Spinal Cord Injuries
Spinal Cord
Paraplegia
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Quadriplegia
Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.
Spinal Cord Diseases
Recovery of Function
Spinal Cord Compression
Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.
Cervical Vertebrae
Wounds and Injuries
Autonomic Dysreflexia
A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
Spinal Cord Neoplasms
Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
Spinal Cord Regeneration
Urinary Bladder, Neurogenic
Spinal Cord Ischemia
Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.
Thoracic Vertebrae
Paralysis
Locomotion
Injections, Spinal
Rats, Sprague-Dawley
Electric Stimulation Therapy
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Disease Models, Animal
Injury Severity Score
Pressure Ulcer
Muscle Spasticity
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
Myelitis
Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.
Laminectomy
A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.
Spinal Nerve Roots
Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.
Spinal Nerves
Neuralgia
Electromyography
Pyramidal Tracts
Chondroitin ABC Lyase
Pain
Reperfusion Injury
Spasm
Reflex
Posterior Horn Cells
Neurons in the SPINAL CORD DORSAL HORN whose cell bodies and processes are confined entirely to the CENTRAL NERVOUS SYSTEM. They receive collateral or direct terminations of dorsal root fibers. They send their axons either directly to ANTERIOR HORN CELLS or to the WHITE MATTER ascending and descending longitudinal fibers.
Anterior Horn Cells
Neck Injuries
Neurons
Hindlimb
Gait Disorders, Neurologic
Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.
Ganglia, Spinal
Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.
Myelin Sheath
The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
Oligodendroglia
A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.
Neuronal Plasticity
Evoked Potentials, Somatosensory
Neuroprotective Agents
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Respiratory Paralysis
Hyperalgesia
Neuroglia
The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.
Astrocytes
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Glial Fibrillary Acidic Protein
Urinary Bladder
Umbilical Cord
Walking
Neurologic Examination
Myelography
Spinal Fusion
Rehabilitation Centers
Pain Measurement
Muscle, Skeletal
Immunohistochemistry
Gliosis
Analysis of Variance
Afferent Pathways
Trauma Severity Indices
Reflex, Abnormal
Sensation
Treatment Outcome
Microglia
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
Magnetic Resonance Imaging
Hematoma, Epidural, Spinal
H-Reflex
Rats, Wistar
Efferent Pathways
Spinal Cord Stimulation
Urethra
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Accidents, Traffic
Lumbar Vertebrae
Lung Injury
Evoked Potentials, Motor
Phrenic Nerve
Exercise Therapy
Disability Evaluation
Myelin Proteins
Ejaculation
Activities of Daily Living
Syringomyelia
Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Physical Therapy Modalities
Movement
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
Tibial Nerve
Orthotic Devices
Nerve Fibers, Myelinated
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
Decompression, Surgical
Nociceptors
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Peripheral Nerves
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Ergometry
Cats
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Weight-Bearing
Eye Injuries
Muscular Atrophy, Spinal
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
Sacrum
Central Nervous System
Robotics
Biomechanical Phenomena
Cell Transplantation
Movement Disorders
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
Sciatic Nerve
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
Cells, Cultured
Wallerian Degeneration
Electrodes, Implanted
Interneurons
Functional Laterality
Ependyma
Craniocerebral Trauma
Neural Stem Cells
Neural Conduction
Ischium
Methylprednisolone Hemisuccinate
Nerve Degeneration
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
Neural Prostheses
Wounds, Nonpenetrating
Hyperesthesia
Cauda Equina
Acute Kidney Injury
Man-Machine Systems
Neurotrophin 3
GAP-43 Protein
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Cell Count
Urinary Bladder Calculi
Schwann Cells
Evoked Potentials
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
Adenoviral gene transfer into the normal and injured spinal cord: enhanced transgene stability by combined administration of temperature-sensitive virus and transient immune blockade. (1/4276)
This study characterized gene transfer into both normal and injured adult rat dorsal spinal cord using first (E1-/E3-) or second (E1-/E2A125/E3-, temperature-sensitive; ts) generation of replication-defective adenoviral (Ad) vectors. A novel immunosuppressive regimen aimed at blocking CD4/CD45 lymphocytic receptors was tested for improving transgene persistence. In addition, the effect of gene transfer on nociception was also evaluated. Seven days after treatment, numerous LacZ-positive cells were observed after transfection with either viral vector. By 21 days after transfection, beta-galactosidase staining was reduced and suggestive of ongoing cytopathology in both Ad-treated groups, despite the fact that the immunogenicity of LacZ/Adts appeared less when compared with that elicited by the LacZ/Ad vector. In contrast, immunosuppressed animals showed a significant (P < or = 0.05) increase in the number of LacZ-positive cells not displaying cytopathology. In these animals, a concomitant reduction in numbers of macrophages/microglia and CD4 and CD8 lymphocytes was observed. Only animals that received LacZ/Adts and immunosuppression showed transgene expression after 60 days. Similar results were observed in animals in which the L4-L5 dorsal roots were lesioned before transfection. Gene transfer into the dorsal spinal cord did not affect nociception, independent of the adenovirus vector. These results indicate that immune blockade of the CD4/CD45 lymphocytic receptors enhanced transgene stability in adult animals with normal or injured spinal cords and that persistent transgene expression in the spinal cord does not interfere with normal neural function. (+info)Complete compensation in skilled reaching success with associated impairments in limb synergies, after dorsal column lesion in the rat. (2/4276)
Each of the dorsal columns of the rat spinal cord conveys primary sensory information, by way of the medullary dorsal column nucleus, to the ventrobasal thalamus on the contralateral side; thus the dorsal columns are an important source of neural input to the sensorimotor cortex. Damage to the dorsal columns causes impairments in synergistic proximal or whole-body movements in cats and distal limb impairments in primates, particularly in multiarticulated finger movements and tactile foviation while handling objects, but the behavioral effects of afferent fiber lesions in the dorsal columns of rodents have not been described. Female Long-Evans rats were trained to reach with a forelimb for food pellets and subsequently received lesions of the dorsomedial spinal cord at the C2 level, ipsilateral to their preferred limb. Reaching success completely recovered within a few days of dorsal column lesion. Nevertheless, a detailed analysis of high-speed video recordings revealed that rotatory limb movements (aiming, pronation, supination, etc.) were irreversibly impaired. Compensation was achieved with whole-body and alternate limb movements. These results indicate the following: (1) in the absence of the dorsal columns, other sensorimotor pathways support endpoint success in reaching; (2) sensory input conveyed by the dorsal columns is important for both proximal and distal limb movements used for skilled reaching; and (3) detailed behavioral analyses in addition to endpoint measures are necessary to completely describe the effects of dorsal column lesions. (+info)Effects of spinal cord injury on spermatogenesis and the expression of messenger ribonucleic acid for Sertoli cell proteins in rat Sertoli cell-enriched testes. (3/4276)
The study was an examination of the effects of spinal cord injury (SCI) on spermatogenesis and Sertoli cell functions in adult rats with Sertoli cell-enriched (SCE) testes. The effects of SCI on the seminiferous epithelium were characterized by abnormalities in the remaining spermatogenic cells during the first month after SCI. Three days after SCI, serum testosterone levels were 80% lower, while serum FSH and LH levels were 25% and 50% higher, respectively, than those of sham control SCE rats. At this time, the levels of mRNA for androgen receptor (AR), FSH receptor (FSH-R), and androgen-binding protein (ABP) were normal whereas those for transferrin (Trf) had decreased by 40%. Thereafter, serum testosterone levels increased, but they remained lower than those of the sham control rats 28 days after SCI; and serum FSH and LH levels returned to normal. The levels of mRNA for AR, ABP, and Trf exhibited a biphasic increase 7 days after SCI and remained elevated 28 days after SCI. FSH-R mRNA levels were also elevated 90 days after SCI. Unexpectedly, active spermatogenesis, including qualitatively complete spermatogenesis, persisted in > 40% of the tubules 90 days after SCI. These results suggest that the stem cells and/or undifferentiated spermatogonia in SCE testes are less susceptible to the deleterious effects of SCI than the normal testes and that they were able to proliferate and differentiate after SCI. The presence of elevated levels of mRNA for Sertoli cell FSH-R and AR, as well as of that for the Sertoli cell proteins, in the SCE testes during the chronic stage of SCI suggests a modification of Sertoli cell physiology. Such changes in Sertoli cell functions may provide a beneficial environment for the proliferation of the stem cells and differentiation of postmeiotic cells, thus resulting in the persistence of spermatogenesis in these testes. (+info)Disabling injuries of the cervical spine in Argentine rugby over the last 20 years. (4/4276)
OBJECTIVE: To investigate the incidence and risk factors of disabling injuries to the cervical spine in rugby in Argentina. METHODS: A retrospective review of all cases reported to the Medical Committee of the Argentine Rugby Union (UAR) and Rugby Amistad Foundation was carried out including a follow up by phone. Cumulative binomial distribution, chi 2 test, Fisher test, and comparison of proportions were used to analyse relative incidence and risk of injury by position and by phase of play (Epi Info 6, Version 6.04a). RESULTS: Eighteen cases of disabling injury to the cervical spine were recorded from 1977 to 1997 (0.9 cases per year). The forwards (14 cases) were more prone to disabling injury of the cervical spine than the backs (four cases) (p = 0.03). Hookers (9/18) were at highest risk of injury (p < 0.01). The most frequent cervical injuries occurred at the 4th, 5th, and 6th vertebrae. Seventeen of the injuries occurred during match play. Set scrums were responsible for most of the injuries (11/18) but this was not statistically significant (p = 0.44). The mean age of the injured players was 22. Tetraplegia was initially found in all cases. Physical rehabilitation has been limited to the proximal muscles of the upper limbs, except for two cases of complete recovery. One death, on the seventh day after injury, was reported. CONCLUSIONS: The forwards suffered a higher number of injuries than the backs and this difference was statistically significant. The chance of injury for hookers was statistically higher than for the rest of the players and it was particularly linked to scrummaging. However, the number of injuries incurred in scrums was not statistically different from the number incurred in other phases of play. (+info)Energy cost of propulsion in standard and ultralight wheelchairs in people with spinal cord injuries. (5/4276)
BACKGROUND AND PURPOSE: Wheelchair- and subject-related factors influence the efficiency of wheelchair propulsion. The purpose of this study was to compare wheelchair propulsion in ultralight and standard wheelchairs in people with different levels of spinal cord injury. SUBJECTS: Seventy-four subjects (mean age=26.2 years, SD=7.14, range=17-50) with spinal cord injury resulting in motor loss (30 with tetraplegia and 44 with paraplegia) were studied. METHOD: Each subject propelled standard and ultralight wheelchairs around an outdoor track at self-selected speeds, while data were collected at 4 predetermined intervals. Speed, distance traveled, and oxygen cost (VO2 mL/kg/m) were compared by wheelchair, group, and over time, using a Bonferroni correction. RESULTS: In the ultralight wheelchair, speed and distance traveled were greater for both subjects with paraplegia and subjects with tetraplegia, whereas VO2 was less only for subjects with paraplegia. Subjects with paraplegia propelled faster and farther than did subjects with tetraplegia. CONCLUSION AND DISCUSSION: The ultralight wheelchair improved the efficiency of propulsion in the tested subjects. Subjects with tetraplegia, especially at the C6 level, are limited in their ability to propel a wheelchair. (+info)Heart rate during exercise with leg vascular occlusion in spinal cord-injured humans. (6/4276)
Feed-forward and feedback mechanisms are both important for control of the heart rate response to muscular exercise, but their origin and relative importance remain inadequately understood. To evaluate whether humoral mechanisms are of importance, the heart rate response to electrically induced cycling was studied in participants with spinal cord injury (SCI) and compared with that elicited during volitional cycling in able-bodied persons (C). During voluntary exercise at an oxygen uptake of approximately 1 l/min, heart rate increased from 66 +/- 4 to 86 +/- 4 (SE) beats/min in seven C, and during electrically induced exercise at a similar oxygen uptake in SCI it increased from 73 +/- 3 to 110 +/- 8 beats/min. In contrast, blood pressure increased only in C (from 88 +/- 3 to 99 +/- 4 mmHg), confirming that, during exercise, blood pressure control is dominated by peripheral neural feedback mechanisms. With vascular occlusion of the legs, the exercise-induced increase in heart rate was reduced or even eliminated in the electrically stimulated SCI. For C, heart rate tended to be lower than during exercise with free circulation to the legs. Release of the cuff elevated heart rate only in SCI. These data suggest that humoral feedback is of importance for the heart rate response to exercise and especially so when influence from the central nervous system and peripheral neural feedback from the working muscles are impaired or eliminated during electrically induced exercise in individuals with SCI. (+info)M2 receptors in genito-urinary smooth muscle pathology. (7/4276)
In vitro bladder contractions in response to cumulative carbachol doses were measured in the presence of selective muscarinic antagonists from rats which had their major pelvic ganglion bilaterally removed (denervation, DEN) or from rats in which the spinal cord was injured (SCI) via compression. DEN induced both hypertrophy (505+/-51 mg bladder weight) and a supersensitivity of the bladders to carbachol (EC50=0.7+/-0.1 uM). Some of the SCI rats regained the ability to void spontaneously (SPV). The bladders of these animals weighed 184+/-17 mg, significantly less than the bladders of non voiding rats (NV, 644+/-92 mg). The potency of carbachol was greater in bladder strips from NV SCI animals (EC50=0.54+/-0.1 uM) than either bladder strips from SPV SCI (EC50=0.93+/-0.3 microM), DEN or control (EC50=1.2+/-0.1 microM) animals. Antagonist affinities in control bladders for antagonism of carbachol induced contractions were consistent with M3 mediated contractions. Antagonist affinities in DEN bladders for 4-diphenlacetoxy-N-methylpiperidine methiodide (4-DAMP, 8.5) and para fluoro hexahydrosilodifenidol (p-F-HHSiD, 6.6); were consistent with M2 mediated contractions, although the methoctramine affinity (6.5) was consistent with M3 mediated contractions. p-F-HHSiD inhibited carbachol induced contraction with an affinity consistent with M2 receptors in bladders from NV SCI (pKb=6.4) animals and M3 receptors in bladders from SPV SCI animals (pKb=7.9). Subtype selective immunoprecipitation of muscarinic receptors revealed an increase in total and an increase in M2 receptor density with no change in M3 receptor density in bladders from DEN and NV SCI animals compared to normal or sham operated controls. M3 receptor density was lower in bladders from SPV SCI animals while the M2 receptor density was not different from control. This increase in M2 receptor density is consistent with the change in affinity of the antagonists for inhibition of carbachol induced contractions and may indicate that M2 receptors or a combination of M2 and M3 receptors directly mediate smooth muscle contraction in bladders from DEN and NV SCI rats. (+info)Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. (8/4276)
Upon noxious stimulation, substance P (SP) is released from primary afferent fibers into the spinal cord where it interacts with the SP receptor (SPR). The SPR is located throughout the dorsal horn and undergoes endocytosis after agonist binding, which provides a spatial image of SPR-containing neurons that undergo agonist interaction. Under normal conditions, SPR internalization occurs only in SPR+ cell bodies and dendrites in the superficial dorsal horn after noxious stimulation. After nerve transection and inflammation, SPR immunoreactivity increases, and both noxious as well as nonnoxious stimulation produces SPR internalization in the superficial and deep dorsal horn. We investigated the primary afferent fibers that contribute to enhanced SPR internalization in the spinal cord after nerve transection and inflammation. Internalization evoked by electrical stimulation of the sciatic nerve was examined in untreated animals, at 14 days after sciatic nerve transection or sham surgery and at 3 days after hindpaw inflammation. Electrical stimulation was delivered at intensities to excite Abeta fibers only, Abeta and Adelta fibers or A and C fibers as determined by the compound action potential recorded from the tibial nerve. Electrical stimuli were delivered at a constant rate of 10 Hz for a duration of 5 min. Transection of the sciatic nerve and inflammation produced a 33.7 and 32.5% increase in SPR and immunoreactivity in lamina I, respectively. Under normal conditions, stimulation of Adelta or C fibers evoked internalization that was confined to the superficial dorsal horn. After transection or inflammation, there was a 20-24% increase in the proportion of SPR+ lamina I neurons that exhibited internalization evoked by stimulation of Adelta fibers. The proportion of lamina I SPR+ neurons that exhibited internalization after stimulation of C-fibers was not altered by transection or inflammation because this was nearly maximal under normal conditions. Moreover, electrical stimulation sufficient to excite C fibers evoked SPR internalization in 22% of SPR+ lamina III neurons after nerve transection and in 32-36% of SPR+ neurons in lamina III and IV after inflammation. Stimulation of Abeta fibers alone never evoked internalization in the superficial or deep dorsal horn. These results indicate that activation of small-caliber afferent fibers contributes to the enhanced SPR internalization in the spinal cord after nerve transection and inflammation and suggest that recruitment of neurons that possess the SPR contributes to hyperalgesia. (+info)
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Meta-Analysis of Pre-Clinical Studies of Early Decompression in Acute Spinal Cord Injury: A Battle of Time and Pressure<...
Physiological Responses and Their Regulation During Exercise and Heat Stress in Individuals with Traumatic Spinal cord Injury
Spinal Cord Injury Ring - This ring contains web pages that pertain exclusively to spinal cord injury, spinal cord injury...
Oligodendrogliogenesis and axon remyelination after traumatic spinal cord injuries in animal studies: A systematic review
Types of Spinal Cord Injuries | Hankey Law Office
Second Opinion: Spinal Cord Injury on WXXI-TV/HD | WXXI
Spinal Cord Injury
RHI » Task-Specificity for Incomplete Spinal Cord Injury
Most recent papers with the keyword paraplegia physiotherapy | Read by QxMD
Specialized Rehabilitation for Spinal Cord Injury at HealthSouth Rehabilitation Hospitals
United Spinal Association and National Spinal Cord Injury Association Will Merge | News | Spinal Cord Injury Zone!
Neck Injury ! Spinal Cord Injury
spinal cord injury | Articles related to spinal cord injury | Open Access Journal | Annex Publishers
Spinal Cord Injury Recovery - Page 2 of 62 | Spinal Cord Injury Zone!
Nerve Regeneration Restores Supraspinal Control of Bladder Function after Complete Spinal Cord Injury | Journal of Neuroscience
Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury - Tabular View -...
Spinal Cord Injury Lawyers / Spinal Injury Attorneys | JJS
Pediatric Spinal Cord Injury | Shriners Hospitals for Children
Effect of exercise on disorders of carbohydrate and lipid metabolism in adults with traumatic spinal cord injury: Systematic...
Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury<...
Acute spinal cord injury<...
Prevention of venous thromboembolism in patients with spinal cord injury: Effects of sequential pneumatic compression and...
Gunshot injuries of the spine - A review of 49 cases managed at the Groote Schuur Acute Spinal Cord Injury Unit
Spinal Cord Injury Lawyer - Select Your City
Acute Spinal Cord Injury (SCI) in Children - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Acute Spinal Cord Injury (SCI) in Children - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a...
California Spinal Cord Injury Attorney | San Diego, CA Spinal Cord Injury Lawyer
High-dose methylprednisolone increases risks of complications in acute spinal cord injury | BLOG SOBRE LA PATOLOGIA DEL RAQUIS ...
2020 Spinal Cord Injury Highlight - Utilizing Nerve Transfers to Improve Hand Function Following Cervical Spinal Cord Injury ,...
Alterations in recovery from spinal cord injury in rats treated with recombinant human bone morphogenetic protein-2 for...
What Does a Spinal Cord Injury Lawyer Do? | Premier Law Group
Does physical exercise improve arterial structure and function in spinal cord-injured individuals? And response to letter to...
Loughborough University Institutional Repository: The influence of level of spinal cord injury on the physiological and...
Supplemental materials - The Efficacy and Safety of Mesenchymal Stem Cell Transplantation for Spinal Cord Injury Patients: A...
NextSteps Chicago | Activity Based Therapy Centers | Spinal Cord Injury Rehabilitation
Spinal Cord Injury Rehabilitation Services | HealthBridge
Low-Intensity Wheelchair Training in Inactive People with Long-Term Spinal Cord Injury: A Randomized Controlled Trial on...
Aging | Insulin-like growth factor-1 enhances neuroprotective effects of neural stem cell exosomes after spinal cord injury via...
Spinal Cord Injury Rehabilitation - University of Vermont Medical Center - Burlington, VT
Exertional hypotension in thoracic spinal cord injury: case re...
Spinal Cord/Back Injury - Kansas City and Independence, Missouri | Bottaro, Kubin & Yocum, P.C.
Filing a Personal Injury Claim with a Spinal Cord Injury | Florida Spinal Cord Injury Resource Center
Project Spotlight: Loneliness and Its Relation to Health in People with Spinal Cord Injury
Meaning and components of quality of life among individuals with spinal cord injury in Yogyakarta Province, Indonesia<...
West Palm Beach Spinal Cord Injuries Lawyer | Spinal Cord Injuries Attorneys Serving West Palm Beach, Florida
La Mesa Spinal Cord Injury Lawyer | La Mesa Spinal Cord Injuries Attorney
Assessing the Contribution of Covariance Information to the Electroencephalographic Signals of Brain-Computer Interfaces for...
Spinal Cord Injury Rehabilitation Dayton | The Rehabilitation Institute of Ohio, a joint venture between Premier Health and...
Regional Spinal Cord Blood Flow - How is Regional Spinal Cord Blood Flow abbreviated?
Factsheet 4a: Choosing a Spinal Cord Injury Rehabilitation Facility
Spinal Cord Injury Lawyers | Austin Accident Lawyer
Make wheels a will to win: Indian Spinal Injuries Centre organizes Wheelchair Yoga Session | Pocket Press Release
Closed-Loop Bladder Neuromodulation Therapy in Spinal Cord Injury Rat Model<...
Residency Faculty Receive Multiple Spinal Cord Injury Grants - College of Health Professions and Sciences
The effect of Lycium barbarum on spinal cord injury, particularly its relationship with M1 and M2 macrophage in rats | BMC...
Brain & Spinal Cord Injuries
Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in...
Spinal Cord Injury More Frequent in Children with Seat Belt Injuries - Law Office of Lowell Steiger
Prehospital Protocols Reducing Long Spinal Board Use Are Not Associated with a Change in Incidence of Spinal Cord Injury<...
Spinal cord injury
... spinal cord injury involves preservation of motor or sensory function below the level of injury in the spinal cord. To be ... A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms ... Spinal cord injury without radiographic abnormality exists when SCI is present but there is no evidence of spinal column injury ... "Standard Neurological Classification of Spinal Cord Injury" (PDF). American Spinal Injury Association & ISCOS. Archived from ...
Spinal cord injury research
... seeks new ways to cure or treat spinal cord injury in order to lessen the debilitating effects of ... The theory behind the new spinal cord stimulator is that in certain cases of spinal cord injury the spinal nerves between the ... In 2022, researchers demonstrated a spinal cord stimulator that enabled patients with spinal cord injury to walk again via ... designed for implantation on the surface of the spinal cord, are being studied for paralysis following a spinal cord injury. E- ...
Spinal Cord Injuries Australia
... (SCIA) is a non-government organisation which provides advocacy and services to people with ... Under SCIA's constitution at least 50% of its board of directors must have a spinal cord injury or similar condition. The ... the SCIA online Resource Library provides a wide variety of resources for people with spinal cord injuries and their families, ... A regional information team also provides individual support and advice for people with spinal cord injury in coastal and ...
Rehabilitation in spinal cord injury
According to the Spinal Injuries Association, of 2,494 referrals in 2017-18 to specialist spinal cord injury centres, only 800 ... 2008). "Evaluation of an occupational therapy program for patients with spinal cord injury" (PDF). Spinal Cord. 46 (1): 78-81. ... individuals with a spinal cord injury can greatly benefit from exercise reconditioning. In the majority of cases, spinal cord ... Spinal cord injury research Frood R (2010). "The use of treadmill training to recover locomotor ability in patients with spinal ...
National Spinal Cord Injury Association
20,000 For Spinal Cord Injury Association". Hartford Courant. Retrieved December 26, 2012. "NSCIA". National Spinal Cord Injury ... "Spinal Cord Injury Hot Line Offers Help". The Palm Beach Post. October 18, 1984. Retrieved November 12, 2012. "National Spinal ... The National Spinal Cord Injury Association was a U.S. medical charity that stated its mission was to "is to provide active- ... peer support and advocacy that empowers people living with spinal cord injuries and disorders (SCI/D) to achieve their highest ...
Sexuality after spinal cord injury
University of Alabama at Birmingham Spinal Cord Injury Model System video series Sexuality and spinal cord injury: Where we are ... "Spinal cord injury: An overview". In Field-Fote, E. (ed.). Spinal Cord Injury Rehabilitation. F.A. Davis. ISBN 978-0-8036-2319- ... "Sexuality after spinal cord injury". In Field-Fote, E. (ed.). Spinal Cord Injury Rehabilitation. F.A. Davis. ISBN 978-0-8036- ... "Spinal cord injuries in children and adolescents". In Verhaagen, J.; McDonald III, J.W. (eds.). Spinal Cord Injury: Handbook of ...
Penile implants in spinal cord injury
"Use of penile prostheses to maintain external condom catheter drainage in spinal cord injury patients". Spinal Cord. 30 (5): ... Penile implants may be employed to treat erectile dysfunction or urinary troubles after a spinal cord injury. Penile erection ... Rossier, A. B.; Fam, B. A. (January 1984). "Indication and results of semirigid penile prostheses in spinal cord injury ... "Penile prostheses for the management of the neuropathic bladder and sexual dysfunction in spinal cord injury patients: long ...
Spinal cord injury without radiographic abnormality
... (SCIWORA) is symptoms of a spinal cord injury (SCI) with no evidence of ... A number of underlying mechanisms are proposed including spinal cord contusion, injury to the blood supply to the spinal cord, ... Historical literature regarding spinal cord concussion, spinal cord contusion and hyperextension/hyperflexion injuries to the ... The term SCIWOCTET (spinal cord injury without CT evidence of trauma) was introduced by Martinez-Perez. Finally, the use of ...
Spinal cord
Sometimes the split can be along the length of the spinal cord. Spinal cord injuries can be caused by trauma to the spinal ... Diagrams of the spinal cord. Cross-section through the spinal cord at the mid-thoracic level. Cross-sections of the spinal cord ... spinal cord tumor, spinal stenosis etc.) Globally, it is expected there are around 40 to 80 cases of spinal cord injury per ... The spinal cord with dura cut open, showing the exits of the spinal nerves. The spinal cord showing how the anterior and ...
American Spinal Injury Association
"Spinal Cord Injury Classification". In Fehlings MG, Vaccaro AR, Maxwell B (eds.). Essentials of Spinal Cord Injury: Basic ... Affiliated Societies 13.04.2011 "Standard Neurological Classification of Spinal Cord Injury" (PDF). American Spinal Injury ... "International standards for neurological classification of spinal cord injury". The Journal of Spinal Cord Medicine. 26 Suppl 1 ... "International standards for neurological classification of spinal cord injury (Revised 2011)". The Journal of Spinal Cord ...
Ventral slot
It is hard to foresee the actual outcome on spinal cord injury even with early surgery due to many important facts like animal ... Laminotomy Laminectomy Davis, Emily; Vite, Charles H. (2015). "Spinal Cord Injury". Small Animal Critical Care Medicine. pp. ... The ventral slot technique is a procedure that allows the surgeon to reach and decompress the spinal cord and associated nerve ... This makes possible to decompress the spinal cord from the midline and if necessary to both sides including the leaving nerve ...
Kupenda for the Children
... spinal cord injury; spine curvature disorders; Tourette syndrome; and traumatic brain injury (TBI). Leonard Mbonani, a Kenyan ...
Lumbar anterior root stimulator
Spinal cord injuries have many causes, and result in a high comorbidity. In other words, individuals with spinal cord injuries ... While spinal cord injury is a broad and widely-encompassing term, root stimulators may be used for many instances of SCIs. For ... Similarly, spinal cord injuries can potentially cause a loss of motor control in lower limbs, such as with paraplegic and ... A lumbar anterior root stimulator is a type of neuroprosthesis used in patients with a spinal cord injury or to treat some ...
Syringomyelia
"Spinal Cord Injury , National Institute of Neurological Disorders and Stroke". www.ninds.nih.gov. Retrieved 2022-11-14. ... It is most usually observed in the part of the spinal cord corresponding to the neck area. Symptoms are due to spinal cord ... There are risks of injury to the spinal cord, infection, drainage becoming blocked, and bleeding, and they do not always ... The diagnosis is confirmed with a spinal CT, myelogram or MRI of the spinal cord. The cavity may be reduced by surgical ...
Human brain
ISBN 978-1-475-74997-7. Holtz, Anders; Levi, Richard (July 20, 2010). Spinal Cord Injury. Oxford University Press. ISBN 978-0- ... Motor connections from the brain to the spinal cord, and sensory connections from the spinal cord to the brain, both cross ... Cells at the cephalic end give rise to the brain, and cells at the caudal end give rise to the spinal cord. The tube flexes as ... The pathway fibres travel up the back part of the spinal cord to the back part of the medulla, where they connect with second- ...
Neurogenic shock
It can occur after damage to the central nervous system, such as spinal cord injury and traumatic brain injury. Low blood ... It is found in about half of people who have a spinal cord injury within the first 24 hours, and usually persists for one to ... 2012). "The Incidence of Neurogenic Shock after Spinal Cord Injury in Patients Admitted to a High-Volume Level I Trauma Center ... 2012). "The Incidence of Neurogenic Shock after Spinal Cord Injury in Patients Admitted to a High-Volume Level I Trauma Center ...
Distributive shock
Disordered Cardiovascular Control After Spinal Cord Injury". In Verhaagen, Joost; McDonald, John W. (eds.). Spinal Cord Injury ... normally supported by the sympathetic nervous system due to injury to the central nervous system especially spinal cord injury ...
Powered exoskeleton
"Spinal Cord Injury Medicine. 3. Rehabilitation Phase After Acute Sinap CordInjury". Spinal Cord Injury Medicine. 88. Retrieved ... In medical application, e.g. with complete paraplegia after spinal cord injury, an exoskeleton can be an additional option for ... The CE approval covered the use of HANK for rehabilitation due to Spinal Cord Injury (SCI), Acquired Brain Damage (ABD) & ... "Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon". JNS Journal of ...
Motorcycle fatality rate in U.S. by year
"Spinal cord injury Causes". MayoClinic.org - Mayo Clinic. Retrieved July 16, 2017. "Bridgestone Motorcycle Tires". www. ... Automotive and motorcycle accidents together are the leading cause of spinal cord injuries, about 35% percent. Tire issues such ... Automotive and motorcycle accidents together are the leading cause of spinal cord injuries, about 35% percent; this can include ... more minor injuries to the spinal cord up to more severe cases such paraplegic (2) or quad (4) plegic cases. Paralysis injuries ...
Minister for Medical Research (New South Wales)
... and spinal cord injury. The portfolio was combined with the Health portfolio in 2019 in the second Berejiklian ministry, named ...
The Boy Who Came Back from Heaven
"Eric Westacott Foundation Raises Over $30,000 to Help Young Quadriplegic Boy , News". Spinal Cord Injury Zone. August 11, 2009 ... He suffered various injuries in the accident, including a severe spinal injury, severe neck injuries, and brain trauma, was ...
Duncan Campbell (inventor)
Spinal Cord Injury BC. Winter 2013. p. 30. "Duncan Campbell". BC Sports Hall of Fame. Retrieved 4 November 2019. "Rugby should ...
Injury
Injuries to the nervous system include brain injury, spinal cord injury, and nerve injury. Trauma to the brain causes traumatic ... Injury to the spinal cord is not immediately terminal, but it is associated with concomitant injuries, lifelong medical ... Injuries that cause permanent disabilities, such as spinal cord injuries, can have severe effects on self-esteem. Disfiguring ... though most injuries to the liver are concomitant with other injuries, particularly to the spleen, ribs, pelvis, or spinal cord ...
Brom Wikstrom
Wikstrom sustained an injury to his spinal cord while swimming in the Mississippi River and became a high-level quadriplegic at ... ISBN 978-0-9680667-8-2. "A limit, not an end". Spinal Cord Injury Zone. March 27, 2004 Home & Garden , A Charmed Corner , ...
F8 (classification)
The level of spinal cord injury for this class involves people who have incomplete lesions at a slightly higher level. This ... F8, also SP8, is a standing wheelchair sport classification open to people with spinal cord injuries, with inclusion based on a ... Foster, Mikayla; Loveridge, Kyle; Turley, Cami (2013). "Spinal Cord Injury" (PDF). Therapeutic Recreation. "Special Section ... muscle strength is tested using the bench press for a variety of spinal cord related injuries with a muscle being assessed on a ...
Upper-limb surgery in tetraplegia
Spinal cord injuries are classified as complete and incomplete by the American Spinal Injury Association (ASIA) classification ... Loss of upper-limb function in patients with following a spinal cord injury is a major barrier to regain autonomy. The ... Transfer of the brachio radialis to improve wrist extension in high spinal cord injury. Freehafer AA, Mast WA., J Bone Joint ... Tendons transfers to improve grasp after injuries of the cervical spinal cord.Freehafer AA, Vonhaam E, Allen V., J Bone Joint ...
Magee Rehabilitation Hospital
Spinal Cord Injury Magee Rehabilitation Hospital's spinal cord injury "SCI" program has 4,000 patients and follows up with ... In addition to the main campus that offers comprehensive services for spinal cord injury, brain injury, stroke, orthopaedic ... Horticultural Therapy provides emotional and psychological benefits to patients with spinal cord injuries, brain injuries, ... Life Rolls On utilizes action sports to push the boundary of possibility for those with spinal cord injuries. "They Will Surf ...
Sharon Hovey Wilkin
Dean, Nicholas L. (2008-11-27). "Thankful for 50 more years , News". Spinal Cord Injury Zone!. Retrieved 2022-05-14. "Alumni ... and was a member of the board of directors of the National Spinal Cord Injury Association. She attended the 1990 Rose Garden ... In 1958, as a teenaged exchange student from Chautauqua Central School, she survived a serious spinal injury after falling from ... In 1997, a shoulder injury necessitated her move into a motorized wheelchair, with other powered supports in her Vienna, ...
Hydrostatic shock
Taylor, R. G.; Gleave, J. R. W. (1957). "Incomplete Spinal Cord Injuries". The Journal of Bone and Joint Surgery. British ... This is consistent with other work showing remote spinal cord injuries from ballistic impacts. Roberts et al. present both ... that a focusing effect from concave surfaces can concentrate the pressure wave on the spinal cord producing significant injury ... Distant injuries away from the main track in high velocity missile injuries are very important and almost always present in all ...
David Coulthard
"Spinal Cord Injury Charity". Retrieved 31 August 2012. "Coulthard honoured with MBE". Formula One. 12 June 2010. Archived from ... a charity dedicated to raising awareness of spinal cord injuries. He was unable to finish the race, when his car was hit by ... Coulthard is an ambassador for the spinal injuries charity Wings For Life. He was appointed Member of the Order of the British ... He did not return to the series after suffering a leg injury in a Formula Vauxhall race at Spa-Francorchamps. For 1991, ...
Josh Miller (Arkansas politician)
Since suffering a spinal cord injury in 2003, he has used a motorized wheelchair. "Arkansas State Rep. Josh Miller". Legistorm ... "Josh Miller Rolls into the Arkansas Legislature" (PDF). Spinal Connection. (Articles with short description, Short description ...
Neurorehabilitation
Stroke Spinal Cord Injury Cerebral palsy Parkinson's disease Brain injury Anoxic brain injury Traumatic brain injury Multiple ... other brain or spinal cord injuries the option of training and physical therapy much sooner than might otherwise be possible, ... In case of a serious disability, such as caused by a severe spinal injury or brain damage, the patient and their families' ... Neurorehabilitation is a complex medical process which aims to aid recovery from a nervous system injury, and to minimize and/ ...
Dallas (2012 TV series)
... where he was hospitalized with a spinal cord injury after the Southfork fire) he relents to an experimental spinal cord ... operation which he goes overseas to Tel Aviv where the spinal cord rehab is being experimented. Jude Demorest as Candace Shaw ( ...
Rehabilitation psychology
A variety of empirical studies have demonstrated CBT's effectiveness in cases of traumatic brain injury, spinal cord injury, ... Acquired brain injury Cancer Chronic pain Concussion Limb loss Multiple sclerosis Neuromuscular disorders Spinal cord injury ... "Brief problem-solving training for family caregivers of persons with recent-onset spinal cord injuries: a randomized controlled ... often the result of combat injuries. Advances in medical care had led to an increased number of people surviving injuries and ...
Childbirth
Most fetal birth injuries resolve without long term harm, but brachial plexus injury may lead to Erb's palsy or Klumpke's ... One example of this is the belief in the Chillihuani that if a knife or scissors are used for cutting the umbilical cord, it ... During a C section, the patient is usually numbed with an epidural or a spinal block, but general anesthesia can be used as ... 20 or 30 encounter injuries, infections or disabilities. Most of these deaths and injuries are preventable. In 2008, noting ...
Frenulum of prepuce of penis
For those with spinal cord injuries preventing sensations from reaching the brain, the frenulum just below the glans can be ... It is often a way for those with spinal cord injuries to engage in sexual activities and subsequently feel pleasure. Frenulum ... ISBN 0-534-59567-7. Saulino MF (2006). "Rehabilitation of Persons With Spinal Cord Injuries". WebMD. Pryor JL, LeRoy SC, Nagel ...
Don O. Newland
Newland was rushed to the hospital with severe spinal cord injuries. Newland died May 7 and his body was removed to South Bend ...
Brazil at the 1972 Summer Paralympics
Athletes at the Paralympics in 1972 were all afflicted by spinal cord injuries and required the use of a wheelchair. This is in ... either congenital or sustained through injury or illness; cerebral palsy; wheelchair athletes; visual impairment, including ...
2021 World Artistic Gymnastics Championships
Oldest and youngest competitors Hitomi Hatakeda withdrew due to a neck and spinal cord injury suffered in practice. She was ... diagnosed with neck and spinal cord injury, cervical spine bruise in practice]. Yahoo! Japan (in Japanese). October 20, 2021. ...
Muscle atrophy
... as well as damage to the nervous system such as in spinal cord injury or stroke. Thus, muscle atrophy is usually a finding ( ... Disuse causes rapid muscle atrophy and often occurs during injury or illness that requires immobilization of a limb or bed rest ... It can be caused by immobility, aging, malnutrition, medications, or a wide range of injuries or diseases that impact the ... Given the implications of muscle atrophy and limited treatment options, minimizing immobility is critical in injury or illness ...
Christiaan Bailey
... damaging his spinal cord in the process, which left him paralyzed from the waist down as a result. In 2007, Bailey and Frank ... Since his injury in July 2006, Bailey has gone on to become Captain of USA Surfing, is a three time USA National Champion (2009 ... Since his injury, Bailey's sponsors have continued to support him, giving him the opportunity to surf on tour. He participates ...
CD34
Injection of CD34+ hematopoietic stem cells has been clinically applied to treat various diseases including spinal cord injury ... "Autologous Multiple Injections of in Vitro Expanded Autologous Bone Marrow Stem Cells For Cervical Level Spinal Cord Injury - A ... Cells expressing CD34 (CD34+ cell) are normally found in the umbilical cord and bone marrow as haematopoietic cells, or in ... "Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted ...
Sweden at the 1972 Summer Paralympics
The athletes at the Paralympics in 1972 were afflicted by spinal cord injuries and required the use of a wheelchair. This is in ... either congenital or sustained through injury or illness; cerebral palsy; wheelchair athletes; visual impairment, including ...
Hypoxicator
Studies have also shown that hypoxic air treatment may increase the recovery speed and endurance of spinal cord injuries. There ... Smith, Schevlin (Dec 29, 2013). "Hypoxia May Help Walking Endurance in Spinal Cord Injury Victims". Retrieved 4 November 2014. ...
Jeffrey Macklis
Specific cell types of interest include the following: Corticospinal motor neurons (CSMN), which are lost in spinal cord injury ... Adult neurogenesis Neurodegeneration Neuroregeneration Spinal cord injury research "Jeffrey Macklis, M.D., Dr.Sc.Tech". Harvard ... of endogenous regeneration in the central nervous system which can be applied toward regeneration of the brain and spinal cord ...
1957 in Canada
... paraplegic athlete and activist for people with spinal cord injuries September 10 - Darrell Dexter, politician and 27th Premier ...
Yves De Koninck
Barbara Turnbull Award for spinal cord research, Barbara Turnbull Foundation, CIHR and Brain Canada 2013: Top 10 discoveries of ... Restoring KCC2 function in experimental models with nerve injury conversely restored the threshold. Guillaume Lavertu, first ... suffering from neuropathic pain could be due to a reversal of the mechanisms that suppress pain signals in the spinal cord. The ... "A Spinal Analogue of Memory Reconsolidation Enables Reversal of Hyperalgesia - Fonds de recherche du Québec". Retrieved 29 ...
Paralytic illness of Franklin D. Roosevelt
... and inpatient rehabilitation for amputees and people recovering from spinal cord injuries, brain damage, and stroke. The ... Lovett asked how to distinguish whether paralysis was caused by poliomyelitis or by a clot or lesion of the spinal cord.: 183- ... 58 Keen diagnosed a clot of blood to the lower spinal cord, and prescribed massage of the leg muscles. Eleanor and Howe began ... Paralysis can be determined by test of the spinal fluid.": 66 Eleanor communicated with Keen, who "very strenuously" resisted ...
Hiroyuki Hosoda
Hosoda briefly served as Acting LDP Secretary-General following Sadakazu Tanigaki's hospitalization for a spinal cord injury in ...
Dmitry Shparo
Influenced by Rick Hansen, a Canadian paraplegic athlete and activist for people with spinal cord injuries, Dmitry Shparo ... a ski crossing Greenland by a team including an athlete with spinal cord injury 2002 - an ascent of Mount McKinley, Alaska, at ...
Dominic Thiem
Sinha, Shruti (7 May 2020). "Dominic Thiem participates in charity run for spinal cord research". sportskeeda.com. Retrieved 21 ... He was then set to make his return to the tour at the Córdoba Open in February, but withdrew due to a right finger injury. ... Thiem lost his opener to Matteo Berrettini, and was a set up when Benoit Paire had to retire due to injury in his second match ... On August 18, Thiem announced he was withdrawing for the remainder of the 2021 season due to his wrist injury. Thiem was due to ...
Lists of Canadians
... paraplegic athlete who completed an around-the-world marathon for spinal cord injury research Stephen Lewis CC (born 1937) - ...
Artie Abrams
Artie uses a wheelchair due to a spinal cord injury he sustained in a car crash at the age of eight. His storylines have seen ... She later presents him with research on the progress of spinal cord injury treatments, raising Artie's hopes that he may soon ...
Mikheyev v. Russia
... the fall resulted in a spinal cord injury that rendered him a paraplegic. On the evening of September 8, 1998, 22-year-old ... with a crush of spinal cord and other injuries. On the same day - September 19, 1998 - Maria Savelyeva returned home by herself ...
Wand vibrator
"Treatment of infertility in men with spinal cord injury". Nature Reviews Urology. 7 (3): 162-172. doi:10.1038/nrurol.2010.7. ...
Sam Schmidt Paralysis Foundation
Paralysis and spinal cord injuries cost the U.S. health care system billions of dollars each year. Spinal cord injury costs ... There are 50,000 wounded or injured soldiers from the wars in Iraq and Afghanistan and many have suffered spinal cord injuries ... To cure paralysis and loss of function that spinal cord injuries cause, doctors will need a carefully orchestrated series of ... Over 50% of people with paralysis and over 62% of people with spinal cord injury live in poverty. ...
Max Ramsay
Shane and Danny are involved in a car accident in which Shane suffers a ruptured spleen and a spinal-cord injury, which ends ... A back injury and difficulty getting into character also influenced Bell's decision to leave the show. He found the role was no ... A back injury also influenced Bell's decision to leave the show. He said; "I was considering resigning before my back problems ... When Danny tells his father he wishes he had Shane's injuries, Max agrees with him but he later tells his friend and neighbour ...
Eric LeGrand
On October 16, 2010, LeGrand had severe spinal cord injury during a game against Army in East Rutherford, New Jersey, at ... The Eric LeGrand Patriot Saint Foundation is dedicated to helping those with spinal cord injuries. Nike presented their Eric ... On October 16, 2016 (the sixth anniversary of his spinal cord injury), Avenel, NJ's former Fifth District Park was rededicated ... he proved to be a crucial performer at defensive tackle in the first six games before having career-ending spinal cord injury. ...
Anouk Taggenbrock
When she was 13 years old she received a spinal cord infection that resulted in a spinal cord injury. She studied at the ...
Spinal Cord Injuries: Practice Essentials, Background, Anatomy
Patients with spinal cord injury usually have permanent and often devastating neurologic deficits and disability. ... is an insult to the spinal cord resulting in a change, either temporary or permanent, in its normal motor, sensory, or ... See also Hypercalcemia and Spinal Cord Injury, Spinal Cord Injury and Aging, Rehabilitation of Persons With Spinal Cord ... Spinal cord injury (SCI) is an insult to the spinal cord resulting in a change, either temporary or permanent, in the cords ...
Spinal cord injury: MedlinePlus Medical Encyclopedia Image
Spinal cord damage also causes loss of reflex function below ... A severe spinal cord injury often causes loss of feeling and ... In the event of a spinal injury prompt medical attention can help to minimize further spinal cord damage. ... A severe spinal cord injury often causes loss of feeling and paralysis, the loss of movement and voluntary control over the ... Spinal cord damage also causes loss of reflex function below the point of injury interrupting bodily functions such as ...
Acute Traumatic Spinal Cord Injury Surveillance --
United States, 1987
... recommended designating traumatic spinal cord injuries (SCIs) as the first injury condition reportable to state health agencies ... Ergas Z. Spinal cord injury in the United States: a statistical update. Cent Nerv Syst Trauma 1985;2:31-2. *NSCIA is a private ... Acute Traumatic Spinal Cord Injury Surveillance -- United States, 1987 In 1987, the Council of State and Territorial ... Reported by: the Spinal Cord Injury Program, Div of Vocational Rehabilitation, Dept of Labor and Employment Security, ...
New Discovery May Aid Treatment of Spinal Cord Injuries
... and may pave the way for treatments of spinal cord injuries. ... by researchers may provide insights into how the spinal cord ... New Discovery May Aid Treatment of Spinal Cord Injuries. A discovery by researchers at University of Minnesota may provide new ... Unique Scaffolding Material Shows Promise in the Treatment of Spinal Cord Injury ... our studies may help to identify treatments for Parkinsons patients and those with spinal cord injury, said Mesce. ...
Neurological and functional recovery after thoracic spinal cord injury
Persons who are older at the time of injury have poorer functional recovery than younger persons. Conversion to a better AIS ... Setting: Spinal Cord Injury Model Systems. Participants: Six hundred sixty-one subjects enrolled in the Spinal Cord Injury ... Neurological and functional recovery after thoracic spinal cord injury J Spinal Cord Med. 2016;39(1):67-76. doi: 10.1179/ ... Outcome measures: American Spinal Injury Association Impairment Scale (AIS) grade, sensory level (SL), lower extremity motor ...
Spinal Cord Injuries: Practice Essentials, Background, Anatomy
Patients with spinal cord injury usually have permanent and often devastating neurologic deficits and disability. ... is an insult to the spinal cord resulting in a change, either temporary or permanent, in its normal motor, sensory, or ... See also Hypercalcemia and Spinal Cord Injury, Spinal Cord Injury and Aging, Rehabilitation of Persons With Spinal Cord ... Spinal cord injury (SCI) is an insult to the spinal cord resulting in a change, either temporary or permanent, in the cords ...
Spinal Cord Injury Symptoms, Signs & Causes
Learn about symptoms and signs associated with spinal cord injury. Associated symptoms and signs include paralysis of the legs ... Causes of spinal cord injury. Trauma is the most common cause of spinal cord injury. The condition can also occur due to loss ... Main Article on Spinal Cord Injury Symptoms and Signs. * Spinal Cord Injury: Treatments and Rehabilitation. When vertebrae are ... Spinal cord injury is any type of damage or injury to the spinal cord, the collection of nerves that begin at the brain and ...
Reticular formation and spinal cord injury | Spinal Cord
Clinical considerations discus commonly encountered problems of spinal cord injury service and science. Every clinical ... 3) Spinal cord RF is located in the intermediolateral zone. It sends ascending and receives descending signals to coordinate ... spinal cord repair and comprehensive management are discussed to enlighten the clinical importance of the RF. ... A two-part pilot study of sildenafil (Viagra™) in men with erectile dysfunction caused by spinal cord injury. Spinal Cord 1999 ...
Spinal Cord Injuries - Is there now a cure? - ABC
Rod Quinn and Dr James St John from Griffith University discuss the present and future for those suffering from spinal cord ... injury, in the immediate wake of Polands successful surgery resulting in a paralysed man learning to walk again. ... Spinal Cord Injuries - Is there now a cure?. Broadcast. Fri 24 Oct 2014 at 10:00pm. Friday 24 Oct 2014 at 10:00pm. Fri 24 Oct ... Quinn and Dr James St John from Griffith University discuss the present and future for those suffering from spinal cord injury ...
Spinal Cord Injury Resource Center
Lily's Legs is fundraising for Spinal Cord Injuries Australia (SCIA)
spinal cord injury Archives - Punch Newspapers
Spinal Cord Injuries | MomsTeam
The way to prevent concussions and serious head and spinal injuries in football is for parents to make sure that coaches are ... While Jablonskis injury was, of course, his parents worst nightmare, and will change his life forever, such injuries are ... Preventing Head Injuries in Football: No Tackling With Crown Of Helmet!. Submitted by Bobby Hosea on Wed, 06/27/2012 - 20:43. ... In the four years I have been sharing my expertise on how to prevent helmet-crown related injuries in football, there has been ...
Spinal cord injury - Care at Mayo Clinic - Mayo Clinic
Learn more about what happens after your spinal cord has been damaged. ... Spinal cord injury care at Mayo Clinic. * Your Mayo Clinic care team. Mayo Clinic doctors and staff have helped thousands of ... people recover from spinal cord injuries and diseases. Mayo Clinics spinal cord injury team is led by doctors trained in brain ... Experience. Every year, more than 73,000 people receive care for spinal cord injuries and diseases from doctors and other ...
Spinal Cord Injury: Flexibility Exercises | HealthLink BC
A spinal cord injury (SCI) makes movement difficult. Movement is what keeps your muscles and joints flexible and helps prevent ... A spinal cord injury (SCI) makes movement difficult. Movement is what keeps your muscles and joints flexible and helps prevent ... may be convenient to do your stretches in the morning or evening at the same time you inspect your skin for pressure injuries. ... Spinal Cord * Spinal Cord Injury: Flexibility Exercises * Multiple Sclerosis: Benefits of Exercise ...
Aging Diminishes Spinal Cord Regeneration After Injury
... the brains communication wires in the spinal cord. The study is published March 31 in Cell Reports. ... Aging Diminishes Spinal Cord Regeneration After Injury Mouse study may inform new strategies to treat spinal cord injury in ... In mammals, axons in the brain and spinal cord are limited in their ability to regenerate after injury. This is true even in ... In other words, middle-aged adults, the peak age group for people living with a paralyzing spinal cord injury today, already ...
Browsing by Subject "Spinal Cord Injuries"
International perspectives on spinal cord injury : summary Bickenbach, Jerome; Officer, Alana; Shakespeare, Tom; von Groote, ... International perspectives on spinal cord injury / edited by Jerome Bickenbach ... [et al] ... Promoting independence following a spinal cord injury : a guide for mid-level rehabilitation workers ... Bickenbach, Jerome; Officer, Alana; Shakespeare, Tom; von Groote, Per; World Health Organization; The International Spinal Cord ...
Exercise and Spinal Cord Injury - United Spinal Resources
Frontiers | Endocrine Therapy for the Functional Recovery of Spinal Cord Injury
Spinal cord injury (SCI) is a major cause of physical disability and leads to patient dissatisfaction with their quality of ... Spinal cord injury (SCI) is a major cause of physical disability and leads to patient dissatisfaction with their quality of ... Spinal cord injury (SCI) is a devastating nerve injury caused by severe trauma to the spinal cord, leading to temporary or ... Primary injury to the spinal cord is caused by the initial direct compression or contusion of the spinal cord, which results in ...
Leisure - Spinal Cord Injury Model System | UAB
UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of race, national origin, age, genetic or family medical history, gender, faith, gender identity and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans ...
Spinal Cord Injury: Signs and Symptoms | Buzz
So, read on to recognise the signs and symptoms of a spinal cord injury. ... A spinal cord injury should not be confused with back pain. ... A spinal cord injury should not be ignored. But, what if you ... read on to recognise the signs and symptoms of a spinal cord injury.. Spinal cord injury symptoms:. 1) Loss of cognitive ... But in case of an accident, the case of spinal cord injury is far more intense, here are the symptoms to look for:. 1) Intense ...
Go to Spinal Cord Injury.
Spinal Cord Injury. 2018. Abstract:. Acute spinal cord injury (SCI) is presented in two phases - primary phase of mechanical ... There is currently no standard to measure blood flow in the spinal cord. The ability to monitor mean arterial pressure (MAP) ... Less than 5% of patients afflicted with acute SCI with Grade A injuries exhibit improvement. Patients of SCI can be subject to ... Costs are incurred from the spinal surgery, rehabilitation, medication, medical equipment, and long-term care. Effectively ...
Potential for exciting new treatment for spinal cord injury | News | The University of Aberdeen
New research from the University of Aberdeen has found a new way to repair injured spinal nerves. ... Dr Shewan explained: "Adult spinal nerve cells have very limited ability to regrow which makes recovery from spinal cord injury ... "Currently there is no cure for spinal cord injury, so our mission is to find better strategies to help the injured spinal ... "The use of self-assembling hydrogel technology in spinal cord injury is relatively new and if it were to be used by ...
Bull Riding-Related Brain and Spinal Cord Injuries -- LA, 94-95
Bull Riding-Related Brain and Spinal Cord Injuries -- Louisiana, 1994-1995 ... A spinal cord injury resulting in any preserved motor or sensory function below the level of the injury. POINT OF CONTACT FOR ... He sustained an incomplete T10-T11 spinal cord injury, multiple rib fractures, a tension pneumothorax, and a splenic injury. He ... Bull Riding-Related Brain and Spinal Cord Injuries -- Louisiana, 1994-1995 MMWR 45(37);796-798 Publication date: 09/20/1996. ...
Craig Spinal Cord Injury Support Group - Craig Hospital
... specializes in the neuro-rehabilitation and research of patients with spinal cord injuries and traumatic brain injuries. ... The purpose of this group is to offer peer support and meet other caregivers who have a loved one with a spinal cord injury ( ... The purpose of this group is to offer peer support and meet others with spinal cord injury (SCI). The group consists of SCI ... Craig Spinal Cord Injury Support Group. Craig Spinal Cord Injury Support Group ...
Clinical Trial of Stem Cells for Spinal Cord Injury Cleared by FDA | MedPage Today
... one that is aimed at remyelinating injured spinal cords, Geron announced here. ... Clinical Trial of Stem Cells for Spinal Cord Injury Cleared by FDA. by John Gever, Senior Editor, MedPage Today January 23, ... Tacrolimus has shown some ability on its own to restore spinal cord function after injury in rat models. Dr. Okarma said this ... Eight to 10 patients with complete, grade A spinal cord injuries will be given single injections of oligodendrocyte progenitor ...
DARPA Awards $36M for Spinal Cord Injury Recovery Systems | BioScan | Jan/Feb 2021 | BioPhotonics
DARPABusinessfundingawardsspinal cord injuriesspinal cord repairbiomedical imagingspectroscopynear infrared spectroscopy ... and nonprofit organizations an award that supports the consortiums development of interventions for spinal cord injuries. The ... The additional technologies include an implantable mean arterial pressure sensor and a spinal cord stimulation and blood ... will then commercialize the device to assess blood oxygenation and blood flow at the site of spinal injury. ...
Spinal cord injuries news and latest updates
All the latest science news about spinal cord injuries from Phys.org ... Spinal cord injury. Spinal cord injuries cause myelopathy or damage to white matter or myelinated fiber tracts that carry ... Promoting axon regeneration in the zebrafish spinal cord. After an injury to the spinal cord, patients often remain paralyzed ... How stem cells synchronize to repair the spinal cord in axolotls. The spinal cord is an important component of our central ...
nerve regeneration | Spinal Cord Injury Information Pages
Epigenetic Treatment in Mice Improves Spinal Cord Regeneration After Injury. *Restoring Movement After Spinal Cord Injury Focus ... Stem Cell Grafts and Rehabilitation Combined Boost Spinal Cord Injury Results. Posted on October 29th, 2022 ... Read more of Stem Cell Grafts and Rehabilitation Combined Boost Spinal Cord Injury Results » ... Stem Cell Treatment Repairs Spinal Cord Injuries In Paralyzed Dogs. Posted on November 25th, 2012 ...
Acute Spinal Cord Injury (Trauma) | Upstate Neurological Institute | SUNY Upstate Medical University
Traumatic spinal cord injury. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/traumatic-spinal-cord- ... Acute Spinal Cord Injuries are treated at Upstate Brain and Spine Center. ... www.dynamed.com/management/management-of-chronic-spinal-cord-injury. Accessed February 24, 2021. ... Management of chronic spinal cord injury. EBSCO DynaMed website. Available at: https:// ...
AcuteParalysis20222021Complete spinalAmerican Spinal Injury AssociationNervesMajority of spinal cord injSeverityAcademy of Spinal Cord Injury ProfessiNeurologicalParaplegiaPatientsTraumaThoracicContusionTypes of Spinal Cord InjResearchersCatastrophicSCIsLesionsLive with spinal cord injSymptoms of a spinal cord iInternational Spinal Research TrustPersons with spinal cord iIndividuals with spinal cord iChronic spinal cord iTreatmentsIncidenceBladderRats with spinal injuryDamage to the spinal cordRegenerationTreatmentFractures2018AccidentsLevel of the spinalVertebrae2016SecondaryBrainCervical spinalSurgeryEpidemiologyIncomplete spinalPeopleNerve fibersDysfunctionNeuralRehabilitation MedicineSevere spinalCause spinalNeckStimulationFunctional recoveryMortality
Acute17
- Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. (medscape.com)
- 2. Acute care management of traumatic and nontraumatic injury. (medscape.com)
- Blood pressure management after acute spinal cord injury. (medscape.com)
- Estimates of the incidence of acute traumatic SCI in the United States range between 28 and 50 injuries per million persons per year (1). (cdc.gov)
- Epidemiological aspects of acute spinal cord injury: a review of incidence, prevalence, causes, and outcome. (cdc.gov)
- The clinical assessment of pulmonary function in acute spinal cord injury begins with careful history taking regarding respiratory symptoms and a review of underlying cardiopulmonary comorbidity such as chronic obstructive pulmonary disease (COPD) or heart failure. (medscape.com)
- Acute spinal cord injury (SCI) is presented in two phases - primary phase of mechanical trauma and secondary phase, chronic, local hypotension. (jhu.edu)
- Less than 5% of patients afflicted with acute SCI with Grade A injuries exhibit improvement. (jhu.edu)
- What is an acute spinal cord injury? (ahealthyme.com)
- Acute spinal cord injury (SCI) is a traumatic injury that bruises, partially or completely tears the spinal cord. (ahealthyme.com)
- Sometimes, surgery is needed to stabilize the spinal cord after acute SCI. (ahealthyme.com)
- Previous studies have demonstrated reduced lesion and scarring, tissue sparing and functional recovery after acute spinal cord injury," said Tuszynski, who also has an appointment with the Veterans Affairs Medical Center, San Diego. (news-medical.net)
- Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages. (ox.ac.uk)
- Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)
- Physical and occupational therapy should be initiated within 1 week after injury for acute SCI patients who are determined to be medically ready. (medscape.com)
- This first case is part of a pilot study to measure the clinical safety of the implanted device developed by InVivo Therapeutics Holdings Corp. If proven successful, surgeons believe the new technique could become a standard protocol in the treatment of acute spinal cord injury. (dignityhealth.org)
- This could be the first step in identifying a new treatment option to improve the overall recovery of individuals with acute spinal cord injury. (dignityhealth.org)
Paralysis11
- An injury to the upper portion of the spinal cord in the neck can cause quadriplegia ( paralysis of both arms and both legs). (medicinenet.com)
- The animal experiments also showed that locomotor function could be partially restored after spinal cord injury that, in untreated animals, caused complete and permanent paralysis. (medpagetoday.com)
- Spinal injuries vary in intensity, from a bulging disc that could be causing zero pain to a herniated disc(s) that might be pressing against your spinal cord or a nerve root ending causing numbness, tingling, radiating pain and, in the most severe cases, paralysis. (neufeldlawfirm.com)
- Pain is a particularly important problem after spinal cord injury since the type of pain that ensues after a spinal cord injury is considered even more debilitating than the paralysis itself. (medindia.net)
- iAM ABLE helps close the gap between traditional therapy and specialized therapy for those with spinal injuries and paralysis. (nbcmiami.com)
- By using the experience of what he went through, Iglesias created iAM ABLE as a one-stop shop to close the gap between traditional therapy and specialized therapy for those with spinal injuries and paralysis. (nbcmiami.com)
- iAM ABLE is a facility and project that somebody can come to after sustaining a neurological injury, whether it's paralysis from a traumatic brain injury or a spinal cord injury and they can come to find specialized activity-based therapy, they can find mentorship and our resource center," said Iglesias. (nbcmiami.com)
- Additionally, paralysis caused by a spinal cord injury might be referred to as tetraplegia or paraplegia, depending on the areas that are affected. (cantorinjurylaw.com)
- Those who suffer spinal cord injuries often suffer myriad adverse effects, including possible paralysis, organ damage or loss of motor skills. (woodlandsinjurylawyer.com)
- Paralysis from spinal cord reperfusion effect - this is an uncommon complication that causes a stroke-like effect in the spinal cord. (singhealth.com.sg)
- During a car accident it's possible for spinal nerves below the area of injury to become partially or fully cut off from the brain, which can lead to paralysis of limbs or areas of the body. (hastingsdirect.com)
20221
- Cite this: Management of Spine Injury Clinical Practice Guidelines (ACS, 2022) - Medscape - Apr 01, 2022. (medscape.com)
20211
- Science Saturday: Regenerative pipeline for spinal cord repair July 31, 2021, 07:00 a.m. (mayoclinic.org)
Complete spinal4
- With a complete spinal cord injury, the cord can't send signals below the level of the injury. (medlineplus.gov)
- Definition of complete spinal cord injury. (medscape.com)
- In complete spinal cord injury, there is no function below the level of injury. (medicinenet.com)
- Complete bilateral loss of sensation or motor function below a certain level indicates a complete spinal cord injury. (medscape.com)
American Spinal Injury Association4
- American Spinal Injury Association. (medscape.com)
- American Spinal Injury Association Impairment Scale (AIS) grade, sensory level (SL), lower extremity motor scores (LEMS), and FIM. (nih.gov)
- In a study showing a high incidence of autonomic dysfunction, including orthostatic hypotension and impaired cardiovascular control, following spinal cord injury, it was recommended that an assessment of autonomic function be routinely used, along with American Spinal Injury Association (ASIA) assessment, in the neurologic evaluation of patients with spinal cord injury. (medscape.com)
- The vast majority of penetrating spinal cord injuries (SCIs) result in complete (American Spinal Injury Association [ASIA] A) injuries. (medscape.com)
Nerves10
- Your spinal cord is a bundle of nerves that runs down the middle of your back. (medlineplus.gov)
- Spinal cord injury is any type of damage or injury to the spinal cord, the collection of nerves that begin at the brain and travel down the back encased in the vertebrae. (medicinenet.com)
- New research from the University of Aberdeen has found a new way to repair injured spinal nerves. (abdn.ac.uk)
- Researchers achieved significant regrowth of injured spinal nerves in rats when they activated a specific molecule found in nerve cells. (abdn.ac.uk)
- Dr Wenlong Huang, Dr Derryck Shewan and Dr Alba Guijarro-Belmar from the Institute of Medical Sciences found that activation of a molecule called Epac2 resulted in significant improvement in the regrowth of nerves that had been severed following spinal cord injury. (abdn.ac.uk)
- The injured spinal nerves not only regenerated more robustly, they sensed the surrounding environment was not as inhibitory anymore, so the damaged nerves could more successfully regrow and cross the injury site. (abdn.ac.uk)
- Dr Huang explains: "Currently there is no cure for spinal cord injury, so our mission is to find better strategies to help the injured spinal nerves to regrow. (abdn.ac.uk)
- The spinal cord is a bundle of nerves that carries messages between the brain and the rest of the body for movement and sensation. (ahealthyme.com)
- It has been demonstrated that after a spinal cord injury the nerves below the lesion do not become silent but maintain their functional properties and still are able to respond to stimulus. (calgaryfoundation.org)
- Male products can help men overcome erectile dysfunction, following prostate surgery or treatment, diabetes, heart disease, spinal cord injury and neurological conditions by promoting the blood flow into the erectile tissues and stimulating the nerves to help the man have an erection without them having to take Viagra. (goodhousekeeping.com)
Majority of spinal cord inj2
Severity10
- According to the severity of clinical symptoms, SCI can be divided into complete injury and incomplete injury. (frontiersin.org)
- Treatment depends on the cause, severity, or location of the injury. (upstate.edu)
- While many spinal cord injuries are immediately known and felt after the accident, they can also vary in severity and some victims may not realize they have an injury until hours or days after their accident. (bradmclelland.com)
- The severity of a spinal cord injury also depends on how badly the cord is damaged and where the injury is location. (bradmclelland.com)
- Incomplete spinal cord injury recovery time may vary depending on the level of injury, severity, and rehabilitation process. (flintrehab.com)
- There are three factors that can continue improving after this initial phase, and they are the severity of your injury, the level of your injury , and your functional abilities. (flintrehab.com)
- These factors can affect our understanding of the prevalence, incidence, and costs of MSD aside from the variability of actual prevalence or incidence rates due to etiologic issues or costs due to illness or injury severity or treatment response and recovery. (cdc.gov)
- Depending on the location and severity of their spinal injury, you may help them with bathing, dressing, toileting, changing positions to prevent bed sores, preparing meals, managing pain and following a physical therapy regimen. (onteenstoday.com)
- The severity of injuries depends on lots of things, for example speed, seatbelt use, what the car made contact with, and the safety features of the cars involved. (hastingsdirect.com)
- Due to the severity of this type of injury, especially among the young, effective preventive efforts may be necessary. (who.int)
Academy of Spinal Cord Injury Professi1
- Additional information can be found through the Academy of Spinal Cord Injury Professionals . (nrmp.org)
Neurological8
- Ditunno JF Jr, Young W, Donovan WH, Creasey G. The international standards booklet for neurological and functional classification of spinal cord injury. (medscape.com)
- Six hundred sixty-one subjects enrolled in the Spinal Cord Injury Model Systems database, injured between 2000 and 2011, with initial neurological level of injury from T2-12. (nih.gov)
- Two hundred sixty-five subjects had second neurological exams and 400 subjects had Functional Independence Measure (FIM) scores ≥6 months after injury. (nih.gov)
- We mainly specialise in rehabilitation for those with spinal cord injuries, but also work with those who have other neurological conditions such as multiple sclerosis, Parkinson's Disease, stroke, and chronic pain, among many other conditions. (healthdirect.gov.au)
- One common reason behind lower urinary tract dysfunction is neurological damage secondary to spinal cord injury (SCI), spina bifida, or multiple sclerosis. (wellspect.com)
- The information on age, sex , occupation , cause, associated injuries , level of injury , neurological deficit, American spinal cord injury association ( ASIA ) score at presentation, complications and outcome were obtained from medical records department . (bvsalud.org)
- Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice. (umaryland.edu)
- Neurosurgeons at Barrow Neurological Institute have implanted the world's first scaffolding device into the spinal cord of a patient. (dignityhealth.org)
Paraplegia3
- The research was supported by the National Institutes of Health, the Veterans Administration, the Canadian Spinal Research Organization, and the Swiss Institute for Research into Paraplegia. (news-medical.net)
- Individuals aged 60 years at the time of injury have a life expectancy of approximately 7.7 years (patients with high tetraplegia), 9.9 years (patients with low tetraplegia), and 12.8 years (patients with paraplegia). (onteenstoday.com)
- Descriptive analysis was performed us- injuries leading to paraplegia and quadriple- ing SPSS software, version 10.0 for Win- gia. (who.int)
Patients25
- Spinal immobilization in patients with penetrating trauma is not recommended. (medscape.com)
- Because dopamine affects movement in many different animals, including humans, our studies may help to identify treatments for Parkinsons patients and those with spinal cord injury, said Mesce. (sci-info-pages.com)
- As with all trauma patients, initial clinical evaluation of a patient with suspected spinal cord injury (SCI) begins with a primary survey. (medscape.com)
- In all patients with spinal cord injury and hypotension, a diligent search for sources of hemorrhage must be made before hypotension is attributed to neurogenic shock. (medscape.com)
- While the target population is 17,000 patients, the foreseeable implications of an intraoperative blood flow monitor that could extend beyond SCI and may be used for other traumatic injury procedures. (jhu.edu)
- This is an exciting discovery with tremendous potential for the future treatment of spinal injury patients. (abdn.ac.uk)
- Eight to 10 patients with complete, grade A spinal cord injuries will be given single injections of oligodendrocyte progenitor cells derived from human embryonic stem cells. (medpagetoday.com)
- To qualify for inclusion, patients must have a contusional injury to the thoracic spine with complete loss of locomotor and sensory activity below the injury site. (medpagetoday.com)
- After an injury to the spinal cord, patients often remain paralyzed because damaged nerve tracts do not regrow due to the formation of scar tissue. (phys.org)
- Researchers are cautiously excited about these results which could potentially have a future role in the treatment of human patients with similar spinal injuries. (sci-info-pages.com)
- The device retrains patients with spinal cord injury to sit more stably and gain an expanded active sitting workspace. (techbriefs.com)
- Patients of Dr. Cronen can rest assured that their spinal health is in good hands. (floridamedicalclinic.com)
- Pre-treatment with cAMP could be a practical approach for treating patients with established, chronic spinal cord injuries, a possibility that is the subject of current study by the UCSD group. (news-medical.net)
- With these mattresses, spinal cord injury patients can get prevention of pressure sores and reduce the development of existing ulcers. (bedroom-furniture-collection.com)
- Christopher Reeve's death this past October from cardiac complications after infection resulting from pressure ulcers is a reminder that patients with spinal cord injury (SCI) are more than their motility impairments. (psychiatrictimes.com)
- According to the Annual Statistical Report of the National Spinal Cord Injury Statistical Center (NSCISC), published last June, of 3312 patients for whom the cause of death was known, nearly 22% died of respiratory system diseases, 9% of infective and parasitic diseases, 8% of hypertensive and ischemic heart diseases, and 13% of other heart disease. (psychiatrictimes.com)
- However, studies have shown that patients who continue to be physically active after suffering a spinal cord injury have a higher quality of life than those who do not. (thenewgait.com)
- To identify the complications and causes of death in traumatic spinal cord injury patients . (bvsalud.org)
- A 4-year retrospective review of all traumatic spinal cord injured patients treated at Benue State University Teaching Hospital Makurdi was conducted. (bvsalud.org)
- Recent large-scale longitudinal population -based studies indicate that patients with isolated SCI (without concurrent brain injury ) are at a high risk of dementia associated with substantial cognitive impairments . (bvsalud.org)
- Trauma patients who were hospi- the summer (23 August-21 September) talized for more than 24 hours and had and on Tuesdays with 12 (24.0%) cases sustained injuries within 7 days prior to ad- occurring on this day. (who.int)
- Concerning the outcome, 56% and 6.9% of patients with and without life-threatening injuries respectively, died. (who.int)
- Facilities of the highest quality should be available for patients with polytrauma, especially those with life-threatening injuries. (who.int)
- A new treatment using electrical currents to stimulate the spinal cord helped patients with limited ability to use their arms and hands. (medlineplus.gov)
- Inclusion criteria: The inclusion criteria were spinal cord injury patients with an outpatient appointment at the clinic with pressure ulcers stage II, III and IV (Black et al. (who.int)
Trauma8
- Trauma is the most common cause of spinal cord injury. (medicinenet.com)
- During 1994-1995 in Louisiana, five cases of central nervous system trauma associated with riding bulls in rodeo events were identified through the Louisiana Central Nervous System Injury Registry, a statewide, population-based surveillance system addressing brain and spinal cord injury incidence, etiology, and outcome. (cdc.gov)
- Spinal cord injury (SCI) is a devastating nerve injury caused by severe trauma to the spinal cord, leading to temporary or permanent somatosensory, and motor dysfunction ( Tohda and Kuboyama, 2011 ). (frontiersin.org)
- Trauma is a serious injury or shock to the body. (upstate.edu)
- Available at: https://www.merckmanuals.com/professional/injuries-poisoning/approach-to-the-trauma-patient/approach-to-the-trauma-patient. (upstate.edu)
- Injury (trauma) is the leading cause of death for all age groups under the age of 44. (medindia.net)
- Around one million people visit A&E departments every year with a form of brain trauma and road incidents account for 40-50% of all brain injuries. (hastingsdirect.com)
- The cervical collar can be discontinued without additional radiographic imaging in an awake, asymptomatic adult trauma patient with (1) a normal neurologic exam, (2) no high-risk injury mechanism, (3) free range of cervical motion, and (4) no neck tenderness. (medscape.com)
Thoracic6
- Ability to walk at 1 year was associated with low thoracic injury, higher initial LEMS, incomplete injury and increase in AIS grade. (nih.gov)
- If the force/pressure is too great, you get a herniation.We tend to see more cervical and lumbar injuries in a car accident and other personal injury cases, because those areas of the spine are way more mobile, whereas the thoracic area is really held tight by the rib cage. (neufeldlawfirm.com)
- Methods: Young adult male C57BL/6 mice were subjected to moderate/severe thoracic spinal cord contusion. (umaryland.edu)
- [7] [8] In humans, the red nucleus also has limited control over hands , as the rubrospinal tract is more involved in large muscle movement such as that for the arms (but not for the legs, as the tract terminates in the superior thoracic region of the spinal cord). (wikipedia.org)
- Increased a vdo to values typically greater than mm hg, heart rate is achieved by leaving the patient to subsequent fusion of the subjective response of arterial cannulation, the reported complication rate than adults to make a significant underlying cardiopulmonary or liver injury, thoracic aorta can cause a reaction occurs. (aaan.org)
- For more information, please go to C1 (Atlas) Fractures , C2 (Axis) Fractures , Lower Cervical Spine Fractures and Dislocations , Thoracic Spine Fractures and Dislocations , Lumbar Spine Fractures and Dislocations , and Spinal Cord Injuries . (medscape.com)
Contusion2
- He sustained a brain stem contusion and an incomplete C2 spinal cord injury and was unconscious for 16 days. (cdc.gov)
- In addition, contusion of spinal segments elicits distinct disabilities. (frontiersin.org)
Types of Spinal Cord Inj1
- There are two main types of spinal cord injuries - complete and incomplete. (cantorinjurylaw.com)
Researchers14
- A discovery by researchers at University of Minnesota may provide new insights into how the spinal cord controls walking, and this may pave the way for developing treatments for diseases of the central nervous like Parkinson's disease and spinal cord injuries. (sci-info-pages.com)
- The researchers chose to study a simpler model of locomotion in the medicinal leech, and this uncovered the residing spots of these unit burst generators and it also showed that each nerve cord segment has a complete generator. (sci-info-pages.com)
- To this end, researchers at University of California, San Diego School of Medicine and University of British Columbia (UBC) have now determined that, in mice, age diminishes ability to regenerate axons, the brain's communication wires in the spinal cord. (ucsd.edu)
- The researchers found that, as in young mice, Pten deletion in neurons of older mice elicited the types of post-injury cellular responses that often indicate increased regeneration. (ucsd.edu)
- In the study, published in The Journal of Neuroscience , the researchers modelled human spinal cord injury in rat nerve cells in a cell-culture dish. (abdn.ac.uk)
- In another first, not only did Epac2 stimulate growth, the researchers also found that it changed the internal environment at the injury site, making it more amenable to nerve regrowth and healing. (abdn.ac.uk)
- In recent years, researchers have made measurable progress, using animal models, to promote tissue regeneration in spinal cord injuries (SCI) through implanted neural stem cells or grafts. (sci-info-pages.com)
- Researchers at the Case Western Medical School and the Cleveland Clinic have developed a technique that regenerates nerve cells in rats, permitting them to urinate normally after severe spinal cord injury. (sci-info-pages.com)
- A one-time injection immediately after spinal cord injury that can limit pain for an extended period of time has come from a collaborative research led by researchers at Cleveland Clinic. (medindia.net)
- The researchers discovered, through testing in an animal model, that an injection of fibronectin into the spinal cord activates specific signaling pathways and results in pain-curbing effects. (medindia.net)
- Researchers found that fibronectin reversed spinal cord injury-induced decreases in serotonin, a neurotransmitter that plays an important role in pain perception. (medindia.net)
- But, researchers are actively seeking ways to stimulate spinal cord regeneration. (ahealthyme.com)
- Using a combination of therapies and cell grafts, a team of University of California, San Diego (UCSD) School of Medicine researchers has promoted significant regeneration of nerve cells in rats with spinal cord injury. (news-medical.net)
- Axon regeneration is one of the many challenges confronting spinal cord researchers. (news-medical.net)
Catastrophic16
- Re-issuance of the statement by the NATA comes in the wake of at least two deaths of high school football players from catastrophic cervical spine injuries in 2013. (momsteam.com)
- By stiffening the rules against dangerous play in ice hockey and giving referees less discretion in calling penalties, the Minnesota State High School League has taken an important first step to reduce the number of catastrophic injuries in the sport. (momsteam.com)
- Longtime Minnesota ice hockey coach Hal Tearse talks about how the catastrophic injury suffered by high school hockey player Jack "Jabs" Jablonski and suggests ways to make the sport safer. (momsteam.com)
- What is a Catastrophic Injury? (bradmclelland.com)
- A catastrophic injury is an injury so severe that it results in long-term or permanent effects that can impact your functional abilities. (bradmclelland.com)
- Catastrophic injuries are painful and expensive, and cases should be settled efficiently so you can move on. (bradmclelland.com)
- What Makes an Injury Catastrophic? (griffindurham.com)
- An injury is classified as catastrophic when it leaves a victim with long-term consequences and life-changing impacts. (griffindurham.com)
- Catastrophic injuries also include serious burns, injuries involving the lungs and heart, and certain types of birth injuries. (griffindurham.com)
- In other words, catastrophic injuries. (griffindurham.com)
- Federal law defines "catastrophic injury" as an injury with direct and proximate consequences that permanently prevent an individual from performing any gainful work. (griffindurham.com)
- In other words, a catastrophic injury is so serious that it leaves the victim with permanent damage. (griffindurham.com)
- Spinal cord injuries are some of the most catastrophic an individual can sustain. (cantorinjurylaw.com)
- Recovering after a catastrophic injury requires the help of several professionals. (neighborgoods.net)
- Catastrophic injuries can leave someone needing support and help he or she didn't need before an accident. (neighborgoods.net)
- Catastrophic injuries and life-altering disabilities can hurt an individual's mental health. (neighborgoods.net)
SCIs3
- In 1987, the Council of State and Territorial Epidemiologists (CSTE) recommended designating traumatic spinal cord injuries (SCIs) as the first injury condition reportable to state health agencies and to CDC. (cdc.gov)
- Editorial Note: CSTE's recommendation to designate SCIs as reportable was based on the magnitude of the morbidity and mortality due to traumatic SCIs, the cost associated with these injuries, and the potential for their prevention. (cdc.gov)
- Spinal cord injuries (SCIs) can cause devastating damage including loss of mobility and sensation. (techbriefs.com)
Lesions2
- Guidelines related to spinal cord injuries treatments are focused on avoidance of secondary injury from compressive lesions and hemodynamic instability. (medscape.com)
- AFM is an illness that's characterized by the sudden onset of flaccid weakness in one or more extremities and also by distinct longitudinal gray matter lesions in the spinal cord. (cdc.gov)
Live with spinal cord inj2
- More than 450,000 people live with spinal cord injuries in the United States, and 7,800 new cases are diagnosed every year. (bradmclelland.com)
- More than 250,000 Americans live with spinal cord injuries. (medlineplus.gov)
Symptoms of a spinal cord i2
- So, If you are wondering if your back pain is a spinal cord injury, read on to recognise the signs and symptoms of a spinal cord injury. (indiatimes.com)
- It's important to understand the symptoms of a spinal cord injury so you can seek treatment as soon as you notice them. (bradmclelland.com)
International Spinal Research Trust3
- This research was funded, in part, by the National Institutes of Health (grant R01NS054734), California Institute for Regenerative Medicine (grant RB3-02143), Canadian Institutes for Health Research, Wings for Life Foundation, International Spinal Research Trust, Craig H. Neilsen Foundation, and John and Penny Ryan British Columbia Leadership Chair in Spinal Cord Injury Research. (ucsd.edu)
- Mark Bacon, Executive and Scientific Director from International Spinal Research Trust who partly funded the research, added: "Repairing the damaged spinal cord remains one of the greatest challenges in medicine. (abdn.ac.uk)
- This work was supported by the International Spinal Research Trust, Scottish Rugby Union, The RS Macdonald Charitable Trust, Mr Graham Dixon & Mrs Pam Dixon, and Mr Willie Watt. (abdn.ac.uk)
Persons with spinal cord i4
- New results show promising findings on the use of an immune-stimulating vaccine (Uro-Vaxom®) for prophylactic therapy of UTIs in 136 persons with spinal cord injury. (wellspect.com)
- Contextualizing the lived experience of quality of life for persons with spinal cord injury: A mixed-methods application of the response shift model. (wellspect.com)
- Observational survey of 40 persons with spinal cord injury aimed at understanding individuals' quality of life (QOL) definitions, appraisals, and adaptations. (wellspect.com)
- Observational retrospective study of healthcare use during the first year after injury among 591 persons with spinal cord injury. (wellspect.com)
Individuals with spinal cord i2
- Everyday nutrition for individuals with spinal cord injury. (naric.com)
- Observational survey of health problems and functional goals among 203 community-dwelling individuals with spinal cord injury. (wellspect.com)
Chronic spinal cord i2
- Management of chronic spinal cord injury. (upstate.edu)
- Available at: https://www.dynamed.com/management/management-of-chronic-spinal-cord-injury. (upstate.edu)
Treatments2
- What Are the Treatments for Spinal Cord Injury (SCI)? (medlineplus.gov)
- The treatments and recovery methods the award aims to develop are to be implemented within days of injury, ultimately improving long-term outcomes. (photonics.com)
Incidence3
- To provide recent estimates of the incidence of traumatic spinal cord injury (SCI) in adults living in Ontario. (nih.gov)
- Incidence was estimated for the fiscal years 2003/04-2006/07, and examined by age, gender, mechanism and seasonality of injury, the level of injury, the presence of comorbidity and in-hospital mortality. (nih.gov)
- According to the World Health Organization [1] Spinal cord injury - WHO - https://www.who.int/news-room/fact-sheets/detail/spinal-cord-injury , the annual global incidence of spinal cord injury is 40 to 80 cases per million and this number is increasing every year. (bedroom-furniture-collection.com)
Bladder6
- Spinal cord injuries disrupt signalling from the brain leading to loss of limb, locomotion, sexual and bladder function, usually irreversible in humans. (wingsforlife.com)
- According to scientists Yu-Shang Lee and Jerry Silver, their technique raises hope that humans with such injuries may also be able to restore bladder and other functions. (sci-info-pages.com)
- A lower injury, in the lumbar vertebrae, may affect nerve and muscle control to the bladder, bowel, and legs, and sexual function. (ahealthyme.com)
- Bladder and urological complications are common and experienced by many people after spinal cord injury. (wellspect.com)
- Evaluation of the chronic effects of spinal cord injury (SCI) has long focused on sensorimotor deficits, neuropathic pain , bladder /bowel dysfunction, loss of sexual function, and emotional distress . (bvsalud.org)
- Things like MS, Parkinson's Disease, or spinal cord injuries can all lead to bladder leaks. (nafc.org)
Rats with spinal injury1
- Our research found that by targeting Epac2, we could potentially improve the mobility of rats with spinal injury. (abdn.ac.uk)
Damage to the spinal cord2
- The extent of the damage to the spinal cord determines whether the injury is complete or incomplete. (ahealthyme.com)
- MRIs (Magnetic Resonance Imaging) have revolutionized SCI diagnosis and treatment, because they allow PM&R physicians to visualize the damage to the spinal cord and can help them diagnose new symptoms that arise. (optimumhealthcare.org)
Regeneration1
- Deletion of the Pten gene promotes axon regeneration in young but not old mice after spinal cord injury. (ucsd.edu)
Treatment18
- The axial skeleton should be examined to identify and provide initial treatment of potentially unstable spinal fractures from both a mechanical and a neurologic basis. (medscape.com)
- Spinal Cord Injury (SCI) Medicine focuses on the prevention, diagnosis, treatment, and management of traumatic spinal cord injury and non-traumatic etiologies of spinal cord dysfunction by working in an interspecialty manner. (nrmp.org)
- it can carry treatment molecules to a specific site and then slowly release them, and it can also provide a scaffold to physically support injured nerve processes across an injury site. (abdn.ac.uk)
- The use of self-assembling hydrogel technology in spinal cord injury is relatively new and if it were to be used by neurosurgeons, could provide a more precise and less intrusive treatment than traditional invasive surgery. (abdn.ac.uk)
- Fund Phase 0, I, or II clinical trialswith the potential to have a major impact on treatment or management of spinal cord injury (SCI) and its consequences. (uoguelph.ca)
- A recent study has revealed new findings about nerve cell development that could help to facilitate future treatment options for spinal cord injuries. (sci-info-pages.com)
- The next stage of the study is to test the delayed fibronectin treatment on the inhibition of chronic pain after spinal cord injury, which is more clinically relevant. (medindia.net)
- Deciding which spinal treatment is best for your condition can be an overwhelming experience. (floridamedicalclinic.com)
- Seek medical treatment immediately after an accident to possibly help minimize the damage sustained to your spinal cord. (cantorinjurylaw.com)
- PM&R physicians have been pioneers in the treatment and management of spinal cord injuries. (optimumhealthcare.org)
- Typically, the physiatrist is brought in within 24-48 hours after the injury to coordinate any non-surgical treatment and continues as the patient's primary attending physician. (optimumhealthcare.org)
- Results: Flow cytometry analysis demonstrated that PLX5622 pre-treatment significantly reduced the number of microglia, as well as infiltrating monocytes and neutrophils, and decreased reactive oxygen species production in these cells from injured spinal cord at 2-days post-injury. (umaryland.edu)
- Post-injury PLX5622 treatment reduced both CD45int microglia and CD45hi myeloid counts at 7-days. (umaryland.edu)
- Following six weeks of PLX5622 treatment, there were substantial changes in the spinal cord and brain transcriptomes, including those involved in neuroinflammation. (umaryland.edu)
- Specifically, Spinalis whose main goal is to support research and treatment of spinal cord injuries. (bikerumor.com)
- Extreme traumatic brain injury (TBI) may demand specialized treatment and perhaps life-saving surgeries. (odglawgroup.com)
- This is a major milestone for spinal cord injury treatment and we are elated to be the first hospital in the world to perform this innovative surgery and to be part of the clinical trial," says Nicholas Theodore, MD, Chief of Spinal Surgery at Barrow and principal investigator of the study. (dignityhealth.org)
- I'm excited to be the first patient in this research study that may one day become the standard of spinal cord injury treatment. (dignityhealth.org)
Fractures3
- Spinal cord injuries usually begin with a blow that fractures (breaks) or dislocates your vertebrae, the bone disks that make up your spine. (medlineplus.gov)
- He sustained an incomplete T10-T11 spinal cord injury, multiple rib fractures, a tension pneumothorax, and a splenic injury. (cdc.gov)
- He sustained a brain injury and multiple nasal fractures and was unconscious for 5 days. (cdc.gov)
20181
- la muestra estuvo conformada por 2.460 publicaciones, Enfermagem Magalhães Barata, Programa de con predominio de artículos originales, en inglés, de los años 2018 a 2020. (bvsalud.org)
Accidents9
- A spinal cord injury can be caused due to osteoporosis, arthritis, diving, sports or accidents. (indiatimes.com)
- Spine injuries are some of the most common injuries we see in motorcycle accidents, car accidents, bicycle accidents, and slip and falls. (neufeldlawfirm.com)
- Common accidents that cause these injuries include motor vehicle accidents involving cars, buses, motorcycles, and trucks. (bradmclelland.com)
- Numerous severe accidents can result in spinal cord injuries. (cantorinjurylaw.com)
- Texas residents are sometimes involved in motor vehicle accidents or mishaps in the workplace that result in traumatic injury. (woodlandsinjurylawyer.com)
- Road accidents account for the largest cause of spinal cord injuries on a global scale. (hastingsdirect.com)
- Sports injuries, automobile crashes, assaults, and slip and fall accidents are all common causes of this life-altering injury, among others. (odglawgroup.com)
- Bicycle accidents, SUV and pickup truck collisions, blasts and explosions, and sexual and physical attacks are all potential causes of traumatic brain injury. (odglawgroup.com)
- Pedestrian injuries and deaths from accidents in California are statistically more likely than in any other state in the nation. (autoaccident.com)
Level of the spinal2
- The degree of respiratory dysfunction is ultimately dependent on preexisting pulmonary comorbidity, the level of the spinal cord injury, and any associated chest wall or lung injury. (medscape.com)
- Secondary health problems depend on the level of the spinal cord that sustained the injury and the degree of injury. (psychiatrictimes.com)
Vertebrae5
- Instead, they cause damage when pieces of vertebrae tear into cord tissue or press down on the nerve parts that carry signals. (medlineplus.gov)
- When vertebrae are broken or dislocated, the result can cause traumatic injury to the spinal cord. (medicinenet.com)
- A 28-year-old man with 15 years' riding experience was thrown to the ground while riding a bull and suffered a fracture of the fifth and sixth cervical vertebrae and an incomplete * spinal cord injury. (cdc.gov)
- For example, an injury to the neck, the first and second vertebrae in the spinal column (C1, C2), or the mid-cervical vertebrae (C3, C4, and C5) affects the respiratory muscles and the ability to breathe. (ahealthyme.com)
- If damage is done to the vertebrae, discs, or ligaments of the spinal column, it would result in a spinal cord injury. (cantorinjurylaw.com)
20163
- When my Dad was injured in 2016, SCIO was instrumental in helping him and our family navigate the endless challenges that a spinal cord injury can present. (sciontario.org)
- The league announced in January that, according to its preliminary injury data, concussions suffered by players increased by nearly 16 percent last season over the 2016 season. (washingtonpost.com)
- Data collection occurred from January to June 2016, through interviews with 23 people with spinal cord injury, identified from the Family Health Strategy teams and from the Support to Adapted Sports Association and analyzed by thematic content. (bvsalud.org)
Secondary3
- Additionally, SCI also can be classified into primary injury and secondary injury, based on the pathological nature of the damage. (frontiersin.org)
- As a result of spinal cord injury, secondary diseases can develop that can even be life-threatening. (bedroom-furniture-collection.com)
- When neural pathways become damaged or destroyed by a spinal cord injury, it can result in loss of sensation, immobility, and other secondary effects . (flintrehab.com)
Brain30
- Mayo Clinic's spinal cord injury team is led by doctors trained in brain and nervous system disorders (neurologists), brain and nervous system surgery (neurosurgeons), nerve and muscle physiology and rehabilitation (physiatrists), and bone and muscle surgery (orthopedic surgeons). (mayoclinic.org)
- In mammals, axons in the brain and spinal cord are limited in their ability to regenerate after injury. (ucsd.edu)
- The spinal cord is an important component of our central nervous system: it connects the brain with the rest of the body and plays a crucial part in coordinating our sensations with our actions. (phys.org)
- Spinal cord injuries cause myelopathy or damage to white matter or myelinated fiber tracts that carry signals to and from the brain. (phys.org)
- Recent advances in traumatic brain injury. (upstate.edu)
- Fibronectin - a protein that exists naturally in humans - supports the survival, growth and communication of neurons in the brain and spinal cord. (medindia.net)
- Head injury or traumatic brain injury is a leading cause of disability among children and young adults that leads to varying degrees of physical and mental stability. (medindia.net)
- Examples include burns that require extensive surgeries, amputations that force you to quit your job if you can no longer perform your daily tasks, and brain injuries that affect your memory, communicative skills, and more. (bradmclelland.com)
- These types of injuries, which often involve damage to the brain or. (griffindurham.com)
- The spinal cord uses neural pathways to communicate with the brain and muscles. (flintrehab.com)
- Neuroinflammation in the injured spinal cord and brain was assessed using flow cytometry and NanoString technology. (umaryland.edu)
- Conclusion: These findings indicate that pharmacological microglia-deletion reduces neuroinflammation in the injured spinal cord and brain, improving recovery of cognition, depressive-like behavior, and motor function. (umaryland.edu)
- Dementia, Depression, and Associated Brain Inflammatory Mechanisms after Spinal Cord Injury. (bvsalud.org)
- In addition, we outline the existing and developing therapeutic options aimed at reducing SCI-induced brain neuroinflammation and post- injury cognitive and emotional impairments. (bvsalud.org)
- For example, someone who has a brain injury may have trouble remembering things. (neighborgoods.net)
- Traumatic brain injuries, commonly known as TBIs, may be devastating in these times of hardship. (odglawgroup.com)
- Injury deaths from traumatic brain injury (TBI) account for over 30% of fatalities each year, including over 2.5 million emergency room visits. (odglawgroup.com)
- Other people's carelessness or malicious intent that results in a major traumatic brain injury in Los Angeles (TBI) may entitle you or a loved one to compensation under the law. (odglawgroup.com)
- If you have suffered a traumatic brain injury, you will need the assistance of an expert traumatic brain injury lawyer in Los Angeles from the ODG Law Group to prove your TBI claim successfully. (odglawgroup.com)
- Traumatic brain injury (TBI) is brain damage that occurs unexpectedly due to a blow to the head or a hit to the head. (odglawgroup.com)
- From mild interruptions to serious long-term brain injury, there is a wide spectrum of possibilities. (odglawgroup.com)
- Those who have experienced a severe to life-threatening traumatic brain injury (TBI) will need rehabilitation to recover and re-learn abilities. (odglawgroup.com)
- According to the Brain Injury Association of America (BIAA) report, almost 1.5 million individuals in the United States suffer traumatic brain injury (TBI) each year. (odglawgroup.com)
- Furthermore, almost 50,000 individuals succumb to traumatic brain injuries each year in the United States. (odglawgroup.com)
- Approximately 5.3 million individuals are now living with disabilities as a result of traumatic brain injury. (odglawgroup.com)
- When you encounter someone who has had a traumatic brain injury, you may assume that they can speak, walk, and seem well. (odglawgroup.com)
- Anyone may be held liable if they fail to take reasonable precautions to warn others of a danger that results in traumatic brain injury. (odglawgroup.com)
- These defects may either exacerbate or even induce a traumatic brain injury. (odglawgroup.com)
- Lindsay, [ 985 ] a mother with physical disabilities and a traumatic brain injury, affirms the significance of services: "Given my lack of trust in 'the system' and sparse community support resources, I cannot be both a full-time parent and a good parent. (ncd.gov)
- Our current neuroscience clinical trials focus on research for Alzheimer's and dementia, stroke, Parkinson's disease, spinal cord injury and traumatic brain injury. (froedtert.com)
Cervical spinal2
- Is it even conceivable to continue engaging in physically demanding activities after suffering serious damage to the cervical spinal cord, such as a C6 spinal cord injury, for example? (thenewgait.com)
- Open or percutaneous tracheostomy can be performed early after anterior cervical spinal stabilization without increasing the risk of infection or other wound complications. (medscape.com)
Surgery10
- Rod Quinn and Dr James St John from Griffith University discuss the present and future for those suffering from spinal cord injury, in the immediate wake of Poland's successful surgery resulting in a paralysed man learning to walk again. (abc.net.au)
- Some injuries may require surgery. (upstate.edu)
- Dr. Cronen is a leader in the Southeast United States for spinal deformities and reconstructive surgery. (floridamedicalclinic.com)
- Surgery is sometimes needed to assess the injured spinal cord, stabilize fractured backbones, release the pressure from the injured area, and to manage any other injuries that may have been a result of the accident. (ahealthyme.com)
- It's used for people with limited movement, or after surgery due to injury, disease (like cancer), osteoporosis, or any other reason that requires immobilization of your back. (bedroom-furniture-collection.com)
- injury and surgery are causes of vascular injury, and prolonged bed rest can cause stasis. (cdc.gov)
- Back Spinal Surgery - How to prevent? (singhealth.com.sg)
- Most spinal surgery is done under general anaesthesia. (singhealth.com.sg)
- Performed last month, the surgery involves inserting a scaffolding implant to act as a bridge across the gap of the injured section of the cord in an attempt to help the spinal cord heal. (dignityhealth.org)
- A section of his spinal cord was injured and he was airlifted to Barrow which is located at Dignity Health St. Joseph's Hospital and Medical Center, where he underwent emergency surgery by Dr. Theodore that evening. (dignityhealth.org)
Epidemiology2
- Epidemiology of traumatic spinal cord injury. (medscape.com)
- Div of Injury Epidemiology and Control, Center for Environmental Health and Injury Control, CDC. (cdc.gov)
Incomplete spinal6
- Those with incomplete spinal cord injuries would still be able to function below the affected area and experience sensations as well. (cantorinjurylaw.com)
- Is Incomplete Spinal Cord Injury Recovery Time Limited? (flintrehab.com)
- However, many individuals with an incomplete spinal cord injury experience the largest spike in recovery during the first 3-6 months post-injury. (flintrehab.com)
- However, incomplete spinal cord injury recovery time is not limited to that first year of heightened plasticity. (flintrehab.com)
- To continuously activate neuroplasticity and optimize your incomplete spinal cord injury recovery time, it's important to practice high repetition of exercises daily. (flintrehab.com)
- However, in addition to exercise, there are other factors that can hinder or promote healing after an incomplete spinal cord injury and affect recovery time. (flintrehab.com)
People27
- Mayo Clinic doctors and staff have helped thousands of people recover from spinal cord injuries and diseases. (mayoclinic.org)
- Every year, more than 73,000 people receive care for spinal cord injuries and diseases from doctors and other health professionals at Mayo Clinic. (mayoclinic.org)
- In other words, middle-aged adults, the peak age group for people living with a paralyzing spinal cord injury today, already have a significantly reduced ability to regenerate, as compared to young adults. (ucsd.edu)
- The foundation named for the Augusta native, hockey star and advocate for people with spinal cord injuries is ending its run by making two donations totaling $4 million. (centralmaine.com)
- A support group that "Taps" into real life triumphs, challenges and opportunities for people with spinal cord injury. (wellspan.org)
- Join us for an opportunity to share your story, receive encouragement and support, and learn adaptive techniques from other people with spinal cord injuries. (wellspan.org)
- In this article, we will talk about what mattress is best for people with spinal cord injuries, as well as 3 mattresses that are worth looking into if you suffer from this condition. (bedroom-furniture-collection.com)
- It's very important to provide the necessary comfort and back support to people with injury. (bedroom-furniture-collection.com)
- The first downside is that these mattresses can be expensive for some people because they are specialized and designed only for spinal cord injury. (bedroom-furniture-collection.com)
- These are just some of the wonderful people in our community who give to help people with spinal cord injury live a life with choice. (sciontario.org)
- Jude's beloved Grandpa Ron sustained a spinal cord injury and Jude was inspired by to hand make and sell decorations to raise money to help people with spinal cord injuries. (sciontario.org)
- Seeing the support and guidance SCIO offered to my friend and continues to provide people with spinal cord injuries and other physical disabilities inspired me to donate and to keep donating. (sciontario.org)
- and you can improve accessibility in Ontario and help us serve, support and advocate for and with people with spinal cord injury and other disabilities. (sciontario.org)
- Because of these injuries, many people who have survived a spinal cord injury may end up adopting a sedentary lifestyle, which can result in the development of other health concerns. (thenewgait.com)
- Between 8,000 and 10,000 people experience a spinal cord injury (SCI) each year , causing about 250,000 people today to be living with the condition. (optimumhealthcare.org)
- People experiencing a traumatic spinal cord injury face many life-changing consequences of their injury. (wellspect.com)
- Epidemiological data on self-reported problems and goals associated from people with spinal cord injury. (wellspect.com)
- Every year, around the world, between 250 000 and 500 000 people suffer a spinal cord injury (SCI). (who.int)
- People with a spinal cord injury are two to five times more likely to die prematurely than people without a spinal cord injury, with worse survival rates in low- and middle-income countries. (who.int)
- How long do people live after a spinal cord injury? (onteenstoday.com)
- Hodge reminds herself that some people just don't realize it's possible for women with spinal cord injuries (and other physical disabilities ) to get pregnant and give birth. (todaysparent.com)
- Yasaman Best, a Vancouver mom with a spinal cord injury who gave birth to her son, Alex, in June 2015, says she was shocked when a close friend told her she thought it was "unethical" for people who use wheelchairs to have babies. (todaysparent.com)
- People recovering from an injury need to push themselves to achieve better results in the recovery process, but only within reason. (neighborgoods.net)
- Some people hesitate to reach out and speak to a personal injury attorney because they have heard stories about how they will be on the hook for an outrageous hourly billable rate or hefty retainer fee. (autoaccident.com)
- The aim was to apprehend the (in) accessibility experiences of people with spinal cord injury. (bvsalud.org)
- Two categories emerged, which show that people with spinal cord injury face difficulties in conducting their daily activitieswith autonomy, insufficiency and/or deficiency in accessibility and family and social support. (bvsalud.org)
- The adequate implementation of public policies for inclusion and accessibility that are existing would facilitate and allow people with spinal cord injury to have greater socialization and participation in health-related activities and adapted sports. (bvsalud.org)
Nerve fibers2
- Rodent studies have indicated that the cells cause spinal nerve fibers to remyelinate after subacute injuries, restoring a measure of neuromotor and sensory function, said Thomas Okarma, Ph.D., M.D., Geron's president and CEO, at a press briefing. (medpagetoday.com)
- The therapeutic approach successfully stimulated new nerve fibers called axons to grow and extend well beyond the site of the injury into surrounding tissue, following surgically induced spinal cord damage. (news-medical.net)
Dysfunction1
- Science Alert: Neurogenic lower urinary tract dysfunction from 3 perspectives - spinal cord injury, spina bifida, and multiple sclerosis. (wellspect.com)
Neural5
- As the system delivers information, team members will simultaneously, and from the delivered information, be able to determine the optimal time to transplant neural stem cells and 3D scaffold - critical, time-sensitive assessments and implementations following spinal injury, when large swings in blood pressure are common. (photonics.com)
- meaning there are no existing neural pathways below the level of injury. (flintrehab.com)
- However, with an incomplete injury the spinal cord is only partially severed and there are spared neural pathways remaining. (flintrehab.com)
- The level of spinal cord injury (the lowest region where movement and sensation exist) determines which muscles and neural pathways are recoverable. (flintrehab.com)
- Background/Objective: In spinal cord injury (SCI), loss of central or peripheral neural control causes neurogenic bowel. (ewha.ac.kr)
Rehabilitation Medicine1
- Northwest Regional Spinal Cord Injury System University of Washington Rehabilitation Medicine, Box 356490 Seattle, WA 98195 800/366-5643. (naric.com)
Severe spinal1
- Shazier is rehabilitating a severe spinal cord injury suffered during a December game. (washingtonpost.com)
Cause spinal1
- Virtually any accident can cause spinal cord injuries depending on where an individual is struck and the force applied. (bradmclelland.com)
Neck2
- These typically affect the spinal cord in the neck area. (ahealthyme.com)
- After an injury, your head and neck will be immobilized to prevent movement. (ahealthyme.com)
Stimulation2
- Evaluate and compare the health benefits of an at home exercise program using functional electrical stimulation (FES) for lower extremity exercise with diet versus a diet alone group in adults with spinal cord injury. (clinicaltrials.gov)
- The additional technologies include an implantable mean arterial pressure sensor and a spinal cord stimulation and blood pressure regulation system. (photonics.com)
Functional recovery2
- Persons who are older at the time of injury have poorer functional recovery than younger persons. (nih.gov)
- Stabilizing hemodynamics within days of injury improves functional recovery. (photonics.com)
Mortality2
- Krause JS, Sternberg M, Lottes S, Maides J. Mortality after spinal cord injury: an 11-year prospective study. (medscape.com)
- Background Spinal cord injury is commonly associated with morbidity and mortality . (bvsalud.org)