Spinal cord neoplasms. Medical search

Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.

A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.

Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.

Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.

Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.

Introduction of therapeutic agents into the spinal region using a needle and syringe.

Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.

Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.

The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The spinal nerve plexuses and the spinal roots are also included.

Neurons which activate MUSCLE CELLS.

Repair of the damaged neuron function after SPINAL CORD INJURY or SPINAL CORD DISEASES.

The cavity within the SPINAL COLUMN through which the SPINAL CORD passes.

The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.

Procedure in which an anesthetic is injected directly into the spinal cord.

Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.

A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.

The flexible rope-like structure that connects a developing FETUS to the PLACENTA in mammals. The cord contains blood vessels which carry oxygen and nutrients from the mother to the fetus and waste products away from the fetus.

Neurons in the SPINAL CORD DORSAL HORN whose cell bodies and processes are confined entirely to the CENTRAL NERVOUS SYSTEM. They receive collateral or direct terminations of dorsal root fibers. They send their axons either directly to ANTERIOR HORN CELLS or to the WHITE MATTER ascending and descending longitudinal fibers.

A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Region of the back including the LUMBAR VERTEBRAE, SACRUM, and nearby structures.

A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.

Renewal or physiological repair of damaged nerve tissue.

Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.

Narrowing of the spinal canal.

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.

Application of electric current to the spine for treatment of a variety of conditions involving innervation from the spinal cord.

Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.

Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)

Injuries involving the vertebral column.

MOTOR NEURONS in the anterior (ventral) horn of the SPINAL CORD which project to SKELETAL MUSCLES.

Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Any operation on the spinal cord. (Stedman, 26th ed)

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.

Neoplasms containing cyst-like formations or producing mucin or serum.

An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.

Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.

Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.

Elements of limited time intervals, contributing to particular results or situations.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

Use of electric potential or currents to elicit biological responses.

The spinal or vertebral column.

Space between the dura mater and the walls of the vertebral canal.

Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.

Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. This is often associated with SPINAL CORD DISEASES, but may also be caused by BRAIN DISEASES or PERIPHERAL NERVE DISEASES.

A rare epidural hematoma in the spinal epidural space, usually due to a vascular malformation (CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS) or TRAUMA. Spontaneous spinal epidural hematoma is a neurologic emergency due to a rapidly evolving compressive MYELOPATHY.

Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)

Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.

Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.

VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.

An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.

Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.

Common name for the only family (Petromyzontidae) of eellike fish in the order Petromyzontiformes. They are jawless but have a sucking mouth with horny teeth.

Tumors or cancer of the SKIN.

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)

The physical activity of a human or an animal as a behavioral phenomenon.

A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)

Most generally any NEURONS which are not motor or sensory. Interneurons may also refer to neurons whose AXONS remain within a particular brain region in contrast to projection neurons, which have axons projecting to other brain regions.

Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Recording of the changes in electric potential of muscle by means of surface or needle electrodes.

Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

Osteitis or caries of the vertebrae, usually occurring as a complication of tuberculosis of the lungs.

The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.

The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.

Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery.

Act of eliciting a response from a person or organism through physical contact.

The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.

Injuries resulting in hemorrhage, usually manifested in the skin.

The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.

Tumors or cancers of the KIDNEY.

The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.

Deformities of the SPINE characterized by abnormal bending or flexure in the vertebral column. They may be bending forward (KYPHOSIS), backward (LORDOSIS), or sideway (SCOLIOSIS).

A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.

Either of a pair of tubular structures formed by DUCTUS DEFERENS; ARTERIES; VEINS; LYMPHATIC VESSELS; and nerves. The spermatic cord extends from the deep inguinal ring through the INGUINAL CANAL to the TESTIS in the SCROTUM.

A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.

Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)

Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.

A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)

Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.

An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.

The lower part of the SPINAL CORD consisting of the lumbar, sacral, and coccygeal nerve roots.

A group of recessively inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)

Refers to animals in the period of time just after birth.

A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

An intermediate filament protein found only in glial cells or cells of glial origin. MW 51,000.

Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions.

Broken bones in the vertebral column.

Chairs mounted on wheels and designed to be propelled by the occupant.

Extraneural metastasizing ependymoma of the spinal cord. (1/586)

This paper reports a case of the rare entity of an extraneural metastasizing ependymoma of the spinal cord. The tumor which arose in the conus medullaris and in the cauda equina was first diagnosed in 1956 when a thoracolumbar myeloresection was performed. At autopsy, 40 years after the primary diagnosis, a massive local tumor recurrence with extraneural metastases in the lungs, the pleura, the liver, and the thoracal and abdominal lymph nodes were found. Immunohistochemical stains of the extraneural metastases showed a strong cytoplasmatic expression of glial fibrillary acidic protein (GFAP). Neither the primary tumor nor its metastases showed any of the conventional morphological criteria of malignancy. Reviewing the literature we discuss the possible mechanism of extraneural tumor spread and the incidence of metastases with regard to the tumor type. (+info)

Recurrent spinal epidural metastases: a prospective study with a complete follow up. (2/586)

OBJECTIVES: Prospective studies with a complete follow up in patients with spinal epidural metastases (SEM) are rare, so little is known of the incidence and relevance of recurrent spinal epidural metastases (RSEM). This prospective study was undertaken as a part of a previously started and extended prospective study to determine the occurrence and details of RSEM. METHODS: Patients with SEM of various primary malignancies were followed up until death. The diagnosis was confirmed after neurological examination by imaging studies visualising not only the clinically suspected level, but also as much of the spinal canal as possible. RESULTS: Recurrent spinal epidural metastases (RSEM) occurred in 21 of the 103 patients (20%) after a median interval of 7 months and, after treatment, a second recurrence occurred in 11 patients (11%), a third recurrence in two patients (2%), and a sixth recurrence in one patient (1%). RSEM developed about as often at the initial level (55%) as at a different level (45%), did not occur more often in patients with initially multiple SEM, but, not surprisingly, occurred much more often in patients with longer survival. About one half of the patients surviving 2 years, and nearly all patients surviving 3 years or longer developed RSEM. Ambulatory state could be preserved in most patients, even after their second recurrence. CONCLUSION: RSEM are common and even several episodes of RSEM in the same patient are not rare. Patients with SEM who survive long enough have a high risk of RSEM and prompt treatment of RSEM to maintain the ambulatory state of the patient is valuable. (+info)

Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Phase I Study Group of the Association for Medical Oncology of the German Cancer Society. (3/586)

Methotrexate-albumin conjugate (MTX-HSA) is a novel human albumin-based prodrug conjugate of methotrexate (MTX). A low MTX loading rate provided optimal tumor targeting and therapeutic efficacy during preclinical testing. The objectives of this first Phase I study of MTX-HSA were to determine dose-limiting toxicity (DLT) and maximum tolerated dose (MTD) in a weekly regimen. Seventeen cancer patients who were no longer amenable to standard treatment were enrolled and were evaluable for DLT. Up to eight injections were performed in weekly intervals. Dose escalation was as follows: 20, 40, 50, and then 60 mg/m2 MTX-HSA (based on the amount of MTX bound to albumin). Additional MTX-HSA courses were feasible in case of tumor response. DLT (mainly stomatitis, Common Toxicity Criteria grade 3) occurred, beginning at the 50 mg/m2 dose level after repeated administrations; in one case, thrombocytopenia was dose-limiting. Two events of DLT occurred at the 60 mg/m2 dose level within the first two administrations. Mild anemia, transaminitis, and one case of skin toxicity were found. No significant leukopenia, nausea, renal toxicity, or other toxicities were observed. MTX-HSA was well tolerated. Drug accumulation occurred on the weekly schedule. The half-life of the drug was estimated to be up to 3 weeks. Tumor responses were seen in three patients: (a) a partial response was seen in one patient with renal cell carcinoma (response duration, 30 months, ongoing); (b) a minor response was seen in one patient with pleural mesothelioma (response duration, 31 months, ongoing); and (c) a minor response was seen in one patient with renal cell carcinoma (response duration, 14 months until progression). Poststudy treatment was administered at 2-4-week intervals. No signs of toxicity or drug accumulation were seen. Altered pharmacological properties of MTX-HSA such as plasma half-life, tumor targeting, or intracellular metabolism might have contributed to these responses. The MTD for weekly administration was 4 x 50 mg/m2 MTX-HSA during short-term treatment. A regimen with MTX-HSA injections of 50 mg/m2 every 2 weeks was recommended for a further clinical Phase I study. (+info)

Diffusion tensor MR imaging and comparative histology of glioma engrafted in the rat spinal cord. (4/586)

MR imaging using contrast material derived from the diffusion of tissue water was tested for its ability to provide a nondestructive histologic analysis of tumor morphology. An apparent diffusion tensor MR image of a glioma engrafted within a rat spinal cord was generated in which fiber orientation in three dimensions was displayed in color. This imaging method clearly separated tumor from host white and gray matter and corresponded well with conventional histologic microscopy. (+info)

Second lung adenocarcinoma after combination chemotherapy in two patients with primary non-Hodgkin's lymphoma. (5/586)

We report a rare complication of a secondary malignant solid tumor in two patients with non-Hodgkin's malignant lymphoma who developed lung adenocarcinoma after treatments with combination chemotherapies. The first was a case of primary malignant lymphoma of the cervical spinal cord which had been previously treated with radiation to the spinal lesion and combination chemotherapies and entered complete remission. The patient was further treated for relapse with autologous bone marrow transplantation preconditioned with high-dose chemotherapy. Lung adenocarcinoma developed 5.5 years after the initial diagnosis. The second case of malignant lymphoma of lymph nodes did not respond to conventional combination chemotherapies and did not enter remission. Lung adenocarcinoma developed 1 year after the initial diagnosis. The two patients died of lung carcinoma. The clinical profiles of these cases are presented and the causal relationship of primary malignant neoplasms to the second malignant neoplasms is discussed. (+info)

Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. (6/586)

Ependymal tumors are heterogeneous with regard to morphology, localization, age at first clinical manifestation, and prognosis. Several molecular alterations have been reported in these tumors, including allelic losses on chromosomes 10, 17, and 22 and mutations in the NF2 gene. However, in contrast to astrocytic gliomas, no consistent molecular alterations have been associated with distinct types of ependymal tumors. To evaluate whether morphological subsets of ependymomas are characterized by specific genetic lesions, we analyzed a series of 62 ependymal tumors, including myxopapillary ependymomas, subependymomas, ependymomas, and anaplastic ependymomas, for allelic losses on chromosome arms 10q and 22q and mutations in the PTEN and NF2 genes. Allelic losses on 10q and 22q were detected in 5 of 56 and 12 of 54 tumors, respectively. Six ependymomas carried somatic NF2 mutations, whereas no mutations were detected in the PTEN gene. All six of the NF2 mutations occurred in ependymomas of WHO grade II and were exclusively observed in tumors with a spinal localization (P = 0.0063). These findings suggest that a considerable fraction of spinal ependymomas are associated with molecular events involving chromosome 22 and that mutations in the NF2 gene may be of primary importance for their genesis. Furthermore, our data suggest that the more favorable clinical course of spinal ependymomas may relate to a distinct pattern of genetic alterations different from that of intracerebral ependymomas. (+info)

Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2. (7/586)

A 15 year old male, who had earlier been operated for intraspinal intramedullary ependymoma, subsequently developed a right cerebello pontine (CP) angle mass. A diagnosis of right CP angle ependymoma was considered, in view of established histology of previously operated spinal lesion. Histopathological examination of the well defined extra-axial mass, which was attached with ninth cranial nerve, however revealed a schwannoma. A diagnosis of Neurofibromatosis-2 (NF2) is strongly suspected, because of well established fact, that the spinal ependymomas may have association with lower cranial nerve schwannomas in NF2. Cranial and spinal MRI screening for early diagnosis of associated, asymptomatic lesions, in suspected cases of NF2, particularly in children, is recommended. (+info)

Management of intramedullary spinal cord tumours: review of 68 patients. (8/586)

68 consecutive patients admitted with intramedullary spinal cord tumours and operated at Vellore during a six year period from January 1990 are discussed. 41 tumours were radically resected, 11 partially excised while 14 had only a biopsy. Radiation therapy was advised post operatively to those patients for whom a partial excision or biopsy was done. There was no postoperative mortality. Two patients developed wound infection and one developed postoperative hydrocephalus. Postoperative clinical assessment between four to eight weeks after surgery showed that 25 out of 68 patients improved, 29 remained unchanged, while 14 had worsening of deficits. Immediate post operative assessment, however, was less encouraging. Evaluation of these patients was done using a functional scoring system and Karnofsky rating. The follow up period ranged from 2 weeks to 64 months after discharge from hospital with a mean of 14.6 months. The indicators of radical excision were good tumour-cord interface, cranially located tumours, presence of syringomyelia and histology of ependymoma. Two patients had recurrence of tumour. (+info)

o spinal cord neoplasm Bougival Man preswyl. Q23728375, Berlin, Ivan Turgenev museum, Ivan Turgenev museum, Ivan Turgenev ...

https://cy.wikipedia.org/wiki/Ivan_Turgenev

There is one other sense of myeloid that means "pertaining to the spinal cord", but it is much less commonly used. Myeloid ... Myeloid neoplasms always concern bone marrow cell lineage and are related to hematopoietic cells. Myeloid tissue can also be ...

https://en.wikipedia.org/wiki/Myeloid_tissue

... s are neoplasms located in the spinal cord. Extradural tumors are more common than intradural neoplasms. Depending ... Spinal cord compression is commonly found in patients with metastatic malignancy. Back pain is a primary symptom of spinal cord ... often causing spinal cord compression, is key to maintaining quality of life in patients. The diagnosis of primary spinal cord ... inside the spinal cord Extramedullary- inside the dura, but outside the spinal cord Extradural tumors are mostly metastases ...

https://en.wikipedia.org/wiki/Spinal_tumor

Radiation on the Central Nervous System and Pituitary Gland of Macaque Monkeys A Study of 67 Brains and Spinal Cords and 77 ... Kent, S. P.; Pickering, J. E. (1958). "Neoplasms in monkeys (Macaca mulatta): spontaneous and irradiation induced". Cancer. 11 ... Radiation on the Central Nervous System and Pituitary Gland of Macaque Monkeys A Study of 67 Brains and Spinal Cords and 77 ... Pulmonary Ventilation and Oxygen Consumption Changes in Rhesus Monkeys Associated with Whole-Body Gamma-Irradiation Neoplasms ...

https://en.wikipedia.org/wiki/John_E._Pickering

... may refer to : Ruy Lopez chess openings ECO code Malignant neoplasm of spinal cord, cranial nerves and other parts of ...

https://en.wikipedia.org/wiki/C72

... spinal cord and motor neurons retina posterior pituitary Neural plate Neuroectodermal neoplasm Neuroepithelial cell Larsen's ...

https://en.wikipedia.org/wiki/Neuroectoderm

Spinal cord disorder Spinal cord injury Spinal cord neoplasm Spinal dysostosis type Anhalt Spinal muscular atrophy Spinal ... Spinal muscular atrophy with lower extremity predominance 1 Spinal muscular atrophy with lower extremity predominance 2 Spinal ... Spinal muscular atrophy with progressive myoclonic epilepsy Spinal muscular atrophy with respiratory distress type 1 Spinal ... Sphingolipidosis Spielmeyer-Vogt disease Spina bifida Spina bifida hypospadias Spinal and bulbar muscular atrophy Spinal ...

https://en.wikipedia.org/wiki/List_of_diseases_(S)

... is the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life ... Primary Spinal Cord Tumors Primary spinal cord tumors are uncommon and most are either astrocytomas or ependymomas. 1. Spinal ... Cord Metastasis The management of spinal cord metastasis depends on whether or not the metastasis is causing epidural spinal ... 2. Spinal Cord Tumor Presentations Pain is the first symptom in >90% of patients presenting with epidural metastasis and occurs ...

https://en.wikipedia.org/wiki/Neuro-oncology

"Tumefactive demyelination of the spinal cord: a case report". Spinal Cord. 53 (12): 877-880. doi:10.1038/sc.2015.52. PMID ... Symptoms also can mimic a neoplasm with symptoms such as headaches, aphasia, and/ or seizures.[13] There are some differences ... because in standard MS it is caused by demyelination or inflammation in the motor areas of the brain or the spinal cord. This ... and decrease in lesion size or detection of new lesions on serial imaging Tumefactive lesions can appear in the spinal cord, ...

https://en.wikipedia.org/wiki/Tumefactive_multiple_sclerosis

"Spinal Cord Tumors -- Nerve Sheath Tumors (Schwannomas and Neurofibromas)". Retrieved 2007-08-06. v t e. ... A nerve sheath tumor is a type of tumor of the nervous system (nervous system neoplasm) which is made up primarily of the ...

https://en.wikipedia.org/wiki/Nerve_sheath_tumor

... and the spinal cord. The tumor is usually gray, well-circumscribed, and takes on the form of the space it occupies. They ... The neoplasms currently referred to as meningiomas were referred to with a wide range of names in older medical literature, ... brain and spinal cord), but have various commonalities.[34][35] Charles Oberling then separated these into subtypes based on ... the membranous layers surrounding the brain and spinal cord.[1] Symptoms depend on the location and occur as a result of the ...

https://en.wikipedia.org/wiki/Meningioma

... the protective covering of the brain and spinal cord), the spine and/or its overlying tissues. Neuroplastic surgery has adapted ... Immediate Single-Stage Cranioplasty Following Calvarial Resection for Benign and Malignant Skull Neoplasms Using Customized ... Approaches to brain tumors Removal of skull and craniofacial tumors Complex Approaches to the spine and spinal cord Complex ...

https://en.wikipedia.org/wiki/Neuroplastic_surgery

... syndrome Ter Haar syndrome Teratocarcinosarcoma Teratoma Testes neoplasm Testotoxicosis Tetanus Tethered spinal cord disease ... mental retardation Thymic carcinoma Thymic epithelial tumor Thymic renal anal lung dysplasia Thymoma Thymus neoplasm ... syndrome Tolosa-Hunt syndrome Toluene antenatal infection Tomaculous neuropathy Tome-Brune-Fardeau syndrome Tongue neoplasm ... Trisomy 14 mosaicism Trisomy 2 mosaicism Trisomy 3 mosaicism Trisomy 6 Trisomy Trochlear dysplasia Trophoblastic Neoplasms ( ...

https://en.wikipedia.org/wiki/List_of_diseases_(T)

They may occur anywhere in the brain, or even in the spinal cord, but are most commonly found in the cerebral hemispheres. As ... because the borders of the neoplasm tend to send out tiny microscopic fibrillary tentacles that spread into the surrounding ...

https://en.wikipedia.org/wiki/Fibrillary_astrocytoma

Cerebrospinal fluid is tested for high amounts of the hormone β-hCG if the GTN has spread to the brain or spinal cord. Computed ...

https://en.wikipedia.org/wiki/Trophoblastic_neoplasm

... and cord edema. Poorly defined margins may be more suggestive of astrocytoma, while a central location in the spinal cord, ... It is nearly impossible to differentiate ganglioglioma from other more common intramedullary neoplasms based on imaging alone. ... Ganglioglioma of the Spinal Cord. J Clin Imaging Sci 2015;5:53". www.clinicalimagingscience.org. Retrieved 2015-10-01. Lang, F ... According to a series by Lang et al., reviewing several patients with resected spinal cord ganglioglioma, the 5- and 10-year ...

https://en.wikipedia.org/wiki/Ganglioglioma

... meninges Meningioma 192.2 Spinal cord 192.3 Spinal meninges 193 Malignant neoplasm of thyroid gland 194 Malignant neoplasm of ... 140 Malignant neoplasm of lip 141 Malignant neoplasm of tongue 142 Malignant neoplasm of major salivary glands 143 Malignant ... benign neoplasm of uterus 220 Benign neoplasm of ovary 221 Benign neoplasm of other female genital organs 222 Benign neoplasm ... neoplasm of oropharynx 147 Malignant neoplasm of nasopharynx 148 Malignant neoplasm of hypopharynx 149 Malignant neoplasm of ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_140–239:_neoplasms

... central cord syndrome MeSH C21.866.819.678 - spinal cord compression MeSH C21.866.831.600 - spinal fractures MeSH C21.866. ... neoplasms, radiation-induced MeSH C21.866.733.579 - osteoradionecrosis MeSH C21.866.733.720 - radiation injuries, experimental ... spinal injuries MeSH C21.866.117.500.500 - spinal fractures MeSH C21.866.120.126 - blast injuries MeSH C21.866.120.248 - ... spinal fractures MeSH C21.866.404.875 - tibial fractures MeSH C21.866.404.937 - ulna fractures MeSH C21.866.404.937.547 - ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C21)

"Consecutive Histological Changes in an Astroblastoma That Disseminated to the Spinal Cord after Repeated Intracranial ... often mistaking astroblastoma with glial neoplasms, high-grade astrocytes, and embryonal neoplasms. However, the "bubbly" ... even though it is entirely possible for lesions to proliferate toward the spinal cord. An enormous difficulty lies in ... the malignant spread of astroblastoma throughout the body may press against or paralyze the spinal cord, diminishing sensation ...

https://en.wikipedia.org/wiki/Astroblastoma

"Up-regulation of neural stem cell markers suggests the occurrence of dedifferentiation in regenerating spinal cord". ... Misago N, Narisawa Y (September 2006). "Cytokeratin 15 expression in neoplasms with sebaceous differentiation". Journal of ... tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord ... Grskovic B, Pollaschek C, Mueller MM, Stuhlmeier KM (June 2006). "Expression of hyaluronan synthase genes in umbilical cord ...

https://en.wikipedia.org/wiki/Stem_cell_marker

Spinal cord lesions. *Mechanical outlet obstruction *Internal intussusception. *Enterocele. *Dissipation of force vector * ... Neoplasms, benign or malignant. *Intussusception. *Volvulus. *Superior mesenteric artery syndrome, a compression of the ...

https://en.wikipedia.org/wiki/Intestinal_obstruction

Knudsen MA, Biering-Sørensen F. Spinal Cord. 2008 Mar;46(3):239-40. Epub 2007 Jul 3. ... Malignant neoplasm in burn scar: Marjolin's ulcer. Report of two cases and review of the literature]. Cir Cir. 2008 Jul-Aug;76( ... Urszula Ochenduszkiewicz,Rafał Matkowski Bartłomiej Szynglarewicz,Jan Kornafel "Marjolin's ulcer: malignant neoplasm arising in ...

https://it.wikipedia.org/wiki/Carcinoma_squamo-cellulare_di_Marjolin

MS symptoms develop as the cumulative result of multiple lesions in the brain and spinal cord. This is why symptoms can vary ... They look like intracranial neoplasms, and sometimes they get biopsied as suspected tumors. Proton MR spectroscopy can help in ... thalamus and spinal cord. Cortical lesions have been observed specially in people with SPMS but they also appear in RRMS and ... deep grey matter nuclei and the spinal cord". J Neurol Neurosurg Psychiatry. 80 (2): 182-7. doi:10.1136/jnnp.2008.148767. PMID ...

https://en.wikipedia.org/wiki/Lesional_demyelinations_of_the_central_nervous_system

The spinal cord is made up of bundles of these axons. Glial cells such as Schwann cells in the periphery or, within the cord ... Neoplasms will often show as differently colored masses (also referred to as processes) in CT or MRI results. ... Spinal cord and other tissuesEdit. The pons in the brainstem is a specific region that consists of myelinated axons much like ... The medulla oblongata is at the start of the spinal cord and is composed mainly of neuron tissue enveloped in oligodendrocytes ...

https://en.m.wikipedia.org/wiki/Brain_tumors

... including the cerebral hemispheres and the spinal cord. These tumors are usually slow growing and benign, corresponding to WHO ... The location could prohibit access to the neoplasm and lead to incomplete or no resection at all. Left unattended, these tumors ... The complaints may vary depending on the location and size of the neoplasm. The most common symptoms are associated with ... surgeons may decide to monitor the neoplasm's evolution and postpone surgical intervention for some time. However, total ...

https://en.wikipedia.org/wiki/Pilocytic_astrocytoma

In addition, lesions may mechanically interfere with the spinal cord or nerve roots, producing neurologic deficits. Pain and ... Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the bone. It has clinical and histologic manifestations ... Spinal lesions can cause painful scoliosis, although this is less common with osteoblastoma than with osteoid osteoma. ... The tumors usually involve the posterior elements, and 17% of spinal osteoblastomas are found in the sacrum. The long tubular ...

https://en.wikipedia.org/wiki/Osteoblastoma

... spinal cord neoplasms MeSH C10.228.854.765.342 - epidural neoplasms MeSH C10.228.854.770 - spinal cord injuries MeSH C10.228. ... spinal cord neoplasms MeSH C10.551.240.750.200 - epidural neoplasms MeSH C10.551.360.500 - optic nerve neoplasms MeSH C10.551. ... spinal cord vascular diseases MeSH C10.228.854.785.100 - anterior spinal artery syndrome MeSH C10.228.854.785.650 - spinal cord ... brain neoplasms MeSH C10.228.140.211.280 - cerebral ventricle neoplasms MeSH C10.228.140.211.280.300 - choroid plexus neoplasms ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C10)

Multiple sclerosis Spinal cord lesions Mechanical outlet obstruction Internal intussusception Enterocele Dissipation of force ... Neoplasms / cancer Diverticulitis / Diverticulosis Hernias Inflammatory bowel disease Colonic volvulus (sigmoid, caecal, ... sutures Pseudoobstruction Hernias containing bowel Crohn's disease causing adhesions or inflammatory strictures Neoplasms, ...

https://en.wikipedia.org/wiki/Bowel_obstruction

The spinocerebellum receives proprioception input from the dorsal columns of the spinal cord (including the spinocerebellar ... and neoplasms. In neonates, hypoxic injury to the cerebellum is fairly common, resulting in neuronal loss and gliosis. Symptoms ... each having distinct connections with the brain and spinal cord. These regions are the vestibulocerebellum, which is ... within the spinocerebellum and receives somatic sensory input from the head and proximal body parts via ascending spinal ...

https://en.wikipedia.org/wiki/Cerebellar_vermis

In the central nervous system, the three outer membranes (the meninges) that envelop the brain and spinal cord are composed of ... Connective tissue neoplasms including sarcomas such as hemangiopericytoma and malignant peripheral nerve sheath tumor in ...

https://en.m.wikipedia.org/wiki/Fibrous_connective_tissue

... or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly ... The continuation of the spinal cord within the skull, forming the lowest part of the brainstem and containing control centres ...

https://en.m.wikipedia.org/wiki/Glossary_of_biology

... for example when the tumor is wrapped around a vulnerable structure such as the spinal cord or a major organ or blood vessel.[ ... Hypopituitarism commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head ... When Dupuytren's disease is at the nodules and cords stage or fingers are at a minimal deformation stage of less than 10 ...

https://en.wikipedia.org/wiki/Radiation_therapy

Spinal cord compression can occur with metastases to the spine and can be treated with steroids, surgery, or radiation therapy ... "Male Genitals - Prostate Neoplasms". Pathology study images. University of Virginia School of Medicine. Archived from the ... Prostate cancer in the spine can also compress the spinal cord, causing tingling, leg weakness and urinary and fecal ...

https://fa.wikipedia.org/wiki/سرطان_پروستات?match=en

Cancer spreading into the Central nervous system (brain or spinal cord) has worse outcomes. ... "The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia". Blood. 127 (20): ... also known as a spinal tap) can determine whether the spinal column and brain have been invaded. Brain and spinal column ...

https://en.m.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

"Neoplasms and cancer" has been chosen to reflect the fact that not all tumours are benign. The word "cancer" has been included ...

https://kn.wikipedia.org/wiki/ಟೆಂಪ್ಲೇಟು:Central_nervous_system_navs

The spinal cord is made up of bundles of these axons. Glial cells such as Schwann cells in the periphery or, within the cord ... The skull bone structure can also be subject to a neoplasm that by its very nature reduces the volume of the intracranial ... Spinal cord and other tissuesEdit. The pons is a specific region in the brainstem that consists of myelinated axons much like ... The medulla oblongata is at the start of the spinal cord and is composed mainly of neuron tissue enveloped in oligodendrocytes ...

https://en.m.wikipedia.org/wiki/Brain_tumor

Then the brain's connection to the cranial nerves and spinal cord are severed, and the brain is lifted out of the skull for ... "Treatable abdominal pathologic conditions and unsuspected malignant neoplasms at autopsy in veterans who received mechanical ...

https://en.m.wikipedia.org/wiki/Autopsy

en:Spinal cord injury (20) *en:Spinal disease (2). *en:Spinal fusion (9) ... en:Neoplasm (40) → 신생물 *en:Nephrotic syndrome (38) → 신증후군 *en:Nervous system disease (4) ...

https://ko.m.wikipedia.org/wiki/위키백과:미번역_문서/의학

... where the terminal part of the spinal arteries does not dilate. This leads to decrease oxygen carried past the maternal villi ... Trophoblastic neoplasms derive from trophoblastic tissue. Examples include: *Choriocarcinoma. *Hydatidiform mole. Mechanism[ ... Nuchal cord. *Obstetrical bleeding *Postpartum. *Pain management during childbirth. *placenta *Placenta accreta ...

https://en.wikipedia.org/wiki/Placental_disease

... but also high risk for disastrous outcomes should bleeding complications occur in eloquent areas of the brain or spinal cord.. ... Myeloproliferative neoplasms including essential thrombocytosis and polycythemia vera[8]. *Chemotherapy[7][19] ... Patients requiring cranial and spinal surgery present a unique situation of elevated risk for VTE ...

https://en.wikipedia.org/wiki/Venous_thrombosis

sampling: fetal tissue (Chorionic villus sampling · Amniocentesis) · blood (Triple test · Percutaneous umbilical cord blood ...

https://kn.wikipedia.org/wiki/ಶಸ್ತ್ರಚಿಕಿತ್ಸೆ

Neoplasms and cancer. *Other *paralytic syndromes. *ALS. *Symptoms and signs *head and neck ...

https://kn.wikipedia.org/wiki/ನಿಕೋಟಿನ್

The muscle relaxant properties of nitrazepam are produced via inhibition of polysynaptic pathways in the spinal cord of ... These were cancers of the brain, lung, bowel, breast, and bladder, and other neoplasms. Not only are benzodiazepines associated ... limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture". J Pharmacol Exp Ther. 244 ... seems to be limited by benzodiazepines effect of slowing recovery of sodium channels from inactivation in mouse spinal cord ...

https://en.wikipedia.org/wiki/Nitrazepam

https://en.wikipedia.org/wiki/Radiation_

... neuropathy and subacute combined degeneration of the cord with resulting balance difficulties from posterior column spinal cord ... and a number of neoplasms of the bone marrow.[1] Causes of increased breakdown include a number of genetic conditions such as ...

https://en.m.wikipedia.org/wiki/Anaemia

... and cord compression: a case report and review of literature»։ The Journal of Spinal Cord Medicine 34 (3): 335-339։ ISSN 1079- ... անգիոմա, անոթային ուռուցք, cardiovascular organ benign neoplasm?[1] և բարորակ ուռուցք ըստ բջջային տեսակի[1]. ...

https://hy.wikipedia.org/wiki/Հեմանգիոմա

... in the ganglia adjacent to the spinal cord (called the dorsal root ganglion) or the trigeminal ganglion in the base of the ... Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ... In some people, shingles can reactivate presenting as zoster sine herpete: pain radiating along the path of a single spinal ... Although DNA analysis techniques such as polymerase chain reaction (PCR) can be used to look for DNA of herpesviruses in spinal ...

https://fa.wikipedia.org/wiki/زونا?match=en

... of nervous tissue is taken from the brain or spinal cord to aid in diagnosis. Biopsy is usually requested after a mass is ... More than 1500 different disorders of the skin exist, including cutaneous eruptions ("rashes") and neoplasms. Therefore, ...

https://en.m.wikipedia.org/wiki/Pathological

Less commonly there may be inflammation of the brain or spinal cord, blood clots, aneurysms, or blindness.[2][1] Often the ... Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...

https://en.wikipedia.org/wiki/Behçet’s_disease

Finally, radicular pain, loss of bowel or bladder control (due to involvement of spinal cord leading to cord compression) or ... "Plasma Cell Neoplasms (Including Multiple Myeloma)-Patient Version". NCI. 1980-01-01. Archived from the original on 27 July ... Involvement of the vertebrae may lead to spinal cord compression or kyphosis. Myeloma bone disease is due to the overexpression ... "Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment". National Cancer Institute. 1980-01-01. Retrieved 28 November ...

https://en.wikipedia.org/wiki/Multiple_myeloma

病灶（英语：Template:Lesions of spinal cord and brain）. *測試 *CSF（英语：Template:CSF tests） ... "Neoplasms and cancer" has been chosen to reflect the fact that not all tumours are benign. The word "cancer" has been included ...

https://zh.wikipedia.org/wiki/Template:Joint_navs

Lesions of spinal cord and brain}}. (none). Lesions of spinal cord and brain. Neurology. Footer. ... Neoplasm. {{Epithelial neoplasms}}. Medicine. Glandular and epithelial neoplasms (ICD-O 8010-8589). Oncology templates. See ... Neoplasm. {{Tumors}}. Medicine. Pathology: Tumor, Neoplasm, Cancer, and Oncology (C00-D48, 140-239). Oncology templates. Footer ... Eye neoplasm (C69/D31, 190/224). Oncology templates. Footer. Pathology. Sense Organs. {{Eponymous medical signs for eyes and ...

https://en.wikipedia.org/wiki/User:Djd/sandbox/MedNav/Pathology_templates

A tumor pressing on the spinal cord may cause weakness, thus an inability to stand, crawl, or walk. ... Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350-9589) (C70-C72, D32-D33, 191-192/225) ... Rare but characteristic presentations include transverse myelopathy (tumor spinal cord compression, 5% of cases), treatment- ...

https://en.wikipedia.org/wiki/Neuroblastoma

Wikipedia:Featured article candidates/Sexuality after spinal cord injury/archive1 (comments left) ... Myeloproliferative neoplasm, Non-alcoholic fatty liver disease, Pericarditis, Paraneoplastic syndrome, Paroxysmal nocturnal ... Spinal cord compression, Spontaneous bacterial peritonitis (T), Thrombotic thrombocytopenic purpura (T, started as an anon), ...

https://en.m.wikipedia.org/wiki/User:Jfdwolff

ICD-9 code 198.3 for Secondary malignant neoplasm of brain and spinal cord is a medical classification as listed by WHO under ... Secondary malignant neoplasm of brain and spinal cord (198.3). ICD-9 code 198.3 for Secondary malignant neoplasm of brain and ... spinal cord is a medical classification as listed by WHO under the range -MALIGNANT NEOPLASM OF OTHER AND UNSPECIFIED SITES ( ...

https://www.aapc.com/codes/icd9-codes/198.3?rf=sc

Experiences with metastatic neoplasms involving the spinal cord. / Barron, Kevin D.; Hirano, Asao; Araki, Shukuro; Terry, ... Barron, K. D., Hirano, A., Araki, S., & Terry, R. D. (1959). Experiences with metastatic neoplasms involving the spinal cord. ... Barron, KD, Hirano, A, Araki, S & Terry, RD 1959, Experiences with metastatic neoplasms involving the spinal cord, Neurology ... Experiences with metastatic neoplasms involving the spinal cord. Neurology. 1959 Feb;9(2):91-106. ...

https://einstein.pure.elsevier.com/en/publications/experiences-with-metastatic-neoplasms-involving-the-spinal-cord-2

Intramedullary Spinal Cord Neoplasms, Primary*Intramedullary Spinal Cord Neoplasms, Primary. *Primary Intramedullary Spinal ... Intradural-Extramedullary Spinal Cord Neoplasms*Intradural-Extramedullary Spinal Cord Neoplasms. *Intradural Extramedullary ... "Spinal Cord Neoplasms" by people in this website by year, and whether "Spinal Cord Neoplasms" was a major or minor topic of ... Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space ...

https://profiles.uchicago.edu/profiles/display/29193

... medical care, Spinal Cord Neoplasm testing, Spinal Cord Neoplasm symptoms and signs, Spinal Cord Neoplasm ... manifestations of the Spinal Cord Neoplasm, Spinal Cord Neoplasm race, Spinal Cord Neoplasm function, Spinal Cord Neoplasm care ... Spinal Cord Neoplasm frequency, what causes Spinal Cord Neoplasm, Spinal Cord Neoplasm prevalence, Spinal Cord Neoplasm role, ... Spinal Cord Neoplasm case study, Spinal Cord Neoplasm diet, Spinal Cord Neoplasm subtypes, Spinal Cord Neoplasm etymology, ...

http://illnessopedia.org/disease-info/spinal-cord-neoplasm-3429/

The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms: a systematic literature review ... The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms : a systematic literature review ... keywords = "Hemangioblastoma, Intramedullary spinal cord neoplasms, Metastasis, Stereotactic radiosurgery",. author = "Silvia ... The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms: a systematic literature review ...

https://miami.pure.elsevier.com/en/publications/the-role-of-stereotactic-radiosurgery-in-the-treatment-of-intrame

Intradural-Extramedullary Spinal Cord Neoplasms; Intramedullary Spinal Cord Neoplasms. On-line free medical diagnosis assistant ... Spinal Cord Neoplasms (Intradural-Extramedullary Spinal Cord Neoplasms; Intramedullary Spinal Cord Neoplasms). Benign and ... Ranked list of diseases related to "Spinal Cord Neoplasms"Drugs, active principles and "Spinal Cord Neoplasms"Medicinal plants ... intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority ...

https://lookfordiagnosis.com/mesh_info.php?term=Spinal+Cord+Neoplasms&lang=1

ICD-10-CM Neoplasms Index References for C72.0 - Malignant neoplasm of spinal cord The ICD-10-CM Neoplasms Index links the ... The ICD code C720 is used to code Spinal tumor Spinal tumors are neoplasms located in the spinal cord. Extradural tumors are ... Malignant neoplasm of spinal cord BILLABLE Billable Code Billable codes are sufficient justification for admission to an acute ... C72.0 is a billable ICD code used to specify a diagnosis of malignant neoplasm of spinal cord. A billable code is detailed ...

https://icd.codes/icd10cm/C720

Fingerprint Dive into the research topics of Experiences with metastatic neoplasms involving the spinal cord. Together they ...

https://einstein.pure.elsevier.com/en/publications/experiences-with-metastatic-neoplasms-involving-the-spinal-cord-2/fingerprints/

Neoplasms, Germ Cell and Embryonal / therapy. Spinal Cord / pathology. Spinal Cord Neoplasms / pathology. Spinal Cord Neoplasms ... Meningeal Neoplasms / therapy. Risk Factors. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / secondary. Spinal Cord ... MeSH-major] Lung Neoplasms / pathology. Spinal Cord / pathology. Spinal Cord Neoplasms / radiotherapy. Spinal Cord Neoplasms / ... Spinal Cord / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / therapy. *[MeSH-minor] Drug Therapy / ...

http://www.bmlsearch.com/?kwr=intramedullary+spinal+cord+neoplasms+primary+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1

Congenital Spinal Malformations Myelomeningocele. Dorsal Dermal Sinus. Tethered Spinal Cord. Neoplasms Sacrococcygeal Teratoma ... and neoplasms; and guidance on limiting the use of ionizing radiation in evaluating pediatric diseases. ...

https://www.elsevier.com/books/imaging-in-pediatrics/merrow-jr/978-0-323-47778-9

Spinal Cord Neoplasms. Germinoma. Paraganglioma, Extra-Adrenal. Neoplasms, Neuroepithelial. Neoplasms by Histologic Type. ... Neoplasms, Glandular and Epithelial. Neoplasms, Nerve Tissue. Neoplasms, Vascular Tissue. Meningeal Neoplasms. ... Recurrent Childhood Spinal Cord Neoplasm Recurrent Childhood Subependymal Giant Cell Astrocytoma Recurrent Childhood ... Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors. ...

https://clinicaltrials.gov/ct2/show/NCT01076530

60 APPLIED LIFE SCIENCES; ALGORITHMS; ESOPHAGUS; HEAD; NAUSEA; NECK; NEOPLASMS; PATIENTS; RADIATION DOSES; SPINAL CORD. ... Other notable relationships included dysphagia/pharyngeal constrictors, nausea/brainstem, nausea/spinal cord, weight-loss/ ...

https://www.osti.gov/scitech/biblio/22407748-mo-brd-data-mining-algorithm-large-scale-analysis-dose-outcome-relationships-database-irradiated-head-neck-hn-cancer-patients

Dose to the spinal cord and brainstem increased by 4.1% and 2.6%, respectively. Mean dose to the parotid glands also increased ... 62 RADIOLOGY AND NUCLEAR MEDICINE; DOSES; GLANDS; HAZARDS; HEAD; NECK; NEOPLASMS; PATIENTS; PLANNING; RADIATION DOSE ... including spinal cord and parotid glands, from the original plan and a comparison plan. Eleven three-dimensional conformal ...

https://www.osti.gov/scitech/biblio/22402336-evaluating-dosimetric-effect-treatment-induced-changes-virally-mediated-head-neck-cancer-patients

Neoplasm of uncertain behavior of brain [glioma]. E08.40, E08.42, E09.40, E09.42, E10.40, E10.42, E11.40, E11.42, E13.40, ... Cervical Spinal Cord Stimulation. *Amirdelfan K, Vallejo R, Benyamin R, et al. High-frequency spinal cord stimulation at 10 kHz ... Spinal Cord Stimulators with Extra Contacts/Leads. Standard spinal cord stimulators use up to 16 contacts/electrodes or up to 2 ... Epidural spinal cord stimulation for the control of spasticity in spinal cord injury patients lacks long-term efficacy and is ...

http://www.aetna.com/cpb/medical/data/100_199/0194.html

Spinal Cord Diseases. Paraneoplastic Syndromes, Nervous System. Nervous System Neoplasms. Neoplasms by Site. Neoplasms. ...

https://clinicaltrials.gov/ct2/show/NCT00445367?term=Acute+Disseminated+Encephalomyelitis&rank=2

New skills are applied daily in this delicate field by the spinal surgeon: this professional can be either an orthopaedic surg ... Spinal surgery is a unique area in the process of continuous development. ... Spinal Cord Neoplasms Luca Denaro, Domenico DAvella. Pages 221-228 * Syringomyelia Luca Denaro, Domenico DAvella ... Spinal surgery is a unique area in the process of continuous development. New skills are applied daily in this delicate field ...

https://link.springer.com/book/10.1007%2F978-3-540-85019-9

Spinal Cord Diseases. Nervous System Neoplasms. Neoplasms by Site. Neoplasms. Neurodegenerative Diseases. ...

https://www.clinicaltrials.gov/ct2/show/NCT01623076?cond=Devic+syndrome&rank=41

Spinal Cord Neoplasms. Spinal Neoplasms. Neoplastic Processes. Pathologic Processes. Neoplasms, Vascular Tissue. Neoplasms by ... Central Nervous System Neoplasms. Nervous System Neoplasms. Neoplasms by Site. Spinal Cord Diseases. Central Nervous System ... Spinal Angiography. Intratumoral Pressure. Vertebral Hemangioma. Spinal Metastasis. Absolute Ethanol. Spinal Tumor. Vertebral ... can press against the spinal cord and interfere with information traveling down from the brain to the nerves of the spinal cord ...

https://www.clinicaltrials.gov/ct2/show/NCT00001417

Adult reconstructive spinal surgery. *Spinal cord neoplasms. *Spinal metastatic disease. *spinal stenosis ... totaling 578 patients with spinal cord astrocytomas. The spinal level of intramedullary spinal cord tumors was predominantly ... and spinal cord injury: a nationwide inpatient sample study SPINAL CORD Veeravagu, A., Jiang, B., Rincon, F., Maltenfort, M., ... Radiologic images showed a bony tumor arising from the C4 lamina with evidence of significant spinal cord compression and cord ...

https://med.stanford.edu/profiles/anand-veeravagu

A Multidisciplinary Approach to Head and Neck Neoplasms EUR [D] 109,99 In den Warenkorb In den Warenkorb ... THE definitive guide on spinal cord injury (SCI) emphasizing state-of-art research*Evidence-based surgical and medical ...

https://www.thieme.de/shop/Neurochirurgie/Fehlings-Vaccaro-Boakye-Essentials-of-Spinal-Cord-Injury-9781604067262/p/000000000261640101

Spinal cord: Congenital malformation.- Infection & inflammation.- Neoplasms.- Miscellaneous.- Head and Neck: Congenital ... Neuroradiology.- Brain: Congenital malformation.- Metabolic disorders.- Infection & inflammation.- Neoplasms.- Trauma & ... Neoplasm.- Mediastinum.- Diffuse or interstitial lung disease?.- Cardiovascular: Introduction.- Congenital malformation.- MR/ ... Neoplasm.- Soft tissue abnormalities.- Trauma (include child abuse).- Miscellaneous.? ...

https://www.chapters.indigo.ca/en-ca/books/radiology-illustrated-pediatric-radiology/9783642355721-item.html

... spinal stroke) are diagnostic challenges. As is the case for the more common cerebrovascular accident affecting cerebral ... The pathologies associated with spinal cord infarction are numerous and include neoplasm, spinal epidural or subdural abscess, ... Spinal Cord Infarction) and Spinal Cord Infarction What to Read Next on Medscape. Related Conditions and Diseases. * Spinal ... Joseph G, Santosh C, Marimuthu R. Spinal cord infarction due to a self-inflicted needle stick injury. Spinal Cord. 2004 Nov. 42 ...

https://emedicine.medscape.com/article/1164217-differential

spinal cord neoplasm. Place of burial. *Literatorskie mostki. Pseudonym. *.....въ (Russian, Cyrillic script) ...

https://commons.wikimedia.org/wiki/%D0%98%D0%B2%D0%B0%D0%BD_%D0%A1%D0%B5%D1%80%D0%B3%D0%B5%D0%B5%D0%B2%D0%B8%D1%87_%D0%A2%D1%83%D1%80%D0%B3%D0%B5%D0%BD%D0%B5%D0%B2

neoplasms (C00-D49). *symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) ... Congenital malformation of spinal cord, unspecified. 2016 2017 2018 Billable/Specific Code POA Exempt Applicable To*Congenital ... Other specified diseases of spinal cord. 2016 2017 2018 Billable/Specific Code *G95.89 is a billable/specific ICD-10-CM code ... Other and unspecified diseases of spinal cord. 2016 2017 2018 Non-Billable/Non-Specific Code Type 2 Excludes*myelitis (G04.-) ...

https://www.icd10data.com/ICD10CM/Codes/G00-G99/G89-G99/G95-/G95.89

Meningeal Neoplasms / therapy. Risk Factors. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / secondary. Spinal Cord ... Ovarian Neoplasms / radiotherapy. Spinal Cord Neoplasms / drug therapy. Spinal Cord Neoplasms / radiotherapy. Spinal Cord ... MeSH-major] Lung Neoplasms / pathology. Spinal Cord / pathology. Spinal Cord Neoplasms / radiotherapy. Spinal Cord Neoplasms / ... Spinal Cord Compression / etiology. Spinal Cord Compression / pathology. Spinal Cord Neoplasms / complications. Spinal Cord ...

http://www.bmlsearch.com/?kwr=metastatic+malignant+neoplasm+to+the+spinal+cord+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1

... refer to a subgroup of intradural spinal tumors that arise from cells within the spinal cord, as opposed to adjacent structures ... Intramedullary spinal cord tumors, like the one depicted in the image below, ... Intramedullary neoplasms and vascular malformations. Clin Neurosurg. 1992. 39:361-87. [Medline]. ... The spinal cord contains the same cell types as the brain, but these are highly specialized to their niche in the spinal cord. ...

https://emedicine.medscape.com/article/251133-overview

Spinal tumors are neoplasms located in the spinal cord. Extradural tumors are more common than intradural neoplasms. Depending ... Spinal cord compression is commonly found in patients with metastatic malignancy. Back pain is a primary symptom of spinal cord ... often causing spinal cord compression, is key to maintaining quality of life in patients. The diagnosis of primary spinal cord ... inside the spinal cord Extramedullary- inside the dura, but outside the spinal cord Extradural tumors are mostly metastases ...

https://en.wikipedia.org/wiki/Spinal_tumor

Spinal Cord Neoplasms • pathology*}, Abstract = {OBJECTIVE: Patients with solitary plasmacytoma in the spine frequently require ... Muscle Neoplasms • Musculoskeletal Diseases • Neoplasm Seeding • Neoplasm Staging • Tomography, X-Ray Computed • anatomy & ... Bone Neoplasms • Humans • Magnetic Resonance Imaging • Soft Tissue Neoplasms • Upper Extremity • anatomy & histology • ... Bone Neoplasms • Humans • Lymphoma, AIDS-Related • Muscle Neoplasms • Muscular Diseases • Myositis • Osteoarthropathy, ...

http://fds.duke.edu/db?pubs-22-58-4910-0--0-1

Adult • Aged • Female • Humans • Magnetic Resonance Imaging* • Male • Middle Aged • Plasmacytoma • Spinal Cord Neoplasms • ...

http://fds.duke.edu/db/aas/BAA/faculty%2520all/nancy.major/publications/133592

Spinal Cord Neoplasms / complications* * Spinal Cord Neoplasms / etiology * Spinal Cord Neoplasms / pathology ... Report: A patient with Klippel-Trenaunay-Weber syndrome who presented with spinal cord compression from a spinal extradural ... Extradural tumor causing spinal cord compression in Klippel-Trenaunay-Weber syndrome Surg Neurol. 1995 Mar;43(3):257-60. doi: ... Background: Myelopathy in Klippel-Trenaunay-Weber syndrome is uncommon but has been reported secondary to spinal vascular ...

https://pubmed.ncbi.nlm.nih.gov/7792689/?dopt=Abstract

As well as testing the therapeutic efficacy of intratumoral ethanol for spinal metastasis, this protocol seeks to elucidate the pathophysiology of pain from spinal metastasis. (clinicaltrials.gov)
The pathologies associated with spinal cord infarction are numerous and include neoplasm, spinal epidural or subdural abscess, granuloma, spinal epidural or subdural hematoma, extramedullary spinal tumor (including meningioma, neurofibroma, extradural lymphoma, metastasis), and herniated intervertebral disk. (medscape.com)
It may prompt a bone scan to confirm or exclude spinal metastasis. (wikipedia.org)
The Feasibility of Spinal Stereotactic Radiosurgery for Spinal Metastasis with Epidural Cord Compression. (bioportfolio.com)
The purpose of this study was to investigate the effectiveness and safety of spinal stereotactic radiosurgery (SRS) in treating spinal metastasis with epidural spinal cord compression (ESCC). (bioportfolio.com)
Introduction: The article describes a clinical case of a malignant tumor of the brain and spinal cord with metastasis, which remained undetected for many years and was treated as syringomyelia. (bioportfolio.com)

Although radiation therapy is currently the treatment of choice for most spinal metastases, radioresistant and recurrent neoplasms remain therapeutic dilemmas. (clinicaltrials.gov)
Because of the debility and shortened life expectancy of patients with spinal metastases, treatment that minimizes blood loss, convalescence, and immobility is critical. (clinicaltrials.gov)
Since most spinal metastases can now be diagnosed with MRI before they produce spinal instability, it may be possible to treat them with direct ethanol infusion while preserving spinal stability. (clinicaltrials.gov)
Depending on their location, the spinal cord tumors can be: Extradural - outside the dura mater lining (most common) Intradural - part of the dura Intramedullary - inside the spinal cord Extramedullary- inside the dura, but outside the spinal cord Extradural tumors are mostly metastases from primary cancers elsewhere (commonly breast, prostate and lung cancer). (wikipedia.org)
Approximately 5%-10% of all patients with cancer have metastases to the spinal column. (ajnr.org)

He was found to have enhancing intramedullary mass lesions in the thoracic spinal cord, and pathology was consistent with an intramedullary germ cell tumor. (hindawi.com)

DRG Group #054-055 - Nervous system neoplasms with MCC. (icd.codes)
Dr. Kondziolka has more experience with Nervous System Neoplasms than other specialists in his area. (healthgrades.com)
Dr. Kondziolka frequently treats Nervous System Neoplasms. (healthgrades.com)
Compare with other Nervous System Neoplasms specialists. (healthgrades.com)

Quantification of spinal cord compression using T1 mapping in patients with cervical spinal canal stenosis - Preliminary experience. (bioportfolio.com)
The differential diagnosis includes spinal cord compression secondary to vertebral fracture or space-occupying lesion, spinal infection or abscess, vascular or hematologic damage, severe disc herniation and spinal stenosis. (aafp.org)

MRI and bone scanning are essential tools in confirming diagnosis of spinal cord neoplasm. (illnessopedia.org)
C72.0 is a billable ICD code used to specify a diagnosis of malignant neoplasm of spinal cord. (icd.codes)
Luo CB, Chang FC, Teng MM. Magnetic resonance imaging as a guide in the diagnosis and follow-up of spinal cord infarction. (medscape.com)
The diagnosis of primary spinal cord tumors is very difficult, mainly due to its symptoms, which tend to be wrongly attributed to more common and benign degenerative spinal diseases. (wikipedia.org)
The diagnosis of primary spinal cord tumors is difficult, mainly due to their symptoms, which in early stages mimic more common and benign degenerative spinal diseases. (wikipedia.org)
The goals of surgical treatment for spinal tumors can include histologic diagnosis, tumor local control or oncological cure, pain relief, spinal cord decompression and restoration of neurological function, restoration of spine stability, and deformity rectification. (wikipedia.org)
Spinal tumor should be considered in the differential diagnosis of dementia and of communicating hydrocephalus. (nih.gov)
Spinal cord emergencies are uncommon, but injury must be recognized early so that the diagnosis can be quickly confirmed and treatment can be instituted to possibly prevent permanent loss of function. (aafp.org)
Contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) have complementary roles in the diagnosis of CNS neoplasms. (oncolink.org)
The 2009 Comprehensive ICD-9-CM Casefinding Code List is designed to assist in casefinding activities that are performed to identify reportable neoplasms, including benign brain and CNS tumors which became reportable in 2004, among a variety of casefinding sources that use ICD-9-CM* codes (modified October 2008) to characterize a diagnosis. (cancer.gov)
These are neoplasm-related secondary conditions for which there should also be a primary diagnosis of a reportable neoplasm. (cancer.gov)
The symptoms of spinal tumors are often non-specific, resulting in a delay in diagnosis. (wikipedia.org)
The diagnosis is challenging, primarily because symptoms often mimic more common and benign degenerative spinal diseases. (wikipedia.org)

Surgical outcome of a posterior approach for large ventral intradural extramedullary spinal cord tumors. (springer.com)
Anatomical location dictating major surgical complications for intradural extramedullary spinal tumors: a 10-year single-institutional experience. (springer.com)

Tumors of the spine can press against the spinal cord and interfere with information traveling down from the brain to the nerves of the spinal cord. (clinicaltrials.gov)
Dr. Veeravagu is focused on advancing minimally invasive surgical techniques for diseases of the spine and cares for patients with a wide range of spinal disorders. (stanford.edu)
Weber P, Vogel T, Bitterling H, Utzschneider S, von Schulze Pellengahr C, Birkenmaier C. Spinal cord infarction after operative stabilisation of the thoracic spine in a patient with tuberculous spondylodiscitis and sickle cell trait. (medscape.com)
Spinal meningiomas derive from arachnoidal cells and most commonly occur within the thoracic segment of the spine. (intechopen.com)
Predicting the risk and severity of acute spinal cord injury after a minor trauma to the cervical spine. (springer.com)
The Torg-Pavlov ratio for the prediction of acute spinal cord injury after a minor trauma to the cervical spine. (springer.com)
Whether cancerous or non-cancerous, tumors in the spine can cause serious health problems as they grow and place pressure on the spinal cord. (spineuniverse.com)
Background: Although pedicle screw placement (PSP) is a well-established technique for spine surgery, the treatment of patients with primary invasive spinal tumor (PIST) has high surgical risks secondary to destroyed pedicles. (thefreelibrary.com)

The use of stereotactic radiosurgery (SRS) for spinal tumors is a recent development, and its application to intramedullary lesions is debated. (elsevier.com)
Degenerative changes of the cervical spinal column are the most common cause of spinal cord lesions in the elderly. (bioportfolio.com)
Lesions in the spinal cord envolved segments of T 1-3 and consisted of severe Wallerian degeneration. (scielo.br)
Lesions gradually diminished towards T 4 and eventually were absent at T 5 and in the more caudal cord segments. (scielo.br)
Focal spinal cord lesions, which can either be neoplastic or non-neoplastic, are rare in children. (appliedradiology.com)
Fortunately, tumors affecting the spinal cord and nerves are rare and are often non-cancerous, benign lesions. (spineuniverse.com)
Damage to the spinal cord often results in a combination of the signs of root lesions (often including pain) at the site of the lesion with signs of damage to tracts below that level. (britannica.com)
Because the fibres cross shortly after they enter the cord, spinothalamic-tract lesions on the left side of the spinal cord lead to loss of sensations on the right side of the body below the lesion. (britannica.com)
As with lesions of the spinal cord, localization of the level of the lesion is determined by noting which of the cranial nerve functions are affected. (britannica.com)

Ependymoma is the most common intramedullary spinal cord neoplasm of glial origin in adults, although its incidence remains relatively rare. (appliedradiology.com)
Spinal cord ependymoma: Radical surgical resection and outcome. (appliedradiology.com)
MR characteristics of histopathologic subtypes of spinal ependymoma. (appliedradiology.com)

The top priority is to exclude spinal cord compression by a mass lesion. (medscape.com)
A patient with Klippel-Trenaunay-Weber syndrome who presented with spinal cord compression from a spinal extradural mass lesion (angiomyolipoma) is described. (nih.gov)
This is not a spinal cord lesion since she has extensive facial involvement. (hawaii.edu)
A midline lesion of the medulla oblongata is likely to involve the pyramidal tracts (the descending motor pathway) and the medial lemnisci (the ascending tracts relaying sensory impulses from the dorsal columns of the spinal cord). (britannica.com)
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)

Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). (uchicago.edu)
Intramedullary neoplasms are often associated with SYRINGOMYELIA. (uchicago.edu)
We conducted a literature search through PubMed's MeSH system, compiling information regarding intramedullary neoplasms treated by SRS. (elsevier.com)
Some 90% to 95% of spinal cord neoplasms are of glial origin, with ependymomas and astrocytomas accounting for up to 70% all intramedullary neoplasms. (appliedradiology.com)

Extradural tumors are more common than intradural neoplasms. (icd.codes)
Illustration of spinal cord tumor locations: intramedullary, intradural-extramedullary, and extradural. (intechopen.com)
There are three main types of spinal tumors classified based on their location: extradural and intradural (intradural-intramedullary and intradural-extramedullary). (wikipedia.org)
Spinal cord tumors are classified based on their location within the spinal cord: intradural (intradmedullary and extramedullary) and extradural tumors. (wikipedia.org)

We present a case of intramedullary sarcoidosis that mimics a tumor of the thoracic spinal cord. (biomedsearch.com)
Magnetic resonance imaging (MRI) demonstrated intramedullary signal within the upper thoracic spinal cord with diffuse enhancement and cord expansion (Figure 1 ). (hindawi.com)
This case report shows an intramedullary thoracic spinal cord abscess secondary to Mycobacterium tuberculosis in a 7-year-old boy with chronic progressive paraparesis and hypesthesia below T10. (ovid.com)

The symptoms seen are due to spinal nerve compression and weakening of the vertebral structure. (wikipedia.org)
The tumoral mass invaded upwards through the bone tissue of the vertebral body into the vertebral canal, compressing the spinal cord and causing Wallerian degeneration at T 1-3 levels of the cord. (scielo.br)
Within the vertebral canal of T 3 , ventral to the spinal cord, two 2.0x1.0x0.5cm soft, dark red, epidural masses, protude from each side of the canal and compressed both sides of the spinal cord. (scielo.br)
The malignant nature of the neoplasm in this case was evident by the invasion of bone tissue of T 3 vertebral body and by the histological aspects. (scielo.br)
It is not only an indicator of bad prognosis but also produces severe pain, spinal instability, and neurologic compression following pathologic vertebral fracture. (ajnr.org)
Spinal tumors are neoplasms located in either the vertebral column or the spinal cord. (wikipedia.org)
Spinal nerve compression and weakening of the vertebral structure cause the symptoms. (wikipedia.org)
The spinal cord is a long, cylindrical anatomical structure that is located within the vertebral cavity. (wikipedia.org)

Myelopathy in Klippel-Trenaunay-Weber syndrome is uncommon but has been reported secondary to spinal vascular malformations. (nih.gov)
Other vascular injuries, infections, developmental and genetic diseases, malnutrition, and inflammation are the causes of nontraumatic spinal cord injury. (springer.com)
Spinal vascular malformations-typical and atypical findings. (springer.com)
Vascular myelopathies-vascular malformations of the spinal cord: presentation and endovascular surgical management. (springer.com)

New skills are applied daily in this delicate field by the spinal surgeon: this professional can be either an orthopaedic surgeon or a neurosurgeon dedicated to the treatment of spinal diseases. (springer.com)
Diseases associated with ZFYVE9 include Spinal Cord Neuroblastoma and Spinal Cord Primitive Neuroectodermal Neoplasm . (genecards.org)
Lioresal is a prescription medication used to alleviate signs and symptoms of muscle spasms caused by multiple sclerosis or spinal cord injuries and other spinal cord diseases. (rxwiki.com)

Primary spinal cord oligodendroglioma is extremely rare. (springer.com)
Schwannomas, meningiomas, and ependymomas (79% of primary spinal tumors). (oncolink.org)
This patient is one of only a handful of reports of a primary spinal germ cell tumor from the western hemisphere (Table 1 ). (hindawi.com)
Reported cases of primary spinal germ cell tumors. (hindawi.com)
sup][1] The incidence of primary spinal tumors has been estimated at 2.5-8.5 per 100,000 people yearly. (thefreelibrary.com)
sup][2],[30] Some primary spinal tumors may not only cause a compressive effect to the cord, but also can destroy the adjacent bony structures due to its invading nature. (thefreelibrary.com)
Primary spinal tumors are associated with a few genetic syndromes. (wikipedia.org)

Abscess and tuberculomas of the spinal cord are rare entities. (ovid.com)

Global incidence of brain and spinal tumors by geographic region and income level based on cancer registry data. (uchicago.edu)
Some suggest that direct decompressive surgery combined with postoperative radiotherapy, provide better outcomes than treatment with radiotherapy alone for patients with spinal cord compression due to metastatic cancer. (wikipedia.org)
Common primary cancers in metastatic spinal tumors includes breast, prostate, lung, and kidney cancer. (wikipedia.org)

Differentiate spinal cord infarction from acute inflammatory demyelinating polyradiculopathy (AIDP, Guillain-Barré syndrome ) by following the diagnostic criteria for AIDP. (medscape.com)

Abnormal nerve sensations like pins and needles, tingling sensation, burning, or itchy sensation (Paresthesia) Pain Numbness Weakness or fatigue Change to movement or motor abilities Incontinence and decreased sensitivity in the buttocks area are regarded as flag signs of a neoplasm compressing the spinal cord. (illnessopedia.org)
Intramedullary spinal cord tumors, like the one depicted in the image below, refer to a subgroup of intradural spinal tumors that arise from cells within the spinal cord, as opposed to adjacent structures such as the nerve roots or meninges. (medscape.com)
Nerve sheath tumors, including schwannomas and neurofibromas, are closely associated with spinal nerves. (intechopen.com)
Thoracic spinal roots may be sacrificed to acquire a total resection, yet cervical and lumbar nerve roots should be preserved prudently. (intechopen.com)
The spinal cord and nerve roots are protected within these structures. (aafp.org)
In the majority of cases, paraplegia results from disease or injury of the spinal cord that causes interference with nerve paths connecting the brain and the muscles. (thefreedictionary.com)
The symptoms and signs of damage to the spinal roots are the same as for peripheral-nerve damage except that the area of involvement is restricted to the area supplied by the spinal roots rather than the nerves. (britannica.com)
ALS is a disease of the motor neurons, those nerve cells reaching from the brain to the spinal cord (upper motor neurons) and the spinal cord to the peripheral nerves (lower motor neurons) that control muscle movement. (encyclopedia.com)
Klekamp J, Samii M. Surgery of spinal nerve sheath tumors with special reference to neurofibromatosis. (springer.com)
Surgical strategies in the Management of Spinal Nerve Sheath Tumors. (springer.com)
Intradural-extramedullary tumors are located within the dura but outside of the spinal cord parenchyma, with the most common being meningiomas and nerve sheath tumors (e.g. schwannomas, neurofibromas). (wikipedia.org)

Pre-clinical spinal cord injury models do not represent the wide range of biomechanical factors seen in human injuries, such as spinal level, injury mechanism, velocity of spinal cord impact, and resi. (bioportfolio.com)
Spinal cord injuries are critical emergencies that must be recognized and treated early to increase the possibility of preventing permanent loss of function. (aafp.org)
The number of nontraumatic spinal cord injuries is increasing as the elderly population increases. (springer.com)
Patients with spinal cord injuries may be placed in traction or the spinal cord may be hyperextended by placing the patient's head at the foot of the bed and adjusting the bed. (thefreedictionary.com)

The vast majority of spinal cord tumors are treated with debulking surgery. (appliedradiology.com)

Astrocytomas affecting the entire cord from the cervicomedullary junction to the conus have been reported in children, leading to the term "holocord astrocytoma. (appliedradiology.com)

This phase I trial is studying the side effects and best dose of vorinostat when given together with temozolomide in treating young patients with relapsed or refractory primary brain tumors or spinal cord tumors. (clinicaltrials.gov)
Primary brain tumors rarely spread to other areas of the body, but they can spread to other parts of the brain and to the spinal axis. (oncolink.org)

Cheshire WP, Santos CC, Massey EW, Howard JF Jr. Spinal cord infarction: etiology and outcome. (medscape.com)

Intradural-intramedullary tumors are located within the dura and spinal cord parenchyma, while intradural-extramedullary tumors are located within the dura but outside the spinal cord parenchyma. (wikipedia.org)

From traumatic brain injury to spinal scoliosis, the ability to capture detailed data regarding clinical symptoms and treatment outcomes has empowered us to do better for patients. (stanford.edu)
Progressive scoliosis, gait disturbance, motor weakness and, most importantly, back pain should raise the possibility of a spinal cord tumor and prompt imaging assessment. (appliedradiology.com)
Children may present with spinal deformities such as scoliosis. (wikipedia.org)

A neoplasm without metastatic potential arising from the anterior or the posterior lobe of the pituitary gland. (icd10data.com)

It is mainly directed towards young surgeons approaching spinal surgery and also to experienced surgeons with regards to complications related to the latest technologies in the spinal field. (springer.com)
A group of patients who underwent spinal surgery with the use of neurophysiological intraoperative monitoring (NIOM) (N = 38) were compared with a group who underwent surgery without NIOM (N = 36), before the introduction of NIOM, and the number of neurological complications was found to be significantly lower in the intramedullary procedure group with NIOM. (medscape.com)
A curable complete resection should be achieved if possible while preserving the nervous function of the spinal cord and minimizing potential complications. (intechopen.com)
The incidence of complications such as skin, bowel, and bladder dysfunction is similar to that of traumatic spinal cord injury, but the incidence of deep vein thrombosis, autonomic dysreflexia, orthostatic hypotension, and pneumonia is significantly less common in nontraumatic spinal cord injury patients compared to traumatic spinal cord injury. (springer.com)
Therefore, preventive measures and careful surgical practice are necessary to avoid complications in treatment of spinal cord tumors. (springer.com)

While a medical student, Dr. Veeravagu worked with neurosurgery and the molecular imaging program to develop novel, non-invasive imaging tools and treatments for malignant neoplasms of central nervous system. (stanford.edu)
Neurosurgery explored the spinal cord at the level of T6 and found a laceration of the cord on the left side at T6. (wikibooks.org)

SuperDEX Trial (Comparison of Two Doses of Dexamethasone for Malignant Spinal Cord Compression Treated by Radiotherapy). (bioportfolio.com)
The study aimed to pilot the viability of a full scale randomised comparison of 2 steroid doses in malignant spinal cord compression, to establish safety of high dose dexamethasone in this. (bioportfolio.com)
This Phase II trial will assess and evaluate the efficacy of re-irradiation in patients presenting with malignant spinal cord compression occurring in a previously irradiation area of spin. (bioportfolio.com)
Radiation therapy may be effective in treating malignant spinal cord compression in patients who have received pre. (bioportfolio.com)

She was treated with dexamethasone to reduce the spinal cord inflammation. (cdc.gov)

Lyders EM, Morris PP. A Case of Spinal Cord Infarction Following Lumbar Transforaminal Epidural Steroid Injection: MR Imaging and Angiographic Findings. (medscape.com)
The purpose of this research study is to look at a combination treatment of radiation therapy and a drug called Abraxane to treat epidural spinal cord compression. (bioportfolio.com)

Spinal cord neoplasm is a growth or tumor located in the spinal cord which can be either benign or malignant. (illnessopedia.org)

Astrocytomas, which are more commonly seen in children than in adults, are also the most common spinal cord neoplasms in children. (appliedradiology.com)
Astrocytomas are infiltrative and eccentric in location, resulting in asymmetric cord expansion. (appliedradiology.com)
Intradural-intramedullary tumors are located within the spinal cord itself, with the most common being ependymomas, astrocytomas, and hemangioblastomas. (wikipedia.org)

Intradural tumours can be classified as intramedullary (within the spinal parenchyma) or extramedullary (within the dura, but outside the spinal parenchyma). (wikipedia.org)
Neuro-oncology deals with the study of brain and spinal cord tumours, which is usually life threatening. (omicsonline.org)
Spinal intradural tumours: part I-Extramedullary. (springer.com)

Intramedullary sarcoidosis is a rare first manifestation of the disease and it can mimic an intramedullary tumor, which is often manifested with symptoms that initiate from spinal cord compression, resulting in paraparesis, sensory disorders and sphincter dysfunction. (biomedsearch.com)
We publish unsolicited papers detailing original work/research that covers the full life span and range of neurological disabilities including stroke, spinal cord injury, traumatic brain injury, neuromuscular disease and other neurological disorders. (iospress.com)

Combarros O, Vadillo A, Gutierrez-Perez R. Cervical spinal cord infarction simulating myocardial infarction. (medscape.com)
In a related case, the authors described the history of a patient who was stabbed in the back of his neck with a knife and who later presented with a Brown-Séquard syndrome attributable to cervical spinal cord damage. (wikibooks.org)
Biomechanics of the cervical spinal cord. (springer.com)

The development or progression of spinal deformity and instability can occur postoperatively, especially in younger patients utilizing multiple level laminectomies, and may necessitate further surgical treatment including spinal fusion and instrumentation. (springer.com)

Spinal cord tumors in children are rare, but they do happen. (spineuniverse.com)

As a resident, Dr. Veeravagu was appointed by the President of the United States as a White House Fellow in 2012, serving as Special Assistant to Secretary of Defense Leon Panetta and Chuck Hagel to guide Department of Defense Policy on traumatic brain injury, spinal cord injury, and mental health treatment for the United States military. (stanford.edu)

Neoplasms of the spinal canal encompass a range of tumors which arise from or involve the spinal cord , theca , and spinal nerves . (radiopaedia.org)
Dorsal rami of the spinal nerves are not shown. (britannica.com)
Lateral" indicates one of the regions of the spinal cord affected, and "sclerosis" describes the hardened tissue that develops in place of healthy nerves. (encyclopedia.com)
These neoplasms do not become cancerous and are not usually life threatening, but depending on its location, a benign growth may cause symptoms and signs if it presses on vital neighboring structures such as glands or nerves. (news-medical.net)

Identifies all reportable neoplasms. (sbcc.edu)

This book offers a comprehensive approach and reviews all of the possible errors encountered by spinal surgeons in the clinical practice. (springer.com)
Tosi L, Rigoli G, Beltramello A. Fibrocartilaginous embolism of the spinal cord: a clinical and pathogenetic reconsideration. (medscape.com)
Weidauer S, Nichtweiss M, Lanfermann H. Spinal cord infarction: MR imaging and clinical features in 16 cases. (medscape.com)
Conventional clinical, electrophysiological and radiological diagnostics of spinal c. (bioportfolio.com)
Clinical and pathological features of bovine lymphoma involving the spinal cord were evaluated through a retrospective study of the necropsy database from 2005 to 2017. (scielo.br)
An animal spinal tumor model is needed to better simulate the clinical situation and to allow percutaneous puncture, which may provide an experimental platform for the new nonvascular interventional therapies. (ajnr.org)
S. hematobium infection of the spinal cord was presumptively diagnosed based on the clinical presentation, exposure history, and positive serology. (cdc.gov)
The most important information in the assessment of a possible spinal cord emergency comes from the history and the clinical evaluation. (aafp.org)

In Reply: Steroid Use Associated With Increased Odds of 30-Day Mortality in Surgical Patients with Metastatic Spinal Tumors in the Setting of Disseminated Disease. (uchicago.edu)

Intramedullary spinal cord tumors are tumors that occur inside the spinal cord. (medscape.com)
Spinal tumors occur with an incidence of 1.1 case per 100,000 persons. (medscape.com)
They occur most often in the cervical region with 44% involving the cervical cord alone and 23% extending into the upper thoracic region. (appliedradiology.com)
These tumors most commonly occur in the retina, cerebellum, and spinal cord. (bartleby.com)
Spinal cord tumors are abnormal mass of tissue that could occur within or adjacent to the spinal cord. (intechopen.com)
This information will help you understand how side effects, such as Neoplasm Malignant, can occur, and what you can do about them. (patientsville.com)
Most symptoms from spinal tumors occur due to compression of the spinal cord as it plays a primary role in motor and sensory function. (wikipedia.org)

As a result, patients with spinal tumors can suffer from loss of movement and sensation within areas of the body below the tumor. (clinicaltrials.gov)
Because of this feature, researchers would like to test the effectiveness of alcohol in treating patients with spinal tumors. (clinicaltrials.gov)

Also, neurological deficits resulting from intramedullary spinal cord tumors are seldom reversible. (medscape.com)
Neurological manifestations are similar to traumatic spinal cord injury, but tend to be older and more frequent in women. (springer.com)
impairment or loss of motor or sensory function in areas of the body served by the thoracic, lumbar, or sacral neurological segments owing to damage of neural elements in those parts of the spinal column. (thefreedictionary.com)

Anatomy33

Organisms4

Diseases36

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Psychiatry and Psychology3

Phenomena and Processes9

Disciplines and Occupations1

Health Care1

Extraneural metastasizing ependymoma of the spinal cord. (1/586)

Recurrent spinal epidural metastases: a prospective study with a complete follow up. (2/586)

Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Phase I Study Group of the Association for Medical Oncology of the German Cancer Society. (3/586)

Diffusion tensor MR imaging and comparative histology of glioma engrafted in the rat spinal cord. (4/586)

Second lung adenocarcinoma after combination chemotherapy in two patients with primary non-Hodgkin's lymphoma. (5/586)

Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. (6/586)

Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2. (7/586)

Management of intramedullary spinal cord tumours: review of 68 patients. (8/586)

Spinal Cord Neoplasms

Spinal Cord

Spinal Cord Injuries

Spinal Cord Diseases

Spinal Cord Compression

Spinal Cord Ischemia

Injections, Spinal

Paraplegia

Spinal Nerve Roots

Spinal Nerves

Motor Neurons

Spinal Cord Regeneration

Spinal Neoplasms

Spinal Canal

Cervical Vertebrae

Anesthesia, Spinal

Quadriplegia

Thoracic Vertebrae

Spinal Diseases

Umbilical Cord

Posterior Horn Cells

Laminectomy

Rats, Sprague-Dawley

Lumbosacral Region

Recovery of Function

Nerve Regeneration

Axons

Spinal Stenosis

Pancreatic Neoplasms

Ganglia, Spinal

Spinal Cord Stimulation

Locomotion

Spinal Fusion

Spinal Injuries

Anterior Horn Cells

Myelitis

Neoplasms

Cordotomy

Immunohistochemistry

Paralysis

Pain

Muscular Atrophy, Spinal

Disease Models, Animal

Neurons

Neoplasms, Cystic, Mucinous, and Serous

Hyperalgesia

Electric Stimulation Therapy

Neuralgia

Myelography

Time Factors

Magnetic Resonance Imaging

Electric Stimulation

Spine

Epidural Space

Afferent Pathways

Urinary Bladder, Neurogenic

Hematoma, Epidural, Spinal

Hindlimb

Neurons, Afferent

Nociceptors

Lumbar Vertebrae

Reflex

Neoplasms, Multiple Primary

Lampreys

Skin Neoplasms

Cats

Motor Activity

Autonomic Dysreflexia

Interneurons

Pyramidal Tracts

Electromyography

Pain Measurement

Tuberculosis, Spinal

Myelin Sheath

Central Nervous System

Fetal Blood

Physical Stimulation

Neuroglia

Contusions

Evoked Potentials, Somatosensory