A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
The minimum acceptable patient care, based on statutes, court decisions, policies, or professional guidelines.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Elements of limited time intervals, contributing to particular results or situations.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Sequential operating programs and data which instruct the functioning of a digital computer.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Application of statistical procedures to analyze specific observed or assumed facts from a particular study.
Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
An infant during the first month after birth.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Computer-based representation of physical systems and phenomena such as chemical processes.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
Substances that reduce the growth or reproduction of BACTERIA.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A series of steps taken in order to conduct research.
Chromatographic techniques in which the mobile phase is a liquid.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Facilities equipped to carry out investigative procedures.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Therapy with two or more separate preparations given for a combined effect.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
Techniques used in studying bacteria.
The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)
Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, or during a 24-hour period in the general population, which does not appear to cause appreciable harm, whether immediate or delayed for any period, in the target population. (From Lewis Dictionary of Toxicology, 1st ed)
Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
The return of a sign, symptom, or disease after a remission.
Organized activities related to the storage, location, search, and retrieval of information.
Tumors or cancer of the human BREAST.
The giving of drugs, chemicals, or other substances by mouth.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
Method of measuring and mapping the scope of vision, from central to peripheral of each eye.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.
Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
The portion of an interactive computer program that issues messages to and receives commands from a user.
An American National Standards Institute-accredited organization working on specifications to support development and advancement of clinical and administrative standards for healthcare.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The study of chance processes or the relative frequency characterizing a chance process.
The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.
A specified list of terms with a fixed and unalterable meaning, and from which a selection is made when CATALOGING; ABSTRACTING AND INDEXING; or searching BOOKS; JOURNALS AS TOPIC; and other documents. The control is intended to avoid the scattering of related subjects under different headings (SUBJECT HEADINGS). The list may be altered or extended only by the publisher or issuing agency. (From Harrod's Librarians' Glossary, 7th ed, p163)
Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine.
Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.
Data processing largely performed by automatic means.
A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Societies whose membership is limited to physicians.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record.
An office in the Department of Labor responsible for developing and establishing occupational safety and health standards.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
Application of computer programs designed to assist the physician in solving a diagnostic problem.
Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
Laboratory and other services provided to patients at the bedside. These include diagnostic and laboratory testing using automated information entry.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.
The capability to perform acceptably those duties directly related to patient care.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Any deviation of results or inferences from the truth, or processes leading to such deviation. Bias can result from several sources: one-sided or systematic variations in measurement from the true value (systematic error); flaws in study design; deviation of inferences, interpretations, or analyses based on flawed data or data collection; etc. There is no sense of prejudice or subjectivity implied in the assessment of bias under these conditions.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)
Disease having a short and relatively severe course.
Substances used to allow enhanced visualization of tissues.
A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The levels of excellence which characterize the health service or health care provided based on accepted standards of quality.
The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Methodologies used for the isolation, identification, detection, and quantitation of chemical substances.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Systems composed of a computer or computers, peripheral equipment, such as disks, printers, and terminals, and telecommunications capabilities.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Incorrect diagnoses after clinical examination or technical diagnostic procedures.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Antibodies produced by a single clone of cells.
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
A management function in which standards and guidelines are developed for the development, maintenance, and handling of forms and records.
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Tumors or cancer of the LUNG.
The chemical and physical integrity of a pharmaceutical product.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Functions constructed from a statistical model and a set of observed data which give the probability of that data for various values of the unknown model parameters. Those parameter values that maximize the probability are the maximum likelihood estimates of the parameters.
Regular course of eating and drinking adopted by a person or animal.
Systematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature (From ALA Glossary of Library and Information Science, 1983). It often involves authenticating or validating information.
Freedom of equipment from actual or potential hazards.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Computer systems or networks designed to provide radiographic interpretive information.
Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.
Method of making images on a sensitized surface by exposure to light or other radiant energy.
A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The rate dynamics in chemical or physical systems.

Design of a randomized trial to evaluate the influence of mobile phone reminders on adherence to first line antiretroviral treatment in South India--the HIVIND study protocol. (1/138)

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Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches. (2/138)

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Is the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) effective for preterm infants with intrauterine growth restriction? (3/138)

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Current patient management of chronic myeloid leukemia in Latin America: a study by the Latin American Leukemia Net (LALNET). (4/138)

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Adolescent and young adult oncology training for health professionals: a position statement. (5/138)

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Candidate hepatitis C vaccine trials and people who inject drugs: challenges and opportunities. (6/138)

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Consensus document on controversial issues in the treatment of complicated skin and skin-structure infections. (7/138)

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Quality cancer care for adolescents and young adults: a position statement. (8/138)

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Almost 130,000 American children and adolescents have type 1 diabetes. Studies have demonstrated that intensive therapy and optimal glycemic control dramatically reduce the occurrence of complications in adolescents older than 13 years. At 12 months after initiation of a new intensive management program, Grey and colleagues studied the clinical and psychosocial factors associated with glycemic control and quality of life in adolescents with type 1 diabetes.. The study authors recruited patients aged 12 to 20 years who had used insulin therapy for at least one year. The patients had no health problems except for treated hypothyroidism, no history of hypoglycemic attacks within the previous six months, and were in the appropriate school grade according to their age within one year. Recent glycosylated hemoglobin (HbA1c) levels of 7.2 to 14.0 percent were required for inclusion in the study. The 35 male and 48 female volunteers were treated with intensive management. In addition, one half were ...
Extensively drug-resistant tuberculosis (XDR-TB) can be cured in HIV-negative patients through outpatient treatment, even in those who have received multiple prior courses of therapy for tuberculosis, according to Carole Mitnick of Harvard Medical School and her collaborators at several institutions in Boston and also in Lima, Peru. Outcomes among the XDR-TB patients in Peru were better than outcomes reported for similar patients from Europe, the United States, and Korea, where cure was achieved in fewer than half of them. The Peruvian patients had
Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.. View article ...
This phase II trial will investigate the efficacy and safety of PNT 2258 in combination with standard-of-care treatment regimen as second line treatment in
Clinical trial for Influenza Vaccine | Influenza , Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza
The Diabetes Control and Complications Trial (DCCT) recommended intensive management of type 1 diabetes mellitus in most children and adolescents,1 but little is known about strategies for implementation in youth. Home based care has been shown to be effective without increasing overall costs.2. This study by Dougherty et al used a randomised controlled trial design, which provides the least biased evaluation of an intervention. However, questions remain about the generalisability of the findings to other groups. The study participants represent a more affluent group than might be expected in general practice.. The findings of the study are impressive. The home based groups improved HbAlc after 2 years corresponds to a 10−25% reduction in the incidence of microvascular complications found in the DCCT,1 which makes the difference clinically significant. This difference occurred despite the fact that the interventions were quite similar. It is possible that the home based group achieved this ...
Health insurance plans intended to reduce unnecessary health care costs through a variety of mechanisms, including: economic incentives for physicians and patients to select less costly forms of care; programs for reviewing the medical necessity of specific services; increased beneficiary cost sharing; controls on inpatient admissions and lengths of stay; the establishment of cost-sharing incentives for outpatient surgery; selective contracting with health care providers; and the intensive management of high-cost health care cases. The programs may be provided in a variety of settings, such as HEALTH MAINTENANCE ORGANIZATIONS and PREFERRED PROVIDER ORGANIZATIONS ...
Health insurance plans intended to reduce unnecessary health care costs through a variety of mechanisms, including: economic incentives for physicians and patients to select less costly forms of care; programs for reviewing the medical necessity of specific services; increased beneficiary cost sharing; controls on inpatient admissions and lengths of stay; the establishment of cost-sharing incentives for outpatient surgery; selective contracting with health care providers; and the intensive management of high-cost health care cases. The programs may be provided in a variety of settings, such as HEALTH MAINTENANCE ORGANIZATIONS and PREFERRED PROVIDER ORGANIZATIONS ...
Bringing MOA on board at an early stage can prevent management and control problems on the operational side and in the (re)development phase. When it comes to modernizing shopping centres, MOA has all the relevant in-house knowledge to cover redevelopment in conjunction with customized financial services, thanks to cooperation with experts in fields such as asset development. MOA is located in Den Bosch, where the management, administration and secretarial support offices are based. The technical supervision of all MOA complexes is undertaken from the regional offices in Amsterdam, Barendrecht and Den Bosch. Some complexes require such intensive management that local teams are available 24 hours a day, 7 days a week ...
The neurological patient that develops respiratory failure usually has obvious neurological disease. Intubation is always indicated in respiratory failure associated with decreased ventilation. Once the patient has been stabilized, the lesion must be localized. This will help the clinician establish a list of differential diagnoses and the general prognosis for the patient. If the disease is treatable owner commitment and expectations need to be explored as these cases can require long-term intensive management.. ...
The Black-necked Stilt is a study in contrasts. Its shiny black wings and back oppose the white breast, and both are accentuated by long, bright red legs. Undisturbed, stilts wade through shallow wetlands and flooded fields with a careful grace. When disturbed during the breeding season, however, all semblance of grace disappears. Agitated stilts yap incessantly, dive at predators, and feign mortal injuries. After a day of field work near breeding stilts, the yapping echoes in ones head until the next morning when the sound is renewed by the continuing calls of vigilant parents.. Numbers of an endangered subspecies, the Hawaiian Stilt (H. m. knudseni, in Hawaiian, Aeo, one standing tall), were reduced by hunting pressure, habitat loss, and predation by introduced vertebrates to as few as 200 individuals in the early 1940s. With intensive management, including a ban on shooting, numbers have now (1990s) recovered to more than 1,400 individuals. Hawaiian Stilts occur in lowland coastal ...
by Steve Suther for Angus Productions Inc. JOPLIN, Mo. (Sept. 1, 2011) - The simplest and most direct way to pregnancy-test is to wait until the cow gives birth, but economics push herd managers to diagnose the condition much sooner.. Discarding one other simple solution, University of Missouri (MU) dairy scientist Matt Lucy said, After AI (artificial insemination), the cleanup bull does the best job of finding which cows didnt get bred - if only he would write down the numbers.. Lucy presented more feasible alternatives Thursday, Sept. 1, at the Applied Reproductive Strategies in Beef Cattle (ARSBC) meeting in Joplin, Mo. With todays more intensive management strategies - such as heat synchronization and fixed-time AI (FTAI), the next frontier in beef is a second synchronized AI, he said.. Although rectal palpation is the most widely used means of pregnancy diagnosis, even its soonest possible result 30-35 days after AI is too late for practicality. Ultrasound is not much better, ...
Ewa Ehrenborg is currently working in Karolinska University Hospital, Sweeden. Ewa Ehrenborg international experience includes various programs, contribution..
If gout sufferers eat numerous food containing purines (a chemical) then uric acid can type, resulting in gout. The success of any plan for dropping pounds depends on your willpower. Vegetables, fruits, meat, seafood, nuts, seeds, and wholesome fats comprise the foods included on the Paleo Eating regimen. Being regular is not just a psychological decide-me-up, it is necessary for good health and weight reduction. Some action plan is unquestionably required if one must drop extra kilos in 10 days. Eating in patterns like this is called calorie shifting. To begin with, you need to understand a very powerful thing of all. This unbiased data may help you determine if this food routine is greatest for you. The esa is straightforward proper proper here, you dr ewa dabrowska dieta enhance your train and in the discount of your meals dr ewa dabrowska dieta. Optimistic, theres. Of us on the internet have recurrently flashing adverts and dabrwoska concerning the complete merchandise that assist you to to ...
Patients with oligometastatic disease (OMD) often have controllable symptoms, and cures are possible. Technical improvements in surgery and radiotherapy have introduced the option of metastasis-directed ablative therapies as an adjunct or alternative to standard-of-care systemic therapies. Several clinical trials and registries are investigating the benefit of these therapeutic approaches across several cancer sites. This requires that patients are correctly included and followed with appropriate imaging. This article discusses the evidence and offers recommendations for the implementation of standard-of-care (Response Evaluation Criteria in Solid Tumours measurements on computed tomography [CT], magnetic resonance imaging [MRI] and bone scintigraphy) and advanced imaging modalities (functional, metabolic and radionuclide targeted) for identifying and following up patients with OMD ...
Treatment will be administered in two phases, an induction and a maintenance phase, as described below. Subjects will continue induction treatment for up to 1 year. Treatment in the study will be discontinued if the subject experiences progressive disease (PD) or unacceptable toxicity (not corrected with dose reduction), withdraws consent, or if the Investigator feels it is no longer in the subjects best interest to continue treatment. Those who have a complete response (CR) in the induction phase will enter the maintenance phase of the study. Subjects who experience ongoing stable disease (SD) or an ongoing partial response (PR) at 1 year may enter the maintenance phase at the Investigators discretion. Subjects may remain on the maintenance phase of the study for up to 1 year. Treatment will continue in the maintenance phase until the subject experiences PD or unacceptable toxicity (not corrected with dose reduction), withdraws consent, or if the Investigator feels it is no longer in the ...
For patients taking angiotensin-converting enzyme (ACE) inhibitors (ACE-I) or angiotensin-receptor blockers (ARBs), non-statin lipid-modifying therapy, thiazolidinediones, inhaled steroids, or leukotriene modifying agents, use of a stable dose for at least 6 weeks prior to screening and capable of continuing with that dose for the duration of the ...
Currently there is a tremendous amount of research interest in acute reperfusion therapy for patients suffering from acute ischemic stroke. However, other aspects of patient care in acute and subacute stroke are typically considered routine and thus have received less attention. The present guidelines emphasize medical management during the first 24-48 hours after infarction, but do little to address the management in the remainder of hospitalization.
Currently there is a tremendous amount of research interest in acute reperfusion therapy for patients suffering from acute ischemic stroke. However, other aspects of patient care in acute and subacute stroke are typically considered routine and thus have received less attention. The present guidelines emphasize medical management during the first 24-48 hours after infarction, but do little to address the management in the remainder of hospitalization.
chuyển nhà thành hưng hà nội Ước muốn trở thành gái bán hoa Ewa Malanda sinh ngày 16/7/1984 tại Koszalin, Ba Lan. Khi Ewa vẫn còn là bào thai trong bụng mẹ, bố của Ewa, vốn là một tay giang hồ máu mặt, đã bị bắt giữ với tội danh giết người. Vì vậy, 3 năm đầu đời của cô bé Ewa dành cho những cuộc trốn chạy, mẹ cô lo sợ tính mạng của bản thân và con gái sẽ gặp nguy hiểm bởi kẻ thù của bố cô đe dọa rằng sẽ không để gia đình cô yên. Khi Ewa vừa bước qua tuổi thứ 3, mẹ đã đưa cô rời khỏi Ba
chuyển nhà thành hưng hà nội Ước muốn trở thành gái bán hoa Ewa Malanda sinh ngày 16/7/1984 tại Koszalin, Ba Lan. Khi Ewa vẫn còn là bào thai trong bụng mẹ, bố của Ewa, vốn là một tay giang hồ máu mặt, đã bị bắt giữ với tội danh giết người. Vì vậy, 3 năm đầu đời của cô bé Ewa dành cho những cuộc trốn chạy, mẹ cô lo sợ tính mạng của bản thân và con gái sẽ gặp nguy hiểm bởi kẻ thù của bố cô đe dọa rằng sẽ không để gia đình cô yên. Khi Ewa vừa bước qua tuổi thứ 3, mẹ đã đưa cô rời khỏi Ba
Visit Healthgrades for information on Dr. Ewa Mrozek, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Background: -Patients who are being evaluated and / or treated at the NIH Clinical Center (pediatric and adult) and adult patients at participating sites will be entered onto this tissue procurement protocol for collection of tissue specimens. Objectives: - To obtain samples from adult and pediatric patients for research purposes from tests and procedures that are done as required by the primary research protocol(s) to which a patient is enrolled or as part of their standard-of-care treatment. - To obtain samples for research purposes from non-surgical procedures, such as percutaneous biopsies, performed for the sole purpose of obtaining tissue specimens or biological fluids for this protocol. Eligibility: -Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and / or treated for cancer at the NIH Clinical Center and adult patients from participating sites. Design: - This is a multicenter tissue procurement protocol with NCI ...
Sex addiction?: This is a pop concept, not a standard-of-care psychiatric diagnosis -- from a movement with an agenda. The goal of monogamy is laudable; the additional goal of not enjoying ones own body or own thoughts at all seems unrealistic and sure to fail. Your real question is, can this relationship be monogamous? this is far deeper than any pop diagnosis. Get good advice and perhaps sane therapy. ...Read more ...
Make sure to remember your password. If you forget it there is no manner for StudyStack to ship you a reset hyperlink. You would wish to create a brand new account.. Did you already know… We have over 95 college courses that prepare you to earn credit by examination that is accepted by over 2,000 colleges and universities. You can take a look at out of the first two years of faculty and save hundreds off your diploma. Anyone can earn credit score-by-examination regardless of age or schooling stage. Current Author Addresses: Dr. Qaseem: American College of Physicians, one hundred ninety N. Independence Mall West, Philadelphia, PA 19106.. Treatment: measurement of nocturnal blood glucose ranges; before initiating insulin remedy The long-appearing insulin dose could also be given later (round 11 p.m.) or elevated beneath careful glycemic management. Treatment with an insulin pump could also be considered in kids. I guess my query can be why they didnt just inform the cop to cease tasing the guy ...
Over the years I was managing and leading international and natural beauty brands in France, UK and the US. I knew I could develop something unique on the market and one of a kind products for pregna
US patients with multiple sclerosis could soon gain access to a new treatment option after the US Food and Drug Administration approved Biogen and AbbVies once-monthly, self-administered subcutaneous injection Zinbryta. - News - PharmaTimes
TEAM EWA EHRENBORG. The aim of the Ehrenborg team is to characterize physiological and molecular consequences of genetic variability in important proteins involved in the development of cardiovascular metabolic diseases and investigate the regulation of these proteins.. ...
Psychiatria Polska 2012, tom XLVI, numer 5 strony 757-769 Funkcjonowanie poznawcze osób z chorobą niedokrwienną serca leczonych kardiochirurgicznie - ocena przed i po zabiegu. Badania pilotażowe The cognitive functioning of patients with heart disease treated cardiosurgically - assessment before and after surgery. Preliminary study Janusz Stążka 1 , Ewa Małgorzata Sz e p i e t o w s k a 2 , Ewelina Ba r a ń s k a 2 , Piotr D u d k a 1 Klinika Kardiochirurgii UM w Lublinie
Adrian Sm dowski2, Anna Piotrowska-Gw d 2, Karolina Miku 2, Agnieszka Piotrowska2, Agnieszka Fitowska2, Marta Kaczmarek2, Dorota Pojda-Wilczek1, Ewa Mrukwa-Kominek1 ...
Kapusta-Duch, Joanna / Bieżanowska-Kopeć, Renata / Smoleń, Sylwester / Pysz, Mirosław / Kopeć, Aneta / Piątkowska, Ewa / Rakoczy, Roksana / Koronowicz, Aneta / Skoczylas, Łukasz / Leszczyńska, Teresa ...
AUTORZY: Alina Mieczkowska, Adriana Schumacher, Natalia Filipowicz, Anna Wardowska, Maciej Zieli ski, Piotr Madanecki, Ewa Nowicka, Paulina Langa, Milena Deptu a, Jacek Zieli ski, Karolina Kondej, Alicja Renkielska, Patrick G. Buckley, David K. Crossman, Michael R. Crowley, Artur Czupryn, Piotr Mucha, Pawe Sachadyn, ukasz Janus, Piotr Skowron, Sylwia Rodziewicz-Motowid o, Miros awa Cichorek, Micha Piku a, Arkadiusz Piotrowski. ...
Your Ewa Beach orthopedic medicine information resource for athletes and anyone else with any kind of joint pain. Find the local information and resources you need in Ewa Beach, HI. Whether youre looking for Ewa Beach orthopedic surgeons, doctors, hospitals, surgery, or medical consultation, this page will help you get the information you are searching for.
Nesoenas mayeri survives in the Black River Gorges of south-west Mauritius and on Ile aux Aigrettes, just off the eastern coast. Although once common, it declined to just 10 wild individuals in 1990, and were it not for intervention, it would have rapidly gone extinct. Since then, intensive management has resulted in a spectacular increase, although the population is still dependent on ongoing intensive management. Since 2000 the population has remained above 300 individuals; numbers have fluctuated but in April 2007 there were 380 birds (C. Jones in litt. 2007), in April 2010 the population was estimated at 376-493 birds (V. Tatayah in litt. 2010) and in December 2011 estimated at 365 known individuals from six subpopulations (five in the national park and one on Ile aux Aigrettes), and so a possible total population of 370-380 individuals (Jones et al. 2013), although releases have now occurred at an additional, seventh site (Tatayah 2013). In 2007, of the five established subpopulations, two ...
BUFFALO, N.Y. - A new study led by vision researchers at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo and VA Western New York Healthcare System has demonstrated that the addition of widely available antioxidants to the current standard-of-care prevented vision loss in an animal model of a rare genetic disease.. Published in the Jan. 19 issue of Scientific Reports, the paper describes the combination therapy that resulted in preventing the retinal degeneration that can occur in babies born with Smith-Lemli-Opitz Syndrome (SLOS).. Caused by the bodys inability to make cholesterol, the disease is a birth defect that results in multiple neurosensory and cognitive abnormalities, physical deformities and disabilities, including vision loss. In severe cases, it can be fatal.. Using our combination therapy approach, we were able to prevent otherwise progressive and irreversible retinal degeneration from occurring in a rodent model of this hereditary human ...
HERES WHY IT SHOULD NOT BE SHUT DOWN:. Ewa Village Post Office is at the center of one of the fastest growing communities in West Oahu according to the last census. Even Ewa Village has been adding more homes recently and many more are planned nearby. This is by no means a dying community even though a large elderly population lives in the village and is very grateful that this type of very friendly island village post office still exists.. The closure letter states that the building is not listed as an historic landmark- but in fact it is now over 50 years old and National Register eligible. The historic plantation era building was built in 1958 and was given to the City when the plantation closed. This is one of the least expensive Oahu post offices to run as far as space rent is concerned.. The postal letter informing about the possible Ewa Village P.O. admits that the historic cinder block building has no known structural defects, safety hazards or security issues.. Just last year ...
The European Society of Cardiology together with the European Atherosclerosis Society published updated dyslipidaemia guidelines in 2011. SA Heart and the Lipid and Atherosclerosis Society of Southern Africa officially adopt these guidelines. This statement adapts aspects of the guidelines to the South African situation. Using the updated Framingham risk charts, interventional strategies are based according to the cardiovascular risk score and low-density lipoprotein cholesterol (LDL-C) levels. The Framingham risk score refers to the 10-year risk of any cardiovascular event, and includes four categories of risk. Treatment targets are those of the European guidelines. The LDL-C goal is 1.8 mmol/l for the very high-risk group (>30%), 2.5 mmol/l for the high-risk group (15 - 30%), and 3 mmol/l for those below 15% risk. Intensive management of dyslipidaemia in South Africa will significantly reduce the cardiovascular disease health burden.
Mental health disorders affect millions of US adults each year, of all ages, genders and socioeconomic groups. Some disorders are mild, while others are more disabling and require intensive management and care. The majority of people suffering from mental disorders can effectively return to normal, productive lives if they receive appropriate treatment, and this treatment is readily available. At UTMB Health, our mental health professionals are dedicated to helping you and your family on the path to mental health and wellness, with compassionate expertise and evidence-based therapies and treatments. We look forward to helping you ...
Nearly a third of the parks flora is non-native, and some of these species are extremely invasive and threaten the integrity of natural communities. Purple loosestrife is one species that has been actively managed at the park since 1988 using an integrated pest management (IPM) strategy. Staff monitor wetlands annually for the presence of this species and treat observed individuals with a glyphosate herbicide application. Based on 15 years of intensive management, purple loosestrife populations at Acadia National Park are at very low levels.. Park staff are working to restore natural areas in the park that have been degraded by visitor impacts or construction activities. Sites are first stabilized, then planted with native plants. Acadia National Park maintains a nursery of plant materials propagated from native park vegetation. Staff monitor restored sites annually to assess additional maintenance needs, identify continued visitor impacts, and evaluate the overall success of the work.. The ...
Wolves and bears could be in serious trouble if some of the BOG proposals are passed. Proposal 103 seeks to reauthorize the Intensive Management Plan for wolf and black bear control in Unit 16 for an additional 6 years. The Alaska Department of Fish and Game recently amended the proposal to include a brown bear predation control experiment which could allow for more of these animals to be killed. ...
Ewa Sonnet Height Weight Age Bra Size Affairs Body Stats.Ewa Sonnet body measurements statistics figure breast size affairs with boy friends list.
This is a Phase 2 multicenter, randomized, double-blind, placebo-controlled, add-on study of NBP softgel capsules for the treatment of mild to moderate cortical
Title: A Workflows Roadmap for the Geosciences  Author: Gil, Yolanda; Deelman, Ewa; Demir, Ibrahim; Duffy, Christopher; Marru, Suresh; Altintas, Ilkay; Pierce, Marlon E.; Wiener, Gerry; Altintas, Ilkay; Braeckel, Aaron; Browdy, Steven F.; Fulker, David; Li, Nicong; Ramirez, Paul; Tarboton, David; Weerawarana, Shahani Date: 9/15/2012 ...
EWA SCHILLING GUPIEC PDF - Listen to Eva Schilling now. Listen to Eva Schilling in full in the Spotify app. Play on Spotify. Legal · Privacy · Cookies · About Ads. To play this
Its important to take any prescribed medication regularly, as this can help keep your symptoms under control and prevent severe asthma attacks.. Its also important to use any inhalers and spacers you may have been prescribed properly. Make sure your GP or practice nurse shows you how to use your inhalers correctly.. Check with your doctor or asthma nurse if you plan to take any over-the-counter remedies, such as painkillers or nutritional supplements. These can sometimes interfere with your medication.. Some common medicines, such as aspirin and ibuprofen, may not be suitable if you have asthma. Always check the label or packet and ask a pharmacist, doctor or nurse if youre not sure.. Speak to your doctor or asthma nurse if you have any concerns about the medication youre taking, or if youre experiencing any side effects.. ...
Its important to take any prescribed medication regularly, as this can help keep your symptoms under control and prevent severe asthma attacks.. Its also important to use any inhalers and spacers you may have been prescribed properly. Make sure your GP or practice nurse shows you how to use your inhalers correctly.. Check with your doctor or asthma nurse if you plan to take any over-the-counter remedies, such as painkillers or nutritional supplements. These can sometimes interfere with your medication.. Some common medicines, such as aspirin and ibuprofen, may not be suitable if you have asthma. Always check the label or packet and ask a pharmacist, doctor or nurse if youre not sure.. Speak to your doctor or asthma nurse if you have any concerns about the medication youre taking, or if youre experiencing any side effects.. ...
This is a randomized, multi-center, open label pilot study. The primary goal of this study is to determine the safety of TA-CIN vaccine as adjuvant therapy, and to assess evidence of induction of HPV antigen-specific immunologic response when administered at different locations (arm or thigh). In this pilot study, a single dose level (100µg) assessment of the safety and tolerability of administering TA-CIN vaccine three times to either the arm versus the thigh of patients who have previously been treated for HPV16-related cervical cancer in the past year and are documented to have no evidence of disease recurrence based on standard-of-care imaging and/or clinical assessment upon eligibility. A total of 14 patients will be enrolled to assess the safety of TA-CIN vaccine via different injection sites as adjuvant therapy. Safety assessments will continue for a period for 1 month after the last vaccination. Few or no serious adverse events (SAEs) are expected from this regimen and routes of ...
History: Diffusion of new cancers treatments could be both inefficient and incomplete. Outcomes: We discovered 6561 metastatic prostate cancers sufferers; 1350 received chemotherapy subsequently. Among sufferers who received chemotherapy docetaxel make use of was 95% by 2008. Docetaxel uptake was statistically considerably slower (< .01) for sufferers over the age of 65 years blacks sufferers in low income areas and the ones who experienced poverty. Eighty percent of docetaxel diffusion happened before the Might 2004 discharge of stage III results displaying superiority of docetaxel over standard-of-care. The utmost increase in the speed useful of docetaxel happened nearly concurrently for prostate cancers as for all the cancers mixed (in 2000). Bottom line: Efforts to improve RCAN1 the diffusion of remedies with proven success benefits among disadvantaged populations may lead to cancers population survival increases. Docetaxel diffusion mainly preceded stage III evidence because of its ...
Though cancer immunotherapy has become a promising standard-of-care treatment-and in some cases, perhaps a cure-for a wide variety of different cancers, it doesnt work for everyone, and researchers have increasingly turned their attention to understanding why.
The mainstream, standard-of-care treatment for brain tumors consists of some combination of resection (surgery to remove the tumor), radiation (destroying cancer cells with a precision-shaped beam of energy), and chemotherapy (the use of powerful drugs that are toxic to tumor cells. These are all effective to some degree, and though none of them represent a cure, all are important tools to be used by oncologists. There is much ongoing research to improve techniques in all three areas.. At the same time, many researchers and firms are seeking on approaches to complement these three core techniques. Many of these have promising science behind them, and appear to be gaining a place in the toolkit as well.. A word of caution: these approaches are at various places in the clinical trial / approval pipeline, and patients should discuss with their doctors, or a team at a major brain tumor center, to identify a treatment strategy for you.. ...
The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?
The Lancet Infectious Diseases Median consumption of antibiotics was 7.5 daily defined doses (DDD) in the procalcitonin-guided group v 9.3 DDD in the standard-of-care group (absolute difference 2.69, p|0.0001), and median duration of treatment was 5 v 7 days respectively (absolute difference 1.22, p|0.0001).
Biopsy of soft-tissue and bone lesions is a difficult procedure that is fraught with complications if obtained improperly. Occasionally, improperly performed biopsies may preclude limb-salvage, thus greatly altering the outcome of the disease process. Because of this, it is considered standard-of-care to refer patients with possible musculoskeletal tumors to treatment centers capable of proper diagnosis and management of the condition. While a community orthopaedic surgeon may know how to properly biopsy a lesion, it is in the patients best interest to be referred to a treatment center prior to biopsy if that surgeon does not feel comfortable managing the patient afterwards ...
LynxBios cytomics-based platform technology, MicroC3™, rapidly measures the therapeutic response of patients own blood cancer cells to drugs. MicroC3™ seamlessly integrates into the clinical workflow and provides physicians with actionable results within 72 hours of a standard-of-care biopsy.. ...
Recommendations in the report highlight the importance of patient-centered decision making for glycemic management and improving diet and exercise for patients with T2D.
Hypoglycemia in Diabetes focuses on the prevention and treatment of hypoglycemia with careful attention to glycemic management of diabetes.
Hypoglycemia in Diabetes focuses on the prevention and treatment of hypoglycemia with careful attention to glycemic management of diabetes.
HOUSTON — Standardized continuous glucose monitoring metrics and time-in-range targets can help patients and diabetes care and education specialists work together to achieve agreed-upon goals and personalize glucose management decisions, according to two speakers at the American Association of Diabetes Educators annual meeting. “CGM has the potential to transform glycemic management
Therapeutic results of various doses of prebiotic (remoted from S accharomyces cerevisiae) compared to n-Three complement on glycemic management, lipid profiles and immunological response in diabetic rats Background: The common consumption of fiber generates… Read more ». ...
The LMCB is a hub for molecular cell biology in the UK and beyond. Our mission is to develop new molecular understandings of cell function through discovery-based research and technology development.
Małgorzata Manowska, Katarzyna Kornacka, Elżbieta Gajewska, Janusz Gadzinowski, Małgorzata Dzwonkowska, Iwona Domżalska, Agnieszka Domańska, Iwona Dąbrowska-Wójciak, Michał Bociański, Ewa Musialik-Świetlińska, Klaudiusz Bober, Janusz Świetliński, Jerzy Szczapa, Marta Orczyk, Andrzej Piotrowski, Magdalena Rutkowska, Dorota Rytko, Ewa Terpińska, Adam Thrun. Med Sci Monit 2004; 10(2): 7-13 :: ID: 11858. Published: 2004-05-20, Viewed (4441), Downloaded (847), Related (0), Cited (0) ...
Baranowska B, Wolinska-Witort E, Wasilewska-Dziubinska E, Roguski K, Martynska L, Chmielowska M. The role of neuropeptides in the disturbed control of appetite and hormone secretion in eating disorders. Neuro Endocrinol Lett. 2003 Dec; 24(6): 431-434 ...
Weather this weekend was not very helpful for birdwatching. Yesterday very strong wind, today nice in the morning - the above picture was taken abt 10.oo am. In the afternoon winter came - see picture below. I was thinking, that I will not be able to report any birds around - what a strange feeling that would be. But no! I proudly report that I traced some of the feather fellows around. Unfortunately it is very poor result ...
Wiktorska J, Lewinski A, Stuss M, Nowak D, Pietras T, Sewerynek E. Effects of certain antioxidants on lipid peroxidation process in lung homogenates of L thyroxine-receiving rats. Neuro Endocrinol Lett. 2010 Jan; 31(1): 137-146 ...
Description Were sorry, but this activity is over. The last meeting was Saturday, November 5, 2016. Honu (5 Years & Older) Pre-requisite: Tangs. Free-style,...
Chwatko, Grażyna / Forma, Ewa / Wilkosz, Jacek / Głowacki, Rafał / Jóźwiak, Paweł / Różański, Waldemar / Bryś, Magdalena / Krześlak, Anna ...
Tytu : Argumentacja w edukacji: postulaty bada edukacyjnych w Polskiej Szkole Argumentacji / Micha Federowicz, Marcin Koszowy, Anna Bendrat, Kinga Bia ek, Krzysztof Biedrzycki, Katarzyna Budzy ska, Agnieszka Budzy ska-Daca, Dawid Czaczkowski, Piotr Francuz, Martin Hinton, Marcin Karpi ski, Filip Kobiela, Robert Kublikowski, Szymon Maku a, Marcin Selinger, Bart omiej Skowron, Andrzej Stefa czyk, Wojciech Sucho , Agnieszka Su owska, Magdalena Swat-Pawlicka, Barbara ciga a-Stiller, Ewa Wasilewska-Kami ska, Krzysztof A. Wieczorek, Olena Yaskorska, Maria Za ska, Ma gorzata Zambrowska, Tomasz urek, Natalia yluk ...
Wón wužórli so južnje turkowskeho města Erzurum w Bingölskich horinach a ćeče potom přewažnje do wuchodneho směra, najprjedy přez wuchodnu Anatolisku a nimo hory Ararat. Tule tworja hranicu mjez Armenskej na sewjernym (lěwym) brjoze a Turkowskej na južnym (prawym). Pozdźišo je Aras pomjezna rěka mjez Iranom na prawym boku a azerbajdźanskej eksklawu Nachičewan na lěwym kaž tež mjez Armenskej a Iranom. W Azerbajdźanje samym běži najprjedy přez Mugansku stepu a wuliwa so naposledk blisko městačka Sabirabad wotprawa do Kury. ...
Two HIV drugs in development show promise for less-frequent dosing, recent research has found. One of the drugs, a fusion inhibitor (remember those?), ...
SwissPOD Standard Reporting: Vergleich Transplantationszentren - 1. Halbjahr 2014 Population: Population: Alle Todesfälle in Erwachsenen-Intensivstationen in Transplantationszentren. ...
"Meet the Board". CARE India. Retrieved 28 July 2014. "Nachiket Mor: The return of the prodigy". The Economic Times. 9 October ... "Lunch With BS: Nachiket Mor". Business Standard. 16 December 2008. Retrieved 28 July 2014. "Ex-banker Nachiket Mor set to ... He is also the Chairman of the board of directors of CARE India. Mor was born into a farming family in Yavatmal, Maharashtra. ... Manojit Saha (4 November 2013). "RBI may have more role for Nachiket". Business Standard. Retrieved 28 July 2014. "Why the ...
... in or leaving care, or receiving social care services. The Children's Commissioner states that they "will use our powers and ... "Standard-Setting Instruments". Portal.unesco.org. Retrieved 2015-10-22. "Victoria Climbie Inquiry Report". Victoria-climbie- ... Other areas may include day care, education and health. The act compromises 6 parts and detailed the role of the Children's ... The Children Act 1989 covers some key issues such as parent and child relationships; public child care law dealing with ...
Scovell, S (2010). "Role of the nurse-to-nurse handover in patient care". Nursing Standard. 24 (20): 35-39. doi:10.7748/ ... Change-of-shift report is key to inpatient care because healthcare providers (nurses, physicians, nursing assistants etc.) are ... Wywialowski, Elizabeth F (2004). Managing Client Care. Elsevier Health Sciences. pp. 167-182. ISBN 9780323024822. ... essential to providing around the clock care. During report, the outgoing nurses discuss with the oncoming nurses the condition ...
"Radical Self-Care". Slate. "So-Ko your skin: why South Korean skincare is serious stuff (despite its cutesy packaging)". ... Evening Standard. "I Do K-Beauty (And You Can, Too)". Clinique. "Watch out K-beauty, we're going global: East-meets-west ... Cosmetics in Korea "K-Beauty: The Exhausting Skin-Care Regimen That May Be Worth the Effort". The Wall Street Journal. "This ... K-Beauty is an umbrella term for skin-care products that derive from South Korea. The fad gained popularity worldwide, ...
Evening Standard. 16 July 2014. Retrieved 22 March 2015. "Chelsea and Westminster Hospital NHS Foundation Trust". Care Quality ... In the neonatal intensive care unit there was a 26% vacancy rate and staff claimed that a culture of bullying existed. One of ... "West Middlesex University Hospital NHS Trust". Care Quality Commission. Retrieved 9 September 2015. "Chelsea and Westminster ... which had developed national standards. It was named by the Health Service Journal as one of the top hundred NHS trusts to work ...
London Evening Standard. p. 25. "Care Act 2014". www.legislation.gov.uk. Retrieved 2016-05-31. "The Care Act: Safeguarding ... The Care Act 2014 introduced new legislation regarding safeguarding vulnerable adults. The Act sets out a legal framework for ... "Safeguarding people". Care Quality Commission. 18 June 2014. Retrieved 9 December 2014. "What is safeguarding and why does it ... Adults in need of safeguarding help are generally elderly and frail, and either live alone or in care homes with little support ...
Diabetes Care. 27 (1): 155-61. doi:10.2337/diacare.27.1.155. PMID 14693982. "Orlistat Side Effects". "POISONS STANDARD JUNE ... at the standard over-the-counter dose of 60 mg. Higher doses do not produce more potent effects. Orlistat has historically been ... At the standard prescription dose of 120 mg three times daily before meals, orlistat prevents approximately 30% of dietary fat ...