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Soft Tissue NeoplasmsNeoplasms, Connective and Soft TissueNeoplasms, Bone TissueNeoplasms, Gonadal TissueNeoplasms, Adipose TissueNeoplasms, Nerve TissueNeoplasms, Connective TissueNeoplasms, Vascular TissueNeoplasms, Fibrous TissueSarcomaNeoplasms, Muscle TissueSoft Tissue InjuriesSoft Tissue InfectionsLiposarcoma, MyxoidLipomaConnective TissuePalatal NeoplasmsCystadenomaAdenoma, PleomorphicTissue BanksBiopsy, Fine-NeedleThoraxNeoplasms, Second PrimaryInternational Classification of DiseasesConnective Tissue DiseasesNeoplasmsManuscripts, MedicalVaccinationPapillomavirus InfectionsUterine Cervical DiseasesPapillomaviridaeUterine Cervical NeoplasmsPapillomavirus VaccinesAnus Diseasesraf KinasesProto-Oncogene Proteins c-rafNeurofibromatosis 1ras ProteinsNeoplasm TransplantationGliomaNeurofibromatosis 2Contrast MediaCapillary PermeabilityGadolinium DTPAMagnetic Resonance ImagingMagnetic Resonance AngiographyImage EnhancementBlood VolumeHeavy Ion RadiotherapyHeavy IonsCarbonChordomaRelative Biological Effectiveness
Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Neoplasms, Connective and Soft Tissue: Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.Neoplasms, Bone Tissue: Neoplasms composed of bony tissue, whether normal or of a soft tissue which has become ossified. The concept does not refer to neoplasms located in bones.Neoplasms, Gonadal Tissue: Neoplasms composed of tissues of the OVARY or the TESTIS, not neoplasms located in the ovaries or testes. Gonadal tissues include GERM CELLS, cells from the sex cord, and gonadal stromal cells.Neoplasms, Adipose Tissue: Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.Neoplasms, Nerve Tissue: Neoplasms composed of nerve tissue. This concept does not refer to neoplasms located in the nervous system or its component nerves.Neoplasms, Connective Tissue: Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.Neoplasms, Vascular Tissue: Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.Neoplasms, Fibrous Tissue: Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.Neoplasms, Muscle Tissue: Neoplasms composed of muscle tissue: skeletal, cardiac, or smooth. The concept does not refer to neoplasms located in muscles.Soft Tissue Injuries: Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".Soft Tissue Infections: Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)Liposarcoma, Myxoid: A liposarcoma containing myxomatous tissue. (Dorland, 27th ed)Lipoma: A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.Connective Tissue: Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.Palatal Neoplasms: Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Tissue Banks: Centers for acquiring, characterizing, and storing organs or tissue for future use.Biopsy, Fine-Needle: Using fine needles (finer than 22-gauge) to remove tissue or fluid specimens from the living body for examination in the pathology laboratory and for disease diagnosis.Thorax: The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)Neoplasms, Second Primary: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.International Classification of Diseases: A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Manuscripts, MedicalVaccination: Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.Papillomavirus Infections: Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.Uterine Cervical Diseases: Pathological processes of the UTERINE CERVIX.Papillomaviridae: A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.Papillomavirus Vaccines: Vaccines or candidate vaccines used to prevent PAPILLOMAVIRUS INFECTIONS. Human vaccines are intended to reduce the incidence of UTERINE CERVICAL NEOPLASMS, so they are sometimes considered a type of CANCER VACCINES. They are often composed of CAPSID PROTEINS, especially L1 protein, from various types of ALPHAPAPILLOMAVIRUS.Anus Diseasesraf Kinases: A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.Proto-Oncogene Proteins c-raf: A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).ras Proteins: Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.Neoplasm Transplantation: Experimental transplantation of neoplasms in laboratory animals for research purposes.Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)Neurofibromatosis 2: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.Contrast Media: Substances used to allow enhanced visualization of tissues.Capillary Permeability: The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.Gadolinium DTPA: A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Image Enhancement: Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Heavy Ion Radiotherapy: The use of a heavy ion particle beam for radiotherapy, such as the HEAVY IONS of CARBON.Heavy Ions: Positively-charged atomic nuclei that have been stripped of their electrons. These particles have one or more units of electric charge and a mass exceeding that of the Helium-4 nucleus (alpha particle).Carbon: A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.Chordoma: A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)Relative Biological Effectiveness: The ratio of radiation dosages required to produce identical change based on a formula comparing other types of radiation with that of gamma or roentgen rays.

L-[1-11C]-tyrosine PET to evaluate response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcoma and skin cancer. (1/1415)

PET with L-[1-11C]-tyrosine (TYR) was investigated in patients undergoing hyperthermic isolated limb perfusion (HILP) with recombinant tumor necrosis factor alpha (rTNF-alpha) and melphalan for locally advanced soft-tissue sarcoma and skin cancer of the lower limb. METHODS: Seventeen patients (5 women, 12 men; age range 24-75 y; mean age 52 y) were studied. TYR PET studies were performed before HILP and 2 and 8 wk afterwards. The protein synthesis rates (PSRs) in nanomoles per milliliter per minute were calculated. After final PET studies, tumors were resected and pathologically examined. Patients with pathologically complete responses (pCR) showed no viable tumors after treatment. Those with pathologically partial responses (pPR) showed various amounts of viable tumors in the resected tumor specimens. RESULTS: Six patients (35%) showed a pCR and 11 patients (65%) showed a pPR. All tumors were depicted as hot spots on PET studies before HILP. The PSR in the pCR group at 2 and 8 wk after perfusion had decreased significantly (P < 0.05) in comparison to the PSR before HILP. A significant difference was found in PSR between the pCR and pPR groups at 2 and at 8 wk (P < 0.05). Median PSR in nonviable tumor tissue was 0.62 and ranged from 0.22 to 0.91. With a threshold PSR of 0.91, sensitivity and specificity of TYR PET were 82% and 100%, respectively. The predictive value of a PSR > 0.91 for having viable tumor after HILP was 100%, whereas the predictive value of a PSR < or = 0.91 for having nonviable tumor tissue after HILP was 75%. The 2 patients in the pPR groups with a PSR < 0.91 showed microscopic islets of tumor cells surrounded by extensive necrosis on pathological examination. CONCLUSION: Based on the calculated PSR after HILP, TYR PET gave a good indication of the pathological outcome. Inflammatory tissue after treatment did not interfere with viable tumor on the images, suggesting that it may be worthwhile to pursue TYR PET in other therapy evaluation settings.  (+info)

FDG and L-[1-11C]-tyrosine imaging of soft-tissue tumors before and after therapy. (2/1415)

This study was undertaken to investigate the relationship of PET using fluorodeoxyglucose (FDG) or L-[1-11C]-tyrosine (TYR) with histopathologic findings in soft-tissue tumors, before and after therapy. Histopathologic parameters that were studied were tumor grade, mitotic rate, proliferation activity and amount of necrosis. METHODS: PET with either FDG or TYR was performed in 55 patients with a lesion suspected to be a malignant soft-tissue tumor. In 28 patients, a second PET study was performed after therapy. Metabolic rate of glucose consumption (MRglc) and protein synthesis rate (PSR) were calculated. Histologic parameters were obtained from a biopsy specimen that was taken just after the first PET study and from the tumor remnant that was resected after therapy. RESULTS: MRglc correlated with tumor grade (r = 0.71) and mitotic rate (r = 0.68) but not with proliferation or necrosis. After therapy, there was no longer a correlation with mitotic rate. PSR correlated with tumor grade (r = 0.53), mitotic rate (r = 0.73) and proliferation (r = 0.66). After therapy, correlation with mitosis and proliferation had improved, and a negative correlation was found between PSR and necrosis (r = -0.74). CONCLUSION: These results validate the use of both FDG and TYR to give an in vivo indication of histologic tumor parameters. However, FDG gives a better indication of tumor grade, whereas TYR is more accurate in predicting mitotic rate and proliferation, especially after therapy. FDG may therefore not be the most suited tracer for monitoring therapy. TYR might be more appropriate for that purpose.  (+info)

Subcutaneous sacrococcygeal myxopapillary ependymoma. (3/1415)

We report a case of myxopapillary ependymoma presenting as a primary tumor of the subcutaneous tissue in the sacrococcygeal region. The mass was large, well-encapsulated, lobulated, and multiseptated, with varying signal intensity on T1- and T2-weighted MR images caused by hemorrhagic necrosis, blood degradation products, and calcification. Only a small viable portion enhanced after administration of contrast material. Multiple lobules formed from fibrous septa and dystrophic calcification also characterize this tumor.  (+info)

Lymphangiosarcomas in cats: a retrospective study of 12 cases. (4/1415)

Clinical, macroscopic, and histologic features of 12 lymphangiosarcomas in cats are described. Nine tumors were located in the subcutaneous tissue at the caudoventral abdominal wall (eight cats) or in the neck (one cat). The remaining three cats had lymphangiosarcomas around the cranial mesenteric artery (two cats) or precardial in the mediastinum (one cat). Macroscopically, the tumors were noncircumscribed, white, edematous, and intermixed with fat tissue. Histologic features varied from cleft-forming and cavernous growth to papilliform and solid patterns. Follow-up data were available for seven cats with subcutaneous lymphangiosarcomas. All these cats died or were euthanatized within 6 months after surgery because of poor wound healing, local recurrence, or distant metastases. The cats with abdominal or thoracic masses were either euthanatized at surgery or within 6 months after the first surgery because of recurrent chylothorax, chyloperitoneum, or distant metastases.  (+info)

Clinical and radiological aspects of idiopathic diabetic muscle infarction. Rational approach to diagnosis and treatment. (5/1415)

The systemic effects of diabetes mellitus are well recognised. The heart, kidney, central and peripheral nervous systems, and the distal parts of the limbs are often the site of end-organ damage resulting from ischaemia. Infarction of large muscle groups in the limb, not associated with gangrene, is uncommon. There have been few reported cases other than radiological descriptions of diabetic muscle infarcts. While previous reports have illustrated some of the clinical and radiological characteristics of this condition, the paucity of published cases makes it difficult to determine the most appropriate methods of diagnosis and treatment. During a five-year period we treated 14 patients with diabetes mellitus, aged from 32 to 59 years, who were referred to a musculoskeletal oncology service for suspected soft-tissue sarcoma, but were subsequently found to have a diabetic muscle infarct. Closed needle biopsy was performed in 13 without complications. In 12 patients, the symptoms resolved without surgical treatment.  (+info)

Color Doppler sonography of focal lesions of the skin and subcutaneous tissue. (6/1415)

We evaluated with color Doppler sonography 71 visible and palpable nodules of the skin and subcutaneous tissue from 51 patients. The nodules were classified as avascular (type I), hypovascular with a single vascular pole (type II), hypervascular with multiple peripheral poles (type III), and hypervascular with internal vessels (type IV). Of the 32 malignant nodules, 9% showed a type I pattern, 50% had a type III pattern, and 41% had a type IV pattern; of the 39 benign nodules, 86% showed a type I pattern and 14% had a type II pattern. The sensitivity and specificity of hypervascularity in malignant lesions were 90% and 100%, respectively, whereas the sensitivity and specificity of hypovascularity in benign lesions were 100% and 90%, respectively. The authors conclude that color Doppler sonography is able to increase the specificity of ultrasonography in the evaluation of nodular lesions of the skin.  (+info)

Pulmonary metastases from soft tissue sarcoma: analysis of patterns of diseases and postmetastasis survival. (7/1415)

OBJECTIVE: To report the patterns of disease and postmetastasis survival for patients with pulmonary metastases from soft tissue sarcoma in a large group of patients treated at a single institution. Clinical factors that influence postmetastasis survival are analyzed. SUMMARY BACKGROUND DATA: For patients with soft tissue sarcoma, the lungs are the most common site of metastatic disease. Although pulmonary metastases most commonly arise from primary tumors in the extremities, they may arise from almost any primary site or histology. To date, resection of disease has been the only effective therapy for metastatic sarcoma. METHODS: From July 1982 to February 1997, 3149 adult patients with soft tissue sarcoma were admitted and treated at Memorial Sloan-Kettering Cancer Center. During this interval, 719 patients either developed or presented with lung metastases. Patients were treated with resection of metastatic disease whenever possible. Disease-specific survival was the endpoint of the study. Time to death was modeled using the method of Kaplan and Meier. The association of factors to time-to-event endpoints was analyzed using the log-rank test for univariate analysis and the Cox proportional hazards model for multivariate analysis. RESULTS: The overall median survival from diagnosis of pulmonary metastasis for all patients was 15 months. The 3-year actuarial survival rate was 25%. The ability to resect all metastatic disease completely was the most important prognostic factor for survival. Patients treated with complete resection had a median survival of 33 months and a 3-year actuarial survival rate of 46%. For patients treated with nonoperative therapy, the median survival was 11 months. A disease-free interval of more than 12 months before the development of metastases was also a favorable prognostic factor. Unfavorable factors included the histologic variants of liposarcoma and malignant peripheral nerve tumors and patient age older than 50 years at the time of treatment of metastasis. CONCLUSIONS: Resection of metastatic disease is the single most important factor that determines outcome in these patients. Long-term survival is possible in selected patients, particularly when recurrent pulmonary disease is resected. Surgical excision should remain the treatment of choice for metastases of soft tissue sarcoma to the lung.  (+info)

The enigma of desmoid tumors. (8/1415)

OBJECTIVE: To analyze patients with recurrent extremity desmoids, in whom the surgical therapeutic option was either major amputation or observation. SUMMARY BACKGROUND DATA: The biology and natural history of desmoid tumors are an enigma. These tumors invade surrounding structures and recur locally but do not metastasize. The morbidity of treating these tumors in the context of their relatively benign biology is uncertain. METHODS: Between July 1982 and June 1998, the authors treated and prospectively followed 206 patients with extremity desmoid tumors. All patients underwent standardized surgical resection, the surgical goal always being complete resection with negative margins. When tumors recurred, they were evaluated for reresection. Amputation was considered when resection was not possible because of neurovascular or major bone involvement, or in the presence of a functionless, painful extremity. RESULTS: During this period, 22 patients had disease that was not resectable without amputation. This was out of a total of 115 patients with primary disease and 91 patients with recurrent disease. All recurrences were local; in no patient did metastasis develop. In this group of 22 patients with unresectable disease, 7 underwent amputation and 15 did not. These 15 patients were followed, alive with disease, having no surgical resection. Four patients received systemic treatment with tamoxifen and nonsteroidal antiinflammatories, three received systemic cytotoxic chemotherapy, and two received both tamoxifen and chemotherapy. Six patients received no systemic treatment. The range of follow-up was 25 to 92 months. In all patients, there was no or insignificant tumor progression; in three patients who underwent observation alone, there was some regression of tumor. During follow-up, no patient has required subsequent amputation, and no patient has died from disease. CONCLUSIONS: In desmoid tumors, aggressive attempts at achieving negative resection margins may result in unnecessary morbidity. Function- and structure-preserving procedures should be the primary goal. In select patients, whose only option is amputation, it may be prudent to observe them with their limb and tumor intact.  (+info)

Malignant soft tissue neoplasms. Problems with combined therapy. Radiologic diagnosis and radiotherapy]. - Semantic ScholarMalignant soft tissue neoplasms. Problems with combined therapy. Radiologic diagnosis and radiotherapy]. - Semantic Scholar
Semantic Scholar extracted view of [Malignant soft tissue neoplasms. Problems with combined therapy. Radiologic diagnosis and radiotherapy]. by Hildegard Poppe
Musculoskeletal, bone, muscle, nerves and other soft tissues | 7.5 Soft tissues : Case 7.5.4 Malignant soft tissue tumors |...Musculoskeletal, bone, muscle, nerves and other soft tissues | 7.5 Soft tissues : Case 7.5.4 Malignant soft tissue tumors |...
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Soft Tissue NeoplasmsSoft Tissue Neoplasms
... On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is provided.
Orthopaedic Oncology: Bone Cancer Benign Tumors and soft tissue neoplasms - Orthopaedic Web LinksOrthopaedic Oncology: Bone Cancer Benign Tumors and soft tissue neoplasms - Orthopaedic Web Links
Present achievements in the field of soft tissue tumors are the result of advances in molecular biology, oncogenetics, imaging techniques, immunochemistry, diagnosis by fine-needle aspiration, surgical reconstruction, radiation therapy, and tissue banking. Benign soft tissue tumors are fairly common and are treated with surgery alone. Prior to the 1970s, surgery ...
SC27- A Pattern-Based Approach to the Diagnosis of Soft Tissue Tumors, with an Emphasis on DifferentSC27- A Pattern-Based Approach to the Diagnosis of Soft Tissue Tumors, with an Emphasis on Different
NEW COURSE The diagnosis of soft tissue tumors can be a significant challenge, even to the experienced surgical pathologist, due to the broad morphologic spectrum of mesenchymal tumors and histologic overlap among soft tissue tumors and non-mesenchymal neoplasms. Furthermore, shared immunohistochemical features as well as genetic alterations are common. While current classification schemes guide the organization of most soft tissue tumors based on the line of differentiation exhibited by the tumor cells, for many soft tissue tumors, the lineage is not obvious. This course will teach a pattern-based approach to the evaluation of soft tissue tumors, guided by the predominant cytomorphology (i.e., epithelioid, spindle cell, pleomorphic, round cell), with an emphasis on the integration of clinical findings and morphologic features, as well as the judicious application of immunohistochemistry and other ancillary tests, particularly FISH, in differential diagnosis. The goal is to provide a practical ...
SC27-A Pattern-Based Approach to the Diagnosis of Soft Tissue TumorsSC27-A Pattern-Based Approach to the Diagnosis of Soft Tissue Tumors
Faculty: Leona A. Doyle, MD, and Jason L. Hornick, MD, PhD; Brigham and Womens Hospital, Harvard Medical School, Boston, MA The diagnosis of soft tissue tumors can be a significant challenge, even to the experienced surgical pathologist, due to the broad morphologic spectrum of mesenchymal tumors and histologic overlap among soft tissue tumors and non-mesenchymal neoplasms. Furthermore, shared immunohistochemical features as well as genetic alterations are common. While current classification schemes guide the organization of most soft tissue tumors based on the line of differentiation exhibited by the tumor cells, for many soft tissue tumors, the lineage is not obvious. This course will teach a pattern-based approach to the evaluation of soft tissue tumors, guided by the predominant cytomorphology (i.e., epithelioid, spindle cell, pleomorphic, round cell), with an emphasis on the integration of clinical findings and morphologic features, as well as the judicious application of ...
Synchronous Bony and Soft Tissue Metastases from Follicular Carcinoma of the Thyroid - Fingerprint - Manipal Academy of...Synchronous Bony and Soft Tissue Metastases from Follicular Carcinoma of the Thyroid - Fingerprint - Manipal Academy of...
Fingerprint Dive into the research topics of Synchronous Bony and Soft Tissue Metastases from Follicular Carcinoma of the Thyroid. Together they form a unique fingerprint. ...
Soft tissue tumors - Med NotesSoft tissue tumors - Med Notes
Treatment For treatment of soft tissue tumors used surgical, radiation and drug methods, and combinations thereof.The main treatment - benign soft tissue tumors and most malignant is surgical.. Surgical treatment is used in two forms: wide excision and amputation (disarticulation) limbs.. Indications and contraindications to a particular method of treatment is quite difficult.Wide excision is indicated for sarcomas is not very significant for the size of the tumor, located relatively shallow and retained displaceability in the absence of their germination in the main vessels, bone and nerve trunks.. amputation is shown in the following cases: 1) tumor can not be removed by wide excision;. 2) wide excision of the tumor to save the limb, which can not be used (poor circulation and nerve supply);. 3) failure of multiple intact operations;. 4) the palliative amputation due to bleeding, intolerable pain, smell (decay, bleeding tumors).. When performing a wide excision of the tumor should be removed ...
Soft tissue lesions in children: 2. Inflammation and infection. - Semantic ScholarSoft tissue lesions in children: 2. Inflammation and infection. - Semantic Scholar
Semantic Scholar extracted view of Soft tissue lesions in children: 2. Inflammation and infection. by Maureen E Grundy et al.
Magnetic resonance imaging of soft-tissue tumors of the extremities: A practical approach<...Magnetic resonance imaging of soft-tissue tumors of the extremities: A practical approach<...
TY - JOUR. T1 - Magnetic resonance imaging of soft-tissue tumors of the extremities. T2 - A practical approach. AU - Chan, Wing P.. PY - 2013/12/28. Y1 - 2013/12/28. N2 - Diagnosis of extremity soft-tissue tumors can be challenging. Characteristics of tumor margins can help precisely identify locally aggressive or non-aggressive behavior for surgical planning, but cannot differentiate benign from malignant lesions. Most malignant tumors can have inhomogeneous signals on T2-weighted images. Although a uniform signal on T2-weighted images can be a reliable indication of a benign lesion, a well-defined mass with homogeneous internal signal intensity does not definitively identify a benign lesion. Some common and distinctive soft-tissue lesions can have specific clinical and imaging features allowing a diagnosis without biopsy. These are known as determinate lesions. This illustrative report presents a diagnostic guide for extremity soft-tissue tumors based on tissue signal and morphological ...
2017 07 25 012017 07 25 01
Leesburg, VA, July 25, 2017-Better understanding of practical imaging techniques with regard to neonatal soft-tissue tumors can improve patient care, according to an article published in the July 2017 issue of the American Journal of Roentgenology (AJR). Neonatal soft-tissue tumors are congenital neoplasms discovered during the first month of life. Because of their rarity, these tumors often pose diagnostic challenges for clinicians and specialists, including radiologists. "From an epidemiologic point of view, there has been no unified method of reporting neonatal soft-tissue tumors. As a result, the exact prevalence, sites of origin, and pathologic nature of the tumors are unknown," said the articles lead author, Dr. Richard Restrepo, of the Department of Radiology, Nicklaus Childrens Hospital, of Miami, Florida.. Titled "Up-To-Date Practical Imaging Evaluation of Neonatal Soft-Tissue Tumors: What Radiologists Need to Know," the article noted that neonatal soft-tissue tumors are a unique set ...
Sabinet | Injecting soft tissue lesions with confidence: the wristSabinet | Injecting soft tissue lesions with confidence: the wrist
Once again, comparative illustrations and detailed information on technique permit successful injection of the soft tissues to relieve the symptoms of carpal tunnel syndrome and tenosynovitis of the thumb.
Doppler Ultrasound in Characterization of Superficial Soft Tissue Masses - Tabular View - ClinicalTrials.govDoppler Ultrasound in Characterization of Superficial Soft Tissue Masses - Tabular View - ClinicalTrials.gov
There are many examples for these benign superficial soft tissue lesions as lipoma, ganglion, Bakers cyst, giant cell tumor, lymphangioma, hernia, abscess, epidermoid cyst, hematoma, muscle rupture, glomus tumor, fibromatosis, lymphadenitis hemangioma, exostosis, fibroma, neurofibroma and schwannoma. Malignant lesions also could be seen as lymphoma, metastasis, osteogenic sarcoma, liposarcoma , leiomyosarcoma, rhabdomyosarcoma and synovial sarcoma.. Nowadays, High resolution ultrasound has a high sensitivity in detecting superficial soft tissue masses through the grey-scale grading that compose an image range from pure black at the weakest intensity to pure white at the strongest that can be used to evaluate its structure, some aspects of its function and to determine the nature of a mass lesion (cystic or solid) and with Doppler ultrasound which is an excellent imaging modality to determine the vascularity of superficial soft tissue masses that can be characterized in terms of their ...
No questions in Soft Tissue Neoplasms - lookformedical.comNo questions in Soft Tissue Neoplasms - lookformedical.com
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
圖書館館藏資料查詢系統圖書館館藏資料查詢系統
ps: Includes bibliographical references and index. How and when to biopsy the skin -- Benign melanocytic proliferations and precursor lesions to melanoma -- Melanoma : classic subtypes -- Histological and phenotypic variants of melanoma and of the borderline melanocytic tumor -- Prognosticators of melanoma, the melanoma report, and the sentinel lymph node -- Basal cell carcinoma : clinical features, histology, and biology -- Squamous cell carcinoma and its precursors -- Benign adnexal neoplasms -- Malignant adnexal neoplasms -- Soft tissue neoplasms of the skin and superficial subcutis -- Medicolegal aspects of neoplastic dermatology. ...
Interferon Alfa With or Without Isotretinoin in Treating Patients With Metastatic Kidney Cancer - Full Text View -...Interferon Alfa With or Without Isotretinoin in Treating Patients With Metastatic Kidney Cancer - Full Text View -...
DISEASE CHARACTERISTICS: Histologically confirmed metastatic renal cell adenocarcinoma Histologic confirmation of metastases desirable Progression of metastases within 2 months of study No clinically manifest CNS metastasis Bidimensionally measurable metastases, as follows: Lung lesion with diameter greater than 2 cm Superficial lymph node or skin or subcutaneous lesion with diameter greater than 2.5 cm Lymph node in the mediastinum or retroperitoneal region, liver lesion, or soft tissue lesion visible on CT or ultrasound with initial diameter greater than 2.5 cm No bone lesion without surrounding, measurable soft tissue lesion. PATIENT CHARACTERISTICS: Age: 18 to 75 Performance status: WHO 0 or 1 Life expectancy: At least 90 days Hematopoietic: WBC greater than 3,000/mm3 OR Absolute granulocyte count greater than 1,500/mm3 OR Platelet count greater than 100,000/mm3 Hepatic: Bilirubin no greater than 1.1 mg/dL Lipids no greater than 1.5 times normal Renal: Creatinine no greater than 1.6 mg/dL ...
Soft Tissue Sarcoma and Bone Surgery | NorthShoreSoft Tissue Sarcoma and Bone Surgery | NorthShore
Soft tissue includes connective tissue, muscle, fat, nerves and blood vessels that perform important functions throughout the body. Benign tumors can potentially develop within any of these systems. Benign soft tissue tumors are more common, including lipomas (fatty tissue), hemangiomas (blood vessels) and leiomyomas (smooth muscles). These benign tumors require an accurate diagnosis and at times, removal to prevent progression.. The malignant form of soft tissue cancer, sarcoma, can also evolve from any of these structures, but is most commonly located in the extremities (arms and legs) and abdomen. Abdominal sarcomas can extend to involve nearby organs, requiring removal or presurgical treatment. Surgery is an important component of sarcoma treatment. At NorthShore, our cancer surgeons have expertise to treat this disease and work collaboratively with plastic surgeons, radiation oncologists and medical oncologists. For extremity sarcomas, our fellowship trained surgeons focus on limb salvage ...
Epithelioid sarcoma pulmonary metastases | Radiology Case | Radiopaedia.orgEpithelioid sarcoma pulmonary metastases | Radiology Case | Radiopaedia.org
Epithelioid sarcoma is a rare soft tissue tumor with unclear histogenesis that represents the most common soft tissue sarcoma of a hand. This tumor is often mistaken for a chronic inflammatory process or necrotizing granuloma due to its innocuous...
Pediatric Musculoskeletal (MSK) Soft Tissue Tumor and Mimics on Apple BooksPediatric Musculoskeletal (MSK) Soft Tissue Tumor and Mimics on Apple Books
‎Pediatric Musculoskeletal (MSK) Soft Tissue Tumor and Mimics  is a radiographic atlas with cross-sectional correlation, mostly MR. The major goal of this book is to expose readers to the range of different musculoskeletal soft tissue tumor with emphasis on the most common ones in pediatric p…
Whole-body MR in Staging Bone and Soft Tissue Metastases in Breast Cancer Patients(MetaMaRBo)Whole-body MR in Staging Bone and Soft Tissue Metastases in Breast Cancer Patients(MetaMaRBo)
Prospective MR-imaging study : role of magnetic resonance (MR) and Diffusion weighted imaging (DWI) MR in staging and therapy assessment in breast cance
MRIMS JournalMRIMS Journal
Kishori D1, Sudhir Kumar V2, Indira V3 1Assistant Prof, 2Associate Prof, 3Prof and HOD, Department of Pathology, Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad.. Abstract:. Desmoid are rare soft tissue tumours most commonly seen in females between 20-40 years of age.They are known for their infiltrative pattern of growth and local recurrence. Diagnosis through clinical presentation imaging and histopathology forms the key to differentiate Desmoid tumours from other soft tissue sarcomas like Fibro sarcomas to offer correct treatment.Here we report one such case of Desmoid tumour of the anterior abdominal wall in a female patient which was removed by radical resection.. Key words: Desmoid tumour, abdominal wall, local recurrence, spindle shaped cells.. Corresponding Author: Dr. Kishori D, Department of Pathology, Malla Reddy Institute of Medical Sciences, Hyderabad. Email: [email protected] ...
Approach to the Diagnosis of Soft Tissue Tumors | Basicmedical KeyApproach to the Diagnosis of Soft Tissue Tumors | Basicmedical Key
Clinical Information The diagnosis of a soft tissue lesion requires a modicum of clinical information and adequate, well-processed tissue. At a minimum, the pathologist should be apprised of patient age, tumor location, and its growth characteristics. In some cases, the results of imaging studies, particularly magnetic resonance imaging (MRI), enhance ones understanding of the clinical…
Rabbit polyclonal to EREG - mTOR inhibitors suppress homologous recombination repairRabbit polyclonal to EREG - mTOR inhibitors suppress homologous recombination repair
Multiple myeloma is from the existence of lytic bone tissue lesions usually. with MBD including bone tissue pain, lytic bone tissue lesions, pathologic fractures, and hypercalcemia. MM bone tissue lesions result not merely from the immediate sediment of multiple myeloma cells inside the bone tissue, but also in the discharge of soluble elements by both tumor as well as the bone tissue microenvironment which bring about arousal of osteoclast activity and bone tissue resorption. Typical radiographs from the skeleton are obtained following diagnosis of individuals with myeloma routinely. Unusual skeletal radiographs are discovered in a lot more than 80% of sufferers. The skeletal X-ray adjustments in multiple myeloma range between apparently normal bone fragments to extensive bone tissue lesions with concomitant pathological fractures [1]. Durie and Salmon discovered that the extant of bone tissue lesions correlated highly with tumor insert and prognosis and for that reason radiograph adjustments ...
Patent US7001380 - Electrosurgical system and method - Google PatentsPatent US7001380 - Electrosurgical system and method - Google Patents
A method is disclosed for treating benign conditions, such as enlarged tonsils and/or adenoids located in a patients throat or nasopharynx, or soft tissue lesions located in a patients oropharynx or larynx. According to the method, a space containing the patients nasopharynx, oropharynx or pharynx and larynx is isolated from the patients trachea and lungs using an inflatable cuff tracheostomy tube or nasotracheal tube inserted in the patients trachea. The cuff is inflated to occlude the trachea. The patient is placed in a supine position, whereupon at least a portion of the space containing the nasopharynx and/or oropharynx and larynx is filled with saline. An endoscope is then inserted into the space to view the operative site in which the tonsils or tissue lesion are to be treated. An electrosurgical instrument having an active tissue treatment electrode and a return electrode connected to an electrosurgical generator is then inserted into the space, either along side the endoscope or through the
Bone and Soft Tissue Tumor Team | Orthopaedics and Rehabilitation | OHSUBone and Soft Tissue Tumor Team | Orthopaedics and Rehabilitation | OHSU
Information about the care team for bone and soft tissue tumors. The team includes orthopaedic surgeons and advanced practice providers as well as oncologists, musculoskeletal radiologists, radiation oncologists, surgical oncologists, and bone and soft tissue pathologists.
Halaven® (Eribulin) Demonstrates Overall Survival Benefit in Rare Soft Tissue Sarcoma Sub-types | ANP Pers Support | De kortste...Halaven® (Eribulin) Demonstrates Overall Survival Benefit in Rare Soft Tissue Sarcoma Sub-types | ANP Pers Support | De kortste...
HATFIELD, England, October 11, 2015 /PRNewswire/ -- FOR EU MEDIA ONLY: NOT FOR SWISS OR AUSTRIAN JOURNALISTS Five abstracts highlight
ECR 2019 / C-1792 / Is MRI diffusion-weighted imaging a reliable tool for the diagnosis and post therapeutic follow up of...ECR 2019 / C-1792 / Is MRI diffusion-weighted imaging a reliable tool for the diagnosis and post therapeutic follow up of...
Poster: ECR 2019 / C-1792 / Is MRI diffusion-weighted imaging a reliable tool for the diagnosis and post therapeutic follow up of extremity soft‑tissue neoplasms? by: A. F. I. Moustafa, R. A. Zeitoun, A. Shokry, M. M. A. Rezk; Cairo/EG
MedPix Case - Renal Cell Carcinoma with lytic metastasisMedPix Case - Renal Cell Carcinoma with lytic metastasis
Soft tissue mass measuring 3.3 cm in the long dimension with cortical destruction adjacent to or within the posterolateral right third rib. Evidence of soft tissue lesion with lytic destruction of lateral 10th rib noted concerning for neoplasm. Lungs are clear and evenly aerated with normal cardiac and mediastinal contours. No evidence of perihilar adenopathy.
Tumor Surgery > Tumor Education > Soft Tissue Tumors > Soft Tissue Tumor Types > Dedifferentiated...Tumor Surgery > Tumor Education > Soft Tissue Tumors > Soft Tissue Tumor Types > Dedifferentiated...
On May 10th I had the pleasure of meeting Dr. Wittig for the first time. This was an extremely stressful time for me since I had received several reports regarding my cancer diagnosis. Upon meeting Dr, Wittig I immediately knew I was in good hands. His calm demeanor & straightforward manner were very comforting to me. He laid out how he was going to proceed with the operation, how long it would take, & followup. He has been a source of comfort to me thru out this ordeal & I know I could not be in a better place with him. His support staff of nurses, is top notch. Their attention to detail, answering questions we may have, are always done in a timely manner. Without the ease of working with Dr. James Wittig, I can tell you. I would not feel as confident with my situation as I do. He is truly a very special human being. Sincerely, Karolyn ...
Bone Tumors and Soft Tissue Tumors | Seattle Childrens HospitalBone Tumors and Soft Tissue Tumors | Seattle Children's Hospital
Experts at Seattle Childrens diagnose and treat all types of bone and soft tissue tumors, both cancerous (malignant) and noncancerous (benign).
PPT - Diagnosis and Management of Bone and Soft Tissue Tumors PowerPoint presentation | free to view - id: 71390-ZDc1ZPPT - Diagnosis and Management of Bone and Soft Tissue Tumors PowerPoint presentation | free to view - id: 71390-ZDc1Z
Diagnosis and Management of Bone and Soft Tissue Tumors - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 71390-ZDc1Z
Magnetic Resonance Imaging of Bone and Soft Tissue Tumors and Their Mimics: A Clinical Atlas by A. D. Degryse, A. M. A. de...Magnetic Resonance Imaging of Bone and Soft Tissue Tumors and Their Mimics: A Clinical Atlas by A. D. Degryse, A. M. A. de...
Find great deals for Magnetic Resonance Imaging of Bone and Soft Tissue Tumors and Their Mimics: A Clinical Atlas by A. D. Degryse, A. M. A. de Schepper (Paperback, 2011). Shop with confidence on eBay!
ProActive Sports Rehabs Anthony Goode Completes Graston Technique Training Course | Business | South Buffalo NewsProActive Sports Rehab's Anthony Goode Completes Graston Technique Training Course | Business | South Buffalo News
Anthony T. Goode, PT/ATC, co-owner of ProActive Sports Rehab, recently completed Graston Technique M1-Basic Training and is now treating patients with GT. Graston Technique is a unique, evidence-based form of instrument-assisted soft tissue mobilization that enables clinicians to effectively and efficiently address soft tissue lesions and fascial restrictions resulting in improved patient outcomes.. "Graston Technique can be used to treat any movement system dysfunction that has been determined to have a soft tissue component," said Goode.. The technique uses specially-designed stainless steel instruments with unique treatment edges and angles to deliver an effective means of manual therapy. The use of the GT instruments, when combined with appropriate therapeutic exercise, leads to the restoration of pain-free movement and function.. The technique also improves diagnostic treatment, increases patient satisfaction by achieving notably faster and better outcomes, speeds rehabilitation and ...
The bioelectric correlates of musculoskeletal injury and repair. - Surrey Research Insight Open AccessThe bioelectric correlates of musculoskeletal injury and repair. - Surrey Research Insight Open Access
There is a need for outcome measurement tools which are able to provide accurate and reliable information regarding the efficiency and efficacy of therapeutic intervention of soft tissue injury e.g. ligament tear. Electrical activity within the body tissues has been shown to be influenced by the tissue state, and following injury, bioelectric changes have been demonstrated for example in bone healing and nerve regeneration. This project considers the relationship between the electrical potentials recorded from the skin surface and clinical recovery following a soft tissue lesion. The measurement of the skin potential is not new but the application and approach used is novel in that a non invasive differential skin surface potential is used instead of the traditional and invasive transcutaneous potential. The differential potential was initially investigated in non injured subjects in order to gain an understanding of its character and behaviour. Simultaneous monitoring of environmental, ...
Equine Regenerative Medicine | Burleson Equine HospitalEquine Regenerative Medicine | Burleson Equine Hospital
The use of PRP for the treatment of a variety of soft tissue tendon and ligament injuries is rapidly expanding. After taking a sample of the patients blood, in minutes a portable filtration system separates blood plasma rich in platelets from red blood cells. This PRP, along with its associated growth factors, is then immediately injected via ultrasound guided techniques into the soft tissue lesions creating what some call a "super-clot" that serves to help create a biologic scaffold upon which the bodys own cells migrate. These cells produce new collagen fibrils along lines of tension in the structure being treated. Sometimes even used in conjunction with stem cell treatment, PRP is a fast, inexpensive treatment that uses the horses own cells and molecules to stimulate more rapid and stronger healing in a variety of structures. We use this often for flexor tendon core lesions and suspensory ligament desmitis.. ...
Resources - Graston Technique®Resources - Graston Technique®
Graston Technique® (GT) is a unique, evidence-based form of instrument-assisted soft tissue mobilization that enables clinicians to effectively and efficiently address soft tissue lesions and fascial restrictions resulting in improved patient outcomes.GT uses specially designed stainless steel instruments with unique treatment edges and angles to deliver an effective means of manual therapy. The use of GT instruments, when combined with appropriate therapeutic exercise, leads to the restoration of pain-free movement and function. The instruments also are used diagnostically to assess the kinetic chain, in an efficient manner using the principles of regional interdependence. ...
Patients - Graston Technique®Patients - Graston Technique®
Graston Technique® (GT) is a unique, evidence-based form of instrument-assisted soft tissue mobilization that enables clinicians to effectively and efficiently address soft tissue lesions and fascial restrictions resulting in improved patient outcomes. GT uses specially designed stainless steel instruments with unique treatment edges and angles to deliver an effective means of manual therapy. The use of GT instruments, when combined with appropriate therapeutic exercise, leads to the restoration of pain-free movement and function. The instruments also are used diagnostically to assess the kinetic chain, in an efficient manner using the principles of regional interdependence. ...
MS Cytotechnology Molecular Cytology Curriculum | Albany College of Pharmacy and Health SciencesMS Cytotechnology Molecular Cytology Curriculum | Albany College of Pharmacy and Health Sciences
This course presents the basic principles of cytopathology applied to the cellular samples obtained through fine needle aspiration (FNA) from a variety of body sites where lesions can be identified by Radiological techniques. Gross and microscopic anatomy, physiology and pathology of these sites will be explored. Specimens from the Liver, Pancreas, Ovary, Kidney Adrenal Glands and Central Nervous System will be examined. The course will also include FNA of unusual lesions like: mediastinal lesions, bone and soft tissue lesions and pediatric tumors. Benign, reactive and infectious conditions will be discussed. Infectious organisms and the cellular changes they produce will be identified. Atypical and malignant conditions and their cellular appearance will be explored. Cellular changes induced by therapies and environmental entities will be discussed and their role in rendering a final diagnosis will be recognized. In the laboratory students will learn in an experiential setting by examining both ...
Gists As a Cause of Massive Bleeding - Polish Journal of Surgery - Volume 79, Issue 8 (2007) - PSJD - YaddaGists As a Cause of Massive Bleeding - Polish Journal of Surgery - Volume 79, Issue 8 (2007) - PSJD - Yadda
This report describes two cases of GIST with bleeding as the predominant symptom. The first case comprised a patient with a gastric carcinoma and bleeding of the digestive tract. The second patient was diagnosed with mesenteric carcinoma and peritoneal cavity bleeding. Both patients underwent emergent surgical intervention. The first patient was subjected to gastric resection, while the latter to mesentery resection. The postoperative period proved uneventful. The excised specimens were evaluated at the Department of Pathomorphology, Institute of Oncology in Warsaw. The patients were directed to the Department of Soft Tissue Neoplasms, Institute of Oncology for registration and further treatment ...
need help with excision of lesionneed help with excision of lesion
Excision of lesions confuse me. Need other coders opinions. Looking at 11442. procedure: benign right ear skin and soft tissue lesion excision 1 x 05
Equine | OrthoVetSuperSiteEquine | OrthoVetSuperSite
BACKGROUND: Osteochondral fragmentation of the dorsoproximal margin of the proximal phalanx is commonly recognised in racing Thoroughbreds. Frequency distribution has been documented in racing Thoroughbreds and Quarter Horses in the USA and in European Warmbloods but no data have been published from the UK. Concurrent intra-articular soft tissue lesions and radiographic accuracy of fragment distribution in racing Thoroughbreds have not previously been reported. ...
Benign soft-tissue tumors in a large referral population : distribution of specific diagnoses by age, sex, and location. | Base...Benign soft-tissue tumors in a large referral population : distribution of specific diagnoses by age, sex, and location. | Base...
OBJECTIVE. The purpose of this study was to determine the specific diagnoses, relative prevalence, and the age, sex, and skeletal distribution of benign soft-tissue tumors and to ascertain the relative frequency of these tumors in specific anatomic locations and age groups among a population of patients in a large pathologic consultation...
JCI - Melanoma immunotherapy using mature DCs expressing the constitutive proteasomeJCI - Melanoma immunotherapy using mature DCs expressing the constitutive proteasome
Vaccination stimulated antigen-specific T cell responses in all subjects, which peaked after 3-4 vaccinations, but remained elevated in Arm C subjects. Also in Arm C, circulating melanoma cell levels (as detected by quantitative PCR) fell, and T cell lytic activity against autologous melanoma was induced. In HLA-A2+ subjects, CD8+ T cells that bound tetramers loaded with cP-derived melanoma antigenic peptides were found in the peripheral blood only in Arm C subjects. Of 2 subjects with active disease (both in Arm C), one had a partial clinical response, while the other, who exhibited diffuse dermal and soft tissue metastases, had a complete response. ...
JCI - Melanoma immunotherapy using mature DCs expressing the constitutive proteasomeJCI - Melanoma immunotherapy using mature DCs expressing the constitutive proteasome
Vaccination stimulated antigen-specific T cell responses in all subjects, which peaked after 3-4 vaccinations, but remained elevated in Arm C subjects. Also in Arm C, circulating melanoma cell levels (as detected by quantitative PCR) fell, and T cell lytic activity against autologous melanoma was induced. In HLA-A2+ subjects, CD8+ T cells that bound tetramers loaded with cP-derived melanoma antigenic peptides were found in the peripheral blood only in Arm C subjects. Of 2 subjects with active disease (both in Arm C), one had a partial clinical response, while the other, who exhibited diffuse dermal and soft tissue metastases, had a complete response. ...
JCI - WelcomeJCI - Welcome
Vaccination stimulated antigen-specific T cell responses in all subjects, which peaked after 3-4 vaccinations, but remained elevated in Arm C subjects. Also in Arm C, circulating melanoma cell levels (as detected by quantitative PCR) fell, and T cell lytic activity against autologous melanoma was induced. In HLA-A2+ subjects, CD8+ T cells that bound tetramers loaded with cP-derived melanoma antigenic peptides were found in the peripheral blood only in Arm C subjects. Of 2 subjects with active disease (both in Arm C), one had a partial clinical response, while the other, who exhibited diffuse dermal and soft tissue metastases, had a complete response. ...
வார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியாவார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியா
இப்பக்கத்தைக் கடைசியாக 5 திசம்பர் 2013, 09:18 மணிக்குத் திருத்தினோம் ...
Melanoma, Skin, and Soft Tissue Tumors | John Wayne Cancer InstituteMelanoma, Skin, and Soft Tissue Tumors | John Wayne Cancer Institute
Explore all of the conditions that are treated at the JWCI Melanoma Center of Excellence, a world-renowned institute for the treatment of melanomas.
David Joyce (United States) | Lipomatous soft tissue tumors - Are we doing too much surgery? - ΕRASMUS CONFERENCES & EVENTS SADavid Joyce (United States) | Lipomatous soft tissue tumors - Are we doing too much surgery? - ΕRASMUS CONFERENCES & EVENTS SA
At Erasmus, our vision is to become the leading Professional Congress Organiser in Greece and one of the top ten Professional Congress Organisers globally, while conducting our business with professionalism, ethics and responsibility towards our people (personnel), our clients and the society ...
DI-fusion In vitro characterisation of soft tissue tumor chemosensitivity.DI-fusion In vitro characterisation of soft tissue tumor chemosensitivity.
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] | PeaceHealthAdult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] | PeaceHealth
Adult soft tissue sarcoma is a disease in which malignant (cancer) cells form in the soft tissues of the body. The soft tissues of the body include the muscles, tendons (bands of fiber that connect muscles to bones), fat, blood vessels, lymph vessels, nerves, and tissues around joints. Adult soft tissue sarcomas can...
Giant pilomatrixoma looks like a malignant soft tissue tumor: a case report, European Journal of Plastic Surgery | 10.1007...Giant pilomatrixoma looks like a malignant soft tissue tumor: a case report, European Journal of Plastic Surgery | 10.1007...
Read "Giant pilomatrixoma looks like a malignant soft tissue tumor: a case report, European Journal of Plastic Surgery" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Auburn Community HospitalAdult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Auburn Community Hospital
Incidence and Mortality Estimated new cases and deaths from soft tissue sarcoma in the United States in 2018:[ 1 ] New cases: 13,040. Deaths: 5,150. Soft tissue sarcomas are malignant tumors that arise in any of the mesodermal tissues of the extremities (50%), trunk and retroperitoneum (40%), or head and neck (10%). The...
Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI]Adult Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI]
Incidence and Mortality Estimated new cases and deaths from soft tissue sarcoma in the United States in 2020:[ 1] New cases: 13,130. Deaths: 5,350. Soft tissue sarcomas are malignant tumors that arise in any of the mesodermal tissues of the extremities (50%), trunk and retroperitoneum (40%), or head and neck (10%). The...
Pazopanib: New Drug for Advanced Soft-tissue Sarcoma - The ASCO PostPazopanib: New Drug for Advanced Soft-tissue Sarcoma - The ASCO Post
In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs.. Indication. In April 2012, pazopanib (Votrient) was approved for the treatment of patients with advanced soft-tissue sarcoma who have received prior chemotherapy.1,2 The efficacy of pazopanib for the treatment of patients with adipocytic soft-tissue sarcoma or gastrointestinal stromal tumors has not been demonstrated. Pazopanib has a prior indication in the treatment of advanced renal cell carcinoma.. Approval in advanced soft-tissue sarcoma was based on a multicenter trial in which 369 patients with metastatic soft-tissue sarcoma who had received prior chemotherapy including an anthracycline were randomly assigned (2:1) to receive double-blind oral pazopanib at 800 mg once daily (n = 246) or placebo (n = 123).2 Treatment was continued until disease progression, ...
Adult soft tissue sarcomaAdult soft tissue sarcoma
Soft tissue sarcoma (STS) is cancer that forms in the soft tissue of the body. Soft tissue connects, supports, or surrounds other body parts. In adults, STS is rare. There are many different types of soft tissue cancers. The type of sarcoma depends on the tissue it forms in:MusclesTendonsFatBlood vesselsLymph vesselsNervesTissues in and around...
Individualized treatment of advanced/metastatic adult soft tissue sarcomas | Klinikai OnkológiaIndividualized treatment of advanced/metastatic adult soft tissue sarcomas | Klinikai Onkológia
Considering the extreme histological heterogeneity of soft tissue sarcomas (STS), their management is an art of its own. Over the last decade the treatment of STSs has been slowly shifting towards a more individualized, histology driven tailored approach. With the availability of novel antineoplastic agents and the differential sensitivity of different subtypes of sarcomas to these drugs, we aim to provide some guidance in terms of optimal sequencing of therapies. Furthermore, we discuss some of the emerging targeted therapies currently evaluated for the palliative treatment of the more common and some of the very rare STS subtypes.. ...
YEUNGNAM UNIVERSITY: Cytologic Findings of Alveolar Soft Part Sarcoma Presenting with Multiple Pulmonary Masses - A Case Report...YEUNGNAM UNIVERSITY: Cytologic Findings of Alveolar Soft Part Sarcoma Presenting with Multiple Pulmonary Masses - A Case Report...
Alveolar soft part sarcoma (ASPS) is a rare malignant soft tissue tumor of uncertain origin, and it has a strong propensity for metastasis to the lungs, bones and brain. We report upon an unusual case of ASPS, presenting as multiple lung nodules with no other detectable primary site, in a 44-year-old man. A fine needle aspiration of the nodules yielded scattered, discohesive cells, each containing an eccentrically displaced nucleus and prominent nucleolus, on a granular background. Tumor cells with numerous bared nuclei, and occasional sheets of epithelioid cells were also found. Under the cytological diagnosis of an unclassified epithelioid malignant tumor, resection of the lung nodules was performed. The histologic findings were consistent with ASPS, showing positive TFE3-nuclear immunoreactivity. There is limited literature concerning cytological findings associated with pulmonary ASPS: especially in cases where the primary site is unknown. Here, we present a cytological review of pulmonary ...
ILovemyMOM - Family/Friend: Sarcoma - Adult Soft Tissue Cancer | Epithelioid Sarcoma- Currently in active treatment (initial...ILovemyMOM - Family/Friend: Sarcoma - Adult Soft Tissue Cancer | Epithelioid Sarcoma- Currently in active treatment (initial...
ILovemyMOM - Family/Friend: Sarcoma - Adult Soft Tissue Cancer > Epithelioid Sarcoma Patient Info: Currently in active treatment (initial surgery, receiving chemo rounds/radiation), Diagnosed: over 6 years ago, Female, Age: 70
Molly - Family/Friend: Sarcoma - Adult Soft Tissue Cancer- Newly diagnosed (has not begun treatment)Molly - Family/Friend: Sarcoma - Adult Soft Tissue Cancer- Newly diagnosed (has not begun treatment)
Molly - Family/Friend: Sarcoma - Adult Soft Tissue Cancer Patient Info: Newly diagnosed (has not begun treatment), Diagnosed: over 9 years ago, Female, Age: 59
Tumor Oxygenation Predicts for the Likelihood of Distant Metastases in Human Soft Tissue Sarcoma | Cancer ResearchTumor Oxygenation Predicts for the Likelihood of Distant Metastases in Human Soft Tissue Sarcoma | Cancer Research
This study was performed to explore the relationship between tumor oxygenation and treatment outcome in human soft tissue sarcoma. Twenty-two patients with nonmetastatic, high-grade, soft tissue sarcomas underwent preoperative irradiation and hyperthermia and pretreatment measurement of tumor oxygenation. The 18-month actuarial disease-free survival was 70% for patients with tumor median oxygen pressure (pO2) values of ,10 mm Hg but only 35% for those with median pO2 values of , 10 mm Hg (P = 0.01). There were eight treatment failures; the first site of recurrence was lung in all patients. Median pO2 was 7.5 mm Hg for metastasizing tumors versus 20 mm Hg for nonmetastasizing tumors (P = 0.03). Potential mechanisms and implications for clinical trial design are discussed.. ...
p53 Mutation and MDM2 Amplification in Human Soft Tissue Sarcomas | Cancer Researchp53 Mutation and MDM2 Amplification in Human Soft Tissue Sarcomas | Cancer Research
The p53 and MDM2 genes were analyzed in 24 human soft tissue sarcomas (11 malignant fibrous histiocytomas and 13 liposarcomas). Alterations of p53, consisting of point mutations, deletions, or overexpression, were detected in one-third (8 of 24) of the sarcomas. MDM2 gene amplification was detected in another 8 tumors, but no tumor contained an alteration of both genes. Monoclonal antibodies reactive with the human MDM2 gene product were developed, and immunohistochemical analysis revealed nuclear localization and overexpression of MDM2 in those tumors with amplified MDM2 genes. These data support the hypothesis that p53 and MDM2 genetic alterations are alternative mechanisms for inactivating the same regulatory pathway for suppressing cell growth.. ...
High-risk Soft Tissue Sarcoma Patients Benefit from Targeted Heat Therapy Combined with ChemotherapyHigh-risk Soft Tissue Sarcoma Patients Benefit from Targeted Heat Therapy Combined with Chemotherapy
A technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with localized, high-risk soft tissue sarcoma, according to the results of a study recently published in the journal The Lancet.[1] These findings were initially presented on September 22, 2009 at Europes largest cancer congress, ECCO 15-ESMO 34, in Berlin.[2]. Soft tissue sarcomas are cancers that affect the connective and supportive tissues, which include bones, muscles, tendons, ligaments, fat, blood vessels, and fibrous tissues. Sarcomas are relatively uncommon, but when they do occur, they tend to affect children and young adults. The primary treatment for sarcoma is surgery; however, because of the difficulty in removing these tumors, they are often treated with radiation and chemotherapy as well. Survival for this disease varies depending on the location and size of the tumor. Patients who are considered high-risk typically relapse within two or three years.. Regional ...
Management of Soft Tissue Sarcoma, 2nd EditionManagement of Soft Tissue Sarcoma, 2nd Edition
Management of Soft Tissue Sarcoma addresses the diagnosis and best current management of adult soft tissue sarcomas. Edited by world renowned experts, this book delineates and discusses each different sarcoma subtype individually. Both clinical and molecular diagnoses are addressed, and tumor histopathology is employed as the basis of treatment recommendations including surgery, radiation therapy, systemic therapy and novel therapeutics. ...
2016. Jönsson L et al. - Cost of treatment in patients with metastatic soft tissue sarcoma who respond favourably to...2016. Jönsson L et al. - Cost of treatment in patients with metastatic soft tissue sarcoma who respond favourably to...
2016. Jönsson L et al. - Cost of treatment in patients with metastatic soft tissue sarcoma who respond favourably to chemotherapy. The Sarcoma treatment and Burden of Illness in North America and Europe (SABINE) study | Mapi: Health Research & Commercialization
Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trialMorphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial
Morphotek, Inc. announced today that it has commenced a multi-center, Phase II study evaluating the safety and efficacy of MORAb-004 when combined with gemcitabine and docetaxel in the treatment of metastatic soft tissue sarcoma.
Mole Removal Causes Pediatric Patient To Suffer Facial NecrosisMole Removal Causes Pediatric Patient To Suffer Facial Necrosis
I am a pediatric plastic and craniofacial surgeon. My practice consists of a majority of pediatric cases, many of which are nevus and soft tissue lesion cases. I have been in practice for 7 years, 2 years in academics and 5 years in hospital-based practice. I am currently the medical director of a childrens hospital cleft lip and palate team. My practice consists of approximately 75% pediatric patients and 25% adult patients. I excise pigmented nevi and other soft tissue lesions over 100 times per year. I remove larger nevi requiring serial excision perhaps 5-6 times per year. The largest nevi that require tissue expanders to recruit skin prior to excision are rarer, and I do perhaps only 2-3 per year. I do, however, have extensive, frequent experience with using tissue expanders for a variety of other reasons, such as breast reconstruction. The principles and practices of tissue expansion are the same, regardless of the reason for using them or the location.. Large, pigmented nevi historically ...
High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities | OncogeneHigh prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities | Oncogene
Soft tissue sarcomas are a heterogenous group of neoplasms with various histological subtypes. Up to now, no individual causal molecular markers for prognosis and therapeutic success have been identified. A tumorigenic connection between the oncogene product Mdm2 and tumor suppressor p53 is generally accepted, but their possible clinical relevance has not yet been investigated sufficiently in soft tissue sarcoma. In 86 primary soft tissue sarcoma of the extremities (RO-resected, T1/2 N0 M0), Mdm2 and p53 overexpression were investigated by immunohistochemistry. The results were adjusted to clinico-pathological characteristics and evaluated for their prognostic relevance by multivariate analysis. In Coxs multivariate analysis with stratification of Mdm2 to p53 results, we determined four groups which had different prognostic values for relapse-free and overall survival (Mdm2−/p53−|Mdm2−/p53+ |Mdm2+/p53−|Mdm2+/p53+). The most striking finding was a relative risk (rr) for overall survival of 18.77
Doxorubicin versus CYVADIC versus doxorubicin plus ifisfamide in first-line treatment of advanced soft tissue sarcomas: a...Doxorubicin versus CYVADIC versus doxorubicin plus ifisfamide in first-line treatment of advanced soft tissue sarcomas: a...
Doxorubicin versus CYVADIC versus doxorubicin plus ifisfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group ...
Symptoms of Soft Tissue Sarcoma - RightDiagnosis.comSymptoms of Soft Tissue Sarcoma - RightDiagnosis.com
Symptoms of Soft Tissue Sarcoma including 9 medical symptoms and signs of Soft Tissue Sarcoma, alternative diagnoses, misdiagnosis, and correct diagnosis for Soft Tissue Sarcoma signs or Soft Tissue Sarcoma symptoms.
Management of giant intermuscular lipoma of hips: A case report and review of literatureManagement of giant intermuscular lipoma of hips: A case report and review of literature
Lipomas are the most common benign soft tissue tumors that may occur anywhere in the body, and are mostly found within the subcutaneous areas. However, compared to common inter-muscular lipomas, giant, deep-seated lipomas of the hip are even more infrequent and thus easily misdiagnosed. In this study, we presented an adult female patient with an unusually large, deep intermuscular lipoma in the left hip that led the initial misdiagnosis.. Due to the rare location, intermuscular giant lipomas are easily overlooked when making primary diagnosis upon admission. To differentiate from other soft tissue tumors, auxiliary examinations including ultrasonography, CT and magnetic resonance imaging (MRI) are needed, which may improve the diagnosis, as well as an appropriate staging of the tumor extension and involved structures. Ultrasonography of the lipomas is often the initial diagnostic procedure due to its availability and cost-effectiveness, when compared with CT and MRI. Generally, lipomas have been ...
Primary Synovial Sarcoma of the Scalp: An Unusual PresentationPrimary Synovial Sarcoma of the Scalp: An Unusual Presentation
... Synovial sarcomas are a rare subset of malignant soft tissue tumors, with an estimated incidence of 2.75 p..
Short Communication - Rare oral soft tissue metastasis: An overview | AbstractShort Communication - Rare oral soft tissue metastasis: An overview | Abstract
Metastasis means that cancer spreads to a different body part from where it started. When this happens, doctors say the cancer has
MRIMS JournalMRIMS Journal
Kishori D1, Sudhir Kumar V2, Indira V3 1Assistant Prof, 2Associate Prof, 3Prof and HOD, Department of Pathology, Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad.. Abstract:. Desmoid are rare soft tissue tumours most commonly seen in females between 20-40 years of age.They are known for their infiltrative pattern of growth and local recurrence. Diagnosis through clinical presentation imaging and histopathology forms the key to differentiate Desmoid tumours from other soft tissue sarcomas like Fibro sarcomas to offer correct treatment.Here we report one such case of Desmoid tumour of the anterior abdominal wall in a female patient which was removed by radical resection.. Key words: Desmoid tumour, abdominal wall, local recurrence, spindle shaped cells.. Corresponding Author: Dr. Kishori D, Department of Pathology, Malla Reddy Institute of Medical Sciences, Hyderabad Email: [email protected] Introduction:. Desmoid tumors are rare locally invasive neoplasms constituting 3% of the ...
A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma...A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma...
Rhabdomyosarcoma (RMS) is the most common malignant soft tissue tumor in children and is highly resistant to all forms of treatment currently available once metastasis or relapse has commenced. As it has recently been determined that the acetylcholine receptor (AChR) γ-subunit, which defines the fetal AChR (fAChR) isoform, is almost exclusively expressed in RMS post partum, we recombinantly fused a single chain variable fragment (scFv) derived from a fully human anti-fAChR Fab-fragment to Pseudomonas exotoxin A to generate an anti-fAChR immunotoxin (scFv35-ETA).While scFv35-ETA had no damaging effect on fAChR-negative control cell lines, it killed human embryonic and alveolar RMS cell lines in vitro and delayed RMS development in a murine transplantation model. These results indicate that scFv35-ETA may be a valuable new therapeutic tool as well as a relevant step towards the development of a fully human immunotoxin directed against RMS. Moreover, as approximately 20% of metastatic malignant melanomas
Soft tissue sarcoma | Teenage Cancer TrustSoft tissue sarcoma | Teenage Cancer Trust
Soft tissue sarcomas are cancerous tumours that form in places like fat and muscle. Read about symptoms, diagnosis and treatment for soft tissue sarcomas.
I Have Soft Tissue SarcomasI Have Soft Tissue Sarcomas
Do You Have Soft Tissue Sarcomas? Join friendly people sharing true stories in the I Have Soft Tissue Sarcomas group. Find support forums, advice and chat with groups who share this life experience. A Soft Tissue Sarcomas anonymous support group with...
Wound complications following pre-operative radiotherapy for soft tissue sarcoma<...Wound complications following pre-operative radiotherapy for soft tissue sarcoma<...
TY - JOUR. T1 - Wound complications following pre-operative radiotherapy for soft tissue sarcoma. AU - Kunisada, T.. AU - Ngan, S. Y.. AU - Powell, G.. AU - Choong, Peter F.M.. PY - 2002/2. Y1 - 2002/2. N2 - Aims: We analysed wound complications in 43 patients with soft tissue sarcoma who were treated with combined pre-operative radiotherapy and surgery. Methods: All patients received the same protocol of pre-operative radiotherapy at our institution. Results: Thirty-six (84%) patients developed acute skin toxicity following radiotherapy. After wide local excision, 15 patients required primary soft tissue reconstruction with vascularized muscle transfer and four patients underwent free skin flap to enable wound closure as part of their primary surgery. Nineteen patients (44%) developed post-operative wound complications including 10 (23%) patients who required an additional surgical procedure. Four (27%) patients developed flap necrosis in a group of 15 who underwent primary vascularized soft ...
Proliferation and Survival Mechanisms in Soft Tissue Sarcoma and Gliob by Vera Mucaj"Proliferation and Survival Mechanisms in Soft Tissue Sarcoma and Gliob" by Vera Mucaj
Soft tissue sarcomas and glioblastomas are two deadly tumors that are characterized by aggressive overproliferation, and regions of severe intratumoral nutrient and oxygen deprivation. The mechanisms by which tumors evade proliferation control signals and survive in a hostile microenvironment are active areas of investigation. This work describes two projects investigating loss of proliferation control in soft tissue sarcoma, as a result of Hippo pathway deregulation, and mechanisms of survival under stress in glioblastoma, as a result of decreased microRNA-124 (miR-124) levels. First, we demonstrate that the Hippo pathway is deregulated in soft tissue sarcoma patient samples, leading to overexpression of the Hippo effector YAP. YAP, a transcriptional coactivator, binds to TEAD proteins in the nucleus and controls the transcription of multiple pro-proliferation and anti-apoptosis targets, including the transcription factor FOXM1. Interestingly, we show that FOXM1 physically interacts with the TEAD/YAP
Trabectedin with or without prophylactic dexamethasone in patients with recurrent advanced soft tissue sarcoma. - AdisInsightTrabectedin with or without prophylactic dexamethasone in patients with recurrent advanced soft tissue sarcoma. - AdisInsight
This study will investigate the efficacy, tolerability and pharmacokinetics of trabectedin +/- dexamethasone in patients with advanced soft-tissue sarcoma.
Soft tissue sarcomas of infancy<...Soft tissue sarcomas of infancy<...
TY - JOUR. T1 - Soft tissue sarcomas of infancy. AU - Palumbo, J. S.. AU - Zwerdling, Theodore. PY - 1999. Y1 - 1999. N2 - Malignancy occurring during the neonatal period (defined as the first 28 days of life) is over 3 times the incidence of other pediatric age groups. Of all neoplasia occurring in infants, benign and malignant, 25% are soft tissue tumors. Differentiating the benign lesions from the 15% that are malignant can be difficult. This article discusses the epidemiology, differential diagnosis, evaluation, and treatment of infants with soft tissue sarcomas. Fibrosarcoma and rhabdomyosarcoma are also discussed at length. The authors review other rare tumors as well. The impact on diagnosis of molecular techniques is included when appropriate. A multidisciplinary team approach for treatment of these infants is recommended.. AB - Malignancy occurring during the neonatal period (defined as the first 28 days of life) is over 3 times the incidence of other pediatric age groups. Of all ...
Plus itPlus it
The standard of care for patients with advanced soft-tissue sarcoma is treatment with first-line chemotherapeutic agents such as doxorubicin. However, clinical response to these drugs is limited and is often accompanied by toxic side effects. Soft-tissue sarcomas are characterized by significant tumor hypoxia, which has been associated with chemotherapy resistance, metastasis, and poor prognosis, suggesting that targeting the hypoxic tumor microenvironment may be beneficial. Chawla and colleagues assessed the safety and efficacy of first-line treatment with doxorubicin in combination with TH-302, a prodrug that is preferentially activated under hypoxia to generate a cytotoxic alkylating active metabolite, in an open-label, single-arm phase II trial of 91 patients with advanced soft-tissue sarcoma. Compared with historical outcomes of response to doxorubicin treatment, patients receiving combination therapy exhibited a higher six-month progression-free survival (PFS) rate of 58%, a median PFS of ...
Plus itPlus it
The standard of care for patients with advanced soft-tissue sarcoma is treatment with first-line chemotherapeutic agents such as doxorubicin. However, clinical response to these drugs is limited and is often accompanied by toxic side effects. Soft-tissue sarcomas are characterized by significant tumor hypoxia, which has been associated with chemotherapy resistance, metastasis, and poor prognosis, suggesting that targeting the hypoxic tumor microenvironment may be beneficial. Chawla and colleagues assessed the safety and efficacy of first-line treatment with doxorubicin in combination with TH-302, a prodrug that is preferentially activated under hypoxia to generate a cytotoxic alkylating active metabolite, in an open-label, single-arm phase II trial of 91 patients with advanced soft-tissue sarcoma. Compared with historical outcomes of response to doxorubicin treatment, patients receiving combination therapy exhibited a higher six-month progression-free survival (PFS) rate of 58%, a median PFS of ...
soft tissue sarcoma & Cancer read more in the post : ResultDon | | Results, Exams, Education, Jobssoft tissue sarcoma & Cancer read more in the post : ResultDon | | Results, Exams, Education, Jobs
A sarcoma is a type of cancer that develops from certain tissues, like bone or muscle. There are 2 main types of sarcoma: bone sarcomas and soft tissue sarcomas. Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. They can be found in any part of the body. Most of them develop in the arms or legs. They can also be found in the trunk, head and neck area, internal organs, and the area in back of the abdominal cavity (known as the retroperitoneum). Sarcomas are not common tumors, and most cancers are the type of tumors called carcinomas ...
ICD-10-CM Code M70.831 - Other soft tissue disorders related to use, overuse and pressure, right forearmICD-10-CM Code M70.831 - Other soft tissue disorders related to use, overuse and pressure, right forearm
M70.831 is a billable code used to specify a medical diagnosis of other soft tissue disorders related to use, overuse and pressure, right forearm. Code valid for the year 2020
Combined modality treatment of extremity soft tissue sarcomas | SpringerLinkCombined modality treatment of extremity soft tissue sarcomas | SpringerLink
Background:Substantial progress has been made in the multimodality treatment of soft tissue sarcoma over the past decade. This review summarizes current state-of-the-art management for patients with...
Soft Tissue Sarcoma - Lahey Hospital & Medical Center, Burlington & PeabodySoft Tissue Sarcoma - Lahey Hospital & Medical Center, Burlington & Peabody
Soft tissue sarcoma is a disease in which cancer cells are found in soft tissue in the body. Soft tissue includes muscles, tendons, connective tissue, fat, blood vessels, nerves, and joint tissue. There are many types of soft tissue sarcoma.
Olaratumab Approved to Treat Advanced Soft Tissue Sarcoma - GuidingLightBooks.com®Olaratumab Approved to Treat Advanced Soft Tissue Sarcoma - GuidingLightBooks.com®
The Food and Drug Administration (FDA) has granted accelerated approval to olaratumab (Lartruvo®) for the treatment of some patients with soft tissue sarcoma. ...
Maffuccis Syndrome - Port Washington, NY PodiatristMaffucci's Syndrome - Port Washington, NY Podiatrist
Maffuccis Syndrome is a very rare form of enchondromatosis that combines multiple enchondromas in bones anywhere in the body with benign soft tissue tumors (known as hemangiomas), which are associated with blood vessels. This condition tends to appear in the hands and feet, and has a greater tendency toward malignant transformation than Olliers Disease ...
Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue SarcomaBrostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial t
Novel molecular multilevel targeted antitumor agents Sonawane P, Choi YA, Pandya H, Herpai DM, Fokt I, Priebe W, Debinski W -...Novel molecular multilevel targeted antitumor agents Sonawane P, Choi YA, Pandya H, Herpai DM, Fokt I, Priebe W, Debinski W -...
Cancer Transl Med, Official publication of Chinese Translational Medicine and Biology Technology Innovation Alliance, and Cipher Ground
Soft Tissue Sarcoma Surgery | Condition at Yale MedicineSoft Tissue Sarcoma Surgery | Condition at Yale Medicine
Soft tissue sarcomas are cancerous tumors that form in the cells that make up the bodys connective tissues. Surgery is a common treatment.
CASO Oncology | Tenet Florida Physician ServicesCASO Oncology | Tenet Florida Physician Services
The surgical oncologists at the Center for Advanced Surgical Oncology are specially trained in common and complex cancer surgery utilizing some of the latest technology. These techniques include robotic-assisted procedures, laparoscopic, open or hybrid approaches, alone, or in combination with, intraoperative radiation therapy, microwave ablation and intraoperative ultrasound. The broad range of procedures includes minimally invasive intra-abdominal gastrointestinal surgery, endocrine tumors, retroperitoneal and extremity soft tissue neoplasms, as well as the entire range of skin tumors. Our experts use some of the latest surgical advances and minimally invasive surgical techniques to diagnose, stage and treat benign and malignant tumors. Our surgeons are trained and have significant experience with surgical procedures that include:. ...
Nonrhabdomyosarcoma Soft Tissue Sarcomas Treatment & Management: Medical Care, Surgical Care, ConsultationsNonrhabdomyosarcoma Soft Tissue Sarcomas Treatment & Management: Medical Care, Surgical Care, Consultations
Soft tissue sarcomas, the fifth most common solid tumors in children, are relatively rare and account for about 6-7% of all childhood malignancies. About half of these tumors are rhabdomyosarcomas, and nonrhabdomyosarcoma soft tissue sarcomas (NRSTSs) account for the remainder (ie, about 4% of childhood malignancies).
Li-Fraumeni syndromeLi-Fraumeni syndrome
Li-Fraumeni syndromeLi-Fraumeni syndrome
NeoplasmNeoplasm
Granular cell tumorGranular cell tumor
Perivascular epithelioid cell tumourPerivascular epithelioid cell tumour
Oncogenic osteomalaciaOncogenic osteomalacia
Joseph F. Fraumeni Jr.Joseph F. Fraumeni Jr.
Kostniakomięsak, wolna encyklopediaKostniakomięsak, wolna encyklopedia
NeoplasmNeoplasm
C49C49
ICD-10 Chapter II: NeoplasmsICD-10 Chapter II: Neoplasms
Malignant rhabdoid tumourMalignant rhabdoid tumour
International Classification of Childhood CancerInternational Classification of Childhood Cancer
Ectopic salivary gland tissueEctopic salivary gland tissue
List of ICD-9 codes 140-239: neoplasmsList of ICD-9 codes 140-239: neoplasms
Vascular anomalyVascular anomaly
Acute myeloid dendritic cell leukemiaAcute myeloid dendritic cell leukemia
Dermatofibrosarcoma protuberansDermatofibrosarcoma protuberans
Subcutaneous emphysemaSubcutaneous emphysema
Glomus tumorGlomus tumor
Veterinary oncologyVeterinary oncology
Stafne defectStafne defect
Follicular dendritic cell sarcomaFollicular dendritic cell sarcoma
EpithelioidEpithelioid
Frederick Pei LiFrederick Pei Li
வார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியாவார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியா
FibromaFibroma
DermatofibromaDermatofibroma
AdenomyomaAdenomyoma
Impacted wisdom teethImpacted wisdom teeth
Brain tumorBrain tumor
Category:Cancer - Simple English Wikipedia, the free encyclopediaCategory:Cancer - Simple English Wikipedia, the free encyclopedia
Platelet-derived growth factorPlatelet-derived growth factor
Radiation therapyRadiation therapy
سرطان پروستات - ویکی‌پدیا، دانشنامهٔ آزادسرطان پروستات - ویکی‌پدیا، دانشنامهٔ آزاد
ThymusThymus
ಟೆಂಪ್ಲೇಟು:Central nervous system navs - ವಿಕಿಪೀಡಿಯಟೆಂಪ್ಲೇಟು:Central nervous system navs - ವಿಕಿಪೀಡಿಯ
Lichen planusLichen planus
ಆಸ್ಟಿಯೊಪೊರೋಸಿಸ್‌ - ವಿಕಿಪೀಡಿಯಆಸ್ಟಿಯೊಪೊರೋಸಿಸ್‌ - ವಿಕಿಪೀಡಿಯ
AutopsyAutopsy
Aphthous stomatitisAphthous stomatitis
William ColeyWilliam Coley
FibroadenomaFibroadenoma
Dentin hypersensitivityDentin hypersensitivity
ಶಸ್ತ್ರಚಿಕಿತ್ಸೆ - ವಿಕಿಪೀಡಿಯಶಸ್ತ್ರಚಿಕಿತ್ಸೆ - ವಿಕಿಪೀಡಿಯ
Skin cancerSkin cancer
Black hairy tongueBlack hairy tongue
Mouth ulcerMouth ulcer
Vascular anomalyVascular anomaly
RhinoplastyRhinoplasty
Lead poisoningLead poisoning
MastopexyMastopexy
DysplasiaDysplasia
GingivitisGingivitis
ThyroidThyroid
Sarcoma botryoidesSarcoma botryoides
Herpes simplexHerpes simplex
Eagle syndromeEagle syndrome
Mdm2Mdm2
Mammary tumorMammary tumor
زونا - ویکی‌پدیا، دانشنامهٔ آزادزونا - ویکی‌پدیا، دانشنامهٔ آزاد
Chest radiographChest radiograph
PathologyPathology
Behçets diseaseBehçet's disease
HerpanginaHerpangina
間皮瘤 - 维基百科，自由的百科全书間皮瘤 - 维基百科，自由的百科全书
Template:Joint navs - 维基百科，自由的百科全书Template:Joint navs - 维基百科，自由的百科全书
RhinoplastyRhinoplasty
User:Djd/sandbox/MedNav/Pathology templatesUser:Djd/sandbox/MedNav/Pathology templates
Granulosa cell tumourGranulosa cell tumour
AbfractionAbfraction
MelanomaMelanoma
ಅಂಡವಾಯು - ವಿಕಿಪೀಡಿಯಅಂಡವಾಯು - ವಿಕಿಪೀಡಿಯ
Canine histiocytic diseasesCanine histiocytic diseases
List of vaginal tumorsList of vaginal tumors
Kasvaja - VikipeediaKasvaja - Vikipeedia
Kopliks spotsKoplik's spots
Herpes labialisHerpes labialis
CD117 - WikipédiaCD117 - Wikipédia
PlateletPlatelet
Burning mouth syndromeBurning mouth syndrome
Temporomandibular joint dysfunctionTemporomandibular joint dysfunction
ಟೆಂಪ್ಲೇಟು:Connective tissue - ವಿಕಿಪೀಡಿಯಟೆಂಪ್ಲೇಟು:Connective tissue - ವಿಕಿಪೀಡಿಯ
PlateletPlatelet
Connective tissueConnective tissue
NeurooncologyNeurooncology
Idiopathic osteosclerosisIdiopathic osteosclerosis
Cervical cancerCervical cancer
Prostate cancerProstate cancer
Plasma cell dyscrasiaPlasma cell dyscrasia
H19 (gene)H19 (gene)
Ceruminous adenocarcinomaCeruminous adenocarcinoma
Idiopathic orbital inflammatory diseaseIdiopathic orbital inflammatory disease
Epithelioid sarcomaEpithelioid sarcoma
List of MeSH codes (C04)List of MeSH codes (C04)
ToothacheToothache
Salivary gland tumourSalivary gland tumour
1p36 deletion syndrome1p36 deletion syndrome
PhotoagingPhotoaging
Tumoral calcinosisTumoral calcinosis
GPR128GPR128
ThyroidThyroid
DiathermyDiathermy
EctomesenchymomaEctomesenchymoma
OsteosarcomaOsteosarcoma
Renal cell carcinomaRenal cell carcinoma
Ovarian cystOvarian cyst
OsteoblastomaOsteoblastoma
Breast reductionBreast reduction
Neuroendocrine adenoma middle earNeuroendocrine adenoma middle ear
FibroadenomaFibroadenoma
MLANAMLANA
Grading (tumors)Grading (tumors)
ASPSCR1ASPSCR1
Keratin 5Keratin 5
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
Soft Tissue NeoplasmsNeoplasms, Connective and Soft TissueNeoplasms, Bone TissueNeoplasms, Gonadal TissueNeoplasms, Adipose TissueNeoplasms, Nerve TissueNeoplasms, Connective TissueNeoplasms, Vascular TissueNeoplasms, Fibrous TissueSarcomaNeoplasms, Muscle TissueSoft Tissue InjuriesSoft Tissue InfectionsLiposarcoma, MyxoidLipomaConnective TissuePalatal NeoplasmsCystadenomaAdenoma, PleomorphicTissue BanksBiopsy, Fine-NeedleThoraxNeoplasms, Second PrimaryInternational Classification of DiseasesConnective Tissue DiseasesNeoplasmsManuscripts, MedicalVaccinationPapillomavirus InfectionsUterine Cervical DiseasesPapillomaviridaeUterine Cervical NeoplasmsPapillomavirus VaccinesAnus Diseasesraf KinasesProto-Oncogene Proteins c-rafNeurofibromatosis 1ras ProteinsNeoplasm TransplantationGliomaNeurofibromatosis 2Contrast MediaCapillary PermeabilityGadolinium DTPAMagnetic Resonance ImagingMagnetic Resonance AngiographyImage EnhancementBlood VolumeHeavy Ion RadiotherapyHeavy IonsCarbonChordomaRelative Biological Effectiveness
Orthopaedic Oncology: Bone Cancer Benign Tumors and soft tissue neoplasms - Orthopaedic Web LinksOrthopaedic Oncology: Bone Cancer Benign Tumors and soft tissue neoplasms - Orthopaedic Web Links
Soft Tissue NeoplasmsSoft Tissue Neoplasms
No questions in Soft Tissue Neoplasms - lookformedical.comNo questions in Soft Tissue Neoplasms - lookformedical.com
Malignant soft tissue neoplasms. Problems with combined therapy. Radiologic diagnosis and radiotherapy]. - Semantic ScholarMalignant soft tissue neoplasms. Problems with combined therapy. Radiologic diagnosis and radiotherapy]. - Semantic Scholar
2017 07 25 012017 07 25 01
வார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியாவார்ப்புரு:Soft tissue tumors and sarcomas - தமிழ் விக்கிப்பீடியா
PPT - Diagnosis and Management of Bone and Soft Tissue Tumors PowerPoint presentation | free to view - id: 71390-ZDc1ZPPT - Diagnosis and Management of Bone and Soft Tissue Tumors PowerPoint presentation | free to view - id: 71390-ZDc1Z
Gastric Soft Tissue Neoplasms 2017-Sept. 23, 2017 - MHRIGastric Soft Tissue Neoplasms 2017-Sept. 23, 2017 - MHRI
ICD-10 Code for Other benign neoplasms of connective and other soft tissue- D21- Codify by AAPCICD-10 Code for Other benign neoplasms of connective and other soft tissue- D21- Codify by AAPC
ICD-9 Code 171.6 -Malignant neoplasm of connective and other soft tissue of pelvis- Codify by AAPCICD-9 Code 171.6 -Malignant neoplasm of connective and other soft tissue of pelvis- Codify by AAPC
ICD-9-CM Diagnosis Code 171.5 : Malignant neoplasm of connective and other soft tissue of abdomenICD-9-CM Diagnosis Code 171.5 : Malignant neoplasm of connective and other soft tissue of abdomen
2018 ICD-10-CM Diagnosis Code C49: Malignant neoplasm of other connective and soft tissue2018 ICD-10-CM Diagnosis Code C49: Malignant neoplasm of other connective and soft tissue
2018 ICD-10-CM Diagnosis Code D20: Benign neoplasm of soft tissue of retroperitoneum and peritoneum2018 ICD-10-CM Diagnosis Code D20: Benign neoplasm of soft tissue of retroperitoneum and peritoneum
JCDR - Cutaneous fibrous histiocytoma, Dermatofibroma, Soft tissue neoplasmJCDR - Cutaneous fibrous histiocytoma, Dermatofibroma, Soft tissue neoplasm
SOFT TISSUE NEOPLASMS | SelfDecode | Genome AnalysisSOFT TISSUE NEOPLASMS | SelfDecode | Genome Analysis
Soft Tissue Neoplasms | Colorado PROFILESSoft Tissue Neoplasms | Colorado PROFILES
Cases reported • Neoplasms, Connective and Soft TissueCases reported • Neoplasms, Connective and Soft Tissue
IMSEAR at SEARO: Soft tissue neoplasms: a clinicopathological studyIMSEAR at SEARO: Soft tissue neoplasms: a clinicopathological study
Soft Tissue Neoplasms -- surgery (Concept) - University of Missouri LibrariesSoft Tissue Neoplasms -- surgery (Concept) - University of Missouri Libraries
Recent questions in Neoplasms, Connective and Soft Tissue - lookformedical.comRecent questions in Neoplasms, Connective and Soft Tissue - lookformedical.com
En bloc resection of extra-peritoneal soft tissue neoplasms incorporating a type III internal hemipelvectomy: a novel approach ...En bloc resection of extra-peritoneal soft tissue neoplasms incorporating a type III internal hemipelvectomy: a novel approach ...
Gastric and Soft Tissue Neoplasms 2019 - MedStar Health - Continuing Medical Education (CME)Gastric and Soft Tissue Neoplasms 2019 - MedStar Health - Continuing Medical Education (CME)
C49.3 MALIGNANT NEOPLASM OF CONNECTIVE AND SOFT TISSUE OF THORAXC49.3 MALIGNANT NEOPLASM OF CONNECTIVE AND SOFT TISSUE OF THORAX
IMSEAR at SEARO: Benign vs malignant soft tissue neoplasms: Limitations of magnetic resonance imaging.IMSEAR at SEARO: Benign vs malignant soft tissue neoplasms: Limitations of magnetic resonance imaging.
ICD-10 Code D20.1 - Benign neoplasm of soft tissue of peritoneumICD-10 Code D20.1 - Benign neoplasm of soft tissue of peritoneum
Soft-Tissue Sarcomas, Breast Cancer, and Other NeoplasmsA Familial Syndrome? | Annals of Internal Medicine | American College...Soft-Tissue Sarcomas, Breast Cancer, and Other NeoplasmsA Familial Syndrome? | Annals of Internal Medicine | American College...
ICD-10 Code: C49.9 - Malignant neoplasm of connective and soft tissue, unspICD-10 Code: C49.9 - Malignant neoplasm of connective and soft tissue, unsp
ICD-10 Code: C49.4 - Malignant neoplasm of connective and soft tissue of abdomenICD-10 Code: C49.4 - Malignant neoplasm of connective and soft tissue of abdomen
ICD-10 Diagnosis Code D21.9 Benign neoplasm of connective and other soft tissue, unspICD-10 Diagnosis Code D21.9 Benign neoplasm of connective and other soft tissue, unsp
ICD-10-CM Code C49.4 - Malignant neoplasm of connective and soft tissue of abdomenICD-10-CM Code C49.4 - Malignant neoplasm of connective and soft tissue of abdomen
Histopathology of Preclinical Toxicity Studies : Interpretation and Relevance in Drug Safety Evaluation. (eBook, 2014) ...Histopathology of Preclinical Toxicity Studies : Interpretation and Relevance in Drug Safety Evaluation. (eBook, 2014) ...
Foreign body granuloma mimicking a soft tissue neoplasm | International Journal of Research in Health SciencesForeign body granuloma mimicking a soft tissue neoplasm | International Journal of Research in Health Sciences
Feasibility of ExAblate MRI Guided High Intensity Focused Ultrasound Tx of Soft Tissue Tumors - Full Text View - ClinicalTrials...Feasibility of ExAblate MRI Guided High Intensity Focused Ultrasound Tx of Soft Tissue Tumors - Full Text View - ClinicalTrials...
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TumorsMetastaticExtremitiesMetastasesMusculoskeletalClinicalSuperficialLesionSarcomaTable of NeoplasmsCutaneousGastric and soft tissue nePathologyAdiposeMesenchymal originDiseasesRadiotherapyIMSEAR at SEAROSubcutaneous tissueBenign and MalignantHead and NeckVena cavaMalignant softPrimarySpindle cellCongenitalSurgerySarcomas of the extremitiesSituMesothelial
Tumors5
Metastatic1
Extremities1
Metastases1
Musculoskeletal1
Clinical2
Superficial1
  • It is also useful to recall that when carcinomas or melanomas metastasize to soft tissue, they do so usually as small, superficial nodules rather than as large, deeply situated masses. (basicmedicalkey.com)
Lesion1
Sarcoma31
Table of Neoplasms2
Cutaneous2
Gastric and soft tissue ne1
  • Identify the different types of gastric and soft tissue neoplasms. (cloud-cme.com)
Pathology2
Adipose3
Mesenchymal origin2
Diseases1
Radiotherapy6
IMSEAR at SEARO1
Subcutaneous tissue1
Benign and Malignant1
Head and Neck2
Vena cava1
Malignant soft6
Primary4
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
  • The increased familial susceptibility to cancer was manifested not only by the large number of members affected but by a seeming excess of multiple primary neoplasms. (annals.org)
  • AYA neoplasms also differ from those in middle-aged and elderly people, in whom malignancies of epithelial cell origin or carcinomas of several primary sites account for more than 85% of cancers ( 3 ). (scielo.br)
  • We use primary organoid cultures of diverse tissues and tumor biopsies for immunotherapy modeling, oncogene functional screening and stem cell biology. (stanford.edu)
Spindle cell2
Congenital1
Surgery3
Sarcomas of the extremities1
  • Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514. (springermedizin.at)
Situ3
Mesothelial1