Heart Valves: Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.Heart Valve Prosthesis: A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).Aortic Valve: The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Mitral Valve: The valve between the left atrium and left ventricle of the heart.Heart: The hollow, muscular organ that maintains the circulation of the blood.Bioprosthesis: Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.Heart Valve Prosthesis Implantation: Surgical insertion of synthetic material to repair injured or diseased heart valves.Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)Pulmonary Valve: A valve situated at the entrance to the pulmonary trunk from the right ventricle.Mitral Valve Stenosis: Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Tricuspid Valve: The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.Coronary Stenosis: Narrowing or constriction of a coronary artery.Spinal Stenosis: Narrowing of the spinal canal.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.Pulmonary Valve Stenosis: The pathologic narrowing of the orifice of the PULMONARY VALVE. This lesion restricts blood outflow from the RIGHT VENTRICLE to the PULMONARY ARTERY. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.Tracheal StenosisPyloric Stenosis: Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.Mitral Valve Prolapse: Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Calcinosis: Pathologic deposition of calcium salts in tissues.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Venous Valves: Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Tricuspid Valve Insufficiency: Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Heart Transplantation: The transference of a heart from one human or animal to another.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Anticoagulants: Agents that prevent clotting.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Rheumatic Heart Disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.Aortic Stenosis, Subvalvular: A pathological constriction occurring in the region below the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Echocardiography, Transesophageal: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Renal Artery Obstruction: Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Cardiac Surgical Procedures: Surgery performed on the heart.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Mitral Valve Annuloplasty: A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annulus of the MITRAL VALVE. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.Fetal Heart: The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time.Aortic Stenosis, Supravalvular: A pathological constriction occurring in the region above the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.International Normalized Ratio: System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.Endocardial Cushions: A fetal heart structure that is the bulging areas in the cardiac septum between the HEART ATRIA and the HEART VENTRICLES. During development, growth and fusion of endocardial cushions at midline forms the two atrioventricular canals, the sites for future TRICUSPID VALVE and BICUSPID VALVE.Endocardium: The innermost layer of the heart, comprised of endothelial cells.Heart Sounds: The sounds heard over the cardiac region produced by the functioning of the heart. There are four distinct sounds: the first occurs at the beginning of SYSTOLE and is heard as a "lubb" sound; the second is produced by the closing of the AORTIC VALVE and PULMONARY VALVE and is heard as a "dupp" sound; the third is produced by vibrations of the ventricular walls when suddenly distended by the rush of blood from the HEART ATRIA; and the fourth is produced by atrial contraction and ventricular filling.Echocardiography, Doppler, Color: Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.Heart Valve Prolapse: Downward displacement of any one of the HEART VALVES from its normal position. This usually results in failed valve closure.Cardiac Valve Annuloplasty: A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annuli of HEART VALVES. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.Acenocoumarol: A coumarin that is used as an anticoagulant. Its actions and uses are similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p233)Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Multidetector Computed Tomography: Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Carotid Artery, Internal: Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.Angioplasty, Balloon: Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.Pregnancy Complications, Cardiovascular: The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.Endarterectomy, Carotid: The excision of the thickened, atheromatous tunica intima of a carotid artery.Phonocardiography: Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Laryngostenosis: Developmental or acquired stricture or narrowing of the LARYNX. Symptoms of respiratory difficulty depend on the degree of laryngeal narrowing.Amaurosis Fugax: Transient complete or partial monocular blindness due to retinal ischemia. This may be caused by emboli from the CAROTID ARTERY (usually in association with CAROTID STENOSIS) and other locations that enter the central RETINAL ARTERY. (From Adams et al., Principles of Neurology, 6th ed, p245)Discrete Subaortic Stenosis: A type of constriction that is caused by the presence of a fibrous ring (discrete type) below the AORTIC VALVE, anywhere between the aortic valve and the MITRAL VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Tricuspid Valve Stenosis: The pathologic narrowing of the orifice of the TRICUSPID VALVE. This hinders the emptying of RIGHT ATRIUM leading to elevated right atrial pressure and systemic venous congestion. Tricuspid valve stenosis is almost always due to RHEUMATIC FEVER.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Angiography: Radiography of blood vessels after injection of a contrast medium.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.Embolism: Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Bioreactors: Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.Ultrasonography, Doppler, Transcranial: A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.Carcinoid Heart Disease: Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Heart Block: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.Papio ursinus: A species of baboon in the family CERCOPITHECIDAE found in southern Africa. They are dark colored and have a variable social structure.Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.Embolism, Air: Blocking of a blood vessel by air bubbles that enter the circulatory system, usually after TRAUMA; surgical procedures, or changes in atmospheric pressure.Chordae Tendineae: The tendinous cords that connect each cusp of the two atrioventricular HEART VALVES to appropriate PAPILLARY MUSCLES in the HEART VENTRICLES, preventing the valves from reversing themselves when the ventricles contract.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Balloon Valvuloplasty: Widening of a stenosed HEART VALVE by the insertion of a balloon CATHETER into the valve and inflation of the balloon.Pyloric Stenosis, Hypertrophic: Narrowing of the pyloric canal due to HYPERTROPHY of the surrounding circular muscle. It is usually seen in infants or young children.Decanoates: Salts and esters of the 10-carbon monocarboxylic acid-decanoic acid.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Hemorrhage: Bleeding or escape of blood from a vessel.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Receptor, Serotonin, 5-HT2B: A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to the action of the 5-HT2B receptor including the development of cardiac myocytes (MYOCYTES, CARDIAC) and the contraction of SMOOTH MUSCLE.Heart Arrest, Induced: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).Safety-Based Drug Withdrawals: Removal of a drug from the market due to the identification of an intrinsic property of the drug that results in a serious risk to public health.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Angiography, Digital Subtraction: A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).Esophageal Stenosis: A stricture of the ESOPHAGUS. Most are acquired but can be congenital.Intracranial Embolism and Thrombosis: Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.Equipment Design: Methods of creating machines and devices.Stress, Mechanical: A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.Recurrence: The return of a sign, symptom, or disease after a remission.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Fenfluramine: A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.Extracellular Matrix: A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Tensile Strength: The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)Angioplasty: Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.Bioartificial Organs: Artificial organs that are composites of biomaterials and cells. The biomaterial can act as a membrane (container) as in BIOARTIFICIAL LIVER or a scaffold as in bioartificial skin.Intracranial Arteriosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Tissue Preservation: The process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).Postoperative Period: The period following a surgical operation.Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Coronary Vessels: The veins and arteries of the HEART.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Biomedical Engineering: Application of principles and practices of engineering science to biomedical research and health care.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Hemorheology: The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.Tissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Prothrombin Time: Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Ileocecal Valve: The valve, at the junction of the CECUM with the COLON, that guards the opening where the ILEUM enters the LARGE INTESTINE.Fractional Flow Reserve, Myocardial: The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.Pulmonary Valve Insufficiency: Backflow of blood from the PULMONARY ARTERY into the RIGHT VENTRICLE due to imperfect closure of the PULMONARY VALVE.Echocardiography, Three-Dimensional: Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.Carotid Arteries: Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.Systole: Period of contraction of the HEART, especially of the HEART VENTRICLES.Intracranial Embolism: Blocking of a blood vessel in the SKULL by an EMBOLUS which can be a blood clot (THROMBUS) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with HEART DISEASES. Other non-cardiac sources of emboli are usually associated with VASCULAR DISEASES.Vertebrobasilar Insufficiency: Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Sternum: A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Heart Septal Defects: Abnormalities in any part of the HEART SEPTUM resulting in abnormal communication between the left and the right chambers of the heart. The abnormal blood flow inside the heart may be caused by defects in the ATRIAL SEPTUM, the VENTRICULAR SEPTUM, or both.Heart Injuries: General or unspecified injuries to the heart.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Endocarditis, Subacute Bacterial: ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Observer Variation: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).Cardiac-Gated Imaging Techniques: Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)Prosthesis-Related Infections: Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).Rheology: The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Phenindione: An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.Sus scrofa: A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Aortic Valve Prolapse: The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.Hypertension, Renovascular: Hypertension due to RENAL ARTERY OBSTRUCTION or compression.Arteriovenous Shunt, Surgical: Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Organogenesis: Formation of differentiated cells and complicated tissue organization to provide specialized functions.Pulmonary Subvalvular Stenosis: Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. It is characterized by restricted blood outflow from the RIGHT VENTRICLE into the PULMONARY ARTERY, exertional fatigue, DYSPNEA, and chest discomfort.Cardiotonic Agents: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Heart, Artificial: A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)Pulsatile Flow: Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.Aorta: The main trunk of the systemic arteries.Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Collagen: A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Black Russian Terrier
Bartolomeu Anania
හෘද රෝග - විකිපීඩියා, නිදහස් විශ්වකෝෂය
Premature junctional contraction
Heart valve stenosis | pathology | Britannica
BICUSPID PULMONARY VALVE IN ASSOCIATION WITH CALCIFIC AORTIC STENOSIS | Heart
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Severe Bioprosthetic Mitral Valve Stenosis and Heart Failure in a Young Woman with Systemic Lupus Erythematosus
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Aortic Valve Stenosis: "Guidelines" | Heather Pemberton, MD | Texas Heart Institute
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VHD: What are heart valve diseases? Health insights | Withings
Diagnosed with aortic stenosisSymptoms of aorticSeverityPulmonary valveRheumatic feverTAVRProstheticFlapsMinimallyTricuspid valve stLeakyLungsAbnormalAtrialBicuspid aortiComplicationsNarrowsCardiacSurgeryValvular stenosisCongenital heartBalloon valvuloplastyNarrowing of the heart'sKnown as mitral valve stPatients with severeShortnessHeart's aortic valveArtificial HeartDiagnosisMitral and tricuspidOccursLeft ventricularAortic valvesTreatmentsTranscatheter Aortic Valve Implantation
Diagnosed with aortic stenosis2
- If you are diagnosed with aortic stenosis, your team of cardiologists and cardiovascular surgeons at CHI St. Vincent will work closely with you to determine the approach that provides you with the best outcome. (chistvincent.com)
- If you've been diagnosed with aortic stenosis (AS), there's good news: Today's treatments can get even the oldest, frailest patients relishing life again! (healthmonitor.com)
Symptoms of aortic5
- The typical symptoms of aortic stenosis include angina, syncope, and heart failure. (annals.org)
- Signs and symptoms of aortic valve stenosis usually appear when a valve is severely narrowed. (chistvincent.com)
- Look below for signs and symptoms of aortic stenosis. (chistvincent.com)
- In addition to the symptoms of aortic stenosis, which may cause a patient to feel faint, weak, or lazy, the wall of the left ventricle may also show muscular thickening due to the ventricle working harder to pump blood through the narrow valve opening into the aorta. (merillife.com)
- Those who have not developed symptoms of aortic stenosis must be monitored carefully with regular checkups. (freemd.com)
Severity14
- Depending on the severity of your stenosis and your age, valvuloplasty, which uses a balloon to inflate the valve, may be an option. (healthline.com)
- Symptoms of heart valve disorders vary depending on the severity of the disorder. (healthline.com)
- As the severity of AS increases, doctors will likely recommend replacement of the aortic valve. (midmichigan.org)
- The provider will grade the severity of the valve stenosis to plan treatment. (medlineplus.gov)
- Aortic valve replacement was associated with significant improvement in left ventricular ejection fraction, the severity of PHT and NYHA functional class. (onlinejacc.org)
- Echocardiogram (echo) - uses sound waves to produce images of the pulmonary valve, the test can determine the severity of the stenosis. (mercy.com)
- Natural History of Aortic Valve Stenosis of Varying Severity in the Elderly. (bostonscientific.com)
- Depending on the severity of the leakage, this situation can lead to progressive lung congestion and congestive heart failure. (hopkinsmedicine.org)
- The severity of aortic insufficiency can sometimes be reduced with medications, but aortic stenosis has no effective medical therapy. (hopkinsmedicine.org)
- Serum OPG could be a valuable biomarker in the evaluation of severity of calcified AS and serve as an additional indicator besides clinical presentation and echocardiography in the assessment of surgical treatment or aortic valve replacement. (kbco.hr)
- The severity of aortic stenosis increases with age and can be classified as mild, moderate, and severe. (addmoretolives.com)
- This study is being done to determine whether or not new blood test(s) can determine the severity of heart conditions. (bioportfolio.com)
- Other testing may confirm the presence of aortic stenosis and help to document its severity. (cincinnatichildrens.org)
- Treatment of mitral stenosis depends on factors that include the patient's symptoms, severity of the stenosis, and health of the patient. (healthcentral.com)
Pulmonary valve44
- The pulmonary valve allows blood to flow out of the heart, into the pulmonary artery and then to the lungs. (heart.org)
- What can be done about the pulmonary valve? (heart.org)
- The pulmonary valve can be treated to improve the obstruction and leak, but the valve can't be made normal. (heart.org)
- In this procedure, a special tool, a catheter containing a balloon, is placed across the pulmonary valve. (heart.org)
- Children who have had pulmonary valve replacement will need to receive antibiotics before certain dental procedures. (heart.org)
- Your cardiologist will examine you regularly to look for problems such as worsening of the obstruction or leakage of the pulmonary valve. (heart.org)
- The pulmonary valve is one of the valves that allow blood from the body to return to the lung for oxygenation. (singhealth.com.sg)
- These valves include the mitral valve, tricuspid valve, pulmonary valve and aortic valve. (chistvincent.com)
- Pulmonary valve stenosis is a heart valve disorder that involves the pulmonary valve. (medlineplus.gov)
- Narrowing of the pulmonary valve is most often present at birth (congenital). (medlineplus.gov)
- Narrowing that occurs in the valve itself is called pulmonary valve stenosis. (medlineplus.gov)
- Pulmonary valve stenosis is a rare disorder. (medlineplus.gov)
- Many cases of pulmonary valve stenosis are mild and do not cause symptoms. (medlineplus.gov)
- You have symptoms of pulmonary valve stenosis. (medlineplus.gov)
- You have been treated or have untreated pulmonary valve stenosis and have developed swelling (of the ankles, legs, or abdomen), difficulty breathing, or other new symptoms. (medlineplus.gov)
- ClinicalTrials.gov lists trials that are related to Pulmonary valve stenosis. (nih.gov)
- PubMed is a searchable database of medical literature and lists journal articles that discuss Pulmonary valve stenosis. (nih.gov)
- Pulmonary valve stenosis is a heart condition affecting the pulmonary valve, the valve that moves the blood from the heart to the lungs, that develops before birth. (mercy.com)
- The condition occurs when the pulmonary valve does not fully open. (mercy.com)
- Most people who are treated for pulmonary valve stenosis have successful outcomes. (mercy.com)
- If left untreated, pulmonary valve stenosis can lead to infectious endocarditis, heart failure, arrhythmia and problems with the heart pumping. (mercy.com)
- Most cases of pulmonary valve stenosis are from congenital heart defects, when the pulmonary valve does not form correctly in the womb. (mercy.com)
- Babies who are born with pulmonary valve stenosis typically are born with other abnormalities. (mercy.com)
- There are few known risk factors of pulmonary valve stenosis if it develops as a congenital heart defect. (mercy.com)
- Some patients with pulmonary valve stenosis do not experience symptoms. (mercy.com)
- Pulmonary valve stenosis is frequently diagnosed in childhood. (mercy.com)
- Based on the blood pressure in the right ventricle and pulmonary artery, pulmonary valve stenosis is classified as mild, moderate or severe. (mercy.com)
- Balloon valvotomy (balloon valvuloplasty) - during this procedure, a balloon is inserted into the pulmonary valve and inflated to widen the pulmonary valve. (mercy.com)
- Pulmonary valve repair or replacement - in severe cases a valve repair or replacement may be necessary. (mercy.com)
- A hypertensive 76-year-old man with severe pulmonary valve stenosis (PVS) and recent initiation of haemodialysis was referred with fever, chills, and asthenia. (hindawi.com)
- A new TTE revealed two pulmonary valve vegetations and a previously undetected ostium secundum-type atrial septal defect (ASD), confirmed by transesophageal echocardiography. (hindawi.com)
- This is a case of pulmonary valve infective endocarditis (IE). (hindawi.com)
- Pulmonary valve IE is extremely rare, especially in structurally normal hearts. (hindawi.com)
- Pulmonary valve replacement in the adult population is an uncommon operation. (bioportfolio.com)
- A 14-year-old female was referred for severe pulmonary valve insufficiency after undergoing radiofrequency ablation for a right ventricular outflow tract tachycardia that originated in the proximal pu. (bioportfolio.com)
- Pulmonary valve restitution following transannular patch repair of tetralogy of Fallot. (bioportfolio.com)
- Chronic pulmonary insufficiency following transannular patch repair of tetralogy of Fallot may mandate restoration of a competent pulmonary valve. (bioportfolio.com)
- Investigation of an anatomically variant isolated bicuspid pulmonary valve: A case report. (bioportfolio.com)
- We provide a discussion of the anatomical characteristics of the bicuspid pulmonary valve (BPV) in this paper. (bioportfolio.com)
- The pathologic narrowing of the orifice of the PULMONARY VALVE. (bioportfolio.com)
- Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. (bioportfolio.com)
- The pulmonary valve sends blood flow to the lungs. (chop.edu)
- Tetralogy of Fallot is a complicated condition that includes several heart defects including a VSD, a large aorta, a small pulmonary valve and thickening or hypertrophy of the right pumping chamber to the lungs. (chop.edu)
- Pulmonary valve stenosis is a problem with a valve in the heart. (denverhealth.org)
Rheumatic fever17
- Rheumatic fever is common worldwide and responsible for many cases of damaged heart valves. (digitalnaturopath.com)
- Rheumatic fever can scar the aortic valve. (webmd.com)
- Tricuspid valve disorders are most commonly a result of rheumatic fever (often associated with untreated strep throat or scarlet fever). (emoryhealthcare.org)
- The main cause of mitral valve stenosis is an infection called rheumatic fever, which is related to strep infections. (mayoclinic.org)
- Rheumatic fever - now rare in the United States, but still common in developing countries - can scar the mitral valve. (mayoclinic.org)
- A complication of strep throat, rheumatic fever can damage the mitral valve. (mayoclinic.org)
- Rheumatic fever is the most common cause of mitral valve stenosis. (mayoclinic.org)
- Although many valve problems develop because of age-related factors, sometimes valve conditions develop due to illnesses, such as rheumatic fever and infective endocarditis . (heart.org)
- Or your aortic valve may have been damaged by rheumatic fever or a heart infection. (kramesonline.com)
- The natural history of mitral stenosis secondary to rheumatic fever (the most common cause) is an asymptomatic latent phase following the initial episode of rheumatic fever. (wikipedia.org)
- These may involve changes in the structure or your valve due to a variety of diseases or infections, including rheumatic fever or endocarditis . (medicinenet.com)
- One cause of mitral valve problems is rheumatic fever , a problem with inflammation that can develop after an infection with Streptococcus bacteria. (seattlechildrens.org)
- Many other valve problems develop due to age-related causes or other diseases such as rheumatic fever and infective endocarditis. (merillife.com)
- If you have had rheumatic fever, see your physician regularly to check for heart problems. (henryford.com)
- Rheumatic fever - develops from untreated strep throat that can damage the heart valves. (mercy.com)
- Calcium build-up in the valve, heart defects at birth and rheumatic fever are some of the causes of aortic stenosis. (addmoretolives.com)
- Rheumatic fever in childhood is by far the most common cause of mitral stenosis in adulthood. (healthcentral.com)
TAVR29
- for the Medtronic TAVR System, a minimally invasive treatment for patients with failing aortic heart valves. (medindia.net)
- The System was designed to increase the potential for optimal device placement during TAVR by providing physicians the option to recapture the valve and reposition it during the procedure as necessary. (medindia.net)
- The trial will enroll low-risk patients from up to 80 clinical sites in the United States with 1:1 randomization to receive the Medtronic TAVR System or undergo open-heart surgery (surgical aortic valve replacement or SAVR). (medindia.net)
- The Medtronic TAVR System replaces a diseased aortic heart valve through a minimally invasive procedure, without open-heart surgery and without surgical removal of the diseased valve. (medindia.net)
- The goal of the trial was to evaluate transcatheter aortic valve replacement (TAVR) with a balloon-expandable valve versus a self-expandable valve among high-risk patients with iliac arteries suitable for transfemoral access. (acc.org)
- Transcatheter aortic valve replacement (TAVR) has emerged as a new option for patients with severe narrowing of the aortic valve and as an effective alternative treatment method to surgical aortic valve replacement in selected high-risk patients. (medindia.net)
- Editorial: Selection of Valves for TAVR - Is the CHOICE Clear? (medindia.net)
- Or you may have a catheter-based procedure (transcatheter aortic valve replacement or TAVR) to replace the valve, even if you don't have symptoms. (kramesonline.com)
- A TAVR procedure uses a catheter to replace the heart valve. (chistvincent.com)
- Whether it's open heart surgery or a TAVR procedure, our experts are here to give you the treatment you deserve. (chistvincent.com)
- In fact, we were one of the first medical centers to perform transcatheter aortic valve replacement (TAVR) - a minimally invasive treatment for severe aortic stenosis. (upmc.com)
- What is a Transcatheter Aortic Valve Implantation (TAVI) or Transcatheter Aortic Valve Replacement (TAVR)? (merillife.com)
- TAVI or TAVR is a minimally aggressive surgical procedure to replace an aortic valve which becomes inefficient due to problems like aortic stenosis. (merillife.com)
- The program is specifically designed to evaluate patients for advanced heart valve treatment, including a new minimally-invasive procedure called transcatheter aortic valve replacement (TAVR). (midmichigan.org)
- TAVR is a procedure that is less invasive than surgery, as the artificial aortic valve is inserted through an artery in the neck, leg or between the ribs, and placed inside the diseased valve while the heart is still beating. (midmichigan.org)
- The Heart Valve Clinic is equipped to determine whether replacement of the aortic valve is necessary, and whether a patient could safely undergo TAVR. (midmichigan.org)
- 56% of heart valve patients identified a shorter hospital stay as a top benefit of minimally-invasive treatment options, such as transcatheter aortic valve replacement (TAVR). (heart-valve-surgery.com)
- While surgical aortic valve replacement (SAVR) has been considered the "gold standard" for aortic valve replacement and a majority (57%) of survey respondents reported receiving SAVR, the less invasive TAVR option has been FDA approved to treat more patients with symptomatic severe aortic stenosis. (heart-valve-surgery.com)
- In 2019, the FDA approved TAVR for patients with aortic stenosis who are at a low risk of surgical mortality, patients who previously would've only been eligible for SAVR. (heart-valve-surgery.com)
- With this step, TAVR is now a treatment option for more aortic stenosis patients than ever before. (heart-valve-surgery.com)
- What Happens to Aortic Valve Debris During TAVR? (heart-valve-surgery.com)
- Transcatheter aortic valve replacement (TAVR) was approved by the FDA last fall for people suffering with severe aortic stenosis who are too frail to undergo traditional open-heart surgery. (rochester.edu)
- UC San Diego Health recently became the first medical center in San Diego to offer transcatheter aortic valve replacement (TAVR) - a new alternative for some patients with aortic valve stenosis. (ucsd.edu)
- The cardiovascular team at Einstein offers compassionate, personalized care using industry-leading technology such as TAVR and MitraClip to treat your heart - and get you back on your feet. (einstein.edu)
- This surgery can be used to replace the aortic (transcatheter aortic valve replacement, or TAVR) or mitral (transcatheter mitral valve replacement, or TMVR) valves, and is sometimes referred to as transcatheter valve-in-valve replacement. (einstein.edu)
- Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure. (dignityhealth.org)
- Today, new minimally invasive procedures like transcatheter aortic valve replacement (TAVR), available at Adventist Health Glendale, are redefining the way aortic stenosis is treated. (adventisthealth.org)
- The TAVR procedure is for people who have severe aortic stenosis and are at intermediate or greater risk for open-heart surgery. (adventisthealth.org)
- All potential TAVR candidates are evaluated by a specially trained TAVR heart team, including two cardiothoracic surgeons and interventional cardiologists. (adventisthealth.org)
Prosthetic14
- This case highlights the pathophysiology of lupus causing stenosis of prosthetic valves and low ejection cardiomyopathy. (hindawi.com)
- Percutaneous heart valve replacement (PHVR) is an emerging, catheter-based technology that allows for implantation of a prosthetic valve without open heart surgery. (annals.org)
- The objective of this study is to assess long term safety and durability of the Advantage prosthetic heart valve. (clinicaltrials.gov)
- If you have a prosthetic (artificial) heart valve. (hse.ie)
- Prosthetic heart valves are increasingly being used to treat a range of heart conditions, such as stenosis (where one of the valves of the heart narrows). (hse.ie)
- Currently, adults who undergo replacement of diseased valves by either mechanical prosthetic or tissue valves (including bioprosthetic valves [porcine aortic valve or bovine pericardial xenograft], cadaveric allograft, or pulmonary-to-aortic autograft valves [Ross procedure]) generally have enhanced survival and quality of life. (springer.com)
- For both conditions, the most definitive treatment involves surgical replacement of the valve with a prosthetic valve. (hopkinsmedicine.org)
- The resulting valve ring or annulus is then measured to select the size of the valve prosthetic. (hopkinsmedicine.org)
- A series of sutures are then placed around the valve annulus and subsequently through the prosthetic valve. (hopkinsmedicine.org)
- Mechanical prosthetic valves have lifelong durability, however a blood thinning drug known as coumadin or warfarin must be taken for the rest of the patient's life to prevent blood clots from forming on the hinges of the valve. (hopkinsmedicine.org)
- To solve this problem, a team of scientists from Boston Children's Hospital developed a prosthetic valve that mimics the geometry of the human venous valve. (news-medical.net)
- For the first time, the new valve, a biomimetic prosthetic valve, adapts to accommodate growth and structural asymmetries within the heart. (news-medical.net)
- The team tested the prosthetic heart valve in growing young lambs. (news-medical.net)
- The researchers also found that the new prosthetic valve promotes favorable blood flow through the valve, reducing the risk for blood clot formation, which is often observed in existing valve replacement devices. (news-medical.net)
Flaps15
- A normal aortic valve has three flaps, or cusps, that fit snugly together. (webmd.com)
- It can damage the mitral valve by causing the flaps to thicken or fuse. (mayoclinic.org)
- Your heart valves have flaps that open and close with each heartbeat, allowing blood to flow through the heart's upper and lower chambers and to the rest of your body. (healthline.com)
- These valves have tissue flaps that open and close with each heartbeat. (gopetsamerica.com)
- In a normal heart, when the left ventricle squeezes, blood flows out of it and the flaps of the aortic valve open to allow blood to flow through. (upmc.com)
- When the heart relaxes, the flaps of the valve snap shut to prevent blood from flowing backward. (upmc.com)
- Mitral valve prolapse is when 1 or both valve flaps don't close smoothly and may not seal tightly when the heart pumps. (seattlechildrens.org)
- Aortic stenosis mainly affects older people as a result of scarring and calcium buildup in the valve flaps. (merillife.com)
- A stenosis, or narrowing, of the valve occurs when the valve's flaps become thick and stiff, preventing the valve from fully opening. (henryford.com)
- Heart valves are four sets of flaps that control the direction that blood pumps around the heart. (hse.ie)
- Think of a valve as a doorway with three flaps that open and snap shut to allow blood to flow into the heart, through the chambers and out to the body. (einstein.edu)
- The mitral valve, located between the heart's left upper and lower chambers, has two flaps. (upmc.com)
- These flaps open and close to control the flow of blood through your heart. (upmc.com)
- In previous heart valve models, they contain three leaflet-like flaps providing a one-way inlet or outlet for blood flow. (news-medical.net)
- However, in the new heart valve, it only has two flaps, with a geometry designed to maintain closure, and a one-way flow even when the veins expand in diameter. (news-medical.net)
Minimally16
- We use minimally invasive techniques whenever we can and are committed to repairing a child's own valve rather than resorting to an entire valve replacement whenever possible. (childrenshospital.org)
- Some people who cannot have open-heart surgery may have a minimally invasive procedure to replace the valve. (webmd.com)
- Surgical treatment options available to you include open heart surgery and minimally invasive aortic valve replacement. (chistvincent.com)
- Cardiac catheterization is a minimally invasive way to diagnose and treat a variety of heart and vascular conditions by guiding thin, flexible tubes called catheters through blood vessels to problem areas. (medstarheartinstitute.org)
- Tricuspid valve surgery includes repair or replacement of a damaged valve using traditional or minimally invasive methods. (medstarheartinstitute.org)
- Minimally invasive valve surgery is done through much smaller cuts than open surgery, or through a catheter inserted through the skin. (medlineplus.gov)
- At the UPMC Heart and Vascular Institute , we offer the full range of treatments for aortic stenosis including surgical and minimally invasive valve replacement. (upmc.com)
- Amidst the current COVID-19 environment, minimally-invasive treatment options are available to many patients who are determined by heart teams to be suitable candidates. (heart-valve-surgery.com)
- We use the most advanced treatments available, including minimally invasive valve procedures, to help you enjoy an active, healthy life. (henryford.com)
- In patients who may not be appropriate candidates for traditional or minimally invasive valve surgeries, percutaneous options allow a replacement valve to be delivered and placed through a catheter that is threaded through blood vessels rather than performing open heart surgery. (ucsd.edu)
- This minimally invasive procedure allows us to repair a valve without removing it. (ucsd.edu)
- In some cases, we may be able to use minimally invasive techniques to restore valve function. (einstein.edu)
- The doctors at Dignity Health - St. Rose Dominican usually treat severe aortic valve stenosis by replacing the valve through open heart surgery or a minimally invasive procedure. (dignityhealth.org)
- A minimally invasive surgery or a catheter procedure to replace the aortic valve may be an option for some people. (childrensheartinstitute.org)
- The study attributes medical professionals' preferences as well as patients' choice deviating from standard valve replacement procedures towards the ones that involve minimally invasive surgical techniques for the increasing need for TAVI in the heart valve repair and replacement market. (marketresearchblog.org)
- This innovative research allows us to provide the latest treatments - such as the MitraClip ® - as well as minimally invasive mitral valve techniques. (upmc.com)
Tricuspid valve st2
- In tricuspid valve stenosis, the valve narrows, increasing pressure in the right atrium and decreasing blood flow to the lungs. (emoryhealthcare.org)
- Tricuspid valve stenosis itself usually doesn't require treatment. (wikipedia.org)
Leaky5
- As the leak worsens, the heart has to work harder to make up for the leaky valve, and less blood may flow to the rest of the body. (medicinenet.com)
- Without the third leaflet, the valve may be stiff (unable to open or close properly) or leaky (not able close tightly). (medicinenet.com)
- This can lead to leaky valves. (medicinenet.com)
- Children born with bicuspid aortic valve or congenitally deformed valve which may go unnoticed during development, may not cause problems until adulthood at which point the aortic valve may get tight and/or leaky. (upmc.com)
- This condition is also known as 'leaky valve' and occurs when the heart valve does not close properly. (healthwatchcenter.com)
Lungs18
- Normally the right side of the heart pumps blood to the lungs. (heart.org)
- Pulmonary stenosis is a narrowing of the valve that lets blood flow from the lower-right chamber (the right ventricle) into the lungs. (texasheart.org)
- This can cause blood to back up elsewhere in the heart, and even back into the lungs . (webmd.com)
- In mitral valve stenosis, pressure that builds up in the heart is then sent back to the lungs, resulting in fluid buildup (congestion) and shortness of breath. (mayoclinic.org)
- Abnormality in the mitral valve, for example, affects blood flow to the lungs because it located on the left side of the heart, while the tricuspid valve, found on the right side of the heart, affects blood flow to the rest of the body. (petmd.com)
- Pulmonary capillary pressures in this level cause an imbalance between the hydrostatic pressure and the oncotic pressure, leading to extravasation of fluid from the vascular tree and pooling of fluid in the lungs (congestive heart failure causing pulmonary edema). (wikipedia.org)
- Chest X-rays use a small dose of radiation to create pictures of the structures inside the chest, including the lungs, heart and chest wall. (medstarheartinstitute.org)
- This pattern is repeated over and over, causing blood to flow continuously to the heart, lungs and body. (medicinenet.com)
- The pulmonary (or pulmonic) valve lies between the right ventricle (lower heart chamber) and the pulmonary artery, which sends blood to the lungs to pick up oxygen to deliver to the body. (henryford.com)
- The narrowed opening prevents blood from flowing forward through the heart to the lungs. (henryford.com)
- Although some blood flows forward into the lungs, the blood that leaks backward can build up in the heart. (henryford.com)
- Two other valves control blood flow from the ventricles, one to the lungs and the other to the rest of the body. (blausen.com)
- This procedure allows for the heart to pump more effectively, reducing pressure in the heart and lungs. (blausen.com)
- Once back in the heart, the blood flows along to the lungs, where it disposes of carbon dioxide and restocks its supply of oxygen before cycling through your body once more. (healthcentral.com)
- In this approach, the surgery is performed through a small incision, providing access to the heart and lungs for surgical procedures such as aortic valve replacements, and mitral valve repairs and replacements. (ucsd.edu)
- Cardiopulmonary bypass serves as a temporary substitute for a patient's heart and lungs during the course of open-heart surgery . (britannica.com)
- With this machine the blood bypasses the heart and lungs so that the surgeon has an unobstructed view of the operative field. (britannica.com)
- In this manner, oxygen is introduced into the blood, and carbon dioxide is removed in sufficient quantities to make the blood leaving the oxygenator similar to that normally returning to the heart from the lungs. (britannica.com)
Abnormal16
- The term stenosis means an abnormal narrowing of an opening. (digitalnaturopath.com)
- It can also lead to an abnormal heart rhythm (atrial fibrillation), which further decreases the efficiency of the pumping action of the heart. (digitalnaturopath.com)
- Drug therapy may help to slow the heart rate, strengthen the heart beat, and control abnormal heart rhythm. (digitalnaturopath.com)
- But as you move into adulthood, the abnormal valve is more likely to get stiffer and not open as well. (webmd.com)
- Being born with an abnormal aortic valve means you may have aortic valve stenosis later in life. (webmd.com)
- This abnormal valve doesn't open properly, blocking blood flow coming into your left ventricle, the main pumping chamber of your heart. (mayoclinic.org)
- Diseased, abnormal or irregularly shaped vessels leading to the heart. (newheartvalve.com)
- The term "stenosis" describes an abnormal narrowing within a structure of the body. (childrenshospital.org)
- X-rays can help your veterinarian to determine if there is enlargement of the valves or atrium on either side of the heart, and echocardiography will show atrial dilation, and possibly abnormal flow of the blood through the heart, in the case of tricuspid valve dysplasia. (petmd.com)
- An abnormal rhythm, and the exact measurement of the abnormality can be a great help in determining which side of the heart is most affected. (petmd.com)
- In some cases, you may have been born with an abnormal aortic valve. (kramesonline.com)
- While listening to your heart with a stethoscope, your primary care doctor can detect the condition by hearing abnormal valve sounds called murmurs. (upmc.com)
- We have extensive experience with the treatment these patients may require, including cardiac catheterization and surgery to repair or replace abnormal mitral valves. (seattlechildrens.org)
- Abnormal chromosomes increase the incidence of congenital heart defects. (encyclopedia.com)
- During exercise patients with important degrees of aortic stenosis may show abnormal blood pressure responses or electrocardiogram changes. (cincinnatichildrens.org)
- In more severe cases, children may require a cardiac catheterization and balloon dilation of the abnormal valve. (chop.edu)
Atrial8
- Play media Signs and symptoms of mitral stenosis include the following: Heart failure symptoms, such as dyspnea on exertion, orthopnea and paroxysmal nocturnal dyspnea (PND) Palpitations Chest pain Hemoptysis Thromboembolism in later stages when the left atrial volume is increased (i.e., dilation). (wikipedia.org)
- citation needed] When the mitral valve area goes less than 1 cm2, there will be an increase in the left atrial pressures (required to push blood through the stenotic valve). (wikipedia.org)
- Since the normal left ventricular diastolic pressures is about 5 mmHg, a pressure gradient across the mitral valve of 20 mmHg due to severe mitral stenosis will cause a left atrial pressure of about 25 mmHg. (wikipedia.org)
- citation needed] In individuals with severe mitral stenosis, the left ventricular filling is dependent on the atrial kick. (wikipedia.org)
- The loss of the atrial kick due to atrial fibrillation ( i.e. blood cannot flow into the left ventricle thus accumulating in the left atrium ) can cause a precipitous decrease in cardiac output and sudden congestive heart failure. (wikipedia.org)
- Furthermore, surrogate outcomes are ejection fraction, hypertrophy, long axis ventricular function, torsion, left atrial indices, pressures in the left sided heart and in the pulmonary circulation as well as a number of other echocardiographic parameters. (uantwerpen.be)
- Medications may also be used to treat the complications of aortic stenosis, such as congestive heart failure or atrial fibrillation . (freemd.com)
- A patient can also develop atrial fibrillation (an irregular heart beat). (healthcentral.com)
Bicuspid aorti3
- Typically the aortic valve has three cusps (tricuspid aortic valve), but some people are born with an aortic valve that has two cusps (bicuspid aortic valve). (mayoclinic.org)
- Although some people have AS due to a congenital heart defect called a bicuspid aortic valve, this condition more commonly develops during aging, due to calcium deposition or scarring, which damages the valve and reduces the amount of blood flow. (merillife.com)
- This is called a bicuspid aortic valve (or BAV). (cincinnatichildrens.org)
Complications6
- Left untreated, mitral valve stenosis can lead to serious heart complications. (mayoclinic.org)
- Often considered asymptomatic, their progression can lead to further complications and it is often associated with heart failure. (withings.com)
- The long-term safety of the valve will be assessed by the rate of valve related complications. (clinicaltrials.gov)
- Results of the PARTNER (Placement of AoRTic TraNscathetER Valve) trial indicate some complications from surgery include stroke and vascular problems, such as aortic dissection or perforation. (rochester.edu)
- Congestive heart failure is one of the complications which can appear, even years after the operation. (uantwerpen.be)
- With the invasive heart valve device, there are fewer complications that may endanger the life of the child. (news-medical.net)
Narrows6
- When this valve narrows, the right ventricle has to work harder and it becomes enlarged. (texasheart.org)
- After valve surgery or balloon valvuloplasty, the valve sometimes narrows again, so people with pulmonary stenosis should see their doctor regularly. (texasheart.org)
- When the valve narrows, it does not open or close properly, making the heart work harder to pump blood throughout the body. (medindia.net)
- In aortic stenosis, the valve narrows, restricting blood flow from the heart. (emoryhealthcare.org)
- This form happens when the heart's aortic valve narrows, which hinders the flow of blood to the body. (withings.com)
- Aortic stenosis occurs when the aortic valve narrows. (upmc.com)
Cardiac20
- If surgery is necessary, cardiac catheterization may be done to fully evaluate the heart before the operation. (digitalnaturopath.com)
- We will focus only on drugs believed to prevent clinical, cardiac functional, or valve abnormalities or to delay surgery and will avoid discussion of anticoagulants and specific antiarrhythmics that might be appropriate in certain settings. (ahajournals.org)
- As in all cardiac diseases, clinical manifestations in AS result from the combined mechanical effects of the structural valve abnormality and the myocardial response to the resulting mechanical stresses. (ahajournals.org)
- In normal cardiac physiology, the mitral valve opens during left ventricular diastole, to allow blood to flow from the left atrium to the left ventricle. (wikipedia.org)
- This gradient may be increased by increases in the heart rate or cardiac output. (wikipedia.org)
- With aortic stenosis, your risk for heart failure and sudden cardiac death becomes greater. (chistvincent.com)
- Magnetic resonance imaging, better known as cardiac MRI, is a combination of radio waves, magnets and computer technology to create images of your heart and blood vessels. (medstarheartinstitute.org)
- Cardiac catheterization, which enables your doctor to see blood flow through the heart and its arteries. (upmc.com)
- We also have a pediatric cardiac anesthesia team and a Cardiac Intensive Care Unit to help care for children who have heart surgery. (seattlechildrens.org)
- Quadricuspid aortic valve is a rare congenital condition that occurs not only as an isolated anomaly, but also with other cardiac defects. (biomedsearch.com)
- This new FDA-approved, less invasive heart valve replacement procedure is one more tool in caring for people too ill for open-heart surgery," said George L. Hicks, M.D ., chief of Cardiac Surgery . (rochester.edu)
- Patients who attend our Valve Clinic are seen by a team of physicians and health care providers, including cardiologists and cardiac surgeons. (ucsd.edu)
- Our surgeons use the da Vinci robot to help address mitral and tricuspid valve disorders, cardiac tumors, some congenital defects and select coronary bypass procedures. (ucsd.edu)
- The following recommendations are preventive measures recommended by other fire service groups to reduce the risk of on-the-job heart attacks and sudden cardiac arrest among fire fighters. (cdc.gov)
- In fact this condition of the heart valve may result in other complex cardiac conditions which have to be treated by an experienced heart specialist. (healthwatchcenter.com)
- These sounds can be detected through careful examination of the heart by a physician well-trained in cardiac diagnosis. (cincinnatichildrens.org)
- The Children's Hospital of Philadelphia is a proven leader in cardiac care and heart surgery. (chop.edu)
- Specialists at the Cardiac Center are experts at diagnosing and treating every congenital heart condition. (chop.edu)
- The first heart-lung machine (pump oxygenator) resembled only slightly the complicated apparatus currently used for correction of cardiac defects. (britannica.com)
- Aikawa E, Whittaker P, Farber M, Mendelson K, Padera RF, Aikawa M, Schoen FJ (2006) Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. (springer.com)
Surgery73
- If a child is cyanotic (bluish), the valve must be widened right away, either through open heart valve surgery or balloon valvuloplasty. (texasheart.org)
- To date, the technology is commercially approved only for patients with severe aortic stenosis who are considered at high or extreme risk for surgery. (medindia.net)
- This new study will enable us to determine whether this treatment will be a viable alternative to open heart surgery for a broader patient population," according to Dr. Davis. (medindia.net)
- The Medtronic family of Valves and Delivery Catheter System were FDA-approved for commercial use in the United States for severe aortic stenosis patients who are at high or extreme risk for surgery. (medindia.net)
- If aortic valve stenosis happens along with other heart problems, such as other valve problems, it can affect the decision of when to have surgery to replace the valve. (lancastergeneralhealth.org)
- Your doctor might suggest a surgery to repair or replace the mitral valve and replace the aortic valve at the same time. (lancastergeneralhealth.org)
- But it is more risky to have multiple-valve surgery than to replace a single valve. (lancastergeneralhealth.org)
- Damage to the muscle from the heart attack also can increase the risk of valve surgery. (lancastergeneralhealth.org)
- Treatment involves surgery to repair or replace the mitral valve. (healthline.com)
- Most people are able to have their aortic valve repaired successfully with surgery. (healthline.com)
- According to the Cleveland Clinic , 80 percent of people with this type of heart valve disorder will require surgery to repair or replace the valve. (healthline.com)
- Other people may need surgery to replace or repair the valve. (healthline.com)
- However, children with more advanced aortic valve stenosis are likely to require interventional catheterization, valve repair or replacement surgery. (childrenshospital.org)
- Interventional catheterization with balloon dilation or valve repair or replacement surgery are necessary to treat severe aortic valve stenosis. (childrenshospital.org)
- Different from surgery, transcatheter placement (via the patient's groin) of aortic valve prostheses requires either a self-expandable or balloon-expandable system. (medindia.net)
- If the stenosis is severe, your doctor may recommend surgery to replace the valve, even if you don't have symptoms. (kramesonline.com)
- If the stenosis is severe, your healthcare provider may advise surgery to replace the valve. (kramesonline.com)
- You probably will not have surgery until your stenosis is severe or until the benefits of surgery outweigh the risks. (webmd.com)
- Valve replacement is typically done during open-heart surgery. (webmd.com)
- Denver Broncos coach John Fox had heart surgery Saturday and Houston Texans coach Gary Kubiak collapsed Sunday night after having a transient ischemic attack, also known as a mini-stroke or a TIA. (heart.org)
- citation needed] In individuals having been offered mitral valve surgery but refused, survival with medical therapy alone was 44 ± 6% at 5 years, and 32 ± 8% at 10 years after they were offered correction. (wikipedia.org)
- Surgery can repair or replace valves in severe cases. (chistvincent.com)
- Heart valve surgery is used to repair or replace diseased heart valves. (medlineplus.gov)
- This is called valve replacement surgery. (medlineplus.gov)
- You may need surgery if your valve does not work properly. (medlineplus.gov)
- Your doctor wants to replace or repair your heart valve at the same time as you are having open heart surgery for another reason, such as a coronary artery bypass graft surgery. (medlineplus.gov)
- The patient underwent elective valve replacement with a mechanical prosthesis, and during surgery, the valve was noted to be quadricuspid. (biomedsearch.com)
- Aortic valve replacement (AVR) through open heart surgery, in which surgeons replace the diseased aortic valve with an artificial valve, is the most common method. (midmichigan.org)
- A new survey reveals that 80% of patients are 'extremely satisfied' after heart valve surgery. (heart-valve-surgery.com)
- 89% of patient respondents had heart valve surgery. (heart-valve-surgery.com)
- U.S. News & World Report consistently ranks Seattle Children's cardiology and heart surgery program as one of the best in the country. (seattlechildrens.org)
- His Cardiologist said that he was going to have to have open heart surgery to repair it. (heart-valve-surgery.com)
- Adam Pick is a heart valve patient and author of The Patient's Guide To Heart Valve Surgery . (heart-valve-surgery.com)
- Purpose: To evaluate the safety and efficacy of THV-9300 for patients who have severe symptomatic aortic stenosis attributed to calcification and degeneration of a valve leaflet and for whom undergoing a surgery safely would be difficult. (clinicaltrials.gov)
- Mitral valve replacement, an open heart surgery, is performed when the mitral valve is too damaged to be repaired. (medwonders.com)
- A sizer measures a valve annulus to determine a size of an artificial heart valve to be sewn in the valve annulus during heart-valve replacement surgery. (google.com)
- Just under half of all people with endocarditis will require surgery to repair the damage to their heart. (hse.ie)
- I will be needing surgery to replace my mitral stenosis. (steadyhealth.com)
- The treatment is usually by surgery (tricuspid valve replacement ) or percutaneous balloon valvuloplasty . (wikipedia.org)
- A single center retrospective analytical study of all patients aged 50-65 years with severe aortic stenosis who underwent surgery between 2000 and 2015 was performed ( n = 200). (elsevier.es)
- Timely surgery is advised since significant delay can lead to irreversible congestive heart failure. (hopkinsmedicine.org)
- Einstein Healthcare Network's heart surgery team is among the area's most experienced with heart valve conditions. (einstein.edu)
- In other cases, your surgeon may recommend open heart surgery. (einstein.edu)
- Open heart surgery involves a large incision in the chest and through the breastbone to gain access to the heart and exchange the diseased valve with a new valve. (dignityhealth.org)
- MAYWOOD, Ill. - Loyola University Medical Center has implanted its 100th patient with a new artificial aortic heart valve that does not require open-heart surgery. (eurekalert.org)
- The study found that patients who received the device had significantly lower mortality than heart-valve patients who underwent open-heart surgery. (eurekalert.org)
- Heart surgery for congenital defects is performed to repair a defect, providing improved blood flow to the pulmonary and systemic circulations and better oxygen delivery to the body. (encyclopedia.com)
- Surgery is recommended for congenital heart defects that result in a lack of oxygen, a poor quality of life, or when a patient fails to thrive. (encyclopedia.com)
- It is expected that catheterization procedures will continue to replace more types of surgery for congenital heart defects in the future. (encyclopedia.com)
- During this surgery, the damaged valve is removed and replaced with an artificial valve. (childrensheartinstitute.org)
- During open-heart valve surgery, the doctor makes a large incision in the chest. (childrensheartinstitute.org)
- The heart may be cooled to slow or stop the heartbeat so that the heart is protected from damage while surgery is done to replace the valve with an artificial valve. (childrensheartinstitute.org)
- Valve replacement surgery is an effective treatment for people who have severe aortic valve stenosis. (childrensheartinstitute.org)
- footnote 2 If you don't have surgery after your stenosis is severe, you may die suddenly or develop heart failure. (childrensheartinstitute.org)
- Valve replacement surgery has a high rate of success and a low risk of causing other problems if you are otherwise healthy. (childrensheartinstitute.org)
- Valve replacement surgery is high-risk for people who have a failing left ventricle and who have had a heart attack. (childrensheartinstitute.org)
- About 5 or less out of 100 people who have valve surgery die. (childrensheartinstitute.org)
- This will depend on the type of valve you get and how long you live after you have the surgery. (childrensheartinstitute.org)
- In the PARTNER trial, 358 patients unsuitable for surgery were randomised to either transcatheter valve implantation or standard care, including balloon valvuloplasty. (chilternhillsheartclinic.com)
- The PARTNER investigators explain that "On the basis of a rate of death from any cause at one year that was 20 percentage points lower with TAVI than with standard therapy, balloon-expandable TAVI should be the new standard of care for patients with aortic stenosis who are not suitable candidates for surgery," the PARTNER authors conclude. (chilternhillsheartclinic.com)
- The EVEREST II study was designed to evaluate the safety and effectiveness of the MitraClip" procedure in comparison with open-chest mitral valve surgery in 279 patients. (chilternhillsheartclinic.com)
- This is an emergency situation that requires immediate treatment, either balloon dilation of the valve or surgery. (cincinnatichildrens.org)
- Depending on the situation, the doctor may recommend open-heart surgery to repair or replace the valve, or the doctor may recommend a procedure to repair the valve that does not require open-heart surgery. (freemd.com)
- Medications may be used to treat aortic stenosis in someone who has symptoms, but surgery offers the only chance for a cure. (freemd.com)
- For decades, the gold standard of treatment for people with severe aortic stenosis, or narrowing of the aortic valve opening in the heart, was an extensive and risky open-heart surgery. (adventisthealth.org)
- Because the procedure is less invasive than open-heart surgery, patients experience faster relief of symptoms, shorter hospital stays and a quicker return to normal activities. (adventisthealth.org)
- In all cases of TOF, open heart surgery will be required in the first few months of life. (chop.edu)
- Whether your condition requires medication, mitral valve repair, or complete valvular replacement surgery, UPMC vascular surgeons provide you with the best type of treatment. (upmc.com)
- More severe stenosis may need surgery. (denverhealth.org)
- Surgery may repair or replace the bad valve. (denverhealth.org)
- Open heart surgery-To repair valves that cannot be opened with less invasive options. (denverhealth.org)
- The doctors can use keyhole surgery to insert a rubber tube attached to a deflated balloon in the valve. (news-medical.net)
- In some cases, the valve may need to be replaced in another type of open heart surgery. (healthcentral.com)
Valvular stenosis4
- Valvular stenosis occurs when a valve isn't able to open completely, which means that not enough blood can flow through the valve. (healthline.com)
- Some people don't need treatment for valvular stenosis. (healthline.com)
- Valvular Stenosis is the second type of the heart valve problem. (healthwatchcenter.com)
- Valvular Stenosis makes the heart work very hard to pump blood into the arteries and this extra effort may lead to heart attack or heart failure as well. (healthwatchcenter.com)
Congenital heart2
- This type of congenital heart defect can be treated by repairing or replacing the valve. (webmd.com)
- Specific to trisomy 21 (Down syndrome), 23 - 56% of infants have a congenital heart defect. (encyclopedia.com)
Balloon valvuloplasty8
- In some cases the valve cannot be treated by balloon valvuloplasty. (heart.org)
- In balloon valvuloplasty, a balloon is guided into the heart on the tip of a long, thin tube called a catheter, then inflated to force the valve to open wider. (texasheart.org)
- Some young people or pregnant women may have another procedure called balloon valvuloplasty to enlarge the valve opening. (webmd.com)
- A 38-year-old male with previous surgeries for an incomplete atrioventricular septal defect successfully underwent percutaneous transcatheter tricuspid balloon valvuloplasty for a deteriorated bioprosthetic valve. (clinmedjournals.org)
- Percutaneous techniques enable balloon valvuloplasty to treat mitral valve stenosis and also allow replacement of the aortic valve in high-risk patients with critical aortic stenosis (narrowing of the aortic valve opening). (ucsd.edu)
- Balloon valvuloplasty: a catheter is inserted into an artery in the groin or arm, and a balloon at eh end of the catheter is used to open the narrowed passageway through the valve. (freemd.com)
- Balloon valvuloplasty -A balloon will be passed to the valve and gently inflated. (denverhealth.org)
- Percutaneous balloon valvuloplasty (percutaneous means 'through the skin' [with a catheter], valvulo means 'related to the valve,' plasty means 'shaping'), is a procedure in which one or two balloons mounted on catheters are guided into the heart through blood vessels in the groin, positioned through the stenotic valve, and then inflated. (healthcentral.com)
Narrowing of the heart's1
- Mitral valve stenosis - or mitral stenosis - is a narrowing of the heart's mitral valve. (mayoclinic.org)
Known as mitral valve st1
- This condition is known as mitral valve stenosis. (blausen.com)
Patients with severe7
- A randomized controlled multicenter study comparing the acute hemodynamic performance of the Edwards Sapien XT and the Medtronic CoreValve transcatheter heart valves in high risk patients with severe symptomatic aortic stenosis. (clinicaltrials.gov)
- The investigational device exemption (IDE) trial will include 1,256 patients with severe aortic stenosis who have a less than 3 percent risk of mortality, as determined by a heart team. (medindia.net)
- Without an aortic valve replacement, 50% of patients with severe aortic stenosis do not survive 2 years after the onset of symptoms. (heart-valve-surgery.com)
- Objectives We analyzed the clinical characteristics and outcomes of 47 patients with severe pulmonary hypertension (PHT) and severe aortic valve stenosis (AS) from 1987 to 1999. (onlinejacc.org)
- Severe pulmonary hypertension (PHT) in patients with severe aortic valve stenosis (AS) is not uncommon, with a reported prevalence as high as 29% among patients having an invasive hemodynamic study before aortic valve replacement (AVR) (1) . (onlinejacc.org)
- Detection of more subtle changes, even in asymptomatic patients with severe aortic valve stenosis should lead to early replacement. (uantwerpen.be)
- Thereby, with the rise in the prevalence and incidence of aortic stenosis along with the patients' tendency to prefer noninvasive medical procedures is contributing to the rise in the adoption of TAVI among intermediate risk patients with severe aortic stenosis. (marketresearchblog.org)
Shortness6
- The first symptoms of heart failure, which are fatigue and shortness of breath , usually appear only during physical activity. (digitalnaturopath.com)
- Call your doctor for an immediate appointment if you develop fatigue or shortness of breath during physical activity, heart palpitations, or chest pain. (mayoclinic.org)
- Defects in your heart valve are causing major heart symptoms, such as chest pain ( angina ), shortness of breath, fainting spells (syncope), or heart failure. (medlineplus.gov)
- Signs and symptoms of severe AS can include chest pain or tightness, feeling faint or fainting with activity, dizziness, fatigue, shortness of breath, irregular heart beat or an unusual sound during a heartbeat. (midmichigan.org)
- Patients struggling with aortic stenosis can experience several different types of symptoms including shortness of breath, fatigue, difficulty when exercising dizziness, fainting and swollen ankles. (heart-valve-surgery.com)
- Symptoms of mitral valve stenosis include shortness of breath with effort or when lying flat, exhaustion, and palpitations. (healthcentral.com)
Heart's aortic valve1
- The device is used to treat aortic stenosis, which occurs when the heart's aortic valve is narrowed, restricting blood from the heart to the body. (eurekalert.org)
Artificial Heart4
- The resilient member is disposed about the support member and has a resiliency substantially equal to the resiliency of a sewing ring of the artificial heart valve. (google.com)
- said resilient member having a resiliency substantially the same as the resiliency of the sewing ring of the artificial heart valve. (google.com)
- 5. A sizer as claimed in claim 1 wherein said resilient member is configured substantially the same as the sewing ring of the artificial heart valve. (google.com)
- However, children grow, and the artificial heart valve may not be able to accommodate the heart's increasing size. (news-medical.net)
Diagnosis4
- Brochure for primary care physicians, containing a brief summary of aortic stenosis prevalence, diagnosis, treatment options and current data. (newheartvalve.com)
- To be sure of the diagnosis, your doctor may want you to have an echocardiogram , which can show moving pictures of your heart. (webmd.com)
- Your UPMC heart and vascular specialist may recommend tests to confirm the diagnosis, as well as to diagnose other conditions such as heart rhythm problems or atherosclerosis . (upmc.com)
- Now, more than ever, early diagnosis and treatment for aortic stenosis is important as the condition can be deadly if put off for too long. (heart-valve-surgery.com)
Mitral and tricuspid5
- It fills with blood and then pumps it out thanks to four valves that open and close with every heartbeat: Aortic, pulmonary, mitral and tricuspid. (withings.com)
- Valve repair is best for the mitral and tricuspid valves. (medlineplus.gov)
- Blood flows from your right and left atria into your ventricles through the open mitral and tricuspid valves. (medicinenet.com)
- When the ventricles are full, the mitral and tricuspid valves shut. (medicinenet.com)
- The mitral and tricuspid valves control blood flow between the atria (upper chambers) and the ventricles (lower chambers). (einstein.edu)
Occurs12
- It occurs when the mitral valve doesn't close properly, sometimes causing blood to flow back into the left atrium. (healthline.com)
- It occurs when any of the heart valves doesn't close properly, causing blood to flow backward. (healthline.com)
- Congenital Mitral Valve Stenosis occurs infrequently in dogs often in association with subaortic stenosis. (gopetsamerica.com)
- The initial infection usually occurs in children, but the heart problems associated with the infection may not be seen until 20-40 years later. (medicinenet.com)
- Endocarditis occurs when germs, especially bacteria, enter the bloodstream and attack the heart valves, causing growths and holes in the valves and scarring. (medicinenet.com)
- Stenosis, or narrowing, occurs when the valve cannot open wide enough. (medlineplus.gov)
- When this occurs, it forces the heart to work harder to pump blood through the valve. (rochester.edu)
- Endocarditis is a potentially serious condition because the inflammation (swelling) that occurs inside the heart can interrupt the normal blood flow through the heart valves. (hse.ie)
- Results: It has become clear that decrease in ejection fraction, which is the most commonly used parameter, occurs late in the course of aortic valve stenosis, when damage to the left ventricle has already been inflicted. (uantwerpen.be)
- If this occurs it is almost always in a newborn infant with very severe valve obstruction. (cincinnatichildrens.org)
- Heart failure rarely occurs later in childhood. (cincinnatichildrens.org)
- Infection on the valve, or endocarditis, occurs secondary to bacteria entering the blood stream and attaching themselves to the mitral valve. (upmc.com)
Left ventricular4
- The high prevalence of side effects is a serious concern because patients with aortic stenosis and left ventricular dysfunction represent a high-risk group. (ahajournals.org)
- Conclusions: Damage to the left ventricle in patients with aortic valve stenosis can go unnoticed if ejection fraction is used as sole determinant of left ventricular function, for the timing of operation. (uantwerpen.be)
- When the aortic valve is severely obstructed, the left ventricular muscle may not be able to compensate satisfactorily. (cincinnatichildrens.org)
- With severe aortic stenosis, the electrocardiogram can show enlargement of the left ventricle and may even show evidence of left ventricular strain. (cincinnatichildrens.org)
Aortic valves1
- Once the ventricles have filled with blood, they begin to contract, forcing the pulmonary and aortic valves to open. (healthline.com)
Treatments3
- There may be an increased risk of stroke in transcatheter aortic valve replacement procedures, compared to other standard treatments for aortic stenosis in the high or greater risk population. (newheartvalve.com)
- What treatments are advisable for people with aortic stenosis? (merillife.com)
- Possible treatments may include valve repair or valve replacement. (merillife.com)
Transcatheter Aortic Valve Implantation1
- To observe the clinical outcomes of the different valve sizing strategies treating type-0 Bicuspid Aortic Stenosis (BAS) with self-expandable transcatheter aortic valve implantation (TAVI). (bioportfolio.com)