Software: Sequential operating programs and data which instruct the functioning of a digital computer.Software Design: Specifications and instructions applied to the software.Software Validation: The act of testing the software for compliance with a standard.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Programming Languages: Specific languages used to prepare computer programs.Computer Graphics: The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Database Management Systems: Software designed to store, manipulate, manage, and control data for specific uses.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Microcomputers: Small computers using LSI (large-scale integration) microprocessor chips as the CPU (central processing unit) and semiconductor memories for compact, inexpensive storage of program instructions and data. They are smaller and less expensive than minicomputers and are usually built into a dedicated system where they are optimized for a particular application. "Microprocessor" may refer to just the CPU or the entire microcomputer.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Systems Integration: The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Computer Systems: Systems composed of a computer or computers, peripheral equipment, such as disks, printers, and terminals, and telecommunications capabilities.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Automatic Data Processing: Data processing largely performed by automatic means.Automation: Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)ComputersComputer Communication Networks: A system containing any combination of computers, computer terminals, printers, audio or visual display devices, or telephones interconnected by telecommunications equipment or cables: used to transmit or receive information. (Random House Unabridged Dictionary, 2d ed)Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Models, Statistical: Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.Radiology Information Systems: Information systems, usually computer-assisted, designed to store, manipulate, and retrieve information for planning, organizing, directing, and controlling administrative activities associated with the provision and utilization of radiology services and facilities.Workflow: Description of pattern of recurrent functions or procedures frequently found in organizational processes, such as notification, decision, and action.Data Interpretation, Statistical: Application of statistical procedures to analyze specific observed or assumed facts from a particular study.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Data Display: The visual display of data in a man-machine system. An example is when data is called from the computer and transmitted to a CATHODE RAY TUBE DISPLAY or LIQUID CRYSTAL display.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Image Interpretation, Computer-Assisted: Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Genome: The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.Pattern Recognition, Automated: In INFORMATION RETRIEVAL, machine-sensing or identification of visible patterns (shapes, forms, and configurations). (Harrod's Librarians' Glossary, 7th ed)Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Computer-Assisted Instruction: A self-learning technique, usually online, involving interaction of the student with programmed instructional materials.Automation, Laboratory: Controlled operations of analytic or diagnostic processes, or systems by mechanical or electronic devices.Hypermedia: Computerized compilations of information units (text, sound, graphics, and/or video) interconnected by logical nonlinear linkages that enable users to follow optimal paths through the material and also the systems used to create and display this information. (From Thesaurus of ERIC Descriptors, 1994)Radiographic Image Interpretation, Computer-Assisted: Computer systems or networks designed to provide radiographic interpretive information.Sequence Analysis, RNA: A multistage process that includes cloning, physical mapping, subcloning, sequencing, and information analysis of an RNA SEQUENCE.Artificial Intelligence: Theory and development of COMPUTER SYSTEMS which perform tasks that normally require human intelligence. Such tasks may include speech recognition, LEARNING; VISUAL PERCEPTION; MATHEMATICAL COMPUTING; reasoning, PROBLEM SOLVING, DECISION-MAKING, and translation of language.Computing Methodologies: Computer-assisted analysis and processing of problems in a particular area.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Diagnosis, Computer-Assisted: Application of computer programs designed to assist the physician in solving a diagnostic problem.Observer Variation: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).Computer-Aided Design: The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics.Documentation: Systematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature (From ALA Glossary of Library and Information Science, 1983). It often involves authenticating or validating information.Equipment Design: Methods of creating machines and devices.Speech Recognition Software: Software capable of recognizing dictation and transcribing the spoken words into written text.Medical Records Systems, Computerized: Computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record.Mass Spectrometry: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.High-Throughput Nucleotide Sequencing: Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.Online Systems: Systems where the input data enter the computer directly from the point of origin (usually a terminal or workstation) and/or in which output data are transmitted directly to that terminal point of origin. (Sippl, Computer Dictionary, 4th ed)Bayes Theorem: A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Information Systems: Integrated set of files, procedures, and equipment for the storage, manipulation, and retrieval of information.Databases, Nucleic Acid: Databases containing information about NUCLEIC ACIDS such as BASE SEQUENCE; SNPS; NUCLEIC ACID CONFORMATION; and other properties. Information about the DNA fragments kept in a GENE LIBRARY or GENOMIC LIBRARY is often maintained in DNA databases.Proteome: The protein complement of an organism coded for by its genome.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Quality Control: A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)Systems Biology: Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.Data Mining: Use of sophisticated analysis tools to sort through, organize, examine, and combine large sets of information.Phantoms, Imaging: Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)Hospital Information Systems: Integrated, computer-assisted systems designed to store, manipulate, and retrieve information concerned with the administrative and clinical aspects of providing medical services within the hospital.Computers, Handheld: A type of MICROCOMPUTER, sometimes called a personal digital assistant, that is very small and portable and fitting in a hand. They are convenient to use in clinical and other field situations for quick data management. They usually require docking with MICROCOMPUTERS for updates.Local Area Networks: Communications networks connecting various hardware devices together within or between buildings by means of a continuous cable or voice data telephone system.Databases as Topic: Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)Markov Chains: A stochastic process such that the conditional probability distribution for a state at any future instant, given the present state, is unaffected by any additional knowledge of the past history of the system.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Diagnostic Imaging: Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Cone-Beam Computed Tomography: Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.Signal Processing, Computer-Assisted: Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.Photography: Method of making images on a sensitized surface by exposure to light or other radiant energy.Word Processing: Text editing and storage functions using computer software.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Medical Informatics: The field of information science concerned with the analysis and dissemination of medical data through the application of computers to various aspects of health care and medicine.Surgery, Computer-Assisted: Surgical procedures conducted with the aid of computers. This is most frequently used in orthopedic and laparoscopic surgery for implant placement and instrument guidance. Image-guided surgery interactively combines prior CT scans or MRI images with real-time video.Image Enhancement: Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Likelihood Functions: Functions constructed from a statistical model and a set of observed data which give the probability of that data for various values of the unknown model parameters. Those parameter values that maximize the probability are the maximum likelihood estimates of the parameters.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Data Compression: Information application based on a variety of coding methods to minimize the amount of data to be stored, retrieved, or transmitted. Data compression can be applied to various forms of data, such as images and signals. It is used to reduce costs and increase efficiency in the maintenance of large volumes of data.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Models, Anatomic: Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study.Tandem Mass Spectrometry: A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.Radiographic Image Enhancement: Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.Artifacts: Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.Microscopy: The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Computer Storage Devices: Devices capable of receiving data, retaining data for an indefinite or finite period of time, and supplying data upon demand.Decision Making, Computer-Assisted: Use of an interactive computer system designed to assist the physician or other health professional in choosing between certain relationships or variables for the purpose of making a diagnostic or therapeutic decision.CD-ROM: An optical disk storage system for computers on which data can be read or from which data can be retrieved but not entered or modified. A CD-ROM unit is almost identical to the compact disk playback device for home use.Teleradiology: The electronic transmission of radiological images from one location to another for the purposes of interpretation and/or consultation. Users in different locations may simultaneously view images with greater access to secondary consultations and improved continuing education. (From American College of Radiology, ACR Standard for Teleradiology, 1994, p3)Monte Carlo Method: In statistics, a technique for numerically approximating the solution of a mathematical problem by studying the distribution of some random variable, often generated by a computer. The name alludes to the randomness characteristic of the games of chance played at the gambling casinos in Monte Carlo. (From Random House Unabridged Dictionary, 2d ed, 1993)Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Biochemical Processes: Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things.Molecular Sequence Annotation: The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.Anatomy, Cross-Sectional: Descriptive anatomy based on three-dimensional imaging (IMAGING, THREE-DIMENSIONAL) of the body, organs, and structures using a series of computer multiplane sections, displayed by transverse, coronal, and sagittal analyses. It is essential to accurate interpretation by the radiologist of such techniques as ultrasonic diagnosis, MAGNETIC RESONANCE IMAGING, and computed tomography (TOMOGRAPHY, X-RAY COMPUTED). (From Lane & Sharfaei, Modern Sectional Anatomy, 1992, Preface)Information Management: Management of the acquisition, organization, storage, retrieval, and dissemination of information. (From Thesaurus of ERIC Descriptors, 1994)Mathematical Computing: Computer-assisted interpretation and analysis of various mathematical functions related to a particular problem.Chromatography, Liquid: Chromatographic techniques in which the mobile phase is a liquid.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Geographic Information Systems: Computer systems capable of assembling, storing, manipulating, and displaying geographically referenced information, i.e. data identified according to their locations.

An effective approach for analyzing "prefinished" genomic sequence data. (1/21774)

Ongoing efforts to sequence the human genome are already generating large amounts of data, with substantial increases anticipated over the next few years. In most cases, a shotgun sequencing strategy is being used, which rapidly yields most of the primary sequence in incompletely assembled sequence contigs ("prefinished" sequence) and more slowly produces the final, completely assembled sequence ("finished" sequence). Thus, in general, prefinished sequence is produced in excess of finished sequence, and this trend is certain to continue and even accelerate over the next few years. Even at a prefinished stage, genomic sequence represents a rich source of important biological information that is of great interest to many investigators. However, analyzing such data is a challenging and daunting task, both because of its sheer volume and because it can change on a day-by-day basis. To facilitate the discovery and characterization of genes and other important elements within prefinished sequence, we have developed an analytical strategy and system that uses readily available software tools in new combinations. Implementation of this strategy for the analysis of prefinished sequence data from human chromosome 7 has demonstrated that this is a convenient, inexpensive, and extensible solution to the problem of analyzing the large amounts of preliminary data being produced by large-scale sequencing efforts. Our approach is accessible to any investigator who wishes to assimilate additional information about particular sequence data en route to developing richer annotations of a finished sequence.  (+info)

A computational screen for methylation guide snoRNAs in yeast. (2/21774)

Small nucleolar RNAs (snoRNAs) are required for ribose 2'-O-methylation of eukaryotic ribosomal RNA. Many of the genes for this snoRNA family have remained unidentified in Saccharomyces cerevisiae, despite the availability of a complete genome sequence. Probabilistic modeling methods akin to those used in speech recognition and computational linguistics were used to computationally screen the yeast genome and identify 22 methylation guide snoRNAs, snR50 to snR71. Gene disruptions and other experimental characterization confirmed their methylation guide function. In total, 51 of the 55 ribose methylated sites in yeast ribosomal RNA were assigned to 41 different guide snoRNAs.  (+info)

Randomly amplified polymorphic DNA analysis of clinical and environmental isolates of Vibrio vulnificus and other vibrio species. (3/21774)

Vibrio vulnificus is an estuarine bacterium that is capable of causing a rapidly fatal infection in humans. A randomly amplified polymorphic DNA (RAPD) PCR protocol was developed for use in detecting V. vulnificus, as well as other members of the genus Vibrio. The resulting RAPD profiles were analyzed by using RFLPScan software. This RAPD method clearly differentiated between members of the genus Vibrio and between isolates of V. vulnificus. Each V. vulnificus strain produced a unique band pattern, indicating that the members of this species are genetically quite heterogeneous. All of the vibrios were found to have amplification products whose sizes were within four common molecular weight ranges, while the V. vulnificus strains had an additional two molecular weight range bands in common. All of the V. vulnificus strains isolated from clinical specimens produced an additional band that was only occasionally found in environmental strains; this suggests that, as is the case with the Kanagawa hemolysin of Vibrio parahaemolyticus, the presence of this band may be correlated with the ability of a strain to produce an infection in humans. In addition, band pattern differences were observed between encapsulated and nonencapsulated isogenic morphotypes of the same strain of V. vulnificus.  (+info)

Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11. (4/21774)

In this study we used TEPITOPE, a new epitope prediction software, to identify sequence segments on the MAGE-3 protein with promiscuous binding to histocompatibility leukocyte antigen (HLA)-DR molecules. Synthetic peptides corresponding to the identified sequences were synthesized and used to propagate CD4(+) T cells from the blood of a healthy donor. CD4(+) T cells strongly recognized MAGE-3281-295 and, to a lesser extent, MAGE-3141-155 and MAGE-3146-160. Moreover, CD4(+) T cells proliferated in the presence of recombinant MAGE-3 after processing and presentation by autologous antigen presenting cells, demonstrating that the MAGE-3 epitopes recognized are naturally processed. CD4(+) T cells, mostly of the T helper 1 type, showed specific lytic activity against HLA-DR11/MAGE-3-positive melanoma cells. Cold target inhibition experiments demonstrated indeed that the CD4(+) T cells recognized MAGE-3281-295 in association with HLA-DR11 on melanoma cells. This is the first evidence that a tumor-specific shared antigen forms CD4(+) T cell epitopes. Furthermore, we validated the use of algorithms for the prediction of promiscuous CD4(+) T cell epitopes, thus opening the possibility of wide application to other tumor-associated antigens. These results have direct implications for cancer immunotherapy in the design of peptide-based vaccines with tumor-specific CD4(+) T cell epitopes.  (+info)

Imagene: an integrated computer environment for sequence annotation and analysis. (5/21774)

MOTIVATION: To be fully and efficiently exploited, data coming from sequencing projects together with specific sequence analysis tools need to be integrated within reliable data management systems. Systems designed to manage genome data and analysis tend to give a greater importance either to the data storage or to the methodological aspect, but lack a complete integration of both components. RESULTS: This paper presents a co-operative computer environment (called Imagenetrade mark) dedicated to genomic sequence analysis and annotation. Imagene has been developed by using an object-based model. Thanks to this representation, the user can directly manipulate familiar data objects through icons or lists. Imagene also incorporates a solving engine in order to manage analysis tasks. A global task is solved by successive divisions into smaller sub-tasks. During program execution, these sub-tasks are graphically displayed to the user and may be further re-started at any point after task completion. In this sense, Imagene is more transparent to the user than a traditional menu-driven package. Imagene also provides a user interface to display, on the same screen, the results produced by several tasks, together with the capability to annotate these results easily. In its current form, Imagene has been designed particularly for use in microbial sequencing projects. AVAILABILITY: Imagene best runs on SGI (Irix 6.3 or higher) workstations. It is distributed free of charge on a CD-ROM, but requires some Ilog licensed software to run. Some modules also require separate license agreements. Please contact the authors for specific academic conditions and other Unix platforms. CONTACT: imagene home page: http://wwwabi.snv.jussieu.fr/imagene  (+info)

Stem Trace: an interactive visual tool for comparative RNA structure analysis. (6/21774)

MOTIVATION: Stem Trace is one of the latest tools available in STRUCTURELAB, an RNA structure analysis computer workbench. The paradigm used in STRUCTURELAB views RNA structure determination as a problem of dealing with a database of a large number of computationally generated structures. Stem Trace provides the capability to analyze this data set in a novel, visually driven, interactive and exploratory way. In addition to providing graphs at a high level of ion, it is also connected with complementary visualization tools which provide orthogonal views of the same data, as well as drawing of structures represented by a stem trace. Thus, on top of being an analysis tool, Stem Trace is a graphical user interface to an RNA structural information database. RESULTS: We illustrate Stem Trace's capabilities with several examples of the analysis of RNA folding data performed on 24 strains of HIV-1, HIV-2 and SIV sequences around the HIV dimerization region. This dimer linkage site has been found to play a role in encapsidation, reverse transcription, recombination, and inhibition of translation. Our examples show how Stem Trace elucidates preservation of structures in this region across the various strains of HIV. AVAILABILITY: The program can be made available upon request. It runs on SUN, SGI and DEC (Compaq) Unix workstations.  (+info)

Bayesian inference on biopolymer models. (7/21774)

MOTIVATION: Most existing bioinformatics methods are limited to making point estimates of one variable, e.g. the optimal alignment, with fixed input values for all other variables, e.g. gap penalties and scoring matrices. While the requirement to specify parameters remains one of the more vexing issues in bioinformatics, it is a reflection of a larger issue: the need to broaden the view on statistical inference in bioinformatics. RESULTS: The assignment of probabilities for all possible values of all unknown variables in a problem in the form of a posterior distribution is the goal of Bayesian inference. Here we show how this goal can be achieved for most bioinformatics methods that use dynamic programming. Specifically, a tutorial style description of a Bayesian inference procedure for segmentation of a sequence based on the heterogeneity in its composition is given. In addition, full Bayesian inference algorithms for sequence alignment are described. AVAILABILITY: Software and a set of transparencies for a tutorial describing these ideas are available at http://www.wadsworth.org/res&res/bioinfo/  (+info)

E-CELL: software environment for whole-cell simulation. (8/21774)

MOTIVATION: Genome sequencing projects and further systematic functional analyses of complete gene sets are producing an unprecedented mass of molecular information for a wide range of model organisms. This provides us with a detailed account of the cell with which we may begin to build models for simulating intracellular molecular processes to predict the dynamic behavior of living cells. Previous work in biochemical and genetic simulation has isolated well-characterized pathways for detailed analysis, but methods for building integrative models of the cell that incorporate gene regulation, metabolism and signaling have not been established. We, therefore, were motivated to develop a software environment for building such integrative models based on gene sets, and running simulations to conduct experiments in silico. RESULTS: E-CELL, a modeling and simulation environment for biochemical and genetic processes, has been developed. The E-CELL system allows a user to define functions of proteins, protein-protein interactions, protein-DNA interactions, regulation of gene expression and other features of cellular metabolism, as a set of reaction rules. E-CELL simulates cell behavior by numerically integrating the differential equations described implicitly in these reaction rules. The user can observe, through a computer display, dynamic changes in concentrations of proteins, protein complexes and other chemical compounds in the cell. Using this software, we constructed a model of a hypothetical cell with only 127 genes sufficient for transcription, translation, energy production and phospholipid synthesis. Most of the genes are taken from Mycoplasma genitalium, the organism having the smallest known chromosome, whose complete 580 kb genome sequence was determined at TIGR in 1995. We discuss future applications of the E-CELL system with special respect to genome engineering. AVAILABILITY: The E-CELL software is available upon request. SUPPLEMENTARY INFORMATION: The complete list of rules of the developed cell model with kinetic parameters can be obtained via our web site at: http://e-cell.org/.  (+info)

  • The first software set, Prevention Quality Indicators , was released in November 2001, and the final product, Patient Safety Indicators, will be available in late 2002. (ahrq.gov)
  • AHRQ's Inpatient Quality Indicators (IQI) software can be downloaded from the Agency's Web site at http://www.qualityindicators.ahrq.gov/data/hcup/inpatqi.htm . (ahrq.gov)
  • The IQI software uses hospital discharge data to flag potential quality problems including overly high death rates for patients admitted for conditions like acute myocardial infarction or hip fracture, or for surgical procedures including abdominal aortic aneurysm repair and coronary artery bypass graft surgery. (ahrq.gov)
  • Computer Hardware and Software Engineering BEng (H. (coventry.ac.uk)
  • Computer Hardware and Software Engineering BEng (Hons) at Coventry University is a course aimed at bridging the gap between electronics and software engineering knowledge. (coventry.ac.uk)
  • Successful graduates of the course should be able to solve problems related to both electronics and software by learning the subjects related electronic engineering, embedded systems, computer architecture and security, programming, mobile app development, machine learning, FPGA based design and system on Chip design. (coventry.ac.uk)
  • It provides a broad technical education in the hardware and software aspects of computer systems engineering and applications development. (coventry.ac.uk)
  • TCO reflects not simply the direct qualities of an software product (price tag, functionality, reliability) and also the relationship in the software to your organization?s broader list of technology platforms, mounted systems, skills along with strategic goals, and also available market along with community based solutions. (linewbie.com)
  • The software is the newest product in AHRQ's Quality Indicators series, derived from the widely used original HCUP (Healthcare Cost and Utilization Project) Quality Indicators, but refined and expanded by the UCSF-Stanford Evidence-based Practice Center under a contract with the agency. (ahrq.gov)
  • In numerous relevant respects wide open source software is unique to proprietary software package (both parties would possibly agree on that will). (linewbie.com)
  • Free software released today by the Agency for Healthcare Research and Quality (AHRQ) provides the nation's hospitals with a quick and relatively easy-to-use quality check on their inpatient care. (ahrq.gov)
  • So it's interesting to view this new report prepared to the Cabinet Office while using title "Total Charge of Ownership involving Open Source Software", containing been released within the liberal Open Govt Licence for general public sector information. (linewbie.com)
  • TCO has got to consider questions involving how software fits in the organisation and pertains to the other means including legacy devices, technology platforms along with infrastructures, skill pieces and management fashion, as well while business strategy. (linewbie.com)
  • This report is supposed to provide a new balanced assessment in the potential of wide open source software from the public sector determined by evidence collected from individuals who have taken this course and from members in the community of businesses offering support solutions to such general public bodies. (linewbie.com)
  • Thus, that they report, it is imperative that you manage expectations in order that a project that will chooses open source software is just not considered a malfunction prematurely if very easy deliver excellent assistance at substantially lower cost on day one particular. (linewbie.com)
  • SurveyMonkey was recognized by Great Place to Work® and FORTUNE as a top workplace in 2018 and 2019, and the company has also won numerous awards as a leader in global survey software, including being named among CNBC's Disruptor 50 and the Forbes Cloud 100. (surveymonkey.com)
  • 1. Progress Software Description Description Progress Software, headquartered in Bedford, MA, provides a broad range of service-oriented architecture (SOA) infrastructure products focusing on developing, deploying, integrating, and managing business applications. (slideshare.net)
  • The company offers enterprise software infrastructure products which include the Sonic, Actional, DataXtend, and Apama product families. (slideshare.net)
  • For this reason it is necessary to maintain guidelines regarding software deployment and changes to the instructional computing infrastructure. (umich.edu)
  • The IAEA Integrated Review of Infrastructure for Safety (IRIS) methodology and software tool supports the development of safety infrastructure for nuclear power programmes through self-assessment. (iaea.org)
  • Research Software Engineers will be an important part of the twenty-first century research team, and building a stable home for these skills in academia will help secure for research the benefits of a high quality, sustainable software infrastructure. (ucl.ac.uk)
  • Therefore, it's no surprise that Red Hat ranks among the ZDNet Asia Top Tech 50 companies in the software infrastructure segment which includes database management, middleware, application delivery, and systems management. (zdnet.com)
  • In order to nurture, accelerate and sustain this critical mode of scientific progress, NSF is establishing a new program, Software Infrastructure for Sustained Innovation (SI 2 ), with the overarching goal of transforming innovations in research and education into sustained software resources that are an integral part of the cyberinfrastructure. (nsf.gov)
  • It is NSF's expectation that SI 2 investment will result in robust, reliable, usable and sustainable software infrastructure that is critical to the CF21 vision and will transform science and engineering. (nsf.gov)
  • SI 2 envisions vibrant partnerships among academia, government laboratories and industry for the development and stewardship of a sustainable software infrastructure that can enhance productivity and accelerate innovation in science and engineering. (nsf.gov)
  • SSI awards target larger groups of PIs organized around common research problems as well as common software infrastructure, and will result in a sustainable community software framework. (nsf.gov)
  • In 2000, Fred Shapiro, a librarian at the Yale Law School, published a letter revealing that John Wilder Tukey 's 1958 paper "The Teaching of Concrete Mathematics" contained the earliest known usage of the term "software" found in a search of JSTOR 's electronic archives, predating the OED 's citation by two years. (wikipedia.org)
  • Another way to find software is by using the Ports Collection's built-in search mechanism. (freebsd.org)
  • The 2006 edition features several new and enhanced features, including an integrated dictionary that can use the Mac's built-in voice software to pronounce any word in an article (excellent for kids learning to read) and a Dashboard widget that allows you to perform a quick search from the desktop. (macworld.com)
  • 20B+ worth of Apache Open Source software products are made available to the public-at-large at 100% no cost, and benefit billions of users around the world. (apache.org)
  • It appears that one or more of your Adobe software products is not genuine. (adobe.com)
  • Software should be cited on the same basis as any other research product such as a paper or a book, that is, authors should cite the appropriate set of software products just as they cite the appropriate set of papers. (slideshare.net)
  • IBM® Unica® products are now a part of the omni-channel marketing and real-time personalization capabilities in the IBM Marketing Solutions software portfolio. (ibm.com)
  • Microsoft packaged software products prior to Windows 10 such as Windows, Office, and Windows Server are delivered on a CD or DVD, which includes vibrant color and 3D effects on the inner hub of the disc, as the disc is tilted. (microsoft.com)
  • Fujitsu offers a comprehensive portfolio of storage software products optimally integrated and tested with our device and solution portfolio to make efficient use of your storage base. (fujitsu.com)
  • In response, every software company, ranging from the database management to application management tool companies, has focused on making its products more reliable, easier to use, and cheaper to operate. (zdnet.com)
  • Review the software license agreements for currently shipping Apple products by selecting the appropriate product below. (apple.com)
  • Your use of Apple software or hardware products is based on the software license and other terms and conditions in effect for the product at the time of purchase. (apple.com)
  • Become a member of DuraSpace in 2016 to support the continued advancement of the DSpace open source software projects which serve YOUR vital interests in scholarly ecosystem. (dspace.org)
  • In limited countries and regions worldwide, you may receive your Office 2016 backup software on a USB device that includes vibrant color and 3D effects as the USB device is tilted. (microsoft.com)
  • Depending on scale and complexity, the spectrum of software systems can span from operating systems for devices to large networked systems that consist of thousands of servers. (microsoft.com)
  • Software enables highly complex activities - such satellite precision manoeuvres, autonomous navigation of rovers on a planetary terrain - and provides a means to recover from malfunctions and compensate for hardware equipment defects. (esa.int)
  • Qualin Software is an ISO 9001-2000 Certified Company. (archive.org)
  • The software runs on a PC under Windows 98/NT/2000/XP to provide access to the data through a single GUI. (ornl.gov)
  • The software runs on a PC under Windows 98/NT/2000/XP. (ornl.gov)
  • With various analytical and computing technologies, such as pattern recognition, machine learning, data mining, information visualization and large-scale data computing & processing, software analytics is to enable software practitioners to perform effective and efficient data exploration and analysis in order to obtain insightful and actionable information for data-driven tasks in engineering software and services. (microsoft.com)
  • A NIOSH analytical software system for use in occupational cohort mortality studies. (cdc.gov)
  • Please note the link to the NIOSH-IREP software website will change on February 17, 2021. (cdc.gov)
  • To determine probability of causation for a cancer case under the Act , the Department of Labor (DOL) uses a computer software application NIOSH has developed in collaboration with the National Cancer Institute, called NIOSH-IREP (Interactive RadioEpidemiological Program) external icon . (cdc.gov)
  • NIOSH is responsible for maintaining and updating this software and the scientific elements (cancer risk models) that it uses. (cdc.gov)
  • An outline ( algorithm ) for what would have been the first piece of software was written by Ada Lovelace in the 19th century, for the planned Analytical Engine . (wikipedia.org)
  • Forex forecasting software is an analytical tool used to help currency traders with foreign exchange trading analysis through charts and indicators. (investopedia.com)
  • Set operational specifications and formulate and analyze software requirements. (bls.gov)
  • Forex charting software helps traders analyze foreign currency pairs price trends, enabling them to make informed trading decisions. (investopedia.com)
  • We laid a special emphasis for our streamlined software engineering process oriented approach to our work and hand hold our customers through the various stages of the product life cycle with our team,comprising of proven and certified resources as solution architects ,technology leads, software analysts,designers,software engineers and Quality assurance professionals. (archive.org)
  • Our solution has been to create a dedicated group of Research Software Engineers at UCL who combine academic research experience with an appreciation of good software engineering principles. (ucl.ac.uk)
  • ISS will not deploy requested software without proof of appropriate licensing and will require a copy of the license to be submitted with the software request. (umich.edu)
  • It can start integrating code, run automated tests, check for cyber vulnerabilities and deploy software to production. (prnewswire.com)
  • SSE awards target small groups that will create and deploy robust software elements for which there is a demonstrated need, encapsulating innovation in science and engineering. (nsf.gov)
  • The agile method is more analogous to how things actually work in today's software world, where nothing is black or white. (acquia.com)
  • It was the User Groups that charged for the services of copying and distributing the software. (tripod.com)
  • We intend to maintain and strengthen our position in software services market by continuously developing and expanding, improving our resources and technological know how in the technology and management consulting domains. (archive.org)
  • Users are (almost) always right because ultimately they pay for the software and services in various ways. (microsoft.com)
  • Usage data collected from the real world reveals how users interact with software and services. (microsoft.com)
  • Dongmei Zhang, Data-Driven Performance Management in Practice for Online Services , invited talk at the second International Symposium on High Confidence Software ( ISHCS 2012 ) , Qingdao, Shandong, China, October 29, 2012. (microsoft.com)
  • HP is planning to offer pre-packaged hardware, software, and services bundles aimed at moving Oracle applications to private clouds starting with PeopleSoft and gradually expanding to Oracle's Fusion and E-Business applications. (crn.com)
  • The software is built to allow telecom and Internet service providers to get to market quickly and start receiving revenues from new services in an optimal manner. (internetnews.com)
  • Basically, the software allows these ISPs to bill for ancillary services, as well as help capture demographic information and track user activities. (internetnews.com)
  • In a world where threats evolve fast, software must evolve faster,' said Todd Probert , vice president for Raytheon Intelligence, Information and Services. (prnewswire.com)
  • Donnie MacColl , Team Leader and Director of Technical Services at Halcyon Software said, 'We are very proud to have completed the challenge despite gruelling circumstances. (prnewswire.com)
  • Kerr Consulting (Leader in IT services, accounting and enterprise resource planning (ERP), customer relationship management (CRM) and human resources software) acquires Software Link. (prweb.com)
  • Founded in 1987, Kerr Consulting is a full-service provider of IT services including accounting and enterprise resource planning (ERP) solutions, along with customer relationship management (CRM) and human resources software. (prweb.com)
  • If you continue to take no action, software functionality may be restricted until the non-genuine software issue is resolved. (adobe.com)
  • The added value of software to space systems has increased greatly in recent decades, reflecting the ever growing functionality and autonomy of spacecraft and the amount of mission data to be collected and processed. (esa.int)
  • Different suppliers of this technology will offer various features and software functionality. (investopedia.com)
  • Bundled software, give users advanced functionality to ensure that their devices are secure, up-to-date and have improved performance. (acer.com)
  • The company operates as a genealogy ( family tree ) software developer exclusively for macOS and iOS . (wikipedia.org)
  • Industry analysts expect the software industry to consolidate further as the players race to expand their product portfolio and international reach, and no sector will be immune. (zdnet.com)
  • Forex forecasting software provides graphs of currency pairs that display price changes over time as well as indicator overlays including moving averages, which help analysts and traders to determine appropriate and profitable entry and exit points for their forex trades. (investopedia.com)
  • As with charting software used for trading other securities, forex forecasting software is applied primarily by technical analysts to forecast future price movements. (investopedia.com)
  • Analysts expect consistent profit for BMC Software (BMC) when the company reports its fourth quarter results on Wednesday, May 9, 2012. (forbes.com)
  • The majority of analysts (63.6%) rate BMC Software as a buy. (forbes.com)
  • Dongmei Zhang, Software Analytics in Practice - Approaches and Experiences, Keynote at the 11th International Conference on Predictive Models and Data Analytics in Software Engineering (PROMISE 2015), Beijing, China, October 21, 2015. (microsoft.com)
  • Dongmei Zhang and Tao Xie, Software Analytics - Achievements and Challenges , Tutorial at the 22nd ACM SIGSOFT International Symposium on Foundations of Software Engineering (FSE 2014) , Hong Kong, China, November 2014. (microsoft.com)
  • Dongmei Zhang, Software Analytics in Practice - Approaches and Experiences , Keynote at the 12th National Software Application Conference ( NASAC 2013 ), Tianjin, China, November 9, 2013. (microsoft.com)
  • Dongmei Zhang, Software Analytics in Practice - Approaches and Experiences , Keynote at the 9th Working Conference on Mining Software Repositories ( MSR2012 ) , Zurich, Switzerland, June 2, 2012. (microsoft.com)
  • The application software layer interfaces with the operating system , which in turn communicates with the hardware . (wikipedia.org)
  • The FVS Software Setup file covers all Regions of the National Forest System. (fed.us)
  • System 6.0.8 was the last System Software distributed through this manner (Though there is a System 6.0.9- which I can not find and many denie of its exisitance). (tripod.com)
  • System 7 updates and enhancements are also distributed freely, but you need the orginal System Software to 'legalize' these system add-ons. (tripod.com)
  • DCAL is a comprehensive software system for the calculation of tissue dose and subsequent health risk from intakes of radionuclides or exposure to radionuclides present in environmental media. (ornl.gov)
  • The Regulatory Authority Information System (RAIS) is a software application developed by the IAEA to assist Member States in managing their regulatory control programmes in accordance with IAEA Safety Standards and guides. (iaea.org)
  • This version became a Mac OS X native application, providing users of OS X and prior versions of the Macintosh operating system the ability to utilize the software. (wikipedia.org)
  • System quality such as reliability, performance and security, is the key to success of modern software systems. (microsoft.com)
  • Software is the term given to coded sets of instructions that tell the system what to do in a given situation. (esa.int)
  • Thus, the software represents the "intelligence" of a certain system. (esa.int)
  • Visual Basic for Applications (VBA) is part of Microsoft's legacy software, Visual Basic, built to help write programs for the Windows operating system. (investopedia.com)
  • The senator's site makes extensive use of a JavaScript menu system developed by Milonic Solutions , a software company based in the United Kingdom. (wired.com)
  • Because if Hatch's terminator system embraced software as well as music, his servers would be targeted for destruction. (wired.com)
  • Keep up with the ASF's news and announcements by subscribing to the Apache Announcements List , as well as following the Foundation Blog , Apache Weekly News Round-Ups , @TheASF on Twitter , The Apache Software Foundation on LinkedIn , and on Feathercast , the voice of the ASF. (apache.org)
  • For more information on the Intel® IXDPG425 Network Gateway Reference Platform, see http://www.intel.com/content/www/us/en/intelligent-systems/previous-generation/gateway-reference-platform.html . (intel.com)
  • The zip files can be obtained from http://www.intel.com/content/www/us/en/intelligent-systems/previous-generation/monta-vista-linux-3-1-ixdpg425-lsp-support.html . (intel.com)
  • Software_Secure's library does not contain any public content. (screencast.com)
  • The first theory about software-prior to the creation of computers as we know them today-was proposed by Alan Turing in his 1935 essay On Computable Numbers, with an Application to the Entscheidungsproblem (decision problem). (wikipedia.org)
  • The software also supports a wide array of plugins that enable customization of the application and integration with other aspects of the Mac OS X environment. (wikipedia.org)
  • internationally, it draws on the broader Progress Software sales force and Application Partner channels. (slideshare.net)
  • The ports can be searched by application name or by software category. (freebsd.org)
  • Growth is expected to be higher in the application life cycle management segment as compared to the more mature markets such as the database management software markets, according to research firm IDC. (zdnet.com)
  • Software MacKiev has redesigned World Book 2006 from the ground up as a Mac OS X application. (macworld.com)
  • Founded in September 1980, BMC Software makes enterprise management software designed to enable companies to better maintain their networks.The company holds 72 software technology patents and is best known for its PATROL application management suite. (zdnet.com)
  • The company holds 72 software technology patents and is best known for its PATROL application management suite. (zdnet.com)
  • Unlock more value from your software investment with enhanced and premium service options, including support from designated software experts. (cisco.com)
  • Software tools to support the standardized coding of industry and occupation text found on employment, vital statistics, cancer registries and other record systems. (cdc.gov)
  • Add to this host of features, control of the radio, packet cluster support, rotator control and the ability to network logging computers and you have a rough idea of what this sort of software can do for you. (qsl.net)
  • Unless otherwise agreed upon end user support and training on requested software is the responsibility of the submitter. (umich.edu)
  • Intel may make changes to the Software, or to items referenced therein, at any time without notice, but is not obligated to support, update, or provide training for the Software. (intel.com)
  • The patches are used to update Intel IXP400 software, adding support for the Intel® IXDPG425 platform. (intel.com)
  • The research, sponsored by an NSF ITR, aims at developing effective schemes for coordinating multi-agent teams of heterogeneous robots, software agents and people in disaster response. (cmu.edu)
  • The earliest known publication of the term "software" in an engineering context was in August 1953 by Richard R. Carhart, in a Rand Corporation Research Memorandum. (wikipedia.org)
  • Software should be considered a legitimate and citable product of research. (slideshare.net)
  • The UCL Research Programming Hub brings together research groups across the college who develop software for research. (ucl.ac.uk)
  • However, a lack of appreciation for the significance of software as a research output often leads to software created in research institutions being treated as a secondary concern. (ucl.ac.uk)
  • Research software is often developed quickly to solve one-off problems, leading to fragile code that is generally not sustainable or usable beyond the lifetime of a given project, and is hard for other researchers to read and understand. (ucl.ac.uk)
  • We also work with partners such as the Software Sustainability Institute to advocate on behalf of research programmers for software as a first-class research output. (ucl.ac.uk)
  • We are keen to engage with research groups from across UCL who are developing their own software, to learn about existing projects and to understand the needs of the research community. (ucl.ac.uk)
  • These three companies led the worldwide relational database management software market for 2004, according to research analyst firm IDC. (zdnet.com)
  • SI 2 is a long-term investment focused on catalyzing new thinking, paradigms, and practices in using software to understand natural, human, and engineered systems. (nsf.gov)
  • Turnaround time will vary depending on ISS staff availability and the complexity of the deployment issues the software presents. (umich.edu)
  • As the sophistication and on-board intelligence of spacecraft has increased, e.g. to become more autonomous from ground, so too has the size and complexity of their associated software programs, stretching to hundreds of thousands of lines of code (and up to one million lines of code for the Jules Verne ATV). (esa.int)
  • Halcyon Software reduces the complexity of systems monitoring and automation. (prnewswire.com)
  • Requested software must function in the currently deployed Macintosh and Windows environments. (umich.edu)
  • When you purchase software such as Windows, Office, or Windows Server on its own (not preinstalled on a PC), this is called packaged software. (microsoft.com)
  • Your Windows 10 Microsoft packaged software product is delivered with Windows on a USB device which includes vibrant color and 3D effects as the USB device is tilted. (microsoft.com)
  • Tarantella Inc. and CodeWeavers Inc. partnered last week in order to integrate Tarantella's Enterprise 3 remote access software with CodeWeavers' Linux-based CrossOver Office Server Edition, which lets users access Microsoft Office apps via a Java-enabled Web browser without having Windows on their desktops. (informationweek.com)
  • Is the software Windows, Mac or web-based? (investopedia.com)
  • He showed the Windows version of the software to Wired News, and said he's previously given private demonstrations to the US Council of Mayors, the National Governors Association, and the National League of Cities -- all groups that are Net-tax proponents. (wired.com)
  • For a list of independent antivirus software vendors, please visit http://www.microsoft.com/windows/antivirus-partners/windows-7.aspx . (microsoft.com)
  • To purchase genuine Adobe software, visit the Adobe choose a plan page or Contact us . (adobe.com)
  • You can check the status of the software on your machine by reviewing the results at the bottom of this page. (adobe.com)
  • Welcome to the VMS' Software Page. (tripod.com)
  • The team has developed several open source software projects, which can be found at the LANL-Seismoacoustics GitHub page. (lanl.gov)
  • But, military leaders are asking industry to change how they develop software, by taking a page from the consumer technology world. (prnewswire.com)
  • In September, BMC Software announced the availability of the BMC Performance Manager Developers Kit, and in October, it introduced BMC Identity Management Suite, version 5.0. (zdnet.com)
  • Raytheon software developers working on military and space programs now have access to the same coding tools and facilities used in the consumer technology world. (prnewswire.com)
  • Invalid serial numbers are likely the result of using non-genuine software. (adobe.com)
  • You can quickly resolve this problem by purchasing genuine Adobe software. (adobe.com)
  • Only genuine software gives you ongoing access to the latest features and updates so you can avoid performance snags and malware risks. (adobe.com)
  • Unfortunately, you may only discover the software you're using is non-genuine when you try to re-activate or reinstall it. (adobe.com)
  • What is non-genuine software? (adobe.com)
  • Non-genuine software is software that is not legally licensed. (adobe.com)
  • Non-genuine software may also contain malware or viruses posing risks to you, your productivity and your security. (adobe.com)
  • We strongly recommend you remove the non-genuine software on your machine and replace it with genuine Adobe software. (adobe.com)
  • A​s part of Adobe's efforts to reduce the supply of counterfeit and non-genuine software, we actively pursue reports we receive of websites or resellers selling counterfeit or non-genuine software. (adobe.com)
  • To ensure you avoid the risks associated with non-genuine software, we strongly recommend you uninstall your non-genuine software and replace it with genuine Adobe software. (adobe.com)
  • We understand this may be an unexpected expense, that's why we're offering exclusive prices to users like you who may have unknowingly obtained non-genuine software. (adobe.com)
  • Learn more about features included with genuine Microsoft software, including the packaging, installation CD/DVD/USB, product key labels, and the Certificate of Authenticity (COA). (microsoft.com)
  • Berlin, February 20, 2020 - The Document Foundation announces LibreOffice 6.3.5, the 5th minor release of the LibreOffice 6.3 family, targeted at individuals using the software for production purposes, who are invited to update their current version. (libreoffice.org)
  • Software citations should facilitate identification of, and access to, the specific version of software that was used. (slideshare.net)
  • Software identification should be as specific as necessary, such as using version numbers, revision numbers, or variants such as platforms. (slideshare.net)
  • This is the current version (Ver 2.1) of the viewer software. (ornl.gov)
  • Software Version Upgrades are an important benefit of current Maintenance that protect your Symantec software investment and are essential to continued security protection and optimal product performance. (symantec.com)
  • Symantec automatically notifies eligible customers about Software Version Upgrades. (symantec.com)
  • Upon a major release of a new software version, Symantec notifies its eligible customers by email. (symantec.com)
  • Some notifications will direct customers to the MySymantec customer portal to access their Software Version Upgrade (using the VU Notification ID provided). (symantec.com)
  • There is no need to upgrade your software as you are always on the latest version: your product or service is continuously updated giving you seamless access to the latest features, enhancements and technological innovations. (symantec.com)
  • Please be aware that the software license that accompanies the product at the time of purchase may differ from the version of the license you can review here. (apple.com)
  • However, the software's license stipulates that the user must register the software to receive a licensing code, and provide a link in the source code to Milonic's website. (wired.com)
  • As a disclaimer, this is my experience, and not a broad generalization about enterprise work environments, or the software industry as a whole. (archive.org)
  • we work collaboratively, providing the tools, advice and training researchers need in order to follow best practice and continue to develop sustainable software in future. (ucl.ac.uk)
  • Software must work correctly first time in orbit, and getting it right is crucial to mission success: software bugs have been the doom of many spacecraft, going back to the earliest days of space exploration. (esa.int)
  • Acer has been hard at work developing software to make your digital life a breeze - in addition to our own offerings, we've partnered with the best in the business to bring you all the tools you'll ever need. (acer.com)
  • When do you need the software to work? (google.com)
  • The software is only intended to assist the user in assembling and organizing the information required to make medical decisions, and cannot be substituted for competent and informed professional judgment. (cdc.gov)
  • Software citations should facilitate access to the software itself and to its associated metadata, documentation, data, and other materials necessary for both humans and machines to make informed use of the referenced software. (slideshare.net)
  • Care is taken to make sure that all software deployed is ready to use with minimum configuration. (umich.edu)
  • We generally do not make software recommendations of this sort. (dynamicdrive.com)
  • Forex forecasting software, while not guaranteed to be entirely accurate, makes it easier to apply technical analysis , and make predictions about the market's direction. (investopedia.com)
  • Almost all hardware devices that can play Vorbis, and many software implementations on embedded devices (such as mobile phones) use Tremor or some descendant. (wikipedia.org)
  • Anton runs specific software written for its specialized hardware and is not included here. (psc.edu)
  • Historically, government agencies - particularly the military - would develop software the same way they developed hardware, a process that could take years and sometimes decades. (prnewswire.com)
  • Software is an integral part of the computation paradigm and a primary modality for realizing the CF21 vision. (nsf.gov)
  • What Open Source Software Do You Use? (apache.org)
  • Apache Projects are defined by collaborative, consensus-based processes , an open, pragmatic software license and a desire to create high quality software that leads the way in its field. (apache.org)
  • From Accumulo to Zookeeper, if you are looking for a rewarding experience in Open Source and industry leading software, chances are you are going to find it here. (apache.org)
  • This directive for IT to do more with less also explains the huge growing interest in open-source software. (zdnet.com)
  • Oracle CEO Larry Ellison, who has been vocal about supporting open source, hopes to double the software giant's revenues to US$30 billion over the next few years, and he plans to achieve it with an acquisition strategy. (zdnet.com)
  • See the attached file for the current list of site licensed software. (washington.edu)
  • Site licensed software can be installed on UW-owned equipment only. (washington.edu)
  • Requesting parties are encouraged to test software packages in the classroom computing environment before purchasing a site license, in order to identify potential conflicts. (umich.edu)
  • In no event shall the Royal Society of Chemistry be liable for any direct, indirect, incidental, special, consequential damages whatsoever including, without limitation, damages for loss of use, data or profits, arising out of or in any way connected with the use of performance of this software and related graphics obtained through this web site. (rsc.org)
  • Qualin software repeatedly delivered all its projects on time and highest level of quality with in budgets with its excellent and proven outsourcing framework.Qualin software focuses its impetus towards a blend of the process and technology into various functional domains and thus enriching its quality delivery. (archive.org)
  • Ideally, requested software will need a license agreement with enough seats to cover all ISS workstations or the agreement must allow for "keying", a process that permits only a specific number of instances of the program to be run at any one time. (umich.edu)
  • SPIROLA software is an easy-to-use visual and quantitative tool intended to assist the health care provider in monitoring and interpreting computerized longitudinal spirometry data for individuals as well as for a group. (cdc.gov)
  • There are neither warranties expressed or implied with this software tool. (cdc.gov)
  • Reunion 6 was announced on November 1998 and saw the genealogy software change to include pictures into the family card view and introduced the Match & Merge tool that can be used to detect and remove duplicate records in the family file. (wikipedia.org)
  • The goal of the SI 2 program is to create a software ecosystem that includes all levels of the software stack and scales from individual or small groups of software innovators to large hubs of software excellence. (nsf.gov)
  • The Certificate of Authenticity (COA) label is used on the outside of the retail boxed software and explains what the product is, its country of intended use and country of origin. (microsoft.com)
  • Be certain to read the applicable terms carefully before you install the software or use the product. (apple.com)
  • A Kinetic Monte Carlo software package written in Fortran, for simulating molecular phenomena on catalytic surfaces. (ucl.ac.uk)
  • The environment management package Module is essential for running software on PSC systems. (psc.edu)
  • However, it is Software MacKiev's implementation of World Book that shines, by offering a user-friendly interface and more-advanced tools. (macworld.com)
  • RTN ) has developed a virtual software factory - a mix of physical coding spaces, cloud-based tools and software experts - to quickly deliver new capabilities to the military. (prnewswire.com)
  • Instructors that require software not provided by DoIT will need to purchase licenses and ensure that DoIT has the license information. (google.com)