
Prepared food that is ready to eat or partially prepared food that has a final preparation time of a few minutes or less.
Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.
A non-medical term defined by the lay public as a food that has little or no preservatives, which has not undergone major processing, enrichment or refinement and which may be grown without pesticides. (from Segen, The Dictionary of Modern Medicine, 1992)
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
A network of tubules and sacs in the cytoplasm of SKELETAL MUSCLE FIBERS that assist with muscle contraction and relaxation by releasing and storing calcium ions.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
The relationships of groups of organisms as reflected by their genetic makeup.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Any method used for determining the location of and relative distances between genes on a chromosome.
A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.
A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
An imidazole derivative that is commonly used as a topical antifungal agent.
Deoxyribonucleic acid that makes up the genetic material of viruses.
The chemical reactions involved in the production and utilization of various forms of energy in cells.
Any substances taken in by the body that provide nourishment.
A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166)
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Form in which product is processed or wrapped and labeled. PRODUCT LABELING is also available.
The aggregate business enterprise of agriculture, manufacture, and distribution related to tobacco and tobacco-derived products.
Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
The functional hereditary units of FUNGI.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.
Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
An ethylmercury-sulfidobenzoate that has been used as a preservative in VACCINES; ANTIVENINS; and OINTMENTS. It was formerly used as a topical antiseptic. It degrades to ethylmercury and thiosalicylate.
A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.
Proteins found in any species of fungus.
The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
An enzyme of the oxidoreductase class primarily found in PLANTS. It catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
The presence of organisms, or any foreign material that makes a drug preparation impure.
Interstitial space between cells, occupied by INTERSTITIAL FLUID as well as amorphous and fibrous substances. For organisms with a CELL WALL, the extracellular space includes everything outside of the CELL MEMBRANE including the PERIPLASM and the cell wall.
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.
"The Product". iTunes Store. Apple Inc. Retrieved 4 November 2015. "Cult of Fake". iTunes Store. Apple Inc. Retrieved 22 October ... "Black Dog Bite". iTunes Store. Apple Inc. Retrieved 22 October 2017. "The Ignorance Cartel". iTunes Store. Apple Inc. Retrieved ... "Krankhaus: Surgically Atoned". iTunes Store. Apple Inc. Retrieved 1 November 2015. "Black Kingdom Red Kingdom". iTunes Store. ... "I Know (Halloween Mix) - Single". iTunes Store. Apple Inc. Retrieved 4 November 2015. "Vena Cava by Angelspit (Official)". ...
"Without Me Limited Edition 7" Vinyl + Digital Singles - HALSEY OFFICIAL STORE". Halsey Official Store. Archived from the ... The video features product placement by Beats and YSL. Digital download and streaming "Without Me" - 3:21 Digital download and ... "Without Me - Single by Halsey on iTunes". iTunes Store. Apple Inc. October 4, 2018. Archived from the original on October 6, ... "Without Me - Single by Halsey on iTunes". iTunes Store. Apple Inc. October 4, 2018. Archived from the original on October 6, ...
"Product Category - Journals , EnlightenNext Store". Retrieved 2012-08-31. Bruce Sterling, "The Last Viridian ...
"Maple Product History". Retrieved 2020-03-20. "Maplesoft Web Store". Retrieved 2019-03-14. "PTC Web Store". Retrieved 2015-02- ... "LiveMath Store". Retrieved 2020-02-25. MacCallum, Malcolm A. H. (2018). "Computer algebra in gravity research". Living Reviews ... "Wolfram Worldwide Web Store". Retrieved 2008-11-20. Kastrenakes, Jacob (2013-11-21). "Raspberry Pi now includes Mathematica and ...
... redesigning stores for visual appeal, and marketing PETsMART as a one-stop shop for pet products and services. By 2002 the ... In 1998 PETsMART opened its 500th store, and by year's end had 423 stores in the U.S., 93 stores in the UK, and 18 in Canada. ... Three employees of the Nashville store - the store manager, assistant store manager, and customer engagement manager - pleaded ... In 2001 the company laid out a three-year plan to expand in-store services and products and provide high-quality customer ...
"Canon EOS 7D Mark II Body". Canon Online Store. BH listing. "Canon 7D Mark II EOS DSLR Camera (Canon 7D ... Product Page. ...
"Cleopatra Records : Store , Product Categories Archive , Record Label". 2013-10-17. Retrieved 2015-03-28. " ...
"Product info" (PDF). "Product info" (PDF). "product info" (PDF). ... "Honor 6X Smartphone". Huawei Nova "小米Max 2 - 小米商城". "Xiaomi official website". "Xiaomi Mi ... "Product info" (PDF). "Product info" (PDF). "Product info" (PDF). ... "Product info" (PDF). "Product info" (PDF). "Product info" (PDF). ...
"Modules". Modelio modules store. Retrieved 2020-12-31. "Find source code". Modelio Open Source. Retrieved 2020-08-29. "Product ... ". "Product History". Retrieved 2013-09-05. "Diagram CASE Tool for Software Modeling & Analysis - UML, BPMN, ERD". www. ...
"TBS Product Stewardship". The Beer Store. Archived from the original on 2010-02-19. Retrieved 2010-04-06. Although a ... The program was promoted via in-store advertising at the LCBO and its Agency Stores, at The Beer Store and its Retail Partners ... LCBO Agency Stores and The Beer Store Retail Partners, and Ontario winery and distillery stores. Approximately "360 million ... Bottles must be returned to Beer Store locations to get the deposit back. The Beer Store will be paid 10 cents per container to ...
Product Page: Still Standing. iTunes Store Netherlands. retrieved on 2010-03-21. Product Page: Still Standing. ... Product Page: Still Standing. Retrieved on 2010-03-23. Product Page: Still Standing. HMV Japan. Retrieved on 2010-03 ... Product Search: Still Standing. HMV. Retrieved on 2010-03-21. "Monica Shouts Out Fans & AT&T Appearance". MySpace. Archived ... Product Page: Still Standing Archived 2012-04-05 at the Wayback Machine. Barnes & Noble. Retrieved on 2010-03-21. ...
"Fairphone 3 product page". Fairphone Store. Archived from the original on 2020-06-25. Retrieved 2020-06-25. "Samsung Galaxy S8 ... "Apple Store (U.S.) - iPhone 3G". Archived from the original on 2012-10-10. Retrieved 2013-06-03. "HTC Dream". ... "Apple Store (U.S.) - iPhone 3GS". Archived from the original on 2012-10-10. Retrieved 2013-06-03. "HTC ... Mobile telephones List of Nokia products List of Palm OS devices List of Sony Ericsson products Comparison of Symbian devices ...
Pray, W.S. (2006). Nonprescription Product Therapeutics. Nonprescription Product Therapeutics. Lippincott Williams & Wilkins. p ... ISBN 978-1-305-53719-4. Johnsen, Michael (July 26, 2011). "Dara Torres to serve as brand ambassador to Bengay". Drug Store News ... The product is advised to be used topically for adults and children 12 years of age and older, and no more than 3 to 4 times ... Products containing menthol, methyl salicylate and capsaicin as active ingredients have the potential to cause such burns. The ...
"Nintendo Online Store". Retrieved 2006-04-02. "Nintendo Japan Product Page". Archived from the original on 2006-04-05. ... The device stores the last 7 days of detailed activity statistics, and the last 60 days of total step counts. There is a clip ... Sold at an online Nintendo shop in Japan. It works with all DS and 3DS models. The activity meter is a pedometer included with ... "Products - RT2500 Chipset Solution". Archived from the original on 2006-04-07. Retrieved 2006-04-03. "DSLinux : The home of ...
"Zune HD Product Information". Microsoft Store. Archived from the original on 16 August 2009. "Microsoft XNA Game Studio 3.1 ... The Zune HD is a portable media player in the Zune product family released on September 15, 2009 by Microsoft. It was a direct ... and blue-colored models were available through the online Zune Originals store. Two months later, on November 6, 2009, firmware ...
Eventually Franck decides to give in and lets Victor put a collar around him saying, "This is the best product we have in-store ... "Cosmos Laundromat product page". Blender Store. Retrieved March 24, 2019. Roosendaal, Ton. "Netherlands Film Festival Premiere ...
MN0087830 (Product Number). Retrieved 2011-08-13. Copsey, Robert (2010-05-10). "Rihanna: 'Te Amo'". Digital Spy. Retrieved 2011 ... "Te Amo - Single di Rihanna - Scarica Te Amo - Single su iTunes" (in Italian). iTunes Store. Apple Inc. 2010-06-08. Retrieved ... "Te Amo - Single by Rihanna - Download Te Amo - Single on iTunes". iTunes Store. Apple Inc. 2010-06-08. Retrieved 2010-07-08. " ... "Te Amo - Single by Rihanna - Download Te Amo - Single on iTunes". iTunes Store. Apple Inc. 2010-06-08. Retrieved 2011-08-13. " ...
"Sony store product page". Retrieved 2011-11-03. CS1 maint: discouraged parameter (link) "Sony store product page". ... ... "The Red Digital Camera Company". RED ... "Pro Sony pdf product information" (PDF). Retrieved 2011-11-03. CS1 maint: discouraged parameter (link) "Bones, ...
... accompanied the product's page on the Glassy Store website. Loud Headphones is a company that was founded by professional ... Song is a featured as a sponsored rider on the Glassy Sunhaters sunglasses website and online store, co-owned/co-founded by ... Glassy Store. February 2013. Archived from the original on January 26, 2013. Retrieved February 6, 2013. "About". Loud ... "Shop". Matix Clothing. Matix Clothing. March 2013. Retrieved March 14, 2013. Kailee Bradstreet (September 15, 2013). "SUNDAY ...
In total, 152 stores sell the Armani/Dolci'' products. Over the years, Armani created various limited Armani/Dolci products to ... Armani Exchange products are available exclusively in 270 stores in 31 countries and on the brand's website. Armani designs ... "Products". Armani/Dolci. Armani Group. Archived from the original on 9 April 2016. Retrieved 2 February 2016. "Store Locator". ... In total, 308 independent and franchise Armani stores sell the Armani Junior and Armani Baby products throughout the whole ...
"Products". Queen of Hearts India. "Maheswari Saris - Queen Attire". THE 13th STORE. Retrieved 23 September 2019. "Authentic ...
Product reviews. Digital Trends. Editor. (17 May 2016). You can now tweet or text without a keyboard thanks to the Tap Strap. ... Shop. Irish Examiner. Irish Examiner Ltd, Linn Dubh, Assumption Road, Blackpool, Cork. Ireland. "This robot employment agency ...
... which bans all food products that contain non-nutritive objects embedded within them. John Wood (13 November 2015). "Product ... "Ferrero unveils limited edition gifting and treat lines". Convenience Store. 6 November 2015. Retrieved 1 December 2015. " ... Kinder Joy is a brand within the Kinder line of chocolate products sold by Ferrero. It has a plastic egg-shaped package with a ... In 2011, Ferrero opened a factory in Baramati, India, to make the eggs, in addition to other products including Tic Tacs. In ...
It was released for online music stores on 2 October 2007. The single was a top twenty hit in the United States, reaching ... "Pocketfull of Sunshine product listing". HMV Japan. Retrieved 10 August 2008. "Natasha Bedingfield - Pocketful of Sunshine (CD ... "NB (Bonus Track Version) by Natasha Bedingfield on Apple Music - iTunes". iTunes Store (UK). Retrieved 12 September 2017. " ... it's like being a pirate who's got his hoard of treasure and is sitting on an island where there are no shops to spend it. It ...
Retrieved 2016-09-20.[dead link] "Tom's Product Locator". Snyder's-Lance Product Locator. Snyder's-Lance. 2016. Retrieved 2016- ... "Lance Wins Bid for Tom's Foods". Convenience Store News. EnsembleIQ. 2005-10-19. Retrieved 2016-09-20. "Kurt Angle Replacing AJ ... Tom's products include potato chips, corn chips, fries, tortilla chips, and pork skins. Additionally, Bugles are manufactured ... As of 2016[update], Tom's products are distributed across the country by Snyder's-Lance. Tom's Snacks is the first mainstream ...
Dan Bennett (May 9, 2004). "Ariztical expanding with gay product.(Gay & Lesbian)". Video Store. Archived from the original on ... In 2003, he joined with various finalists from the first two seasons of the series for a promotional tour of select shopping ... which he and a selection of other finalists from the first two seasons of the series performed across the country in shopping ...
In many product reviews, users complained of multiple bugs in the initial release of the pack. One of the bugs, which occurs ... Currently, there are over 200 add-ons for FSX: Steam Edition from over 35 developers available on the Steam store including ... "Flight Simulator X - Product Information". Microsoft Game Studios. 2010. Archived from the original on January 1, 2011. ... On January 22, 2009, it was reported that development team behind the product was being heavily affected by Microsoft's ongoing ...
"Assuranceforeningen Gard". Store norske leksikon. Retrieved August 1, 2017. https://www.igpandi ...
"ASUS UK Online Store". Retrieved 10 January 2021. "Microsoft and Google ruin Intel's plan for dual-OS tablets". The Verge. Mar ... "Asus Transformer Book - product list". Archived from the original on November 2, 2014. Retrieved November 3, 2014. " ...
"Product Info", Online Store, Quantum. DLTtape Handbook (PDF) (8th ed.), Quantum, 2001. DLT Roadmap (archived from 2006) at ...
Wal-Mart Stores, Inc., Continental Airlines, Inc., Valero Marketing & Supply, Car Son Bay LP, Memorial NW Pavilion Trust, ... chemical processing sites producing a variety of petrochemical products. The Cedar Bayou plant, in operation since 1963, is ... and Rollingbrook Drive connecting most of Baytown's major shopping areas with Lee College. ...
The book argues that many products would not be sold if properly labeled, and this failure to police product labeling has been ... Examples cited include beauty products, which in the first quarter of the 20th century were found to contain arsenic, lead and ... The book's key proposition is that a significant portion of the products sold to the public-particularly pharmaceuticals and ... The authors also question the value of statements made by scientists who vouch for the safety of products, citing the example ...
... but do not offer advantages compared with diets which allow moderate amounts of animal products.[100] There is not enough ... reduced saturated fat and low-fat dairy products, and with a macronutrient intake tailed to the individual, to distribute ...
AP-X - designed by Air Products & Chemicals, Inc. (APCI). *AP-SMR (Single Mixed Refrigerant) - designed by Air Products & ... Industry practice is to store LNG as a boiling cryogen. That is, the liquid is stored at its boiling point for the pressure at ... If the annual contract quantity is confirmed, the buyer is obliged to take and pay for the product, or pay for it even if not ... The intention was to store natural gas as a liquid so it could be used for shaving peak energy loads during cold snaps. Because ...
... has investments in approximately 60 Welkoop Stores selling agricultural products. website Agrifirm website NCR Annual ... Horticulture (bulbs, vegetables and fruit): fertilizers, pesticides and industrial products. Livestock Cattle sector: feed for ... Agrifirm provides products and services in the following areas: Arable farming: seeds, fertilizers and pesticides. In addition ... established on 13 April 1909 with the purpose of taking advantage on joint purchasing and sales of agricultural products and ...
Rex Book Store. p. 58. ISBN 978-971-23-3563-1.. *^ Elser, J.; Hayakawa, K.; Urabe, J. (2001). "Nutrient Limitation Reduces Food ... In food web terminology, complexity is a product of the number of species and connectance.[70][71][72] Connectance is "the ... as well as products secreted, excreted or exuded from organisms (e.g. extra-cellular polymers, nectar, root exudates and ... webs more nutrient limited than detrital food webs where bacteria are able to access and release the nutrient and energy stores ...
... includes not just the use of plant products, but may also include the use of animal and mineral products.[74] It is among the ... through health shops and pharmacies as 'nutritional supplements'.... Only a tiny minority of these remedies have been shown to ... animal and fungal products, and minerals, including use of these products in traditional medical practices that may also ... FDA, Use Caution With Ayurvedic Products *^ Niggemann, B.; Grüber, C. (22 February 2003). "Side-effects of complementary and ...
... the product of two or more genes, and their environment.[2] These QTLs are often found on different chromosomes. The number of ...
wood products and packaging. *food processing. *metallurgy. References[edit]. *^ Juan José Larrea, Pierre Bonnassie: La Navarre ...
In the simplest form of three-strand braid, all the hair is initially divided into three sections, which are then simultaneously gathered together near the scalp. In contrast, a French braid starts with three small sections of hair near the crown of the head, which are then braided together toward the nape of the neck, gradually adding more hair to each section as it crosses in from the side into the center of the braid structure. The final result incorporates all of the hair into a smoothly woven pattern over the scalp. If the main mass of hair is initially parted into two or more sections along the scalp that are kept separate from one another, multiple French braids may be created, each in its own section. One unique feature about the French braid is that an individual can braid their own hair without the help of others. The difficulty of braiding can depend on the type of hair the individual has, some styles of hair are easier to braid than others. The length of hair also plays a role in the ...
"History of Product Names & Trademarks: Arm & Hammer Baking Soda".. *^ "The Straight Dope: Did tycoon Armand Hammer have ... Arm & Hammer is a registered trademark of Church & Dwight, a major American manufacturer of household products. The logo of ... Originally associated solely with baking soda and washing soda, the company began to expand the brand to other products in the ... The new products included toothpaste, laundry detergent, underarm deodorant, and cat litter. ...
It is over 50% apple juice, making it a similar product to Magners and Stella Cidre.[13] It also contains glucose syrup, ...
Their food was brought to them and provided through the only shop that remained open in the country.[309] Pol Pot saw the Khmer ... and the highest echelons of the party had access to imported luxury products.[272] ... Cooperative stores selling goods like medicines, cloth, and kerosene were formed, providing goods imported from Vietnam.[176] ...
Note: To test divisibility by any number expressed as the product of prime factors p. 1. n. p. 2. m. p. 3. q. {\displaystyle p ... Multiply by 5, add the product to the next digit to the left. Set down that result on a line below that digit. Repeat that ... and adding the products (1×1 + 7×3 + 3×2 = 1 + 21 + 6 = 28). The original number is divisible by 7 if and only if the number ... method of multiplying the units digit by five and adding that product to the number of tens. Add the result to the next digit ...
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products,[1] including ... Sears, Justin E.; Boger, Dale L. (2015). "Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and ... "Recent applications of Cp2TiCl in natural product synthesis". Organic Chemistry Frontiers. 1 (1): 15-33. doi:10.1039/c3qo00024a ...
He went at the request of Edith Nourse Rogers who was responsible for the lifting of an embargo of aviation products to Mexico ... His corpse was wrapped in canvas from the plane's fuselage and taken to a garage behind Willis Jefferson Buzby's General Store ...
Leaves can also store food and water, and are modified accordingly to meet these functions, for example in the leaves of ... The products of photosynthesis are called "assimilates". In ferns and most flowering plants, the mesophyll is divided into two ... Leaves also function to store chemical energy and water (especially in succulents) and may become specialized organs serving ... Succulent leaves store water and organic acids for use in CAM photosynthesis. ...
A typical warehouse or distribution center will receive stock of a variety of products from suppliers and store these until the ... Motion check weighers may be used to reject cases or individual products that are under or over their specified weight. They ... Factory automation with KUKA industrial robots for palletizing food products like bread and toast at a bakery in Germany ... Examples include automated storage and retrieval systems, which simply use cranes to store and retrieve identified cases or ...
The Thatcher filing was then followed by an FDA filing by BRC Operations PTY Limited, with their BRC Software Product[8] in ...
... is featured on many of their products, which are available through multiple retailers and their own stores. The firm is ... The retail stores host events throughout the year: The Winter Coat Drive, The Annual Book Drive, Earth Day and College Nite.[ ... The firm was formally incorporated in 1998 and has since grown into a global brand with its own stores. On Nov. 8, 2005, Frank ... The company continues to design products intended to reflect the original ethos from the garage days - applying themes from ...
... the body of literature that used these approaches seem to have mistaken and interpreted mathematical artifacts as the products ...
... spending as part of total U.S. healthcare spending (public and private). Percent of gross domestic product (GDP). ...
... hunting and gathering people ate varying proportions of vegetables (including tubers and roots), fruit, seeds (including nuts and wild grass seeds) and insects, meat, fish, and shellfish.[96][97] However, there is little direct evidence of the relative proportions of plant and animal foods.[98] Although the term "paleolithic diet", without references to a specific timeframe or locale, is sometimes used with an implication that most humans shared a certain diet during the entire era, that is not entirely accurate. The Paleolithic was an extended period of time, during which multiple technological advances were made, many of which had impact on human dietary structure. For example, humans probably did not possess the control of fire until the Middle Paleolithic,[99] or tools necessary to engage in extensive fishing.[citation needed] On the other hand, both these technologies are generally agreed to have been widely available to humans by the end of the Paleolithic (consequently, ...
I found that they formed invariant products of not one but two distinct kinds. ... The first group of limits were calculable a ...
He and his family later initiated Key to Freedom, a project which tries to "find a route to market for products made by WIF."[ ...
Melnik BC (2011). "Evidence for Acne-Promoting Effects of Milk and Other Insulinotropic Dairy Products". Milk and Milk Products ... Hammer KA (February 2015). "Treatment of acne with tea tree oil (melaleuca) products: a review of efficacy, tolerability and ... and product selection". The Journal of Clinical and Aesthetic Dermatology. 6 (12): 19-27. PMC 3997205. PMID 24765221.. ... Combination products use benzoyl peroxide with a topical antibiotic or retinoid, such as benzoyl peroxide/clindamycin and ...
Urinals have primarily been offered in public toilets for males, with female urinals being only a niche product so far. ... and sanitary bins for the disposal of menstrual hygiene products for women and girls. Sanitary bins may easily be included in ...
"Genentech: Products - Product Information - Immunology - Rituxan RA Full Prescribing Information". Archived from the original ...
Mother Records · The Dalton Brothers · Automatic Baby · Elevation Partners · DATA · EDUN · ONE Campaign · Product Red · Music ... Target Stores to Offer Exclusive U2 7 CD». PR Newswire. 17 de janeiro de 2002. Consultado em 5 de fevereiro de 2012. ... 7 é um EP da banda de rock irlandesa U2, lançado com exclusividade pela Target Stores nos Estados Unidos em 2002. Ela recolhe ...
In 2014, according to the World Marrow Donor Association (WMDA), stem cell products provided for unrelated transplantation ...
Need help with a Microsoft Store product, subscription, or service? Learn how to get in touch with Microsoft experts via live ... You are shopping Microsoft Store in: Canada - English. Are you looking for Microsoft Store in: United States - English? ... You are shopping Microsoft Store in: Canada - English. Are you looking for Microsoft Store in: United States - English? ... Microsoft Software Support - Product Help - Microsoft Store. Skip to main content Microsoft Home ...
... and NSTA Kids books in the online Science Store.. Use promo code SHIP18 when you check out online.. (Offer valid on orders ...
Use promo code SHIP18 when you check out in the online Science Store.. (Offer valid on orders placed for NSTA Press books and e ...
To protect your order during transit, products of different publication types and sizes may be shipped in separate packages. ...
... online store. We have been a pipe, valve, and fitting distributor throughout Florida for over 25 years. Our items are NOT ... Welcome to Florida Industrial Products online store. We have been a pipe, valve, and fitting distributor throughout Florida ... Florida Industrial Products. 4followersfloridaip(72floridaips feedback score is 72) 100.0%floridaip has 100% Positive Feedback ...
Dining: over 57,000 offers! Shopping & Services: over 78,00 offers! Events & Attractions: over 61,000 offers! Health & Beauty: ...
Im trying to build an online store to sell digital downloads, videos specifically. The process itself is very intuitive and ... I dont understand why you are putting the Vimeo URL in the product data? Are you checking out people via your online store and ... I dont understand why you are putting the Vimeo URL in the product data? Are you checking out people via your online store and ... If you are or will be looking for advanced cart features with regard to product displays, product groupings, and customer ...
Products Required product attributes are primarily defined by the products feed specification. See the Products Feed ... product/. price/. currency. string. The currency of the price.. writable product/. product_type. string. Your category of the ... internalReason, ,/warning, (/foreach) ,/product,. Property name. Value. Description. Notes. product. object. Product data. ... product/. id. string. The REST id of the product. Content API methods that operate on products take this as their productId. ...
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SecurityFocus is designed to facilitate discussion on computer security related topics, create computer security awareness, and to provide the Internet's largest and most comprehensive database of computer security knowledge and resources to the public. It also hosts the BUGTRAQ mailing list.
Visit Amazon Products Shopping In Pakistans CaringBridge website where youll find the latest updates and a place to share ...
Store type. Tobacco stores, supermarkets and grocery stores, convenience stores, gas stations with convenience stores, other ... you can select store types that typically sell tobacco products (tobacco stores, supermarkets and grocery stores, convenience ... Product placement. Self-service of products. Ability for customers to access products without clerk assistance. Examples ... Include logistic details such as how to use store lists, obtaining transportation to and between stores, how to enter a store, ...
COLES is set to launch a major new marketing promotion featuring miniature versions of popular products like Nutella, Vegemite ... Little Shop features 30 iconic, household brands - including Vegemite, Nutella and Weet-Bix - which are shrunk down into a mini ... "Little Shop is a collectible campaign which has been run successfully in several countries, including The Netherlands in 2012, ... The supermarket is hoping to emulate the success of Woolworths animal cards and Marvel superhero discs with its Little Shop ...
... the chains Whole Body shops are laying claim to their complexions. ... The Whole Body shop in Chelsea, shown here, sells natural beauty products like Alaffias Authentic African Black Soap. The shop ... Local buyers help decide each stores product lineup; the companys goal is to have 20 percent of its beauty products made in ... Body Shop oils anyone?) I dabbed some on. A nearby sales representative for Buttercup & Jake, a line of all-natural products ...
product.ModelName}} Select {{product.UnitCost , currency : $ : 2}} {{product.SalePrice , currency : $ : 2}} {{product. ... BPS Store Grid View List View 2019 Bioenergetics, Mitochondria & Metabolism Subgroup sku Product SKU: DUES-ENERG-2019 The ... sku Product SKU: DUES-BIOPOLYMERDIN-2020 Dinner Pricing Chart. All fees shown are. in U.S. dollars. 2020 Biopolymers in vivo ... sku Product SKU: DUES-BENGDIN-2020 Dinner Pricing Chart. All fees shown are. in U.S. dollars. 2020 Bioengineering Dinner Price ...
product.ModelName}} Select {{product.UnitCost , currency : $ : 2}} {{product.SalePrice , currency : $ : 2}} {{product. ... BPS Store Grid View List View 2020 Bioenergetics, Mitochondria & Metabolism Subgroup sku Product SKU: DUES-ENERG-2020 The ... Product Name. Unit Cost. Qty. Line Total. {{cartItem.ProductSku}}. {{cartItem.ProductName}}. {{cartItem.UnitCost , currency ... sku Product SKU: DUES-FLUORES-2020 Fluorescence is one of the few methods that allow one to observe interactions between very ...
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  • There have been no reported illnesses to date and all stores have removed these items form sale and have begun alerting customers. (
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  • Under the new rules , retailers and vape producers will not be able to characterize vape products as safe, clean, harmless or healthy. (
  • Shop owners also will be limited in the advertising they can do for vape products. (
  • Under the new restrictions, stores would have to sell flavored nicotine vape products in "age-restricted" areas. (
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  • Another source of store lists is each state's publicly available Synar report (15).Although these annual reports required by the federal government focus on compliance with youth access laws, they also contain information on the sampling strategy used to identify stores (eg, this report [16] describes California's approach), which may help you find a source to create your own list. (
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  • The natural way to help reduce the redness is to find products that contain emu oils and herbs, but it's always best to consult a professional before using lotions or cream, because each individual reacts differently to natural ingredients. (
  • You'll find all 5 products available as part of the John Lewis & Partners October Beauty Edit, available to shop in-store or online . (
  • though there are bathroom staples in the $5 range like Tom's of Maine toothpaste and Burt's Bees lip balm in the store, many cosmetics and creams bear the double-digit price tags usually found at department store beauty counters. (
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  • Between now and April 30, 2018, get free shipping when you order $75 or more of NSTA Press ® and NSTA Kids books in the online Science Store. (
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  • Website Reviews Minzy Store Masks Reviews [April] - Is It A Legit Product? (
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  • The website is offering free shipping over $60, which means if you purchase more three minzy store masks , you will get a free shipping facility. (
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  • Science in Sport® is a leading sports nutrition company that develops, manufactures, and markets innovative sports supplements and nutrition products for use by professional athletes and sports enthusiasts. (
  • In a state House Oversight Committee meeting last week, Mark Slis, owner of the 960 Vapor shop in Houghton, said since buying the shop, he has saved 1,000 people from smoking and that 99% of his customers use flavored vapes. (
  • The FDA classifies nicotine products including e-cigarettes and other electronic vapor devices as tobacco products. (
  • The other was the new Clarisonic Sonic Foundation Brush which transforms any Clarisonic device from a sonic cleanser to a makeup applicator and can be used with a variety of liquid and cream based makeup products from primers to foundations, blushes and even contour/highlight - how cool is that? (
  • Kim showed off this new brush that transforms any Clarisonic device from a sonic cleanser to a makeup applicator and can be used with a variety of liquid and cream based makeup products from primers to foundations, blushes and even contour/highlight. (
  • Makeup products that multi-task can help make your beauty routine more efficient - that's where this "huestick" comes in. (
  • Most products on Allegro Medical qualify for our offers. (
  • Retailers like Allegro Medical have the legal right to sell products at prices we set. (
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  • There are 348 departments nationwide and three stand-alone stores, including the one in Chelsea. (
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  • It best suits for handmade soap shop, but it can be also interesting for handmade jewelry and accessories store, clothing store or crafts shop. (
  • The Whole Body shop in Chelsea, shown here, sells natural beauty products like Alaffia's Authentic African Black Soap. (
  • The Ace Hardware Corporation also sells Cabot wood stain products at retail stores and lists them on the company website. (
  • Menards sells Cabot wood stain products in 1- and 5-gallon containers, as well as in smaller containers. (
  • As of 2015, Wal-Mart is the only store that sells Great Value products. (
  • Additional categories of the item (formatted as in products feed specification ). (
  • Allows advertisers to override the item URL when the product is shown within the context of Product Ads. (
  • Experts will tell you that isolating the product is crucial, and this is true for the most part, but if you're selling clothing, pairing the item with props can make it more interesting and even give potential buyers ideas on how to pair the item with accessories. (
  • After sending out an email to developers earlier in the week detailing App Store price changes coming to a few territories, Apple has today raised the price of apps in all countries within the European Union, Norway, Russia, and Canada. (
  • The price of the least expensive paid apps in the App Store, which are priced at $0.99 in the United States, moved from £0.69 to £0.79 in the UK, €0.89 to €0.99 in EU countries, and $0.99 to $1.19 in Canada, with similar price increases hitting the likes of Norway and Russia. (
  • Exclusions may include, but are not limited to, shipping options, products of certain size, weight, manufacturer price restrictions or products with savings/discounts already applied. (
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  • In recent years, tobacco control groups have become increasingly interested in the point of sale (POS), or the stores in which tobacco products are sold. (
  • FDA Commissioner Scott Gottlieb on Monday named Walgreens, 7-Eleven, and Exxon, among more than a dozen stores, for repeatedly selling tobacco products to minors. (
  • In response to questions from ABC News, Walgreens said it's making their tobacco products less prominently displayed in stores and has taken action to promote tobacco alternatives. (
  • We have a zero tolerance policy prohibiting the sale of tobacco products to minors and any employee violating this policy is subject to immediate termination," Walgreen company spokesperson Jim Cohn said in a statement. (
  • Make your way to the Site to Store desk, where an as. (
  • The user-friendly, vibrant site taps into the magic of the classic Wizard of Oz story and features hundreds of special needs products for children of all ages and abilities. (
  • To protect your order during transit, products of different publication types and sizes may be shipped in separate packages. (
  • Order your favourite products online and select the "collect in store" option. (
  • Remember, one should be well informed about the product and selling web store, before making any order! (
  • You clicked on an external link, which has been disabled in order to keep your shopping session open. (
  • Target continually tests new in-store experiences and programs in order to gather insights that we can use to enhance our guests' experience. (
  • How do you pick up an order from a Wal-Mart store? (
  • To pick up an online order from a Wal-Mart store, go to the location you designated during your order. (
  • The best way to order decorated cakes from Wal-Mart is to visit the local Wal-Mart bakery, but most stores also accept orders by telephone. (
  • The mobility division of New Line Products LLC, The Lift Store USA, has now been split into two divisions in order to effectively handle the increased demand in the DIY market. (
  • Please select your store to see pricing and to order online. (
  • Little Shop is a collectible campaign which has been run successfully in several countries, including The Netherlands in 2012, New Zealand 2013 and 2014, and South Africa in 2016 and 2017," he said in a client note. (
  • With an on-time delivery rate of 99 percent and a first-pass-quality yield of 98 percent, the shop finished about 38 million parts in 2017, which includes about 1,200 different types of parts. (
  • The product enables a manufacturer to connect all of its CNC machine tools and controllers (regardless of brand) and monitor and manage each machine's data in real time and transmit that data to the company's ERP system. (
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  • Store observation projects range from single neighborhoods to cities or even entire states. (
  • Coles will launch the Little Shop collectible range this week. (
  • The supermarket is hoping to emulate the success of Woolworths' animal cards and Marvel superhero discs with its 'Little Shop' range of collectibles hitting stores on Wednesday. (
  • The Coles Little Shop collectible range. (
  • But Beekman 1802's goat's-milk beauty range is extensive, with more than a hundred products. (
  • Menards carries a complete range of Cabot wood stain products. (
  • They boast restorative properties and include a variety of fragrances, as well as a range of hand and foot products. (
  • Hear first-hand about exclusive product launches, new scents, and more! (
  • I would like to be contacted with the latest marketing information (product launches, new scents, etc. (
  • Kim Kardashian , 36, shared some of her all time beauty faves and new product launches on Snapchat and all of her fave picks some of her fave picks are from the drugstore! (
  • With over 60 manufacturer partners, many who specialize in IVF product innovation, development and production. (
  • Amongst innovation services, in-store customization is expanding in various CPG and retail segments. (
  • After days of Champagne and late nights, the thought of rejuvenating with natural beauty products had conjured visions of "Sound of Music" bliss, but the aisles were jammed with more labels and products than I could easily navigate. (
  • Kim Kardashian has been unboxing a ton of beauty products on her Snapchat & they're all from the drugstore - how amazing is that? (
  • About EMP: Since 1972, Emergency Medical Products, Inc. has been a trusted distributor of EMS supplies, first aid products, and other pre-hospital and emergency medical supplies and equipment. (
  • Lowe's and Menards offer Cabot wood stain products online and at retail locations. (
  • The new measures come after Gottlieb has reportedly taken steps towards enacting a plan to restrict flavored e-cigarettes and ban menthol cigarettes in stores across the country. (
  • Use the Store Locator to add store locations. (
  • Shopping & Services: over 78,00 offers! (
  • You agree to receive occasional updates and special offers for The New York Times's products and services. (
  • Shipping offers vary by store. (
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  • Lifestyle and Physical Development offers programs, professionals, products and consulting services for business and individuals. (
  • Conception products like Rinovum Women's Health's Stork OTC may carve out a new category in the OTC space. (
  • That philosophy also has helped Great Lakes earn special recognition in the Products Finishing Top Shops Benchmarking Survey in the Finishing Practices category for its outstanding scores in several areas. (
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  • Product specifications are obtained from merchants or third parties and although we make every effort to present accurate information, MyShopping is not responsible for inaccuracies. (
  • To make shopping easy and convenient, they have recently launched a brand new, easy to use website - . (
  • That's why it's so important to make sure that your product photos are high-quality and eye-catching. (
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  • You can also get in-store personal training and expert advice on purchases. (
  • Microsoft Store Support has answers to common questions about subscriptions, orders, and purchases and support phone numbers for your locale. (
  • Free Standard Shipping is valid in the 48 contiguous United States on purchases of $60 or more when you shop with a representative, or $8 flat rate for purchases under $60. (
  • Track your in-store purchases. (
  • Little Shop features 30 iconic, household brands - including Vegemite, Nutella and Weet-Bix - which are shrunk down into a mini collectible for customers to collect and swap. (
  • For too long, companies have gotten our kids hooked on nicotine by marketing candy-flavored vaping products as safe. (
  • The 16th annual Drug Store News Industry Issues Summit on Dec. 2 is shaping up to be a must-attend event. (
  • Sign up to receive beauty news, product samples, coupons and more. (
  • Includes news, chat forums, health quizzes and consumer product updates. (
  • By clicking sign up, I agree that I would like to hear from Microsoft and its family of companies about Microsoft Store and other Microsoft products and services. (
  • Prices and availability of products and services are subject to change without notice. (
  • About IVF Store IVF STORE is an IVF-dedicated eCommerce portal offering a full assortment of IVF products and services exclusively designed for Assisted Reproductive Technology (ART) professionals. (
  • Finally when you are on an individual product review page, I see the Vimeo video embedded and below the player are two additional thumbnails, one to the video itself and one to display the product thumbnail. (
  • For a look at some hot new pharmacy tech products, see page 26. (
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  • Once upon a time, the beauty aisle of a health-food store was something of an oxymoron, stocked with dubious image boosters like powdered henna and Dr. Bronner's soap. (
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  • The shops obviously have a map to be reached, opening hours and their own interactive brand-list. (
  • Your store list does not contain any store locations. (
  • Decoding the science so you don't have to, here are the 5 new products that should go straight to the top of your shopping list. (
  • It might be one of the pricier products on the list, but La Prairie Skin Caviar really is the Rolls-Royce of eye-based skincare. (
  • The list of products is usually extensive, and they've all been editor-tested and approved so that readers can trust the results. (
  • Three delicately scented products for body and hands in a keepsake metallic bauble. (
  • Handily, John Lewis & Partners' October Beauty Edit has brought together a carefully curated collection of skincare heroes: particularly powerful products designed to target a whole host of specific needs. (
  • At The Body Shop, we believe that self love is our superpower that lifts us up to fight for change together. (
  • Champneys, a spa established in 1925, recently brought its 90-year heritage in health and beauty stateside with the introduction of a line of bath and body products at Target. (
  • the Xomega body cream and Optyma Lip ( $23 in the TIA shop ). (