The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.
The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)
The privacy of information and its protection against unauthorized disclosure.
Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
Rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythematous, papular, vesicular, or bullous lesions. The disease is strongly associated with the presence of HLA-B8 and HLA-DR3 antigens. A variety of different autoantibodies has been detected in small numbers in patients with dermatitis herpetiformis.
The science and application of a double-beam transmission interference microscope in which the illuminating light beam is split into two paths. One beam passes through the specimen while the other beam reflects off a reference mirror before joining and interfering with the other. The observed optical path difference between the two beams can be measured and used to discriminate minute differences in thickness and refraction of non-stained transparent specimens, such as living cells in culture.
A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.
Pathologic inclusions occurring in erythrocytes.
Surgical procedure involving either partial or entire removal of the spleen.
A diet which is devoid of GLUTENS from WHEAT; BARLEY; RYE; and other wheat-related varieties. The diet is designed to reduce exposure to those proteins in gluten that trigger INFLAMMATION of the small intestinal mucosa in patients with CELIAC DISEASE.
Prolamins in the endosperm of SEEDS from the Triticeae tribe which includes species of WHEAT; BARLEY; and RYE.
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
A subspecialty of pathology applied to the solution of clinical problems, especially the use of laboratory methods in clinical diagnosis. (Dorland, 28th ed.)
A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
Tests used in the analysis of the hemic system.
Societies whose membership is limited to pharmacists.
Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.
A genus of gram-negative, mostly facultatively anaerobic bacteria in the family MYCOPLASMATACEAE. The cells are bounded by a PLASMA MEMBRANE and lack a true CELL WALL. Its organisms are pathogens found on the MUCOUS MEMBRANES of humans, ANIMALS, and BIRDS.
Infections with species of the genus MYCOPLASMA.
Invertebrates or non-human vertebrates which transmit infective organisms from one host to another.
A genus of gram-negative bacteria characteristically appearing in chains of several segmenting organisms. It occurs in man and arthropod vectors and is found only in the Andes region of South America. This genus is the etiologic agent of human bartonellosis. The genus Rochalimaea, once considered a separate genus, has recently been combined with the genus Bartonella as a result of high levels of relatedness in 16S rRNA sequence data and DNA hybridization data.
A genus of tick-borne protozoan parasites that infests the red blood cells of mammals, including humans. There are many recognized species, and the distribution is world-wide.
Tumors or cancer of the SPLEEN.
A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.
A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
A general term for various neoplastic diseases of the lymphoid tissue.
Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
A dull red, firm, dome-shaped hemangioma, sharply demarcated from surrounding skin, usually located on the head and neck, which grows rapidly and generally undergoes regression and involution without scarring. It is caused by proliferation of immature capillary vessels in active stroma, and is usually present at birth or occurs within the first two or three months of life. (Dorland, 27th ed)
A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus in the postembryonic period, after the major structures have been outlined. In humans, this corresponds to the period from the third month after fertilization until birth.
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow, and the potential for reversal by splenectomy.
The condition of being heterozygous for hemoglobin S.
An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.
Professional society representing the field of medicine.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
A publication issued at stated, more or less regular, intervals.
An encapsulated lymphatic organ through which venous blood filters.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
A computer architecture, implementable in either hardware or software, modeled after biological neural networks. Like the biological system in which the processing capability is a result of the interconnection strengths between arrays of nonlinear processing nodes, computerized neural networks, often called perceptrons or multilayer connectionist models, consist of neuron-like units. A homogeneous group of units makes up a layer. These networks are good at pattern recognition. They are adaptive, performing tasks by example, and thus are better for decision-making than are linear learning machines or cluster analysis. They do not require explicit programming.

Colchicine inhibition of the first phase of amyloid synthesis in experimental animals. (1/409)

Colchicine was found to inhibit the first phase of casein-induced synthesis of murine amyloid. When mice were treated with colchicine during the first 7 days of an amyloid induction regimen or when colchicine was given to the donor mice in a transfer model, the amyloidogenic stimulus of casein was blocked completely. Amyloid synthesis was however, not interrupted by the administration of colchicine during the last 7 days of the casein regimen nor by colchicine treatment of recipient mice in a transfer model.  (+info)

Effectiveness of a vaccine against red sea bream iridoviral disease in a field trial test. (2/409)

Since 1990, red sea bream iridovirus (RSIV) has caused high mortalities in the summertime in cultured red sea bream Pagrus major in southwest Japan. To establish control measures for red sea bream iridoviral disease (RSIVD), the effectiveness of a formalin-killed viral vaccine was evaluated in a field trial. Two groups each consisting of 1000 juvenile red sea bream were either intraperitoneally inoculated with vaccine (vaccinated group) or were not vaccinated (non-vaccinated group). After vaccination, the fish were held for 1 wk, then transferred to a marine net pen and observed for 12 wk. The cumulative mortalities caused by RSIVD in the vaccinated group or control group were 19.2 and 68.5%, respectively. Additionally, the presence of virus antigen in the spleen was investigated and body weight was measured 6 and 12 wk post vaccination. In the vaccinated group, viral antigen was not detected. The increase in body weight of vaccinated fish was significantly (p < 0.05) greater than that of control fish. These results suggest that the vaccine against RSIVD was effective in 1 field trial.  (+info)

The real incidence of extracapsular (satellite) cysts of liver echinococcus. (3/409)

BACKGROUND: The presence of extracapsular (Satellite) cysts in liver echinococcus granulosus is known for many years. In one of our previous studies of radiological (CT) material they were found to be present in 16% of cases. METHODS: In the present study the operative findings, in cases of total capsectomy (cystopericystectomy) or partial lobectomy are presented. RESULTS: The real incidence of these cysts in operative specimens was as high as 29,5%. They were present in 15 out of 51 totally excised cysts. CONCLUSIONS: We conclude that satellite cysts are present more often than they are radiologically detected. As they can be incriminated as a cause of recurrence of the disease they must be excised en block with the main parasitic cysts, by means of more radical procedures such as cystopericystectomy or partial hepatectomy, whenever it is feasible.  (+info)

Relationship between circulating antigen level and morbidity in Schistosoma mansoni-infected children evaluated by ultrasonography. (4/409)

Ninety-eight Schistosoma mansoni-infected children from an endemic area in Sharkia Governorate, Egypt were evaluated by abdominal ultrasonography to determine liver and spleen sizes, grade of periportal fibrosis, and splenic vein diameter. Circulating antigen levels were measured using a double sandwich ELISA in which the sensitivity was 91.8% and specificity was > 99%, with no evidence of cross-reactivity with other parasites. No significant relationship was observed between antigen level and clinical stages of the disease as assessed by physical examination (P > 0.05). When ultrasound was used to stage disease, the mean antigen level was significantly higher among hepatosplenic cases than intestinal cases (P < 0.05). No difference in mean antigen levels were found between the splenic and hepatic cases. Furthermore, a direct correlation (P < 0.01) was observed between antigen level and disease severity as monitored by ultrasonography. Antigen level showed a positive correlation with the degree of periportal fibrosis (P < 0.05). Moreover, a significant increase in the percent of children who were antigen positive (> 80 ng/ml) was found in those with more severe periportal fibrosis (P < 0.001). The findings suggest that ultrasonography along with measurement of circulating antigen levels predict morbidity in schistosomiasis mansoni.  (+info)

Splenic myeloid metaplasia, histiocytosis, and hypersplenism in the dog (65 cases). (5/409)

Splenectomy specimens from 65 dogs with severe, diffuse, sustained, and progressive splenomegaly were examined. The clinical signs, hematology, and serum chemistry values in for the dogs were not useful diagnostic features. Microscopic changes in the spleens were distinctive and consisted of 1) myeloid metaplasia, 2) histiocytosis, 3) erythrophagocytosis, and 4) thrombosis with segmental infarction. Ultrastructural features suggested proliferative changes in the splenic reticular cells and macrophages (reticular meshwork) that described a continuum from reactive changes associated with immunologic damage of erythrocytes to neoplastic proliferation of histiocytic components. Thirty percent of the dogs survived 12 months. Approximately one half (53%) of the dogs with complete postmortem evaluations showed multiorgan involvement with a tissue distribution and cell morphology consistent with histiocytic neoplasia. For the remaining dogs (47%), only splenic pathology was consistently present, and a specific cause of death was often not evident. Distinctive histologic changes in the splenic tissues-including mitotic activity, erythrophagocytosis, giant cell formation, thrombosis/ infarction, and the proportion and distribution of histiocytic and hematopoietic cells-were statistically evaluated for prognostic relevance. The presence of giant cells was the only reliable prognostic feature, and that was indicative of a fatal outcome. These descriptive changes of myeloid metaplasia in the canine spleen are compared with the human clinical and pathologic syndromes of 1) agnogenic myeloid metaplasia, 2) hemophagocytic syndromes, and 3) hypersplenism. These diseases in humans produce histopathologic changes in the spleen that are similar to those observed in the canine splenic tissue we examined in this study.  (+info)

Pathology of the spleen in hepatosplenic schistosomiasis. Morphometric evaluation and extracellular matrix changes. (6/409)

Histological, ultrastructural, morphometric and immunohistochemical data obtained from the study of spleens removed by splenectomy from 34 patients with advanced hepatosplenic schistosomiasis revealed that the main alterations were congestive dilatation of the venous sinuses and diffuse thickening of the splenic cords. Splenic cord thickening was due to an increase of its matrix components, especially type IV collagen and laminin, with the conspicuous absence of interstitial collagens, either of type I or type III. Deposition of interstitial collagens (types I and III) occurred in scattered, small focal areas of the red pulp, but in the outside of the walls of the venous sinuses, in lymph follicles, marginal zone, in the vicinity of fibrous trabeculae and in sidero-sclerotic nodules. However, fibrosis was not a prominent change in schistosomal splenomegaly and thus the designation "fibro-congestive splenomegaly" seems inadequate. Lymph follicles exhibited variable degrees of atrophy, hyperplasia and fibrous replacement, sometimes all of them seen in different follicles of the same spleen and even in the same examined section. Changes in white pulp did not seem to greatly contribute to increasing spleen size and weight, when compared to the much more significant red pulp enlargement.  (+info)

Traumatic pseudocyst of the spleen. (7/409)

Four patients with pseudocyst of the spleen gave histories of abdominal trauma. In one patient the pseudocyst had ruptured, necessitating emergency splenectomy 34 years after the original injury. In a second patient the pseudocyst was discovered incidentally, and was managed by spleen-preserving excision; and the third and fourth presented with abdominal pain and had splenectomy and spleen-preserving surgery, respectively. All patients with conservatively treated splenic injury are at risk of developing a pseudocyst of the spleen, and the lesion can be detected by computed tomography or ultrasound. When there are no symptoms the natural history is unknown; but if surgery is necessary, splenectomy can sometimes be avoided.  (+info)

Videolaparoscopic approach of the splenic cyst: a case report. (8/409)

The authors report a case of an asymptomatic 30-year-old female patient with an extensive cystic lesion continuous with the splenic parenchyma. A review of the literature and use of a videolaparoscopic approach to the treatment of these lesions is presented.  (+info)

[Hepatosplenic candidiasis in acute non-lymphocytic leukemia].: Eleven patients with acute non-lymphocytic leukemia developed hepatosplenic candidiasis followin
Incidence and Causes of Splenic Abscesses. Splenic abscesses are generally rare entities (incidence 0.14 % - 0.7%) [8], but must be taken into account in differential diagnosis considerations in the event of left-side abdominal pain.. Splenic abscesses usually develop via the haematogenous route from endocarditis or immunosuppression, alternatively after splenic infarctions or (blunt) abdominal traumas in the context of superinfections of parenchymal necrosis or haematomas [16]. The most important pathogens of splenic abscesses are Escherichia coli, staphylococci, streptococci, gram-negative anaerobes, or Candida species [10]. Splenic injuries do not have to be symptomatic and can, for example, be suffered without being unnoticed in combat situations (a fall, taking of cover, a collision with a vehicle) [24]. The possibility of an abscess developing from a haematoma caused by such trauma should be included in differential diagnosis considerations if appropriate symptoms are found. Diagnostic ...
Splenic abscess is a rare disease with only few reports in small-animal practice as well as in human medicine. It has been mostly reported in immunocompromised patients or following penetrating foreign bodies. This report aims to add to the current veterinary literature on recommended diagnostic tools for splenic abscess, as well as to provide follow-up findings after successful surgical treatment. An 8-year-old male German shepherd dog was admitted to the clinic for evaluation of fever, anorexia, and lethargy for the previous 3 days. During the physical examination, a mass was palpated in the left cranioventral abdomen. Diagnostic imaging including radiography and ultrasonography revealed the presence of a large mass in the spleen and signs of peritonitis. Laboratory tests reflected highly septic pyogranulomatous inflammation and, together with imaging findings, raised a high suspicion of splenic abscess and septic peritonitis. Therapy included complete splenectomy and placement of peritoneal drainage.
New life-saving treatments for Hematological malignancies | neutropenia | chronic disseminated candidiasis | hematopoietic stem cell transplantation | invasive fungal disease in clinical trial on Hepatosplenic CANdidiasis : PETscan and Immune Response Analysis
How would I code CT guided splenic abscess drainage? A drain was placed into the splenic abscess and sewn in place. I know to use 75989 for guidance,
Capital License:A Capital License is typically purchased from the customers capital budget. It gives a customer the right to use a scenario product for an unlimited period of time and for an unlimited number of times. If an update is made to the product, customers with a Capital License will receive the update if it falls within one year from the purchase date. After that timeframe, the customer will keep the existing version of the product without future updates. In addition, Customer Service will support a Capital License for a period of one year from the purchase date.. Annual License: An Annual License is typically purchased from the customers operating budget. It gives a customer the right to use a scenario product for a Period of one year from the purchase date, for an unlimited number of times. If an update is made to the product, customers with a valid Annual License will receive the update. Customer Service will support an Annual License as long as it is active.At the end of the ...
Management of these splenic cyst is threefold: What is the nature of the cyst? Should we operate and what surgery do? Cysts are classified as congenital cyst, pseudocyst, parasitic and tumor cysts. Our case was nonparasitic splenic cysts in the absence of infectious syndrome and non-tumoral on imaging. Martin Fowler [1], have made a classification distinguishing between congenital cysts (CC) that have an epithelial lining and post traumatic pseudo cysts (PC) which do not. Therefore, the distinction between CC and pseudo cyst may be made at histology. Without the recent notion obvious trauma, there is no clinical or radiological feature which distinguish them. They appear both in the CT scan thin-walled, hypodense, and without enhancement after contrast injection [2]. This distinction based on the presence or absence of epithelial lining is challenged by Morgenstern [3], which considers that several CC are wrongly considered as PC. Indeed, the wall is discontinuous and only a careful histological ...
Vague airspace opacity within the left lung base, which partially silhouettes the left heart border near the apex, representing lingular pneumonia. Additionally, there is an ovoid soft-tissue density with peripheral calcifications seen occupying the left upper quadrant that measures 15.8cm X 12.4cm X 12.9cm, likely representing a calcified splenic cyst.
Thrombocytopenia Due to Splenic Sequestration - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
Images Genevieve Carbonatto, text Genevieve Carbonatto. An 80 year old lady presents to the Emergency Department with a 4 month history of feeling unwell on and off associated with a 4 kg weight loss during that time. She presented acutely because the night before she developed mild abdominal pain and vomiting. She has been investigated by her GP. Her GP had noted a left upper quadrant mass 6 weeks prior to presenting to the ED. This was thought to be related to the spleen. An urgent ultrasound as an outpatient was reported as normal - no abdominal pathology was identified.. On arrival she is well and triaged category 4. She is no longer nauseous and has no abdominal pain. She has, on examination, a left upper quadrant mass which clinically appears to be her spleen ? splenomegaly. Her bloods were unremarkable.. A focussed point of care ultrasound was performed.. The following is a longitudinal view on ultrasound over the palpable, non tender left upper quadrant mass. The mass is bowel. There is ...
In the study presented here, PCR detected a higher prevalence of VBP in dogs with splenic alterations (16.67%) as compared with dogs without evidence of splenic changes (3.3%), which supports a potential relationship between the pathogenesis of CVBD and splenic diseases.. To the best of our knowledge, the literature contains only one report by Varanat and collaborators on molecular prevalence of certain VBP in dogs with specific splenic conditions [4]. In the latter study, Bartonella spp. DNA was more frequently detected in FHN (29.7%), HSA (26%) and LNH (10%) compared to Babesia spp. (2.7, 2.0 and 2.0%, respectively) and hemotropic Mycoplasma spp. (0, 6 and 0%, respectively), while all of the paraffin-embedded splenic tissues from dogs with histologically unremarkable spleens were PCR negative [4]. Differences observed between dogs with splenic disease and control dogs in the study of Vranat et al. [4] are in agreement with results obtained here. In contrast, specific prevalence of infection ...
The article presents a quiz related to the diagnosis and management of quadrant pain in body. It describes that case of a 21 year old female complaining left upper quadrant and loin pain with radiation to the shoulder tip, nausea, and vomiting. She had severe tenderness and guarding in the left upper quadrant and loin, in addition to left sided basal crepitations. Chest x ray revealed left basal consolidation. Abdominal ultrasound scan showed a left sided subdiaphragmatic collection associated with other abnormalities which were investigated further by subsequent computed tomography scan ...
This page includes the following topics and synonyms: Asplenic, Asplenia, Functional Asplenia, Asplenism, Hyposplenism, Hyposplenic, Postsplenectomy.
The good news is that splenic cysts are almost always benign, and mine shows no characteristics of malignancy. The bad news is that the cyst is at the very top of my spleen. The spleen, Ive learned, is sort of shaped like a pickle, or a bratwurst, and hangs out in the left side of your abdomen wedged between your diaphragm, stomach, left kidney, and the upper intestine. The top of the spleen is - I think, but I could for sure be wrong here - is above the stomach and just below the left rib cage. So anyway, the bad news is that because my cyst is up at the top of my spleen, it is much more difficult to get to. The gastroenterolgy specialist I saw last week seemed fairly certain that I would have to have a complete splenectomy. This is not good news. While you can live without a spleen, it puts you at increased risk for immune system deficiencies and getting sick more often. Apparently, if my spleen is removed, Ill have to spend at least six months on some hardcore antibiotics, and get immunized ...
Your spleen is a small organ located on the left side of your abdomen under the rib cage. It removes old red blood cells and holds on to a reserve of other red blood cells to release in an emergency, plus it helps recycle iron. Although splenomegaly (enlarged spleen) is thought of as a common cause of spleen pain, it rarely causes pain but rather discomfort and mild tenderness. The spleen is a … The spleen has an elastic capsule and is capable of expanding several times its normal size without rupturing. Under normal circumstances, when the spleen is not enlarged, it cannot be palpated. Some people are born without a spleen or need to have it removed because of disease or injury. The focal masses can be delineated by ultrasonography, computed tomography, radionuclide studies, and magnetic resonance imaging.1-4 Reports of a large series regarding focal splenic lesions by cross sectional imaging and ultrasonography are rare.1-3 5-8 Splenomegaly usually does not cause spleen pain. A splenectomy ...
ejgm71760, journal = {European Journal of General Medicine}, issn = {1304-3889}, address = {Sağlık Bilimleri Araştırmaları Derneği}, year = {2015}, volume = {9}, pages = {33 - 35}, doi = {}, title = {LAPAROSCOPİC SPLENECTOMY FOR SPLENIC CYST HYDATIC; CASE REPORT}, language = {en}, key = {cite}, author = {SÖZEN, SELİM and ÖZDAŞ, SABRİ and AKDOĞAN, NEVZAT and AZİRET, MEHMET} } @ { ejgm71760, journal = {European Journal of General Medicine}, issn = {1304-3889}, address = {Sağlık Bilimleri Araştırmaları Derneği}, year = {2015}, volume = {9}, pages = {33 - 35}, doi = {}, title = {LAPAROSCOPİC SPLENECTOMY FOR SPLENIC CYST HYDATIC; CASE REPORT}, language = {tr}, key = {cite}, author = {SÖZEN, SELİM and ÖZDAŞ, SABRİ and AKDOĞAN, NEVZAT and AZİRET, MEHMET ...
Teaching Files with CT Medical Imaging and case studies on Anatomical Regions including Adrenal, Colon, Cardiac, Stomach, Pediatric, Spleen, Vascular, Kidney, Small Bowel, Liver, Chest | CTisus
The quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) induced immune responses in high-risk children and adolescents aged 1-17
List of causes of Left upper quadrant abdominal mass and Pain, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
A 32-year-old white man nonsmoker with a brief history of irritable colon disease and a recently available analysis of Crohns disease offered remaining upper quadrant stomach discomfort. splenic lesions in keeping with hemangiomas. A follow-up stomach computed tomographic (CT) check out demonstrated borderline splenomegaly BMS 433796 supplier with higher than 6 hypodense lesions in the spleen. At that right time, the liver organ enzymes had been within normal limitations, and a replicate US demonstrated mild and splenomegaly enlargement from the splenic lesions in comparison to the prior research. One month prior to the current demonstration, an stomach CT demonstrated an enlarged spleen calculating 15 cm around, and multiple hypodense lesions had been determined, but hadnt changed significantly in proportions (Shape 1). Furthermore, a positron emission tomographic (Family pet) scan was performed that demonstrated no improved fluorodeoxyglucose (FDG) localization related towards the splenic ...
Sharma SK, Dey AB, Agarwal N, Nagarkar KM, Gujral S. Tuberculosis: A rare cause of splenic abscess. Journal of Association of Physician India. 1999: 47(7): 740-1. PMID: 10778602. Agarwal N, Handa R, Acharya SK, Wali JP, Dinda AK, Aggarwal P. A study of autoimmune markers in Hepatitis C infection. Indian Journal of Medical Research. 2001:…
As soon as the prognosis of a splenic abscess has been made, the affected person have to be admitted to the hospital and handled. Remedy will depend on the.... ...
It is well known that the spleen is not an organ necessary for life, but in spite of its seemingly slight importance there are a surprisingly large number of pa
Teaching Files with CT Medical Imaging and case studies on Anatomical Regions including Adrenal, Colon, Cardiac, Stomach, Pediatric, Spleen, Vascular, Kidney, Small Bowel, Liver, Chest | CTisus
Non Hodgkin lymphoma with diffuse small hypoechoic liver lesions and multiple large vascularized hypoechoic splenic lesions and enlarged lymph nodes. ...
Of a cohort of 308 children with homozygous sickle cell disease diagnosed at birth, 89 experienced 132 clinically significant attacks of acute splenic sequestration (ASS) over a 10-year period. The age at first attack ranged from 3 months to 6 years. Survival curve analysis of the interval until first attack indicated a cumulative probability of 0.225 by 2 years, and 0.265 by 3 years, and 0.297 by 5 years of age. Thirteen events were fatal, 11 during the first attack, and all before transfusion could be instituted. Recurrences occurred in 49% of survivors of the first attacks, and there were diminishing intervals between subsequent events. Respiratory symptoms were associated with 52 of 132 events, but bacterial isolates on blood culture were less frequent, and ASS was not prevented by pneumococcal vaccine or penicillin prophylaxis. A high fetal hemoglobin level protected against attacks of ASS. A parental education program aimed at early diagnosis of ASS was followed by an increase in the incidence
Of a cohort of 308 children with homozygous sickle cell disease diagnosed at birth, 89 experienced 132 clinically significant attacks of acute splenic sequestration (ASS) over a 10-year period. The age at first attack ranged from 3 months to 6 years. Survival curve analysis of the interval until first attack indicated a cumulative probability of 0.225 by 2 years, and 0.265 by 3 years, and 0.297 by 5 years of age. Thirteen events were fatal, 11 during the first attack, and all before transfusion could be instituted. Recurrences occurred in 49% of survivors of the first attacks, and there were diminishing intervals between subsequent events. Respiratory symptoms were associated with 52 of 132 events, but bacterial isolates on blood culture were less frequent, and ASS was not prevented by pneumococcal vaccine or penicillin prophylaxis. A high fetal hemoglobin level protected against attacks of ASS. A parental education program aimed at early diagnosis of ASS was followed by an increase in the incidence
Unscramble nonparasitic, Unscramble letters nonparasitic, Point value for nonparasitic, Word Decoder for nonparasitic, Word generator using the letters nonparasitic, Word Solver nonparasitic, Possible Scrabble words with nonparasitic, Anagram of nonparasitic
Abstract In a prospective study of renal involvement in 100 consecutively hospitalized patients with hepatosplenic schistosomiasis mansoni, 15 exhibited persistent proteinuria of varying degree, which in 6 instances was accompanied by hypertension. Nine patients had the nephrotic syndrome. The most common glomerular lesion in this group was membrano-proliferative glomerulonephritis. Surgical biopsy obtained during splenectomy in 15 patients without clinical evidence of renal involvement showed glomerular lesions in 6 instances. Focal proliferative glomerulonephritis was the most common lesion in this group. The detection of silent glomerular lesions in patients with Schistosoma mansoni infection suggests that the glomerular alterations may precede clinical manifestations of renal disease.
This page includes the following topics and synonyms: Sickle Cell Anemia with Splenic Sequestration, Splenic Sequestration in Sickle Cell Anemia, Splenic Sequestration.
Aspergillosis is a serious infection particularly affecting the immunodeficient host. Its co-infection with tuberculosis and cytomegalovirus has not been reported before. Embolic events are well recognized with aspergillous endocarditis and aortitis. Splenic abscess is a rare serious complication of disseminated aspergillosis and is difficult to treat. We report the first case of multiple embolic events and splenic abscess in a patient with pulmonary aspergillosis and cytomegaloviral and tuberculous co-infection, without endocarditis or aortitis. Thirty-year-old male presented with fever and non-productive cough while on glucocorticoids for glomerulonephritis. He was found to have pulmonary aspergillosis and subsequently developed bilateral lower limb and cerebral fungal emboli and fungal abscess in the spleen. He had IgM and B cell deficiency and cytomegalovirus (CMV) and tuberculous co-infections. He recovered after prolonged course of antimicrobials, splenectomy and cessation of glucocorticoid
TY - JOUR. T1 - Hyposplenism. T2 - A comprehensive review. Part I: Basic concepts and causes. AU - William, Basem M.. AU - Corazza, Gino R.. PY - 2007/2. Y1 - 2007/2. N2 - Hyposplenism is not a rare condition and can complicate a remarkable number of illnesses. The two most time-honored diseases associated with the development of hyposplenism are sickle cell anemia and celiac disease. Hyposplenism is relatively easy to recognize by typical changes observed on the peripheral blood smear; including Howell-Jolly bodies, monocytosis, lymphocytosis, and increased platelet counts. Diagnosis can be confirmed by pitted RBC counts or 99Tc-labelled radiocolloid scan of the spleen; wherever available. Diagnosis needs to be made promptly to institute pneumococcal vaccination in a timely fashion and to recognize and treat bacterial infections promptly and aggressively because of the tendency of hyposplenic subject to develop fatal invasive disease. Overwhelming pneumococcal sepsis accounts for the major ...
OBJECTIVE: To determine the spectrum of presentation, treatment outcome and prognostic factors of splenic abscess in a tertiary care hospital. STUDY DESIGN: Case-series. PLACE AND DURATION OF STUDY: Department of General Surgery, the Aga Khan University Hospital, Karachi, from July 1988 to July 2007. METHODOLOGY: The records of 27 patients with splenic abscess, diagnosed from 1988 to 2007, were retrieved through ICD-10 coding system. The demographic data, physical and radiological findings, treatment modalities, bacteriology reports, morbidity and mortality were collected on a proforma. RESULTS: There were 12 males and 15 females with a mean age of 43.52+/-17.49 years. Common symptoms were fever (92.6%), abdominal pain (55.6%) and malaise (29.6%). Majority of patients (89%) had leukocytosis and 63% patients had associated diseases with which they were admitted. The most common pathogenic organism was Staphylococcus species and gram-negative rods. Ultrasound was used as a preliminary diagnostic modality,
The role of the spleen in the process of liver fibrosis in schistosomiasis still needs clarification. The aim of this Study was to assess the effect of splenectomy on serum levels of two markers of fibrosis, type IV collagen and TIMP-1, in patients with schistosomiasis mansoni. Twenty-four patients with hepatosplenic schistosomiasis mansoni participated in the study. Type IV collagen and TIMP-1 serum levels were measured preoperatively, and after 2 (POD-1) and 60 days (POD-2) of spleen removal. Before splenectomy, both type IV collagen and TIMP-1 serum levels were elevated in the majority of patients. After splenectomy, the levels of type IV collagen showed a significant decrease in relation to the preoperative values both in POD-1 (median pre-splenectomy: 143.7 ng/ml versus 77.01 ng/ml p = 0.04) and POD-2 (103.3 ng/ml; p = 0.015). Serum levels of TIMP-1 also showed a significant decrease in relation to the preoperative values both in POD-1 (pre-splenectomy: 585.9 ng/ml versus 196.4 ng/ml; p = ...
Abstract. We investigated the serum and urine chemokine levels of patients with schistosomal mansoni glomerulonephritis. This cross-sectional study was conducted in the Southeast of Brazil. Overall, 160 subjects were enrolled and divided into five groups: 1) hepatosplenic schistosomiasis with renal disease (N = 12); 2) hepatosplenic schistosomiasis without renal disease (N = 68); 3) hepatointestinal schistosomiasis (N = 27); 4) glomerulopathy caused by other diseases (N = 22); and 5) healthy controls (N = 31). The patients with microalbuminuria > 30 mg in 24 hours were considered to have renal disease. The sera and urine chemokines CCL2, CCL3, CCL5, CCL11, and CXCL8 were measured using an enzyme-linked immunosorbent assay test. A similar profile was observed between the patients with schistosomal glomerulopathy and the patients with glomerulopathy caused by other diseases, with the exception of serum CCL2 ≤ 634.3 pg/mL. In cases with sera CCL2 > 634.3 pg/mL, the diagnosis of schistosomal
Splenic cysts are very rare lesions, most of them being parasitic systs. Nonparasitic cysts are uncommon. We report a case of young female who presented with mass and pain abdomen. Ultrasound examination revealed splenic syst. The diagnosis of epidermoid cyst was made based on characteristic lining on histopathological examination ...
Background The optimal treatment of nonparasitic liver cysts is still a topic of debate. Only symptomatic cysts are being considered as requiring treatment. Aim of this study is to evaluate our...
Teaching Files with CT Medical Imaging and case studies on Anatomical Regions including Adrenal, Colon, Cardiac, Stomach, Pediatric, Spleen, Vascular, Kidney, Small Bowel, Liver, Chest | CTisus
Chair: Michael Awad, MD, PhD Faculty: Jeffrey Blatnik, MD; Amber Traugott, MD; and Adnan Alseidi, MD Program Outline: -Welcome and Overview: Michael Awad, MD, PhD -Esophagus, Stomach, Obesity: Michael Awad, MD, PhD -General Abdomen, Hernia, Spleen: Jeffrey Blatnik, MD -Colorectal & Anal Disease: Amber Traugott, MD -Small Intestine, Biliary Disease, Flexible Endoscopy: Adnan Alseidi, MD. ...
Evaluation of WGA and Concanavalin A (Con A) lectin as biomarkers of hepatosplenic schistosomiasis in human biopsies with no evidence of egg-granuloma system ...
Question - I am having left upper quadrant abdominal pain, what could this problem be ?. Ask a Doctor about diagnosis, treatment and medication for Diarrhea, Ask a Gastroenterologist, Surgical
Gamna Gandy nodules also known as splenic siderotic nodules and fibrosiderotic nodules, are small focal deposits of iron and calcium within fibrous tissue and elastic fibers in spleen resultiing in tiny nodules of less than one millimeter in size...
Sir Benjamin C. Brodie,20 in 1846, described seeing a young lady with a cystic tumor of the upper right abdomen which disappeared after aspiration of 2 pt. of c
Administer PPSV at least 8 weeks after the last dose of PCV to children aged 2 years or older with certain underlying medical conditions like anatomic or functional asplenia (including sickle cell disease), HIV infection, cochlear implant or cerebrospinal fluid leak ...
Thrombocytopenia is traditionally taught with distinguishing between a bone marrow disorder, ruling out splenic sequestration, or peripheral destruction.. Discussion points: Discuss the differential diagnosis of thrombocytopenia.. Decreased production:. ...
A medical method comprises the steps of scanning a predetermined internal organ of a patient to collect individualized dimensional data about the organ, digitizing the data, and automatically storing encoded structural dimensions of the organ at different times. Dimensions of the organ are automatically compared with previously stored dimensions to determine changes in the dimensions. A cognizable signal is automatically generated, at a remote facility or at the person of the patient, upon a determination that dimensions of the organ have changed so as to indicate a dangerous condition of the patient, such as a ruptured splenic hematoma or a ruptured aneurysm.
PETROIANU, Andy; PEREIRA, Thiago Costa; OLIVEIRA, Teon Augusto Noronha de and BARBOSA, Alfredo José Afonso. Assessment of different conservative methods of the spleen for treatment of splenic incisional lesion in the dog. Rev. Col. Bras. Cir. [online]. 2004, vol.31, n.6, pp.364-367. ISSN 0100-6991. http://dx.doi.org/10.1590/S0100-69912004000600006.. BACKGROUND: The treatment morbimortality of splenic trauma is related to the size of the lesion and to the surgeon experience. Our purpose was to verify the splenic recovery after conservative methods of treating incisional splenic lesions in dog. METHODS: Twenty male mongrel dogs weighing between 7 and 12 kg were submitted to a 3 cm deep and 5 cm long longitudinal incisions of the spleen under sodium pentabarbital anesthesia. The dogs were randomly divided into three groups: Group 1 (n = 10) - without repair (control); Group 2 (n = 5) - only splenic suture; Group 3 (n = 5) - splenic suture and omentoplasty. Repairs were performed by using running ...
With the help of international collaborators, the Rockefeller researchers sequenced the exomes of 33 asplenic patients from 23 families (kindreds). Then they rounded up the usual suspects for a very rare disease: a mutation not in public databases, overrepresented among the families but extremely rare or non-existent in control exomes, and with a large effect. They werent looking for a relatively meaningless SNP that denotes a vague association, but a hardcore nonsense mutation that shortens or even deletes the gene and protein, or a single-base change that alters the encoded amino acid (a nonsynonymous change ...
The spleen is an important component of the lympho-hematopoietic complex system, playing a relevant role in the defense against infections. Patients wit..
Peliosis is a pathological entity characterized by the gross appearance of multiple cyst-like, blood-filled cavities within solid organs. It is traditionally thought that peliosis exclusively develops in organs belonging to the mononuclear phagocytic system (liver, spleen, bone marrow, and lymph nodes) [3]. However, a paucity of studies indicate that other organs such as the lungs, parathyroid glands, and kidneys may be affected too [4-6]. Isolated splenic peliosis was unreported until 1978 [11]. Until then it was thought to occur only in association with the more common peliosis hepatis[7].. Many aetiological agents have been postulated. Drugs and toxins including chronic alcoholism, corticosteroids, oral contraceptives, tamoxifen, azathioprine and androgens have been linked with the occurrence of peliosis [2, 3, 9, 14]. The latter may help to explain why the disease appears to be more common in males [2]. The now-discontinued x-ray contrast medium Thorotrast, and vinyl chloride have also been ...
Abstract:. Primary splenic lymphoma is defined as generalized lymphoma with splenic involvement as the dominant feature. Primary splenic lymphoma is an infrequent disease. It comprises less than 1% of the all malignant lymphoma. We present a case of 55 years old male with fever, pain and lump in abdomen of 1 month duration. The purpose of this paper is to report a rare occurrence of primary splenic lymphoma and to demonstrate the possibility of it misdiagnosed as splenic abscess clinically and on imaging.. ...
Hepatic and splenic lesions were developed in mice of both sexes following their exposure to cercariae of Schistosoma mansoni (70 cercariae / animal). After 12 weeks of infection, the liver showed the formation of typical egg granuloma infiltered with abundant bilharzial pigments, meanwhile, paragranuloma hepatocytes displayed abnormal alterations. However, no egg lesions were observed in the spleen of infected mice and the only detectable change was distortion of splenic parenchyma with deposited bilharzial pigments. The present investigation was extended to include the effect of praziquantel administration on the liver and spleen of non infected and schistosome infected mice. The study revealed that, the drug induced areas of focal necrosis in the liver, whereas it was found to have no marked effect on the spleen of non infected mice. In addition, the drug administration to schistosome infected mice circumvented induced lesions in both liver and spleen ...
A child may be asplenic for anatomic or functional reasons. Anatomic reasons include: (1) congenital asplenia, which can be isolated, or part of Ivemark syndrome, which is associated with cardiovascular defects and heterotaxy and (2) splenectomy. Splenectomy may be performed for various reasons. In children, the most common reasons are trauma-associated splenic rupture, malignancy, hypersplenism, and splenomegaly associated with persistent anemia and/or thrombocytopenia.2 Functional asplenia results from having an anatomically intact but poorly working spleen. There are various conditions that can cause functional asplenia, including sickle cell disease (Table 57-1). Some of the mechanisms leading to functional asplenia include infarction, infiltration, and impaired phagocyte function.2-4 ...
p,,strong,Background:,/strong, Total splenectomy, exposes children to the high risk of overwhelming postsplenectomy infections (OPSI). To avoid these adverse consequences, partial splenectomy has long been practiced for thalasseemia in children. It has been reported that the partial splenectomy keeps the child immunologically competent, hematologically stable with minimum blood transfusion and makes their life more comfortable in comparison to total splenectomy.,/p,,p,,strong,Objectives:,/strong, To compare the results of partial and total splenectomy.,/p,,p,,strong,Methodology:,/strong, This prospective interventional comperative study was done in the department of Pediatric Surgery, BSMMU from 2010 to 2012. Children who underwent partial splenectomy were considered as the case and who underwent total splenectomy as the control. Number of blood (RCC) transfusions (ml/ kg/year), Peripheral blood film (Hb%, WBC count, platelet count, Howell-Jolly body, serum bilirubin), volume of liver (ml), ...
The laparoscopic intra-operative findings were splenic infarction, abscess in the lower part of the spleen and widespread inflammatory adhesions between spleen, greater omentum and parietal peritoneum. We performed laparoscopic splenectomy using Ligasure as device for dissection and vessels sealing. The estimated blood loss was 230 mL. The postoperative course was uneventful, no blood transfusion was needed and the patient was discharged on the 12th postoperative day. Histopathological examination confirmed infarction of the spleen and the presence of multiple abscesses. ...
TY - JOUR. T1 - Spontán lépruptura idiopathiás pulmonalis fibrosisban. AU - Erzsébet, Szolnoki. AU - Balázs, Dezso. AU - Mária, Szilasi. PY - 2008/7/1. Y1 - 2008/7/1. N2 - INTRODUCTION - Splenic peliosis is a pathological entity; it is only mentioned in case reports in the literature. CASE REPORT - A 61-year-old man with hypertension and diabetes mellitus presented with effort dyspnoe that was subsequently found to be due to idiopathic pulmonary fibrosis by histological examination. During steroid therapy, a spontaneous splenic rupture developed, which the patient fortunately survived. There was no need for splenectomy, but the clinical course suggested splenic peliosis. CONCLUSION - In this case, splenic rupture was associated with idiopathic pulmonary fibrosis, a constellation that has not yet been reported. Nevertheless, it was an isolated rupture, with no similar haemorrhagic lesion of other parenchymal organs. In view of the literature data, beside primary disease steroid therapy and ...
F-FDG PET/CT in the diagnosis of occult bacterial infections in children. Rosal, Teresa; Goycochea, Walter; Méndez-Echevarría, Ana; García-Fernández de Villalta, Marta; Baquero-Artigao, Fernando; Coronado, Mónica; Marín, Maria; Albajara, Luis // European Journal of Pediatrics;Aug2013, Vol. 172 Issue 8, p1111 The role of F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) in the diagnosis and follow-up of infectious diseases has expanded recently. The aim of this report is to communicate our experience regarding its role in the diagnosis and management of occult... ...
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Tumor bed brachytherapy with a mesh implant is a practical technique to improve tumor control and warrants further investigation. In this Review, I question whether latent persistent pathogens might 30 day cialis free trial be key factors that drive this imbalance and whether they determine the extent of age-associated immune deficiency. As many tumors are established through the evasion of infiltrating immune-cell clearance, the lessons learned in MCC may be broadly relevant to many cancers. Improving rural health: the lessons of Mississippi and canada pharmacy cialis Tanzania. Interleukin (Il)-12, Il-5 and total IgE in hepatosplenic schistosomiasis with or without asthma. Nature of hardness evolution in 5 mg cialis over the counter at walmart nanocrystalline NiTi shape memory alloys during solid-state phase transition. Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease. Assessments included response rate, ...
Hepatosplenic Amyloidosis & Iritis Symptom Checker: Possible causes include Ankylosing Spondylitis & Psoriatic Arthritis & Ulcerative Colitis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
The British Society for Haematology is registered in England and Wales as a Company Limited by Guarantee, No 2645706 and as a Charity, No 1005735 Registered Office and correspondence address: 100 White Lion Street London N1 9PF. Phone: 020 7713 0990 ...
The most common of such causes is malignant neoplasia (eighty% of scenarios in a single research) and the majority of People conditions are hemangiosarcoma (88%). More malignant tumors can involve mesothelioma, pheochromocytoma and hepatic metastasis from other abdominal malignancies. The most common non-malignant cause is actually a ruptured splenic hematoma which in fact has a great prognosis with splenectomy alone. Homeowners should typically make immediate selections with regards to stabilization, treatment and surgery for their pet. Consequently, it is vital to inform homeowners of your likelihood of their pet acquiring malignant neoplasia along with the treatment alternatives in addition to the overall weak prognosis related with hemangiosarcoma (HSA ...
I was admitted for Chest congestion on the 29th of Oct 08. Within a few hours I lost consciousness and the doctors for the next ten days treated me for TB and Jaundice. On the 11th day a biopsy of splenic lesion confirmed that I am suffering from 4th stage NHL. I was administered chemotherapy and the second R-CHOP was given on the 14th day. After two chemos I was discharged and subsequently visited the hospital on the days of the next four chemos. After the 6th chemo I underwent a CT Scan
One of the purposes of the spleen is to produce substances known as antibodies that help protect you against certain types of bacteria, the most common of which is one that causes pneumonia. People without spleens or who have inadequately functioning spleens are unable to produce the antibodies normally. To protect against infection, patients at the University of California, Davis Medical Center who have suffered injuries to their spleen are routinely given a vaccine called Pneumovax®. With this study, we hope to learn more about patients whose spleen has been removed or made at least partially nonfunctional by the injury, and their ability to protect themselves with antibodies against the bacteria ...
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The section diagnosing parasitic and nonparasitic diseases is designed as a true diagnostic tool, illustrated by more than 900 color photographs and numerous illustrations to aid the observation of the plants. This tool can easily be used as the symptoms are grouped under simple headings. It is also educational and should ultimately enable the reader to learn the many factors needed to establish a reliable diagnosis. The book draws the attention of prospective readers to the benefits of using the diagnostic method of diagnosing diseases by taking into account the symptoms that characterize them. Once identification is complete, the reader will find a detailed description for the majority of pests and pathogens in the third section, principles characteristics of pathogenic agents and methods of control. This section details the distribution and impact on tomato growing in the world, the main symptoms produced, and their morphological and biological characteristics. With this knowledge, readers ...
The Goopolla Spleen is a Resource extracted from Goopolla, saltwater fish commonly found on coastlines near Cetus. Goopolla Spleens are acquired by cutting up Goopolla caught through Fishing. Go to Fisher Hai-Luk in Cetus, select the desired amount of Goopolla available, and select the "Cut...
See Bornholm disease.) Tidy, H. (5 July 1952). "Banti's Disease and Splenic Anaemia". Br Med J. 2 (4774): 1-4. doi:10.1136/bmj. ... See Ayerza's disease.) Tidy, H. (January 1950). "Glandular Fever: Infectious Mononucleosis". Postgrad Med J. 26 (291): 9-15. ... Tidy, H. (4 June 1949). "Ayerza's Disease, Silicosis, and Pulmonary Bilharziasis". Br Med J. 1 (4613): 977-978. doi:10.1136/bmj ... Tidy, H. (24 November 1951). "Bornholm Disease". Br Med J. 2 (4742): 1277. doi:10.1136/bmj.2.4742.1277. PMC 2070803. ( ...
Splenic function in sickle-cell diseases. Clinical Science. vol. 65, p. 297-302. SANTOS, S. E. B., RIBEIRO-DOS-SANTOS, A. K. C ... who is active in the fields of hereditary diseases of the blood (hemoglobins, clotting, thrombosis), molecular basis of cancer ... returned to Brazil and started a research group with a major scientific interest in the genetic bases of hematological diseases ... for the medical genetic studies that compare these populations and for the understanding of the hereditary diseases. ...
Primary diseases of the spleen are splenic torsion and splenic tumors. Splenic torsion occurs when the spleen twists along the ... Perkins, Ranetta (2009). Splenic Torsion in a 3 year old male intact Greater Swiss Mountain dog (Report). Retrieved October 14 ... Symptoms of splenic torsion include lethargy, abdominal distension and pale mucous membranes. One theory for the development of ... CHD is among the principal orthopedic diseases in the Greater Swiss Mountain Dog; it is rarely severe and crippling. Unless x- ...
... connective tissue diseases, thyrotoxicosis, Addison's disease, splenomegaly with splenic sequestration of granulocytes. ... "Impaired Control of Epstein-Barr Virus Infection in B-Cell Expansion with NF-κB and T-Cell Anergy Disease". Frontiers in ... Chagas disease) chronic intracellular bacterial infections such as tuberculosis or brucellosis chronic lymphocytic leukemia ... also known as BENTA disease) Causes of relative lymphocytosis include: age less than 2 years; acute viral infections; ...
Splenic-flexure syndrome or "Payr's disease" is named after a condition he described. Payr's disease is constipation due to ...
"Acute splenic sequestration in homozygous sickle cell disease: Natural history and management". The Journal of Pediatrics. 107 ... Between 1982 and 1987, Emond attained the Doctor of Medicine with a thesis titled: The Spleen in Sickle Cell Disease in ... Emond, Alan M. (1 November 1980). "Priapism and Impotence in Homozygous Sickle Cell Disease". Archives of Internal Medicine. ...
These include Siberian plague, Cumberland disease, charbon, splenic fever, malignant edema, woolsorter's disease, and even la ... If the disease is fatal to the person's body, though, its mass of anthrax bacilli becomes a potential source of infection to ... A rare disease, human anthrax is most common in Africa and central and southern Asia. It also occurs more regularly in Southern ... It was shown to cause disease by Robert Koch in 1876 when he took a blood sample from an infected cow, isolated the bacteria, ...
... autoimmune liver disease and its treatment with corticosteroids, and the use of liver biopsy in the diagnosis of liver disease ... Obituary, The Guardian, 19 January 2002 Sherlock, S. P. V.; Learmonth, J. R. (1942). "Aneurym of the splenic artery: With an ... Diseases of the Liver and Biliary System, 11th edition. S. Sherlock & J. Dooley (ISBN 978-0-632-05582-1) "Professor Dame Sheila ... The liver unit that she set up at the Royal Free Hospital became the centre for both research into liver disease and the ...
Splenic involvement is signified by adding "S" to the stage. The inclusion of "bulky disease" is signified by "X". ... announced in August 2015 that he was diagnosed with Hodgkin's disease. He later died of the disease in October 2015.[50] ... heart disease, or lung disease over the subsequent decades.[9] ... in which he called the disease "Hodgkin's disease" in honor of ... The choice of treatment depends on the age, sex, bulk and the histological subtype of the disease.[citation needed] Adding ...
... splenic and gastric diseases, pediatrics, rheumatoid arthritis, and ophthalmology. The library has a collection of over 500,000 ... Institutions have been established in this university in the studies of Zhang Zhong-jing's theories, AIDS, hepatic diseases, ...
Notes on the large death rate among Australian sheep, in country infected with Cumberland Disease, or splenic fever, Journal ... In 1906 he traveled to Canada, where he demonstrated that the equine disease, dourine is caused by the parasite trypanosoma ... Notes on a spontaneous disease among Australian rabbits, Journal and Proceedings of the Royal Society of New South Wales, 1891 ...
... also thought to promote the development of splenic enlargement and extramedullary hematopoiesis in human myelofibrosis disease ... About half of afflicted individuals have various birth defects.[10] The disease is regarded as a uniformly genetic disease ... D218Y: familial disease similar to but more severe that the disease cause by G209S and D218G mutations. ... and the disease caused by R216W and R216Q mutations in GATA1. The GATA1 mutation-related disease resembles the one caused by ...
Autoimmune diseases may also go into remission after treatment of HCL. This disease is rare, with fewer than 1 in 10,000 people ... such as Splenic marginal zone lymphoma or B-cell prolymphocytic leukemia. The diagnosis can be confirmed by viewing the cells ... As a result, disease status can be monitored by measuring changes in the amount of IL-2R in the blood serum. The level ... While the disease can appear at any age, the median age at diagnosis is over 70. Similar to B-cell prolymphocytic leukemia ("B- ...
Fulminant disease course of immunocompromised people are rare. Splenic rupture is rare. Myocarditis and pericarditis are rare. ... Mononucleosis is sometimes accompanied by secondary cold agglutinin disease, an autoimmune disease in which abnormal ... when the disease produces few or no symptoms. In young adults, the disease often results in fever, sore throat, enlarged lymph ... "the kissing disease". Filatov's disease at Who Named It? "About Epstein-Barr Virus (EBV)". CDC. January 7, 2014. Archived from ...
Disseminated HS (including MH) is not readily treated surgically, since even in the splenic form, early metastasis to the liver ... Histiocytic diseases in dogs are a group of diseases in dogs which may involve the skin, and which can be difficult to ... The disease course may be punctuated by remissions and relapses, which may occur spontaneously especially early in the disease ... The disease course in these cases extended over several months. Spread beyond lymph nodes to lung has also been observed in ...
Erwin Payr (1871-1946), surgeon, eponymn of Splenic-flexure syndrome or "Payr's disease" Meinhard von Pfaundler (1872-1947), ... pediatrician, interest in the diathetic aspects of disease Arnold Durig (1872 - 1961) Austrian physiologist, investigated ...
Splenic involvement is signified by adding "S" to the stage. The inclusion of "bulky disease" is signified by "X". ... announced in August 2015 that he was diagnosed with Hodgkin's disease. He later died of the disease in October 2015.[74] ... heart disease, or lung disease over the subsequent decades.[11] ... in which he called the disease "Hodgkin's disease" in honor of ... "Mediterranean Journal of Hematology and Infectious Diseases. 6 (1): e2014048. doi:10.4084/mjhid.2014.048. ISSN 2035-3006. PMC ...
"Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation ... Caroli disease, choledochal cyst, cholestasis, congenital cytomegalovirus disease, congenital herpes simplex virus infection, ... The influence of age differs according to the disease etiology-i.e., whether biliary atresia is isolated, cystic (CBA), or ... The biliary atresia phenotype caused by congenital aflatoxicosis in GST M1 deficient neonates is named Kotb disease. Syndromic ...
These include infectious diseases, medical procedures such as colonoscopy, haematological diseases, medications, and pregnancy ... Splenic rupture is usually evaluated by FAST ultrasound of the abdomen. Generally this is not specific to splenic injury; ... American Association for the Surgery of Trauma Organ Injury Scaling: Splenic Injury Grading Because a splenic rupture permits ... "613 cases of splenic rupture without risk factors or previously diagnosed disease: A systematic review". BMC Emergency Medicine ...
In sickle cell disease, repeated splenic infarctions lead to a non-functional spleen (autosplenectomy). Any factor that ... Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot. In one ... Splenic infarction can be induced for the treatment of such conditions as portal hypertension or splenic injury. It can also be ... Other causes of splenomegaly (for example, Gaucher disease or hemoglobinopathies) can also predispose to infarction. Splenic ...
The disease shows a distinct sinusoidal pattern of infiltration which spares the splenic white pulp and hepatic portal triads. ... The cell of origin for this disease is an immature cytotoxic T-cell clonally expressing the γδ T-cell receptor. The disease is ... They presented with a very aggressive disease course, and all but one died. The Food and Drug Administration required changes ... The majority of cases occurred in patients with inflammatory bowel disease. Adolescents and young adult males were most ...
... degenerescence book type Spirochetes disease Spirurida infections Spleen neoplasm Splenic agenesis syndrome Splenic flexure ... This is a list of diseases starting with the letter "S". Diseases Alphabetical list 0-9 A B C D E F G H I J K L M N O P Q R S T ... hemangiomas Suriphobia Susac syndrome Sutherland-Haan syndrome Sutton disease II Sutton disease II Sweeley-Klionsky disease ... disorder Schamberg's disease Scheie syndrome Schereshevskij Turner Scheuermann's disease Schimke syndrome Schindler disease ...
... and tumor necrosis factor alpha in splenic Gaucher cells (engorged macrophages). Gaucher disease is suggested based on the ... Zealand radio and television personality Sphingolipidoses Niemann-Pick disease Fabry disease Tay-Sachs disease Krabbe disease ... Gaucher's disease is the most common of the lysosomal storage diseases. It is a form of sphingolipidosis (a subgroup of ... Type II Gaucher's disease shows no particular preference for any ethnic group. Type III Gaucher's disease is especially common ...
The final chapter is of Smith and the doctor discussing disease as a battle; the doctor pronounces Smith's victory. They begin ... one example being medical research on splenic fever in cattle. He functions primarily as a friend to John Smith. Mrs. Rundle, ... Left to his own devices alone again, Smith expresses hopes for Lamarckism: the eradication of disease and eventually of the ... He hopes for the near eradication of disease and criminal activity through invention and human moralistic evolution over time. ...
Functional asplenia occurs when splenic tissue is present but does not work well (e.g. sickle-cell disease, polysplenia) -such ... Due to underlying diseases that destroy the spleen (autosplenectomy), e.g. sickle-cell disease. Celiac disease: unknown ... Furthermore there is a deficiency of other splenic cells e.g. splenic macrophages. This combined with the lack of B cells can ... 2007). "Partial splenic embolization in children with hereditary spherocytosis". European Journal of Haematology. 80 (1): 76-80 ...
Hemosuccus pancreaticus is associated with pancreatitis, pancreatic cancer and aneurysms of the splenic artery. Angiography may ... Pancreatic diseases are diseases that affect the pancreas, an organ in the human body located in the abdomen. The pancreas ... The most common pancreatic disease is pancreatitis, an inflammation of the pancreas which could come in acute or chronic form. ... In a study of 2,832 patients without pancreatic disease, 73 patients (2.6%) had cysts in the pancreas. About 85% of these ...
Pediatric patients with sickle cell disease and beta thalassemia experience multiple splenic infarcts, resulting in splenic ... However, late adolescent or adult patients in this group who maintain splenic function may develop splenic sequestration crisis ... Splenic sequestration crisis can only occur in functioning spleens which may be why this crisis is rarely seen in adults. ... Up to 30% of these children may develop SSC with a mortality rate of up to 15%. This crisis occurs when splenic vaso-occlusion ...
... and/or a blood serum albumin levels of less than 3.5 g/dL are likely to have more an aggressive disease course and a shorter ... Splenic marginal zone lymphoma (SMZL) is a type of cancer (specifically a lymphoma) made up of B-cells that replace the normal ... October 1995). "Splenic marginal zone lymphoma: a distinctive type of low-grade B-cell lymphoma. A clinicopathological study of ... Arcaini, L. (2006). "Splenic marginal zone lymphoma: a prognostic model for clinical use". Blood. 107 (12): 4643-4649. doi: ...
... and splenic rupture. Some develop coronary artery or valvular heart disease. In a longitudinal natural history study, nearly 20 ... Type C is the most common form of the disease Type C2 is a rare form of the disease. Niemann-Pick disease type D (or Nova ... orphan designation for HPbCD for the treatment of Niemann-Pick disease, type C. Niemann-Pick disease, type C Gaucher's disease ... Niemann-Pick disease, SMPD1-associated, which includes types A and B Niemann-Pick disease type A: classic infantile Niemann- ...
Splenic sequestration is a problem with the spleen that can happen in people who have sickle cell disease. ... Splenic sequestration happens when a lot of sickled red blood cells become trapped in the spleen. The spleen can enlarge, get ... If you have a baby or young child who has sickle cell disease, you will check your childs spleen to see if its larger than ... Splenic sequestration causes sudden and severe anemia, with symptoms of sudden weakness, pale lips, rapid breathing, excessive ...
Due to the limited and nonspecific symptoms, splenic hydatid disease has a long latency period. Commonly it is diagnosed as an ... A splenic hydatid cyst should be treated surgically due to the risk of rupture. Albendazol therapy is the treatment of choice ... 1. Polat P, Kantarci M, Alper F, Suma S, Koruyucu MB, Okur A. Hydatid disease from head to toe. RadioGraphics. 2003; 23: 475-49 ... Findings: Because the residing area was an endemic hydatid disease zone, a primary spleen hydatid cyst was suspected. Enzyme- ...
Sickle cell disease is an inherited blood disorder. Children are born with the condition. It affects a part of the red blood ... See Helping Hand HH-I-221, Sickle Cell Disease and Fever.). Spleen crisis (Splenic Sequestration). Sickle cells can block the ... Sickle cell disease is an inherited blood disorder. Children are born with the condition. It affects a part of the red blood ... The spleen usually does not work well after 4 to 6 months of age in children who have sickle cell disease. This makes children ...
Diseases : Celiac Disease, Ectopic Calcification, Splenic Calcifications, Splenic Diseases. Problem Substances : Gluten, Wheat ... 3 Abstracts with Splenic Diseases Research. Filter by Study Type. Animal Study. ... Celiac disease with multiple foci of calcification in the spleen has been reported.Dec 03, 2010. ... For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to ...
Vascular Pathology: Vascular Disease: Ruptured Splenic Artery Aneurysm. Vascular Pathology: Vascular Disease: Ruptured Splenic ... Previous Vascular Pathology: Vascular Disease: Aneurysms of Basilar and Coronary Arteries * Next Vascular Pathology: Infectious ... Autopsy revealed a ruptured splenic aneurysm, with a 3Ã?,Ã?,½ pint haemoperitoneum. No other vascular anomalies were present. ...
Splenic sequestration is a problem with the spleen that can happen in people who have sickle cell disease. Splenic ... Splenic sequestration is a problem with the spleen that can happen in people who have sickle cell disease. ... Splenic sequestration happens when a lot of sickled red blood cells become trapped in the spleen. The spleen can enlarge, get ... Splenic sequestration causes sudden and severe anemia, with symptoms of sudden weakness, pale lips, rapid breathing, excessive ...
Is Splenic Flexure Mobilization Necessary in Laparoscopic Anterior Resection? Another View Diseases of the Colon & Rectum55(11 ... Is Splenic Flexure Mobilization Necessary in Laparoscopic Anterior Resection? Another View. Ludwig, Kirk A. M.D.; Kosinski, ... Is Splenic Flexure Mobilization Necessary in Laparoscopic Anterior Resection? * Use of Preoperative MRI to Select Candidates ... Home , November 2012 - Volume 55 - Issue 11 , Is Splenic Flexure Mobilization Necessary in Laparoscopic An... ...
Depletion of immunoglobulin M memory B cells is associated with splenic hypofunction in inflammatory bowel disease.. Di ... our aim was to verify whether IgM memory B cells mirror the reduced splenic function in Crohns disease and ulcerative colitis ... In inflammatory bowel disease patients circulating IgM memory B cells were significantly lower than in control subjects. We ... B cells are reduced in inflammatory bowel disease patients and this defect seems to be related to the impairment of splenic ...
Thyroid Disease, Dermatitis Herpetiformis, and Splenic Atrophy. Ann Intern Med. 1985;103:157. doi: 10.7326/0003-4819-103-1-157_ ... Thyroid Disease, Dermatitis Herpetiformis, and Splenic Atrophy PETER N. FOSTER, B.M., B.CH. ... The authors do not appear to have considered the possible role of associated splenic atrophy, which occurs in up to one third ... have recently reported a significant but unexplained association between clinical thyroid disease, thyroid autoantibodies, and ...
Simple Method of Assessing Splenic Function in Coeliac Disease. G. R. Corazza, A. W. Bullen, R. Hall, P. J. Robinson, M. S. ... Simple Method of Assessing Splenic Function in Coeliac Disease. G. R. Corazza, A. W. Bullen, R. Hall, P. J. Robinson, M. S. ... Simple Method of Assessing Splenic Function in Coeliac Disease Message Subject (Your Name) has forwarded a page to you from ... 6. The incidence of splenic hypofunction in coeliac patients may be related to the duration of untreated disease. ...
Crohns disease with inflammatory splenic granuloma Message subject: (Your Name) has forwarded a page to you from Journal of ...
Seventy-seven EDTA-blood and 64 splenic tissue samples were collected from 78 dogs with splenic disease in a Mediterranean area ... Molecular detection of vector-borne pathogens in blood and splenic samples from dogs with splenic disease. ... Concurrent diseases and conditions in dogs with splenic vein thrombosis. J Vet Intern Med. 2010;24:1298-304.View ArticlePubMed ... in dogs with splenic disease. J Vet Intern Med. 2011;25:1284-91.View ArticlePubMedGoogle Scholar. ...
Untreated mice showed signs of disease, had high blood and spleen-counts, whereas mice treated with the non-therapeutic dose ... To associate these infectious foci to invasive pneumococcal disease during pneumonia, we analysed spleens in a baboon pneumonia ... Recently, we have shown that experimental murine sepsis is preceded by intracellular replication within splenic macrophages ( ... Ercoli Nat Microbiol 2018), which shed into the bloodstream initiating invasive disease. Here we aimed to investigate a role ...
Global: Cancer diseases Anatomical: Immune diseases See all MalaCards categories (disease lists) ... The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... MalaCards integrated aliases for Splenic Manifestation of Leukemia:. Name: Splenic Manifestation of Leukemia 12 15 ... MalaCards based summary : Splenic Manifestation of Leukemia, is also known as splenic leukemia. An important gene associated ...
The disease-free interval was more than 5 years after the additional postoperative chemotherapy. She did not complain of any ... Solitary splenic metastasis of epithelial ovarian cancer is rare in patients with post-treatment ovarian cancer with long ... We report a case of a 62-year-old Japanese woman who presented with elevated serum cancer antigen 125 due to a solitary splenic ... Laparoscopic splenectomy was performed as tertiary cytoreduction with a diagnosis of a solitary splenic metastasis. Her ...
Splenic Diffuse Red Pulp Small B-Cell Lymphoma (SDRPL) Categories: Blood diseases, Immune diseases, Rare diseases ... Global: Rare diseases Anatomical: Blood diseases Immune diseases See all MalaCards categories (disease lists) ... Diseases related to Splenic Diffuse Red Pulp Small B-Cell Lymphoma via text searches within MalaCards or GeneCards Suite gene ... The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
Myoidangioendotheliomas can be managed with open or laparoscopic splenectomy with minimal risk of recurrent disease. Herein, we ... Splenic myoid angioendothelioma mimicking metastatic disease in an 8-year-old with Stage IV Wilms tumour ... Shah, A., Dragos, L., Kane, T., & Petrosyan, M. (2018). Splenic myoid angioendothelioma mimicking metastatic disease in an 8- ... Myoidangioendotheliomas can be managed with open or laparoscopic splenectomy with minimal risk of recurrent disease. Herein, we ...
Splenic infarcts fortunately are rare events, caused by occlusion of the splenic artery or one of its branches, which results ...
Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms ... Splenic Diseases. On-line free medical diagnosis assistant. ... Splenic Diseases. 0.35 hz Relief Lymphodema, Lymphatic Diseases ... Histopathology Spleen --Gaucher disease. ... Tay Sachs Disease, Gaucher Disease, Neiman .... youtube.com - Tue, 01 May 2007 12: ... Splenic Diseases (enlarged Spleen). Lymphedema , see further freq.: 0.12 hz, 0.35 hz, 0.93 hz .... youtube.com - Sat, 27 Dec ...
Disease progress can be halted and blocked at the molecular level. Mutant Npc1 (Npc1−/−) mice showed increased spleen weight ... Also, FACS analyses showed that the increased number of splenic myeloid cells in Npc1−/− mice was normalized by the treatment. ... The mechanisms of splenomegaly and alterations of lipid metabolism-related genes in NPC1 disease are still poorly understood. ... Niemann-Pick disease type C1 (NPC1) is an autosomal-recessive lipid-storage disorder with an estimated minimal incidence of 1/ ...
Guda Pippali is very old Ayurvedic formulation for treatment of Splenic Disease. It is also effective in chronic fever, cough ... Guda Pippali For Splenic Disease. Anupama May 23, 2014 May 23, 2014. ... It is one of the key ingredient of Guda Pippali which is used to treat many diseases. Long pepper is used to treat a variety of ... Guda Pippali is Ayurvedic medicine referenced from Bhaishajyaratnavali, and is indicated in pleeharogadhikar/spleenic diseases ...
... , Splenic Sequestration in Sickle Cell Anemia, Splenic Sequestration. ... However, less severe forms of Sickle Cell Disease can occur in adulthood ... Sickle Cell Anemia with Splenic Sequestration Aka: Sickle Cell Anemia with Splenic Sequestration, Splenic Sequestration in ... Search other sites for Sickle Cell Anemia with Splenic Sequestration NLM Pubmed Google Websites Google Images QuackWatch ...
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Splenic Vein / Thrombosis / Female / Humans / Celiac Disease ... Full text: Available Index: IMSEAR (South-East Asia) Main subject: Splenic Vein / Thrombosis / Female / Humans / Celiac Disease ... Occult celiac disease presenting as splenic vein thrombosis. Occult celiac disease presenting as splenic vein thrombosis. ...
... , Splenic Sequestration in Sickle Cell Anemia, Splenic Sequestration. ... However, less severe forms of Sickle Cell Disease can occur in adulthood ... Sickle Cell Anemia with Splenic Sequestration. Aka: Sickle Cell Anemia with Splenic Sequestration, Splenic Sequestration in ... Splenic infarction typically occurs by Puberty in patients with Hemoglobin SS. * ...
For this reason there is much need for more study of splenic diseases, in the hope that we can arrive at a better understanding ... Surgical Aspects of Splenic Disease. AMA Arch Surg. 1955;71(1):33-46. doi:10.1001/archsurg.1955.01270130035006 ... In the period 1936 to 1954 we have performed splenectomy on 137 patients with splenic disease. This excludes splenectomy for ... However, in numerous other diseases, such as Bantis disease, acquired hemolytic anemia, and secondary thrombocytopenic purpura ...
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A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists ... Diseases expand submenu for Diseases * Browse A-Z * Find Diseases By Category expand submenu for Find Diseases By Category * ... Find Diseases By Category expand submenu for Find Diseases By Category *Autoimmune / Autoinflammatory diseases ... contact gard Office of Rare Disease Research Facebook Page Office of Rare Disease Research on Twitter ...
title = "Concurrent Diseases and Conditions in Dogs with Splenic Vein Thrombosis",. abstract = "Background: Splenic venous ... Concurrent Diseases and Conditions in Dogs with Splenic Vein Thrombosis. Together they form a unique fingerprint. * Splenic ... Concurrent Diseases and Conditions in Dogs with Splenic Vein Thrombosis. M. P. Laurenson, Katrina Hopper, M. A. Herrera, Eric G ... Concurrent Diseases and Conditions in Dogs with Splenic Vein Thrombosis. / Laurenson, M. P.; Hopper, Katrina; Herrera, M. A.; ...
Ahmad, Q. A., & Ahmed, M. S. (1). Splenic Hydatid, A Rare Presentation of Hydatid Disease. Annals of King Edward Medical ... History and clinical examination gave the clinical suspicion of splenic hydatid. Ultrasonography and CT scan of the abdomen ... In conclusion, although rare but a high degree of suspicion should be there when splenic cyst is encountered. ...
Other etiological non-cardiovascular disorders are hematological diseases, thrombotic diseases, collagen tissue diseases, ... Pneumococcal Sepsis as a Cause of Massive Splenic Infarction in Patient with Unknown Celiac Disease Alessandro Graziani1*, ... Splenic Infarction (SI) is a rare event that occurs when the Splenic Artery (SA) or its branches become occluded by embolus or ... However malignant hematological disorders and autoimmune diseases are the predominant causes of splenic thrombosis [2]. Massive ...
  • What is splenic sequestration? (healthlinkbc.ca)
  • Splenic sequestration is a problem with the spleen that can happen in people who have sickle cell disease . (healthlinkbc.ca)
  • Splenic sequestration happens when a lot of sickled red blood cells become trapped in the spleen. (healthlinkbc.ca)
  • If splenic sequestration happens suddenly, it can be a life-threatening emergency. (healthlinkbc.ca)
  • This is called a splenic sequestration (SPLEN ik seh ques TRAY shun) crisis, or simply "spleen crisis. (nationwidechildrens.org)
  • These images are a random sampling from a Bing search on the term "Sickle Cell Anemia with Splenic Sequestration. (fpnotebook.com)
  • Of a cohort of 308 children with homozygous sickle cell disease diagnosed at birth, 89 experienced 132 clinically significant attacks of acute splenic sequestration (ASS) over a 10-year period. (ox.ac.uk)
  • A diagnosis of acute splenic sequestration crisis complicated by acute chest syndrome was crystallized, and red blood cell exchange transfusion was performed. (elsevier.com)
  • Further research is necessary to fully elucidate the pathophysiology behind acute splenic sequestration crisis, and the role of splenectomy to treat hemoglobin SC disease patients should be better defined. (elsevier.com)
  • The enhanced splenic sequestration of microspheres was accompanied by a decrease in the liver uptake. (portlandpress.com)
  • In early life, patients with sickle cell disease (SCD) can have acute, life-threatening emergencies related to splenic hypofunction (overwhelming bacterial sepsis), as well as anemic crises from acute splenic sequestration because of sudden pooling of blood in the spleen. (springer.com)
  • Dickerhoff R (2002) Splenic sequestration in patients with sickle cell disease. (springer.com)
  • Benjamin JT, McMillan CW, Komp DM (1979) Fatal splenic sequestration crisis. (springer.com)
  • Walterspiel JN, Rutledge JC, Bartlett BL (1984) Fatal acute splenic sequestration at 4 months of age. (springer.com)
  • Emond AM, Collis R, Darvill D et al (1985) Acute splenic sequestration in homozygous sickle cell disease: natural history and management. (springer.com)
  • Grover R, Wethers DL (1990) Management of acute splenic sequestration crisis in sickle cell disease. (springer.com)
  • Vick LR, Gosche JR, Islam S.Partial splenectomy prevents splenic sequestration crises in sickle cell disease. (yahoo.com)
  • Multiple Splenic Artery Aneurysms: A Rare Cause of Extrahepatic Portal Hypertension and Massive Splenomegaly. (ebscohost.com)
  • Splenomegaly with massive splenic infarction. (isciii.es)
  • Unlike sickle cell disease, which causes splenic infarction, Gaucher disease causes splenomegaly. (medscape.com)
  • Since the association between inflammatory bowel disease and functional hyposplenism is well described, our aim was to verify whether IgM memory B cells mirror the reduced splenic function in Crohn's disease and ulcerative colitis patients. (nih.gov)
  • Graziani A, Cappa FM, Fiorini E, Casalini P, Albertini F (2019) Pneumococcal Sepsis as a Cause of Massive Splenic Infarction in Patient with Unknown Celiac Disease. (clinmedjournals.org)
  • Splenic Infarction (SI) is a rare event that occurs when the Splenic Artery (SA) or its branches become occluded by embolus or by in situ thrombosis [ 1 ]. (clinmedjournals.org)
  • Massive Splenic Infarction (MSI) results from compromised blood flow to more than half of the spleen [ 3 ]. (clinmedjournals.org)
  • This test revealed a complete loss of splenic perfusion which suggested a massive infarction (Figure 1) confirmed also by abdominal CT with contrast material (Figure 2). (clinmedjournals.org)
  • An AngioCT was performed, revealing a large splenic infarction. (structuralheartdisease.org)
  • Teixeirense PT, de Toledo JFB, Gubolino LA, Bragalha AA, Pereira CA. Very Late Thrombosis of an Atrial Septal Defect Occluder Device Causing a Massive Splenic Infarction. (structuralheartdisease.org)
  • Key words: Massive splenic infarction. (isciii.es)
  • She was consequently diagnosed with haemoglobinopathy S and C, with haemolytic crises and massive splenic infarction in the context of an acute pyelonephritis. (isciii.es)
  • Two weeks later the patient was readmitted for a pain in the left hypochondrium and a temperature of 38 o C. Abdominal ultrasound revealed massive splenic infarction with probable superinfection. (isciii.es)
  • Emergency surgery was decided upon for superinfected massive splenic infarction, and a large-sized spleen was found adhering to the left liver lobe, stomach, pancreatic body and tail and abdominal wall, with old dark haematic content. (isciii.es)
  • The hypoxia caused when climbing to altitudes above 2,500 m may trigger vaso-occlusive processes and give rise to infarction, the most common of which is splenic (2,4). (isciii.es)
  • Ultrasonography and computed axial tomography diagnose splenic infarction, and electrophoresis of the red cell haemolysis enables the haemoglobinopathy to be typified. (isciii.es)
  • Initial treatment for splenic infarction must be conservative, aimed at correcting the precipitating factors and achieving an adequate oxygenation and hydration. (isciii.es)
  • Gaucher disease also expands the marrow cavity and causes bone marrow infarction. (medscape.com)
  • Sickle cell disease can produce an acute illness related to infarction of the lung tissue. (rch.org.au)
  • The imaging characteristics of splenic hydatid cysts are calcification of the cyst wall, the presence of daughter cysts and membrane detachment. (diagnosticimaging.com)
  • Anyway, some differentials diagnosis as epidermoid cysts, pseudocysts, splenic abscesses, hematomas and cystic neoplasms of the spleen should be considered2. (diagnosticimaging.com)
  • Cysts of the spleen are the most common benign focal splenic masses. (appliedradiology.com)
  • Pseudocysts are much more common, representing 80% of all splenic cysts. (appliedradiology.com)
  • Management of Non-Parasitic Splenic Cysts: Does Size Really Matter? (ebscohost.com)
  • Background: Splenic cysts are relatively rare clinical entities and are often diagnosed incidentally upon imaging conducted for a variety of clinical complaints. (ebscohost.com)
  • Nowadays, MRI permits the characterization of the most common splenic lesions, such as cysts, small hemangiomas, and hamartomas, and improvement in the detection of malignant diseases such as lymphoma and metastases [ 1 ]. (hindawi.com)
  • Computed tomography, magnetic resonance imaging, and 18 F-fluorodeoxyglucose positron emission tomography-computed tomography are useful to evaluate whether splenic metastasis of ovarian cancer is solitary, and laparoscopic splenectomy is safe and feasible for a solitary splenic metastasis. (biomedcentral.com)
  • Paluska et al (1) found incidental splenic lesions in 1% of patients in an emergency room population undergoing computed tomography (CT) scans for abdominal pain or trauma. (thefreelibrary.com)
  • Coronal view of unenhanced abdominal computed tomography demonstrating splenic enlargement with endocapsular hematoma and intraperitoneal hemorrhage (arrows). (cdc.gov)
  • Computed tomography of abdomen revealed multiple aneurysms in the distal half of the splenic artery. (ebscohost.com)
  • To better characterize the splenic nodules, chest, abdomen, and pelvis computed tomography (CT) scans ( Fig 2 ) and an abdominopelvic MRI scan ( Fig 3 ) were obtained. (aappublications.org)
  • Splenic infarcts fortunately are rare events, caused by occlusion of the splenic artery or one of its branches, which results in tissue necrosis. (teachmesurgery.com)
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Splenic infarcts. (cdc.gov)
  • Concurrent splenic infarcts were identified in 33% of dogs, and concurrent portal vein thrombi were found in 18% of dogs.Conclusions: SVT is a sonographic finding of clinical importance, and dogs with SVT can have 1 or more coexisting diseases. (elsevier.com)
  • 9 Splenic infarcts may be infected either by the emboli that caused them (eg, from endocarditis) or by secondary blood-born infection of a pre-existent defect ( Figure 2 ). (appliedradiology.com)
  • A splenic hydatid cyst should be treated surgically due to the risk of rupture. (diagnosticimaging.com)
  • Splenosis is defined as an autotransplantation of the splenic tissue after splenic rupture or splenectomy , and occurs most frequently in the peritoneal cavity . (bvsalud.org)
  • Splenic artery aneurysm rupture. (ebscohost.com)
  • Splenic artery aneurysm rupture is a rare but a serious complication especially when it occurs in pregnancy. (ebscohost.com)
  • Following is a case report of splenic artery aneurysm rupture in a primigravida woman who presented with a life threatening haemorrhage. (ebscohost.com)
  • The hazard of rupture of asymptomatic splenic artery aneurysms in pregnancy is well known. (ebscohost.com)
  • Pregnancy is a risk factor for splenic artery aneurysms rupture with high maternal mortality and fetal loss. (ebscohost.com)
  • Rupture of a splenic artery aneurysm is rare complication of pregnancy that is associated with a significant maternal and fetal mortality. (ebscohost.com)
  • Postpartum rupture of a splenic artery aneurysm: A case report and review of the literature. (ebscohost.com)
  • Few young patients with mononucleosis require medical imaging, although patients may present with symptoms and complications of splenic rupture after suffering trauma to their fragile, enlarged spleen (Figure 1) . (appliedradiology.com)
  • Laparoscopic splenectomy was performed as tertiary cytoreduction with a diagnosis of a solitary splenic metastasis. (biomedcentral.com)
  • In this article, the authors propose an algorithm based on clinical factors for narrowing the differential diagnosis of an incidental splenic mass. (thefreelibrary.com)
  • The differential diagnosis of focal splenic lesions can be divided into several categories. (thefreelibrary.com)
  • Hemoglobin electrophoresis confirmed a diagnosis of hemoglobin SC disease. (elsevier.com)
  • In addition, this report reviews the current literature on the clinical significance and presentation, morphologic and immunohistochemical findings, prognosis, differential diagnosis, pathogenesis and therapy of the splenic IPT. (biomedsearch.com)
  • therefore, it is important to be familiar to the major MRI characteristics of disease processes involving the spleen, in order to interpret the findings correctly, reaching whenever possible the appropriate diagnosis. (hindawi.com)
  • The diagnosis of HbSC disease is made with Hb electrophoresis. (medscape.com)
  • Predictive models of disease burden at diagnosis in persons with adult-onset ulcerative colitis using health administrative data. (medscape.com)
  • Wiesner W, Steinbrich W. [Imaging diagnosis of inflammatory bowel disease]. (medscape.com)
  • The American College of Rheumatology has developed classification criteria for lupus, used as a aid in the diagnosis of this complex multi-organ system disease, but primarily intended for use in studies. (rheumatology.org)
  • In one patient, multiple splenic artery aneurysms. (ebscohost.com)
  • Abdominal ultrasound showing ascites and multiple splenic nodular masses (top of the image). (aappublications.org)
  • Abdominal CT scan showing a heterogeneous area of low-attenuation above normal splenic tissue (right side of image). (aappublications.org)
  • T2-weighted abdominal MRI showing nodules with a heterogeneous and hyperintense signal compared with the normal splenic tissue (right side of image). (aappublications.org)
  • One candidate mechanism may involve downregulation of the cytokine BAFF (also known as TNFSF13B), an essential survival factor for splenic B cells that is required for normal splenic B cell numbers 12 . (nature.com)
  • However malignant hematological disorders and autoimmune diseases are the predominant causes of splenic thrombosis [ 2 ]. (clinmedjournals.org)
  • Dr. Stewart offers a minimally invasive surgical solution to a wide range of problems, including obesity, acid reflux, benign and malignant colon disease, gall bladder disease, and complex stomach and esophageal disease. (swedish.org)
  • In fact, approximately 30% of patients with splenic enlargement do not have malignant involvement. (medscape.com)
  • The spleen may be involved in several pathologic conditions like congenital diseases, trauma, inflammation, vascular disorders and hematologic disorders, benign and malignant tumors, and other disease processes that focally or diffusely affect the spleen. (hindawi.com)
  • While some splenic tumors are benign, approximately two-thirds are highly malignant and carry a poor prognosis. (akcchf.org)
  • Hemangiosarcoma (HSA) accounts for the majority of canine malignant splenic tumors and occurs in many large dog breeds, including mixed breeds. (akcchf.org)
  • Pancreaticoduodenectomies are increasingly used to treat a variety of malignant and benign diseases of the pancreas. (encyclopedia.com)
  • This study aimed to evaluate certain VBP in samples from dogs with splenic lesions. (biomedcentral.com)
  • Sixty EDTA-blood samples from dogs without evidence of splenic lesions were included as a control group. (biomedcentral.com)
  • A diagnostic approach to splenic lesions. (thefreelibrary.com)
  • Most splenic lesions are detected incidentally, posing a challenge for both interpreting and referring physicians in determining the need for and type of further evaluation. (thefreelibrary.com)
  • Sarcoidosis is a multisystem inflammatory process that can present with splenic lesions in addition to other organ involvement as the lungs and mediastinum. (thefreelibrary.com)
  • As previously noted, most splenic lesions are found incidentally. (thefreelibrary.com)
  • Despite advances in imaging and pathologic definition, the etiology and medical relevance of splenic lesions in dogs are often ambiguous. (akcchf.org)
  • Cat scratch disease produces focal hepatosplenic lesions less than 2 cm in size (Figure 3). (appliedradiology.com)
  • Initial lesions may evolve to echogenic, presumably calcified splenic lesions (Figure 3). (appliedradiology.com)
  • Focuses on the disease splenic artery aneurysm. (ebscohost.com)
  • A Case of Ruptured Splenic Artery Aneurysm in Pregnancy. (ebscohost.com)
  • Splenic artery aneurysm is the most common visceral artery aneurysm (Lang et al, 2002). (ebscohost.com)
  • Idiopathic portal hypertension associated with intrahepatic portal aneurysm and splenic artery aneurysm. (nii.ac.jp)
  • I had an X-ray for scatia pain and found what was said to be a calcified splenic aneurysm s. (medhelp.org)
  • Embolization of giant aneurysm and pseudoaneurysm of the splenic artery. (ebscohost.com)
  • Presents a letter to the editor related to embolization of giant aneurysm and pseudoaneurysm of the splenic artery. (ebscohost.com)
  • Al-Salem AH, Naserullah Z, Qaisaruddin S et al (1999) Splenic complications of the sickling syndromes and the role of splenectomy. (springer.com)
  • To the editor: Cunningham and Zone (1) have recently reported a significant but unexplained association between clinical thyroid disease, thyroid autoantibodies, and dermatitis herpetiformis. (annals.org)
  • Splenic abscesses occur in a variety of clinical scenarios. (medscape.com)
  • There is 1 clinical trial for splenic diffuse red pulp small B-cell lymphoma, of which 1 is open and 0 are completed or closed. (mycancergenome.org)
  • BRAF is the most frequent gene inclusion criterion for splenic diffuse red pulp small B-cell lymphoma clinical trials [ 3 ]. (mycancergenome.org)
  • Vemurafenib is the most common intervention in splenic diffuse red pulp small B-cell lymphoma clinical trials. (mycancergenome.org)
  • History and clinical examination gave the clinical suspicion of splenic hydatid. (annalskemu.org)
  • Clinical factors must be taken into account when evaluating a splenic lesion, most importantly pain attributable to the spleen, signs and symptoms of infection, immune status, history of known malignancy, associated findings on imaging of the chest, abdomen or pelvis and a history of abdominal trauma, either recent or remote. (thefreelibrary.com)
  • Dr. Ong's clinical practice focuses on the treatment of all gastrointestinal cancers with particular interest in treatment options for pancreatico-biliary cancers as well as regional and metastatic disease. (swedish.org)
  • Olujohungbe A, Howard J. The clinical care of adult patients with sickle cell disease. (medscape.com)
  • Seventy-seven EDTA-blood and 64 splenic tissue samples were collected from 78 dogs with splenic disease in a Mediterranean area. (biomedcentral.com)
  • Published studies suggest that preexisting splenic tissue injury and bacteremia are required to form a basis for an abscess. (medscape.com)
  • Immunohistochemical staining demonstrated Rickettsia in endothelial cells and macrophages in the spleen and skin ( Figure , panels D - F ). Blood culture, skin biopsy specimens, and splenic tissue cultures were subsequently R. conorii positive. (cdc.gov)
  • Bartonella species exist worldwide and are transmitted by blood-sucking arthropods (e.g. ticks, fleas) and their presence in splenic tissue could potentially be explained by the fact that the spleen is primarily responsible for removal of blood-borne parasites from the systemic circulation. (akcchf.org)
  • We of infectious respiratory and neurologic disease in com- assessed the role that tissue tropism and shedding charac- mercially farmed pigs, presumably after virus spillover teristics of NiV-Malaysia and NiV-Bangladesh might play from Malaysian fl ying foxes ( 2 ). (cdc.gov)
  • This makes children with sickle cell disease more likely to get infections that can make them very sick. (nationwidechildrens.org)
  • Some children with sickle cell disease normally have a big spleen. (nationwidechildrens.org)
  • The prevalence of functional asplenia in Omani children with sickle cell disease (SCD) has not been previously defined. (elsevier.com)
  • Shatat IF, Jakson SM, Blue AE, Johnson MA, Orak JK, Kalpatthi R. Masked hypertension is prevalent in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. (medscape.com)
  • All children with sickle cell disease are managed with the assistance of the Royal Children's Hospital Victoria. (rch.org.au)
  • Splenectomy in young children with sickle cell disease carries a low risk of postsplenectomy sepsis with appropriate vaccination and prophylactic antibiotics. (yahoo.com)
  • Evaluation of partial and total splenectomy in children with sickle cell disease using an Internet-based registry. (yahoo.com)
  • Both children were running a mild course of the disease with infrequent admissions due to acute painful crises. (thefreelibrary.com)
  • However, in patients with a known malignancy or symptoms attributable to possible splenic pathology, the incidentally discovered splenic lesion may be more significant. (thefreelibrary.com)
  • Depletion of immunoglobulin M memory B cells is associated with splenic hypofunction in inflammatory bowel disease. (nih.gov)
  • Increase in the percentage of 'pitted erythrocytes' above the control range indicated splenic hypofunction. (clinsci.org)
  • 5. Counting of 'pitted erythrocytes' is a simple and sensitive method of assessing splenic hypofunction in treated coeliac disease. (clinsci.org)
  • 6. The incidence of splenic hypofunction in coeliac patients may be related to the duration of untreated disease. (clinsci.org)
  • The size and location of a splenic abscess determines its relations to the surrounding organs and the possible routes for extension or fistulization. (medscape.com)
  • This patient has splenic abscess due to pneumococcal bacteremia. (medscape.com)
  • Infective endocarditis, a condition associated with systemic embolization in 22-50% of cases, has a 10-20% incidence of associated splenic abscess. (medscape.com)
  • Primary abscess of the omentum is an infrequecnt disease entity. (dict.cn)
  • Splenic abscess is a rare and potentially life-threatening disease. (dict.cn)
  • Is Splenic Flexure Mobilization Necessary in Laparoscopic An. (lww.com)
  • Abscesses originating from the lower pole can involve the splenic flexure and communicate with the colonic lumen. (medscape.com)
  • 1. Erythrocytes with membrane abnormalities seen on interference contrast microscopy ('pitted erythrocytes') were counted in venous blood samples from patients with treated coeliac disease and dermatitis herpetiformis, and from control subjects and patients who had had an elective splenectomy. (clinsci.org)
  • Background: Splenic venous thrombosis (SVT) is usually considered an incidental finding on abdominal ultrasound examination but can indicate the presence of underlying disease. (elsevier.com)
  • In the portal venous phase, splenic enhancement becomes homogeneous. (thefreelibrary.com)
  • The splenic hilum is found within this concavity and acts as an entry and exit route for the arterial, venous, and lymphatic vessels and nerves. (hindawi.com)
  • Accuracy of abdominal ultrasound and MRI for detection of Crohn disease and ulcerative colitis in children. (medscape.com)
  • We report the case of a female patient diagnosed with sickle cell disease following a massive splenic infarct. (isciii.es)
  • p. 89): 'I have found it quickly and surely helpful in painful spleen diseases ─ affections painful and beyond any doubt in and of the spleen. (homeoint.org)
  • Due to the limited and nonspecific symptoms, splenic hydatid disease has a long latency period. (diagnosticimaging.com)
  • Monarch's tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. (cdc.gov)
  • Symptoms of HbSC disease are similar to SCD but less frequent and less severe. (medscape.com)
  • 3) If a splenic lesion with benign imaging characteristics (either a cyst or homogeneous, low-attenuation with no enhancement and smooth margins) is detected in an asymptomatic patient, no follow-up imaging is necessary. (thefreelibrary.com)
  • Spleen compromise in hydatid disease is uncommon, its frequency is estimated between 0.9 percent and 8 percent of cases, with most developed from systemic or intraperitoneal dissemination product of a ruptured liver cyst1. (diagnosticimaging.com)
  • What is the sensitivity of CT scans for detecting liver and splenic involvement in thoracic non-Hodgkin lymphoma (NHL)? (medscape.com)
  • In NHL, liver and splenic involvement is seen in 15% and 22% of patients, respectively. (medscape.com)
  • Sensitivity rates for CT are 15-37% for infiltrative splenic disease and 19-33% for infiltrative liver disease. (medscape.com)
  • Methods: Tuftsin activity and splenic function were assessed in 31 patients with liver cirrhosis and 31 healthy subjects. (bmj.com)
  • Abdominal CT showed a largely fatty splenic mass with enhancing septations, and scattered calcifications, and a small density in the liver. (biomedsearch.com)
  • The dog's previous history included occasional generalized seizures of unknown etiology beginning 4 years prior to presentation, suspected inflammatory bowel disease, proteinuria [urine protein:creatinine ratio (UPC) 1.25], and decreased hepatic function. (frontiersin.org)
  • Small solitary or multiple abscesses tend to remain contained by the splenic capsule. (medscape.com)
  • Splenic abscesses have diverse etiologies. (medscape.com)
  • Large liquefied splenic abscesses can often be drained percutaneously, either with curative intent or as a temporizing measure prior to surgical treatment. (appliedradiology.com)
  • In rare cases cat scratch disease can present with larger, pyogenic abscesses. (appliedradiology.com)
  • Splenic Diffuse Red Pulp Small B-Cell Lymphoma, also known as splenic diffuse red pulp lymphoma , is related to b-cell lymphoma and hairy cell leukemia . (malacards.org)
  • An important gene associated with Splenic Diffuse Red Pulp Small B-Cell Lymphoma is BCOR (BCL6 Corepressor), and among its related pathways/superpathways are GPCR Pathway and PI3K-Akt signaling pathway . (malacards.org)
  • The most common neoplastic disease was lymphoma, and the most common immune-mediated disease was immune-mediated hemolytic anemia. (elsevier.com)
  • Of the trial that contains splenic diffuse red pulp small B-cell lymphoma as an inclusion criterion, 1 is phase 2 (1 open). (mycancergenome.org)
  • In this study, we genetically dissect the contributions of individual MHC class I family members and the pathological processes under their control in the systemic lupus erythematosus-like disease of BXSB. (jimmunol.org)
  • However, dysregulation of the response can lead to the development of a spectrum of immunological disorders including the prototypic autoantibody-dependent disease, systemic lupus erythematosus (SLE), as well as B cell lymphomas of germinal center (GC) and post-GC origin. (jimmunol.org)
  • usually myocardial irritation or damage due to primary cardiac or systemic disease. (vetstream.com)
  • Infection was significantly associated to the presence of splenic disease ( P = 0.013). (biomedcentral.com)
  • VBP infection could be involved in the pathogenesis of splenic disease. (biomedcentral.com)
  • We hypothesise that after initial control of invasive infection by the spleen, bacteraemia associated with pneumonia arises from a sub-set of splenic macrophages that are permissive for bacterial replication. (microbiologyresearch.org)
  • Infection of mice with cytopathic foot-and-mouth disease virus (FMDV) induces a rapid and specific thymus-independent (TI) neutralizing antibody response that promptly clears the virus. (conicet.gov.ar)
  • Onwubalili JK (1983) Sickle cell disease and infection. (springer.com)
  • The investigators will perform a comprehensive examination of the potential association between Bartonella infection and HSA by comparing the prevalence of Bartonella DNA in tumor and blood samples from both splenic and cardiac HSA cases, and also within and between distant geographical locations in the US. (akcchf.org)
  • Bartonella species cause the bacterial granulomatous infection known as cat scratch disease. (appliedradiology.com)
  • Infections with tick-borne rickettsiae can cause diseases well known in humans but still not so well characterized in dogs. (biomedcentral.com)
  • Tick-borne diseases are of substantial concern worldwide for animals as well as humans. (biomedcentral.com)
  • The authors do not appear to have considered the possible role of associated splenic atrophy, which occurs in up to one third of patients with dermatitis herpetiformis (2), in the development of these autoimmune findings. (annals.org)
  • Occult celiac disease presenting as splenic vein thrombosis. (bvsalud.org)
  • If the disease affects the splenic artery or vein, the spleen is also removed. (encyclopedia.com)
  • Our aims were to determine whether tuftsin activity is deficient in cirrhosis and if so, whether this deficiency is related to splenic function, contributes to altered neutrophil granulocyte function, or influences the occurrence of bacterial infections and patient survival. (bmj.com)
  • Such an abnormality appears to be related to impaired splenic function and severity of cirrhosis, and probably favours the occurrence of bacterial infections. (bmj.com)
  • To associate these infectious foci to invasive pneumococcal disease during pneumonia, we analysed spleens in a baboon pneumonia model, and detected pneumococcal clusters in splenic macrophages. (microbiologyresearch.org)
  • In this paper we describe a case of a previously healthy patient who presented with pneumococcal sepsis who upon investigation revealed an unknown celiac disease and a MSI. (clinmedjournals.org)
  • Because the residing area was an endemic hydatid disease zone, a primary spleen hydatid cyst was suspected. (diagnosticimaging.com)
  • The authors postulate an immunogenetic predisposition to the development of these abnormalities and mention the increased prevalence of HLA-B8 and HLA-DRw3 in patients with dermatitis herpetiformis and those with autoimmune thyroid disease. (annals.org)
  • Finally, autoimmune disease, sarcoidosis, and sarcoid-like reaction are examples of inflammatory disease which may have splenic manifestations. (appliedradiology.com)
  • Peripheral blood samples were obtained from 32 Crohn's disease and 29 ulcerative colitis patients, 33 healthy controls, and 27 splenectomized patients. (nih.gov)
  • Perendoscopic intestinal biopsies were also collected from 15 of 32 Crohn's disease patients, 14 of 29 ulcerative colitis patients and 13 of 33 control subjects. (nih.gov)
  • In inflammatory bowel disease patients circulating IgM memory B cells were significantly lower than in control subjects. (nih.gov)
  • We observed a significant inverse correlation between the frequency of circulating IgM memory B cell and the pitted red cell values in inflammatory bowel disease patients with hyposplenism. (nih.gov)
  • Our findings show that peripheral IgM memory B cells are reduced in inflammatory bowel disease patients and this defect seems to be related to the impairment of splenic function. (nih.gov)
  • Solitary splenic metastasis of epithelial ovarian cancer is rare in patients with post-treatment ovarian cancer with long disease-free intervals. (biomedcentral.com)
  • Therefore, splenic metastasis of epithelial ovarian cancer is usually found in patients at the terminal stage. (biomedcentral.com)
  • Ashley Magee, DVM, DACVS, discusses the spleen and emergency management of patients with splenic diseases. (atdove.org)
  • In the period 1936 to 1954 we have performed splenectomy on 137 patients with splenic disease. (jamanetwork.com)
  • In this study, the authors aim to compare the natural history of splenic dysfunction in their patients to other reports. (elsevier.com)
  • The splenic function was studied in 72 Omani patients with sickle cell disease (50 homozygous for hemoglobin S (Hb S-S), 11 double heterozygotes for HbS and β 0 -thalassemia (HbS-β 0 -thal), 5 HbS-β + -thal, 5 patients with hemoglobin S-D disease, and 1 child with hemoglobin S oman trait) aged 4.8-16 years, using 99m Tc-labeled tin colloid scintigraphy. (elsevier.com)
  • The previously described permanent, complete and nearly universal "autosplenectomy" emerging by late childhood or early adulthood is now challenged by recent findings of reversibility of splenic dysfunction by the antisickling drug hydroxyurea or by successful allogeneic stem cell transplantation, even in older patients. (springer.com)
  • Patients who did not progress or have unacceptable toxicity in the Vem1 Phase were retreated with vemurafenib (Vem 2 Phase) at the last dose level identified at the end of the Vem1 Phase until disease progression or unacceptable toxicity. (clinicaltrials.gov)
  • Patients who are considered suitable for surgery usually have small tumors in the head of the pancreas (close to the duodenum, or first part of the small intestine), have jaundice as their initial symptom, and have no evidence of metastatic disease (spread of cancer to other sites). (encyclopedia.com)
  • In most patients with the alcohol-induced disease, the pancreas is widely involved, therefore, surgical correction is almost impossible. (encyclopedia.com)
  • The clinically important diseases involved, observed in patients in the United States, are HbSC and Hb-beta thalassemia. (medscape.com)
  • Pathologists have recognized that spleen weight does not follow a bell-shaped curve, even in patients with no disease affecting the spleen. (appliedradiology.com)
  • Patients are functionally asplenic and thus at greater risk for invasive disease particularly by encapsulated organisms. (rch.org.au)
  • NiV-Malaysia emerged in 1998 during an outbreak disease in NiV-Bangladesh-infected patients ( 14 , 21 ). (cdc.gov)
  • 1) Between 30-67% of patients with sickle cell disease (SCD) get infected causing transient red cell aplasia (TRCA), otherwise called aplastic crisis. (thefreelibrary.com)
  • Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD), along with Crohn disease (CD). (medscape.com)
  • Carucci LR, Levine MS. Radiographic imaging of inflammatory bowel disease. (medscape.com)
  • We present a rare case of a solitary splenic metastasis of epithelial ovarian cancer, which occurred after a 5-year disease-free interval, and laparoscopic splenectomy as tertiary cytoreduction for the metastatic tumor. (biomedcentral.com)
  • Laparoscopic splenectomy for giant splenic cyst. (wakehealth.edu)
  • Splenic myoid angioendothelioma mimicking metastatic disease in an 8-y" by Adil A. Shah, Luca Dragos et al. (gwu.edu)
  • January 11, 1946, Birigüi, São Paulo) is a Brazilian physician and prominent medical scientist, who is active in the fields of hereditary diseases of the blood (hemoglobins, clotting, thrombosis), molecular basis of cancer and human population genetics. (wikipedia.org)
  • 2) CT imaging demonstrates heterogeneous splenic enhancement on arterial phase imaging, due to variation in blood flow through the sinuses and cords. (thefreelibrary.com)
  • Arterial Dysplasia and Splenic Artery Aneurysms. (ebscohost.com)
  • Arterial dysplasia is an important etiologic basis of splenic artery aneurysms in women of child-bearing age. (ebscohost.com)
  • Recently, we have shown that experimental murine sepsis is preceded by intracellular replication within splenic macrophages (Ercoli Nat Microbiol 2018), which shed into the bloodstream initiating invasive disease. (microbiologyresearch.org)
  • Possibility of statistical assessment of splenic involvement in Hodgkin's disease independently of splenectomy. (elsevier.com)
  • The spleen is a highly perfused organ involved in the immunological control and elimination of vector-borne pathogens (VBP), which could have a fundamental role in the pathogenesis of splenic disease. (biomedcentral.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • In abdominal imaging, signs of infectious and inflammatory disease may present solely in the spleen. (appliedradiology.com)
  • Splenic epidermoid cyst is a rare cystic disease of spleen. (ebscohost.com)
  • In the following days the patient was febrile and required a surgical and infectious disease consultation. (clinmedjournals.org)
  • Although there are experimental medical treatment options surgical excision remains the current recommended primary therapy for symptomatic disease. (ebscohost.com)
  • The histopathological study of the surgical specimen revealed a massively necrotic splenic parenchyma with large areas of abscessification. (isciii.es)
  • My surgical practice encompasses the management of the following diseases. (healthpoint.co.nz)
  • These results indicate that the predominant role of the MHC class I protein family in such immunological disorders is to protect from more aggressive diseases. (jimmunol.org)
  • Keymer [ 8 ] in 1983 was the first to describe the range of diseases affecting red squirrels in Britain but there were few comparable studies until 2010 when LaRose et al. (biomedcentral.com)
  • The purpose of the present study was, firstly, to investigate the causes of mortality and any associated pathological findings in red squirrels from geographically isolated populations in Britain, and secondly, to consider the factors that might influence the occurrence of disease in these populations. (biomedcentral.com)
  • The major reason is the low frequency of splenic abnormalities, the majority consisting of incidental findings. (hindawi.com)